DYRK
DYRK1A
MNB
MNBH
UniProt:Q13627 DYRK1A
Phosphorylation of LIN52 component of MuvB by DYRK1A
p130 (RBL2) associates with MuvB to form DREAM complex
Transcription of E2F targets under negative control by DREAM complex
HDAC1 + p107(RBL1):E2F4:DP1 => HDAC1-p107(RBL2):E2F4:DP1
Recruitment of HDAC1 by p107 (RBL1)
HDAC1 + p130(RBL2):E2F4/5:DP1 => HDAC1-p130(RBL2):E2F4/5:DP1
Recruitment of HDAC1 by p130 (RBL2)
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
p107 (RBL1) binds CyclinE/A:CDK2
p107 (RBL1) in complex with E2F4:DP1/2 binds to cyclin E/A:CDK2
p130 (RBL2) binds Cyclin E/A:CDK2
p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2
G0 and Early G1