# HISTORY 07 May 2016: Updated by: TOUCHUP-v1.18 14 Mar 2016: Updated by: TOUCHUP-v1.12 23 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function 20140521: node_PTN000006754 has function deoxyribonuclease activity (GO:0004536) # cellular_component # biological_process 20140521: node_PTN000006754 participates in DNA catabolic process (GO:0006308) # PRUNED 07 May 2016: node_PTN000800325 has been pruned from tree # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES 23 Mar 2016: node_PTN000800325 has been pruned from tree 14 Mar 2016: node_PTN000800325 has been pruned from tree There is an early duplication event at the root of this family, giving rise to a small distant clade of bacteria, which was pruned, and all other sequences. MF: - deoxyribonuclease activity (GO:0004536) in PTN000006754 CC: There are annotations to nucleus, cytoplasm, and mitochondria across the entire tree, and some bacterial sequences are present in the tree. Propagated 'intracellular organelle', and put a stop propagation on the bacterial sequences. Reviewed annotation 2014-05-21 PG # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).