LIG4
UniProt:P49917 LIG4
HYRC
HYRC1
PRKDC
UniProt:P78527 PRKDC
Association of Ku heterodimer with ends of DNA double-strand break
Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks
Autophosphorylation of DNA-PKcs
Synapsis, or interaction between two DNA-PK:DNA complexes at opposing ends of DNA DSB
Removal of 3'-phosphoglycolate (PG) moiety from DSB ends
Removal of 3'-phosphate moiety from DSB ends
Association of the XRCC4:DNA ligase IV complex with the DNA-PK:DNA synaptic complex
Removal of repair proteins and ligation of the processed ends of the DNA double-strand break
Nonhomologous End-joining (NHEJ)
Processing of DNA ends prior to end rejoining