# HISTORY 24 Mar 2016: Updated by: TOUCHUP-v1.15 14 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20140729: root_PTN000179505 has function ATPase binding (GO:0051117) 20140729: root_PTN000179505 has function proton-transporting ATPase activity, rotational mechanism (GO:0046961) # cellular_component 20140729: root_PTN000179505 is found in vacuolar proton-transporting V-type ATPase complex (GO:0016471) 20140729: Fungi_PTN000908025 is found in fungal-type vacuole membrane (GO:0000329) 20140729: Opisthokonta_PTN000907964 is found in plasma membrane (GO:0005886) 20140729: Viridiplantae_PTN000179688 is found in plant-type vacuole (GO:0000325) 20140729: Bacteria _PTN000179707 is NOT found in vacuolar proton-transporting V-type ATPase complex (GO:0016471) 20140729: Archaea_PTN000179704 is NOT found in vacuolar proton-transporting V-type ATPase complex (GO:0016471) # biological_process 20140729: root_PTN000179505 participates in ATP synthesis coupled proton transport (GO:0015986) 20140729: root_PTN000179505 participates in vacuolar acidification (GO:0007035) 20140729: root_PTN000179505 participates in vacuolar proton-transporting V-type ATPase complex assembly (GO:0070072) 20140729: Bacteria _PTN000179707 does NOT participate in vacuolar proton-transporting V-type ATPase complex assembly (GO:0070072) 20140729: Archaea_PTN000179704 does NOT participate in vacuolar proton-transporting V-type ATPase complex assembly (GO:0070072) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).