# HISTORY 07 May 2016: Updated by: TOUCHUP-v1.18 14 Mar 2016: Updated by: TOUCHUP-v1.12 24 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function 20150916: Eukaryota_PTN000069920 has function endopeptidase activator activity (GO:0061133) # cellular_component 20150916: Eukaryota_PTN000069920 is found in proteasome complex (GO:0000502) 20150916: Eukaryota_PTN000069920 is found in cytoplasm (GO:0005737) # biological_process 20150916: Eukaryota_PTN000069920 participates in regulation of proteasomal protein catabolic process (GO:0061136) 20150916: Eukaryota_PTN000069920 participates in regulation of G1/S transition of mitotic cell cycle (GO:2000045) 20150916: Eukaryota_PTN000069920 participates in positive regulation of endopeptidase activity (GO:0010950) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).