# HISTORY 24 Mar 2016: Updated by: TOUCHUP-v1.15 14 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20151030: Euteleostomi_PTN000891751 has function bitter taste receptor activity (GO:0033038) 20151030: Theria _PTN000791590 has LOST/MODIFIED function bitter taste receptor activity (GO:0033038) 20151030: Boreoeutheria_PTN001685419 has LOST/MODIFIED function bitter taste receptor activity (GO:0033038) 20151030: Theria _PTN001685444 has LOST/MODIFIED function bitter taste receptor activity (GO:0033038) 20151030: Catarrhini_PTN000791238 has LOST/MODIFIED function bitter taste receptor activity (GO:0033038) # cellular_component 20151030: Euteleostomi_PTN000891751 is found in integral component of membrane (GO:0016021) # biological_process 20151030: Euteleostomi_PTN000891751 participates in detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580) 20151030: Theria _PTN000791590 does NOT participate in detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580) 20151030: Boreoeutheria_PTN001685419 does NOT participate in detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580) 20151030: Theria _PTN001685444 does NOT participate in detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580) 20151030: Catarrhini_PTN000791238 does NOT participate in detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).