# HISTORY 26 May 2016: Saved by mfeuerma using Paint 2.0-beta19 # molecular_function 20160526: root_PTN000118466 has function nicotinamidase activity (GO:0008936) 20160526: Bacteria _PTN000118552 has LOST/MODIFIED function nicotinamidase activity (GO:0008936) 20160526: Bacteria _PTN000118552 has function 2,3-dihydroxybenzoate-serine ligase activity (GO:0047527) 20160526: Bacteria _PTN000118552 has function isochorismatase activity (GO:0008908) 20160526: Bacteria _PTN000118552 has function magnesium ion binding (GO:0000287) 20160526: Bacteria _PTN000118552 has function phosphopantetheine binding (GO:0031177) 20160526: node_PTN001669438 has LOST/MODIFIED function nicotinamidase activity (GO:0008936) 20160526: node_PTN000871599 has LOST/MODIFIED function nicotinamidase activity (GO:0008936) 20160526: node_PTN000871599 has function hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides (GO:0016811) # cellular_component 20160526: node_PTN001669438 is found in cytosol (GO:0005829) 20160526: Bacteria _PTN000118552 is found in cytosol (GO:0005829) 20160526: root_PTN000118466 is found in cytoplasm (GO:0005737) 20160526: Bacteria _PTN000118552 is found in plasma membrane (GO:0005886) 20160526: Eukaryota_PTN000118468 is found in nucleus (GO:0005634) # biological_process 20160526: root_PTN000118466 participates in nicotinamide metabolic process (GO:0006769) 20160526: root_PTN000118466 participates in NAD metabolic process (GO:0019674) 20160526: node_PTN001669438 does NOT participate in NAD metabolic process (GO:0019674) 20160526: node_PTN001669438 does NOT participate in nicotinamide metabolic process (GO:0006769) 20160526: Bacteria _PTN000118552 does NOT participate in NAD metabolic process (GO:0019674) 20160526: Bacteria _PTN000118552 does NOT participate in nicotinamide metabolic process (GO:0006769) 20160526: Bacteria _PTN000118552 participates in enterobactin biosynthetic process (GO:0009239) 20160526: Bacteria _PTN000118552 participates in phenazine biosynthetic process (GO:0002047) 20160526: node_PTN000871599 does NOT participate in NAD metabolic process (GO:0019674) 20160526: node_PTN000871599 does NOT participate in nicotinamide metabolic process (GO:0006769) 20160526: node_PTN000871599 participates in uracil catabolic process (GO:0006212) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).