CHST14
label: D4ST1
label: UNQ1925/PRO4400
label: UniProt:Q8NCH0 CHST14

DSE
label: SART2
label: UniProt:Q9UL01 DSE

DS2ST
label: UST
label: UniProt:Q9Y2C2 UST

Dermatan-sulfate epimerase (DSE) converts chondroitin sulfate (CS) to dermatan sulfate (DS)
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: enabled by
  some values from: DSE
type: GO_0047757
BFO_0000050: Dermatan sulfate biosynthesis
directly activates: Dermatan sulfate can be further sulfated on position 2 of iduronate
directly activates: DSPGs are secreted
directly activates: Catalysis1350

Dermatan sulfate can be further sulfated on position 2 of iduronate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: enabled by
  some values from: DS2ST
type: GO_0008146
BFO_0000050: Dermatan sulfate biosynthesis
directly activates: CHST14 transfers SO4(2-) to DS
directly activates: DSPGs are secreted
directly activates: Catalysis1351

CHST14 transfers SO4(2-) to DS
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: enabled by
  some values from: CHST14
type: GO_0001537
BFO_0000050: Dermatan sulfate biosynthesis
directly activates: DSPGs are secreted
label: GalNAc is sulfated on position 4 once dermatan sulfate is formed

DSPGs are secreted
type: GO_0003674
BFO_0000050: Dermatan sulfate biosynthesis
directly activates: BiochemicalReaction3124

Dermatan sulfate biosynthesis
type: GO_0008150