# HISTORY 07 May 2016: Updated by: TOUCHUP-v1.18 14 Mar 2016: Updated by: TOUCHUP-v1.14 24 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function 20140729: node_PTN000126434 has function chitinase activity (GO:0004568) 20140729: node_PTN000126434 has function chitin binding (GO:0008061) 20140729: Arthropoda_PTN000829564 has function chitin deacetylase activity (GO:0004099) 20140729: Mammalia_PTN000126614 has LOST/MODIFIED function chitinase activity (GO:0004568) # cellular_component 20140729: node_PTN000126434 is found in extracellular region (GO:0005576) 20140729: Bilateria_PTN001341036 is found in cytoplasm (GO:0005737) # biological_process 20140729: node_PTN000126434 participates in chitin catabolic process (GO:0006032) 20140729: Deuterostomia_PTN000126443 participates in inflammatory response (GO:0006954) 20140729: Mammalia_PTN000126614 does NOT participate in chitin catabolic process (GO:0006032) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).