ACAS2
label: ACSS2
label: UniProt:Q9NR19 ACSS2

ACAS2L
label: ACSS1
label: KIAA1846
label: UniProt:Q9NUB1 ACSS1

Ethanol is oxidized by NAD+ to form acetaldehyde, NADH, and H+
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004024
BFO_0000050: Alcohol catabolism
directly activates: acetaldehyde [cytosolic] => acetaldehyde [mitochondrial]
directly activates: acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic]
directly activates: Catalysis3029
label: ethanol + NAD+ => acetaldehyde + NADH + H+

acetaldehyde [cytosolic] => acetaldehyde [mitochondrial]
type: GO_0003674
BFO_0000050: Alcohol catabolism
directly activates: acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial]
directly activates: Catalysis3027

acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial]
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005759
type: GO_0004029
BFO_0000050: Alcohol catabolism
directly activates: acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial]
directly activates: Catalysis3028

acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial]
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005759
type: Restriction
  on property: enabled by
  some values from: ACAS2L
type: GO_0003987
BFO_0000050: Alcohol catabolism

acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic]
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004029
BFO_0000050: Alcohol catabolism
directly activates: acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic]
directly activates: Catalysis3030

acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic]
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: enabled by
  some values from: ACAS2
type: GO_0003987
BFO_0000050: Alcohol catabolism
directly activates: BiochemicalReaction296
directly activates: Catalysis111
directly activates: Control14

Alcohol catabolism
type: GO_0008150
label: Ethanol oxidation