ERBB4 binds WWP1/ITCH ubiquitin ligases
type: GO_0003674
BFO_0000050: Downregulation of ERBB4 signaling
directly activates: ERBB4 ubiquitination by WWP1/ITCH
directly activates: Catalysis1846

ERBB4 ubiquitination by WWP1/ITCH
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0004842
BFO_0000050: Downregulation of ERBB4 signaling

NEDD4 binds ERBB4jmAcyt1s80 dimer
type: GO_0003674
BFO_0000050: Downregulation of ERBB4 signaling

NEDD4 ubiquitinates ERBB4jmAcyt1s80 dimer
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004842
BFO_0000050: Downregulation of ERBB4 signaling

Downregulation of ERBB4 signaling
type: GO_0008150