ASMT
label: UniProt:P46597 ASMT

AANAT
label: SNAT
label: UniProt:Q16613 AANAT

Tryptophan is hydroxylated
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004510
BFO_0000050: Serotonin and melatonin biosynthesis
directly activates: Decarboxylation of 5-hydroxytryptophan forms serotonin
directly activates: Catalysis2942

Decarboxylation of 5-hydroxytryptophan forms serotonin
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004058
BFO_0000050: Serotonin and melatonin biosynthesis
directly activates: BiochemicalReaction3682
directly activates: N-acetylation of serotonin
directly activates: Catalysis1640
directly activates: Catalysis2943

N-acetylation of serotonin
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: enabled by
  some values from: AANAT
type: GO_0004059
BFO_0000050: Serotonin and melatonin biosynthesis
directly activates: Methylation of N-acetyl-5-HT to form melatonin
directly activates: Catalysis2944

Methylation of N-acetyl-5-HT to form melatonin
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: enabled by
  some values from: ASMT
type: GO_0008172
BFO_0000050: Serotonin and melatonin biosynthesis

Serotonin and melatonin biosynthesis
type: GO_0008150