NAMPT
PBEF
PBEF1
UniProt:P43490 NAMPT
QPRT
UniProt:Q15274 QPRT
2-amino 3-carboxymuconate semialdehyde transforms non-enzymatically to quinolinate
A phospho-ribosyl group is added to quinolinate
Nicotinate D-ribonucleotide + ATP => deamino-NAD+ + pyrophosphate [NMNAT1]
Nicotinate D-ribonucleotide + ATP => deamino-NAD+ + pyrophosphate [NMNAT2]
Nicotinate D-ribonucleotide + ATP => deamino-NAD+ + pyrophosphate [NMNAT3]
Amidation of deamino-NAD+ to NAD+
NAD+ is phosphorylated to NADP+
Deamination of nicotinamide to nicotinate
Condensation of nicotinamide to nicotinamide D-ribonucleotide (NMN)
A phosphoribosyl group is added to nicotinate to form nicotinate mononucleotide (NaMN)
Nicotinate metabolism
Nicotinamide salvaging