*reference: PMID:21283692
*table: tableS2
*description: Top 30 up and top 30 down regulated genes in AD frontal lobe.
*original_results: Interestingly, the frontal lobe is different from the other samples in that it shows greater changes in genes associated with brain-specific biological processes. These are regulation of synaptic transmission (rank 9), neurotransmitter transport (11), response to metal ion (13), metal ion transport (15), regulation of synaptic plasticity (18), negative regulation of neuron apoptosis (19) and axon transport (20)...Genes known to be involved in programmed cell death were enriched in the frontal lobe of AD brain (rank 10) and an induction of apoptosis is present in both frontal and temporal lobes (rank 16 and 12, respectively). An over-representation of apoptosis-related genes clearly indicates the ongoing process of neurodegeneration and associated cell loss
*original_tool: DAVID
*reference_set: 9606
*expected_enriched_term: 
*item_id_type: symbol
###
PCK1
CD163
AC012317.1
NUPR1
GDPD3
STAB1
MOV10
MLKL
LY6G5C
ITPR3
TEAD4
ZDHHC11B
LY96
RP4-697K14.12
GRK4
SLC26A1
DHX58
MT1X
C1QB
FGF17
ZCCHC11
MKNK2
DIP2C
CLDN15
NBPF1
MKNK2
C1R
RARRES3
DNASE1L2
SCRIB
STAT1
DHTKD1
ENTPD3
STXBP5
KIAA0319
GRM5
SLC4A4
PLD4
SLCO1C1
WDR17
ATP6V1A
ANKRD52
HTT
ANKFY1
MAN1A1
ATP10B
RIMS1
SUSD1
ATP8A2
DHTKD1
TFRC
GAPVD1
VWF
ATP8A1
EDEM3
ACOX1
GPR107
NAG
ATRN
LPIN2
PTPRO
SLIT1