-------------------------------------------------------------------------------- UniProt - Swiss-Prot Protein Knowledgebase SIB Swiss Institute of Bioinformatics; Geneva, Switzerland European Bioinformatics Institute (EBI); Hinxton, United Kingdom Protein Information Resource (PIR); Washington DC, USA -------------------------------------------------------------------------------- Description: Human and mouse protein kinases: classification and index Name: pkinfam.txt Release: 2022_03 of 03-Aug-2022 -------------------------------------------------------------------------------- Introduction ------------ Phosphorylation by protein kinases is a universal cell-signaling fundamental process in eukaryotic cells [1]. The comprehensive cataloging of the protein kinase complement of the human genome has been done by the groups of Manning [2] and Miranda-Saavedra [3]. The list of all UniProtKB/Swiss-Prot human and mouse protein kinases, systematically classified is aimed at facilitating the retrieval of all kinases of the human and mouse kinomes. The protein kinases are subdivided in the following families or subgroups: * AGC; containing the PKA, PKG and PKC subfamilies * CAMK; calcium/calmodulin-dependent protein kinases * CK1; casein kinase 1 * CMGC; containing the CDK, MAPK, GSK3 and CLK sufamilies * NEK; * RGC; receptor guanylate cyclases * STE; * TKL; tyrosine protein kinase-like * Tyr; tyrosine protein kinase * Other; Atypical * ADCK; * Alpha-type; * FAST; * PDK/BCKDK; * PI3/PI4-kinase; * RIO-type. References ---------- [ 1] PubMed=10647936; Hunter T. Signaling -- 2000 and beyond. Cell 100:113-127(2000). [ 2] PubMed=12471243; DOI=10.1126/science.1075762; Manning G., Whyte D.B., Martinez R., Hunter T., Sudarsanam S. The protein kinase complement of the human genome. Science 298:1912-1934(2002). [ 3] PubMed=17557329; DOI=10.1002/prot.21444; Miranda-Saavedra D., Barton G.J. "Classification and functional annotation of eukaryotic protein kinases. Proteins 68:893-914(2007). Additional information on the classification of protein kinases is available at: http://kinase.com/ --------------------------------------------------------------- ====================================== Swiss-Prot entries for protein kinases ====================================== ================================= AGC Ser/Thr protein kinase family ================================= AKT1 AKT1_HUMAN (P31749 ) AKT1_MOUSE (P31750) AKT2 AKT2_HUMAN (P31751 ) AKT2_MOUSE (Q60823) AKT3 AKT3_HUMAN (Q9Y243 ) AKT3_MOUSE (Q9WUA6) CDC42BPA MRCKA_HUMAN (Q5VT25 ) MRCKA_MOUSE (Q3UU96) CDC42BPB MRCKB_HUMAN (Q9Y5S2 ) MRCKB_MOUSE (Q7TT50) CDC42BPG MRCKG_HUMAN (Q6DT37 ) MRCKG_MOUSE (Q80UW5) CIT CTRO_HUMAN (O14578 ) CTRO_MOUSE (P49025) DMPK DMPK_HUMAN (Q09013 ) DMPK_MOUSE (P54265) GRK1 GRK1_HUMAN (Q15835 ) GRK1_MOUSE (Q9WVL4) GRK2 ARBK1_HUMAN (P25098 ) ARBK1_MOUSE (Q99MK8) GRK3 ARBK2_HUMAN (P35626 ) ARBK2_MOUSE (Q3UYH7) GRK4 GRK4_HUMAN (P32298 ) GRK4_MOUSE (O70291) GRK5 GRK5_HUMAN (P34947 ) GRK5_MOUSE (Q8VEB1) GRK6 GRK6_HUMAN (P43250 ) GRK6_MOUSE (O70293) GRK7 GRK7_HUMAN (Q8WTQ7 ) LATS1 LATS1_HUMAN (O95835 ) LATS1_MOUSE (Q8BYR2) LATS2 LATS2_HUMAN (Q9NRM7 ) LATS2_MOUSE (Q7TSJ6) MAST1 MAST1_HUMAN (Q9Y2H9 ) MAST1_MOUSE (Q9R1L5) MAST2 MAST2_HUMAN (Q6P0Q8 ) MAST2_MOUSE (Q60592) MAST3 MAST3_HUMAN (O60307 ) MAST3_MOUSE (Q3U214) MAST4 MAST4_HUMAN (O15021 ) MAST4_MOUSE (Q811L6) MASTL GWL_HUMAN (Q96GX5 ) GWL_MOUSE (Q8C0P0) PDPK1 PDPK1_HUMAN (O15530 ) PDPK1_MOUSE (Q9Z2A0) PDPK2P PDPK2_HUMAN (Q6A1A2 ) PKN1 PKN1_HUMAN (Q16512 ) PKN1_MOUSE (P70268) PKN2 PKN2_HUMAN (Q16513 ) PKN2_MOUSE (Q8BWW9) PKN3 PKN3_HUMAN (Q6P5Z2 ) PKN3_MOUSE (Q8K045) PRKACA KAPCA_HUMAN (P17612 ) KAPCA_MOUSE (P05132) PRKACB KAPCB_HUMAN (P22694 ) KAPCB_MOUSE (P68181) PRKACG KAPCG_HUMAN (P22612 ) PRKCA KPCA_HUMAN (P17252 ) KPCA_MOUSE (P20444) PRKCB KPCB_HUMAN (P05771 ) KPCB_MOUSE (P68404) PRKCD KPCD_HUMAN (Q05655 ) KPCD_MOUSE (P28867) PRKCE KPCE_HUMAN (Q02156 ) KPCE_MOUSE (P16054) PRKCG KPCG_HUMAN (P05129 ) KPCG_MOUSE (P63318) PRKCH KPCL_HUMAN (P24723 ) KPCL_MOUSE (P23298) PRKCI KPCI_HUMAN (P41743 ) KPCI_MOUSE (Q62074) PRKCQ KPCT_HUMAN (Q04759 ) KPCT_MOUSE (Q02111) PRKCZ KPCZ_HUMAN (Q05513 ) KPCZ_MOUSE (Q02956) PRKG1 KGP1_HUMAN (Q13976 ) KGP1_MOUSE (P0C605) PRKG2 KGP2_HUMAN (Q13237 ) KGP2_MOUSE (Q61410) PRKX PRKX_HUMAN (P51817 ) PRKX_MOUSE (Q922R0) PRKY PRKY_HUMAN (O43930 ) ROCK1 ROCK1_HUMAN (Q13464 ) ROCK1_MOUSE (P70335) ROCK2 ROCK2_HUMAN (O75116 ) ROCK2_MOUSE (P70336) RPS6KA1 KS6A1_HUMAN (Q15418 ) KS6A1_MOUSE (P18653) RPS6KA2 KS6A2_HUMAN (Q15349 ) KS6A2_MOUSE (Q9WUT3) RPS6KA3 KS6A3_HUMAN (P51812 ) KS6A3_MOUSE (P18654) RPS6KA4 KS6A4_HUMAN (O75676 ) KS6A4_MOUSE (Q9Z2B9) RPS6KA5 KS6A5_HUMAN (O75582 ) KS6A5_MOUSE (Q8C050) RPS6KA6 KS6A6_HUMAN (Q9UK32 ) KS6A6_MOUSE (Q7TPS0) RPS6KB1 KS6B1_HUMAN (P23443 ) KS6B1_MOUSE (Q8BSK8) RPS6KB2 KS6B2_HUMAN (Q9UBS0 ) KS6B2_MOUSE (Q9Z1M4) SGK1 SGK1_HUMAN (O00141 ) SGK1_MOUSE (Q9WVC6) SGK2 SGK2_HUMAN (Q9HBY8 ) SGK2_MOUSE (Q9QZS5) SGK3 SGK3_HUMAN (Q96BR1 ) SGK3_MOUSE (Q9ERE3) STK38 STK38_HUMAN (Q15208 ) STK38_MOUSE (Q91VJ4) STK38L ST38L_HUMAN (Q9Y2H1 ) ST38L_MOUSE (Q7TSE6) ================================== CAMK Ser/Thr protein kinase family ================================== SMKX_MOUSE (Q8C0X8) BRSK1 BRSK1_HUMAN (Q8TDC3 ) BRSK1_MOUSE (Q5RJI5) BRSK2 BRSK2_HUMAN (Q8IWQ3 ) BRSK2_MOUSE (Q69Z98) CAMK1 KCC1A_HUMAN (Q14012 ) KCC1A_MOUSE (Q91YS8) CAMK1D KCC1D_HUMAN (Q8IU85 ) KCC1D_MOUSE (Q8BW96) CAMK1G KCC1G_HUMAN (Q96NX5 ) KCC1G_MOUSE (Q91VB2) CAMK2A KCC2A_HUMAN (Q9UQM7 ) KCC2A_MOUSE (P11798) CAMK2B KCC2B_HUMAN (Q13554 ) KCC2B_MOUSE (P28652) CAMK2D KCC2D_HUMAN (Q13557 ) KCC2D_MOUSE (Q6PHZ2) CAMK2G KCC2G_HUMAN (Q13555 ) KCC2G_MOUSE (Q923T9) CAMK4 KCC4_HUMAN (Q16566 ) KCC4_MOUSE (P08414) CAMKV CAMKV_HUMAN (Q8NCB2 ) CAMKV_MOUSE (Q3UHL1) CASK CSKP_HUMAN (O14936 ) CSKP_MOUSE (O70589) CHEK1 CHK1_HUMAN (O14757 ) CHK1_MOUSE (O35280) CHEK2 CHK2_HUMAN (O96017 ) CHK2_MOUSE (Q9Z265) DAPK1 DAPK1_HUMAN (P53355 ) DAPK1_MOUSE (Q80YE7) DAPK2 DAPK2_HUMAN (Q9UIK4 ) DAPK2_MOUSE (Q8VDF3) DAPK3 DAPK3_HUMAN (O43293 ) DAPK3_MOUSE (O54784) DCLK1 DCLK1_HUMAN (O15075 ) DCLK1_MOUSE (Q9JLM8) DCLK2 DCLK2_HUMAN (Q8N568 ) DCLK2_MOUSE (Q6PGN3) DCLK3 DCLK3_HUMAN (Q9C098 ) DCLK3_MOUSE (Q8BWQ5) Gm4922 SMKZ_MOUSE (Q8C0N0) Gm7168 SMKY_MOUSE (A0AUV4) HUNK HUNK_HUMAN (P57058 ) HUNK_MOUSE (O88866) KALRN KALRN_HUMAN (O60229 ) KALRN_MOUSE (A2CG49) MAPKAPK2 MAPK2_HUMAN (P49137 ) MAPK2_MOUSE (P49138) MAPKAPK3 MAPK3_HUMAN (Q16644 ) MAPK3_MOUSE (Q3UMW7) MAPKAPK5 MAPK5_HUMAN (Q8IW41 ) MAPK5_MOUSE (O54992) MARK1 MARK1_HUMAN (Q9P0L2 ) MARK1_MOUSE (Q8VHJ5) MARK2 MARK2_HUMAN (Q7KZI7 ) MARK2_MOUSE (Q05512) MARK3 MARK3_HUMAN (P27448 ) MARK3_MOUSE (Q03141) MARK4 MARK4_HUMAN (Q96L34 ) MARK4_MOUSE (Q8CIP4) MELK MELK_HUMAN (Q14680 ) MELK_MOUSE (Q61846) MKNK1 MKNK1_HUMAN (Q9BUB5 ) MKNK1_MOUSE (O08605) MKNK2 MKNK2_HUMAN (Q9HBH9 ) MKNK2_MOUSE (Q8CDB0) MYLK MYLK_HUMAN (Q15746 ) MYLK_MOUSE (Q6PDN3) MYLK2 MYLK2_HUMAN (Q9H1R3 ) MYLK2_MOUSE (Q8VCR8) MYLK3 MYLK3_HUMAN (Q32MK0 ) MYLK3_MOUSE (Q3UIZ8) MYLK4 MYLK4_HUMAN (Q86YV6 ) MYLK4_MOUSE (Q5SUV5) NIM1K NIM1_HUMAN (Q8IY84 ) NIM1_MOUSE (Q8BHI9) NUAK1 NUAK1_HUMAN (O60285 ) NUAK1_MOUSE (Q641K5) NUAK2 NUAK2_HUMAN (Q9H093 ) NUAK2_MOUSE (Q8BZN4) OBSCN OBSCN_HUMAN (Q5VST9 ) OBSCN_MOUSE (A2AAJ9) PASK PASK_HUMAN (Q96RG2 ) PASK_MOUSE (Q8CEE6) PHKG1 PHKG1_HUMAN (Q16816 ) PHKG1_MOUSE (P07934) PHKG2 PHKG2_HUMAN (P15735 ) PHKG2_MOUSE (Q9DB30) PIM1 PIM1_HUMAN (P11309 ) PIM1_MOUSE (P06803) PIM2 PIM2_HUMAN (Q9P1W9 ) PIM2_MOUSE (Q62070) PIM3 PIM3_HUMAN (Q86V86 ) PIM3_MOUSE (P58750) PNCK KCC1B_HUMAN (Q6P2M8 ) KCC1B_MOUSE (Q9QYK9) PRKAA1 AAPK1_HUMAN (Q13131 ) AAPK1_MOUSE (Q5EG47) PRKAA2 AAPK2_HUMAN (P54646 ) AAPK2_MOUSE (Q8BRK8) PRKD1 KPCD1_HUMAN (Q15139 ) KPCD1_MOUSE (Q62101) PRKD2 KPCD2_HUMAN (Q9BZL6 ) KPCD2_MOUSE (Q8BZ03) PRKD3 KPCD3_HUMAN (O94806 ) KPCD3_MOUSE (Q8K1Y2) PSKH1 KPSH1_HUMAN (P11801 ) KPSH1_MOUSE (Q91YA2) PSKH2 KPSH2_HUMAN (Q96QS6 ) SIK1 SIK1_HUMAN (P57059 ) SIK1_MOUSE (Q60670) SIK1B SIK1B_HUMAN (A0A0B4J2F2) SIK2 SIK2_HUMAN (Q9H0K1 ) SIK2_MOUSE (Q8CFH6) SIK3 SIK3_HUMAN (Q9Y2K2 ) SIK3_MOUSE (Q6P4S6) SNRK SNRK_HUMAN (Q9NRH2 ) SNRK_MOUSE (Q8VDU5) SPEG SPEG_HUMAN (Q15772 ) SPEG_MOUSE (Q62407) STK11 STK11_HUMAN (Q15831 ) STK11_MOUSE (Q9WTK7) STK17A ST17A_HUMAN (Q9UEE5 ) STK17B ST17B_HUMAN (O94768 ) ST17B_MOUSE (Q8BG48) STK33 STK33_HUMAN (Q9BYT3 ) STK33_MOUSE (Q924X7) STK40 STK40_HUMAN (Q8N2I9 ) STK40_MOUSE (Q7TNL3) Smok2a SMK2A_MOUSE (Q9QYZ6) Smok2b SMK2B_MOUSE (Q9QYZ3) Smok3a SMK3A_MOUSE (C0HKC8) Smok3b SMK3B_MOUSE (C0HKC9) Stk-ps2 SMKW_MOUSE (Q8C0V7) TRIB1 TRIB1_HUMAN (Q96RU8 ) TRIB1_MOUSE (Q8K4K4) TRIB2 TRIB2_HUMAN (Q92519 ) TRIB2_MOUSE (Q8K4K3) TRIB3 TRIB3_HUMAN (Q96RU7 ) TRIB3_MOUSE (Q8K4K2) TRIO TRIO_HUMAN (O75962 ) TRIO_MOUSE (Q0KL02) TSSK1B TSSK1_HUMAN (Q9BXA7 ) TSSK1_MOUSE (Q61241) TSSK2 TSSK2_HUMAN (Q96PF2 ) TSSK2_MOUSE (O54863) TSSK3 TSSK3_HUMAN (Q96PN8 ) TSSK3_MOUSE (Q9D2E1) TSSK4 TSSK4_HUMAN (Q6SA08 ) TSSK4_MOUSE (Q9D411) TSSK6 TSSK6_HUMAN (Q9BXA6 ) TSSK6_MOUSE (Q925K9) TTN TITIN_HUMAN (Q8WZ42 ) TITIN_MOUSE (A2ASS6) Tssk5 TSSK5_MOUSE (Q8C1R0) ================================= CK1 Ser/Thr protein kinase family ================================= CSNK1A1 KC1A_HUMAN (P48729 ) KC1A_MOUSE (Q8BK63) CSNK1A1L KC1AL_HUMAN (Q8N752 ) CSNK1D KC1D_HUMAN (P48730 ) KC1D_MOUSE (Q9DC28) CSNK1E KC1E_HUMAN (P49674 ) KC1E_MOUSE (Q9JMK2) CSNK1G1 KC1G1_HUMAN (Q9HCP0 ) KC1G1_MOUSE (Q8BTH8) CSNK1G2 KC1G2_HUMAN (P78368 ) KC1G2_MOUSE (Q8BVP5) CSNK1G3 KC1G3_HUMAN (Q9Y6M4 ) KC1G3_MOUSE (Q8C4X2) TTBK1 TTBK1_HUMAN (Q5TCY1 ) TTBK1_MOUSE (Q6PCN3) TTBK2 TTBK2_HUMAN (Q6IQ55 ) TTBK2_MOUSE (Q3UVR3) VRK1 VRK1_HUMAN (Q99986 ) VRK1_MOUSE (Q80X41) VRK2 VRK2_HUMAN (Q86Y07 ) VRK2_MOUSE (Q8BN21) VRK3 VRK3_HUMAN (Q8IV63 ) VRK3_MOUSE (Q8K3G5) ================================== CMGC Ser/Thr protein kinase family ================================== CDK1 CDK1_HUMAN (P06493 ) CDK1_MOUSE (P11440) CDK10 CDK10_HUMAN (Q15131 ) CDK10_MOUSE (Q3UMM4) CDK11A CD11A_HUMAN (Q9UQ88 ) CDK11B CD11B_HUMAN (P21127 ) CD11B_MOUSE (P24788) CDK12 CDK12_HUMAN (Q9NYV4 ) CDK12_MOUSE (Q14AX6) CDK13 CDK13_HUMAN (Q14004 ) CDK13_MOUSE (Q69ZA1) CDK14 CDK14_HUMAN (O94921 ) CDK14_MOUSE (O35495) CDK15 CDK15_HUMAN (Q96Q40 ) CDK15_MOUSE (Q3V3A1) CDK16 CDK16_HUMAN (Q00536 ) CDK16_MOUSE (Q04735) CDK17 CDK17_HUMAN (Q00537 ) CDK17_MOUSE (Q8K0D0) CDK18 CDK18_HUMAN (Q07002 ) CDK18_MOUSE (Q04899) CDK19 CDK19_HUMAN (Q9BWU1 ) CDK19_MOUSE (Q8BWD8) CDK2 CDK2_HUMAN (P24941 ) CDK2_MOUSE (P97377) CDK20 CDK20_HUMAN (Q8IZL9 ) CDK20_MOUSE (Q9JHU3) CDK3 CDK3_HUMAN (Q00526 ) CDK3_MOUSE (Q80YP0) CDK4 CDK4_HUMAN (P11802 ) CDK4_MOUSE (P30285) CDK5 CDK5_HUMAN (Q00535 ) CDK5_MOUSE (P49615) CDK6 CDK6_HUMAN (Q00534 ) CDK6_MOUSE (Q64261) CDK7 CDK7_HUMAN (P50613 ) CDK7_MOUSE (Q03147) CDK8 CDK8_HUMAN (P49336 ) CDK8_MOUSE (Q8R3L8) CDK9 CDK9_HUMAN (P50750 ) CDK9_MOUSE (Q99J95) CDKL1 CDKL1_HUMAN (Q00532 ) CDKL1_MOUSE (Q8CEQ0) CDKL2 CDKL2_HUMAN (Q92772 ) CDKL2_MOUSE (Q9QUK0) CDKL3 CDKL3_HUMAN (Q8IVW4 ) CDKL3_MOUSE (Q8BLF2) CDKL4 CDKL4_HUMAN (Q5MAI5 ) CDKL4_MOUSE (Q3TZA2) CDKL5 CDKL5_HUMAN (O76039 ) CDKL5_MOUSE (Q3UTQ8) CILK1 CILK1_HUMAN (Q9UPZ9 ) CILK1_MOUSE (Q9JKV2) CLK1 CLK1_HUMAN (P49759 ) CLK1_MOUSE (P22518) CLK2 CLK2_HUMAN (P49760 ) CLK2_MOUSE (O35491) CLK3 CLK3_HUMAN (P49761 ) CLK3_MOUSE (O35492) CLK4 CLK4_HUMAN (Q9HAZ1 ) CLK4_MOUSE (O35493) DYRK1A DYR1A_HUMAN (Q13627 ) DYR1A_MOUSE (Q61214) DYRK1B DYR1B_HUMAN (Q9Y463 ) DYR1B_MOUSE (Q9Z188) DYRK2 DYRK2_HUMAN (Q92630 ) DYRK2_MOUSE (Q5U4C9) DYRK3 DYRK3_HUMAN (O43781 ) DYRK3_MOUSE (Q922Y0) DYRK4 DYRK4_HUMAN (Q9NR20 ) DYRK4_MOUSE (Q8BI55) GSK3A GSK3A_HUMAN (P49840 ) GSK3A_MOUSE (Q2NL51) GSK3B GSK3B_HUMAN (P49841 ) GSK3B_MOUSE (Q9WV60) HIPK1 HIPK1_HUMAN (Q86Z02 ) HIPK1_MOUSE (O88904) HIPK2 HIPK2_HUMAN (Q9H2X6 ) HIPK2_MOUSE (Q9QZR5) HIPK3 HIPK3_HUMAN (Q9H422 ) HIPK3_MOUSE (Q9ERH7) HIPK4 HIPK4_HUMAN (Q8NE63 ) HIPK4_MOUSE (Q3V016) MAK MAK_HUMAN (P20794 ) MAK_MOUSE (Q04859) MAPK1 MK01_HUMAN (P28482 ) MK01_MOUSE (P63085) MAPK10 MK10_HUMAN (P53779 ) MK10_MOUSE (Q61831) MAPK11 MK11_HUMAN (Q15759 ) MK11_MOUSE (Q9WUI1) MAPK12 MK12_HUMAN (P53778 ) MK12_MOUSE (O08911) MAPK13 MK13_HUMAN (O15264 ) MK13_MOUSE (Q9Z1B7) MAPK14 MK14_HUMAN (Q16539 ) MK14_MOUSE (P47811) MAPK15 MK15_HUMAN (Q8TD08 ) MK15_MOUSE (Q80Y86) MAPK3 MK03_HUMAN (P27361 ) MK03_MOUSE (Q63844) MAPK4 MK04_HUMAN (P31152 ) MK04_MOUSE (Q6P5G0) MAPK6 MK06_HUMAN (Q16659 ) MK06_MOUSE (Q61532) MAPK7 MK07_HUMAN (Q13164 ) MK07_MOUSE (Q9WVS8) MAPK8 MK08_HUMAN (P45983 ) MK08_MOUSE (Q91Y86) MAPK9 MK09_HUMAN (P45984 ) MK09_MOUSE (Q9WTU6) MOK MOK_HUMAN (Q9UQ07 ) MOK_MOUSE (Q9WVS4) NLK NLK_HUMAN (Q9UBE8 ) NLK_MOUSE (O54949) PRPF4B PRP4B_HUMAN (Q13523 ) PRP4B_MOUSE (Q61136) SRPK1 SRPK1_HUMAN (Q96SB4 ) SRPK1_MOUSE (O70551) SRPK2 SRPK2_HUMAN (P78362 ) SRPK2_MOUSE (O54781) SRPK3 SRPK3_HUMAN (Q9UPE1 ) SRPK3_MOUSE (Q9Z0G2) ================================= NEK Ser/Thr protein kinase family ================================= NEK1 NEK1_HUMAN (Q96PY6 ) NEK1_MOUSE (P51954) NEK10 NEK10_HUMAN (Q6ZWH5 ) NEK10_MOUSE (Q3UGM2) NEK11 NEK11_HUMAN (Q8NG66 ) NEK11_MOUSE (Q8C0Q4) NEK2 NEK2_HUMAN (P51955 ) NEK2_MOUSE (O35942) NEK3 NEK3_HUMAN (P51956 ) NEK3_MOUSE (Q9R0A5) NEK4 NEK4_HUMAN (P51957 ) NEK4_MOUSE (Q9Z1J2) NEK5 NEK5_HUMAN (Q6P3R8 ) NEK5_MOUSE (Q7TSC3) NEK6 NEK6_HUMAN (Q9HC98 ) NEK6_MOUSE (Q9ES70) NEK7 NEK7_HUMAN (Q8TDX7 ) NEK7_MOUSE (Q9ES74) NEK8 NEK8_HUMAN (Q86SG6 ) NEK8_MOUSE (Q91ZR4) NEK9 NEK9_HUMAN (Q8TD19 ) NEK9_MOUSE (Q8K1R7) ===================================================== RGC kinase: adenylyl cyclase class-4/guanylyl cyclase ===================================================== GUCY2C GUC2C_HUMAN (P25092 ) GUC2C_MOUSE (Q3UWA6) GUCY2D GUC2D_HUMAN (Q02846 ) GUC2D_MOUSE (A0A0U1) GUCY2F GUC2F_HUMAN (P51841 ) GUC2F_MOUSE (Q5SDA5) Gucy2e GUC2E_MOUSE (P52785) Gucy2g GUC2G_MOUSE (Q6TL19) NPR1 ANPRA_HUMAN (P16066 ) ANPRA_MOUSE (P18293) NPR2 ANPRB_HUMAN (P20594 ) ANPRB_MOUSE (Q6VVW5) ================================= STE Ser/Thr protein kinase family ================================= MAP2K1 MP2K1_HUMAN (Q02750 ) MP2K1_MOUSE (P31938) MAP2K2 MP2K2_HUMAN (P36507 ) MP2K2_MOUSE (Q63932) MAP2K3 MP2K3_HUMAN (P46734 ) MP2K3_MOUSE (O09110) MAP2K4 MP2K4_HUMAN (P45985 ) MP2K4_MOUSE (P47809) MAP2K5 MP2K5_HUMAN (Q13163 ) MP2K5_MOUSE (Q9WVS7) MAP2K6 MP2K6_HUMAN (P52564 ) MP2K6_MOUSE (P70236) MAP2K7 MP2K7_HUMAN (O14733 ) MP2K7_MOUSE (Q8CE90) MAP3K1 M3K1_HUMAN (Q13233 ) M3K1_MOUSE (P53349) MAP3K10 M3K10_HUMAN (Q02779 ) M3K10_MOUSE (Q66L42) MAP3K11 M3K11_HUMAN (Q16584 ) M3K11_MOUSE (Q80XI6) MAP3K12 M3K12_HUMAN (Q12852 ) M3K12_MOUSE (Q60700) MAP3K13 M3K13_HUMAN (O43283 ) M3K13_MOUSE (Q1HKZ5) MAP3K14 M3K14_HUMAN (Q99558 ) M3K14_MOUSE (Q9WUL6) MAP3K15 M3K15_HUMAN (Q6ZN16 ) M3K15_MOUSE (A2AQW0) MAP3K19 M3K19_HUMAN (Q56UN5 ) M3K19_MOUSE (E9Q3S4) MAP3K2 M3K2_HUMAN (Q9Y2U5 ) M3K2_MOUSE (Q61083) MAP3K20 M3K20_HUMAN (Q9NYL2 ) M3K20_MOUSE (Q9ESL4) MAP3K21 M3K21_HUMAN (Q5TCX8 ) M3K21_MOUSE (Q8VDG6) MAP3K3 M3K3_HUMAN (Q99759 ) M3K3_MOUSE (Q61084) MAP3K4 M3K4_HUMAN (Q9Y6R4 ) M3K4_MOUSE (O08648) MAP3K5 M3K5_HUMAN (Q99683 ) M3K5_MOUSE (O35099) MAP3K6 M3K6_HUMAN (O95382 ) M3K6_MOUSE (Q9WTR2) MAP3K7 M3K7_HUMAN (O43318 ) M3K7_MOUSE (Q62073) MAP3K8 M3K8_HUMAN (P41279 ) M3K8_MOUSE (Q07174) MAP3K9 M3K9_HUMAN (P80192 ) M3K9_MOUSE (Q3U1V8) MAP4K1 M4K1_HUMAN (Q92918 ) M4K1_MOUSE (P70218) MAP4K2 M4K2_HUMAN (Q12851 ) M4K2_MOUSE (Q61161) MAP4K3 M4K3_HUMAN (Q8IVH8 ) M4K3_MOUSE (Q99JP0) MAP4K4 M4K4_HUMAN (O95819 ) M4K4_MOUSE (P97820) MAP4K5 M4K5_HUMAN (Q9Y4K4 ) M4K5_MOUSE (Q8BPM2) MINK1 MINK1_HUMAN (Q8N4C8 ) MINK1_MOUSE (Q9JM52) MYO3A MYO3A_HUMAN (Q8NEV4 ) MYO3A_MOUSE (Q8K3H5) MYO3B MYO3B_HUMAN (Q8WXR4 ) MYO3B_MOUSE (Q1EG27) NRK NRK_HUMAN (Q7Z2Y5 ) NRK_MOUSE (Q9R0G8) OXSR1 OXSR1_HUMAN (O95747 ) OXSR1_MOUSE (Q6P9R2) PAK1 PAK1_HUMAN (Q13153 ) PAK1_MOUSE (O88643) PAK2 PAK2_HUMAN (Q13177 ) PAK2_MOUSE (Q8CIN4) PAK3 PAK3_HUMAN (O75914 ) PAK3_MOUSE (Q61036) PAK4 PAK4_HUMAN (O96013 ) PAK4_MOUSE (Q8BTW9) PAK5 PAK5_HUMAN (Q9P286 ) PAK5_MOUSE (Q8C015) PAK6 PAK6_HUMAN (Q9NQU5 ) PAK6_MOUSE (Q3ULB5) PBK TOPK_HUMAN (Q96KB5 ) TOPK_MOUSE (Q9JJ78) SLK SLK_HUMAN (Q9H2G2 ) SLK_MOUSE (O54988) STK10 STK10_HUMAN (O94804 ) STK10_MOUSE (O55098) STK24 STK24_HUMAN (Q9Y6E0 ) STK24_MOUSE (Q99KH8) STK25 STK25_HUMAN (O00506 ) STK25_MOUSE (Q9Z2W1) STK26 STK26_HUMAN (Q9P289 ) STK26_MOUSE (Q99JT2) STK3 STK3_HUMAN (Q13188 ) STK3_MOUSE (Q9JI10) STK39 STK39_HUMAN (Q9UEW8 ) STK39_MOUSE (Q9Z1W9) STK4 STK4_HUMAN (Q13043 ) STK4_MOUSE (Q9JI11) STRADA STRAA_HUMAN (Q7RTN6 ) STRAA_MOUSE (Q3UUJ4) STRADB STRAB_HUMAN (Q9C0K7 ) STRAB_MOUSE (Q8K4T3) TAOK1 TAOK1_HUMAN (Q7L7X3 ) TAOK1_MOUSE (Q5F2E8) TAOK2 TAOK2_HUMAN (Q9UL54 ) TAOK2_MOUSE (Q6ZQ29) TAOK3 TAOK3_HUMAN (Q9H2K8 ) TAOK3_MOUSE (Q8BYC6) TNIK TNIK_HUMAN (Q9UKE5 ) TNIK_MOUSE (P83510) ================================= TKL Ser/Thr protein kinase family ================================= ACVR1 ACVR1_HUMAN (Q04771 ) ACVR1_MOUSE (P37172) ACVR1B ACV1B_HUMAN (P36896 ) ACV1B_MOUSE (Q61271) ACVR1C ACV1C_HUMAN (Q8NER5 ) ACV1C_MOUSE (Q8K348) ACVR2A AVR2A_HUMAN (P27037 ) AVR2A_MOUSE (P27038) ACVR2B AVR2B_HUMAN (Q13705 ) AVR2B_MOUSE (P27040) ACVRL1 ACVL1_HUMAN (P37023 ) ACVL1_MOUSE (Q61288) AMHR2 AMHR2_HUMAN (Q16671 ) AMHR2_MOUSE (Q8K592) ANKK1 ANKK1_HUMAN (Q8NFD2 ) ANKK1_MOUSE (Q8BZ25) ARAF ARAF_HUMAN (P10398 ) ARAF_MOUSE (P04627) BMPR1A BMR1A_HUMAN (P36894 ) BMR1A_MOUSE (P36895) BMPR1B BMR1B_HUMAN (O00238 ) BMR1B_MOUSE (P36898) BMPR2 BMPR2_HUMAN (Q13873 ) BMPR2_MOUSE (O35607) BRAF BRAF_HUMAN (P15056 ) BRAF_MOUSE (P28028) ILK ILK_HUMAN (Q13418 ) ILK_MOUSE (O55222) IRAK1 IRAK1_HUMAN (P51617 ) IRAK1_MOUSE (Q62406) IRAK2 IRAK2_HUMAN (O43187 ) IRAK2_MOUSE (Q8CFA1) IRAK3 IRAK3_HUMAN (Q9Y616 ) IRAK3_MOUSE (Q8K4B2) IRAK4 IRAK4_HUMAN (Q9NWZ3 ) IRAK4_MOUSE (Q8R4K2) KSR1 KSR1_HUMAN (Q8IVT5 ) KSR1_MOUSE (Q61097) KSR2 KSR2_HUMAN (Q6VAB6 ) KSR2_MOUSE (Q3UVC0) LIMK1 LIMK1_HUMAN (P53667 ) LIMK1_MOUSE (P53668) LIMK2 LIMK2_HUMAN (P53671 ) LIMK2_MOUSE (O54785) LRRK1 LRRK1_HUMAN (Q38SD2 ) LRRK1_MOUSE (Q3UHC2) LRRK2 LRRK2_HUMAN (Q5S007 ) LRRK2_MOUSE (Q5S006) RAF1 RAF1_HUMAN (P04049 ) RAF1_MOUSE (Q99N57) RIPK1 RIPK1_HUMAN (Q13546 ) RIPK1_MOUSE (Q60855) RIPK2 RIPK2_HUMAN (O43353 ) RIPK2_MOUSE (P58801) RIPK3 RIPK3_HUMAN (Q9Y572 ) RIPK3_MOUSE (Q9QZL0) RIPK4 RIPK4_HUMAN (P57078 ) RIPK4_MOUSE (Q9ERK0) TESK1 TESK1_HUMAN (Q15569 ) TESK1_MOUSE (O70146) TESK2 TESK2_HUMAN (Q96S53 ) TESK2_MOUSE (Q8VCT9) TGFBR1 TGFR1_HUMAN (P36897 ) TGFR1_MOUSE (Q64729) TGFBR2 TGFR2_HUMAN (P37173 ) TGFR2_MOUSE (Q62312) TNNI3K TNI3K_HUMAN (Q59H18 ) TNI3K_MOUSE (Q5GIG6) ========================= Tyr protein kinase family ========================= AATK LMTK1_HUMAN (Q6ZMQ8 ) LMTK1_MOUSE (Q80YE4) ABL1 ABL1_HUMAN (P00519 ) ABL1_MOUSE (P00520) ABL2 ABL2_HUMAN (P42684 ) ABL2_MOUSE (Q4JIM5) ALK ALK_HUMAN (Q9UM73 ) ALK_MOUSE (P97793) AXL UFO_HUMAN (P30530 ) UFO_MOUSE (Q00993) BLK BLK_HUMAN (P51451 ) BLK_MOUSE (P16277) BMX BMX_HUMAN (P51813 ) BMX_MOUSE (P97504) BTK BTK_HUMAN (Q06187 ) BTK_MOUSE (P35991) CSF1R CSF1R_HUMAN (P07333 ) CSF1R_MOUSE (P09581) CSK CSK_HUMAN (P41240 ) CSK_MOUSE (P41241) DDR1 DDR1_HUMAN (Q08345 ) DDR1_MOUSE (Q03146) DDR2 DDR2_HUMAN (Q16832 ) DDR2_MOUSE (Q62371) EGFR EGFR_HUMAN (P00533 ) EGFR_MOUSE (Q01279) EPHA1 EPHA1_HUMAN (P21709 ) EPHA1_MOUSE (Q60750) EPHA10 EPHAA_HUMAN (Q5JZY3 ) EPHAA_MOUSE (Q8BYG9) EPHA2 EPHA2_HUMAN (P29317 ) EPHA2_MOUSE (Q03145) EPHA3 EPHA3_HUMAN (P29320 ) EPHA3_MOUSE (P29319) EPHA4 EPHA4_HUMAN (P54764 ) EPHA4_MOUSE (Q03137) EPHA5 EPHA5_HUMAN (P54756 ) EPHA5_MOUSE (Q60629) EPHA6 EPHA6_HUMAN (Q9UF33 ) EPHA6_MOUSE (Q62413) EPHA7 EPHA7_HUMAN (Q15375 ) EPHA7_MOUSE (Q61772) EPHA8 EPHA8_HUMAN (P29322 ) EPHA8_MOUSE (O09127) EPHB1 EPHB1_HUMAN (P54762 ) EPHB1_MOUSE (Q8CBF3) EPHB2 EPHB2_HUMAN (P29323 ) EPHB2_MOUSE (P54763) EPHB3 EPHB3_HUMAN (P54753 ) EPHB3_MOUSE (P54754) EPHB4 EPHB4_HUMAN (P54760 ) EPHB4_MOUSE (P54761) EPHB6 EPHB6_HUMAN (O15197 ) EPHB6_MOUSE (O08644) ERBB2 ERBB2_HUMAN (P04626 ) ERBB2_MOUSE (P70424) ERBB3 ERBB3_HUMAN (P21860 ) ERBB3_MOUSE (Q61526) ERBB4 ERBB4_HUMAN (Q15303 ) ERBB4_MOUSE (Q61527) FER FER_HUMAN (P16591 ) FER_MOUSE (P70451) FES FES_HUMAN (P07332 ) FES_MOUSE (P16879) FGFR1 FGFR1_HUMAN (P11362 ) FGFR1_MOUSE (P16092) FGFR2 FGFR2_HUMAN (P21802 ) FGFR2_MOUSE (P21803) FGFR3 FGFR3_HUMAN (P22607 ) FGFR3_MOUSE (Q61851) FGFR4 FGFR4_HUMAN (P22455 ) FGFR4_MOUSE (Q03142) FGR FGR_HUMAN (P09769 ) FGR_MOUSE (P14234) FLT1 VGFR1_HUMAN (P17948 ) VGFR1_MOUSE (P35969) FLT3 FLT3_HUMAN (P36888 ) FLT3_MOUSE (Q00342) FLT4 VGFR3_HUMAN (P35916 ) VGFR3_MOUSE (P35917) FRK FRK_HUMAN (P42685 ) FRK_MOUSE (Q922K9) FYN FYN_HUMAN (P06241 ) FYN_MOUSE (P39688) HCK HCK_HUMAN (P08631 ) HCK_MOUSE (P08103) IGF1R IGF1R_HUMAN (P08069 ) IGF1R_MOUSE (Q60751) INSR INSR_HUMAN (P06213 ) INSR_MOUSE (P15208) INSRR INSRR_HUMAN (P14616 ) INSRR_MOUSE (Q9WTL4) ITK ITK_HUMAN (Q08881 ) ITK_MOUSE (Q03526) JAK1 JAK1_HUMAN (P23458 ) JAK1_MOUSE (P52332) JAK2 JAK2_HUMAN (O60674 ) JAK2_MOUSE (Q62120) JAK3 JAK3_HUMAN (P52333 ) JAK3_MOUSE (Q62137) KDR VGFR2_HUMAN (P35968 ) VGFR2_MOUSE (P35918) KIT KIT_HUMAN (P10721 ) KIT_MOUSE (P05532) LCK LCK_HUMAN (P06239 ) LCK_MOUSE (P06240) LMTK2 LMTK2_HUMAN (Q8IWU2 ) LMTK2_MOUSE (Q3TYD6) LMTK3 LMTK3_HUMAN (Q96Q04 ) LMTK3_MOUSE (Q5XJV6) LTK LTK_HUMAN (P29376 ) LTK_MOUSE (P08923) LYN LYN_HUMAN (P07948 ) LYN_MOUSE (P25911) MATK MATK_HUMAN (P42679 ) MATK_MOUSE (P41242) MERTK MERTK_HUMAN (Q12866 ) MERTK_MOUSE (Q60805) MET MET_HUMAN (P08581 ) MET_MOUSE (P16056) MST1R RON_HUMAN (Q04912 ) RON_MOUSE (Q62190) MUSK MUSK_HUMAN (O15146 ) MUSK_MOUSE (Q61006) NTRK1 NTRK1_HUMAN (P04629 ) NTRK1_MOUSE (Q3UFB7) NTRK2 NTRK2_HUMAN (Q16620 ) NTRK2_MOUSE (P15209) NTRK3 NTRK3_HUMAN (Q16288 ) NTRK3_MOUSE (Q6VNS1) PDGFRA PGFRA_HUMAN (P16234 ) PGFRA_MOUSE (P26618) PDGFRB PGFRB_HUMAN (P09619 ) PGFRB_MOUSE (P05622) PTK2 FAK1_HUMAN (Q05397 ) FAK1_MOUSE (P34152) PTK2B FAK2_HUMAN (Q14289 ) FAK2_MOUSE (Q9QVP9) PTK6 PTK6_HUMAN (Q13882 ) PTK6_MOUSE (Q64434) PTK7 PTK7_HUMAN (Q13308 ) PTK7_MOUSE (Q8BKG3) RET RET_HUMAN (P07949 ) RET_MOUSE (P35546) ROR1 ROR1_HUMAN (Q01973 ) ROR1_MOUSE (Q9Z139) ROR2 ROR2_HUMAN (Q01974 ) ROR2_MOUSE (Q9Z138) ROS1 ROS1_HUMAN (P08922 ) ROS1_MOUSE (Q78DX7) RYK RYK_HUMAN (P34925 ) RYK_MOUSE (Q01887) SRC SRC_HUMAN (P12931 ) SRC_MOUSE (P05480) SRMS SRMS_HUMAN (Q9H3Y6 ) SRMS_MOUSE (Q62270) STYK1 STYK1_HUMAN (Q6J9G0 ) STYK1_MOUSE (Q6J9G1) SYK KSYK_HUMAN (P43405 ) KSYK_MOUSE (P48025) Smok1 SMOK1_MOUSE (Q9QYZ4) Smoktcr SMKTR_MOUSE (A2KF29) TEC TEC_HUMAN (P42680 ) TEC_MOUSE (P24604) TEK TIE2_HUMAN (Q02763 ) TIE2_MOUSE (Q02858) TIE1 TIE1_HUMAN (P35590 ) TIE1_MOUSE (Q06806) TNK1 TNK1_HUMAN (Q13470 ) TNK1_MOUSE (Q99ML2) TNK2 ACK1_HUMAN (Q07912 ) ACK1_MOUSE (O54967) TXK TXK_HUMAN (P42681 ) TXK_MOUSE (P42682) TYK2 TYK2_HUMAN (P29597 ) TYK2_MOUSE (Q9R117) TYRO3 TYRO3_HUMAN (Q06418 ) TYRO3_MOUSE (P55144) YES1 YES_HUMAN (P07947 ) YES_MOUSE (Q04736) ZAP70 ZAP70_HUMAN (P43403 ) ZAP70_MOUSE (P43404) ===== Other ===== AAK1 AAK1_HUMAN (Q2M2I8 ) AAK1_MOUSE (Q3UHJ0) AURKA AURKA_HUMAN (O14965 ) AURKA_MOUSE (P97477) AURKB AURKB_HUMAN (Q96GD4 ) AURKB_MOUSE (O70126) AURKC AURKC_HUMAN (Q9UQB9 ) AURKC_MOUSE (O88445) BMP2K BMP2K_HUMAN (Q9NSY1 ) BMP2K_MOUSE (Q91Z96) BUB1 BUB1_HUMAN (O43683 ) BUB1_MOUSE (O08901) BUB1B BUB1B_HUMAN (O60566 ) BUB1B_MOUSE (Q9Z1S0) CAMKK1 KKCC1_HUMAN (Q8N5S9 ) KKCC1_MOUSE (Q8VBY2) CAMKK2 KKCC2_HUMAN (Q96RR4 ) KKCC2_MOUSE (Q8C078) CDC7 CDC7_HUMAN (O00311 ) CDC7_MOUSE (Q9Z0H0) CHUK IKKA_HUMAN (O15111 ) IKKA_MOUSE (Q60680) CSNK2A1 CSK21_HUMAN (P68400 ) CSK21_MOUSE (Q60737) CSNK2A2 CSK22_HUMAN (P19784 ) CSK22_MOUSE (O54833) CSNK2A3 CSK23_HUMAN (Q8NEV1 ) DSTYK DUSTY_HUMAN (Q6XUX3 ) DUSTY_MOUSE (Q6XUX1) EIF2AK1 E2AK1_HUMAN (Q9BQI3 ) E2AK1_MOUSE (Q9Z2R9) EIF2AK2 E2AK2_HUMAN (P19525 ) E2AK2_MOUSE (Q03963) EIF2AK3 E2AK3_HUMAN (Q9NZJ5 ) E2AK3_MOUSE (Q9Z2B5) EIF2AK4 E2AK4_HUMAN (Q9P2K8 ) E2AK4_MOUSE (Q9QZ05) ERN1 ERN1_HUMAN (O75460 ) ERN1_MOUSE (Q9EQY0) ERN2 ERN2_HUMAN (Q76MJ5 ) ERN2_MOUSE (Q9Z2E3) GAK GAK_HUMAN (O14976 ) GAK_MOUSE (Q99KY4) HASPIN HASP_HUMAN (Q8TF76 ) HASP_MOUSE (Q9Z0R0) IKBKB IKKB_HUMAN (O14920 ) IKKB_MOUSE (O88351) IKBKE IKKE_HUMAN (Q14164 ) IKKE_MOUSE (Q9R0T8) MLKL MLKL_HUMAN (Q8NB16 ) MLKL_MOUSE (Q9D2Y4) MOS MOS_HUMAN (P00540 ) MOS_MOUSE (P00536) NRBP1 NRBP_HUMAN (Q9UHY1 ) NRBP_MOUSE (Q99J45) NRBP2 NRBP2_HUMAN (Q9NSY0 ) NRBP2_MOUSE (Q91V36) PAN3 PAN3_HUMAN (Q58A45 ) PAN3_MOUSE (Q640Q5) PDIK1L PDK1L_HUMAN (Q8N165 ) PDK1L_MOUSE (Q8QZR7) PEAK1 PEAK1_HUMAN (Q9H792 ) PEAK1_MOUSE (Q69Z38) PEAK3 PEAK3_HUMAN (Q6ZS72 ) PIK3R4 PI3R4_HUMAN (Q99570 ) PI3R4_MOUSE (Q8VD65) PINK1 PINK1_HUMAN (Q9BXM7 ) PINK1_MOUSE (Q99MQ3) PKDCC PKDCC_HUMAN (Q504Y2 ) PKDCC_MOUSE (Q5RJI4) PKMYT1 PMYT1_HUMAN (Q99640 ) PMYT1_MOUSE (Q9ESG9) PLK1 PLK1_HUMAN (P53350 ) PLK1_MOUSE (Q07832) PLK2 PLK2_HUMAN (Q9NYY3 ) PLK2_MOUSE (P53351) PLK3 PLK3_HUMAN (Q9H4B4 ) PLK3_MOUSE (Q60806) PLK4 PLK4_HUMAN (O00444 ) PLK4_MOUSE (Q64702) PLK5 PLK5_HUMAN (Q496M5 ) PLK5_MOUSE (Q4FZD7) POMK SG196_HUMAN (Q9H5K3 ) SG196_MOUSE (Q3TUA9) PRAG1 PRAG1_HUMAN (Q86YV5 ) PRAG1_MOUSE (Q571I4) PXK PXK_HUMAN (Q7Z7A4 ) PXK_MOUSE (Q8BX57) RNASEL RN5A_HUMAN (Q05823 ) RN5A_MOUSE (Q05921) RPS6KC1 KS6C1_HUMAN (Q96S38 ) KS6C1_MOUSE (Q8BLK9) RPS6KL1 RPKL1_HUMAN (Q9Y6S9 ) RPKL1_MOUSE (Q8R2S1) RSKR KS6R_HUMAN (Q96LW2 ) KS6R_MOUSE (Q5SYL1) SBK1 SBK1_HUMAN (Q52WX2 ) SBK1_MOUSE (Q8QZX0) SBK2 SBK2_HUMAN (P0C263 ) SBK2_MOUSE (P0C5K1) SBK3 SBK3_HUMAN (P0C264 ) SBK3_MOUSE (P0C5K0) SCYL1 SCYL1_HUMAN (Q96KG9 ) SCYL1_MOUSE (Q9EQC5) SCYL2 SCYL2_HUMAN (Q6P3W7 ) SCYL2_MOUSE (Q8CFE4) SCYL3 PACE1_HUMAN (Q8IZE3 ) PACE1_MOUSE (Q9DBQ7) STK16 STK16_HUMAN (O75716 ) STK16_MOUSE (O88697) STK31 STK31_HUMAN (Q9BXU1 ) STK31_MOUSE (Q99MW1) STK32A ST32A_HUMAN (Q8WU08 ) ST32A_MOUSE (Q8BGW6) STK32B ST32B_HUMAN (Q9NY57 ) ST32B_MOUSE (Q9JJX8) STK32C ST32C_HUMAN (Q86UX6 ) ST32C_MOUSE (Q8QZV4) STK35 STK35_HUMAN (Q8TDR2 ) STK35_MOUSE (Q80ZW0) STK36 STK36_HUMAN (Q9NRP7 ) STK36_MOUSE (Q69ZM6) STKLD1 STKL1_HUMAN (Q8NE28 ) STKL1_MOUSE (Q80YS9) TBCK TBCK_HUMAN (Q8TEA7 ) TBCK_MOUSE (Q8BM85) TBK1 TBK1_HUMAN (Q9UHD2 ) TBK1_MOUSE (Q9WUN2) TEX14 TEX14_HUMAN (Q8IWB6 ) TEX14_MOUSE (Q7M6U3) TLK1 TLK1_HUMAN (Q9UKI8 ) TLK1_MOUSE (Q8C0V0) TLK2 TLK2_HUMAN (Q86UE8 ) TLK2_MOUSE (O55047) TP53RK PRPK_HUMAN (Q96S44 ) TTK TTK_HUMAN (P33981 ) TTK_MOUSE (P35761) Tp53rkb PRPKB_MOUSE (Q99PW4) UHMK1 UHMK1_HUMAN (Q8TAS1 ) UHMK1_MOUSE (P97343) ULK1 ULK1_HUMAN (O75385 ) ULK1_MOUSE (O70405) ULK2 ULK2_HUMAN (Q8IYT8 ) ULK2_MOUSE (Q9QY01) ULK3 ULK3_HUMAN (Q6PHR2 ) ULK3_MOUSE (Q3U3Q1) ULK4 ULK4_HUMAN (Q96C45 ) ULK4_MOUSE (Q3V129) WEE1 WEE1_HUMAN (P30291 ) WEE1_MOUSE (P47810) WEE2 WEE2_HUMAN (P0C1S8 ) WEE2_MOUSE (Q66JT0) WNK1 WNK1_HUMAN (Q9H4A3 ) WNK1_MOUSE (P83741) WNK2 WNK2_HUMAN (Q9Y3S1 ) WNK2_MOUSE (Q3UH66) WNK3 WNK3_HUMAN (Q9BYP7 ) WNK3_MOUSE (Q80XP9) WNK4 WNK4_HUMAN (Q96J92 ) WNK4_MOUSE (Q80UE6) ==================================== Atypical: ADCK protein kinase family ==================================== ADCK1 ADCK1_HUMAN (Q86TW2 ) ADCK1_MOUSE (Q9D0L4) ADCK2 ADCK2_HUMAN (Q7Z695 ) ADCK2_MOUSE (Q6NSR3) ADCK5 ADCK5_HUMAN (Q3MIX3 ) ADCK5_MOUSE (Q80V03) COQ8A COQ8A_HUMAN (Q8NI60 ) COQ8A_MOUSE (Q60936) COQ8B COQ8B_HUMAN (Q96D53 ) COQ8B_MOUSE (Q566J8) ========================================== Atypical: Alpha-type protein kinase family ========================================== ALPK1 ALPK1_HUMAN (Q96QP1 ) ALPK1_MOUSE (Q9CXB8) ALPK2 ALPK2_HUMAN (Q86TB3 ) ALPK2_MOUSE (Q91ZB0) ALPK3 ALPK3_HUMAN (Q96L96 ) ALPK3_MOUSE (Q924C5) EEF2K EF2K_HUMAN (O00418 ) EF2K_MOUSE (O08796) TRPM6 TRPM6_HUMAN (Q9BX84 ) TRPM6_MOUSE (Q8CIR4) TRPM7 TRPM7_HUMAN (Q96QT4 ) TRPM7_MOUSE (Q923J1) ==================================== Atypical: FAST protein kinase family ==================================== FASTK FASTK_HUMAN (Q14296 ) FASTK_MOUSE (Q9JIX9) ========================================= Atypical: PDK/BCKDK protein kinase family ========================================= BCKDK BCKD_HUMAN (O14874 ) BCKD_MOUSE (O55028) PDK1 PDK1_HUMAN (Q15118 ) PDK1_MOUSE (Q8BFP9) PDK2 PDK2_HUMAN (Q15119 ) PDK2_MOUSE (Q9JK42) PDK3 PDK3_HUMAN (Q15120 ) PDK3_MOUSE (Q922H2) PDK4 PDK4_HUMAN (Q16654 ) PDK4_MOUSE (O70571) =============================== Atypical: PI3/PI4-kinase family =============================== ATM ATM_HUMAN (Q13315 ) ATM_MOUSE (Q62388) ATR ATR_HUMAN (Q13535 ) ATR_MOUSE (Q9JKK8) MTOR MTOR_HUMAN (P42345 ) MTOR_MOUSE (Q9JLN9) PIK3C2A P3C2A_HUMAN (O00443 ) P3C2A_MOUSE (Q61194) PIK3CA PK3CA_HUMAN (P42336 ) PK3CA_MOUSE (P42337) PIK3CB PK3CB_HUMAN (P42338 ) PK3CB_MOUSE (Q8BTI9) PIK3CD PK3CD_HUMAN (O00329 ) PK3CD_MOUSE (O35904) PIK3CG PK3CG_HUMAN (P48736 ) PK3CG_MOUSE (Q9JHG7) PRKDC PRKDC_HUMAN (P78527 ) PRKDC_MOUSE (P97313) SMG1 SMG1_HUMAN (Q96Q15 ) SMG1_MOUSE (Q8BKX6) ======================================== Atypical: RIO-type Ser/Thr kinase family ======================================== RIOK1 RIOK1_HUMAN (Q9BRS2 ) RIOK1_MOUSE (Q922Q2) RIOK2 RIOK2_HUMAN (Q9BVS4 ) RIOK2_MOUSE (Q9CQS5) RIOK3 RIOK3_HUMAN (O14730 ) RIOK3_MOUSE (Q9DBU3) -------------------------------------------------------------------------------- Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 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