CHAT
UniProt:P28329 CHAT
SLC6A12
UniProt:P48065 SLC6A12
ALDH5A1
SSADH
UniProt:P51649 ALDH5A1
SLC18A2
SVMT
UniProt:Q05940 SLC18A2
VMAT2
SLC18A3
UniProt:Q16572 SLC18A3
VACHT
ATA2
KIAA1382
SAT2
SLC38A2
SNAT2
UniProt:Q96QD8 SLC38A2
CHT1
SLC5A7
UniProt:Q9GZV3 SLC5A7
SLC32A1
UniProt:Q9H598 SLC32A1
VGAT
VIAAT
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine
GAT1-3 mediate Na+/Cl- dependent GABA transport
Uptake of Noradrenaline
Re-acidification of clathrin sculpted monoamine tranport vesicle lumen
Loading of dopamine into synaptic veiscles
Noradrenalin synaptic vesicle docking and priming
Release of noradrenaline at the synapse
Metabolism of Noradrenaline
loading of Serotonin in synaptic vesicles
Serotonin loaded synaptic vesicle docking and priming
Release of docked serotonin loaded synaptic vesicle
L-Glutamine transport into neurons
Transport of L-Glutamine (cytosol) to mitochondrial matrix
glutamine + H2O => glutamate + NH4+ [GLS]
Tranport of L-Glutamate (mitochondrial matrix) to cytosol
L-Glutamate loading of synaptic vesicle
Glutamate synaptic vesicle docking and priming
release of L-Glutamate at the synapse
L-Glutamate uptake by neurons
Dopamine synaptic vesicle docking and priming
Release of docked dopamine loaded synaptic vesicle
Transport of Choline
Cho is acetylated to AcCho by CHAT
Synthesis of o-acetylcholine
Re-acidification of the clathrin sculpted acetylcholine transport vesicle
Loading of acetylcholine in synaptic vesicle
Acetylcholine synaptic vesicle docking and priming
Release of acetylcholine at the synapse
Synthesis of GABA by GAD1
Synthesis of GABA by GAD2
Loading of GABA into clathrin sculpted GABA transport vesicle lumen
GABA loaded synaptic vesicle Docking and Priming
Release of GABA at the synapse
Conversion of GABA to Succinate Semialdehyde
Conversion of succinate semialdehyde to succinate
Neurotransmitter Release Cycle
Norepinephrine Neurotransmitter Release Cycle
Serotonin Neurotransmitter Release Cycle
Glutamate Neurotransmitter Release Cycle
Dopamine Neurotransmitter Release Cycle
Acetylcholine Neurotransmitter Release Cycle
GABA synthesis, release, reuptake and degradation
GABA synthesis
Reuptake of GABA
Degradation of GABA