# HISTORY
07 May 2016: Updated by: TOUCHUP-v1.18
14 Mar 2016: Updated by: TOUCHUP-v1.12
23 Mar 2016: Updated by: TOUCHUP-v1.15

# molecular_function
20140731: Euteleostomi_PTN000008570 has function interleukin-1 receptor binding (GO:0005149) 
20140731: Euteleostomi_PTN000008570 has function cytokine activity (GO:0005125) 

# cellular_component
20140731: Euteleostomi_PTN000008570 is found in extracellular space (GO:0005615) 

# biological_process
20140731: Euteleostomi_PTN000008570 participates in cytokine-mediated signaling pathway (GO:0019221) 
20140731: Mammalia_PTN000008680 participates in positive regulation of I-kappaB kinase/NF-kappaB signaling (GO:0043123) 
20140731: Mammalia_PTN000008680 participates in positive regulation of JNK cascade (GO:0046330) 

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED

# NOTES
This one is to be finished
July 31, 2014, HM

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).