# HISTORY
24 Mar 2016: Updated by: TOUCHUP-v1.15
14 Mar 2016: Updated by: TOUCHUP-v1.12

# molecular_function
20150306: root_PTN000068227 has function RNA-DNA hybrid ribonuclease activity (GO:0004523) 

# cellular_component

# biological_process
20150306: root_PTN000068227 participates in DNA replication, removal of RNA primer (GO:0043137) 
# PRUNED

24 Mar 2016: Bilateria_PTN001319615 has been pruned from tree

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED

# NOTES
14 Mar 2016: Bilateria_PTN001319615 has been pruned from tree
The process term "termination of RNA polymerase II transcription" may not be used correctly. In the cited reference, it shows that a DNA-RNA hybrid creates a pause site to stop the transcription, while RNase H removes the RNA in the hybrid, and thus promotes the read through. This result is shown in the Figure 3 of the paper. One can argue that RNase H is involved in the termination process, but in a negative way. A dispute was sent to protein2go.
6-March-2015, HM

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).