# HISTORY 27 Oct 2016: Saved by mfeuerma using Paint 2.22 # molecular_function 20161027: root_PTN000124732 has function pseudouridine synthase activity (GO:0009982) # cellular_component 20161027: Eukaryota_PTN000124846 is found in cytoplasm (GO:0005737) 20161027: Eukaryota_PTN000124846 is found in nucleus (GO:0005634) 20161027: Eukaryota_PTN000124736 is found in nucleus (GO:0005634) # biological_process 20161027: root_PTN000124732 participates in tRNA pseudouridine synthesis (GO:0031119) 20161027: Eukaryota_PTN000124736 participates in mRNA pseudouridine synthesis (GO:1990481) 20161027: Eukaryota_PTN000124846 participates in mRNA pseudouridine synthesis (GO:1990481) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).