# HISTORY 15 Sep 2016: Saved by mfeuerma using Paint 2.22 # molecular_function 20160915: Tetrapoda_PTN000004954 has function structural constituent of tooth enamel (GO:0030345) # cellular_component 20160915: Tetrapoda_PTN000004954 is found in extracellular matrix (GO:0031012) 20160915: Tetrapoda_PTN000004954 is found in proteinaceous extracellular matrix (GO:0005578) 20160915: Ascomycota_PTN000004981 is found in eisosome (GO:0032126) 20160915: Ascomycota_PTN000004981 is found in cytoplasm (GO:0005737) # biological_process 20160915: Tetrapoda_PTN000004954 participates in tooth mineralization (GO:0034505) 20160915: Ascomycota_PTN000004981 participates in eisosome assembly (GO:0070941) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES MAF: i would split the tree, with fungal protein in one tree and animal proteins in another. # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).