BTD
UniProt:P43251 BTD
HLCS
UniProt:P50747 HLCS
SLC5A6
SMVT
UniProt:Q9Y289 SLC5A6
SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol
biotin [extracellular] + 2 Na+ [extracellular] => biotin [cytosol] + 2 Na+ [cytosol]
HLCS biotinylates PCCA:PCCB
HLCS biotinylates PC:Mn2+
HLCS biotinylates MCCC1:MCCC2
Cytoslic carboxylases translocate to mitochondrial matrix
HLCS biotinylates ACACA/B:Mn2+
An unknown protease degrades hCBXs
An unknown protease degrades ACACA/B:Mn2+
BCTN translocates to extracellular region
BTD hydrolyses BCTN
Biotin transport and metabolism