CNT1
SLC28A1
UniProt:O00337 SLC28A1
ACATN
AT1
SLC33A1
UniProt:O00400 SLC33A1
COPT1
CTR1
SLC31A1
UniProt:O15431 SLC31A1
G6PT
G6PT1
PRO0685
SLC37A4
TRG19
UniProt:O43826 SLC37A4
CNT2
SLC28A2
UniProt:O43868 SLC28A2
LAT3
PB39
POV1
SLC43A1
UniProt:O75387 SLC43A1
EMTH
OCT3
SLC22A3
UniProt:O75751 SLC22A3
KIAA0880
OATP2B1
OATPB
SLC21A9
SLCO2B1
UniProt:O94956 SLCO2B1
GLUT5
SLC2A5
UniProt:P22732 SLC2A5
NAT1
NET1
SLC6A2
SLC6A5
UniProt:P23975 SLC6A2
ATRC1
ERR
REC1L
SLC7A1
UniProt:P30825 SLC7A1
SGLT2
SLC5A2
UniProt:P31639 SLC5A2
SLC6A6
UniProt:P31641 SLC6A6
G6PC
UniProt:P35575 G6PC
ASCT1
SATT
SLC1A4
UniProt:P43007 SLC1A4
OATP
OATP1
OATP1A2
SLC21A3
SLCO1A2
UniProt:P46721 SLCO1A2
SLC6A12
UniProt:P48065 SLC6A12
LSH
NRAMP
NRAMP1
SLC11A1
UniProt:P49279 SLC11A1
DCT1
DMT1
NRAMP2
OK/SW-cl.20
SLC11A2
UniProt:P49281 SLC11A2
ATRC2
CAT2
SLC7A2
UniProt:P52569-1 SLC7A2
UniProt:P52569-2 SLC7A2
SLC5A3
UniProt:P53794 SLC5A3
SLC12A3
TSC
UniProt:P55017 SLC12A3
SLC35A2
UGALT
UGT
UGTL
UniProt:P78381 SLC35A2
SLC35A1
UniProt:P78382 SLC35A1
DAT1
SLC6A3
UniProt:Q01959 SLC6A3
RH50
RHAG
UniProt:Q02094 RHAG
NADC1
SDCT1
SLC13A2
UniProt:Q13183 SLC13A2
DER12
ENT2
HNP36
SLC29A2
UniProt:Q14542 SLC29A2
NPT1
SLC17A1
UniProt:Q14916 SLC17A1
ASCT2
M7V1
RDR
RDRC
SLC1A5
UniProt:Q15758 SLC1A5
SGLT4
SLC5A9
UniProt:Q2M3M2 SLC5A9
SLC10A6
SOAT
UniProt:Q3KNW5 SLC10A6
PAT2
SLC36A2
TRAMD1
UniProt:Q495M3 SLC36A2
B0AT1
SLC6A19
UniProt:Q695T7 SLC6A19
NCKX6
NCLX
SLC24A6
UniProt:Q6J4K2 SLC24A6
SLC30A6
UniProt:Q6NXT4 SLC30A6
ZNT6
SLC39A5
UniProt:Q6ZMH5 SLC39A5
ZIP5
OATP4C1
OATPX
SLC21A20
SLCO4C1
UniProt:Q6ZQN7 SLCO4C1
HFRC
SLC35D2
UGTREL8
UniProt:Q76EJ3 SLC35D2
ENT4
PMAT
PSEC0113
SLC29A4
UniProt:Q7RTT9 SLC29A4
PAT1
SLC36A1
UniProt:Q7Z2H8 SLC36A1
NACT
SLC13A5
UniProt:Q86YT5 SLC13A5
NHE9
SLC9A9
UniProt:Q8IVB4 SLC9A9
SLC30A8
UniProt:Q8IWU4 SLC30A8
ZNT8
NPT2C
NPTIIC
SLC34A3
UniProt:Q8N130 SLC34A3
LAT4
PP7664
SLC43A2
UniProt:Q8N370 SLC43A2
AIT
SLC5A8
SMCT
SMCT1
UniProt:Q8N695 SLC5A8
SLC30A7
UniProt:Q8NEW0 SLC30A7
ZNT7
ZNTL2
SLC30A5
UniProt:Q8TAD4 SLC30A5
ZNT5
ZNTL1
ZTL1
MCT10
SLC16A10
TAT1
UniProt:Q8TF71 SLC16A10
JM24
PP7194
SLC38A5
SN2
SNAT5
UniProt:Q8WUX1 SLC38A5
NADC3
SDCT2
SLC13A3
UniProt:Q8WWT9 SLC13A3
KST1
SLC5A11
SLGTX
SMIT2
UniProt:Q8WWX8 SLC5A11
ATRC3
CAT3
SLC7A3
UniProt:Q8WY07 SLC7A3
HKE4
RING5
SLC39A7
UniProt:Q92504 SLC39A7
KIAA0267
NHE6
SLC9A6
UniProt:Q92581 SLC9A6
NIS
SLC5A5
UniProt:Q92911 SLC5A5
OATP2A1
SLC21A2
SLCO2A1
UniProt:Q92959 SLCO2A1
ATA3
NAT3
SLC38A4
SNAT4
UniProt:Q969I6 SLC38A4
PSEC0055
SLC35B4
UniProt:Q969S0 SLC35B4
YEA4
FUCT1
SLC35C1
UniProt:Q96A29 SLC35C1
BWR1A
BWSCR1A
HET
IMPT1
ITM
ORCTL2
SLC22A18
SLC22A1L
TSSC5
UniProt:Q96BI1 SLC22A18
SLC6A18
UniProt:Q96N87 SLC6A18
XTRP2
ATA2
KIAA1382
SAT2
SLC38A2
SNAT2
UniProt:Q96QD8 SLC38A2
SLC2A13
UniProt:Q96QE2 SLC2A13
OATL4
SLC22A12
URAT1
UniProt:Q96S37 SLC22A12
G17
SLC38A3
SN1
SNAT3
UniProt:Q99624 SLC38A3
SLC30A3
UniProt:Q99726 SLC30A3
ZNT3
ENT1
SLC29A1
UniProt:Q99808 SLC29A1
PROT
SLC6A7
UniProt:Q99884 SLC6A7
SLC30A2
UniProt:Q9BRI3 SLC30A2
ZNT2
G6PC3
UGRP
UniProt:Q9BUM1 G6PC3
ENT3
SLC29A3
UniProt:Q9BZD2 SLC29A3
NAS1
NASI1
SLC13A1
UniProt:Q9BZW2 SLC13A1
BIGM103
PP3105
SLC39A8
UniProt:Q9C0K1 SLC39A8
ZIP8
CHT1
SLC5A7
UniProt:Q9GZV3 SLC5A7
ETT
OCTN1
SLC22A4
UT2H
UniProt:Q9H015 SLC22A4
ATA1
NAT2
SAT1
SLC38A1
SNAT1
UniProt:Q9H2H9 SLC38A1
B0AT2
NTT73
SBAT1
SLC6A15
UniProt:Q9H2J7 SLC6A15
RHBG
UniProt:Q9H310 RHBG
SLC32A1
UniProt:Q9H598 SLC32A1
VGAT
VIAAT
CNT3
SLC28A3
UniProt:Q9HAS3 SLC28A3
SIT1
SLC6A20
UniProt:Q9NP91 SLC6A20
XT3
XTRP3
LST2
OATP1B3
OATP8,SLC21A8
SLCO1B3
UniProt:Q9NPD5 SLCO1B3
G6PC2
IGRP
UniProt:Q9NQR9 G6PC2
SLC17A5
UniProt:Q9NRA2 SLC17A5
GLUT9
SLC2A9
UniProt:Q9NRM0 SLC2A9
C15orf6
CDRC2
PDRC2
RHCG
RHGK
UniProt:Q9UBD6 RHCG
DIC
SLC25A10
UniProt:Q9UBX3 SLC25A10
OATP3A1
OATPD
SLC21A11
SLCO3A1
UniProt:Q9UIG8-1 SLCO3A1
SLC13A4
SUT1
UniProt:Q9UKG4 SLC13A4
KIAA1265
SLC39A10
UniProt:Q9ULF5 SLC39A10
ZIP10
SLC6A14
UniProt:Q9UN76 SLC6A14
SLC5A6
SMVT
UniProt:Q9Y289 SLC5A6
SLC35A3
UniProt:Q9Y2D2 SLC35A3
LST1
OATP1B1
OATP2
OATPC
SLC21A6
SLCO1B1
UniProt:Q9Y6L6 SLCO1B1
SLC30A1
UniProt:Q9Y6M5 SLC30A1
ZNT1
Cl-/HCO3- exchanger transport
Na+-coupled HCO3- cotransport
Na+-driven Cl-/HCO3- exchanger transport
Na+/Ca2+ exchanger transport
K+-dependent Na+/Ca2+ exchanger transport
K+-independent Li+/Ca2+ exchanger transport
Na+/H+ exchanger transport (at cell membrane)
Na+/H+ exchanger transport (at early endosome membrane)
Na+/H+ exchanger transport (at trans-golgi membrane)
Na+/H+ exchanger transport (at late endosome membrane)
Na+/Cl- cotransport
Na+, K+/2Cl- cotransport
K+/Cl- cotransport
SLC26A1,2 transport extracellular SO4(2-) to cytosol
Group 2 - Cl-/HCO3- exchanger transport
Group 3 - Selective Cl- transport
Electrogenic Na+/Pi cotransport
Electroneutral Na+/Pi cotransport
Type III Na+/Pi cotransport
SLC16A10-mediated uptake of aromatic amino acids
SLC38A1 (ATA1)-mediated uptake of neutral amino acids
SLC38A2 (ATA2)-mediated uptake of neutral amino acids
SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine
SLC38A4 (ATA3)-mediated uptake of arginine and lysine
SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine
SLC43A1 (LAT3)-mediated uptake of large neutral amino acids
SLC43A2 (LAT4)-mediated uptake of large neutral amino acids
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine
SLC6A15-mediated amino acid uptake
SLC6A18-mediated glycine uptake
SLC6A20-mediated uptake of proline
SLC6A6-mediated uptake of taurine and beta-alanine
SLC7A5-mediated uptake of neutral amino acids
SLC7A8-mediated uptake of neutral amino acids
SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine
SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine
SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine
SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine
SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane
SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane
SLC36A1-mediated uptake of glycine, proline, and alanine
SLC36A2-mediated uptake of glycine and proline
SLC6A14-mediated uptake of basic and neutral amino acids and of beta-alanine
SLC6A19-mediated uptake of neutral amino acids
SLC7A1 (CAT-1)-mediated uptake of cationic amino acids
SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids
SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids
SLC7A3 (CAT-3)-mediated uptake of cationic amino acids
SLC7A10-mediated uptake of small neutral amino acids
SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate
SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine
SLC7A7 (y+LAT1)-mediated exchange of extracellular leucine for cytosolic arginine
SLC7A9-mediated exchange of extracellular arginine, lysine, or cystine for cytosolic leucine
Glutamate transport
Vesicular glutamate transport
Proton-coupled sialic acid co-transport
Type I Na+-coupled phosphate co-transport
Na+/I- cotransport (influx) by the Na+/I- symporter
Passive I- efflux mediated by SMCT1
Na+-dependent monocarboxylate transport by SMCT
Sulfate is exported to the cytosol in exchange for dicarboxylate
malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix]
Proton-coupled di- and tri-peptide cotransport
Proton-coupled histidine and di-peptide cotransport
Vesicular inhibitory amino acid transport
Transport (influx) of fructose by GLUT5
extracellular fructose => cytosolic fructose
Transport (influx) of glucose, galactose, and sodium ions by SGLT1
Transport (efflux) of fructose, galactose, and glucose by GLUT2
cytosolic fructose, galactose, or glucose => extracellular fructose, galactose, or glucose
Glucose is taken up across the plasma membrane by a glucose transport protein (GLUT)
alpha-D-glucose (extracellular) <=> alpha-D-glucose (cytosol)
Glucose is secreted across the plasma membrane
alpha-D-glucose (cytosol) <=> alpha-D-glucose (extracellular)
GLUT1 + ATP <=> GLUT1:ATP
GLUT1:ATP <=> GLUT1 + ATP
alpha-D-Glucose + ATP => alpha-D-glucose 6-phosphate + ADP
glucokinase (GCK1) + glucokinase regulatory protein (GKRP) <=> GCK1:GKRP complex
cytosolic GCK1:GKRP complex <=> glucokinase (GCK1) + glucokinase regulatory protein (GKRP)
GCK1:GKRP [cytosol] => GCK1:GKRP [nucleoplasm]
Transport of glucokinase (GCK1):GKRP complex to the nucleus
Dissociation of the nucleoplasmic GCK1:GKRP complex
nucleoplasmic GCK1:GKRP complex => glucokinase (GCK1) + glucokinase regulatory protein (GKRP)
glucokinase [nucleoplasm] => glucokinase [cytosol]
Cytosolic glucose 6-phosphate is exchanged for orthophosphate from the endoplasmic reticulum lumen by SLC37A4
alpha-D-glucose 6-phosphate (cytosol) + orthophosphate (ER lumen) => alpha-D-glucose 6-phosphate (ER lumen) + orthophosphate (cytosol) (SLC37A4)
G6PC hydrolyzes glucose 6-phosphate to form glucose and orthophosphate (liver)
alpha-D-Glucose 6-phosphate + H2O => alpha-D-Glucose + Orthophosphate (G6PC - liver)
G6PC2 hydrolyzes glucose 6-phosphate to form glucose and orthophosphate (islet)
alpha-D-Glucose 6-phosphate + H2O => alpha-D-Glucose + Orthophosphate (G6PC2 - islet)
G6PC3 hydrolyzes glucose 6-phosphate to form glucose and orthophosphate (ubiquitous)
alpha-D-Glucose 6-phosphate + H2O => alpha-D-Glucose + Orthophosphate (G6PC3 - ubiquitous)
Efflux of glucose from the endoplasmic reticulum
Glucose transport by class I GLUTs
GLUT7 and GLUT11 transport glucose and fructose
GLUT9 transports glucose, fructose and urate
Glucose transport by class III GLUTs
Co-transport (influx) of glucose and Na+ ions by SGLT2
Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4
Co-transport (influx) of myo-inositol and two Na+ ions by SMIT
Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6
HMIT co-transports myo-inositol with a proton
NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages
DCT1 (NRAMP2) mediates divalent iron uptake across the apical membrane of enterocytes
Ferroportin mediates iron influx across the basolateral membrane of enterocytes
Ferroportin mediates iron efflux on macrophages
ZnT1 mediates the efflux of zinc from the cell
ZnT2 facilitates zinc vesicular sequestration
ZnT3 transports zinc into synaptic vesicles
ZnT5 transports zinc into secretory granules in pancreatic beta cells
ZnT6 transports zinc into the golgi apparatus
ZnT7 transports zinc into the golgi apparatus
ZnT8 transports zinc into the secretory vesicles of pancreatic beta cells specifically
hZIP1-4 mediate zinc uptake by cells
hZIP5 mediates zinc uptake by cells
ZIP6 and ZIP14 mediate zinc influx into cells
ZIP7 mediates zinc efflux from the endoplasmic reticulum
ZIP8 mediates zinc influx into cells
hZIP10 mediates zinc influx into cells
Cellular copper transport is mediated by human copper transporter 1 hCTR1
MagT transporters mediate magnesium uptake into cells
GAT1-3 mediate Na+/Cl- dependent GABA transport
Uptake of Noradrenaline
NAT1 mediates norepinephrine uptake
Reuptake of dopamine from the synaptic celft into neurons
Reuptake of dopamine from the synaptic cleft into neurons
Reuptake of serotonin from the synapse
GLYT1/2 mediate glycine uptake
PROT mediates L-proline uptake
VMAT1/2 can mediate the transport of biogenic amines
Sodium- and chloride-dependent choline transport by CHT
HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively
RhAG mediates ammounium export from red blood cells
RhBG mediates ammonium effflux out of kidney collecting duct cells
RhBG mediates ammonium influx into kidney collecting duct cells
RhCG mediates ammonium influx into kidney collecting duct cells
RhCG mediates ammonium efflux out of kidney collecting duct cells
CTL1-5 can mediate the uptake of choline
Cho transports from the extracellular space to the cytosol
OCT1 transports organic cations into hepatic cells
OCT1 transports organic cations out of hepatic cells
OCT2 mediates tubular uptake of organic cations in the kidney
OCT2 mediates tubular secretion of organic cations in the kidney
OCT3 mediates renal clearance of organic cations
OCT3 mediates renal uptake of organic cations
OCT4 mediates transport of ergothioneine
Carnitine transporters mediates sodium-dependent uptake of carnitine
ORCTL2 mediates the transport of chloroquine and quinidine with efflux of protons
OAT1-3 transport organic anions with antiport of dicarboxylic acids
OAT2 and OAT4 mediate transport of sulphate conjugates
URAT1 regulates urate levels in blood with exchange for organic anions
Na+-dependent multivitamin transporter
Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1
Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3
Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2
Equilibrative transport (export) of nucleosides and adenine by solute carrier family 29 (nucleoside transporters), member 3
Equilibrative transport (import) of nucleosides and adenine by solute carrier family 29 (nucleoside transporters), member 3
Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4
Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4
AT1 transports acetyl-CoA into the Golgi lumen
SLC35A1 mediates the antiport of CMP-sialic acid in exchange for CMP
SLC35A2 mediates the antiport of UDP-Gal and UDP-GalNAc in exchange for UMP
SLC35A3 mediates the antiport of UDP-GlcNAc in exchange for UMP
SLC35B2,3 transport cytosolic PAPS to Golgi lumen
SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen
SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen
SLC35C1 mediates the transport of UDP-fucose into the Golgi lumen
UDP-glucuronate transport from the cytosol to ER lumen
SLC35D2 exchanges UDP-sugars for UMP
SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP
FATP1, 4 and 6 can mediate the influx of long chain fatty acids into cells
Transport (influx) of bile salts and acids by OATP-A
Transport (influx) of glycocholate and taurocholate by OATP-8
Transport (influx) of glycocholate and taurocholate by OATP-C
SLCO1B1, SLCO4A1 and SLCO1C1 mediate the transport of thyroid hormones
PGT transports prostaglandins
SLCO2B1 has a narrow substrate specificity
SLCO3A1 isoform 1 has abroad substrate specificity
SLCO4C1 mediates the transport of digoxin
SOAT can transport taurolithocholate-3-sulphate
NaS1 co-transports sulphate and a sodium ion
NaS2 co-transports sulphate and two sodium ions
NaDC1 co-transports dicarboxylic acids and a sodium ion
NaDC3 co-transports the dicarboxylic acid succinate and three sodium ion
NACT co-transports trivalent citrate and a sodium ion
MATEs mediate extrusion of xenobiotics
MCTs mediate proton-coupled transport of monocarboxylates and ketone bodies
SLC-mediated transmembrane transport
Transport of inorganic cations/anions and amino acids/oligopeptides
Bicarbonate transporters
Sodium/Calcium exchangers
Sodium/Proton exchangers
Cation-coupled Chloride cotransporters
Multifunctional anion exchangers
Sodium-coupled phosphate cotransporters
Type II Na+/Pi cotransporters
Amino acid transport across the plasma membrane
Organic anion transporters
Proton-coupled neutral amino acid transporters
Proton/oligonucleotide cotransporters
Hexose transport
Hexose uptake
Glucose transport
Regulation of Glucokinase by Glucokinase Regulatory Protein
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
Facilitative Na+-independent glucose transporters
Class II GLUTs
Na+-dependent glucose transporters
Inositol transporters
Metal ion SLC transporters
Zinc transporters
Zinc efflux and compartmentalization by the SLC30 family
Zinc influx into cells by the SLC39 gene family
Na+/Cl- dependent neurotransmitter transporters
Rhesus glycoproteins mediate ammonium transport.
Organic cation/anion/zwitterion transport
Organic cation transport
Organic anion transport
Transport of vitamins, nucleosides, and related molecules
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane
Transport of nucleotide sugars
Transport of fatty acids
Transport of organic anions
Sodium-coupled sulphate, di- and tri-carboxylate transporters
Proton-coupled monocarboxylate transport