# HISTORY 25 May 2016: Saved by pascalegaudet using Paint 2.0-beta19 24 Mar 2016: Updated by: TOUCHUP-v1.15 14 Mar 2016: Updated by: TOUCHUP-v1.14 07 May 2016: Updated by: TOUCHUP-v1.18 # molecular_function 20140913: Tetrapoda_PTN000236355 has function cytokine activity (GO:0005125) 20160525: root_PTN000172473 has function tRNA binding (GO:0000049) # cellular_component 20160525: root_PTN000172473 is found in methionyl glutamyl tRNA synthetase complex (GO:0017102) 20160525: root_PTN000172473 is found in aminoacyl-tRNA synthetase multienzyme complex (GO:0017101) 20160525: Tetrapoda_PTN000236355 is found in extracellular space (GO:0005615) # biological_process 20140913: Tetrapoda_PTN000236355 participates in inflammatory response (GO:0006954) 20160525: root_PTN000172473 participates in tRNA aminoacylation for protein translation (GO:0006418) 20160525: Dikarya_PTN000942492 participates in positive regulation of ligase activity (GO:0051351) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).