# HISTORY 07 May 2016: Updated by: TOUCHUP-v1.18 14 Mar 2016: Updated by: TOUCHUP-v1.12 24 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function 20150820: Eukaryota_PTN000056988 contributes to function translation initiation factor activity (GO:0003743) 20150820: Eukaryota_PTN000056988 has function translation initiation factor binding (GO:0031369) # cellular_component 20150820: Eukaryota_PTN000056988 is found in eukaryotic translation initiation factor 3 complex, eIF3m (GO:0071541) 20150820: Eukaryota_PTN000057105 is found in COP9 signalosome (GO:0008180) 20150820: Eukaryota_PTN000057040 is found in proteasome complex (GO:0000502) # biological_process 20150820: Eukaryota_PTN000056988 participates in translational initiation (GO:0006413) 20150820: Eukaryota_PTN000057105 participates in cullin deneddylation (GO:0010388) 20150820: Eukaryota_PTN000057040 participates in proteasome-mediated ubiquitin-dependent protein catabolic process (GO:0043161) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).