EIF5A + spermidine <=> EIF5A(Dhp) + 1,3-diaminopropane
EIF5A(Dhp) + 1,3-diaminopropane <=> EIF5A + spermidine
EIF5A(Dhp) + O2 => EIF5A(Hyp)
Hypusine synthesis from eIF5A-lysine
Hypusinylation