# HISTORY 23 Mar 2016: Updated by: TOUCHUP-v1.15 14 Mar 2016: Updated by: TOUCHUP-v1.12 # molecular_function 20150708: root_PTN000007991 has function 2 iron, 2 sulfur cluster binding (GO:0051537) 20150708: root_PTN000007991 has function ferrous iron binding (GO:0008198) 20150708: root_PTN000007991 has function 4 iron, 4 sulfur cluster binding (GO:0051539) # cellular_component 20150708: root_PTN000007991 is found in mitochondrial matrix (GO:0005759) 20150708: Bacteria _PTN001601122 is found in cytosol (GO:0005829) 20150708: Actinomycetales_PTN000801277 is found in plasma membrane (GO:0005886) 20150708: node_PTN001601168 is found in cytosol (GO:0005829) 20150708: Bacteria _PTN001601122 is NOT found in mitochondrial matrix (GO:0005759) 20150708: Cyanobacteria_PTN001601088 is NOT found in mitochondrial matrix (GO:0005759) 20150708: Bacteria _PTN000008127 is NOT found in mitochondrial matrix (GO:0005759) # biological_process 20150708: root_PTN000007991 participates in sulfur compound metabolic process (GO:0006790) 20150708: root_PTN000007991 participates in protein maturation by iron-sulfur cluster transfer (GO:0097428) 20150708: root_PTN000007991 participates in iron-sulfur cluster assembly (GO:0016226) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).