format-version: 1.0
date: 27:09:2004 16:06
saved-by: gwg
auto-generated-by: DAG-Edit 1.418
default-namespace: gene_ontology
remark: cvs version: $Revision: 1.1 $
subsetdef: goslim_goa "GOA GO slim"
subsetdef: goslim_yeast "Yeast GO slim"
subsetdef: goslim_plant "Plant GO slim"
subsetdef: goslim_generic "Generic GO slim"
remark: GO_Slim_name:GOA and whole proteome analysis
remark: GO_Slim_authors: N.Mulder, M.Pruess
remark: GO_Slim_author_contact: goa@ebi.ac.uk
remark: GO_Slim_reference:Brief Bioinform.3:285-295

[Term]
id: GO:0000004
name: biological_process unknown
namespace: process
def: "Used for the annotation of gene products whose process is not known or cannot be inferred." [SGD:curators]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
subset: goslim_yeast
is_a: GO:0008150

[Term]
id: GO:0003674
name: molecular_function
namespace: function
def: "Elemental activities\, such as catalysis or binding\, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions." [GO:curators]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
subset: goslim_yeast

[Term]
id: GO:0003676
name: nucleic acid binding
namespace: function
def: "Interacting selectively with any nucleic acid." [GO:jl]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
is_a: GO:0005488

[Term]
id: GO:0003774
name: motor activity
namespace: function
def: "Catalysis of movement along a polymeric molecule such as a microfilament or microtubule\, coupled to the hydrolysis of a nucleoside triphosphate." [ISBN:0815316194, GO:mah]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
subset: goslim_yeast
is_a: GO:0003674

[Term]
id: GO:0003824
name: catalytic activity
namespace: function
def: "Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions\, the reactants are known as substrates\, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates\, and are usually composed wholly or largely of protein\, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic." [ISBN:0198506732]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
related_synonym: "enzyme activity" []
is_a: GO:0003674

[Term]
id: GO:0004386
name: helicase activity
namespace: function
def: "Catalysis of the unwinding of a DNA or RNA duplex." [ISBN:0198506732]
subset: goslim_goa
subset: goslim_yeast
xref_analog: Reactome:109879
xref_analog: Reactome:111307
xref_analog: Reactome:117604
xref_analog: Reactome:117605
xref_analog: Reactome:120688
xref_analog: Reactome:72598
xref_analog: Reactome:72599
is_a: GO:0003824

[Term]
id: GO:0004871
name: signal transducer activity
namespace: function
def: "Mediates the transfer of a signal from the outside to the inside of a cell by means other than the introduction of the signal molecule itself into the cell." [ISBN:0198506732, GO:jl]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
subset: goslim_yeast
is_a: GO:0003674

[Term]
id: GO:0004872
name: receptor activity
namespace: function
def: "Combining with an extracellular or intracellular messenger to initiate a change in cell activity." [GO:cb, ISBN:0198506732]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
is_a: GO:0004871

[Term]
id: GO:0005198
name: structural molecule activity
namespace: function
def: "The action of a molecule that contributes to the structural integrity of a complex or assembly within or outside a cell." [GO:mah]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
subset: goslim_yeast
is_a: GO:0003674

[Term]
id: GO:0005215
name: transporter activity
namespace: function
def: "Enables the directed movement of substances (such as macromolecules\, small molecules\, ions) into\, out of\, within or between cells." [GO:ma, SGD:df]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
subset: goslim_yeast
is_a: GO:0003674

[Term]
id: GO:0005386
name: carrier activity
namespace: function
def: "Catalysis of the transfer of a specific substance or related group of substances from one side of the membrane to the other." [ISBN:0198506732]
subset: goslim_goa
exact_synonym: "carrier type transporter" []
is_a: GO:0005215

[Term]
id: GO:0005488
name: binding
namespace: function
def: "The selective and stoichiometric interaction of a molecule with one or more specific sites on another molecule." [GO:cb, ISBN:0198506732]
comment: Note that ligand is being used in its broadest biological sense. For ligands that bind to signal transducing receptors\, consider the molecular function term 'receptor binding ; GO\:0005102' and its children.
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
synonym: "ligand" []
is_a: GO:0003674

[Term]
id: GO:0005489
name: electron transporter activity
namespace: function
def: "Enables the directed movement of electrons into\, out of\, within or between cells." [GO:ai]
subset: goslim_generic
subset: goslim_goa
is_a: GO:0005215

[Term]
id: GO:0005515
name: protein binding
namespace: function
def: "Interacting selectively with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules)." [GO:curators]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
subset: goslim_yeast
is_a: GO:0005488

[Term]
id: GO:0005554
name: molecular_function unknown
namespace: function
def: "Used for the annotation of gene products whose function is not known or cannot be inferred." [SGD:curators]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
subset: goslim_yeast
is_a: GO:0003674

[Term]
id: GO:0005575
name: cellular_component
namespace: component
def: "The part of a cell of which a gene product is a component; for purpose of GO includes the extracellular environment of cells; a gene product may be a component of one or more parts of a cell; this term includes gene products that are parts of macromolecular complexes\, by the definition that all members of a complex normally copurify under all except extreme conditions." [GO:curators]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
subset: goslim_yeast

[Term]
id: GO:0005576
name: extracellular
namespace: component
def: "The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite." [GO:curators]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
subset: goslim_yeast
is_a: GO:0005575

[Term]
id: GO:0005578
name: extracellular matrix
namespace: component
def: "A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity." [ISBN:0198547684]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
relationship: part_of GO:0005576

[Term]
id: GO:0005615
name: extracellular space
namespace: component
def: "That part of a multicellular organism outside the cells proper\, usually taken to be outside the plasma membranes\, and occupied by fluid." [ISBN:0198547684]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
relationship: part_of GO:0005576

[Term]
id: GO:0005622
name: intracellular
namespace: component
def: "The living contents of a cell; the matter contained within (but not including) the plasma membrane\, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm." [ISBN:0198506732]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
exact_synonym: "protoplasm" []
relationship: part_of GO:0005623

[Term]
id: GO:0005623
name: cell
namespace: component
def: "The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." [GO:curators]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
is_a: GO:0005575

[Term]
id: GO:0005634
name: nucleus
namespace: component
def: "A membrane-bounded organelle of eukaryotic cells that contains the chromosomes. It is the primary site of DNA replication and RNA synthesis in the cell." [GO:curators]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
subset: goslim_yeast
relationship: part_of GO:0005622

[Term]
id: GO:0005694
name: chromosome
namespace: component
def: "A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information." [ISBN:0198547684]
subset: goslim_generic
subset: goslim_goa
subset: goslim_yeast
relationship: part_of GO:0005622

[Term]
id: GO:0005737
name: cytoplasm
namespace: component
def: "All of the contents of a cell excluding the plasma membrane and nucleus\, but including other subcellular structures." [ISBN:0198547684]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
subset: goslim_yeast
relationship: part_of GO:0005622

[Term]
id: GO:0005941
name: unlocalized
namespace: component
def: "Used as a holding place for cellular components whose precise localization is\, as yet\, unknown\, or has not been determined by GO (the latter is the major reason for nodes to have this parent); this term should not be used for annotation of gene products." [FB:ma]
comment: See also the cellular component term 'cellular_component unknown ; GO\:0008372'.
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
is_a: GO:0005575

[Term]
id: GO:0006118
name: electron transport
namespace: process
def: "The transport of electrons from an electron donor to an electron acceptor." [http://cancerweb.ncl.ac.uk/]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
subset: goslim_yeast
exact_synonym: "electron transfer" []
is_a: GO:0008152

[Term]
id: GO:0006139
name: nucleobase, nucleoside, nucleotide and nucleic acid metabolism
namespace: process
def: "The chemical reactions and physical changes involving nucleobases\, nucleosides\, nucleotides and nucleic acids." [GO:ai]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
is_a: GO:0008152

[Term]
id: GO:0006519
name: amino acid and derivative metabolism
namespace: process
def: "The chemical reactions and physical changes involving amino acids\, organic acids containing one or more amino substituents\, and compounds derived from amino acids." [ISBN:0198506732]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
subset: goslim_yeast
is_a: GO:0008152

[Term]
id: GO:0006810
name: transport
namespace: process
def: "The directed movement of substances (such as macromolecules\, small molecules\, ions) into\, out of\, within or between cells." [GO:mah]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
subset: goslim_yeast
is_a: GO:0008151

[Term]
id: GO:0006928
name: cell motility
namespace: process
def: "Any process involved in the controlled movement of a cell." [GO:jl]
subset: goslim_goa
exact_synonym: "cell movement" []
is_a: GO:0050875

[Term]
id: GO:0006944
name: membrane fusion
namespace: process
def: "The joining of two lipid bilayers to form a single membrane." [GO:mah]
subset: goslim_goa
is_a: GO:0009987

[Term]
id: GO:0007154
name: cell communication
namespace: process
def: "Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell\, between a cell and an extracellular matrix\, or between a cell and any other aspect of its environment." [GO:mah]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
is_a: GO:0009987

[Term]
id: GO:0007275
name: development
namespace: process
def: "Biological processes specifically aimed at the progression of an organism over time from an initial condition (e.g. a zygote\, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." [WB:ems]
comment: Note that this term was 'developmental process'.
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
is_a: GO:0008150

[Term]
id: GO:0007582
name: physiological process
namespace: process
def: "Those processes specifically pertinent to the functioning of integrated living units\: cells\, tissues\, organs\, and organisms." [ISBN:0198506732, WB:ems]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
is_a: GO:0008150

[Term]
id: GO:0007610
name: behavior
namespace: process
def: "The specific actions or reactions of an organism in response to external or internal stimuli. Patterned activity of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions." [WB:ems, ISBN:0395448956]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
exact_synonym: "behaviour" []
is_a: GO:0008150

[Term]
id: GO:0008150
name: biological_process
namespace: process
def: "A phenomenon marked by changes that lead to a particular result\, mediated by one or more gene products." [GO:curators]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
subset: goslim_yeast

[Term]
id: GO:0008151
name: cell growth and/or maintenance
namespace: process
def: "Any process required for the survival and growth of a cell." [GO:mah]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
synonym: "cell physiology" []
is_a: GO:0050875

[Term]
id: GO:0008152
name: metabolism
namespace: process
def: "The totality of the chemical reactions and physical changes that occur in living organisms\, comprising anabolism and catabolism; may be qualified to mean the chemical reactions and physical processes undergone by a particular substance\, or class of substances\, in a living organism." [ISBN:0198547684]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
is_a: GO:0007582

[Term]
id: GO:0008219
name: cell death
namespace: process
def: "The specific activation or halting of processes within a cell so that its vital functions markedly cease\, rather than simply deteriorating gradually over time\, which culminates in cell death." [WB:ems]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
is_a: GO:0007582

[Term]
id: GO:0008372
name: cellular_component unknown
namespace: component
def: "Used for the annotation of gene products whose localization is not known or cannot be inferred." [FB:ma]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
subset: goslim_yeast
is_a: GO:0005575

[Term]
id: GO:0008402
name: aromatase activity
namespace: function
def: "Catalysis of the reaction\: R-H + reduced flavoprotein + O2 = R-OH + oxidized flavoprotein + H2O." [SP:P11511, GO:jl]
subset: goslim_goa
exact_synonym: "estrogen synthetase" []
narrow_synonym: "cytochrome P450 CYP19" []
is_a: GO:0003824

[Term]
id: GO:0008565
name: protein transporter activity
alt_id: GO:0015463
namespace: function
def: "Enables the directed movement of proteins into\, out of\, within or between cells." [ISBN:0198506732]
subset: goslim_goa
narrow_synonym: "enzyme transporter activity" []
is_a: GO:0005215

[Term]
id: GO:0008907
name: integrase activity
namespace: function
def: "Catalysis of the integration of lambdoid phage DNA during establishment\, probably by forming a transient DNA-protein link." [ISBN:0198506732]
subset: goslim_goa
is_a: GO:0003824

[Term]
id: GO:0009056
name: catabolism
namespace: process
def: "Any metabolic process involving the breakdown of complex substances into smaller products\, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism." [ISBN:0198547684]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
is_a: GO:0008152

[Term]
id: GO:0009058
name: biosynthesis
namespace: process
def: "The energy-requiring part of metabolism in which simpler substances are transformed into more complex ones\, as in growth and other biosynthetic processes." [ISBN:0198547684]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
exact_synonym: "anabolism" []
is_a: GO:0008152

[Term]
id: GO:0009405
name: pathogenesis
namespace: process
def: "The specific processes that generate the ability of an organism to cause disease in another." [GO:curators]
comment: Note that this term should not be used to annotate gene products that are involved in the host response to pathogenesis. It should only be used to annotate those gene products involved in the generation of pathogenesis by the pathogen itself.
subset: goslim_goa
synonym: "virulence" []
is_a: GO:0007582

[Term]
id: GO:0009986
name: cell surface
namespace: component
def: "The external part of the cell wall and/or cell membrane." [TAIR:sm, GO:jl]
subset: goslim_goa
synonym: "cell associated" []
synonym: "cell bound" []
relationship: part_of GO:0005623

[Term]
id: GO:0009987
name: cellular process
namespace: process
def: "Processes that are carried out at the cellular level\, but are not necessarily restricted to a single cell. For example\, cell communication occurs among more than one cell\, but occurs at the cellular level." [GO:curators]
subset: goslim_goa
subset: goslim_plant
is_a: GO:0008150

[Term]
id: GO:0015075
name: ion transporter activity
namespace: function
def: "Enables the directed movement of charged atoms or small charged molecules into\, out of\, within or between cells." [SGD:df]
subset: goslim_goa
is_a: GO:0005215

[Term]
id: GO:0015267
name: channel or pore class transporter activity
namespace: function
def: "Allows facilitated diffusion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without a carrier-mediated mechanism. They do not exhibit stereospecificity but may be specific for a particular molecular species or class of molecules." [TC:1.-.-.-.-]
subset: goslim_goa
exact_synonym: "channel/pore class transporter activity" []
xref_analog: TC:1.-.-.-.-
is_a: GO:0005215

[Term]
id: GO:0015646
name: permease activity
namespace: function
def: "Catalysis of the stereospecific transfer of a substrate across a biological membrane." [ISBN:0198506732, GO:ai]
subset: goslim_goa
is_a: GO:0005215

[Term]
id: GO:0016020
name: membrane
namespace: component
def: "Double layer of lipid molecules that encloses all cells\, and\, in eukaryotes\, many organelles; may be a single or double lipid bilayer\, also includes associated proteins." [GO:mah, ISBN:0815316194]
subset: goslim_goa
subset: goslim_plant
subset: goslim_yeast
relationship: part_of GO:0005623

[Term]
id: GO:0016209
name: antioxidant activity
namespace: function
def: "Inhibition of the reactions brought about by dioxygen (O2) or peroxides. Usually the antioxidant is effective because it can itself be more easily oxidized than the substance protected. The term is often applied to components that can trap free radicals\, thereby breaking the chain reaction that normally leads to extensive biological damage." [ISBN:0198506732]
subset: goslim_generic
subset: goslim_goa
is_a: GO:0003674

[Term]
id: GO:0016301
name: kinase activity
namespace: function
def: "Catalysis of the transfer of a phosphate group\, usually from ATP\, to a substrate molecule." [ISBN:0198506732]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
exact_synonym: "phosphokinase" []
xref_analog: Reactome:113431
xref_analog: Reactome:113433
xref_analog: Reactome:114246
xref_analog: Reactome:115027
xref_analog: Reactome:115715
xref_analog: Reactome:115932
xref_analog: Reactome:115944
xref_analog: Reactome:115947
xref_analog: Reactome:115951
xref_analog: Reactome:115974
xref_analog: Reactome:115991
xref_analog: Reactome:116605
xref_analog: Reactome:117491
xref_analog: Reactome:118310
xref_analog: Reactome:118568
xref_analog: Reactome:118583
xref_analog: Reactome:118586
xref_analog: Reactome:118589
xref_analog: Reactome:118596
xref_analog: Reactome:118617
xref_analog: Reactome:118965
xref_analog: Reactome:119356
xref_analog: Reactome:120179
xref_analog: Reactome:120930
xref_analog: Reactome:121183
xref_analog: Reactome:121192
xref_analog: Reactome:121216
xref_analog: Reactome:121239
xref_analog: Reactome:121274
xref_analog: Reactome:121543
xref_analog: Reactome:122577
xref_analog: Reactome:123125
xref_analog: Reactome:123301
xref_analog: Reactome:123309
xref_analog: Reactome:123312
xref_analog: Reactome:123316
xref_analog: Reactome:123331
xref_analog: Reactome:124636
xref_analog: Reactome:125197
xref_analog: Reactome:125408
xref_analog: Reactome:125423
xref_analog: Reactome:125426
xref_analog: Reactome:125441
xref_analog: Reactome:68385
xref_analog: Reactome:68401
xref_analog: Reactome:69194
xref_analog: Reactome:69222
xref_analog: Reactome:69246
xref_analog: Reactome:69254
xref_analog: Reactome:69603
xref_analog: Reactome:69607
xref_analog: Reactome:69716
xref_analog: Reactome:69904
xref_analog: Reactome:69913
xref_analog: Reactome:75047
xref_analog: Reactome:75051
xref_analog: Reactome:75052
xref_analog: Reactome:75053
xref_analog: Reactome:75054
xref_analog: Reactome:75225
xref_analog: Reactome:75371
xref_analog: Reactome:75808
xref_analog: Reactome:75819
xref_analog: Reactome:83536
is_a: GO:0003824

[Term]
id: GO:0016491
name: oxidoreductase activity
namespace: function
def: "Catalysis of an oxidation-reduction (redox) reaction\, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized\, while the other acts as hydrogen or electron acceptor and becomes reduced." [GO:curators]
comment: Note that enzymes of class EC\:1.97.-.- should also be annotated to this term.
subset: goslim_goa
subset: goslim_yeast
exact_synonym: "redox activity" []
xref_analog: EC:1.-.-.-
is_a: GO:0003824

[Term]
id: GO:0016740
name: transferase activity
namespace: function
def: "Catalysis of the transfer of a group\, e.g. a methyl group\, glycosyl group\, acyl group\, phosphorus-containing\, or other groups\, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2." [ISBN:0198506732]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
subset: goslim_yeast
xref_analog: EC:2.-.-.-
is_a: GO:0003824

[Term]
id: GO:0016787
name: hydrolase activity
namespace: function
def: "Catalysis of the hydrolysis of various bonds\, e.g. C-O\, C-N\, C-C\, phosphoric anhydride bonds\, etc. Hydrolase is the systematic name for any enzyme of EC class 3." [ISBN:0198506732]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
subset: goslim_yeast
xref_analog: EC:3.-.-.-
is_a: GO:0003824

[Term]
id: GO:0016829
name: lyase activity
namespace: function
def: "Catalysis of the cleavage of C-C\, C-O\, C-N and other bonds by other means than by hydrolysis or oxidation\, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction\, but only one in the other direction. When acting on the single substrate\, a molecule is eliminated and this generates either a new double bond or a new ring." [ISBN:0198547684, EC:4.-.-.-]
comment: Note that enzymes of class EC\:4.99.-.- should also be annotated to this term.
subset: goslim_goa
subset: goslim_yeast
xref_analog: EC:4.-.-.-
is_a: GO:0003824

[Term]
id: GO:0016853
name: isomerase activity
namespace: function
def: "Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5." [ISBN:0198506732]
comment: Note that enzymes of class EC\:5.99.-.- should also be annotated to this term.
subset: goslim_goa
subset: goslim_yeast
xref_analog: EC:5.-.-.-
is_a: GO:0003824

[Term]
id: GO:0016874
name: ligase activity
namespace: function
def: "Catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage\, usually in a nucleoside triphosphate. Ligase is the systematic name for any enzyme of EC class 6." [ISBN:0198506732]
subset: goslim_goa
subset: goslim_yeast
xref_analog: EC:6.-.-.-
is_a: GO:0003824

[Term]
id: GO:0030154
name: cell differentiation
namespace: process
def: "The process whereby relatively unspecialized cells\, e.g. embryonic or regenerative cells\, acquire specialized structural and/or functional features that characterize the cells\, tissues\, or organs of the mature organism or some other relatively stable phase of the organism's life history." [ISBN:0198506732]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
relationship: part_of GO:0007275
is_a: GO:0009987

[Term]
id: GO:0030188
name: chaperone regulator activity
namespace: function
def: "Modulates the activity of a molecular chaperone." [GO:mah]
subset: goslim_generic
subset: goslim_goa
is_a: GO:0003674

[Term]
id: GO:0030234
name: enzyme regulator activity
namespace: function
def: "Modulates the activity of an enzyme." [GO:mah]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
subset: goslim_yeast
exact_synonym: "enzyme modulator" []
is_a: GO:0003674

[Term]
id: GO:0030312
name: external encapsulating structure
namespace: component
def: "A structure that lies outside the plasma membrane and surrounds the entire cell." [GOC:curators]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
relationship: part_of GO:0005623

[Term]
id: GO:0030528
name: transcription regulator activity
namespace: function
def: "Plays a role in regulating transcription; may bind a promoter or enhancer DNA sequence or interact with a DNA-binding transcription factor." [GO:mah]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
subset: goslim_yeast
is_a: GO:0003674

[Term]
id: GO:0043062
name: extracellular structure organization and biogenesis
namespace: process
def: "The assembly and arrangement of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane\, and also covers the host cell environment outside an intracellular parasite." [GO:ai]
subset: goslim_goa
is_a: GO:0007582

[Term]
id: GO:0043170
name: macromolecule metabolism
namespace: process
def: "The chemical reactions and physical changes involving macromolecules\, large molecules including proteins\, nucleic acids and carbohydrates." [GO:jl ""]
subset: goslim_goa
is_a: GO:0008152

[Term]
id: GO:0045182
name: translation regulator activity
namespace: function
def: "Any substance involved in the initiation\, activation\, perpetuation\, repression or termination of polypeptide synthesis at the ribosome." [GO:ai]
subset: goslim_generic
subset: goslim_goa
subset: goslim_plant
subset: goslim_yeast
is_a: GO:0003674

[Term]
id: GO:0046903
name: secretion
namespace: process
def: "The regulated release of a substance by a cell or group of cells." [GO:ai]
subset: goslim_goa
is_a: GO:0007582

[Term]
id: GO:0050789
name: regulation of biological process
namespace: process
def: "Any process that modulates the frequency\, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression\, protein modification or interaction with a protein or substrate molecule." [GO:ai, GO:curators]
subset: goslim_goa
broad_synonym: "regulation" []
is_a: GO:0008150

[Term]
id: GO:0050875
name: cellular physiological process
namespace: process
def: "The processes pertinent to the integrated function of a cell." [MGI:dph, ISBN:0721619908]
subset: goslim_goa
is_a: GO:0007582
is_a: GO:0009987

[Term]
id: GO:0050896
name: response to stimulus
namespace: process
def: "A change in state or activity of a cell or organism (in terms of movement\, secretion\, enzyme production\, gene expression\, etc.) as a result of the perception of a stimulus." [GO:ai]
subset: goslim_goa
is_a: GO:0007582

[Typedef]
id: part_of
name: Part of