#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9H173	uniprotkb:Q9H173	intact:EBI-2840325|uniprotkb:Q8N2L3|uniprotkb:D3DQC2|ensembl:ENSP00000265195|ensembl:ENSP00000378294	intact:EBI-2840325|uniprotkb:Q8N2L3|uniprotkb:D3DQC2|ensembl:ENSP00000265195|ensembl:ENSP00000378294	psi-mi:sil1_human(display_long)|uniprotkb:SIL1(gene name)|psi-mi:SIL1(display_short)|uniprotkb:BiP-associated protein(gene name synonym)|uniprotkb:UNQ545/PRO836(orf name)	psi-mi:sil1_human(display_long)|uniprotkb:SIL1(gene name)|psi-mi:SIL1(display_short)|uniprotkb:BiP-associated protein(gene name synonym)|uniprotkb:UNQ545/PRO836(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Gatz et al. (2018)	pubmed:31258504|imex:IM-28632	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26610034|imex:IM-28632-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001032722.1|refseq:NP_071909.1|ensembl:ENSG00000120725(gene)|ensembl:ENST00000265195(transcript)|ensembl:ENST00000394817(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9H173|rcsb pdb:6LBN|rcsb pdb:6LEY	refseq:NP_001032722.1|refseq:NP_071909.1|ensembl:ENSG00000120725(gene)|ensembl:ENST00000265195(transcript)|ensembl:ENST00000394817(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9H173|rcsb pdb:6LBN|rcsb pdb:6LEY	-	-	-	figure legend:2c|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2021/01/15	2021/02/01	rogid:ACM0iWdu137zhE8pXo8ckj1opfg9606	rogid:ACM0iWdu137zhE8pXo8ckj1opfg9606	rigid:O2QJX+I03WMwDTEq5qBm/Ikzzyg	false	calmodulin binding peptide plus protein a tag:c-c|mutation with no effect:92-92(rs149242794)	ha tag:c-c|mutation with no effect:92-92(rs149242794)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9H173	uniprotkb:Q9H173	intact:EBI-2840325|uniprotkb:Q8N2L3|uniprotkb:D3DQC2|ensembl:ENSP00000265195|ensembl:ENSP00000378294	intact:EBI-2840325|uniprotkb:Q8N2L3|uniprotkb:D3DQC2|ensembl:ENSP00000265195|ensembl:ENSP00000378294	psi-mi:sil1_human(display_long)|uniprotkb:SIL1(gene name)|psi-mi:SIL1(display_short)|uniprotkb:BiP-associated protein(gene name synonym)|uniprotkb:UNQ545/PRO836(orf name)	psi-mi:sil1_human(display_long)|uniprotkb:SIL1(gene name)|psi-mi:SIL1(display_short)|uniprotkb:BiP-associated protein(gene name synonym)|uniprotkb:UNQ545/PRO836(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Gatz et al. (2018)	pubmed:31258504|imex:IM-28632	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26610177|imex:IM-28632-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001032722.1|refseq:NP_071909.1|ensembl:ENSG00000120725(gene)|ensembl:ENST00000265195(transcript)|ensembl:ENST00000394817(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9H173|rcsb pdb:6LBN|rcsb pdb:6LEY	refseq:NP_001032722.1|refseq:NP_071909.1|ensembl:ENSG00000120725(gene)|ensembl:ENST00000265195(transcript)|ensembl:ENST00000394817(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9H173|rcsb pdb:6LBN|rcsb pdb:6LEY	-	-	-	figure legend:2d|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2021/01/15	2021/02/01	rogid:ACM0iWdu137zhE8pXo8ckj1opfg9606	rogid:ACM0iWdu137zhE8pXo8ckj1opfg9606	rigid:O2QJX+I03WMwDTEq5qBm/Ikzzyg	false	calmodulin binding peptide plus protein a tag:c-c|mutation with no effect:132-132(rs61745568)	ha tag:c-c|mutation with no effect:132-132(rs61745568)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9H173	uniprotkb:Q9H173	intact:EBI-2840325|uniprotkb:Q8N2L3|uniprotkb:D3DQC2|ensembl:ENSP00000265195|ensembl:ENSP00000378294	intact:EBI-2840325|uniprotkb:Q8N2L3|uniprotkb:D3DQC2|ensembl:ENSP00000265195|ensembl:ENSP00000378294	psi-mi:sil1_human(display_long)|uniprotkb:SIL1(gene name)|psi-mi:SIL1(display_short)|uniprotkb:BiP-associated protein(gene name synonym)|uniprotkb:UNQ545/PRO836(orf name)	psi-mi:sil1_human(display_long)|uniprotkb:SIL1(gene name)|psi-mi:SIL1(display_short)|uniprotkb:BiP-associated protein(gene name synonym)|uniprotkb:UNQ545/PRO836(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Gatz et al. (2018)	pubmed:31258504|imex:IM-28632	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26610192|imex:IM-28632-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001032722.1|refseq:NP_071909.1|ensembl:ENSG00000120725(gene)|ensembl:ENST00000265195(transcript)|ensembl:ENST00000394817(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9H173|rcsb pdb:6LBN|rcsb pdb:6LEY	refseq:NP_001032722.1|refseq:NP_071909.1|ensembl:ENSG00000120725(gene)|ensembl:ENST00000265195(transcript)|ensembl:ENST00000394817(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9H173|rcsb pdb:6LBN|rcsb pdb:6LEY	-	-	-	figure legend:2b|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2021/01/15	2021/02/01	rogid:ACM0iWdu137zhE8pXo8ckj1opfg9606	rogid:ACM0iWdu137zhE8pXo8ckj1opfg9606	rigid:O2QJX+I03WMwDTEq5qBm/Ikzzyg	false	ha tag:c-c	calmodulin binding peptide plus protein a tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9H173	uniprotkb:Q9H173	intact:EBI-2840325|uniprotkb:Q8N2L3|uniprotkb:D3DQC2|ensembl:ENSP00000265195|ensembl:ENSP00000378294	intact:EBI-2840325|uniprotkb:Q8N2L3|uniprotkb:D3DQC2|ensembl:ENSP00000265195|ensembl:ENSP00000378294	psi-mi:sil1_human(display_long)|uniprotkb:SIL1(gene name)|psi-mi:SIL1(display_short)|uniprotkb:BiP-associated protein(gene name synonym)|uniprotkb:UNQ545/PRO836(orf name)	psi-mi:sil1_human(display_long)|uniprotkb:SIL1(gene name)|psi-mi:SIL1(display_short)|uniprotkb:BiP-associated protein(gene name synonym)|uniprotkb:UNQ545/PRO836(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Gatz et al. (2018)	pubmed:31258504|imex:IM-28632	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26610463|imex:IM-28632-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001032722.1|refseq:NP_071909.1|ensembl:ENSG00000120725(gene)|ensembl:ENST00000265195(transcript)|ensembl:ENST00000394817(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9H173|rcsb pdb:6LBN|rcsb pdb:6LEY	refseq:NP_001032722.1|refseq:NP_071909.1|ensembl:ENSG00000120725(gene)|ensembl:ENST00000265195(transcript)|ensembl:ENST00000394817(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9H173|rcsb pdb:6LBN|rcsb pdb:6LEY	-	-	-	figure legend:2e|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2021/01/15	2021/02/01	rogid:ACM0iWdu137zhE8pXo8ckj1opfg9606	rogid:ACM0iWdu137zhE8pXo8ckj1opfg9606	rigid:O2QJX+I03WMwDTEq5qBm/Ikzzyg	false	calmodulin binding peptide plus protein a tag:c-c|mutation disrupting interaction strength:231-232	ha tag:c-c|mutation disrupting interaction strength:231-232(rs61745568)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9H173	uniprotkb:Q9H173	intact:EBI-2840325|uniprotkb:Q8N2L3|uniprotkb:D3DQC2|ensembl:ENSP00000265195|ensembl:ENSP00000378294	intact:EBI-2840325|uniprotkb:Q8N2L3|uniprotkb:D3DQC2|ensembl:ENSP00000265195|ensembl:ENSP00000378294	psi-mi:sil1_human(display_long)|uniprotkb:SIL1(gene name)|psi-mi:SIL1(display_short)|uniprotkb:BiP-associated protein(gene name synonym)|uniprotkb:UNQ545/PRO836(orf name)	psi-mi:sil1_human(display_long)|uniprotkb:SIL1(gene name)|psi-mi:SIL1(display_short)|uniprotkb:BiP-associated protein(gene name synonym)|uniprotkb:UNQ545/PRO836(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Gatz et al. (2018)	pubmed:31258504|imex:IM-28632	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26610502|imex:IM-28632-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001032722.1|refseq:NP_071909.1|ensembl:ENSG00000120725(gene)|ensembl:ENST00000265195(transcript)|ensembl:ENST00000394817(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9H173|rcsb pdb:6LBN|rcsb pdb:6LEY	refseq:NP_001032722.1|refseq:NP_071909.1|ensembl:ENSG00000120725(gene)|ensembl:ENST00000265195(transcript)|ensembl:ENST00000394817(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9H173|rcsb pdb:6LBN|rcsb pdb:6LEY	-	-	-	figure legend:2f|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2021/01/15	2021/02/01	rogid:ACM0iWdu137zhE8pXo8ckj1opfg9606	rogid:ACM0iWdu137zhE8pXo8ckj1opfg9606	rigid:O2QJX+I03WMwDTEq5qBm/Ikzzyg	false	calmodulin binding peptide plus protein a tag:c-c|mutation with no effect:312-312	ha tag:c-c|mutation with no effect:312-312(rs61745568)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9H173	uniprotkb:Q9H173	intact:EBI-2840325|uniprotkb:Q8N2L3|uniprotkb:D3DQC2|ensembl:ENSP00000265195|ensembl:ENSP00000378294	intact:EBI-2840325|uniprotkb:Q8N2L3|uniprotkb:D3DQC2|ensembl:ENSP00000265195|ensembl:ENSP00000378294	psi-mi:sil1_human(display_long)|uniprotkb:SIL1(gene name)|psi-mi:SIL1(display_short)|uniprotkb:BiP-associated protein(gene name synonym)|uniprotkb:UNQ545/PRO836(orf name)	psi-mi:sil1_human(display_long)|uniprotkb:SIL1(gene name)|psi-mi:SIL1(display_short)|uniprotkb:BiP-associated protein(gene name synonym)|uniprotkb:UNQ545/PRO836(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Gatz et al. (2018)	pubmed:31258504|imex:IM-28632	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26610523|imex:IM-28632-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001032722.1|refseq:NP_071909.1|ensembl:ENSG00000120725(gene)|ensembl:ENST00000265195(transcript)|ensembl:ENST00000394817(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9H173|rcsb pdb:6LBN|rcsb pdb:6LEY	refseq:NP_001032722.1|refseq:NP_071909.1|ensembl:ENSG00000120725(gene)|ensembl:ENST00000265195(transcript)|ensembl:ENST00000394817(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9H173|rcsb pdb:6LBN|rcsb pdb:6LEY	-	-	-	figure legend:2g|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2021/01/15	2021/02/01	rogid:ACM0iWdu137zhE8pXo8ckj1opfg9606	rogid:ACM0iWdu137zhE8pXo8ckj1opfg9606	rigid:O2QJX+I03WMwDTEq5qBm/Ikzzyg	false	calmodulin binding peptide plus protein a tag:c-c|mutation with no effect:457-457	ha tag:c-c|mutation with no effect:457-457	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9H173	uniprotkb:P38646	intact:EBI-2840325|uniprotkb:Q8N2L3|uniprotkb:D3DQC2|ensembl:ENSP00000265195|ensembl:ENSP00000378294	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	psi-mi:sil1_human(display_long)|uniprotkb:SIL1(gene name)|psi-mi:SIL1(display_short)|uniprotkb:BiP-associated protein(gene name synonym)|uniprotkb:UNQ545/PRO836(orf name)	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Gatz et al. (2018)	pubmed:31258504|imex:IM-28632	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26610806|imex:IM-28632-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001032722.1|refseq:NP_071909.1|ensembl:ENSG00000120725(gene)|ensembl:ENST00000265195(transcript)|ensembl:ENST00000394817(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9H173|rcsb pdb:6LBN|rcsb pdb:6LEY	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N	intact:EBI-26686771(see-also)|intact:EBI-26686718(see-also)|intact:EBI-26686730(see-also)|intact:EBI-26686742(see-also)|intact:EBI-26686756(see-also)	-	-	figure legend:5a|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2021/01/15	2021/02/24	rogid:ACM0iWdu137zhE8pXo8ckj1opfg9606	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	rigid:uUFXl3YRmAG54LDzQJsV2/JYeLc	false	calmodulin binding peptide plus protein a tag:c-c|mutation with complex effect:92-92|mutation with complex effect:132-132|mutation with complex effect:231-232|mutation with complex effect:312-312|mutation with complex effect:457-457	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q9H173	uniprotkb:P11021	intact:EBI-2840325|uniprotkb:Q8N2L3|uniprotkb:D3DQC2|ensembl:ENSP00000265195|ensembl:ENSP00000378294	intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61	psi-mi:sil1_human(display_long)|uniprotkb:SIL1(gene name)|psi-mi:SIL1(display_short)|uniprotkb:BiP-associated protein(gene name synonym)|uniprotkb:UNQ545/PRO836(orf name)	psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Gatz et al. (2018)	pubmed:31258504|imex:IM-28632	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26610806|imex:IM-28632-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001032722.1|refseq:NP_071909.1|ensembl:ENSG00000120725(gene)|ensembl:ENST00000265195(transcript)|ensembl:ENST00000394817(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9H173|rcsb pdb:6LBN|rcsb pdb:6LEY	ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N	intact:EBI-26686771(see-also)|intact:EBI-26686718(see-also)|intact:EBI-26686730(see-also)|intact:EBI-26686742(see-also)|intact:EBI-26686756(see-also)	-	-	figure legend:5a|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2021/01/15	2021/02/24	rogid:ACM0iWdu137zhE8pXo8ckj1opfg9606	rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606	rigid:uUFXl3YRmAG54LDzQJsV2/JYeLc	false	calmodulin binding peptide plus protein a tag:c-c|mutation with complex effect:92-92|mutation with complex effect:132-132|mutation with complex effect:231-232|mutation with complex effect:312-312|mutation with complex effect:457-457	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q9H173	uniprotkb:Q8NBT0	intact:EBI-2840325|uniprotkb:Q8N2L3|uniprotkb:D3DQC2|ensembl:ENSP00000265195|ensembl:ENSP00000378294	intact:EBI-2557132|uniprotkb:A4FUW4|uniprotkb:E9PFC6|uniprotkb:Q96IK6|uniprotkb:Q2TAK6|uniprotkb:Q0VDF8|uniprotkb:Q9UFJ8|ensembl:ENSP00000296484	psi-mi:sil1_human(display_long)|uniprotkb:SIL1(gene name)|psi-mi:SIL1(display_short)|uniprotkb:BiP-associated protein(gene name synonym)|uniprotkb:UNQ545/PRO836(orf name)	psi-mi:poc1a_human(display_long)|uniprotkb:WDR51A(gene name synonym)|uniprotkb:WD repeat-containing protein 51A(gene name synonym)|uniprotkb:POC1A(gene name)|psi-mi:POC1A(display_short)|uniprotkb:Pix2(gene name synonym)|uniprotkb:Proteome of centriole protein 1A(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Gatz et al. (2018)	pubmed:31258504|imex:IM-28632	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26610806|imex:IM-28632-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001032722.1|refseq:NP_071909.1|ensembl:ENSG00000120725(gene)|ensembl:ENST00000265195(transcript)|ensembl:ENST00000394817(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9H173|rcsb pdb:6LBN|rcsb pdb:6LEY	ensembl:ENSG00000164087(gene)|ensembl:ENST00000296484(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0030030"(cell projection organization)|go:"GO:0036064"(ciliary basal body)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|refseq:NP_001155052.1|refseq:NP_001155053.1|refseq:NP_056241.3	intact:EBI-26686771(see-also)|intact:EBI-26686718(see-also)|intact:EBI-26686730(see-also)|intact:EBI-26686742(see-also)|intact:EBI-26686756(see-also)	-	-	figure legend:5a|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2021/01/15	2021/02/24	rogid:ACM0iWdu137zhE8pXo8ckj1opfg9606	rogid:McHLLJ/7U4ZfJoqMeCmDrxuGOpU9606	rigid:uUFXl3YRmAG54LDzQJsV2/JYeLc	false	calmodulin binding peptide plus protein a tag:c-c|mutation with complex effect:92-92|mutation with complex effect:132-132|mutation with complex effect:231-232|mutation with complex effect:312-312|mutation with complex effect:457-457	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q9H173	uniprotkb:P04632	intact:EBI-2840325|uniprotkb:Q8N2L3|uniprotkb:D3DQC2|ensembl:ENSP00000265195|ensembl:ENSP00000378294	intact:EBI-711828|uniprotkb:Q8WTX3|uniprotkb:Q96EW0|uniprotkb:A8K0P1|ensembl:ENSP00000246533|ensembl:ENSP00000464849	psi-mi:sil1_human(display_long)|uniprotkb:SIL1(gene name)|psi-mi:SIL1(display_short)|uniprotkb:BiP-associated protein(gene name synonym)|uniprotkb:UNQ545/PRO836(orf name)	psi-mi:cpns1_human(display_long)|uniprotkb:Calcium-dependent protease small subunit 1(gene name synonym)|uniprotkb:Calcium-dependent protease small subunit(gene name synonym)|uniprotkb:Calpain regulatory subunit(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase small subunit(gene name synonym)|uniprotkb:CAPNS1(gene name)|psi-mi:CAPNS1(display_short)|uniprotkb:CAPN4(gene name synonym)|uniprotkb:CAPNS(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Gatz et al. (2018)	pubmed:31258504|imex:IM-28632	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26610806|imex:IM-28632-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001032722.1|refseq:NP_071909.1|ensembl:ENSG00000120725(gene)|ensembl:ENST00000265195(transcript)|ensembl:ENST00000394817(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9H173|rcsb pdb:6LBN|rcsb pdb:6LEY	ensembl:ENSG00000126247(gene)|ensembl:ENST00000246533(transcript)|ensembl:ENST00000588815(transcript)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR029642|mint:P04632|rcsb pdb:1KFU|rcsb pdb:1KFX|rcsb pdb:4PHJ|rcsb pdb:4PHK|rcsb pdb:4PHM|rcsb pdb:4WQ2|rcsb pdb:4WQ3|rcsb pdb:5D69|rcsb pdb:6QLB|reactome:R-HSA-1474228|reactome:R-HSA-6809371|reactome:R-HSA-8862803|refseq:NP_001003962.1|refseq:NP_001740.1|refseq:NP_001289561.1|refseq:NP_001289562.1|refseq:XP_005259352.1|refseq:XP_005259353.1	intact:EBI-26686771(see-also)|intact:EBI-26686718(see-also)|intact:EBI-26686730(see-also)|intact:EBI-26686742(see-also)|intact:EBI-26686756(see-also)	-	-	figure legend:5a|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2021/01/15	2021/02/24	rogid:ACM0iWdu137zhE8pXo8ckj1opfg9606	rogid:siQugDvaWq0YjOr8qOCf0BsRRKs9606	rigid:uUFXl3YRmAG54LDzQJsV2/JYeLc	false	calmodulin binding peptide plus protein a tag:c-c|mutation with complex effect:92-92|mutation with complex effect:132-132|mutation with complex effect:231-232|mutation with complex effect:312-312|mutation with complex effect:457-457	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q9H173	uniprotkb:Q8NBT0	intact:EBI-2840325|uniprotkb:Q8N2L3|uniprotkb:D3DQC2|ensembl:ENSP00000265195|ensembl:ENSP00000378294	intact:EBI-2557132|uniprotkb:A4FUW4|uniprotkb:E9PFC6|uniprotkb:Q96IK6|uniprotkb:Q2TAK6|uniprotkb:Q0VDF8|uniprotkb:Q9UFJ8|ensembl:ENSP00000296484	psi-mi:sil1_human(display_long)|uniprotkb:SIL1(gene name)|psi-mi:SIL1(display_short)|uniprotkb:BiP-associated protein(gene name synonym)|uniprotkb:UNQ545/PRO836(orf name)	psi-mi:poc1a_human(display_long)|uniprotkb:WDR51A(gene name synonym)|uniprotkb:WD repeat-containing protein 51A(gene name synonym)|uniprotkb:POC1A(gene name)|psi-mi:POC1A(display_short)|uniprotkb:Pix2(gene name synonym)|uniprotkb:Proteome of centriole protein 1A(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Gatz et al. (2018)	pubmed:31258504|imex:IM-28632	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26686718|imex:IM-28632-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001032722.1|refseq:NP_071909.1|ensembl:ENSG00000120725(gene)|ensembl:ENST00000265195(transcript)|ensembl:ENST00000394817(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9H173|rcsb pdb:6LBN|rcsb pdb:6LEY	ensembl:ENSG00000164087(gene)|ensembl:ENST00000296484(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0030030"(cell projection organization)|go:"GO:0036064"(ciliary basal body)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|refseq:NP_001155052.1|refseq:NP_001155053.1|refseq:NP_056241.3	intact:EBI-26610806(see-also)	-	-	figure legend:5a|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2021/01/15	2021/02/24	rogid:ACM0iWdu137zhE8pXo8ckj1opfg9606	rogid:McHLLJ/7U4ZfJoqMeCmDrxuGOpU9606	rigid:uUFXl3YRmAG54LDzQJsV2/JYeLc	false	calmodulin binding peptide plus protein a tag:c-c|mutation:92-92	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q9H173	uniprotkb:P04632	intact:EBI-2840325|uniprotkb:Q8N2L3|uniprotkb:D3DQC2|ensembl:ENSP00000265195|ensembl:ENSP00000378294	intact:EBI-711828|uniprotkb:Q8WTX3|uniprotkb:Q96EW0|uniprotkb:A8K0P1|ensembl:ENSP00000246533|ensembl:ENSP00000464849	psi-mi:sil1_human(display_long)|uniprotkb:SIL1(gene name)|psi-mi:SIL1(display_short)|uniprotkb:BiP-associated protein(gene name synonym)|uniprotkb:UNQ545/PRO836(orf name)	psi-mi:cpns1_human(display_long)|uniprotkb:Calcium-dependent protease small subunit 1(gene name synonym)|uniprotkb:Calcium-dependent protease small subunit(gene name synonym)|uniprotkb:Calpain regulatory subunit(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase small subunit(gene name synonym)|uniprotkb:CAPNS1(gene name)|psi-mi:CAPNS1(display_short)|uniprotkb:CAPN4(gene name synonym)|uniprotkb:CAPNS(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Gatz et al. (2018)	pubmed:31258504|imex:IM-28632	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26686718|imex:IM-28632-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001032722.1|refseq:NP_071909.1|ensembl:ENSG00000120725(gene)|ensembl:ENST00000265195(transcript)|ensembl:ENST00000394817(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9H173|rcsb pdb:6LBN|rcsb pdb:6LEY	ensembl:ENSG00000126247(gene)|ensembl:ENST00000246533(transcript)|ensembl:ENST00000588815(transcript)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR029642|mint:P04632|rcsb pdb:1KFU|rcsb pdb:1KFX|rcsb pdb:4PHJ|rcsb pdb:4PHK|rcsb pdb:4PHM|rcsb pdb:4WQ2|rcsb pdb:4WQ3|rcsb pdb:5D69|rcsb pdb:6QLB|reactome:R-HSA-1474228|reactome:R-HSA-6809371|reactome:R-HSA-8862803|refseq:NP_001003962.1|refseq:NP_001740.1|refseq:NP_001289561.1|refseq:NP_001289562.1|refseq:XP_005259352.1|refseq:XP_005259353.1	intact:EBI-26610806(see-also)	-	-	figure legend:5a|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2021/01/15	2021/02/24	rogid:ACM0iWdu137zhE8pXo8ckj1opfg9606	rogid:siQugDvaWq0YjOr8qOCf0BsRRKs9606	rigid:uUFXl3YRmAG54LDzQJsV2/JYeLc	false	calmodulin binding peptide plus protein a tag:c-c|mutation:92-92	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q9H173	uniprotkb:P38646	intact:EBI-2840325|uniprotkb:Q8N2L3|uniprotkb:D3DQC2|ensembl:ENSP00000265195|ensembl:ENSP00000378294	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	psi-mi:sil1_human(display_long)|uniprotkb:SIL1(gene name)|psi-mi:SIL1(display_short)|uniprotkb:BiP-associated protein(gene name synonym)|uniprotkb:UNQ545/PRO836(orf name)	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Gatz et al. (2018)	pubmed:31258504|imex:IM-28632	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26686718|imex:IM-28632-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001032722.1|refseq:NP_071909.1|ensembl:ENSG00000120725(gene)|ensembl:ENST00000265195(transcript)|ensembl:ENST00000394817(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9H173|rcsb pdb:6LBN|rcsb pdb:6LEY	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N	intact:EBI-26610806(see-also)	-	-	figure legend:5a|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2021/01/15	2021/02/24	rogid:ACM0iWdu137zhE8pXo8ckj1opfg9606	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	rigid:uUFXl3YRmAG54LDzQJsV2/JYeLc	false	calmodulin binding peptide plus protein a tag:c-c|mutation:92-92	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q9H173	uniprotkb:P11021	intact:EBI-2840325|uniprotkb:Q8N2L3|uniprotkb:D3DQC2|ensembl:ENSP00000265195|ensembl:ENSP00000378294	intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61	psi-mi:sil1_human(display_long)|uniprotkb:SIL1(gene name)|psi-mi:SIL1(display_short)|uniprotkb:BiP-associated protein(gene name synonym)|uniprotkb:UNQ545/PRO836(orf name)	psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Gatz et al. (2018)	pubmed:31258504|imex:IM-28632	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26686718|imex:IM-28632-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001032722.1|refseq:NP_071909.1|ensembl:ENSG00000120725(gene)|ensembl:ENST00000265195(transcript)|ensembl:ENST00000394817(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9H173|rcsb pdb:6LBN|rcsb pdb:6LEY	ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N	intact:EBI-26610806(see-also)	-	-	figure legend:5a|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2021/01/15	2021/02/24	rogid:ACM0iWdu137zhE8pXo8ckj1opfg9606	rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606	rigid:uUFXl3YRmAG54LDzQJsV2/JYeLc	false	calmodulin binding peptide plus protein a tag:c-c|mutation:92-92	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q9H173	uniprotkb:Q8NBT0	intact:EBI-2840325|uniprotkb:Q8N2L3|uniprotkb:D3DQC2|ensembl:ENSP00000265195|ensembl:ENSP00000378294	intact:EBI-2557132|uniprotkb:A4FUW4|uniprotkb:E9PFC6|uniprotkb:Q96IK6|uniprotkb:Q2TAK6|uniprotkb:Q0VDF8|uniprotkb:Q9UFJ8|ensembl:ENSP00000296484	psi-mi:sil1_human(display_long)|uniprotkb:SIL1(gene name)|psi-mi:SIL1(display_short)|uniprotkb:BiP-associated protein(gene name synonym)|uniprotkb:UNQ545/PRO836(orf name)	psi-mi:poc1a_human(display_long)|uniprotkb:WDR51A(gene name synonym)|uniprotkb:WD repeat-containing protein 51A(gene name synonym)|uniprotkb:POC1A(gene name)|psi-mi:POC1A(display_short)|uniprotkb:Pix2(gene name synonym)|uniprotkb:Proteome of centriole protein 1A(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Gatz et al. (2018)	pubmed:31258504|imex:IM-28632	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26686730|imex:IM-28632-16	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001032722.1|refseq:NP_071909.1|ensembl:ENSG00000120725(gene)|ensembl:ENST00000265195(transcript)|ensembl:ENST00000394817(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9H173|rcsb pdb:6LBN|rcsb pdb:6LEY	ensembl:ENSG00000164087(gene)|ensembl:ENST00000296484(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0030030"(cell projection organization)|go:"GO:0036064"(ciliary basal body)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|refseq:NP_001155052.1|refseq:NP_001155053.1|refseq:NP_056241.3	intact:EBI-26610806(see-also)	-	-	figure legend:5a|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2021/01/15	2021/02/24	rogid:ACM0iWdu137zhE8pXo8ckj1opfg9606	rogid:McHLLJ/7U4ZfJoqMeCmDrxuGOpU9606	rigid:uUFXl3YRmAG54LDzQJsV2/JYeLc	false	calmodulin binding peptide plus protein a tag:c-c|mutation:132-132	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q9H173	uniprotkb:P04632	intact:EBI-2840325|uniprotkb:Q8N2L3|uniprotkb:D3DQC2|ensembl:ENSP00000265195|ensembl:ENSP00000378294	intact:EBI-711828|uniprotkb:Q8WTX3|uniprotkb:Q96EW0|uniprotkb:A8K0P1|ensembl:ENSP00000246533|ensembl:ENSP00000464849	psi-mi:sil1_human(display_long)|uniprotkb:SIL1(gene name)|psi-mi:SIL1(display_short)|uniprotkb:BiP-associated protein(gene name synonym)|uniprotkb:UNQ545/PRO836(orf name)	psi-mi:cpns1_human(display_long)|uniprotkb:Calcium-dependent protease small subunit 1(gene name synonym)|uniprotkb:Calcium-dependent protease small subunit(gene name synonym)|uniprotkb:Calpain regulatory subunit(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase small subunit(gene name synonym)|uniprotkb:CAPNS1(gene name)|psi-mi:CAPNS1(display_short)|uniprotkb:CAPN4(gene name synonym)|uniprotkb:CAPNS(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Gatz et al. (2018)	pubmed:31258504|imex:IM-28632	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26686730|imex:IM-28632-16	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001032722.1|refseq:NP_071909.1|ensembl:ENSG00000120725(gene)|ensembl:ENST00000265195(transcript)|ensembl:ENST00000394817(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9H173|rcsb pdb:6LBN|rcsb pdb:6LEY	ensembl:ENSG00000126247(gene)|ensembl:ENST00000246533(transcript)|ensembl:ENST00000588815(transcript)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR029642|mint:P04632|rcsb pdb:1KFU|rcsb pdb:1KFX|rcsb pdb:4PHJ|rcsb pdb:4PHK|rcsb pdb:4PHM|rcsb pdb:4WQ2|rcsb pdb:4WQ3|rcsb pdb:5D69|rcsb pdb:6QLB|reactome:R-HSA-1474228|reactome:R-HSA-6809371|reactome:R-HSA-8862803|refseq:NP_001003962.1|refseq:NP_001740.1|refseq:NP_001289561.1|refseq:NP_001289562.1|refseq:XP_005259352.1|refseq:XP_005259353.1	intact:EBI-26610806(see-also)	-	-	figure legend:5a|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2021/01/15	2021/02/24	rogid:ACM0iWdu137zhE8pXo8ckj1opfg9606	rogid:siQugDvaWq0YjOr8qOCf0BsRRKs9606	rigid:uUFXl3YRmAG54LDzQJsV2/JYeLc	false	calmodulin binding peptide plus protein a tag:c-c|mutation:132-132	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q9H173	uniprotkb:P38646	intact:EBI-2840325|uniprotkb:Q8N2L3|uniprotkb:D3DQC2|ensembl:ENSP00000265195|ensembl:ENSP00000378294	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	psi-mi:sil1_human(display_long)|uniprotkb:SIL1(gene name)|psi-mi:SIL1(display_short)|uniprotkb:BiP-associated protein(gene name synonym)|uniprotkb:UNQ545/PRO836(orf name)	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Gatz et al. (2018)	pubmed:31258504|imex:IM-28632	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26686730|imex:IM-28632-16	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001032722.1|refseq:NP_071909.1|ensembl:ENSG00000120725(gene)|ensembl:ENST00000265195(transcript)|ensembl:ENST00000394817(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9H173|rcsb pdb:6LBN|rcsb pdb:6LEY	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N	intact:EBI-26610806(see-also)	-	-	figure legend:5a|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2021/01/15	2021/02/24	rogid:ACM0iWdu137zhE8pXo8ckj1opfg9606	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	rigid:uUFXl3YRmAG54LDzQJsV2/JYeLc	false	calmodulin binding peptide plus protein a tag:c-c|mutation:132-132	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q9H173	uniprotkb:P11021	intact:EBI-2840325|uniprotkb:Q8N2L3|uniprotkb:D3DQC2|ensembl:ENSP00000265195|ensembl:ENSP00000378294	intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61	psi-mi:sil1_human(display_long)|uniprotkb:SIL1(gene name)|psi-mi:SIL1(display_short)|uniprotkb:BiP-associated protein(gene name synonym)|uniprotkb:UNQ545/PRO836(orf name)	psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Gatz et al. (2018)	pubmed:31258504|imex:IM-28632	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26686730|imex:IM-28632-16	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001032722.1|refseq:NP_071909.1|ensembl:ENSG00000120725(gene)|ensembl:ENST00000265195(transcript)|ensembl:ENST00000394817(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9H173|rcsb pdb:6LBN|rcsb pdb:6LEY	ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N	intact:EBI-26610806(see-also)	-	-	figure legend:5a|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2021/01/15	2021/02/24	rogid:ACM0iWdu137zhE8pXo8ckj1opfg9606	rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606	rigid:uUFXl3YRmAG54LDzQJsV2/JYeLc	false	calmodulin binding peptide plus protein a tag:c-c|mutation:132-132	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q9H173	uniprotkb:P04632	intact:EBI-2840325|uniprotkb:Q8N2L3|uniprotkb:D3DQC2|ensembl:ENSP00000265195|ensembl:ENSP00000378294	intact:EBI-711828|uniprotkb:Q8WTX3|uniprotkb:Q96EW0|uniprotkb:A8K0P1|ensembl:ENSP00000246533|ensembl:ENSP00000464849	psi-mi:sil1_human(display_long)|uniprotkb:SIL1(gene name)|psi-mi:SIL1(display_short)|uniprotkb:BiP-associated protein(gene name synonym)|uniprotkb:UNQ545/PRO836(orf name)	psi-mi:cpns1_human(display_long)|uniprotkb:Calcium-dependent protease small subunit 1(gene name synonym)|uniprotkb:Calcium-dependent protease small subunit(gene name synonym)|uniprotkb:Calpain regulatory subunit(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase small subunit(gene name synonym)|uniprotkb:CAPNS1(gene name)|psi-mi:CAPNS1(display_short)|uniprotkb:CAPN4(gene name synonym)|uniprotkb:CAPNS(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Gatz et al. (2018)	pubmed:31258504|imex:IM-28632	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26686742|imex:IM-28632-18	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001032722.1|refseq:NP_071909.1|ensembl:ENSG00000120725(gene)|ensembl:ENST00000265195(transcript)|ensembl:ENST00000394817(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9H173|rcsb pdb:6LBN|rcsb pdb:6LEY	ensembl:ENSG00000126247(gene)|ensembl:ENST00000246533(transcript)|ensembl:ENST00000588815(transcript)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR029642|mint:P04632|rcsb pdb:1KFU|rcsb pdb:1KFX|rcsb pdb:4PHJ|rcsb pdb:4PHK|rcsb pdb:4PHM|rcsb pdb:4WQ2|rcsb pdb:4WQ3|rcsb pdb:5D69|rcsb pdb:6QLB|reactome:R-HSA-1474228|reactome:R-HSA-6809371|reactome:R-HSA-8862803|refseq:NP_001003962.1|refseq:NP_001740.1|refseq:NP_001289561.1|refseq:NP_001289562.1|refseq:XP_005259352.1|refseq:XP_005259353.1	intact:EBI-26610806(see-also)	-	-	figure legend:5a|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2021/01/15	2021/02/24	rogid:ACM0iWdu137zhE8pXo8ckj1opfg9606	rogid:siQugDvaWq0YjOr8qOCf0BsRRKs9606	rigid:UaZbi1i9H79mVyTMYioi7aiGM8I	false	calmodulin binding peptide plus protein a tag:c-c|mutation:231-232	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q9H173	uniprotkb:P38646	intact:EBI-2840325|uniprotkb:Q8N2L3|uniprotkb:D3DQC2|ensembl:ENSP00000265195|ensembl:ENSP00000378294	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	psi-mi:sil1_human(display_long)|uniprotkb:SIL1(gene name)|psi-mi:SIL1(display_short)|uniprotkb:BiP-associated protein(gene name synonym)|uniprotkb:UNQ545/PRO836(orf name)	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Gatz et al. (2018)	pubmed:31258504|imex:IM-28632	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26686742|imex:IM-28632-18	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001032722.1|refseq:NP_071909.1|ensembl:ENSG00000120725(gene)|ensembl:ENST00000265195(transcript)|ensembl:ENST00000394817(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9H173|rcsb pdb:6LBN|rcsb pdb:6LEY	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N	intact:EBI-26610806(see-also)	-	-	figure legend:5a|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2021/01/15	2021/02/24	rogid:ACM0iWdu137zhE8pXo8ckj1opfg9606	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	rigid:UaZbi1i9H79mVyTMYioi7aiGM8I	false	calmodulin binding peptide plus protein a tag:c-c|mutation:231-232	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q9H173	uniprotkb:P11021	intact:EBI-2840325|uniprotkb:Q8N2L3|uniprotkb:D3DQC2|ensembl:ENSP00000265195|ensembl:ENSP00000378294	intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61	psi-mi:sil1_human(display_long)|uniprotkb:SIL1(gene name)|psi-mi:SIL1(display_short)|uniprotkb:BiP-associated protein(gene name synonym)|uniprotkb:UNQ545/PRO836(orf name)	psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Gatz et al. (2018)	pubmed:31258504|imex:IM-28632	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26686742|imex:IM-28632-18	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001032722.1|refseq:NP_071909.1|ensembl:ENSG00000120725(gene)|ensembl:ENST00000265195(transcript)|ensembl:ENST00000394817(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9H173|rcsb pdb:6LBN|rcsb pdb:6LEY	ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N	intact:EBI-26610806(see-also)	-	-	figure legend:5a|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2021/01/15	2021/02/24	rogid:ACM0iWdu137zhE8pXo8ckj1opfg9606	rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606	rigid:UaZbi1i9H79mVyTMYioi7aiGM8I	false	calmodulin binding peptide plus protein a tag:c-c|mutation:231-232	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q9H173	uniprotkb:Q9UBS4	intact:EBI-2840325|uniprotkb:Q8N2L3|uniprotkb:D3DQC2|ensembl:ENSP00000265195|ensembl:ENSP00000378294	intact:EBI-713113|ensembl:ENSP00000265028|ensembl:ENSP00000414398|uniprotkb:Q542Y5|uniprotkb:Q542Y9|uniprotkb:Q6IAQ8|uniprotkb:Q96JC6	psi-mi:sil1_human(display_long)|uniprotkb:SIL1(gene name)|psi-mi:SIL1(display_short)|uniprotkb:BiP-associated protein(gene name synonym)|uniprotkb:UNQ545/PRO836(orf name)	psi-mi:djb11_human(display_long)|uniprotkb:HDJ9(gene name synonym)|uniprotkb:DnaJ protein homolog 9(gene name synonym)|uniprotkb:ER-associated Hsp40 co-chaperone(gene name synonym)|uniprotkb:ER-associated DNAJ(gene name synonym)|uniprotkb:HEDJ(gene name synonym)|uniprotkb:Human DnaJ protein 9(gene name synonym)|uniprotkb:PWP1-interacting protein 4(gene name synonym)|uniprotkb:APOBEC1-binding protein 2(gene name synonym)|uniprotkb:PSEC0121(orf name)|uniprotkb:DNAJB11(gene name)|psi-mi:DNAJB11(display_short)|uniprotkb:EDJ(gene name synonym)|uniprotkb:ERJ3(gene name synonym)|uniprotkb:UNQ537/PRO1080(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 3(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Gatz et al. (2018)	pubmed:31258504|imex:IM-28632	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26686756|imex:IM-28632-20	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001032722.1|refseq:NP_071909.1|ensembl:ENSG00000120725(gene)|ensembl:ENST00000265195(transcript)|ensembl:ENST00000394817(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9H173|rcsb pdb:6LBN|rcsb pdb:6LEY	ensembl:ENSG00000090520(gene)|ensembl:ENST00000265028(transcript)|ensembl:ENST00000439351(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0101031"(chaperone complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:Q9UBS4|reactome:R-HSA-381038|go:"GO:0006457"(protein folding)|refseq:NP_057390.1|dip:DIP-29678N	intact:EBI-26610806(see-also)	-	-	figure legend:5a|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2021/01/15	2021/02/24	rogid:ACM0iWdu137zhE8pXo8ckj1opfg9606	rogid:B8jV6uvPmoGzOEpe4qrMiYloSok9606	rigid:VGQ/lA/2HTp2Tva05jIp4vlH6aA	false	calmodulin binding peptide plus protein a tag:c-c|mutation:312-312	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q9H173	uniprotkb:P38646	intact:EBI-2840325|uniprotkb:Q8N2L3|uniprotkb:D3DQC2|ensembl:ENSP00000265195|ensembl:ENSP00000378294	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	psi-mi:sil1_human(display_long)|uniprotkb:SIL1(gene name)|psi-mi:SIL1(display_short)|uniprotkb:BiP-associated protein(gene name synonym)|uniprotkb:UNQ545/PRO836(orf name)	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Gatz et al. (2018)	pubmed:31258504|imex:IM-28632	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26686756|imex:IM-28632-20	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001032722.1|refseq:NP_071909.1|ensembl:ENSG00000120725(gene)|ensembl:ENST00000265195(transcript)|ensembl:ENST00000394817(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9H173|rcsb pdb:6LBN|rcsb pdb:6LEY	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N	intact:EBI-26610806(see-also)	-	-	figure legend:5a|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2021/01/15	2021/02/24	rogid:ACM0iWdu137zhE8pXo8ckj1opfg9606	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	rigid:VGQ/lA/2HTp2Tva05jIp4vlH6aA	false	calmodulin binding peptide plus protein a tag:c-c|mutation:312-312	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q9H173	uniprotkb:P11021	intact:EBI-2840325|uniprotkb:Q8N2L3|uniprotkb:D3DQC2|ensembl:ENSP00000265195|ensembl:ENSP00000378294	intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61	psi-mi:sil1_human(display_long)|uniprotkb:SIL1(gene name)|psi-mi:SIL1(display_short)|uniprotkb:BiP-associated protein(gene name synonym)|uniprotkb:UNQ545/PRO836(orf name)	psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Gatz et al. (2018)	pubmed:31258504|imex:IM-28632	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26686756|imex:IM-28632-20	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001032722.1|refseq:NP_071909.1|ensembl:ENSG00000120725(gene)|ensembl:ENST00000265195(transcript)|ensembl:ENST00000394817(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9H173|rcsb pdb:6LBN|rcsb pdb:6LEY	ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N	intact:EBI-26610806(see-also)	-	-	figure legend:5a|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2021/01/15	2021/02/24	rogid:ACM0iWdu137zhE8pXo8ckj1opfg9606	rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606	rigid:VGQ/lA/2HTp2Tva05jIp4vlH6aA	false	calmodulin binding peptide plus protein a tag:c-c|mutation:312-312	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q9H173	uniprotkb:P04632	intact:EBI-2840325|uniprotkb:Q8N2L3|uniprotkb:D3DQC2|ensembl:ENSP00000265195|ensembl:ENSP00000378294	intact:EBI-711828|uniprotkb:Q8WTX3|uniprotkb:Q96EW0|uniprotkb:A8K0P1|ensembl:ENSP00000246533|ensembl:ENSP00000464849	psi-mi:sil1_human(display_long)|uniprotkb:SIL1(gene name)|psi-mi:SIL1(display_short)|uniprotkb:BiP-associated protein(gene name synonym)|uniprotkb:UNQ545/PRO836(orf name)	psi-mi:cpns1_human(display_long)|uniprotkb:Calcium-dependent protease small subunit 1(gene name synonym)|uniprotkb:Calcium-dependent protease small subunit(gene name synonym)|uniprotkb:Calpain regulatory subunit(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase small subunit(gene name synonym)|uniprotkb:CAPNS1(gene name)|psi-mi:CAPNS1(display_short)|uniprotkb:CAPN4(gene name synonym)|uniprotkb:CAPNS(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Gatz et al. (2018)	pubmed:31258504|imex:IM-28632	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26686756|imex:IM-28632-20	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001032722.1|refseq:NP_071909.1|ensembl:ENSG00000120725(gene)|ensembl:ENST00000265195(transcript)|ensembl:ENST00000394817(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9H173|rcsb pdb:6LBN|rcsb pdb:6LEY	ensembl:ENSG00000126247(gene)|ensembl:ENST00000246533(transcript)|ensembl:ENST00000588815(transcript)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR029642|mint:P04632|rcsb pdb:1KFU|rcsb pdb:1KFX|rcsb pdb:4PHJ|rcsb pdb:4PHK|rcsb pdb:4PHM|rcsb pdb:4WQ2|rcsb pdb:4WQ3|rcsb pdb:5D69|rcsb pdb:6QLB|reactome:R-HSA-1474228|reactome:R-HSA-6809371|reactome:R-HSA-8862803|refseq:NP_001003962.1|refseq:NP_001740.1|refseq:NP_001289561.1|refseq:NP_001289562.1|refseq:XP_005259352.1|refseq:XP_005259353.1	intact:EBI-26610806(see-also)	-	-	figure legend:5a|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2021/01/15	2021/02/24	rogid:ACM0iWdu137zhE8pXo8ckj1opfg9606	rogid:siQugDvaWq0YjOr8qOCf0BsRRKs9606	rigid:VGQ/lA/2HTp2Tva05jIp4vlH6aA	false	calmodulin binding peptide plus protein a tag:c-c|mutation:312-312	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q9H173	uniprotkb:Q9UBS4	intact:EBI-2840325|uniprotkb:Q8N2L3|uniprotkb:D3DQC2|ensembl:ENSP00000265195|ensembl:ENSP00000378294	intact:EBI-713113|ensembl:ENSP00000265028|ensembl:ENSP00000414398|uniprotkb:Q542Y5|uniprotkb:Q542Y9|uniprotkb:Q6IAQ8|uniprotkb:Q96JC6	psi-mi:sil1_human(display_long)|uniprotkb:SIL1(gene name)|psi-mi:SIL1(display_short)|uniprotkb:BiP-associated protein(gene name synonym)|uniprotkb:UNQ545/PRO836(orf name)	psi-mi:djb11_human(display_long)|uniprotkb:HDJ9(gene name synonym)|uniprotkb:DnaJ protein homolog 9(gene name synonym)|uniprotkb:ER-associated Hsp40 co-chaperone(gene name synonym)|uniprotkb:ER-associated DNAJ(gene name synonym)|uniprotkb:HEDJ(gene name synonym)|uniprotkb:Human DnaJ protein 9(gene name synonym)|uniprotkb:PWP1-interacting protein 4(gene name synonym)|uniprotkb:APOBEC1-binding protein 2(gene name synonym)|uniprotkb:PSEC0121(orf name)|uniprotkb:DNAJB11(gene name)|psi-mi:DNAJB11(display_short)|uniprotkb:EDJ(gene name synonym)|uniprotkb:ERJ3(gene name synonym)|uniprotkb:UNQ537/PRO1080(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 3(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Gatz et al. (2018)	pubmed:31258504|imex:IM-28632	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26686771|imex:IM-28632-22	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001032722.1|refseq:NP_071909.1|ensembl:ENSG00000120725(gene)|ensembl:ENST00000265195(transcript)|ensembl:ENST00000394817(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9H173|rcsb pdb:6LBN|rcsb pdb:6LEY	ensembl:ENSG00000090520(gene)|ensembl:ENST00000265028(transcript)|ensembl:ENST00000439351(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0101031"(chaperone complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:Q9UBS4|reactome:R-HSA-381038|go:"GO:0006457"(protein folding)|refseq:NP_057390.1|dip:DIP-29678N	intact:EBI-26610806(see-also)	-	-	figure legend:5a|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2021/01/15	2021/02/24	rogid:ACM0iWdu137zhE8pXo8ckj1opfg9606	rogid:B8jV6uvPmoGzOEpe4qrMiYloSok9606	rigid:VGQ/lA/2HTp2Tva05jIp4vlH6aA	false	calmodulin binding peptide plus protein a tag:c-c|mutation:457-457	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q9H173	uniprotkb:P38646	intact:EBI-2840325|uniprotkb:Q8N2L3|uniprotkb:D3DQC2|ensembl:ENSP00000265195|ensembl:ENSP00000378294	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	psi-mi:sil1_human(display_long)|uniprotkb:SIL1(gene name)|psi-mi:SIL1(display_short)|uniprotkb:BiP-associated protein(gene name synonym)|uniprotkb:UNQ545/PRO836(orf name)	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Gatz et al. (2018)	pubmed:31258504|imex:IM-28632	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26686771|imex:IM-28632-22	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001032722.1|refseq:NP_071909.1|ensembl:ENSG00000120725(gene)|ensembl:ENST00000265195(transcript)|ensembl:ENST00000394817(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9H173|rcsb pdb:6LBN|rcsb pdb:6LEY	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N	intact:EBI-26610806(see-also)	-	-	figure legend:5a|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2021/01/15	2021/02/24	rogid:ACM0iWdu137zhE8pXo8ckj1opfg9606	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	rigid:VGQ/lA/2HTp2Tva05jIp4vlH6aA	false	calmodulin binding peptide plus protein a tag:c-c|mutation:457-457	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q9H173	uniprotkb:P11021	intact:EBI-2840325|uniprotkb:Q8N2L3|uniprotkb:D3DQC2|ensembl:ENSP00000265195|ensembl:ENSP00000378294	intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61	psi-mi:sil1_human(display_long)|uniprotkb:SIL1(gene name)|psi-mi:SIL1(display_short)|uniprotkb:BiP-associated protein(gene name synonym)|uniprotkb:UNQ545/PRO836(orf name)	psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Gatz et al. (2018)	pubmed:31258504|imex:IM-28632	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26686771|imex:IM-28632-22	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001032722.1|refseq:NP_071909.1|ensembl:ENSG00000120725(gene)|ensembl:ENST00000265195(transcript)|ensembl:ENST00000394817(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9H173|rcsb pdb:6LBN|rcsb pdb:6LEY	ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N	intact:EBI-26610806(see-also)	-	-	figure legend:5a|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2021/01/15	2021/02/24	rogid:ACM0iWdu137zhE8pXo8ckj1opfg9606	rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606	rigid:VGQ/lA/2HTp2Tva05jIp4vlH6aA	false	calmodulin binding peptide plus protein a tag:c-c|mutation:457-457	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:Q9H173	uniprotkb:P04632	intact:EBI-2840325|uniprotkb:Q8N2L3|uniprotkb:D3DQC2|ensembl:ENSP00000265195|ensembl:ENSP00000378294	intact:EBI-711828|uniprotkb:Q8WTX3|uniprotkb:Q96EW0|uniprotkb:A8K0P1|ensembl:ENSP00000246533|ensembl:ENSP00000464849	psi-mi:sil1_human(display_long)|uniprotkb:SIL1(gene name)|psi-mi:SIL1(display_short)|uniprotkb:BiP-associated protein(gene name synonym)|uniprotkb:UNQ545/PRO836(orf name)	psi-mi:cpns1_human(display_long)|uniprotkb:Calcium-dependent protease small subunit 1(gene name synonym)|uniprotkb:Calcium-dependent protease small subunit(gene name synonym)|uniprotkb:Calpain regulatory subunit(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase small subunit(gene name synonym)|uniprotkb:CAPNS1(gene name)|psi-mi:CAPNS1(display_short)|uniprotkb:CAPN4(gene name synonym)|uniprotkb:CAPNS(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Gatz et al. (2018)	pubmed:31258504|imex:IM-28632	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26686771|imex:IM-28632-22	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001032722.1|refseq:NP_071909.1|ensembl:ENSG00000120725(gene)|ensembl:ENST00000265195(transcript)|ensembl:ENST00000394817(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9H173|rcsb pdb:6LBN|rcsb pdb:6LEY	ensembl:ENSG00000126247(gene)|ensembl:ENST00000246533(transcript)|ensembl:ENST00000588815(transcript)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR029642|mint:P04632|rcsb pdb:1KFU|rcsb pdb:1KFX|rcsb pdb:4PHJ|rcsb pdb:4PHK|rcsb pdb:4PHM|rcsb pdb:4WQ2|rcsb pdb:4WQ3|rcsb pdb:5D69|rcsb pdb:6QLB|reactome:R-HSA-1474228|reactome:R-HSA-6809371|reactome:R-HSA-8862803|refseq:NP_001003962.1|refseq:NP_001740.1|refseq:NP_001289561.1|refseq:NP_001289562.1|refseq:XP_005259352.1|refseq:XP_005259353.1	intact:EBI-26610806(see-also)	-	-	figure legend:5a|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2021/01/15	2021/02/24	rogid:ACM0iWdu137zhE8pXo8ckj1opfg9606	rogid:siQugDvaWq0YjOr8qOCf0BsRRKs9606	rigid:VGQ/lA/2HTp2Tva05jIp4vlH6aA	false	calmodulin binding peptide plus protein a tag:c-c|mutation:457-457	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)