# HISTORY 12 Jan 2017: Saved by mfeuerma using Paint 2.28 on 12 Jan 2017 using PANTHER version UPL 11.0 # molecular_function 20170112: root_PTN000046094 contributes to function cytochrome-c oxidase activity (GO:0004129) 20170112: Bacteria _PTN002234665 has LOST/MODIFIED function cytochrome-c oxidase activity (GO:0004129) 20170112: Bacteria _PTN002234665 has function cytochrome bo3 ubiquinol oxidase activity (GO:0009486) # cellular_component 20170112: Bacteria _PTN002234665 is found in integral component of plasma membrane (GO:0005887) 20170112: Eukaryota_PTN000046096 is found in mitochondrial respiratory chain complex IV (GO:0005751) # biological_process 20170112: root_PTN000046094 participates in respiratory electron transport chain (GO:0022904) 20170112: Eukaryota_PTN000046096 participates in mitochondrial electron transport, cytochrome c to oxygen (GO:0006123) 20170112: root_PTN000046094 participates in aerobic respiration (GO:0009060) 20170112: root_PTN000046094 participates in electron transport coupled proton transport (GO:0015990) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).