# HISTORY 24 Mar 2016: Updated by: TOUCHUP-v1.15 14 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20151007: root_PTN000194698 has function copper ion binding (GO:0005507) 20151007: root_PTN000194698 has function oxidoreductase activity, oxidizing metal ions (GO:0016722) 20151007: Bacteria _PTN000194932 has function hydroquinone:oxygen oxidoreductase activity (GO:0052716) 20151007: Opisthokonta_PTN001709969 contributes to function iron ion transmembrane transporter activity (GO:0005381) 20151007: Opisthokonta_PTN001709969 has function ferroxidase activity (GO:0004322) 20151007: Opisthokonta_PTN000194700 has function hydroquinone:oxygen oxidoreductase activity (GO:0052716) # cellular_component 20151007: Bacteria _PTN000194932 is found in outer membrane-bounded periplasmic space (GO:0030288) 20151007: Opisthokonta_PTN001709969 is found in high-affinity iron permease complex (GO:0033573) 20151007: node_PTN001709970 is found in fungal-type vacuole membrane (GO:0000329) 20151007: Embryophyta_PTN000917683 is found in plant-type cell wall (GO:0009505) 20151007: Embryophyta_PTN000917683 is found in plasmodesma (GO:0009506) 20151007: node_PTN001710419 is found in anchored component of plasma membrane (GO:0046658) 20151007: node_PTN001709970 is NOT found in high-affinity iron permease complex (GO:0033573) # biological_process 20151007: Opisthokonta_PTN001709969 participates in iron assimilation by reduction and transport (GO:0033215) 20151007: Opisthokonta_PTN001709969 participates in iron ion transport (GO:0006826) 20151007: node_PTN001365298 participates in lignin biosynthetic process (GO:0009809) 20151007: Diptera_PTN000194726 participates in chitin-based cuticle development (GO:0040003) 20151007: Viridiplantae_PTN000194909 participates in lignin biosynthetic process (GO:0009809) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).