# molecular_function 20160304: root_PTN000125390 has function fatty acid elongase activity (GO:0009922) # cellular_component 20160304: root_PTN000125390 located in integral component of endoplasmic reticulum membrane (GO:0030176) # biological_process 20160304: root_PTN000125390 participates in sphingolipid biosynthetic process (GO:0030148) 20160304: root_PTN000125390 participates in fatty acid elongation, monounsaturated fatty acid (GO:0034625) 20160304: root_PTN000125390 participates in fatty acid elongation, saturated fatty acid (GO:0019367) 20160304: root_PTN000125390 participates in fatty acid elongation, polyunsaturated fatty acid (GO:0034626) 20160304: root_PTN000125390 participates in very long-chain fatty acid biosynthetic process (GO:0042761) # Notes Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).