BPNT1
label: UniProt:O95861 BPNT1

SLC26A1,2 transport extracellular SO4(2-) to cytosol
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0015116
BFO_0000050: Transport and synthesis of PAPS
directly activates: ATP + sulfate => adenylyl sulfate (APS) + pyrophosphate
directly activates: Catalysis1300

SLC35B2,3 transport cytosolic PAPS to Golgi lumen
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: Restriction
  on property: BFO_0000066
  some values from: GO_0000139
type: GO_0046964
BFO_0000050: Transport and synthesis of PAPS
directly activates: BiochemicalReaction3073
directly activates: BiochemicalReaction3074
directly activates: BiochemicalReaction3091
directly activates: BiochemicalReaction3093
directly activates: BiochemicalReaction3094
directly activates: BiochemicalReaction3095
directly activates: BiochemicalReaction3097
directly activates: BiochemicalReaction3116
directly activates: BiochemicalReaction3117
directly activates: BiochemicalReaction3118
directly activates: BiochemicalReaction3121
directly activates: BiochemicalReaction3122
directly activates: Catalysis1307
directly activates: Catalysis1308
directly activates: Catalysis1323
directly activates: Catalysis1325
directly activates: Catalysis1326
directly activates: Catalysis1327
directly activates: Catalysis1329
directly activates: Catalysis1346
directly activates: Catalysis1347
directly activates: Catalysis1348
directly activates: Catalysis1350
directly activates: Catalysis1351

ATP + sulfate => adenylyl sulfate (APS) + pyrophosphate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004781
BFO_0000050: Transport and synthesis of PAPS
directly activates: BiochemicalReaction296
directly activates: APS reacts with another ATP molecule to form PAPS
directly activates: Catalysis111
directly activates: Catalysis1301
directly activates: Control14
label: Activation of inorganic sulfate forms APS
label: PAPSS1,2 transfer PO4(2-) group from ATP to form APS

APS reacts with another ATP molecule to form PAPS
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004020
BFO_0000050: Transport and synthesis of PAPS
directly activates: SLC35B2,3 transport cytosolic PAPS to Golgi lumen
directly activates: Acetaminophen can form an O- sulfate conjugate
directly activates: N-hydroxy-4-aminobiphenyl can form a sulfate conjugate
directly activates: Phenol can form a sulfate conjugate
directly activates: Dopamine can form an O-sulfate conjugate
directly activates: 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP
directly activates: 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP
directly activates: p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP
directly activates: N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP
directly activates: cholesterol + PAPS => cholesterol sulfate + PAP
directly activates: 27-hydroxycholesterol + PAPS => 27-hydroxycholesterol 3-sulfate + PAP
directly activates: SULTs transfer (SO4)2- group to PREG
directly activates: estrone + PAPS => estrone 3-sulfate + PAP
directly activates: dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP
directly activates: beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP
directly activates: lithocholate + PAPS => lithocholate sulfate + PAP
directly activates: taurolithocholate + PAPS => taurolithocholate sulfate + PAP
directly activates: Catalysis3034
directly activates: Catalysis3035
directly activates: Catalysis3036
directly activates: Catalysis3037
directly activates: Catalysis3038
directly activates: Catalysis3039
directly activates: Catalysis3040
directly activates: Catalysis3041
directly activates: Catalysis3042
directly activates: Catalysis3043
directly activates: Catalysis3044
directly activates: Catalysis3045
directly activates: Catalysis3046
directly activates: Catalysis3047
directly activates: Catalysis3048
directly activates: Catalysis3049
directly activates: Catalysis723
label: PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS
label: adenylyl sulfate (APS) + ATP => PAPS + ADP

Acetaminophen can form an O- sulfate conjugate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004062
BFO_0000050: Cytosolic sulfonation of small molecules
directly activates: Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate
directly activates: Catalysis3050

N-hydroxy-4-aminobiphenyl can form a sulfate conjugate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004062
BFO_0000050: Cytosolic sulfonation of small molecules
directly activates: Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate
directly activates: Catalysis3050

Phenol can form a sulfate conjugate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004062
BFO_0000050: Cytosolic sulfonation of small molecules
directly activates: Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate
directly activates: Catalysis3050

Dopamine can form an O-sulfate conjugate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004062
BFO_0000050: Cytosolic sulfonation of small molecules
directly activates: Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate
directly activates: Catalysis3050

3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004062
BFO_0000050: Cytosolic sulfonation of small molecules
directly activates: Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate
directly activates: Catalysis3050

3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004062
BFO_0000050: Cytosolic sulfonation of small molecules
directly activates: Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate
directly activates: Catalysis3050

p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004062
BFO_0000050: Cytosolic sulfonation of small molecules
directly activates: Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate
directly activates: Catalysis3050

N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0008146
BFO_0000050: Cytosolic sulfonation of small molecules
directly activates: Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate
directly activates: Catalysis3050

cholesterol + PAPS => cholesterol sulfate + PAP
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004027
BFO_0000050: Cytosolic sulfonation of small molecules
directly activates: Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate
directly activates: Catalysis3050

27-hydroxycholesterol + PAPS => 27-hydroxycholesterol 3-sulfate + PAP
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004027
BFO_0000050: Cytosolic sulfonation of small molecules
directly activates: Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate
directly activates: Catalysis3050
label: SULTs transfer (SO4)2- group to 27HCHOL

SULTs transfer (SO4)2- group to PREG
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0050294
BFO_0000050: Cytosolic sulfonation of small molecules
directly activates: Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate
directly activates: Catalysis3050
label: pregnenolone + PAPS => pregnenolone sulfate + PAP

estrone + PAPS => estrone 3-sulfate + PAP
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004304
BFO_0000050: Cytosolic sulfonation of small molecules
directly activates: Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate
directly activates: Catalysis3050

dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0050294
BFO_0000050: Cytosolic sulfonation of small molecules
directly activates: Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate
directly activates: Catalysis3050

beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0050294
BFO_0000050: Cytosolic sulfonation of small molecules
directly activates: Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate
directly activates: Catalysis3050

lithocholate + PAPS => lithocholate sulfate + PAP
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0008146
BFO_0000050: Cytosolic sulfonation of small molecules
directly activates: Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate
directly activates: Catalysis3050

taurolithocholate + PAPS => taurolithocholate sulfate + PAP
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0008146
BFO_0000050: Cytosolic sulfonation of small molecules
directly activates: Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate
directly activates: Catalysis3050

Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: enabled by
  some values from: BPNT1
type: GO_0008441
type: GO_0050427
BFO_0000050: Cytosolic sulfonation of small molecules

Cytosolic sulfonation of small molecules
type: GO_0008150

Transport and synthesis of PAPS
type: GO_0008150
BFO_0000050: Cytosolic sulfonation of small molecules