NAMPT
label: PBEF
label: PBEF1
label: UniProt:P43490 NAMPT

QPRT
label: UniProt:Q15274 QPRT

2-amino 3-carboxymuconate semialdehyde transforms non-enzymatically to quinolinate
type: GO_0003674
BFO_0000050: Nicotinate metabolism
directly activates: A phospho-ribosyl group is added to quinolinate
directly activates: Catalysis2786

A phospho-ribosyl group is added to quinolinate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: enabled by
  some values from: QPRT
type: GO_0004514
BFO_0000050: Nicotinate metabolism
directly activates: Nicotinate D-ribonucleotide + ATP => deamino-NAD+ + pyrophosphate [NMNAT1]
directly activates: Nicotinate D-ribonucleotide + ATP => deamino-NAD+ + pyrophosphate [NMNAT2]
directly activates: Nicotinate D-ribonucleotide + ATP => deamino-NAD+ + pyrophosphate [NMNAT3]
directly activates: Catalysis2787
directly activates: Catalysis2788
directly activates: Catalysis2789

Nicotinate D-ribonucleotide + ATP => deamino-NAD+ + pyrophosphate [NMNAT1]
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005654
type: GO_0000309
BFO_0000050: Nicotinate metabolism
directly activates: Amidation of deamino-NAD+ to NAD+
directly activates: Catalysis2790

Nicotinate D-ribonucleotide + ATP => deamino-NAD+ + pyrophosphate [NMNAT2]
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0000309
BFO_0000050: Nicotinate metabolism
directly activates: Amidation of deamino-NAD+ to NAD+
directly activates: Catalysis2790

Nicotinate D-ribonucleotide + ATP => deamino-NAD+ + pyrophosphate [NMNAT3]
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0000309
BFO_0000050: Nicotinate metabolism
directly activates: Amidation of deamino-NAD+ to NAD+
directly activates: Catalysis2790

Amidation of deamino-NAD+ to NAD+
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0003952
BFO_0000050: Nicotinate metabolism
directly activates: NAD+ is phosphorylated to NADP+
directly activates: Catalysis2791

NAD+ is phosphorylated to NADP+
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0003951
BFO_0000050: Nicotinate metabolism

Deamination of nicotinamide to nicotinate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0008936
BFO_0000050: Nicotinamide salvaging
directly activates: A phosphoribosyl group is added to nicotinate to form nicotinate mononucleotide (NaMN)
directly activates: Catalysis2794
directly activates: Control476

Condensation of nicotinamide to nicotinamide D-ribonucleotide (NMN)
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: enabled by
  some values from: NAMPT
type: Restriction
  on property: enabled by
  some values from: NAMPT
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0047280
BFO_0000050: Nicotinamide salvaging
directly activates: Nicotinate D-ribonucleotide + ATP => deamino-NAD+ + pyrophosphate [NMNAT1]
directly activates: Nicotinate D-ribonucleotide + ATP => deamino-NAD+ + pyrophosphate [NMNAT2]
directly activates: Nicotinate D-ribonucleotide + ATP => deamino-NAD+ + pyrophosphate [NMNAT3]
directly activates: Catalysis2787
directly activates: Catalysis2788
directly activates: Catalysis2789

A phosphoribosyl group is added to nicotinate to form nicotinate mononucleotide (NaMN)
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004516
BFO_0000050: Nicotinamide salvaging

Nicotinate metabolism
type: GO_0008150

Nicotinamide salvaging
type: GO_0008150
BFO_0000050: Nicotinate metabolism