# HISTORY 07 May 2016: Updated by: TOUCHUP-v1.18 14 Mar 2016: Updated by: TOUCHUP-v1.14 24 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function 20140613: root_PTN000145408 has function transporter activity (GO:0005215) 20140613: Eumetazoa_PTN000888455 has function monocarboxylic acid transmembrane transporter activity (GO:0008028) 20140613: Deuterostomia_PTN000145055 has function lactate transmembrane transporter activity (GO:0015129) 20140613: Euteleostomi_PTN000145267 has function thyroid hormone transmembrane transporter activity (GO:0015349) # cellular_component 20140613: root_PTN000145408 is found in integral component of membrane (GO:0016021) 20140613: Deuterostomia_PTN000145055 is found in integral component of plasma membrane (GO:0005887) 20140612: Fungi_PTN000888803 is found in integral component of fungal-type vacuolar membrane (GO:0071627) # biological_process 20140612: root_PTN000145408 participates in ion transmembrane transport (GO:0034220) 20140613: Bilateria_PTN000144718 participates in monocarboxylic acid transport (GO:0015718) 20140612: Deuterostomia_PTN000145055 participates in plasma membrane lactate transport (GO:0035879) 20140613: Dikarya_PTN000888324 participates in amino acid transmembrane export from vacuole (GO:0032974) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES MAF and PG 2014-06-13 # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).