Recruitment of TRAF3 to IPS-1
type: GO_0003674
BFO_0000050: TRAF3-dependent IRF activation pathway
directly activates: TBK1/IKK epsilon complex interacts with IPS-1 bound TRAF3

TBK1/IKK epsilon complex interacts with IPS-1 bound TRAF3
type: GO_0003674
BFO_0000050: TRAF3-dependent IRF activation pathway
directly activates: Recruitment of IRF3/7Â

Recruitment of IRF3/7Â
type: GO_0003674
BFO_0000050: TRAF3-dependent IRF activation pathway
directly activates: Phosphorylation and release of IRF3/IRF7
directly activates: Catalysis402

Phosphorylation and release of IRF3/IRF7
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005741
type: GO_0004672
BFO_0000050: TRAF3-dependent IRF activation pathway
directly activates: Dimerization of Phospho IRF3 or phospho IRF7
directly activates: BiochemicalReaction930

Dimerization of Phospho IRF3 or phospho IRF7
type: GO_0003674
BFO_0000050: TRAF3-dependent IRF activation pathway
directly activates: Translocation of phosphorylated IRF3/7 dimers into nucleus

Translocation of phosphorylated IRF3/7 dimers into nucleus
type: GO_0003674
BFO_0000050: TRAF3-dependent IRF activation pathway

Interaction of CBP/p300 with p-IRF3 dimer
type: GO_0003674
BFO_0000050: TRAF3-dependent IRF activation pathway

IRF3:CBP/p300 complex binds the promoters of IFN-beta
type: GO_0003674
BFO_0000050: TRAF3-dependent IRF activation pathway

TRAF3-dependent IRF activation pathway
type: GO_0008150

Expression of IFN-beta
type: GO_0003674
BFO_0000050: TRAF3-dependent IRF activation pathway