PCK1
label: PEPCK1
label: UniProt:P35558 PCK1

AGL
label: GDE
label: UniProt:P35573 AGL

SLC20A3
label: SLC25A1
label: UniProt:P53007 SLC25A1

GBE1
label: UniProt:Q04446 GBE1

PCK2
label: PEPCK2
label: UniProt:Q16822 PCK2

DIC
label: SLC25A10
label: UniProt:Q9UBX3 SLC25A10

malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix]
type: Restriction
  on property: enabled by
  some values from: DIC
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005743
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005743
type: Restriction
  on property: enabled by
  some values from: DIC
type: GO_0005310
BFO_0000050: Gluconeogenesis
directly activates: (S)-malate + NAD+ <=> oxaloacetate + NADH + H+
directly activates: Catalysis1967

Glucose 6-phosphate is isomerized to form fructose-6-phosphate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004347
BFO_0000050: Glycolysis
directly activates: D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP
directly activates: D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP
directly activates: BiochemicalReaction4602
directly activates: BiochemicalReaction4604
directly activates: Catalysis1956
directly activates: Catalysis1957
directly activates: Catalysis2015
directly activates: Catalysis2017
directly activates: Control357
directly activates: Control358
directly activates: Control359
directly activates: Control360
directly activates: Control361
directly activates: Control362
label: alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate

Dephosphorylation of phosphoPFKFB1 by PP2A complex
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0008195
BFO_0000050: Glycolysis
directly activates: D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP
directly activates: Catalysis1956
directly activates: Control357

D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0003873
BFO_0000050: Glycolysis
label: Fructose 6-phosphate and ATP react to form fructose 2,6-bisphosphate and ADP

D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0003872
BFO_0000050: Glycolysis
directly activates: D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate
directly activates: Catalysis1958

D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004332
BFO_0000050: Glycolysis
directly activates: dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate
directly activates: Catalysis1959

dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004807
BFO_0000050: Glycolysis
directly activates: D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+
directly activates: BiochemicalReaction4600
directly activates: BiochemicalReaction4604
directly activates: Catalysis1960
directly activates: Catalysis2013
directly activates: Catalysis2017

D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004365
BFO_0000050: Glycolysis
directly activates: 1,3-Bisphosphoglycerate and ADP react to form 3-phosphoglycerate and ATP
directly activates: D-Glucose 1-phosphate <=> alpha-D-Glucose 6-phosphate
directly activates: Catalysis1961
directly activates: Catalysis2000
label: Glyceraldehyde 3 phosphate, NAD+, and orthophosphate react to form 1,3 bisphosphoglycerate and NADH + H+

1,3-Bisphosphoglycerate and ADP react to form 3-phosphoglycerate and ATP
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004618
BFO_0000050: Glycolysis
directly activates: 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate
directly activates: Catalysis1962
label: 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ADP

3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004619
BFO_0000050: Glycolysis
directly activates: 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O
directly activates: Catalysis1963

2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004634
BFO_0000050: Glycolysis
directly activates: phosphoenolpyruvate + ADP => pyruvate + ATP
directly activates: Catalysis1964
directly activates: Control363
directly activates: Control364
directly activates: Control365
directly activates: Control366

phosphoenolpyruvate + ADP => pyruvate + ATP
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004743
BFO_0000050: Glycolysis
directly activates: BiochemicalReaction5399
directly activates: BiochemicalReaction5403
directly activates: Catalysis2595
directly activates: Catalysis2599

Pyruvate + CO2 + ATP => ADP + Orthophosphate + Oxaloacetate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005759
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005759
type: GO_0004736
BFO_0000050: Gluconeogenesis
directly activates: Oxaloacetate + NADH + H+ <=> (S)-Malate + NAD+
directly activates: oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2]
directly activates: oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [mitochondrial matrix]
directly activates: Catalysis1966
directly activates: Catalysis1968
directly activates: Catalysis1973
label: Pyruvate, CO2, and ATP react to form oxaloacetate, ADP, and orthophosphate

Oxaloacetate + NADH + H+ <=> (S)-Malate + NAD+
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005759
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005759
type: GO_0030060
BFO_0000050: Gluconeogenesis
directly activates: malate [mitochondrial matrix] + orthophosphate [cytosol] <=> malate [cytosol] + orthophosphate [mitochondrial matrix]
directly activates: Exchange of malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane
directly activates: Catalysis1969
directly activates: Catalysis636

(S)-malate + NAD+ <=> oxaloacetate + NADH + H+
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0030060
BFO_0000050: Gluconeogenesis
directly activates: Oxaloacetate and GTP react to form phosphoenolpyruvate, CO2, and GDP [cytosol]
directly activates: Catalysis1972
label: malate + NAD+ <=> oxaloacetate + NADH + H+

oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2]
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005759
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005759
type: GO_0004069
BFO_0000050: Gluconeogenesis
directly activates: Exchange of cytosolic glutamate and mitochondrial aspartate
directly activates: BiochemicalReaction5706
directly activates: Catalysis1970
directly activates: Catalysis2866

Exchange of malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005743
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005743
type: GO_0015367
BFO_0000050: Gluconeogenesis
directly activates: (S)-malate + NAD+ <=> oxaloacetate + NADH + H+
directly activates: Catalysis1967
label: malate [mitochondrial matrix] + alpha-ketoglutarate [cytosol] <=> malate [cytosol] + alpha-ketoglutarate [mitochondrial matrix]

Exchange of cytosolic glutamate and mitochondrial aspartate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005743
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005743
type: GO_0015172
BFO_0000050: Gluconeogenesis
directly activates: aspartate + alpha-ketoglutarate <=> oxaloacetate + glutamate [GOT1]
directly activates: Catalysis1971
label: aspartate [mitochondrial matrix] + glutamate [cytosol] => aspartate [cytosol] + glutamate [mitochondrial matrix]

aspartate + alpha-ketoglutarate <=> oxaloacetate + glutamate [GOT1]
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004069
BFO_0000050: Gluconeogenesis
directly activates: Oxaloacetate and GTP react to form phosphoenolpyruvate, CO2, and GDP [cytosol]
directly activates: Catalysis1972

Oxaloacetate and GTP react to form phosphoenolpyruvate, CO2, and GDP [cytosol]
type: Restriction
  on property: enabled by
  some values from: PCK1
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: enabled by
  some values from: PCK1
type: GO_0004613
BFO_0000050: Gluconeogenesis
directly activates: Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate
directly activates: Catalysis1975
label: oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [cytosol]

oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [mitochondrial matrix]
type: Restriction
  on property: enabled by
  some values from: PCK2
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005759
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005759
type: Restriction
  on property: enabled by
  some values from: PCK2
type: GO_0004613
BFO_0000050: Gluconeogenesis
directly activates: Exchange of cytosolic citrate for mitochondrial phosphoenolpyruvate
directly activates: Catalysis1974

Exchange of cytosolic citrate for mitochondrial phosphoenolpyruvate
type: Restriction
  on property: enabled by
  some values from: SLC20A3
type: Restriction
  on property: enabled by
  some values from: SLC20A3
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005743
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005743
type: GO_0015142
BFO_0000050: Gluconeogenesis
directly activates: Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate
directly activates: Catalysis1975
label: phosphoenolpyruvate [mitochondrial matrix] + citrate [cytosol] => phosphoenolpyruvate [cytosol] + citrate [mitochondrial matrix]

Phosphoenolpyruvate + H2O <=> 2-Phospho-D-glycerate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004634
BFO_0000050: Gluconeogenesis
directly activates: 2-Phospho-D-glycerate <=> 3-Phospho-D-glycerate
directly activates: Catalysis1976

2-Phospho-D-glycerate <=> 3-Phospho-D-glycerate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004619
BFO_0000050: Gluconeogenesis
directly activates: ATP + 3-Phospho-D-glycerate <=> ADP + 1,3-bisphospho-D-glycerate
directly activates: Catalysis1977

ATP + 3-Phospho-D-glycerate <=> ADP + 1,3-bisphospho-D-glycerate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004618
BFO_0000050: Gluconeogenesis
directly activates: 1,3-bisphospho-D-glycerate + NADH + H+ <=> D-glyceraldehyde 3-phosphate + Orthophosphate + NAD+
directly activates: Catalysis1978

1,3-bisphospho-D-glycerate + NADH + H+ <=> D-glyceraldehyde 3-phosphate + Orthophosphate + NAD+
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004365
BFO_0000050: Gluconeogenesis
directly activates: D-glyceraldehyde 3-phosphate <=> dihydroxyacetone phosphate
directly activates: dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate <=> D-fructose 1,6-bisphosphate
directly activates: Catalysis1979
directly activates: Catalysis1980

D-glyceraldehyde 3-phosphate <=> dihydroxyacetone phosphate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004807
BFO_0000050: Gluconeogenesis
directly activates: dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate <=> D-fructose 1,6-bisphosphate
directly activates: Catalysis1980

dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate <=> D-fructose 1,6-bisphosphate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004332
BFO_0000050: Gluconeogenesis
directly activates: D-fructose 1,6-bisphosphate + H2O => D-fructose 6-phosphate + orthophosphate
directly activates: Catalysis1981
directly activates: Control368

D-fructose 1,6-bisphosphate + H2O => D-fructose 6-phosphate + orthophosphate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0042132
BFO_0000050: Gluconeogenesis
directly activates: D-fructose 6-phosphate <=> alpha-D-Glucose 6-phosphate
directly activates: Catalysis1984

Phosphorylation of PF2K-Pase by PKA catalytic subunit
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004691
BFO_0000050: Gluconeogenesis
directly activates: D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP
directly activates: Catalysis1956
directly activates: Control357

Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004331
BFO_0000050: Gluconeogenesis

D-fructose 6-phosphate <=> alpha-D-Glucose 6-phosphate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004347
BFO_0000050: Gluconeogenesis
directly activates: BiochemicalReaction1665
directly activates: BiochemicalReaction4594
directly activates: Catalysis2007
directly activates: Catalysis647

alpha-D-Glucose 6-phosphate <=> D-Glucose 1-phosphate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004614
BFO_0000050: Glycogen synthesis
directly activates: UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose
directly activates: Catalysis1986

UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0003983
BFO_0000050: Glycogen synthesis
directly activates: BiochemicalReaction296
directly activates: 8 UDP-glucose + glycogenin dimer => 8 UDP + {(1,4)-alpha-D-glucosyl}4 glycogenin dimer
directly activates: BiochemicalReaction5891
directly activates: Catalysis111
directly activates: Catalysis1987
directly activates: Catalysis3031
directly activates: Control14

8 UDP-glucose + glycogenin dimer => 8 UDP + {(1,4)-alpha-D-glucosyl}4 glycogenin dimer
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0008466
BFO_0000050: Glycogen synthesis
directly activates: 8 UDP-glucose + ((1,4)-alpha-D-glucosyl}4 glycogenin => 8 UDP + ((1,4)-alpha-D-glucosyl)8 glycogenin [GYS I form]
directly activates: 8 UDP-glucose + ((1,4)-alpha-D-glucosyl)4 glycogenin => 8 UDP + ((1,4)-alpha-D-glucosyl)8 glycogenin [GYS D form]
directly activates: Catalysis1988
directly activates: Catalysis1989
directly activates: Control370
directly activates: Modulation13

8 UDP-glucose + ((1,4)-alpha-D-glucosyl}4 glycogenin => 8 UDP + ((1,4)-alpha-D-glucosyl)8 glycogenin [GYS I form]
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004373
BFO_0000050: Glycogen synthesis
directly activates: poly((1,4)-alpha-D-glucosyl) glycogenin => glycogen-glycogenin
directly activates: Catalysis1990

8 UDP-glucose + ((1,4)-alpha-D-glucosyl)4 glycogenin => 8 UDP + ((1,4)-alpha-D-glucosyl)8 glycogenin [GYS D form]
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004373
BFO_0000050: Glycogen synthesis
directly activates: poly((1,4)-alpha-D-glucosyl) glycogenin => glycogen-glycogenin
directly activates: Catalysis1990

poly((1,4)-alpha-D-glucosyl) glycogenin => glycogen-glycogenin
type: Restriction
  on property: enabled by
  some values from: GBE1
type: Restriction
  on property: enabled by
  some values from: GBE1
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0003844
BFO_0000050: Glycogen synthesis

glycogen phosphorylase (PYGB) dimer b + 2 ATP => glycogen phosphorylase (PYGB) dimer a + 2 ADP
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004689
BFO_0000050: Glycogen breakdown (glycogenolysis)
directly activates: glycogen-glycogenin-1 + n orthophosphate => limit dextrin-glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB]
directly activates: poly((1,4)-alpha-glycosyl) glycogenin-1 + n orthophosphate => glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB]
directly activates: Catalysis1994
directly activates: Catalysis1998

glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004689
BFO_0000050: Glycogen breakdown (glycogenolysis)
directly activates: glycogen-glycogenin-1 + n orthophosphate => limit dextrin-glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB]
directly activates: poly((1,4)-alpha-glycosyl) glycogenin-1 + n orthophosphate => glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB]
directly activates: Catalysis1994
directly activates: Catalysis1998

glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004689
BFO_0000050: Glycogen breakdown (glycogenolysis)
directly activates: glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL]
directly activates: poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL]
directly activates: Catalysis1995
directly activates: Catalysis1999

PGYB dimer, b form + 2 AMP <=> PGYB b dimer:AMP complex
type: GO_0003674
BFO_0000050: Glycogen breakdown (glycogenolysis)
directly activates: glycogen-glycogenin-1 + n orthophosphate => limit dextrin-glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB]
directly activates: poly((1,4)-alpha-glycosyl) glycogenin-1 + n orthophosphate => glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB]
directly activates: Catalysis1994
directly activates: Catalysis1998

PGYB b dimer:AMP complex <=> PGYB dimer, b form + 2 AMP
type: GO_0003674
BFO_0000050: Glycogen breakdown (glycogenolysis)

PGYM dimer, b form + 2 AMP <=> PGYM b dimer:AMP complex
type: GO_0003674
BFO_0000050: Glycogen breakdown (glycogenolysis)
directly activates: glycogen-glycogenin-1 + n orthophosphate => limit dextrin-glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB]
directly activates: poly((1,4)-alpha-glycosyl) glycogenin-1 + n orthophosphate => glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB]
directly activates: Catalysis1994
directly activates: Catalysis1998

PGYM b dimer:AMP complex <=> PGYM dimer, b form + 2 AMP
type: GO_0003674
BFO_0000050: Glycogen breakdown (glycogenolysis)

glycogen-glycogenin-1 + n orthophosphate => limit dextrin-glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB]
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0008184
BFO_0000050: Glycogen breakdown (glycogenolysis)
directly activates: limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin
directly activates: D-Glucose 1-phosphate <=> alpha-D-Glucose 6-phosphate
directly activates: Catalysis1996
directly activates: Catalysis2000

glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL]
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0008184
BFO_0000050: Glycogen breakdown (glycogenolysis)
directly activates: UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose
directly activates: limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin
directly activates: D-Glucose 1-phosphate <=> alpha-D-Glucose 6-phosphate
directly activates: Catalysis1986
directly activates: Catalysis1996
directly activates: Catalysis2000

limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin
type: Restriction
  on property: enabled by
  some values from: AGL
type: Restriction
  on property: enabled by
  some values from: AGL
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004134
BFO_0000050: Glycogen breakdown (glycogenolysis)
directly activates: ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose
directly activates: Catalysis1997

((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose
type: Restriction
  on property: enabled by
  some values from: AGL
type: Restriction
  on property: enabled by
  some values from: AGL
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004135
BFO_0000050: Glycogen breakdown (glycogenolysis)
directly activates: poly((1,4)-alpha-glycosyl) glycogenin-1 + n orthophosphate => glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB]
directly activates: poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL]
directly activates: Catalysis1998
directly activates: Catalysis1999

poly((1,4)-alpha-glycosyl) glycogenin-1 + n orthophosphate => glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB]
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0008184
BFO_0000050: Glycogen breakdown (glycogenolysis)
directly activates: D-Glucose 1-phosphate <=> alpha-D-Glucose 6-phosphate
directly activates: Catalysis2000

poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL]
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0008184
BFO_0000050: Glycogen breakdown (glycogenolysis)
directly activates: D-Glucose 1-phosphate <=> alpha-D-Glucose 6-phosphate
directly activates: Catalysis2000

D-Glucose 1-phosphate <=> alpha-D-Glucose 6-phosphate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004614
BFO_0000050: Glycogen breakdown (glycogenolysis)
directly activates: BiochemicalReaction4594
directly activates: Catalysis2007

Glucose metabolism
type: GO_0008150

Glycolysis
type: GO_0008150
BFO_0000050: Glucose metabolism

Gluconeogenesis
type: GO_0008150
BFO_0000050: Glucose metabolism

Glycogen synthesis
type: GO_0008150
BFO_0000050: Glucose metabolism

Glycogen breakdown (glycogenolysis)
type: GO_0008150
BFO_0000050: Glucose metabolism