# HISTORY
24 Mar 2016: Updated by: TOUCHUP-v1.15
14 Mar 2016: Updated by: TOUCHUP-v1.12

# molecular_function
20140826: Eukaryota_PTN000053416 has function chromatin binding (GO:0003682) 
20140826: Eukaryota_PTN000053416 has function 3'-5' DNA helicase activity (GO:0043138) 
20140826: Eukaryota_PTN000053416 has function DNA replication origin binding (GO:0003688) 
20140826: Eukaryota_PTN000053416 has function single-stranded DNA binding (GO:0003697) 

# cellular_component
20140826: Eukaryota_PTN000053416 is found in DNA replication preinitiation complex (GO:0031261) 
20140826: Eukaryota_PTN000053416 is found in nuclear pre-replicative complex (GO:0005656) 
20140826: Eukaryota_PTN000053416 is found in replication fork protection complex (GO:0031298) 

# biological_process
20140826: Eukaryota_PTN000053416 participates in mitotic DNA replication preinitiation complex assembly (GO:1902977) 
20140826: Eukaryota_PTN000053416 participates in pre-replicative complex assembly involved in nuclear cell cycle DNA replication (GO:0006267) 
20140826: Eukaryota_PTN000053416 participates in double-strand break repair via break-induced replication (GO:0000727) 
20140826: Eukaryota_PTN000053416 participates in DNA replication initiation (GO:0006270) 
20140826: Eukaryota_PTN000053416 participates in positive regulation of G1/S transition of mitotic cell cycle (GO:1900087) 
20140826: Eukaryota_PTN000053416 participates in regulation of chromatin silencing at telomere (GO:0031938) 

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED

# NOTES

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).