ABCB1
label: MDR1
label: PGY1
label: UniProt:P08183 ABCB1

OCT (organic cation transporter)-mediated abacavir uptake
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0015101
BFO_0000050: Abacavir transmembrane transport
directly activates: ABCG2-mediated abacavir efflux
directly activates: ABCB1-mediated abacavir efflux
directly activates: BiochemicalReaction5955
directly activates: BiochemicalReaction5956
directly activates: Catalysis3085
directly activates: Catalysis3086
directly activates: Catalysis3087
directly activates: Catalysis3088
label: abacavir [extracellular] => abacavir [cytosol]

ABCG2-mediated abacavir efflux
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: GO_0008559
BFO_0000050: Abacavir transmembrane transport
label: abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate

ABCB1-mediated abacavir efflux
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005886
type: Restriction
  on property: enabled by
  some values from: ABCB1
type: GO_0008559
BFO_0000050: Abacavir transmembrane transport
label: abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate

Abacavir transmembrane transport
type: GO_0008150