FADS1
FADSD5
UniProt:O60427 FADS1
FADS2
UniProt:O95864 FADS2
ABCD1
ALD
UniProt:P33897 ABCD1
ELOVL2
SSC2
UniProt:Q9NXB9 ELOVL2
ELOVL5
PRO0530
UniProt:Q9NYP7 ELOVL5
Activation of linoleic acid to linoleoyl-CoA
Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA
Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA
Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA
Elongation of arachidonyl-CoA to docosatetraenoyl-CoA
arachidonoyl-CoA + malonyl-CoA => 3-oxo-(7,10,13,16)-docosatetraenoyl-CoA + CO2 + CoASH [ELOVL5]
Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA
Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA
Translocation of tetracosapentaenoyl-CoA to peroxisomes
Peroxisomal beta-oxidation of tetracosapentaenoyl-CoA to Docosapentaenoyl-CoA
Translocation of DPA to the ER
Linoleic acid (LA) metabolism