# HISTORY
24 Mar 2016: Updated by: TOUCHUP-v1.15
14 Mar 2016: Updated by: TOUCHUP-v1.12

# molecular_function
20150909: Eukaryota_PTN000841430 has function transmembrane transporter activity (GO:0022857) 
20150909: Euteleostomi_PTN000841435 has function methotrexate transporter activity (GO:0015350) 
20150909: Euteleostomi_PTN000841435 has function reduced folate carrier activity (GO:0008518) 
20150909: Euteleostomi_PTN000841435 has function folic acid transporter activity (GO:0008517) 
20150909: Euteleostomi_PTN000841435 has function folic acid binding (GO:0005542) 
20150909: Euteleostomi_PTN000074528 has function thiamine uptake transmembrane transporter activity (GO:0015403) 
20150909: Euteleostomi_PTN000743341 has function thiamine uptake transmembrane transporter activity (GO:0015403) 

# cellular_component
20150909: Eukaryota_PTN000841430 is found in integral component of plasma membrane (GO:0005887) 

# biological_process
20150909: Eukaryota_PTN000841430 participates in transmembrane transport (GO:0055085) 
20150909: Euteleostomi_PTN000841435 participates in folic acid transport (GO:0015884) 
20150909: Euteleostomi_PTN000841435 participates in methotrexate transport (GO:0051958) 
20150909: Euteleostomi_PTN000743341 participates in thiamine transmembrane transport (GO:0071934) 

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED

# NOTES

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).