# HISTORY 10 Aug 2016: Saved by pascalegaudet using Paint 2.22 # molecular_function 20160808: root_PTN000170013 has function GTPase activity (GO:0003924) 20160809: root_PTN000170013 has function microtubule binding (GO:0008017) # cellular_component 20160809: Eukaryota_PTN000170085 is found in mitochondrion (GO:0005739) 20160809: root_PTN000170013 is found in cytoplasm (GO:0005737) 20160809: Eukaryota_PTN000745660 is found in cleavage furrow (GO:0032154) 20160809: Eukaryota_PTN001696340 is found in peroxisome (GO:0005777) 20160809: Eukaryota_PTN001696340 is found in chloroplast (GO:0009507) 20160809: Eukaryota_PTN000902245 is found in nucleus (GO:0005634) 20160810: Fungi_PTN000902252 is found in peroxisome (GO:0005777) 20160810: Eukaryota_PTN000170085 is found in mitochondrial membrane (GO:0031966) # biological_process 20160808: Eukaryota_PTN000170085 participates in membrane fusion (GO:0061025) 20160809: Fungi_PTN000902124 participates in mitochondrial fusion (GO:0008053) 20160809: Ascomycota_PTN000170318 participates in mitochondrial fission (GO:0000266) 20160809: Euteleostomi_PTN000170016 participates in response to virus (GO:0009615) 20160809: Eukaryota_PTN000745660 participates in mitotic cytokinesis (GO:0000281) 20160809: Eukaryota_PTN001696340 participates in chloroplast fission (GO:0010020) 20160809: Eukaryota_PTN001696340 participates in peroxisome fission (GO:0016559) 20160809: Euteleostomi_PTN000170016 participates in innate immune response (GO:0045087) 20160809: Euteleostomi_PTN000170016 participates in defense response to virus (GO:0051607) 20160810: root_PTN000170013 participates in organelle organization (GO:0006996) 20160810: root_PTN000170013 participates in organelle fission (GO:0048285) 20160810: Eukaryota_PTN000745660 does NOT participate in organelle fission (GO:0048285) 20160810: Eukaryota_PTN000902162 participates in mitochondrial fission (GO:0000266) 20160810: Fungi_PTN000902185 participates in peroxisome organization (GO:0007031) 20160810: Fungi_PTN000902252 participates in peroxisome organization (GO:0007031) 20160810: Fungi_PTN000902252 participates in peroxisome fission (GO:0016559) 20160810: Opisthokonta_PTN000902069 participates in mitochondrial fusion (GO:0008053) 20160810: Eukaryota_PTN000170085 participates in dynamin polymerization involved in mitochondrial fission (GO:0003374) 20160810: Metazoa_PTN001696079 participates in apoptotic mitochondrial changes (GO:0008637) 20160810: Metazoa_PTN001696087 participates in receptor internalization (GO:0031623) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).