# HISTORY
07 May 2016: Updated by: TOUCHUP-v1.18
24 Mar 2016: Updated by: TOUCHUP-v1.15
14 Mar 2016: Updated by: TOUCHUP-v1.14
07 May 2016: Updated by: TOUCHUP-v1.18

# molecular_function
20150710: root_PTN000136167 has function glutathione transferase activity (GO:0004364) 
20150710: Enterobacteriaceae_PTN001679905 has function glutathione disulfide oxidoreductase activity (GO:0015038) 
20150710: Enterobacteriaceae_PTN001679919 has function disulfide oxidoreductase activity (GO:0015036) 
20150710: Eukaryota_PTN000136176 has function translation elongation factor activity (GO:0003746) 
20150710: Bilateria_PTN000136443 has function chloride channel activity (GO:0005254) 
20150710: Pancrustacea_PTN000883986 has function glutathione peroxidase activity (GO:0004602) 
20150710: Chordata_PTN000883818 has function glutathione peroxidase activity (GO:0004602) 
20150710: Chordata_PTN000883818 has function maleylacetoacetate isomerase activity (GO:0016034) 
20150710: Gammaproteobacteria_PTN000137118 has function bacterial-type RNA polymerase core enzyme binding (GO:0001000) 
20150710: Enterobacteriaceae_PTN001681130 has function disulfide oxidoreductase activity (GO:0015036) 
20150710: Bilateria_PTN000136443 has LOST/MODIFIED function glutathione transferase activity (GO:0004364) 
20150710: node_PTN000883647 has LOST/MODIFIED function glutathione transferase activity (GO:0004364) 

# cellular_component
20150710: root_PTN000136167 is found in cytoplasm (GO:0005737) 
20150710: Eukaryota_PTN000136176 is found in nucleus (GO:0005634) 
20150710: Bilateria_PTN000136443 is found in nucleus (GO:0005634) 
20150710: Amniota_PTN000136474 is found in mitochondrion (GO:0005739) 
20150710: Chordata_PTN000883818 is found in mitochondrion (GO:0005739) 
20150710: Euteleostomi_PTN000136573 is NOT found in nucleus (GO:0005634) 
20150710: Euteleostomi_PTN000136447 is NOT found in nucleus (GO:0005634) 

# biological_process
20150710: root_PTN000136167 participates in glutathione metabolic process (GO:0006749) 
20150710: Embryophyta_PTN000883776 participates in protein glutathionylation (GO:0010731) 
20150710: Bilateria_PTN000136443 participates in chloride transmembrane transport (GO:1902476) 
20150710: Amniota_PTN000136474 participates in angiogenesis (GO:0001525) 
20150710: Euteleostomi_PTN000136573 participates in sensory perception of sound (GO:0007605) 
20150710: Tetrapoda_PTN000136574 participates in auditory receptor cell stereocilium organization (GO:0060088) 
20150710: Chordata_PTN000883818 participates in L-phenylalanine catabolic process (GO:0006559) 
20150710: Eukaryota_PTN001680376 participates in toxin catabolic process (GO:0009407) 
20150710: Bilateria_PTN000136443 does NOT participate in glutathione metabolic process (GO:0006749) 
# PRUNED
20150710: node_PTN000883647 does NOT participate in glutathione metabolic process (GO:0006749) 

07 May 2016: Poaceae_PTN001679860 has been pruned from tree
07 May 2016: node_PTN001344486 has been pruned from tree

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED

# NOTES
07 May 2016: Poaceae_PTN001679860 has been pruned from tree
07 May 2016: node_PTN001344486 has been pruned from tree
24 Mar 2016: node_PTN001344486 has been pruned from tree
24 Mar 2016: Poaceae_PTN001679860 has been pruned from tree
14 Mar 2016: Poaceae_PTN001679860 has been pruned from tree
14 Mar 2016: node_PTN001344486 has been pruned from tree

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).