#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9NRI5	uniprotkb:Q9UIV1	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2105113|uniprotkb:A8MZM5|uniprotkb:Q7Z530|uniprotkb:D3DSP6|uniprotkb:B3KMP1|uniprotkb:B3KN35|uniprotkb:G3V108|ensembl:ENSP00000355279	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:cnot7_human(display_long)|uniprotkb:CNOT7(gene name)|psi-mi:CNOT7(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:BTG1-binding factor 1(gene name synonym)|uniprotkb:Caf1a(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001309026.1|refseq:NP_001309028.1|refseq:NP_001309029.1|refseq:NP_001309016.1|refseq:NP_001309017.1|refseq:NP_001309018.1|refseq:NP_001309019.1|refseq:NP_001309020.1|refseq:NP_001309021.1|refseq:NP_001309022.1|refseq:NP_001309023.1|refseq:NP_001309024.1|refseq:NP_001309025.1|refseq:NP_037486.2|refseq:NP_473367.2|refseq:XP_005273538.1|refseq:NP_001309027.1|dip:DIP-41902N|ensembl:ENSG00000198791(gene)|ensembl:ENST00000361272(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0042509"(regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039636|interpro:IPR039637|mint:Q9UIV1|rcsb pdb:2D5R|rcsb pdb:4GMJ|rcsb pdb:7AX1|reactome:R-HSA-429947|reactome:R-HSA-6804115	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:+bu5LFmE8SFVSqNkFf91SSN3kVI9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9BUQ8	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-540096|uniprotkb:B2R600|uniprotkb:O43188|uniprotkb:B4DH15|intact:EBI-2557638|ensembl:ENSP00000310723	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:ddx23_human(display_long)|uniprotkb:DEAD box protein 23(gene name synonym)|uniprotkb:100 kDa U5 snRNP-specific protein(gene name synonym)|uniprotkb:U5-100kD(gene name synonym)|uniprotkb:PRP28 homolog(gene name synonym)|uniprotkb:DDX23(gene name)|psi-mi:DDX23(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_004809.2|ensembl:ENSG00000174243(gene)|ensembl:ENST00000308025(transcript)|go:"GO:0000354"(cis assembly of pre-catalytic spliceosome)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0008380"(RNA splicing)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0062176"(R-loop disassembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q9BUQ8|rcsb pdb:3JCR|rcsb pdb:4NHO|rcsb pdb:6AH0|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163|reactome:R-HSA-72165|dip:DIP-34974N	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:tEDp48akFaCjRBBXB4jtyrAsLQ89606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q8WXF1	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1392258|uniprotkb:Q5JTQ3|uniprotkb:Q8NCZ9|uniprotkb:Q8WXE8|uniprotkb:Q9NV36|ensembl:ENSP00000343966|ensembl:ENSP00000481916	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:pspc1_human(display_long)|uniprotkb:PSPC1(gene name)|psi-mi:PSPC1(display_short)|uniprotkb:PSP1(gene name synonym)|uniprotkb:Paraspeckle protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:XP_006719907.1|refseq:NP_001035879.1|dip:DIP-39028N|refseq:XP_016876139.1|ensembl:ENSG00000121390(gene)|ensembl:ENST00000338910(transcript)|ensembl:ENST00000619300(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034522|interpro:IPR034523|interpro:IPR035979|mint:Q8WXF1|rcsb pdb:3SDE|rcsb pdb:5IFN|rcsb pdb:5WPA	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:voQ5zJMl7FYato9iDkUYfzZ3q/k9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q05048	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1789619|uniprotkb:Q5QPD8|ensembl:ENSP00000217109	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:cstf1_human(display_long)|uniprotkb:CSTF1(gene name)|psi-mi:CSTF1(display_short)|uniprotkb:CF-1 50 kDa subunit(gene name synonym)|uniprotkb:Cleavage stimulation factor 50 kDa subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:XP_011526902.1|refseq:NP_001028693.1|refseq:NP_001028694.1|refseq:NP_001315.1|ensembl:ENSG00000101138(gene)|ensembl:ENST00000217109(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005848"(mRNA cleavage stimulating factor complex)|go:"GO:0031124"(mRNA 3'-end processing)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR032028|interpro:IPR036322|interpro:IPR038184|interpro:IPR044633|mint:Q05048|rcsb pdb:6B3X|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:p1WA38/ygDg6E9lsofH6JH8wU7k9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P61009	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-6166040|ensembl:ENSP00000427463|uniprotkb:P12280|uniprotkb:Q9H0S7	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:spcs3_human(display_long)|uniprotkb:SPCS3(gene name)|psi-mi:SPCS3(display_short)|uniprotkb:Microsomal signal peptidase 22/23 kDa subunit(gene name synonym)|uniprotkb:SPC22(gene name synonym)|uniprotkb:UNQ1841/PRO3567(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSG00000129128(gene)|ensembl:ENST00000503362(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006465"(signal peptide processing)|go:"GO:0006508"(proteolysis)|go:"GO:0008233"(peptidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR007653(Signal peptidase 22 kDa subunit)|mint:P61009|reactome:R-HSA-1799339|reactome:R-HSA-381771|reactome:R-HSA-400511|reactome:R-HSA-422085|refseq:NP_068747.1	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:IJjfzKRjeZefoy2znnC4XC6wgOU9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P53674	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-7519424|intact:MINT-8162887|intact:MINT-5161833|ensembl:ENSP00000497249	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:crbb1_human(display_long)|uniprotkb:CRYBB1(gene name)|psi-mi:CRYBB1(display_short)|uniprotkb:Beta-B1 crystallin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:XP_011528201.1|refseq:NP_001878.1|ensembl:ENSG00000100122(gene)|ensembl:ENST00000647684(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0007601"(visual perception)|interpro:IPR001064(Beta and gamma crystallin)|interpro:IPR011024(Gamma-crystallin related)|interpro:IPR033059|mint:P53674|rcsb pdb:1OKI	-	-	function:"Defects in CRYBB1 are the cause of autosomal recessive congenital nuclear cataract type 3 (CATCN3) [MIM:611544]. CATCN3 is a form of non-syndromic congenital cataract. Non-syndromic congenital cataracts vary markedly in severity and morphology, affecting the nuclear, cortical, polar, or subcapsular parts of the lens or, in severe cases, the entire lens, with a variety of types of opacity. They are one of the major causes of vision loss in children worldwide and are responsible for approximately one third of blindness in infants. Congenital cataracts can lead to permanent blindness by interfering with the sharp focus of light on the retina during critical developmental intervals"|comment:mint|function:Crystallins are the dominant structural components of the vertebrate eye lens	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:eJNGIH/zBV3wjYXqbKB5ftU9CVY9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P35556	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-6164392|ensembl:ENSP00000424571|ensembl:ENSP00000262464|uniprotkb:B4DU01|uniprotkb:Q59ES6	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:fbn2_human(display_long)|uniprotkb:FBN2(gene name)|psi-mi:FBN2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	interpro:IPR026823|interpro:IPR036773|interpro:IPR040872|mint:P35556|reactome:R-HSA-1474228|reactome:R-HSA-1566948|reactome:R-HSA-2129379|interpro:IPR018097|ensembl:ENSG00000138829(gene)|ensembl:ENST00000262464(transcript)|ensembl:ENST00000508053(transcript)|go:"GO:0001527"(microfibril)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0030023"(extracellular matrix constituent conferring elasticity)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035583"(sequestering of TGFbeta in extracellular matrix)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0048048"(embryonic eye morphogenesis)|go:"GO:0060346"(bone trabecula formation)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011398(Fibrillin)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR017878|refseq:NP_001990.2	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:iqBnjHuy9kU3serIc5tPWGIDzUc9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:O14578	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-8623109|ensembl:ENSP00000261833|uniprotkb:Q6XUH8|intact:MINT-2795177|uniprotkb:Q2M5E1|uniprotkb:Q9UPZ7|uniprotkb:Q86UQ9	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:ctro_human(display_long)|uniprotkb:CIT(gene name)|psi-mi:CIT(display_short)|uniprotkb:KIAA0949(gene name synonym)|uniprotkb:STK21(gene name synonym)|uniprotkb:CRIK(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 21(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSG00000122966(gene)|ensembl:ENST00000261833(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017405(Citron Rho-interacting kinase)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR037708|mint:O14578|reactome:R-HSA-5625900|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013149|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0005737"(cytoplasm)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0048699"(generation of neurons)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|refseq:NP_001193928.1|refseq:NP_009105.1	-	-	function:Required for KIF14 localization to the central spindle and midbody. May play a role in cytokinesis. Putative RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1. It probably binds p21 with a tighter specificity in vivo. Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Plays an important role in the regulation of cytokinesis and the development of the central nervous system|comment:mint	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:yA7y17lwftFoF2/BfbtC3aanJaI9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9Y2J2	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-310986|uniprotkb:O95713|uniprotkb:Q9BRP5|ensembl:ENSP00000343158|uniprotkb:B7Z4I5|uniprotkb:F5GX05	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:e41l3_human(display_long)|uniprotkb:EPB41L3(gene name)|psi-mi:EPB41L3(display_short)|uniprotkb:DAL1(gene name synonym)|uniprotkb:KIAA0987(gene name synonym)|uniprotkb:4.1B(gene name synonym)|uniprotkb:Differentially expressed in adenocarcinoma of the lung protein 1(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 4.1-like 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_036439.2|refseq:NP_001268462.1|refseq:NP_001268463.1|refseq:NP_001268464.1|ensembl:ENSG00000082397(gene)|ensembl:ENST00000341928(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0002175"(protein localization to paranode region of axon)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030054"(cell junction)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030913"(paranodal junction assembly)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0033270"(paranode region of axon)|go:"GO:0043217"(myelin maintenance)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0071205"(protein localization to juxtaparanode region of axon)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0106006"(cytoskeletal protein-membrane anchor activity)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR007477(SAB)|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030691|interpro:IPR035963|mint:Q9Y2J2|rcsb pdb:2HE7|rcsb pdb:3BIN|rcsb pdb:5RYM|rcsb pdb:5RYN|rcsb pdb:5RYO|rcsb pdb:5RYP|rcsb pdb:5RYQ|rcsb pdb:5RYR|rcsb pdb:5RYS|rcsb pdb:5RYT|rcsb pdb:5RYU|rcsb pdb:5RYV|rcsb pdb:5RYW|rcsb pdb:5RYX|rcsb pdb:5RYY|rcsb pdb:5RYZ|rcsb pdb:5RZ0|rcsb pdb:5RZ1|rcsb pdb:5RZ2|rcsb pdb:5RZ3|rcsb pdb:5RZ4|rcsb pdb:5RZ5|rcsb pdb:5RZ6|rcsb pdb:5RZ7|rcsb pdb:5RZ8|rcsb pdb:5RZ9|rcsb pdb:5RZA|rcsb pdb:5RZB|rcsb pdb:5RZC|rcsb pdb:5RZD|rcsb pdb:5RZE|rcsb pdb:5RZF|rcsb pdb:5RZG|rcsb pdb:5RZH|rcsb pdb:5RZI|rcsb pdb:5RZJ|rcsb pdb:5RZK|rcsb pdb:5RZL|rcsb pdb:5RZM|rcsb pdb:5RZN|rcsb pdb:5RZO|rcsb pdb:5RZP|rcsb pdb:5RZQ|rcsb pdb:5RZR|rcsb pdb:5RZS|rcsb pdb:5RZT|rcsb pdb:5RZU|rcsb pdb:5RZV|rcsb pdb:5RZW|rcsb pdb:5RZX|rcsb pdb:5RZY|rcsb pdb:5RZZ|rcsb pdb:5S00|rcsb pdb:6IBE|reactome:R-HSA-6794361|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:XP_016881125.1|dip:DIP-17035N	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:Uwq5dqLRdgFLPBhXZROSRJstl709606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9UQ13	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-993879|uniprotkb:O76063|uniprotkb:A8K9W8|uniprotkb:B3KR23|uniprotkb:Q5VZS8|uniprotkb:Q5VZS9|ensembl:ENSP00000358464	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:shoc2_human(display_long)|uniprotkb:Protein soc-2 homolog(gene name synonym)|uniprotkb:SHOC2(gene name)|psi-mi:SHOC2(display_short)|uniprotkb:KIAA0862(gene name synonym)|uniprotkb:Protein sur-8 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_031399.2|refseq:NP_001311265.1|refseq:NP_001311266.1|refseq:NP_001255968.1|refseq:XP_016872191.1|refseq:XP_016872192.1|refseq:XP_016872193.1|ensembl:ENSG00000108061(gene)|ensembl:ENST00000369452(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR027036|interpro:IPR032675|mint:Q9UQ13|reactome:R-HSA-5673000|reactome:R-HSA-9660537	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:0RkCETF3NG59IZjnJevXVYkzBJU9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9UPN7	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-359745|uniprotkb:Q2M2H3|uniprotkb:Q504V2|uniprotkb:Q6NVJ6|uniprotkb:Q9BU97|intact:EBI-28973105|ensembl:ENSP00000414202|ensembl:ENSP00000467521	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:pp6r1_human(display_long)|uniprotkb:PPP6R1(gene name)|psi-mi:PPP6R1(display_short)|uniprotkb:KIAA1115(gene name synonym)|uniprotkb:PP6R1(gene name synonym)|uniprotkb:SAPS domain family member 1(gene name synonym)|uniprotkb:SAPS1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_055746.3|ensembl:ENSP00000414202|ensembl:ENSP00000467521|ensembl:ENSG00000105063(gene)|ensembl:ENST00000412770(transcript)|ensembl:ENST00000587283(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007587(SIT4 phosphatase-associated protein)|interpro:IPR016024(Armadillo-type fold)|mint:Q9UPN7|reactome:R-HSA-204005|dip:DIP-27589N	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:Nab2lMgz1rQizyvjdbMrJUMNB+I9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9UIJ7	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-3916527|uniprotkb:Q5VYW6|uniprotkb:Q9NPB4|uniprotkb:Q9H576|uniprotkb:D3DRI1|uniprotkb:Q9HC01|uniprotkb:B4DP58|uniprotkb:E7ET30|ensembl:ENSP00000371230	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:kad3_human(display_long)|uniprotkb:AK3(gene name)|psi-mi:AK3(display_short)|uniprotkb:AK3L1(gene name synonym)|uniprotkb:AK6(gene name synonym)|uniprotkb:AKL3L(gene name synonym)|uniprotkb:Adenylate kinase 3(gene name synonym)|uniprotkb:Adenylate kinase 3 alpha-like 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001186781.1|refseq:NP_001186782.1|refseq:NP_001186784.1|refseq:NP_001186785.1|refseq:NP_057366.2|ensembl:ENSG00000147853(gene)|ensembl:ENST00000381809(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006172"(ADP biosynthetic process)|go:"GO:0007596"(blood coagulation)|go:"GO:0009142"(nucleoside triphosphate biosynthetic process)|go:"GO:0046033"(AMP metabolic process)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046041"(ITP metabolic process)|go:"GO:0046051"(UTP metabolic process)|go:"GO:0046899"(nucleoside triphosphate adenylate kinase activity)|go:"GO:0046940"(nucleoside monophosphate phosphorylation)|interpro:IPR000850(Adenylate kinase)|interpro:IPR006259(Adenylate kinase, subfamily)|interpro:IPR007862(Adenylate kinase, zinc-finger lid region)|interpro:IPR028586|interpro:IPR033690|interpro:IPR036193|mint:Q9UIJ7|rcsb pdb:1ZD8|rcsb pdb:6ZJB|rcsb pdb:6ZJD|rcsb pdb:6ZJE|reactome:R-HSA-983231|interpro:IPR027417	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:NDt9xiBjW8L9uXYnyZhVYpVybfA9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9UHB9	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1048560|uniprotkb:Q8NCJ4|uniprotkb:Q8WUK2|uniprotkb:B3KUU5|uniprotkb:B3KWY7|uniprotkb:G3V1U4|ensembl:ENSP00000312066	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:srp68_human(display_long)|uniprotkb:SRP68(gene name)|psi-mi:SRP68(display_short)|uniprotkb:Signal recognition particle 68 kDa protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001247431.1|refseq:NP_001247432.1|refseq:NP_055045.2|interpro:IPR026258|interpro:IPR034652|interpro:IPR038253|mint:Q9UHB9|rcsb pdb:4P3E|rcsb pdb:4P3F|rcsb pdb:5M72|rcsb pdb:5M73|rcsb pdb:5WRV|rcsb pdb:7NFX|reactome:R-HSA-1799339|ensembl:ENSG00000167881(gene)|ensembl:ENST00000307877(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030942"(endoplasmic reticulum signal peptide binding)|go:"GO:0042493"|go:"GO:0048500"(signal recognition particle)|dip:DIP-50905N	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:8WwEMUV+QzJGJ6G7xufvSibYTSY9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9UH99	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1044964|uniprotkb:O75156|uniprotkb:Q2NKN8|uniprotkb:Q6B4H1|uniprotkb:Q7Z3E3|uniprotkb:Q2T9F7|ensembl:ENSP00000383992|ensembl:ENSP00000385740|uniprotkb:B0QY62|uniprotkb:Q504T5	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:sun2_human(display_long)|uniprotkb:Sad1/unc-84 protein-like 2(gene name synonym)|uniprotkb:Rab5-interacting protein(gene name synonym)|uniprotkb:SUN2(gene name)|psi-mi:SUN2(display_short)|uniprotkb:FRIGG(gene name synonym)|uniprotkb:KIAA0668(gene name synonym)|uniprotkb:RAB5IP(gene name synonym)|uniprotkb:UNC84B(gene name synonym)|uniprotkb:Protein unc-84 homolog B(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001186508.1|refseq:NP_001186509.1|refseq:NP_056189.1|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005521"(lamin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0008017"(microtubule binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0021817"(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031022"(nuclear migration along microfilament)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051642"(centrosome localization)|go:"GO:0090292"(nuclear matrix anchoring at nuclear membrane)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|go:"GO:0000781"(chromosome, telomeric region)|interpro:IPR012919(Sad1/UNC-like, C-terminal)|interpro:IPR030272|interpro:IPR040994|mint:Q9UH99|ensembl:ENSG00000100242(gene)|ensembl:ENST00000405510(transcript)|ensembl:ENST00000406622(transcript)|rcsb pdb:4DXS|rcsb pdb:4DXT|rcsb pdb:4FI9|rcsb pdb:6WMD|rcsb pdb:6WME|rcsb pdb:6WMF|rcsb pdb:6WMG|reactome:R-HSA-1221632|rcsb pdb:4DXR|rcsb pdb:3UNP	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:nG0s5eHv6AGh8rcdhTIJ1RdpfbU9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9UGM3	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1044970|uniprotkb:Q59EX0|uniprotkb:Q5JR26|uniprotkb:Q6MZN4|uniprotkb:Q96DU4|uniprotkb:Q9UGM2|uniprotkb:Q9UJ57|uniprotkb:Q9UKJ4|uniprotkb:Q9Y211|uniprotkb:Q9Y4V9|uniprotkb:A6NDG4|uniprotkb:A6NDJ5|uniprotkb:A8E4R5|uniprotkb:B1ARE7|uniprotkb:B1ARE8|uniprotkb:B1ARE9|uniprotkb:B1ARF0|uniprotkb:B7Z8Y2|uniprotkb:F8WEF7|ensembl:ENSP00000357905|ensembl:ENSP00000484603|ensembl:ENSP00000498825	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:dmbt1_human(display_long)|uniprotkb:Glycoprotein 340(gene name synonym)|uniprotkb:Surfactant pulmonary-associated D-binding protein(gene name synonym)|uniprotkb:Hensin(gene name synonym)|uniprotkb:DMBT1(gene name)|psi-mi:DMBT1(display_short)|uniprotkb:GP340(gene name synonym)|uniprotkb:Salivary agglutinin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_004397.2|refseq:NP_015568.2|refseq:NP_060049.2|refseq:XP_011537690.1|refseq:XP_011537693.1|refseq:XP_011537707.1|refseq:NP_001307573.1|dip:DIP-50763N|ensembl:ENSG00000187908(gene)|ensembl:ENST00000368909(transcript)|ensembl:ENST00000619379(transcript)|ensembl:ENST00000652446(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006952"(defense response)|go:"GO:0015031"(protein transport)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035375"(zymogen binding)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042494"(detection of bacterial lipoprotein)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0043152"(induction of bacterial agglutination)|go:"GO:0045087"(innate immune response)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070891"(lipoteichoic acid binding)|go:"GO:1904399"(heparan sulfate binding)|interpro:IPR000859(CUB)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR001507(Endoglin/CD105 antigen)|interpro:IPR017448(Speract/scavenger receptor related)|interpro:IPR017977|interpro:IPR035914|interpro:IPR036772|interpro:IPR042235|mint:Q9UGM3|rcsb pdb:6SA4|rcsb pdb:6SA5|rcsb pdb:6SAN|reactome:R-HSA-5683826	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:A0Aw2F/rHW8mFmPDg4xOTy8NGzg9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9UDY2	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1042602|uniprotkb:Q15883|uniprotkb:Q5VXL0|uniprotkb:Q8N756|uniprotkb:Q8NI14|uniprotkb:Q99839|uniprotkb:Q9UDY0|uniprotkb:Q9UDY1|uniprotkb:A2A3H9|uniprotkb:Q5VXL1|intact:EBI-10989219|ensembl:ENSP00000366453|uniprotkb:B7Z2R8|uniprotkb:B7Z7T6|uniprotkb:F5H301|uniprotkb:F5H886	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:zo2_human(display_long)|uniprotkb:TJP2(gene name)|psi-mi:TJP2(display_short)|uniprotkb:X104(gene name synonym)|uniprotkb:Zonula occludens protein 2(gene name synonym)|uniprotkb:Zona occludens protein 2(gene name synonym)|uniprotkb:Tight junction protein 2(gene name synonym)|uniprotkb:ZO2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001163886.1|refseq:NP_001163887.1|refseq:NP_004808.2|refseq:XP_011517508.1|refseq:XP_011517509.1|refseq:XP_011517510.1|refseq:XP_011517511.1|ensembl:ENSG00000119139(gene)|ensembl:ENST00000377245(transcript)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034109"(homotypic cell-cell adhesion)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050892"(intestinal absorption)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR005417(Zona occludens protein)|interpro:IPR005419(Zona occludens protein ZO-2)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR035598|interpro:IPR036028|interpro:IPR036034|mint:Q9UDY2|rcsb pdb:2OSG|rcsb pdb:3E17|reactome:R-HSA-2028269|reactome:R-HSA-351906|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:iN/EF8QWKtekoj5eON764eKAdpg9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9UBU9	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-398874|uniprotkb:Q99799|uniprotkb:Q9UQL2|uniprotkb:B4E269|ensembl:ENSP00000436679|ensembl:ENSP00000294172	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:nxf1_human(display_long)|uniprotkb:NXF1(gene name)|psi-mi:NXF1(display_short)|uniprotkb:TAP(gene name synonym)|uniprotkb:Tip-associating protein(gene name synonym)|uniprotkb:Tip-associated protein(gene name synonym)|uniprotkb:mRNA export factor TAP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001074960.1|refseq:NP_006353.2|ensembl:ENSP00000294172|ensembl:ENST00000531709|ensembl:ENSP00000453885|ensembl:ENSP00000436679|dip:DIP-31789N|ensembl:ENST00000294172(transcript)|ensembl:ENST00000532297(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015245(Tap, RNA-binding)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|interpro:IPR032710|interpro:IPR035979|mint:Q9UBU9|rcsb pdb:1FO1|rcsb pdb:1FT8|rcsb pdb:1GO5|rcsb pdb:1JKG|rcsb pdb:1JN5|rcsb pdb:1KOH|rcsb pdb:1KOO|rcsb pdb:1OAI|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:3RW6|rcsb pdb:3RW7|rcsb pdb:4WYK|rcsb pdb:6E5U|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|ensembl:ENSG00000162231(gene)	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:a983QBMgsm07FV/IcYsO37Sk0hU9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9P2E9	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2371806|uniprotkb:A2A2S6|uniprotkb:A6NCN6|uniprotkb:O75300|uniprotkb:O75301|uniprotkb:Q5W165|uniprotkb:Q96SB2|uniprotkb:Q9BWP1|uniprotkb:Q9H476|uniprotkb:A0A0A0MRV0|intact:EBI-28985482|ensembl:ENSP00000246043|ensembl:ENSP00000367044	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:rrbp1_human(display_long)|uniprotkb:RRBP1(gene name)|psi-mi:RRBP1(display_short)|uniprotkb:KIAA1398(gene name synonym)|uniprotkb:Ribosome receptor protein(gene name synonym)|uniprotkb:180 kDa ribosome receptor homolog(gene name synonym)|uniprotkb:ES/130-related protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001036041.1|refseq:NP_004578.2|ensembl:ENSP00000246043|ensembl:ENST00000360807|ensembl:ENSP00000354045|ensembl:ENST00000377807|ensembl:ENSP00000367038|ensembl:ENSP00000367044|ensembl:ENSG00000125844(gene)|ensembl:ENST00000246043(transcript)|ensembl:ENST00000377813(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR007794(Ribosome receptor lysine or proline rich)|interpro:IPR040248|mint:Q9P2E9	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:uOiVzIAM5bsSl2s1BSIfnUtZ3Ms9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9NZJ9	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-4280066|uniprotkb:B7Z916|uniprotkb:Q4AEJ6|uniprotkb:Q53EZ2|uniprotkb:Q68DD7|uniprotkb:Q9NPC5|uniprotkb:Q9NS30|uniprotkb:Q9NZK0|uniprotkb:Q9NZK1|ensembl:ENSP00000406612	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:nudt4_human(display_long)|uniprotkb:NUDT4(gene name)|psi-mi:NUDT4(display_short)|uniprotkb:DIPP2(gene name synonym)|uniprotkb:KIAA0487(gene name synonym)|uniprotkb:Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 2(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 4(gene name synonym)|uniprotkb:HDCMB47P(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_061967.3|refseq:NP_950241.1|refseq:NP_001287951.1|refseq:NP_001287952.1|refseq:NP_001287953.1|refseq:XP_011536096.1|refseq:XP_011536097.1|refseq:XP_011536098.1|ensembl:ENSG00000173598(gene)|ensembl:ENST00000415493(transcript)|go:"GO:0000298"(endopolyphosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008486"(diphosphoinositol-polyphosphate diphosphatase activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019935"(cyclic-nucleotide-mediated signaling)|go:"GO:0030515"(snoRNA binding)|go:"GO:0034431"("bis(5'-adenosyl)-hexaphosphatase activity")|go:"GO:0034432"("bis(5'-adenosyl)-pentaphosphatase activity")|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0052840"(inositol diphosphate tetrakisphosphate diphosphatase activity)|go:"GO:0052842"(inositol diphosphate pentakisphosphate diphosphatase activity)|go:"GO:0071543"(diphosphoinositol polyphosphate metabolic process)|go:"GO:1901907"(diadenosine pentaphosphate catabolic process)|go:"GO:1901909"(diadenosine hexaphosphate catabolic process)|go:"GO:1901911"("adenosine 5'-(hexahydrogen pentaphosphate) catabolic process")|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR020084|mint:Q9NZJ9|rcsb pdb:5LTU|reactome:R-HSA-1855167|interpro:IPR015797(NUDIX)	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:IhccOdCGReMByDtHvil7eg9Jgao9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9HD20	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-3940599|uniprotkb:B3KTA7|uniprotkb:B3KPJ2|uniprotkb:Q9H6C6|ensembl:ENSP00000349877|uniprotkb:Q6NT90|uniprotkb:Q6ZMG7	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:at131_human(display_long)|uniprotkb:ATP13A1(gene name)|psi-mi:ATP13A1(display_short)|uniprotkb:ATP13A(gene name synonym)|uniprotkb:KIAA1825(gene name synonym)|uniprotkb:CGI-152(orf name)|uniprotkb:Endoplasmic reticulum P5A-ATPase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSG00000105726(gene)|ensembl:ENST00000357324(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0140567"(transmembrane protein dislocase activity)|go:"GO:0140569"(extraction of mislocalized protein from ER membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006544("P-type ATPase of unknown pump specificity (type V)")|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q9HD20|reactome:R-HSA-936837|go:"GO:0015410"(ABC-type manganese transporter activity)|refseq:NP_065143.2	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:p4PEgZhH5QhoHI+InDMbLvdIBP09606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9H334	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-983809|uniprotkb:Q9H332|uniprotkb:Q9H333|uniprotkb:Q9P0R1|intact:EBI-28984754|ensembl:ENSP00000318902|ensembl:ENSP00000418102|ensembl:ENSP00000419393|ensembl:ENSP00000496990|ensembl:ENSP00000497344|ensembl:ENSP00000497369|uniprotkb:A3QVP8|uniprotkb:Q9BSG9|uniprotkb:B3KV70|uniprotkb:G5E9V8|uniprotkb:Q8NAN6	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:foxp1_human(display_long)|uniprotkb:FOXP1(gene name)|psi-mi:FOXP1(display_short)|uniprotkb:Mac-1-regulated forkhead(gene name synonym)|uniprotkb:HSPC215(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:XP_006713165.1|refseq:XP_006713166.1|refseq:XP_006713167.1|go:"GO:0032655"(regulation of interleukin-12 production)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0032651"(regulation of interleukin-1 beta production)|go:"GO:0032745"(positive regulation of interleukin-21 production)|go:"GO:0036035"(osteoclast development)|go:"GO:0042116"(macrophage activation)|go:"GO:0042117"(monocyte activation)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045655"(regulation of monocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050727"(regulation of inflammatory response)|ensembl:ENSG00000114861(gene)|ensembl:ENST00000318789(transcript)|ensembl:ENST00000475937(transcript)|ensembl:ENST00000498215(transcript)|ensembl:ENST00000648380(transcript)|ensembl:ENST00000649528(transcript)|ensembl:ENST00000649631(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|rcsb pdb:2KIU|reactome:R-HSA-452723|mint:Q9H334|go:"GO:0050861"(positive regulation of B cell receptor signaling pathway)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0061470"(T follicular helper cell differentiation)|go:"GO:1900424"(regulation of defense response to bacterium)|go:"GO:1901256"(regulation of macrophage colony-stimulating factor production)|go:"GO:1901509"(regulation of endothelial tube morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000341"("regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR032354|interpro:IPR036388|interpro:IPR036390|refseq:XP_011531886.1|refseq:XP_011531887.1|refseq:NP_116071.2|refseq:NP_001231743.1|refseq:NP_001231745.1|refseq:NP_001231744.1|refseq:NP_001012523.1|ensembl:ENST00000318779|ensembl:ENSP00000318721|ensembl:ENSP00000318902|ensembl:ENSP00000419393|ensembl:ENST00000484350|ensembl:ENSP00000417857|ensembl:ENST00000493089|ensembl:ENSP00000418524|ensembl:ENSP00000418102|ensembl:ENST00000615603|ensembl:ENSP00000484803|ensembl:ENST00000622151|ensembl:ENSP00000477918|ensembl:ENST00000648107|ensembl:ENSP00000497914|ensembl:ENSP00000497344|ensembl:ENST00000648426|ensembl:ENSP00000498110|ensembl:ENST00000648662|ensembl:ENSP00000496873|ensembl:ENST00000648718|ensembl:ENSP00000496810|ensembl:ENSP00000497369|ensembl:ENSP00000496990|ensembl:ENST00000674446|ensembl:ENSP00000501439|dip:DIP-36585N|refseq:XP_016861654.1|refseq:XP_016861655.1|refseq:XP_016861657.1|refseq:NP_001231741.1|refseq:NP_001231737.1|refseq:NP_001231739.1	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:NREo12e1TLPfsul6Ie0l62NqIa89606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9H2W6	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-6393565|ensembl:ENSP00000312311|uniprotkb:B2RD75|uniprotkb:Q9HBU8	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:rm46_human(display_long)|uniprotkb:Mitochondrial large ribosomal subunit protein mL46(gene name synonym)|uniprotkb:MRPL46(gene name)|psi-mi:MRPL46(display_short)|uniprotkb:C15orf4(gene name synonym)|uniprotkb:LIECG2(gene name synonym)|uniprotkb:P2ECSL(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSG00000259494(gene)|ensembl:ENST00000312475(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030054"(cell junction)|interpro:IPR015797(NUDIX)|interpro:IPR021757|interpro:IPR033650|interpro:IPR040008|mint:Q9H2W6|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|rcsb pdb:7A5K|reactome:R-HSA-5419276|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|refseq:NP_071446.2	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:7u4sNH/MVFnEZRMjr7ey6d8WpfM9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9H2U1	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1047643|uniprotkb:Q70JU3|uniprotkb:Q8IYE5|uniprotkb:Q9P240|uniprotkb:B2RB00|ensembl:ENSP00000417078	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:dhx36_human(display_long)|uniprotkb:DEAD/H box polypeptide 36(gene name synonym)|uniprotkb:DEAH-box protein 36(gene name synonym)|uniprotkb:G4-resolvase-1(gene name synonym)|uniprotkb:RNA helicase associated with AU-rich element protein(gene name synonym)|uniprotkb:MLE-like protein 1(gene name synonym)|uniprotkb:DHX36(gene name)|psi-mi:DHX36(display_short)|uniprotkb:DDX36(gene name synonym)|uniprotkb:KIAA1488(gene name synonym)|uniprotkb:MLEL1(gene name synonym)|uniprotkb:RHAU(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001107869.1|refseq:NP_065916.2|go:"GO:0006359"(regulation of transcription by RNA polymerase III)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034644"(cellular response to UV)|go:"GO:0005829"(cytosol)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043204"(perikaryon)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070883"(pre-miRNA binding)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|go:"GO:0090669"(telomerase RNA stabilization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901534"(positive regulation of hematopoietic progenitor cell differentiation)|go:"GO:1902064"(regulation of transcription from RNA polymerase II promoter involved in spermatogenesis)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1904582"(positive regulation of intracellular mRNA localization)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR027417|ensembl:ENSG00000174953(gene)|ensembl:ENST00000496811(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001503"(ossification)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0002735"(positive regulation of myeloid dendritic cell cytokine production)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|rcsb pdb:2N16|rcsb pdb:2N21|rcsb pdb:6Q6R|reactome:R-HSA-3134963|mint:Q9H2U1	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:CvYmO1OB0zu5ZCYzQmKvCYGc3+k9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9H269	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2655929|uniprotkb:Q5JUB1|uniprotkb:Q8WU31|uniprotkb:Q96EE7|uniprotkb:Q96N92|uniprotkb:Q9H1Q4|uniprotkb:Q9H1Q5|ensembl:ENSP00000369810	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:vps16_human(display_long)|uniprotkb:VPS16(gene name)|psi-mi:VPS16(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_072097.2|refseq:NP_536338.1|ensembl:ENSG00000215305(gene)|ensembl:ENST00000380445(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030424"(axon)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051015"(actin filament binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR006925(Vps16, C-terminal)|interpro:IPR006926(Vps16, N-terminal)|interpro:IPR016534(Vacuolar protein sorting-associated protein 16)|interpro:IPR038132|mint:Q9H269|rcsb pdb:4BX9	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:bm088LmFRv3w0wfvlPMFeottZkw9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9H0D6	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-372110|uniprotkb:Q3L8N4|uniprotkb:Q6KGZ9|uniprotkb:Q9BQL1|uniprotkb:Q9NTW0|uniprotkb:Q9NXS6|uniprotkb:Q9UL53|ensembl:ENSP00000366396	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:xrn2_human(display_long)|uniprotkb:XRN2(gene name)|psi-mi:XRN2(display_short)|uniprotkb:DHM1-like protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_036387.2|refseq:NP_001304889.1|ensembl:ENSG00000088930(gene)|ensembl:ENST00000377191(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000738"(DNA catabolic process, exonucleolytic)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0016020"(membrane)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060041"(retina development in camera-type eye)|interpro:IPR004859(Putative 5-3 exonuclease)|interpro:IPR017151(5'-3' exoribonuclease 2)|interpro:IPR027073|interpro:IPR041412|mint:Q9H0D6|reactome:R-HSA-390471|reactome:R-HSA-6791226|dip:DIP-31166N	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:Ui0NiU+fGe68hK5CYTolkhioQbQ9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9H089	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-4402486|uniprotkb:A0JLT4|uniprotkb:A0PJK3|uniprotkb:A6NI18|uniprotkb:Q7L9H8|uniprotkb:Q9NUK8|ensembl:ENSP00000265245	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:lsg1_human(display_long)|uniprotkb:LSG1(gene name)|psi-mi:LSG1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_060855.2|ensembl:ENSG00000041802(gene)|ensembl:ENST00000265245(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0051168"(nuclear export)|interpro:IPR006073(GTP1/OBG)|interpro:IPR027417|interpro:IPR030378|interpro:IPR043358|mint:Q9H089|rcsb pdb:6LSR	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:66YYrxhw+MOGH9+lyrsQ4JPDA3w9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9BZH6	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2009923|uniprotkb:Q5VWA1|uniprotkb:Q9P2J6|ensembl:ENSP00000263461	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:wdr11_human(display_long)|uniprotkb:WDR11(gene name)|psi-mi:WDR11(display_short)|uniprotkb:KIAA1351(gene name synonym)|uniprotkb:BRWD2(gene name synonym)|uniprotkb:WDR15(gene name synonym)|uniprotkb:Bromodomain and WD repeat-containing protein 2(gene name synonym)|uniprotkb:WD repeat-containing protein 15(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_060587.8|ensembl:ENSG00000120008(gene)|ensembl:ENST00000263461(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007507"(heart development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:0060322"(head development)|go:"GO:0099041"(vesicle tethering to Golgi)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR039694|mint:Q9BZH6|reactome:R-HSA-9013407	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:Kl337t8mCHvvkb8oi0z8Ohl72a09606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9BZF1	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2684038|uniprotkb:Q52LQ3|uniprotkb:Q9P277|uniprotkb:Q8WXP8|uniprotkb:A8K1T2|uniprotkb:E9PE66|uniprotkb:E9PE68|uniprotkb:Q68D75|ensembl:ENSP00000261183	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:osbl8_human(display_long)|uniprotkb:KIAA1451(gene name synonym)|uniprotkb:ORP8(gene name synonym)|uniprotkb:OSBP10(gene name synonym)|uniprotkb:OSBPL8(gene name)|psi-mi:OSBPL8(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001003712.1|refseq:NP_065892.1|refseq:NP_001306581.1|refseq:NP_001306584.1|ensembl:ENSG00000091039(gene)|ensembl:ENST00000261183(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015914"(phospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0036150"(phosphatidylserine acyl-chain remodeling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0090204"(protein localization to nuclear pore)|go:"GO:0140343"(phosphatidylserine transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|mint:Q9BZF1|rcsb pdb:1V88|rcsb pdb:5U77|rcsb pdb:5U78|reactome:R-HSA-1482801|refseq:XP_005268678.1|refseq:XP_006719287.1|dip:DIP-56130N	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:KwZ5DFeGTIM3p/yP3XBNgr/v3O09606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9BVI4	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-395927|uniprotkb:Q8N2S5|uniprotkb:Q96I14|ensembl:ENSP00000328854|ensembl:ENSP00000500901	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:noc4l_human(display_long)|uniprotkb:NOC4-like protein(gene name synonym)|uniprotkb:Nucleolar complex-associated protein 4-like protein(gene name synonym)|uniprotkb:NOC4L(gene name)|psi-mi:NOC4L(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_076983.1|ensembl:ENSG00000184967(gene)|ensembl:ENSG00000288146(gene)|ensembl:ENST00000330579(transcript)|ensembl:ENST00000672504(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030692"(Noc4p-Nop14p complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032040"(small-subunit processome)|interpro:IPR005612(CBF)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027193|mint:Q9BVI4|reactome:R-HSA-6790901|reactome:R-HSA-6791226|dip:DIP-32938N	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:PczuDyeVf4oAGktQfOSfHWmrCwA9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9BVC6	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1057733|ensembl:ENSP00000227525|ensembl:ENSP00000443990	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:tm109_human(display_long)|uniprotkb:TMEM109(gene name)|psi-mi:TMEM109(display_short)|uniprotkb:Mitsugumin-23(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_076997.1|ensembl:ENSG00000110108(gene)|ensembl:ENST00000227525(transcript)|ensembl:ENST00000536171(transcript)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|interpro:IPR039492|mint:Q9BVC6	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:KsibbFWmzuiZPpo4GqJikbMMaMQ9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q96S19	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-26610662|ensembl:ENSP00000445926|uniprotkb:A8MTR1|uniprotkb:A8MWJ8|uniprotkb:A8MZA1|uniprotkb:B4DG95|uniprotkb:B4DIJ3|uniprotkb:D6REA6|uniprotkb:F6TF62|uniprotkb:F6VM53|uniprotkb:Q96IW1|uniprotkb:Q96MD6	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:mtl26_human(display_long)|uniprotkb:METTL26(gene name)|psi-mi:METTL26(display_short)|uniprotkb:JFP2(gene name synonym)|uniprotkb:C16orf13(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSG00000130731(gene)|ensembl:ENST00000301686(transcript)|interpro:IPR010342(Protein of unknown function DUF938)|interpro:IPR029063|mint:Q96S19|refseq:NP_001035250.1|refseq:NP_001035251.1|refseq:NP_001035252.1|refseq:NP_001035255.1|refseq:NP_115742.3	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:y6h76HyfGwupjx4FuVc+akqqcoo9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q96PK6	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-954272|ensembl:ENSP00000311747|uniprotkb:O75932|uniprotkb:Q53GV1|uniprotkb:Q68DQ9|uniprotkb:Q96PK5|uniprotkb:B3KMN4|uniprotkb:Q2PYN1|uniprotkb:D6RGD8|uniprotkb:B0LM41|intact:EBI-16430855|intact:EBI-16472484	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:rbm14_human(display_long)|uniprotkb:RNA-binding motif protein 14(gene name synonym)|uniprotkb:RRM-containing coactivator activator/modulator(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein(gene name synonym)|uniprotkb:RBM14(gene name)|psi-mi:RBM14(display_short)|uniprotkb:SIP(gene name synonym)|uniprotkb:Paraspeckle protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSG00000239306(gene)|ensembl:ENST00000310137(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009725"(response to hormone)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034506|interpro:IPR034507|go:"GO:0098534"(centriole assembly)|interpro:IPR035979|mint:Q96PK6|rcsb pdb:2DNP|reactome:R-HSA-8941326|refseq:NP_001185765.1|refseq:NP_006319.1|ensembl:ENSP00000311747|ensembl:ENST00000393979|ensembl:ENSP00000377548|ensembl:ENST00000409738|ensembl:ENSP00000386995|refseq:NP_001185766.1|refseq:NP_001185774.1|dip:DIP-50126N	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:Q0UBl2qmfwQTPwUQ7ZDwGIMOYoA9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q96P70	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-356319|intact:EBI-1059309|uniprotkb:Q8N1Y1|uniprotkb:Q8N3I2|uniprotkb:Q8NCG9|uniprotkb:Q96SU6|uniprotkb:Q9NW01|uniprotkb:Q9P0A8|uniprotkb:Q9ULM8|ensembl:ENSP00000354742|uniprotkb:B1ASV5	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:ipo9_human(display_long)|uniprotkb:HSPC273(orf name)|uniprotkb:IPO9(gene name)|psi-mi:IPO9(display_short)|uniprotkb:IMP9(gene name synonym)|uniprotkb:KIAA1192(gene name synonym)|uniprotkb:RANBP9(gene name synonym)|uniprotkb:Ran-binding protein 9(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_060555.2|ensembl:ENSG00000198700(gene)|ensembl:ENST00000361565(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042393"(histone binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|mint:Q96P70|rcsb pdb:6N1Z	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:jsjQSBULeF1L2FlDcPZouMz6pJE9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q96AQ6	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-740845|ensembl:ENSP00000357448|intact:EBI-1210745|uniprotkb:Q5T174|uniprotkb:Q5T176|uniprotkb:Q9H8X6|uniprotkb:Q9HA02|uniprotkb:Q9HD85	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:pbip1_human(display_long)|uniprotkb:PBXIP1(gene name)|psi-mi:PBXIP1(display_short)|uniprotkb:HPIP(gene name synonym)|uniprotkb:Hematopoietic PBX-interacting protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_065385.2|ensembl:ENSG00000163346(gene)|ensembl:ENST00000368463(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002532"(production of molecular mediator involved in inflammatory response)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007155"(cell adhesion)|go:"GO:0007275"(multicellular organism development)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0061975"(articular cartilage development)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:1901148"(gene expression involved in extracellular matrix organization)|go:"GO:1902732"(positive regulation of chondrocyte proliferation)|go:"GO:2001106"(regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR033589|mint:Q96AQ6|refseq:NP_001304663.1|refseq:NP_001304664.1|dip:DIP-46922N	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:YQJMW+FdeTJMqyFn8+M0TY3qPkw9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q93009	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-302474|uniprotkb:A6NMY8|intact:EBI-28988230|ensembl:ENSP00000343535|uniprotkb:B7Z815|uniprotkb:H0Y3G8	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:ubp7_human(display_long)|uniprotkb:USP7(gene name)|psi-mi:USP7(display_short)|uniprotkb:HAUSP(gene name synonym)|uniprotkb:Ubiquitin thioesterase 7(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 7(gene name synonym)|uniprotkb:Deubiquitinating enzyme 7(gene name synonym)|uniprotkb:Herpesvirus-associated ubiquitin-specific protease(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	rcsb pdb:4PYZ|rcsb pdb:4WPH|rcsb pdb:4WPI|rcsb pdb:4YOC|rcsb pdb:4YSI|rcsb pdb:4Z96|rcsb pdb:4Z97|rcsb pdb:5C56|rcsb pdb:5C6D|rcsb pdb:5FWI|rcsb pdb:5GG4|rcsb pdb:5J7T|rcsb pdb:5JTJ|rcsb pdb:5JTV|rcsb pdb:5KYB|rcsb pdb:4M5X|rcsb pdb:5KYC|rcsb pdb:5KYD|rcsb pdb:5KYE|rcsb pdb:5KYF|interpro:IPR029346|interpro:IPR038765|mint:Q93009|rcsb pdb:1NB8|rcsb pdb:1NBF|rcsb pdb:1YY6|rcsb pdb:1YZE|rcsb pdb:2F1W|rcsb pdb:2F1X|rcsb pdb:2F1Y|rcsb pdb:2F1Z|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2FOP|rcsb pdb:2KVR|rcsb pdb:2XXN|rcsb pdb:2YLM|rcsb pdb:3MQR|rcsb pdb:3MQS|rcsb pdb:4JJQ|rcsb pdb:4KG9|rcsb pdb:4M5W|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050821"(protein stabilization)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904353"(regulation of telomere capping)|go:"GO:1905279"(regulation of retrograde transport, endosome to Golgi)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR018200|interpro:IPR024729|interpro:IPR028889|ensembl:ENSG00000187555(gene)|ensembl:ENST00000344836(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|rcsb pdb:5N9R|rcsb pdb:5N9T|rcsb pdb:5NGE|rcsb pdb:5NGF|rcsb pdb:5UQV|rcsb pdb:5UQX|rcsb pdb:5VS6|rcsb pdb:5VSB|rcsb pdb:5VSK|rcsb pdb:5WHC|rcsb pdb:6F5H|rcsb pdb:6M1K|rcsb pdb:6P5L|rcsb pdb:6VN2|rcsb pdb:6VN3|rcsb pdb:6VN4|rcsb pdb:6VN5|rcsb pdb:6VN6|rcsb pdb:7CM2|reactome:R-HSA-5689880|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804757|reactome:R-HSA-8866652|reactome:R-HSA-8948747|refseq:NP_001273386.1|refseq:NP_003461.2|refseq:NP_001308787.1|ensembl:ENSP00000343535|ensembl:ENST00000381886|ensembl:ENSP00000371310|dip:DIP-29053N	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:V+PXXBRM2zwlGQaeFiyjaQ9yf+A9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q92673	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1171329|uniprotkb:Q92856|uniprotkb:B2RNX7|ensembl:ENSP00000260197	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:sorl_human(display_long)|uniprotkb:Sorting protein-related receptor containing LDLR class A repeats(gene name synonym)|uniprotkb:SorLA-1(gene name synonym)|uniprotkb:Low-density lipoprotein receptor relative with 11 ligand-binding repeats(gene name synonym)|uniprotkb:SORL1(gene name)|psi-mi:SORL1(display_short)|uniprotkb:C11orf32(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_003096.1|ensembl:ENSG00000137642(gene)|ensembl:ENST00000260197(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0002024"(diet induced thermogenesis)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010897"(negative regulation of triglyceride catabolic process)|go:"GO:0014910"(regulation of smooth muscle cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0038020"(insulin receptor recycling)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045053"(protein retention in Golgi apparatus)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051604"(protein maturation)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:0097356"(perinucleolar compartment)|go:"GO:1900168"(positive regulation of glial cell-derived neurotrophic factor production)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902771"(positive regulation of choline O-acetyltransferase activity)|go:"GO:1902948"(negative regulation of tau-protein kinase activity)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|go:"GO:1902955"(positive regulation of early endosome to recycling endosome transport)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1902963"(negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1902997"(negative regulation of neurofibrillary tangle assembly)|go:"GO:1904179"(positive regulation of adipose tissue development)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006581(VPS10)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR023415|interpro:IPR031777|interpro:IPR031778|interpro:IPR036055|interpro:IPR036116|mint:Q92673|rcsb pdb:2DM4|rcsb pdb:3G2S|rcsb pdb:3G2T|rcsb pdb:3WSX|rcsb pdb:3WSY|rcsb pdb:3WSZ|reactome:R-HSA-977225|go:"GO:2001137"(positive regulation of endocytic recycling)|dip:DIP-41229N	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:JoB0wm+nsEc1vhUsfcaOrc9YwMc9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q92620	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1043041|uniprotkb:O75212|uniprotkb:Q96HN7|ensembl:ENSP00000268482|uniprotkb:D3DWS7|uniprotkb:B4DVG8	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:prp16_human(display_long)|uniprotkb:DHX38(gene name)|psi-mi:DHX38(display_short)|uniprotkb:DDX38(gene name synonym)|uniprotkb:KIAA0224(gene name synonym)|uniprotkb:PRP16(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DHX38(gene name synonym)|uniprotkb:DEAH box protein 38(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSG00000140829(gene)|ensembl:ENST00000268482(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0016020"(membrane)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|mint:Q92620|rcsb pdb:5YZG|rcsb pdb:6ZYM|rcsb pdb:7A5P|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|refseq:NP_054722.2|refseq:XP_011521786.1|refseq:XP_011521787.1	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:miHZNGhDUIz9imwhlPz2tIsCNLs9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q8WXI9	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-923440|uniprotkb:Q5VUR2|uniprotkb:Q7LG68|uniprotkb:Q9ULS0|uniprotkb:D3DUZ2|ensembl:ENSP00000357644|ensembl:ENSP00000458280|ensembl:ENSP00000489184	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:p66b_human(display_long)|uniprotkb:GATAD2B(gene name)|psi-mi:GATAD2B(display_short)|uniprotkb:KIAA1150(gene name synonym)|uniprotkb:p66/p68(gene name synonym)|uniprotkb:GATA zinc finger domain-containing protein 2B(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_065750.1|refseq:XP_005245421.1|dip:DIP-36054N|ensembl:ENSG00000143614(gene)|ensembl:ENSG00000261992(gene)|ensembl:ENST00000368655(transcript)|ensembl:ENST00000576342(transcript)|ensembl:ENST00000634544(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR032346|interpro:IPR040386|mint:Q8WXI9|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:pLKkMcJBBWdyMTf+2axWzvZLKP09606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q8TEM1	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-372826|uniprotkb:A6NN56|uniprotkb:O94980|uniprotkb:Q6NXG6|uniprotkb:Q8NBJ1|uniprotkb:Q9H6C8|uniprotkb:Q9UFP3|ensembl:ENSP00000254508	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:po210_human(display_long)|uniprotkb:KIAA0906(gene name synonym)|uniprotkb:NUP210(gene name)|psi-mi:NUP210(display_short)|uniprotkb:PSEC0245(orf name)|uniprotkb:Nuclear envelope pore membrane protein POM 210(gene name synonym)|uniprotkb:Pore membrane protein of 210 kDa(gene name synonym)|uniprotkb:Nucleoporin Nup210(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	reactome:R-HSA-9610379|refseq:NP_079199.2|ensembl:ENSG00000132182(gene)|ensembl:ENST00000254508(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR003343(Bacterial Ig-like, group 2)|interpro:IPR008964(Invasin/intimin cell-adhesion)|mint:Q8TEM1|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:udIemFThWYk0VC21Ml4EDDQWXlg9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q8TEA8	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-4287111|uniprotkb:A8K5X5|uniprotkb:D3DW37|uniprotkb:Q496D1|uniprotkb:Q5W184|uniprotkb:Q8WXU8|uniprotkb:Q9BW67|uniprotkb:Q9H464|uniprotkb:Q9H474|ensembl:ENSP00000366672	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:dtd1_human(display_long)|uniprotkb:DTD1(gene name)|psi-mi:DTD1(display_short)|uniprotkb:C20orf88(gene name synonym)|uniprotkb:HARS2(gene name synonym)|uniprotkb:Histidyl-tRNA synthase-related(gene name synonym)|uniprotkb:"Gly-tRNA(Ala) deacylase"(gene name synonym)|uniprotkb:DNA-unwinding element-binding protein B(gene name synonym)|uniprotkb:DUEB(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_543010.3|refseq:NP_001304972.1|interpro:IPR023509|mint:Q8TEA8|rcsb pdb:2OKV|ensembl:ENSG00000125821(gene)|ensembl:ENST00000377452(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006399"(tRNA metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051500"("D-tyrosyl-tRNA(Tyr) deacylase activity")|interpro:IPR003732("D-tyrosyl-tRNA(Tyr) deacylase")	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:xv8w85tCe2A1hPgsPS6wG3peR7I9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q8N766	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q8N684	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-746909|uniprotkb:C9K0Q4|uniprotkb:Q7Z3H9|uniprotkb:Q9H025|uniprotkb:Q9H9V1|uniprotkb:B3KU04|ensembl:ENSP00000378352	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:cpsf7_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 59 kDa subunit(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 59 kDa subunit(gene name synonym)|uniprotkb:CPSF7(gene name)|psi-mi:CPSF7(display_short)|uniprotkb:Cleavage factor Im complex 59 kDa subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001129512.1|refseq:NP_001136037.1|refseq:NP_079087.3|refseq:XP_011543560.1|refseq:XP_011543561.1|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0016020"(membrane)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034770|interpro:IPR034772|interpro:IPR034773|interpro:IPR035979|mint:Q8N684|rcsb pdb:3N9U|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|ensembl:ENSG00000149532(gene)|ensembl:ENST00000394888(transcript)|refseq:XP_005274356.1|reactome:R-HSA-9013422	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:bfliZhw27GRZMSQpYRZ/x/tWGh49606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q8N5Z5	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-743960|uniprotkb:B0QYA9|uniprotkb:B0QYB0|uniprotkb:O95517|ensembl:ENSP00000385096	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:kcd17_human(display_long)|uniprotkb:KCTD17(gene name)|psi-mi:KCTD17(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001269613.1|refseq:NP_001269614.1|refseq:NP_001269615.1|refseq:NP_078957.2|ensembl:ENSG00000100379(gene)|ensembl:ENST00000403888(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030030"(cell projection organization)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q8N5Z5|rcsb pdb:5A6R	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:998kw0bw9dTtZQYgdqYCNxIKG0w9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q8N3E9	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-4290990|uniprotkb:Q8TEC1|uniprotkb:Q8TF37|uniprotkb:Q96FL6|ensembl:ENSP00000479636	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:plcd3_human(display_long)|uniprotkb:PLCD3(gene name)|psi-mi:PLCD3(display_short)|uniprotkb:KIAA1964(gene name synonym)|uniprotkb:Phosphoinositide phospholipase C-delta-3(gene name synonym)|uniprotkb:Phospholipase C-delta-3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_588614.1|ensembl:ENSG00000161714(gene)|ensembl:ENST00000619929(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0060716"(labyrinthine layer blood vessel development)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000909(Phospholipase C, phosphatidylinositol-specific , X region)|interpro:IPR001192("Phospholipase C, phosphoinositol-specific, C-terminal (PLC)")|interpro:IPR001711(Phospholipase C, phosphatidylinositol-specific, Y domain)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017946|interpro:IPR018247|interpro:IPR028406|interpro:IPR035892|interpro:IPR039504|mint:Q8N3E9|reactome:R-HSA-1855204|go:"GO:0046872"(metal ion binding)	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:XZPO9hcwz/PmSdnF7h5dZ50m15M9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q8IYK4	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-10263496|uniprotkb:Q9BZR0|uniprotkb:O60327|ensembl:ENSP00000354960	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:gt252_human(display_long)|uniprotkb:COLGALT2(gene name)|psi-mi:COLGALT2(display_short)|uniprotkb:C1orf17(gene name synonym)|uniprotkb:"Collagen beta(1-O)galactosyltransferase 2"(gene name synonym)|uniprotkb:GLT25D2(gene name synonym)|uniprotkb:Glycosyltransferase 25 family member 2(gene name synonym)|uniprotkb:Hydroxylysine galactosyltransferase 2(gene name synonym)|uniprotkb:KIAA0584(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001290349.1|refseq:NP_001290350.1|refseq:NP_055916.1|ensembl:ENSG00000198756(gene)|ensembl:ENST00000361927(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0050211"(procollagen galactosyltransferase activity)|interpro:IPR002654(Glycosyl transferase, family 25)|interpro:IPR029044|mint:Q8IYK4|reactome:R-HSA-1650814	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:4psvO3s6JSJzfZyeUcEjduMLFNw9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q8IWT6	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-10970086|ensembl:ENSP00000259324|ensembl:ENSP00000361680|ensembl:ENSP00000361682|uniprotkb:Q9P2B1|uniprotkb:Q8NCI0|uniprotkb:Q6UXM2	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:lrc8a_human(display_long)|uniprotkb:LRRC8A(gene name)|psi-mi:LRRC8A(display_short)|uniprotkb:KIAA1437(gene name synonym)|uniprotkb:LRRC8(gene name synonym)|uniprotkb:Leucine-rich repeat-containing protein 8A(gene name synonym)|uniprotkb:SWELL1(gene name synonym)|uniprotkb:Swelling protein 1(gene name synonym)|uniprotkb:UNQ221/PRO247(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001120716.1|refseq:NP_001120717.1|refseq:NP_062540.2|refseq:XP_005252152.1|refseq:XP_005252153.1|refseq:XP_006717249.1|refseq:XP_011517165.1|refseq:XP_011517166.1|refseq:XP_011517167.1|ensembl:ENSG00000136802(gene)|ensembl:ENST00000259324(transcript)|ensembl:ENST00000372599(transcript)|ensembl:ENST00000372600(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0002329"(pre-B cell differentiation)|go:"GO:0005225"(volume-sensitive anion channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006820"(anion transport)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0015734"(taurine transport)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0034214"(protein hexamerization)|go:"GO:0034702"(ion channel complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0098656"(anion transmembrane transport)|go:"GO:0140360"(cyclic-GMP-AMP transmembrane transporter activity)|go:"GO:0140361"(cyclic-GMP-AMP transmembrane import across plasma membrane)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR021040|interpro:IPR032675|mint:Q8IWT6|rcsb pdb:5ZSU|rcsb pdb:6DJB|reactome:R-HSA-5223345|dip:DIP-61360N	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:4+VhpXqOjBfbrNagOqJ7eY/qy+s9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q86XP3	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-722353|uniprotkb:A6NML1|uniprotkb:O75619|uniprotkb:Q68G51|uniprotkb:Q96BK1|uniprotkb:Q96HR7|uniprotkb:Q9Y3V8|uniprotkb:A8KA43|intact:EBI-2555393|ensembl:ENSP00000374574|ensembl:ENSP00000463561|ensembl:ENSP00000464050	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:ddx42_human(display_long)|uniprotkb:DEAD box protein 42(gene name synonym)|uniprotkb:Splicing factor 3B-associated 125 kDa protein(gene name synonym)|uniprotkb:RNA helicase-related protein(gene name synonym)|uniprotkb:RNA helicase-like protein(gene name synonym)|uniprotkb:SF3b DEAD box protein(gene name synonym)|uniprotkb:DDX42(gene name)|psi-mi:DDX42(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_031398.2|refseq:NP_987095.1|refseq:XP_006721720.1|refseq:XP_016879600.1|ensembl:ENSG00000198231(gene)|ensembl:ENST00000389924(transcript)|ensembl:ENST00000578681(transcript)|ensembl:ENST00000583590(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008104"(protein localization)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q86XP3|reactome:R-HSA-72163|reactome:R-HSA-72165	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:3vZn92rr6cO8qSZJdyq1fguSc489606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q86V81	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-347640|uniprotkb:O43672	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q86V48	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-350467|uniprotkb:Q5TH93|uniprotkb:Q8N4X3|uniprotkb:Q8TEH1|ensembl:ENSP00000303758|ensembl:ENSP00000393460	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:luzp1_human(display_long)|uniprotkb:LUZP1(gene name)|psi-mi:LUZP1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001136018.1|refseq:NP_361013.3|refseq:XP_011540392.1|refseq:XP_011540393.1|ensembl:ENSG00000169641(gene)|ensembl:ENST00000302291(transcript)|ensembl:ENST00000418342(transcript)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0016020"(membrane)|go:"GO:0021503"(neural fold bending)|go:"GO:0060840"(artery development)|go:"GO:0070062"(extracellular exosome)|interpro:IPR026734|mint:Q86V48|refseq:XP_016857741.1|dip:DIP-33113N	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:l456S0i3H1z5fv6M4SNkdrls/c49606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q86UE4	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1046588|ensembl:ENSP00000338235|uniprotkb:Q8TCX3|uniprotkb:Q6PK07|uniprotkb:Q05DH2|uniprotkb:Q52QU9	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:lyric_human(display_long)|uniprotkb:Lysine-rich CEACAM1 co-isolated protein(gene name synonym)|uniprotkb:3D3/LYRIC(gene name synonym)|uniprotkb:Metastasis adhesion protein(gene name synonym)|uniprotkb:Astrocyte elevated gene-1 protein(gene name synonym)|uniprotkb:MTDH(gene name)|psi-mi:MTDH(display_short)|uniprotkb:AEG1(gene name synonym)|uniprotkb:LYRIC(gene name synonym)|uniprotkb:Metadherin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSG00000147649(gene)|ensembl:ENST00000336273(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046581"(intercellular canaliculus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR031402|mint:Q86UE4|rcsb pdb:4QMG|refseq:NP_848927.2	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:daZhKhAOeoKGjfl0IXt1fZXn/I09606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q75T13	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1055128|uniprotkb:Q4G0R8|uniprotkb:Q4ZG47|uniprotkb:Q53SM0|uniprotkb:Q6AW92|uniprotkb:Q6UWV4|uniprotkb:Q9HA24|ensembl:ENSP00000346809	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:pgap1_human(display_long)|uniprotkb:Post-GPI attachment to proteins factor 1(gene name synonym)|uniprotkb:PGAP1(gene name)|psi-mi:PGAP1(display_short)|uniprotkb:UNQ3024/PRO9822(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001308028.1|refseq:NP_001308029.1|refseq:NP_079265.2|ensembl:ENSG00000197121(gene)|ensembl:ENST00000354764(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006505"(GPI anchor metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016255"(attachment of GPI anchor to protein)|go:"GO:0016788"(hydrolase activity, acting on ester bonds)|go:"GO:0021871"(forebrain regionalization)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0050185"(phosphatidylinositol deacylase activity)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|interpro:IPR012908(PGAP1-like)|interpro:IPR029058|interpro:IPR039529|mint:Q75T13|reactome:R-HSA-162791|refseq:XP_016860481.1|refseq:XP_016860482.1	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:mOh9dmfjLrZWaalO2QnERu+HPw49606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q70UQ0	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2557212|uniprotkb:Q96ND2|uniprotkb:Q86V91|uniprotkb:Q6ZWH4|uniprotkb:Q70UP9|ensembl:ENSP00000343471	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:ikip_human(display_long)|uniprotkb:IKIP(gene name synonym)|uniprotkb:IKBIP(gene name)|psi-mi:IKBIP(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSG00000166130(gene)|ensembl:ENST00000342502(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0010165"(response to X-ray)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR024152|mint:Q70UQ0|refseq:NP_710154.1|refseq:NP_963906.1|refseq:NP_963907.1	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:wUhuKhwmOyjUTYSF8or1Tc0Iu189606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q6UN15	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1021914|uniprotkb:Q0VGE0|uniprotkb:Q499Y4|uniprotkb:Q49AU3|uniprotkb:Q7Z608|uniprotkb:Q8WVN3|uniprotkb:Q96F80|uniprotkb:Q9H077|intact:EBI-11535474|ensembl:ENSP00000336752|uniprotkb:B4DIR3|uniprotkb:G3XAD6	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:fip1_human(display_long)|uniprotkb:Factor interacting with PAP(gene name synonym)|uniprotkb:FIP1-like 1 protein(gene name synonym)|uniprotkb:Rearranged in hypereosinophilia(gene name synonym)|uniprotkb:FIP1L1(gene name)|psi-mi:FIP1L1(display_short)|uniprotkb:FIP1(gene name synonym)|uniprotkb:RHE(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENST00000306932|ensembl:ENSP00000302993|ensembl:ENSP00000336752|ensembl:ENST00000358575|ensembl:ENSP00000351383|ensembl:ENST00000507922|ensembl:ENSP00000425456|refseq:NP_001128409.1|refseq:NP_001128410.1|refseq:NP_112179.2|ensembl:ENSG00000145216(gene)|ensembl:ENST00000337488(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR007854(Fip1)|mint:Q6UN15|rcsb pdb:7K95|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|reactome:R-HSA-9673766|dip:DIP-42503N	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:41uK1l8RV99q4k4Z7K9zeG3TJHA9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q6PD62	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1019583|uniprotkb:Q15015|uniprotkb:D3DQV8|ensembl:ENSP00000355013	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:ctr9_human(display_long)|uniprotkb:CTR9(gene name)|psi-mi:CTR9(display_short)|uniprotkb:KIAA0155(gene name synonym)|uniprotkb:SH2BP1(gene name synonym)|uniprotkb:SH2 domain-binding protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_055448.1|ensembl:ENSG00000198730(gene)|ensembl:ENST00000361367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001826"(inner cell mass cell differentiation)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001832"(blastocyst growth)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0035327"|go:"GO:0042169"(SH2 domain binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:2000653"(regulation of genetic imprinting)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031101|mint:Q6PD62|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|dip:DIP-31693N	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:zEFAxq/VxkK8za6qsK0gcU+EU8o9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q69YN4	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2819293|uniprotkb:Q9BTH4|uniprotkb:Q8IXH4|uniprotkb:Q6AHX9|uniprotkb:Q6NT78|uniprotkb:Q9UFW1|uniprotkb:Q9NWR3|uniprotkb:Q9P2B8|uniprotkb:Q9H9C9|uniprotkb:Q2M1N0|uniprotkb:Q7Z6C7|ensembl:ENSP00000297591	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:vir_human(display_long)|uniprotkb:VIRMA(gene name)|psi-mi:VIRMA(display_short)|uniprotkb:KIAA1429(gene name synonym)|uniprotkb:MSTP054(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_056311.2|refseq:NP_892121.1|ensembl:ENSG00000164944(gene)|ensembl:ENST00000297591(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0080009"(mRNA methylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026736|interpro:IPR031801|mint:Q69YN4	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:JXKhohRVBiT4P++8+/edtkir+h89606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q5JTZ9	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-308736|uniprotkb:Q8N198|uniprotkb:Q96D02|uniprotkb:Q9ULF0|uniprotkb:A2RRN5|ensembl:ENSP00000244571	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:syam_human(display_long)|uniprotkb:KIAA1270(gene name synonym)|uniprotkb:AARS2(gene name)|psi-mi:AARS2(display_short)|uniprotkb:AARSL(gene name synonym)|uniprotkb:Alanyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_065796.1|ensembl:ENSG00000124608(gene)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR012947(Threonyl/alanyl tRNA synthetase, SAD)|interpro:IPR018162|interpro:IPR018163|interpro:IPR018164|interpro:IPR018165|interpro:IPR023033|mint:Q5JTZ9|rcsb pdb:6NLQ|rcsb pdb:6NLY|rcsb pdb:6NOW|reactome:R-HSA-379726|ensembl:ENST00000244571(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004813"(alanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006400"(tRNA modification)|go:"GO:0006419"(alanyl-tRNA aminoacylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016597"(amino acid binding)|go:"GO:0070143"(mitochondrial alanyl-tRNA aminoacylation)|interpro:IPR002318(Alanyl-tRNA synthetase, class IIc)	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:RzNZMsaNjWpD4eB5AdgpjhC3vP09606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q5H9R7	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-355498|uniprotkb:Q3B7I1|uniprotkb:Q7L4R8|uniprotkb:Q8N3B2|uniprotkb:Q96MB2|uniprotkb:Q9H2K5|uniprotkb:Q9H2K6|uniprotkb:Q9HCL4|uniprotkb:Q9NUY3|uniprotkb:Q3I4Y0|uniprotkb:Q3KR35|uniprotkb:Q68CR3|intact:EBI-28971860|ensembl:ENSP00000377389	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:pp6r3_human(display_long)|uniprotkb:PPP6R3(gene name)|psi-mi:PPP6R3(display_short)|uniprotkb:C11orf23(gene name synonym)|uniprotkb:KIAA1558(gene name synonym)|uniprotkb:PP6R3(gene name synonym)|uniprotkb:SAPL(gene name synonym)|uniprotkb:Sporulation-induced transcript 4-associated protein SAPL(gene name synonym)|uniprotkb:SAPS domain family member 3(gene name synonym)|uniprotkb:SAPS3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001157632.1|refseq:NP_001157633.1|refseq:NP_001157634.1|refseq:NP_001157635.1|refseq:NP_001157636.1|refseq:NP_060782.2|ensembl:ENST00000265636|ensembl:ENSP00000265636|ensembl:ENSP00000377389|ensembl:ENST00000393801|ensembl:ENSP00000377390|ensembl:ENST00000524845|ensembl:ENSP00000431415|ensembl:ENST00000524904|ensembl:ENSP00000433058|ensembl:ENST00000529710|ensembl:ENSP00000437329|refseq:XP_011543442.1|refseq:XP_006718676.1|refseq:XP_006718677.1|refseq:XP_006718681.1|refseq:XP_006718687.1|refseq:XP_016873451.1|refseq:XP_016873452.1|refseq:XP_016873455.1|ensembl:ENSG00000110075(gene)|ensembl:ENST00000393800(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007587(SIT4 phosphatase-associated protein)|interpro:IPR016024(Armadillo-type fold)|mint:Q5H9R7|reactome:R-HSA-171319|reactome:R-HSA-204005	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:9hU14AmzYI9nORfchfMtLoyRecA9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q53EP0	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2847708|uniprotkb:Q6PIJ3|uniprotkb:B2RB36|uniprotkb:Q8NBU7|uniprotkb:Q6UXG1|uniprotkb:B3KXR8|uniprotkb:Q5U5T8|uniprotkb:Q9H5I7|uniprotkb:Q8IXB2|uniprotkb:Q9NSQ8|uniprotkb:Q96D78|uniprotkb:Q6UXZ5|uniprotkb:D3DNQ7|ensembl:ENSP00000338523|ensembl:ENSP00000389094|ensembl:ENSP00000411242	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:fnd3b_human(display_long)|uniprotkb:FNDC3B(gene name)|psi-mi:FNDC3B(display_short)|uniprotkb:FAD104(gene name synonym)|uniprotkb:NS5ABP37(gene name synonym)|uniprotkb:Factor for adipocyte differentiation 104(gene name synonym)|uniprotkb:HCV NS5A-binding protein 37(gene name synonym)|uniprotkb:UNQ2421/PRO4979/PRO34274(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001128567.1|refseq:NP_073600.3|ensembl:ENSP00000338523|ensembl:ENSP00000411242|ensembl:ENSP00000389094|ensembl:ENST00000421757|ensembl:ENSP00000408496|ensembl:ENST00000423424|ensembl:ENSP00000392471|ensembl:ENSG00000075420(gene)|ensembl:ENST00000336824(transcript)|ensembl:ENST00000415807(transcript)|ensembl:ENST00000416957(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0016021"(integral component of membrane)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|mint:Q53EP0	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:a8Yk/79adiuueOBYtKZSPnN71u09606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q4V328	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-717919|uniprotkb:A6NL78|uniprotkb:Q3MJ75|uniprotkb:Q4V327|uniprotkb:Q4V330|uniprotkb:Q5HYG1|uniprotkb:Q6N046|uniprotkb:Q96DH8|uniprotkb:Q9NQ43|uniprotkb:Q9ULQ3|ensembl:ENSP00000365606	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:grap1_human(display_long)|uniprotkb:GRIPAP1(gene name)|psi-mi:GRIPAP1(display_short)|uniprotkb:KIAA1167(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_064522.3|ensembl:ENSG00000068400(gene)|ensembl:ENST00000376423(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0072562"(blood microparticle)|go:"GO:0098837"(postsynaptic recycling endosome)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098998"(extrinsic component of postsynaptic early endosome membrane)|go:"GO:0099152"(regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0099158"(regulation of recycling endosome localization within postsynapse)|go:"GO:1905244"(regulation of modification of synaptic structure)|interpro:IPR026204|mint:Q4V328|dip:DIP-47299N	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:iIGfz5XvbexX4taRlMqWYsfAVBo9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q49A26	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2804292|ensembl:ENSP00000322716|uniprotkb:Q6P1Q2|uniprotkb:C9JJ40|uniprotkb:Q9BTI1|uniprotkb:Q9BXK2|uniprotkb:Q6V3W7|uniprotkb:C9JJ60|uniprotkb:B4DL47|uniprotkb:Q5U632	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:glyr1_human(display_long)|uniprotkb:HIBDL(gene name synonym)|uniprotkb:NP60(gene name synonym)|uniprotkb:3-hydroxyisobutyrate dehydrogenase-like protein(gene name synonym)|uniprotkb:Cytokine-like nuclear factor N-PAC(gene name synonym)|uniprotkb:Glyoxylate reductase 1 homolog(gene name synonym)|uniprotkb:Nuclear protein NP60(gene name synonym)|uniprotkb:Nuclear protein of 60 kDa(gene name synonym)|uniprotkb:GLYR1(gene name)|psi-mi:GLYR1(display_short)|uniprotkb:NDF(gene name synonym)|uniprotkb:Nucleosome-destabilizing factor(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSG00000140632(gene)|ensembl:ENST00000321919(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0042393"(histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050661"(NADP binding)|go:"GO:0051287"(NAD binding)|interpro:IPR000313(PWWP)|interpro:IPR006115(6-phosphogluconate dehydrogenase, NAD-binding)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR029154|interpro:IPR035501|interpro:IPR036291|mint:Q49A26|rcsb pdb:2UYY|rcsb pdb:4GUR|rcsb pdb:4GUS|rcsb pdb:4GUT|rcsb pdb:4GUU|rcsb pdb:4HSU|rcsb pdb:6R1U|rcsb pdb:6R25|refseq:XP_011521019.1|refseq:NP_001295025.1|refseq:NP_115958.2|refseq:NP_001311026.1	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:QsJhkB7Klk8D2R03vqPZzbi3f9g9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q2VWP7	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-12503569|ensembl:ENSP00000373937|uniprotkb:Q8N7D8	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:prtg_human(display_long)|uniprotkb:PRTG(gene name)|psi-mi:PRTG(display_short)|uniprotkb:Protein Shen-Dan(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSG00000166450(gene)|mint:Q2VWP7|ensembl:ENST00000389286(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0050768"(negative regulation of neurogenesis)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|refseq:NP_776175.2	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:BOC37mZ/S6SJUnCNslUTCorzQ5g9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q15637	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-744603|uniprotkb:Q14818|uniprotkb:Q14819|uniprotkb:Q15913|uniprotkb:Q8IY00|uniprotkb:Q92744|uniprotkb:Q92745|uniprotkb:Q969H7|uniprotkb:Q9BW01|uniprotkb:Q9UEI0|uniprotkb:B7Z1Q1|uniprotkb:C9JJE2|ensembl:ENSP00000366607	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:sf01_human(display_long)|uniprotkb:Zinc finger protein 162(gene name synonym)|uniprotkb:Transcription factor ZFM1(gene name synonym)|uniprotkb:Zinc finger gene in MEN1 locus(gene name synonym)|uniprotkb:Mammalian branch point-binding protein(gene name synonym)|uniprotkb:SF1(gene name)|psi-mi:SF1(display_short)|uniprotkb:ZFM1(gene name synonym)|uniprotkb:ZNF162(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001171501.1|refseq:NP_001171502.1|refseq:NP_004621.2|refseq:NP_973724.1|refseq:NP_973727.1|rcsb pdb:4FXX|rcsb pdb:4FXW|reactome:R-HSA-72163|refseq:XP_016873733.1|ensembl:ENSG00000168066(gene)|ensembl:ENST00000377390(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005840"(ribosome)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0030238"(male sex determination)|go:"GO:0030575"(nuclear body organization)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045131"(pre-mRNA branch point binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050810"(regulation of steroid biosynthetic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR031150|interpro:IPR032570|interpro:IPR036612|mint:Q15637|rcsb pdb:1K1G|rcsb pdb:1O0P|rcsb pdb:1OPI|rcsb pdb:2M09|rcsb pdb:2M0G|refseq:NP_001333292.1|refseq:NP_001333293.1|dip:DIP-29410N	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:N4k5Rvc5EDsSJt50J4ojje9p0249606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q15291	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-592823|uniprotkb:A8K272|uniprotkb:Q7Z6D8|uniprotkb:Q8NDZ7|ensembl:ENSP00000264515	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:rbbp5_human(display_long)|uniprotkb:Retinoblastoma-binding protein RBQ-3(gene name synonym)|uniprotkb:RBBP5(gene name)|psi-mi:RBBP5(display_short)|uniprotkb:RBQ3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001180201.1|refseq:NP_001180202.1|refseq:NP_005048.2|dip:DIP-29224N|ensembl:ENSG00000117222(gene)|ensembl:ENST00000264515(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037850|mint:Q15291|rcsb pdb:3P4F|rcsb pdb:4X8N|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6KM7|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6PWX|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:Zl8yHcbL1C6StHPyD+875Ccy6gk9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q15056	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-748492|uniprotkb:A8K3R1|uniprotkb:D3DXF6|uniprotkb:D3DXF8|ensembl:ENSP00000265753	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:if4h_human(display_long)|uniprotkb:Williams-Beuren syndrome chromosomal region 1 protein(gene name synonym)|uniprotkb:EIF4H(gene name)|psi-mi:EIF4H(display_short)|uniprotkb:WBSCR1(gene name synonym)|uniprotkb:KIAA0038(gene name synonym)|uniprotkb:WSCR1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_071496.1|refseq:NP_114381.1|ensembl:ENSG00000106682(gene)|ensembl:ENST00000265753(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0019953"(sexual reproduction)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034057"(RNA strand-exchange activity)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048589"(developmental growth)|go:"GO:0097010"(eukaryotic translation initiation factor 4F complex assembly)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034229|interpro:IPR035979|mint:Q15056|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:dNPoAzwFD5lFwCMnRl0cbXM3j8s9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q14563	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-26610586|ensembl:ENSP00000265362|ensembl:ENSP00000415260	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:sem3a_human(display_long)|uniprotkb:Semaphorin III(gene name synonym)|uniprotkb:SEMA3A(gene name)|psi-mi:SEMA3A(display_short)|uniprotkb:SEMAD(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSG00000075213(gene)|ensembl:ENST00000265362(transcript)|ensembl:ENST00000436949(transcript)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001764"(neuron migration)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007411"(axon guidance)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021637"(trigeminal nerve structural organization)|go:"GO:0021675"(nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0021828"(gonadotrophin-releasing hormone neuronal migration to the hypothalamus)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0036486"(ventral trunk neural crest cell migration)|go:"GO:0038191"(neuropilin binding)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0048846"(axon extension involved in axon guidance)|go:"GO:0048880"(sensory system development)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0060385"(axonogenesis involved in innervation)|go:"GO:0060666"(dichotomous subdivision of terminal units involved in salivary gland branching)|go:"GO:0061549"(sympathetic ganglion development)|go:"GO:0061551"(trigeminal ganglion development)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0097490"(sympathetic neuron projection extension)|go:"GO:0097491"(sympathetic neuron projection guidance)|go:"GO:0150020"(basal dendrite arborization)|go:"GO:1901166"(neural crest cell migration involved in autonomic nervous system development)|go:"GO:1902285"(semaphorin-plexin signaling pathway involved in neuron projection guidance)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|go:"GO:1903045"(neural crest cell migration involved in sympathetic nervous system development)|go:"GO:1903375"(facioacoustic ganglion development)|go:"GO:2000020"(positive regulation of male gonad development)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027231|interpro:IPR036179|interpro:IPR036352|interpro:IPR042820|mint:Q14563|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-399956|dip:DIP-5744N|refseq:NP_006071.1|refseq:XP_005250167.1|refseq:XP_005250168.1|refseq:XP_006715902.1|refseq:XP_011514036.1|refseq:XP_016867162.1	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:LrzZi1ccIRowKEYyzaG9pQco39E9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q14517	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1171918|ensembl:ENSP00000406229	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:fat1_human(display_long)|uniprotkb:CDHF7(gene name synonym)|uniprotkb:Cadherin-related tumor suppressor homolog(gene name synonym)|uniprotkb:Protein fat homolog(gene name synonym)|uniprotkb:FAT1(gene name)|psi-mi:FAT1(display_short)|uniprotkb:FAT(gene name synonym)|uniprotkb:Cadherin family member 7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_005236.2|refseq:XP_006714202.1|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002126(Cadherin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015919(Cadherin-like)|interpro:IPR018097|interpro:IPR020894|mint:Q14517|ensembl:ENSG00000083857(gene)|ensembl:ENST00000441802(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003412"(establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016324"(apical plasma membrane)	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:RFztJ1K2/XxuyQ5r603/zNsgNVM9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q14157	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-347762|uniprotkb:Q5VU75|uniprotkb:Q5VU76|uniprotkb:Q9BTU3|uniprotkb:Q9UGL2|uniprotkb:Q9UGL3|uniprotkb:Q9UGL5|uniprotkb:B4E0U8|uniprotkb:Q9UGL4|ensembl:ENSP00000355343|ensembl:ENSP00000389445	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:ubp2l_human(display_long)|uniprotkb:UBAP2L(gene name)|psi-mi:UBAP2L(display_short)|uniprotkb:Protein NICE-4(gene name synonym)|uniprotkb:KIAA0144(gene name synonym)|uniprotkb:NICE4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:XP_011508518.1|refseq:NP_001120792.1|refseq:NP_055662.3|refseq:NP_001274744.1|refseq:NP_001274745.1|refseq:XP_005245731.1|refseq:XP_016858467.1|refseq:XP_016858468.1|refseq:XP_016858475.1|refseq:XP_016858476.1|refseq:XP_016858478.1|refseq:XP_016858479.1|ensembl:ENSG00000143569(gene)|ensembl:ENST00000361546(transcript)|ensembl:ENST00000428931(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0031519"(PcG protein complex)|go:"GO:0034063"(stress granule assembly)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR022166|mint:Q14157	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:4iKY4hJOHGSyOOt8zfPhkeyth6Q9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q13442	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1390763|uniprotkb:Q92906|uniprotkb:D6W5S5|ensembl:ENSP00000222968	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:hap28_human(display_long)|uniprotkb:PDGF-associated protein(gene name synonym)|uniprotkb:PDGFA-associated protein 1(gene name synonym)|uniprotkb:PDAP1(gene name)|psi-mi:PDAP1(display_short)|uniprotkb:HASPP28(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_055706.1|ensembl:ENSG00000106244(gene)|ensembl:ENST00000350498(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR019380|interpro:IPR039876|mint:Q13442|reactome:R-HSA-6798695	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:8oY/0PM5kBr34vOdRXuGjIVFMgU9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q13155	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-745226|uniprotkb:Q75MR1|uniprotkb:Q96CZ5|uniprotkb:Q9P1L2|ensembl:ENSP00000223029|uniprotkb:F8W950	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:aimp2_human(display_long)|uniprotkb:Protein JTV-1(gene name synonym)|uniprotkb:AIMP2(gene name)|psi-mi:AIMP2(display_short)|uniprotkb:PRO0992(orf name)|uniprotkb:JTV1(gene name synonym)|uniprotkb:Multisynthase complex auxiliary component p38(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_006294.2|ensembl:ENSG00000106305(gene)|ensembl:ENST00000223029(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903632"(positive regulation of aminoacyl-tRNA ligase activity)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR031889|interpro:IPR036282|interpro:IPR041503|interpro:IPR042360|mint:Q13155|rcsb pdb:4DPG|rcsb pdb:4YCU|rcsb pdb:4YCW|rcsb pdb:5A1N|rcsb pdb:5A34|rcsb pdb:5A5H|rcsb pdb:5Y6L|rcsb pdb:6ILD|rcsb pdb:6IY6|rcsb pdb:6JPV|rcsb pdb:6K39|reactome:R-HSA-2408522|reactome:R-HSA-379716|dip:DIP-34421N|refseq:NP_001313536.1	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:VEBmJjo6t3dBY6mKpmUyVLamJFQ9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q12959	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-357481|ensembl:ENSP00000391732|ensembl:ENSP00000407531|ensembl:ENSP00000499437|uniprotkb:Q12958|uniprotkb:A5YKK7|uniprotkb:B7ZMM0|uniprotkb:B9EIQ5|uniprotkb:D3DXB8|uniprotkb:D3DXB9|uniprotkb:B4DGU1|uniprotkb:B4DGZ8|uniprotkb:E7EWL7|uniprotkb:E9PG21	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:dlg1_human(display_long)|uniprotkb:DLG1(gene name)|psi-mi:DLG1(display_short)|uniprotkb:Synapse-associated protein 97(gene name synonym)|uniprotkb:hDlg(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	reactome:R-HSA-9617324|reactome:R-HSA-9620244|ensembl:ENST00000419354(transcript)|ensembl:ENST00000448528(transcript)|ensembl:ENST00000670935(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002088"(lens development in camera-type eye)|ensembl:ENSG00000075711(gene)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0043113"(receptor clustering)|go:"GO:0043219"(lateral loop)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060022"(hard palate development)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1902473"(regulation of protein localization to synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903286"(regulation of potassium ion import)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903760"(regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903764"(regulation of potassium ion export across plasma membrane)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|refseq:NP_001091894.1|refseq:NP_001191315.1|refseq:NP_001191316.1|refseq:NP_001191317.1|refseq:NP_004078.2|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014704"(intercalated disc)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030432"(peristalsis)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031641"(regulation of myelination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0033268"(node of Ranvier)|go:"GO:0034629"|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043005"(neuron projection)|interpro:IPR019583|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:Q12959|rcsb pdb:1PDR|rcsb pdb:2M3M|rcsb pdb:2OQS|rcsb pdb:2X7Z|rcsb pdb:3LRA|rcsb pdb:3RL7|rcsb pdb:3RL8|rcsb pdb:3W9Y|rcsb pdb:4AMH|rcsb pdb:4G69|reactome:R-HSA-399719|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|reactome:R-HSA-438066|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|reactome:R-HSA-442982|reactome:R-HSA-447038|reactome:R-HSA-451308|reactome:R-HSA-5673001|reactome:R-HSA-8849932|reactome:R-HSA-9609736|refseq:XP_011510804.1|refseq:XP_011510807.1|refseq:XP_011510808.1|refseq:XP_005269346.1|refseq:NP_001277912.1|refseq:XP_016861289.1|refseq:XP_016861290.1|refseq:XP_016861291.1|refseq:XP_016861292.1|refseq:XP_016861294.1|refseq:XP_016861295.1|refseq:XP_016861296.1|refseq:XP_016861297.1|refseq:XP_016861298.1|refseq:XP_016861305.1|refseq:XP_016861306.1|refseq:XP_016861307.1|refseq:XP_016861308.1|refseq:XP_016861309.1|dip:DIP-33957N|refseq:XP_011510805.1|refseq:XP_016861299.1	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:ax5sUROdL8kF59RhocRWG6tUUkc9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q07666	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1364|uniprotkb:Q6PJX7|uniprotkb:Q8NB97|uniprotkb:Q99760|uniprotkb:D3DPP3|ensembl:ENSP00000313829	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:khdr1_human(display_long)|uniprotkb:SAM68(gene name synonym)|uniprotkb:Src-associated in mitosis 68 kDa protein(gene name synonym)|uniprotkb:KHDRBS1(gene name)|psi-mi:KHDRBS1(display_short)|uniprotkb:p21 Ras GTPase-activating protein-associated p62(gene name synonym)|uniprotkb:GAP-associated tyrosine phosphoprotein p62(gene name synonym)|uniprotkb:p68(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_006550.1|refseq:NP_001258807.1|dip:DIP-29007N|ensembl:ENSG00000121774(gene)|ensembl:ENST00000327300(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0046831"(regulation of RNA export from nucleus)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0070618"(Grb2-Sos complex)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|mint:Q07666|rcsb pdb:2XA6|rcsb pdb:3QHE|reactome:R-HSA-8849468	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:po7jC4Nxu+Aoz6T8K6VRWHp6MKQ9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q06481	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-79306|uniprotkb:Q13861|uniprotkb:Q14594|uniprotkb:Q14662|uniprotkb:Q71U10|uniprotkb:Q7M4L3|uniprotkb:Q9BT36|ensembl:ENSP00000263574|ensembl:ENSP00000497691|uniprotkb:B3KXX9|uniprotkb:H7BXI4	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:aplp2_human(display_long)|uniprotkb:APPH(gene name synonym)|uniprotkb:APPL2(gene name synonym)|uniprotkb:APLP2(gene name)|psi-mi:APLP2(display_short)|uniprotkb:Amyloid protein homolog(gene name synonym)|uniprotkb:CDEI box-binding protein(gene name synonym)|uniprotkb:"Amyloid beta (A4) precursor-like protein 2"(gene name synonym)|uniprotkb:Amyloid-like protein 2(gene name synonym)|uniprotkb:Sperm membrane protein YWK-II(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001135748.1|refseq:NP_001135749.1|refseq:NP_001135750.1|refseq:NP_001633.1|ensembl:ENSG00000084234(gene)|ensembl:ENST00000263574(transcript)|ensembl:ENST00000650012(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008201"(heparin binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031092"(platelet alpha granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002223(Proteinase inhibitor I2, Kunitz metazoa)|interpro:IPR008154(Amyloidogenic glycoprotein, extracellular)|interpro:IPR008155(Amyloidogenic glycoprotein, core)|interpro:IPR011178(Amyloidogenic glycoprotein, copper-binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015849(Amyloidogenic glycoprotein, heparin-binding)|interpro:IPR019543|interpro:IPR019744|interpro:IPR019745|interpro:IPR020901|interpro:IPR024329|interpro:IPR036176|interpro:IPR036454|interpro:IPR036669|interpro:IPR036880|mint:Q06481|rcsb pdb:5JBT|rcsb pdb:5TPT|reactome:R-HSA-114608|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:NP_001230228.1|dip:DIP-31047N	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:WBmrQxD6+MjRPRNHt63XDIs9++o9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q05195	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-8833637|uniprotkb:Q6FI41|uniprotkb:D6W5G2|uniprotkb:B2R6V8|uniprotkb:B7ZLI6|ensembl:ENSP00000264444	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:mad1_human(display_long)|uniprotkb:MAD(gene name synonym)|uniprotkb:Protein MAD(gene name synonym)|uniprotkb:MXD1(gene name)|psi-mi:MXD1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001189442.1|refseq:NP_001189443.1|refseq:NP_002348.1|dip:DIP-204N|ensembl:ENSG00000059728(gene)|ensembl:ENST00000264444(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR040157|mint:Q05195|rcsb pdb:1E91|rcsb pdb:1G1E|rcsb pdb:1NLW|rcsb pdb:1PD7|rcsb pdb:1S5Q	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:s9svBcYiX+lDX90aL1zzgy428Ao9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P78332	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2692323|uniprotkb:O75524|uniprotkb:O60549|uniprotkb:B4E0G6|uniprotkb:Q86SS3|ensembl:ENSP00000266022	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:rbm6_human(display_long)|uniprotkb:DEF3(gene name synonym)|uniprotkb:Lung cancer antigen NY-LU-12(gene name synonym)|uniprotkb:Protein G16(gene name synonym)|uniprotkb:RNA-binding motif protein 6(gene name synonym)|uniprotkb:RNA-binding protein DEF-3(gene name synonym)|uniprotkb:RBM6(gene name)|psi-mi:RBM6(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_005768.1|refseq:NP_001161054.1|refseq:XP_005264843.1|refseq:XP_005264844.1|ensembl:ENSG00000004534(gene)|ensembl:ENST00000266022(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006396"(RNA processing)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR028806|interpro:IPR034123|interpro:IPR034125|interpro:IPR035617|interpro:IPR035979|interpro:IPR041591|mint:P78332|refseq:XP_016860988.1|refseq:XP_016860989.1|refseq:XP_016860990.1|refseq:XP_016860991.1	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:qNU439nvkG+dQNbzNI+F2JI3B049606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P62081	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-354360|uniprotkb:Q6IPH1|uniprotkb:P23821|uniprotkb:P24818|uniprotkb:Q57Z92|ensembl:ENSP00000385018|ensembl:ENSP00000385286|ensembl:ENSP00000495273|ensembl:ENSP00000496654|ensembl:ENSP00000496757	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:rs7_human(display_long)|uniprotkb:RPS7(gene name)|psi-mi:RPS7(display_short)|uniprotkb:Small ribosomal subunit protein eS7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001002.1|ensembl:ENSG00000171863(gene)|ensembl:ENST00000403564(transcript)|ensembl:ENST00000406376(transcript)|ensembl:ENST00000462576(transcript)|ensembl:ENST00000645674(transcript)|ensembl:ENST00000646909(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030154"(cell differentiation)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0045202"(synapse)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050821"(protein stabilization)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000554(Ribosomal protein S7e)|mint:P62081|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6G4S	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:l4aG6I34lmzYhNapbdv2CAAwRwg9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P56199	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2554465|uniprotkb:B2RNU0|ensembl:ENSP00000282588	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:ita1_human(display_long)|uniprotkb:ITGA1(gene name)|psi-mi:ITGA1(display_short)|uniprotkb:Laminin and collagen receptor(gene name synonym)|uniprotkb:VLA-1(gene name synonym)|uniprotkb:CD49 antigen-like family member A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_852478.1|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042311"(vasodilation)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045123"(cellular extravasation)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098639"(collagen binding involved in cell-matrix adhesion)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|interpro:IPR036465|mint:P56199|rcsb pdb:1PT6|rcsb pdb:1QC5|rcsb pdb:1QCY|rcsb pdb:2L8S|rcsb pdb:2M32|rcsb pdb:4A0Q|rcsb pdb:5HGJ|reactome:R-HSA-216083|reactome:R-HSA-3000157|go:"GO:0034665"(integrin alpha1-beta1 complex)|reactome:R-HSA-416700|reactome:R-HSA-445355|reactome:R-HSA-447041|reactome:R-HSA-75892|ensembl:ENSG00000213949(gene)|ensembl:ENST00000282588(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008305"(integrin complex)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|dip:DIP-206N	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:rI8GnpuQlkN7TAnJ2eLpECEZOxs9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P52948	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-295727|uniprotkb:Q8IUT2|uniprotkb:Q8WYB0|uniprotkb:Q96E54|uniprotkb:Q9H3Q4|uniprotkb:Q9NT02|uniprotkb:Q9UF57|uniprotkb:Q9UHX0|uniprotkb:Q9Y6J4|uniprotkb:Q9Y6J5|ensembl:ENSP00000352091	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:nup98_human(display_long)|uniprotkb:NUP98(gene name)|psi-mi:NUP98(display_short)|uniprotkb:ADAR2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_005378.4|refseq:NP_057404.2|refseq:NP_624357.1|refseq:NP_624358.2|ensembl:ENST00000324932|ensembl:ENSP00000316032|ensembl:ENST00000355260|ensembl:ENSP00000347404|ensembl:ENSP00000352091|ensembl:ENST00000397004|ensembl:ENSP00000380199|ensembl:ENST00000397007|ensembl:ENSP00000380202|dip:DIP-32484N|ensembl:ENSG00000110713(gene)|ensembl:ENST00000359171(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005215"(transporter activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR021967|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|mint:P52948|rcsb pdb:1KO6|rcsb pdb:2Q5X|rcsb pdb:2Q5Y|rcsb pdb:3MMY|rcsb pdb:4OWR|rcsb pdb:5A9Q|rcsb pdb:6BZM|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:aW9NaKgLZti0wLEiVQogGukcWdE9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P51688	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2907521|ensembl:ENSP00000314606|uniprotkb:A8K5E2	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:sphm_human(display_long)|uniprotkb:SGSH(gene name)|psi-mi:SGSH(display_short)|uniprotkb:HSS(gene name synonym)|uniprotkb:Sulfoglucosamine sulfamidase(gene name synonym)|uniprotkb:Sulphamidase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSG00000181523(gene)|ensembl:ENST00000326317(transcript)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005764"(lysosome)|go:"GO:0006027"(glycosaminoglycan catabolic process)|go:"GO:0008449"(N-acetylglucosamine-6-sulfatase activity)|go:"GO:0016250"(N-sulfoglucosamine sulfohydrolase activity)|go:"GO:0030200"(heparan sulfate proteoglycan catabolic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0046872"(metal ion binding)|interpro:IPR000917(Sulphatase)|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR024607|interpro:IPR032506|mint:P51688|rcsb pdb:4MHX|rcsb pdb:4MIV|reactome:R-HSA-2024096|reactome:R-HSA-2206307|go:"GO:0070062"(extracellular exosome)|refseq:NP_000190.1	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:sd0wl3H/TL5kheDeJU6mHXLDiTM9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P49005	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-372354|ensembl:ENSP00000386105|ensembl:ENSP00000395231|ensembl:ENSP00000480186|uniprotkb:A4D2J4|uniprotkb:B2R5S4	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:dpod2_human(display_long)|uniprotkb:POLD2(gene name)|psi-mi:POLD2(display_short)|uniprotkb:DNA polymerase delta subunit p50(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001120690.1|ensembl:ENSG00000106628(gene)|ensembl:ENST00000406581(transcript)|ensembl:ENST00000452185(transcript)|ensembl:ENST00000610533(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0016035"(zeta DNA polymerase complex)|go:"GO:0042575"(DNA polymerase complex)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0071897"(DNA biosynthetic process)|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR024826|interpro:IPR040663|interpro:IPR041863|mint:P49005|rcsb pdb:3E0J|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|reactome:R-HSA-110314|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|refseq:NP_001243808.1|refseq:NP_006221.2	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:B8QUTohwg0iz3s5wdSdmcTGa28I9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P43243	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-352602|ensembl:ENSP00000378284|ensembl:ENSP00000482895|uniprotkb:Q9UHW0|uniprotkb:Q9UQ27|uniprotkb:D3DQC3|uniprotkb:B7ZAV5	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:matr3_human(display_long)|uniprotkb:KIAA0723(gene name synonym)|uniprotkb:MATR3(gene name)|psi-mi:MATR3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSG00000015479(gene)|ensembl:ENST00000394805(transcript)|ensembl:ENST00000618441(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003170"(heart valve development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034928|interpro:IPR034930|interpro:IPR035979|mint:P43243|refseq:NP_001181883.1|refseq:NP_001181884.1|refseq:NP_061322.2|refseq:NP_954659.1|refseq:NP_001181885.1|refseq:NP_001269207.1	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:3UZlyCZHgdr1SBgUctv9Ev7XBSQ9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P27707	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-715861|uniprotkb:Q5TZY7|uniprotkb:Q6FI11|uniprotkb:B2R8V6|ensembl:ENSP00000286648	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:dck_human(display_long)|uniprotkb:Deoxyadenosine kinase(gene name synonym)|uniprotkb:Deoxyguanosine kinase(gene name synonym)|uniprotkb:DCK(gene name)|psi-mi:DCK(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_000779.1|ensembl:ENSG00000156136(gene)|ensembl:ENST00000286648(transcript)|go:"GO:0004136"(deoxyadenosine kinase activity)|go:"GO:0004137"(deoxycytidine kinase activity)|go:"GO:0004138"(deoxyguanosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006220"(pyrimidine nucleotide metabolic process)|go:"GO:0008144"(obsolete drug binding)|go:"GO:0019136"(deoxynucleoside kinase activity)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR002624(Deoxynucleoside kinase)|interpro:IPR027417|interpro:IPR031314|mint:P27707|rcsb pdb:1P5Z|rcsb pdb:1P60|rcsb pdb:1P61|rcsb pdb:1P62|rcsb pdb:2A2Z|rcsb pdb:2A30|rcsb pdb:2A7Q|rcsb pdb:2NO0|rcsb pdb:2NO1|rcsb pdb:2NO6|rcsb pdb:2NO7|rcsb pdb:2NO9|rcsb pdb:2NOA|rcsb pdb:2QRN|rcsb pdb:2QRO|rcsb pdb:2ZI3|rcsb pdb:2ZI4|rcsb pdb:2ZI5|rcsb pdb:2ZI6|rcsb pdb:2ZI7|rcsb pdb:2ZI9|rcsb pdb:2ZIA|rcsb pdb:3HP1|rcsb pdb:3IPX|rcsb pdb:3IPY|rcsb pdb:3KFX|rcsb pdb:3MJR|rcsb pdb:3QEJ|rcsb pdb:3QEN|rcsb pdb:3QEO|rcsb pdb:4JLJ|rcsb pdb:4JLK|rcsb pdb:4JLM|rcsb pdb:4JLN|rcsb pdb:4KCG|rcsb pdb:4L5B|rcsb pdb:4Q18|rcsb pdb:4Q19|rcsb pdb:4Q1A|rcsb pdb:4Q1B|rcsb pdb:4Q1C|rcsb pdb:4Q1D|rcsb pdb:4Q1E|rcsb pdb:4Q1F|rcsb pdb:5MQJ|rcsb pdb:5MQL|rcsb pdb:5MQT|reactome:R-HSA-73614|reactome:R-HSA-74217	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:ikpxlOM4Z3EKULMzh9TTIqP/moc9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P25325	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2515082|ensembl:ENSP00000342333|ensembl:ENSP00000380402|ensembl:ENSP00000383950|ensembl:ENSP00000384812|uniprotkb:O75750|uniprotkb:A8MZ34|uniprotkb:B3KP52|uniprotkb:J3KPV7|uniprotkb:Q6FHN9	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:thtm_human(display_long)|uniprotkb:MPST(gene name)|psi-mi:MPST(display_short)|uniprotkb:TST2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	go:"GO:0070062"(extracellular exosome)|go:"GO:0070814"(hydrogen sulfide biosynthetic process)|interpro:IPR001307(Thiosulphate sulphurtransferase, conserved site)|interpro:IPR001763(Rhodanese-like)|interpro:IPR036873|mint:P25325|rcsb pdb:3OLH|rcsb pdb:4JGT|reactome:R-HSA-1614558|ensembl:ENSG00000128309(gene)|ensembl:ENST00000341116(transcript)|ensembl:ENST00000397225(transcript)|ensembl:ENST00000401419(transcript)|ensembl:ENST00000404802(transcript)|go:"GO:0000098"(sulfur amino acid catabolic process)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0004792"(thiosulfate sulfurtransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0009440"(cyanate catabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016784"(3-mercaptopyruvate sulfurtransferase activity)|go:"GO:0019346"(transsulfuration)|go:"GO:0021510"(spinal cord development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|refseq:NP_001013454.1|refseq:NP_001123989.1|refseq:NP_066949.2|refseq:XP_005261667.1|dip:DIP-613N	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:JDsHqxXe71bbWhgF2GcXCOspbpQ9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P21980	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-727668|uniprotkb:Q16436|uniprotkb:Q9BTN7|uniprotkb:Q9UH35|uniprotkb:Q6B838|uniprotkb:E1P5V9|ensembl:ENSP00000355330|uniprotkb:Q9H035	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:tgm2_human(display_long)|uniprotkb:TGM2(gene name)|psi-mi:TGM2(display_short)|uniprotkb:Tissue transglutaminase(gene name synonym)|uniprotkb:Transglutaminase C(gene name synonym)|uniprotkb:Transglutaminase-2(gene name synonym)|uniprotkb:Transglutaminase H(gene name synonym)|uniprotkb:Erythrocyte transglutaminase(gene name synonym)|uniprotkb:"Heart G alpha(h)"(gene name synonym)|uniprotkb:Isopeptidase TGM2(gene name synonym)|uniprotkb:"Protein G alpha(h)"(gene name synonym)|uniprotkb:Protein-glutamine deamidase TGM2(gene name synonym)|uniprotkb:Protein-glutamine dopaminyltransferase TGM2(gene name synonym)|uniprotkb:Protein-glutamine histaminyltransferase TGM2(gene name synonym)|uniprotkb:Protein-glutamine noradrenalinyltransferase TGM2(gene name synonym)|uniprotkb:Protein-glutamine serotonyltransferase TGM2(gene name synonym)|uniprotkb:Transglutaminase II(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_004604.2|refseq:NP_945189.1|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008233"(peptidase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0018153"("isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine")|go:"GO:0018277"(protein deamination)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031226"(intrinsic component of plasma membrane)|ensembl:ENSG00000198959(gene)|ensembl:ENST00000361475(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003810"(protein-glutamine gamma-glutamyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050568"(protein-glutamine glutaminase activity)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0060348"(bone development)|go:"GO:0060445"(branching involved in salivary gland morphogenesis)|go:"GO:0060662"(salivary gland cavitation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:0120295"(histone serotonyltransferase activity)|go:"GO:0120297"(histone dopaminyltransferase activity)|go:"GO:0120298"(peptide noradrenalinyltransferase activity)|go:"GO:0120299"(peptide histaminyltransferase activity)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904015"(cellular response to serotonin)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|interpro:IPR001102(Transglutaminase, N-terminal)|interpro:IPR002931(Transglutaminase-like)|interpro:IPR008958(Transglutaminase, C-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013808(Transglutaminase, conserved site)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR023608|interpro:IPR036238|interpro:IPR036985|interpro:IPR038765|mint:P21980|rcsb pdb:1FAU|rcsb pdb:1KV3|rcsb pdb:2Q3Z|rcsb pdb:3LY6|rcsb pdb:3S3J|rcsb pdb:3S3P|rcsb pdb:3S3S|rcsb pdb:4PYG|rcsb pdb:6A8P|rcsb pdb:6KZB|go:"GO:2000425"(regulation of apoptotic cell clearance)|refseq:XP_011527330.1|refseq:NP_001310245.1|dip:DIP-33557N	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:S61on+x/CwI9G/k/0UhS6pFO+wE9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P17858	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-487243|uniprotkb:Q96A64|uniprotkb:Q96IH4|uniprotkb:Q9BR91|ensembl:ENSP00000269848	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:pfkal_human(display_long)|uniprotkb:PFKL(gene name)|psi-mi:PFKL(display_short)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:Phosphofructo-1-kinase isozyme B(gene name synonym)|uniprotkb:6-phosphofructokinase type B(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001002021.2|refseq:NP_002617.3|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0009749"(response to glucose)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070095"(fructose-6-phosphate binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070061"(fructose binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000023(Phosphofructokinase)|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR022953|interpro:IPR035966|interpro:IPR041914|mint:P17858|reactome:R-HSA-6798695|reactome:R-HSA-70171|ensembl:ENSG00000141959(gene)|ensembl:ENST00000349048(transcript)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005945"(6-phosphofructokinase complex)	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:lP9/V5WcCl5rLpy4QEZnWkLCCcQ9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P11717	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1048580|uniprotkb:Q7Z7G9|uniprotkb:Q96PT5|ensembl:ENSP00000349437	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:mpri_human(display_long)|uniprotkb:Insulin-like growth factor 2 receptor(gene name synonym)|uniprotkb:Insulin-like growth factor II receptor(gene name synonym)|uniprotkb:M6P/IGF2 receptor(gene name synonym)|uniprotkb:300 kDa mannose 6-phosphate receptor(gene name synonym)|uniprotkb:IGF2R(gene name)|psi-mi:IGF2R(display_short)|uniprotkb:MPRI(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_000867.2|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0005010"(insulin-like growth factor-activated receptor activity)|go:"GO:0005520"(insulin-like growth factor binding)|go:"GO:0005537"(mannose binding)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|ensembl:ENSG00000197081(gene)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007165"(signal transduction)|ensembl:ENST00000356956(transcript)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0001889"(liver development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030118"(clathrin coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031995"(insulin-like growth factor II binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1905394"(retromer complex binding)|interpro:IPR000479(Cation-independent mannose-6-phosphate receptor)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|interpro:IPR044865|mint:P11717|rcsb pdb:1E6F|rcsb pdb:1GP0|rcsb pdb:1GP3|rcsb pdb:1GQB|rcsb pdb:1JPL|rcsb pdb:1JWG|rcsb pdb:1LF8|rcsb pdb:2CNJ|rcsb pdb:2L29|rcsb pdb:2L2A|rcsb pdb:2M68|rcsb pdb:2M6T|rcsb pdb:2V5N|rcsb pdb:2V5O|rcsb pdb:2V5P|rcsb pdb:5IEI|rcsb pdb:6N5X|rcsb pdb:6N5Y|rcsb pdb:6P8I|rcsb pdb:6V02|rcsb pdb:6Z30|rcsb pdb:6Z31|rcsb pdb:6Z32|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-6811440|reactome:R-HSA-8856825|reactome:R-HSA-8856828|dip:DIP-6027N	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:7lkG6WR8MQ/SONiTV/8g1ZTtKTU9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P11498	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2211322|uniprotkb:Q16705|uniprotkb:B4DN00|ensembl:ENSP00000377527|ensembl:ENSP00000377530|ensembl:ENSP00000377532|ensembl:ENSP00000435905|ensembl:ENSP00000498302|ensembl:ENSP00000498406|ensembl:ENSP00000498994	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:pyc_human(display_long)|uniprotkb:PC(gene name)|psi-mi:PC(display_short)|uniprotkb:Pyruvic carboxylase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:XP_011543388.1|refseq:XP_016873357.1|refseq:XP_016873358.1|refseq:XP_016873359.1|refseq:XP_016873360.1|refseq:XP_016873361.1|refseq:NP_000911.2|refseq:NP_001035806.1|refseq:NP_071504.2|refseq:XP_005274088.1|refseq:XP_005274089.1|refseq:XP_006718641.1|dip:DIP-46372N|ensembl:ENSG00000173599(gene)|ensembl:ENST00000393955(transcript)|ensembl:ENST00000393958(transcript)|ensembl:ENST00000393960(transcript)|ensembl:ENST00000529047(transcript)|ensembl:ENST00000651036(transcript)|ensembl:ENST00000651854(transcript)|ensembl:ENST00000652125(transcript)|go:"GO:0004736"(pyruvate carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0009374"(biotin binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0042802"(identical protein binding)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR001882(Biotin-binding site)|interpro:IPR003379(Conserved carboxylase region)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR005930(Pyruvate carboxylase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016185(PreATP-grasp-like fold)|mint:P11498|rcsb pdb:3BG3|rcsb pdb:3BG9|reactome:R-HSA-196780|reactome:R-HSA-3371599|reactome:R-HSA-70263	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:0xXv1wxe0AC1EO7wxSDVhBpHCUU9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P11387	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-876302|ensembl:ENSP00000354522|uniprotkb:Q15610|uniprotkb:Q5TFY3|uniprotkb:Q9UJN0|uniprotkb:O43256|uniprotkb:Q12855|uniprotkb:Q12856|uniprotkb:A8KA78|uniprotkb:E1P5W3	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:top1_human(display_long)|uniprotkb:DNA topoisomerase I(gene name synonym)|uniprotkb:TOP1(gene name)|psi-mi:TOP1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSG00000198900(gene)|ensembl:ENST00000361337(transcript)|go:"GO:0000932"(P-body)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006265"(DNA topological change)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007623"(circadian rhythm)|go:"GO:0012501"(programmed cell death)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032922"(circadian regulation of gene expression)|refseq:NP_003277.1|dip:DIP-36356N|go:"GO:0032993"(protein-DNA complex)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042493"|go:"GO:0043204"(perikaryon)|go:"GO:0097100"(supercoiled DNA binding)|interpro:IPR001631(DNA topoisomerase I, C-terminal)|interpro:IPR008336(DNA topoisomerase I, DNA binding, eukaryotic-type)|interpro:IPR011010(DNA breaking-rejoining enzyme, catalytic core)|interpro:IPR013030(DNA topoisomerase I, DNA binding, mixed alpha/beta motif, eukaryotic-type)|interpro:IPR013034(DNA topoisomerase I, DNA binding, alpha helical motif, eukaryotic-type)|interpro:IPR013499(DNA topoisomerase I, C-terminal, eukaryotic-type)|interpro:IPR013500(DNA topoisomerase I, catalytic core, eukaryotic-type)|interpro:IPR014711(DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type)|interpro:IPR014727(DNA topoisomerase I, catalytic core, alpha/beta subdomain, eukaryotic-type)|interpro:IPR018521|interpro:IPR025834|interpro:IPR036202|mint:P11387|rcsb pdb:1A31|rcsb pdb:1A35|rcsb pdb:1A36|rcsb pdb:1EJ9|rcsb pdb:1K4S|rcsb pdb:1K4T|rcsb pdb:1LPQ|rcsb pdb:1NH3|rcsb pdb:1R49|rcsb pdb:1RR8|rcsb pdb:1RRJ|rcsb pdb:1SC7|rcsb pdb:1SEU|rcsb pdb:1T8I|rcsb pdb:1TL8|reactome:R-HSA-4615885	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:kB+3PVybgNp2mtOmDa7x8sygFuU9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P11310	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-514381|uniprotkb:Q9NYF1|uniprotkb:Q5T4U4|ensembl:ENSP00000359878	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:acadm_human(display_long)|uniprotkb:Medium chain acyl-CoA dehydrogenase(gene name synonym)|uniprotkb:ACADM(gene name)|psi-mi:ACADM(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_000007.1|refseq:NP_001120800.1|dip:DIP-34281N|ensembl:ENSG00000117054(gene)|ensembl:ENST00000370841(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003995"(acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0009409"(response to cold)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019254"(carnitine metabolic process, CoA-linked)|go:"GO:0030424"(axon)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045329"(carnitine biosynthetic process)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0051793"(medium-chain fatty acid catabolic process)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR034180|interpro:IPR036250|interpro:IPR037069|mint:P11310|rcsb pdb:1EGC|rcsb pdb:1EGD|rcsb pdb:1EGE|rcsb pdb:1T9G|rcsb pdb:2A1T|rcsb pdb:4P13|reactome:R-HSA-1989781|reactome:R-HSA-77288|reactome:R-HSA-77346|reactome:R-HSA-77348	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:rfmTmYKNQr6R6ikvfYovZIctoz49606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P11279	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2805407|uniprotkb:B4DWL3|ensembl:ENSP00000333298|uniprotkb:Q9NP13|uniprotkb:Q8WU33|uniprotkb:Q9BRD2|uniprotkb:Q96I40	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:lamp1_human(display_long)|uniprotkb:CD107 antigen-like family member A(gene name synonym)|uniprotkb:LAMP1(gene name)|psi-mi:LAMP1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSG00000185896(gene)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031902"(late endosome membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043323"(positive regulation of natural killer cell degranulation)|go:"GO:0044754"(autolysosome)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0048102"(autophagic cell death)|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENST00000332556(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0061474"(phagolysosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072594"(establishment of protein localization to organelle)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:0097208"(alveolar lamellar body)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:0101004"(cytolytic granule membrane)|go:"GO:0140507"(granzyme-mediated programmed cell death signaling pathway)|go:"GO:1902513"(regulation of organelle transport along microtubule)|interpro:IPR002000("Lysosome-associated membrane glycoprotein (Lamp)/CD68")|interpro:IPR018134|mint:P11279|reactome:R-HSA-6798695|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010008"(endosome membrane)|refseq:NP_005552.3|dip:DIP-44670N	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:dP5MZG0I7/SM0EfCUhsESfQYvYU9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P07315	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-6875941|ensembl:ENSP00000282141|ensembl:ENSP00000496418|uniprotkb:Q53R50	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:crgc_human(display_long)|uniprotkb:CRYGC(gene name)|psi-mi:CRYGC(display_short)|uniprotkb:CRYG3(gene name synonym)|uniprotkb:Gamma-C-crystallin(gene name synonym)|uniprotkb:Gamma-crystallin 2-1(gene name synonym)|uniprotkb:Gamma-crystallin 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:XP_011508964.1|ensembl:ENSG00000163254(gene)|ensembl:ENSG00000285011(gene)|ensembl:ENST00000282141(transcript)|ensembl:ENST00000646204(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007601"(visual perception)|interpro:IPR001064(Beta and gamma crystallin)|interpro:IPR011024(Gamma-crystallin related)|mint:P07315|rcsb pdb:1LFE|rcsb pdb:2NBR|refseq:NP_066269.1	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:sTGY543Prp3u+F8JqIobyIUsYT09606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P06748	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-78579|uniprotkb:P08693|uniprotkb:Q12826|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q14115|uniprotkb:Q5EU94|uniprotkb:Q5EU95|uniprotkb:Q5EU96|uniprotkb:Q5EU97|uniprotkb:Q5EU98|uniprotkb:Q5EU99|uniprotkb:Q6V962|uniprotkb:Q8WTW5|uniprotkb:Q96AT6|uniprotkb:Q96DC4|uniprotkb:Q96EA5|uniprotkb:A8K3N7|uniprotkb:B5BU00|uniprotkb:Q9UDJ7|uniprotkb:D3DQL6|uniprotkb:Q9BYG9|ensembl:ENSP00000296930|ensembl:ENSP00000428755	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:npm_human(display_long)|uniprotkb:NPM1(gene name)|psi-mi:NPM1(display_short)|uniprotkb:NPM(gene name synonym)|uniprotkb:Nucleolar phosphoprotein B23(gene name synonym)|uniprotkb:Numatrin(gene name synonym)|uniprotkb:Nucleolar protein NO38(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_002511.1|refseq:NP_954654.1|refseq:NP_001032827.1|dip:DIP-30932N|ensembl:ENSG00000181163(gene)|ensembl:ENST00000296930(transcript)|ensembl:ENST00000517671(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001652"(granular component)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006407"(rRNA export from nucleus)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0010825"(positive regulation of centrosome duplication)|go:"GO:0010826"(negative regulation of centrosome duplication)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019843"(rRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032071"(regulation of endodeoxyribonuclease activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042255"(ribosome assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060699"(regulation of endoribonuclease activity)|go:"GO:0060735"(regulation of eIF2 alpha phosphorylation by dsRNA)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902629"(regulation of mRNA stability involved in cellular response to UV)|go:"GO:1902751"(positive regulation of cell cycle G2/M phase transition)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR032569|interpro:IPR036824|mint:P06748|rcsb pdb:2LLH|rcsb pdb:2P1B|rcsb pdb:2VXD|rcsb pdb:5EHD|reactome:R-HSA-180746|reactome:R-HSA-3899300|reactome:R-HSA-606279|reactome:R-HSA-6804115|reactome:R-HSA-8869496	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:HJ7Mg+XsIhuJiScPKiI0dIa6KpM9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P04040	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2432181|uniprotkb:A8K6C0|uniprotkb:B2RCZ9|uniprotkb:Q9UC85|uniprotkb:Q2M1U4|uniprotkb:Q4VXX5|uniprotkb:Q9BWT9|uniprotkb:D3DR07|ensembl:ENSP00000241052	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:cata_human(display_long)|uniprotkb:CAT(gene name)|psi-mi:CAT(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001743.1|ensembl:ENSG00000121691(gene)|ensembl:ENST00000241052(transcript)|go:"GO:0000268"(peroxisome targeting sequence binding)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004046"(aminoacylase activity)|go:"GO:0004096"(catalase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005764"(lysosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007568"(aging)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009060"(aerobic respiration)|go:"GO:0009642"(response to light intensity)|go:"GO:0009650"(UV protection)|go:"GO:0010193"(response to ozone)|go:"GO:0010288"(response to lead ion)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014823"(response to activity)|go:"GO:0014854"(response to inactivity)|go:"GO:0016020"(membrane)|go:"GO:0016209"(antioxidant activity)|go:"GO:0016684"(oxidoreductase activity, acting on peroxide as acceptor)|go:"GO:0019899"(enzyme binding)|go:"GO:0020027"(hemoglobin metabolic process)|go:"GO:0020037"(heme binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032355"(response to estradiol)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033189"(response to vitamin A)|go:"GO:0033197"(response to vitamin E)|go:"GO:0033591"(response to L-ascorbic acid)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045471"(response to ethanol)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0050661"(NADP binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0080184"(response to phenylpropanoid)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002226(Catalase)|interpro:IPR010582(Catalase-related)|interpro:IPR011614(Catalase, N-terminal)|interpro:IPR018028|interpro:IPR020835|interpro:IPR024708|interpro:IPR024711|interpro:IPR040333|mint:P04040|rcsb pdb:1DGB|rcsb pdb:1DGF|rcsb pdb:1DGG|rcsb pdb:1DGH|rcsb pdb:1F4J|rcsb pdb:1QQW|reactome:R-HSA-3299685|reactome:R-HSA-6798695|reactome:R-HSA-9033241|reactome:R-HSA-9615017	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:IWdPQIuCq9vCj8I0HmshkJwAAqg9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P02545	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-351935|uniprotkb:B4DI32|uniprotkb:E7EUI9|uniprotkb:P02546|uniprotkb:Q969I8|uniprotkb:Q96JA2|uniprotkb:D6RAQ3|uniprotkb:Q5I6Y4|uniprotkb:Q5I6Y6|uniprotkb:Q6UYC3|uniprotkb:Q5TCJ2|uniprotkb:Q5TCJ3|uniprotkb:D3DVB0|intact:EBI-28988787|ensembl:ENSP00000355292|ensembl:ENSP00000357283|ensembl:ENSP00000502256|ensembl:ENSP00000506771	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:lmna_human(display_long)|uniprotkb:LMNA(gene name)|psi-mi:LMNA(display_short)|uniprotkb:LMN1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_005563.1|refseq:NP_733821.1|refseq:NP_733822.1|refseq:NP_001244303.1|refseq:NP_001269553.1|refseq:NP_001269554.1|refseq:NP_001269555.1|ensembl:ENSG00000160789(gene)|ensembl:ENST00000361308(transcript)|ensembl:ENST00000368300(transcript)|ensembl:ENST00000675939(transcript)|ensembl:ENST00000683032(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005638"(lamin filament)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007517"(muscle organ development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072201"(negative regulation of mesenchymal cell proliferation)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:P02545|rcsb pdb:1IFR|rcsb pdb:1IVT|rcsb pdb:1X8Y|rcsb pdb:2XV5|rcsb pdb:2YPT|rcsb pdb:3GEF|rcsb pdb:3V4Q|rcsb pdb:3V4W|rcsb pdb:3V5B|rcsb pdb:6GHD|rcsb pdb:6JLB|rcsb pdb:6RPR|rcsb pdb:6SNZ|rcsb pdb:6YF5|rcsb pdb:6YJD|reactome:R-HSA-1221632|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-381038|reactome:R-HSA-4419969|reactome:R-HSA-6802952|reactome:R-HSA-8862803|ensembl:ENSP00000503633|ensembl:ENST00000682650|ensembl:ENSP00000506904|ensembl:ENST00000677389|ensembl:ENSP00000506771|ensembl:ENSP00000355292|ensembl:ENST00000368299|ensembl:ENSP00000357282|ensembl:ENSP00000357283|ensembl:ENST00000368301|ensembl:ENSP00000357284|ensembl:ENST00000448611|ensembl:ENSP00000395597|ensembl:ENST00000473598|ensembl:ENSP00000421821|ensembl:ENSP00000502256|ensembl:ENST00000676385|ensembl:ENSP00000502091|dip:DIP-32948N|dip:DIP-58162N	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:OS/QDFLGOD2PElQ6mCpBtk6xh/09606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P02511	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-739060|uniprotkb:O43416|uniprotkb:B0YIX0|uniprotkb:Q9UC37|uniprotkb:Q9UC38|uniprotkb:Q9UC39|uniprotkb:Q9UC40|uniprotkb:Q9UC41|ensembl:ENSP00000227251|ensembl:ENSP00000433560|ensembl:ENSP00000434247|ensembl:ENSP00000435931|ensembl:ENSP00000436051|ensembl:ENSP00000436089|ensembl:ENSP00000437149|ensembl:ENSP00000483554|ensembl:ENSP00000498735|ensembl:ENSP00000499082	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:cryab_human(display_long)|uniprotkb:CRYAB(gene name)|psi-mi:CRYAB(display_short)|uniprotkb:CRYA2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-27(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:Rosenthal fiber component(gene name synonym)|uniprotkb:Heat shock protein beta-5(gene name synonym)|uniprotkb:HSPB5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSG00000109846(gene)|ensembl:ENST00000227251(transcript)|ensembl:ENST00000526180(transcript)|ensembl:ENST00000527899(transcript)|ensembl:ENST00000527950(transcript)|ensembl:ENST00000531198(transcript)|ensembl:ENST00000533475(transcript)|ensembl:ENST00000533879(transcript)|ensembl:ENST00000616970(transcript)|ensembl:ENST00000650687(transcript)|ensembl:ENST00000651164(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006936"(muscle contraction)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P02511|rcsb pdb:2KLR|rcsb pdb:2N0K|rcsb pdb:2WJ7|rcsb pdb:2Y1Y|rcsb pdb:2Y1Z|rcsb pdb:2YGD|rcsb pdb:3J07|rcsb pdb:2Y22|rcsb pdb:3L1G|rcsb pdb:3SGM|rcsb pdb:3SGN|rcsb pdb:3SGO|rcsb pdb:3SGP|rcsb pdb:3SGR|rcsb pdb:3SGS|rcsb pdb:4M5S|rcsb pdb:4M5T|rcsb pdb:5VVV|rcsb pdb:6BP9|reactome:R-HSA-3371571|refseq:NP_001876.1|refseq:XP_011540910.1|refseq:NP_001276736.1|refseq:NP_001276737.1|dip:DIP-35017N	-	-	crc64:AE08BED46B7849CB	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:495Z42oQhkAUdADrAEOKIC5oICo9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P02489	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-6875961|ensembl:ENSP00000291554|intact:EBI-25838900|uniprotkb:A0A140G945|uniprotkb:E9PHE4|uniprotkb:Q53X53	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:cryaa_human(display_long)|uniprotkb:CRYAA(gene name)|psi-mi:CRYAA(display_short)|uniprotkb:CRYA1(gene name synonym)|uniprotkb:HSPB4(gene name synonym)|uniprotkb:Heat shock protein beta-4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001300979.1|ensembl:ENSG00000160202(gene)|ensembl:ENST00000291554(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050896"(response to stimulus)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR012274(Alpha-crystallin, subunit A)|mint:P02489|rcsb pdb:6T1R|refseq:NP_000385.1|dip:DIP-41265N	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:+d2016YcOZzaZpV57L9crFbTzEA9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:O95819	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2511133|intact:EBI-28985706|ensembl:ENSP00000314363|uniprotkb:Q9NST7|uniprotkb:O75172|uniprotkb:E7ESS2	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:m4k4_human(display_long)|uniprotkb:MAP4K4(gene name)|psi-mi:MAP4K4(display_short)|uniprotkb:HGK(gene name synonym)|uniprotkb:KIAA0687(gene name synonym)|uniprotkb:NIK(gene name synonym)|uniprotkb:MAPK/ERK kinase kinase kinase 4(gene name synonym)|uniprotkb:HPK/GCK-like kinase HGK(gene name synonym)|uniprotkb:Nck-interacting kinase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_663719.2|ensembl:ENST00000347699(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008017"(microtubule binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032014"(positive regulation of ARF protein signal transduction)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0061179"(negative regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0070571"(negative regulation of neuron projection regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001180(Citron-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:O95819|rcsb pdb:4OBO|rcsb pdb:4OBP|rcsb pdb:4OBQ|rcsb pdb:4RVT|rcsb pdb:4U3Y|rcsb pdb:4U3Z|rcsb pdb:4U40|rcsb pdb:4U41|rcsb pdb:4U42|rcsb pdb:4U43|rcsb pdb:4U44|rcsb pdb:4U45|rcsb pdb:4ZK5|rcsb pdb:4ZP5|rcsb pdb:5DI1|rcsb pdb:5J95|rcsb pdb:5W5Q|reactome:R-HSA-2559580|ensembl:ENSG00000071054(gene)|refseq:NP_001229488.1|refseq:NP_004825.3|refseq:NP_663720.1|ensembl:ENSP00000314363|ensembl:ENST00000350878|ensembl:ENSP00000343658|ensembl:ENST00000634702|ensembl:ENSP00000489579	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:wEXGp6vM4HhwldyeQJKvEdilMpQ9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:O95394	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-9515816|uniprotkb:B2RB65|uniprotkb:B4DX94|uniprotkb:D6RF12|uniprotkb:E1P547|uniprotkb:E9PF86|uniprotkb:Q5JWR4|uniprotkb:Q96J46|uniprotkb:Q9H8G5|uniprotkb:Q9NS94|uniprotkb:Q9NTT6|uniprotkb:Q9UFV5|uniprotkb:Q9UIY2|ensembl:ENSP00000424874	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:agm1_human(display_long)|uniprotkb:PGM3(gene name)|psi-mi:PGM3(display_short)|uniprotkb:AGM1(gene name synonym)|uniprotkb:Acetylglucosamine phosphomutase(gene name synonym)|uniprotkb:N-acetylglucosamine-phosphate mutase(gene name synonym)|uniprotkb:Phosphoglucomutase-3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:XP_016866425.1|refseq:NP_001186846.1|refseq:NP_001186848.1|refseq:NP_056414.1|ensembl:ENSG00000013375(gene)|ensembl:ENST00000513973(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004610"(phosphoacetylglucosamine mutase activity)|go:"GO:0004614"(phosphoglucomutase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006041"(glucosamine metabolic process)|go:"GO:0006048"(UDP-N-acetylglucosamine biosynthetic process)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019255"(glucose 1-phosphate metabolic process)|go:"GO:0030097"(hemopoiesis)|interpro:IPR005843(Alpha-D-phosphohexomutase, C-terminal)|interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|interpro:IPR016066(Alpha-D-phosphohexomutase, conserved site)|interpro:IPR016657(Phosphoacetylglucosamine mutase)|interpro:IPR036900|mint:O95394|reactome:R-HSA-446210	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:W5By9C2GhzNKHCyrO1opg79FQ6I9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:O95159	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-718439|uniprotkb:O14616|uniprotkb:Q9UID0|uniprotkb:A8K7E9|ensembl:ENSP00000294258	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:zfpl1_human(display_long)|uniprotkb:Zinc finger protein MCG4(gene name synonym)|uniprotkb:ZFPL1(gene name)|psi-mi:ZFPL1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_006773.2|ensembl:ENSG00000162300(gene)|ensembl:ENST00000294258(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR039043|mint:O95159	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:8U/G+YcD/pF1Cg44ghFOW+D8tD89606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:O76062	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2115348|uniprotkb:O95982|uniprotkb:Q8IY06|uniprotkb:Q96E64|uniprotkb:Q96GZ1|uniprotkb:A8K4H0|ensembl:ENSP00000279263	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:erg24_human(display_long)|uniprotkb:TM7SF2(gene name)|psi-mi:TM7SF2(display_short)|uniprotkb:ANG1(gene name synonym)|uniprotkb:C-14 sterol reductase(gene name synonym)|uniprotkb:Sterol C14-reductase(gene name synonym)|uniprotkb:Transmembrane 7 superfamily member 2(gene name synonym)|uniprotkb:Another new gene 1 protein(gene name synonym)|uniprotkb:Putative sterol reductase SR-1(gene name synonym)|uniprotkb:"3-beta-hydroxysterol Delta (14)-reductase"(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_003264.2|refseq:NP_001264162.1|ensembl:ENSG00000149809(gene)|ensembl:ENST00000279263(transcript)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016627"(oxidoreductase activity, acting on the CH-CH group of donors)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0050613"(delta14-sterol reductase activity)|go:"GO:0050661"(NADP binding)|interpro:IPR001171(ERG4/ERG24 ergosterol biosynthesis protein)|interpro:IPR018083|mint:O76062|reactome:R-HSA-191273|reactome:R-HSA-2426168	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:jLbMB63WqPnGYB7Q3zzTd76G/sg9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:O75096	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-310873|uniprotkb:B2RN39|uniprotkb:Q4AC85|uniprotkb:Q5KTZ5|ensembl:ENSP00000367888	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:lrp4_human(display_long)|uniprotkb:LRP4(gene name)|psi-mi:LRP4(display_short)|uniprotkb:KIAA0816(gene name synonym)|uniprotkb:MEGF7(gene name synonym)|uniprotkb:Multiple epidermal growth factor-like domains 7(gene name synonym)|uniprotkb:LRP10(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_002325.2|ensembl:ENSG00000134569(gene)|ensembl:ENST00000378623(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0001942"(hair follicle development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0009986"(cell surface)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030425"(dendrite)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0060173"(limb development)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097104"(postsynaptic membrane assembly)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0150094"(amyloid-beta clearance by cellular catabolic process)|go:"GO:1901631"(positive regulation of presynaptic membrane organization)|go:"GO:1904395"(positive regulation of skeletal muscle acetylcholine-gated channel clustering)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018097|interpro:IPR023415|interpro:IPR026823|interpro:IPR036055|mint:O75096|reactome:R-HSA-3000178	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:IbVlpu46vNtRqtZvYsySZ6go3kE9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:O75027	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1236950|uniprotkb:O75345|uniprotkb:Q5VWY7|uniprotkb:Q5VWY8|uniprotkb:Q9BRE1|uniprotkb:Q9UND1|uniprotkb:Q9UP01|uniprotkb:G3XAC4|ensembl:ENSP00000362492	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:abcb7_human(display_long)|uniprotkb:ABCB7(gene name)|psi-mi:ABCB7(display_short)|uniprotkb:ABC7(gene name synonym)|uniprotkb:ATP-binding cassette transporter 7(gene name synonym)|uniprotkb:ATP-binding cassette sub-family B member 7, mitochondrial(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001258626.1|ensembl:ENSG00000131269(gene)|ensembl:ENST00000373394(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0015232"(heme transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0055085"(transmembrane transport)|go:"GO:0070455"(positive regulation of heme biosynthetic process)|go:"GO:0140466"(iron-sulfur cluster export from the mitochondrion)|go:"GO:0140481"(ABC-type iron-sulfur cluster transporter activity)|go:"GO:1903331"(positive regulation of iron-sulfur cluster assembly)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|interpro:IPR039421|mint:O75027|reactome:R-HSA-1369007|reactome:R-HSA-2564830|refseq:NP_004290.2|refseq:NP_001258625.1	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:nsOzSS/enZTkOfd1nRlk8Wv4KRM9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:O43681	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2515857|ensembl:ENSP00000349887|ensembl:ENSP00000466379|uniprotkb:Q53FC6|uniprotkb:A8K740|uniprotkb:A6NHP8|uniprotkb:Q92849|intact:EBI-2818109	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:get3_human(display_long)|uniprotkb:GET3(gene name)|psi-mi:GET3(display_short)|uniprotkb:ARSA(gene name synonym)|uniprotkb:ASNA1(gene name synonym)|uniprotkb:Arsenical pump-driving ATPase(gene name synonym)|uniprotkb:Arsenite-stimulated ATPase(gene name synonym)|uniprotkb:Guided entry of tail-anchored proteins factor 3, ATPase(gene name synonym)|uniprotkb:TRC40(gene name synonym)|uniprotkb:Transmembrane domain recognition complex 40 kDa ATPase subunit(gene name synonym)|uniprotkb:hARSA-I(gene name synonym)|uniprotkb:hASNA-I(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSG00000198356(gene)|ensembl:ENST00000357332(transcript)|ensembl:ENST00000591090(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0015105"(arsenite transmembrane transporter activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043529"(GET complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|interpro:IPR016300(Arsenite-transporting ATPase)|interpro:IPR025723|interpro:IPR027417|interpro:IPR027542|mint:O43681|rcsb pdb:6SO5|reactome:R-HSA-9609523|refseq:NP_004308.2	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:j2jKZb3MH8Bd3hnoQhDO6bjbyxI9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:O43395	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-744322|uniprotkb:O43446|uniprotkb:Q5VT54|uniprotkb:B4DSY9|intact:EBI-28983618|ensembl:ENSP00000315379	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:prpf3_human(display_long)|uniprotkb:Pre-mRNA-splicing factor 3(gene name synonym)|uniprotkb:U4/U6 snRNP 90 kDa protein(gene name synonym)|uniprotkb:PRPF3(gene name)|psi-mi:PRPF3(display_short)|uniprotkb:HPRP3(gene name synonym)|uniprotkb:PRP3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_004689.1|ensembl:ENSP00000315379|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|interpro:IPR002483(Splicing factor PWI)|interpro:IPR010541(Protein of unknown function DUF1115)|interpro:IPR013881(Pre-mRNA-splicing factor 3)|interpro:IPR027104|interpro:IPR036483|mint:O43395|rcsb pdb:1X4Q|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163|ensembl:ENSG00000117360(gene)|ensembl:ENST00000324862(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|dip:DIP-34508N	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:Y2aO1gQjTU8JERVtrLpgbXq7nLU9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:O15229	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-26560980|uniprotkb:A2A2U8|uniprotkb:A2A2U9|uniprotkb:A2A2V0|uniprotkb:Q5SY07|uniprotkb:Q5SY08|uniprotkb:Q5SY09|ensembl:ENSP00000355517	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:kmo_human(display_long)|uniprotkb:KMO(gene name)|psi-mi:KMO(display_short)|uniprotkb:Kynurenine 3-hydroxylase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_003670.2|ensembl:ENSG00000117009(gene)|ensembl:ENST00000366559(transcript)|go:"GO:0004502"(kynurenine 3-monooxygenase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006569"(tryptophan catabolic process)|go:"GO:0007568"(aging)|go:"GO:0009651"(response to salt stress)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0019674"(NAD metabolic process)|go:"GO:0019805"(quinolinate biosynthetic process)|go:"GO:0034276"(kynurenic acid biosynthetic process)|go:"GO:0034354"('de novo' NAD biosynthetic process from tryptophan)|go:"GO:0043420"(anthranilate metabolic process)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0070189"(kynurenine metabolic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071949"(FAD binding)|go:"GO:0097052"(L-kynurenine metabolic process)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903296"(positive regulation of glutamate secretion, neurotransmission)|interpro:IPR002938(Monooxygenase, FAD-binding)|interpro:IPR027545|interpro:IPR036188|mint:O15229|rcsb pdb:5X68|reactome:R-HSA-71240	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:e1IhGFgSdNxde/jDHi9pg79O6jc9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:O15084	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-359567|uniprotkb:Q6ULS0|uniprotkb:Q6ZT57|uniprotkb:B4DES5|uniprotkb:Q1WWL4|uniprotkb:Q29RW6|uniprotkb:Q3B857|ensembl:ENSP00000382379|ensembl:ENSP00000397341	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:anr28_human(display_long)|uniprotkb:ANKRD28(gene name)|psi-mi:ANKRD28(display_short)|uniprotkb:KIAA0379(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 28(gene name synonym)|uniprotkb:Phosphatase interactor targeting protein hnRNP K(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001182027.1|refseq:NP_001182028.1|refseq:NP_056014.2|refseq:XP_011531842.1|refseq:XP_005265053.1|refseq:XP_016861515.1|refseq:XP_016861516.1|dip:DIP-27583N|ensembl:ENSG00000206560(gene)|ensembl:ENST00000399451(transcript)|ensembl:ENST00000412318(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:O15084|reactome:R-HSA-171319|reactome:R-HSA-204005	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:YLJtZR7PWrGejJ8EFI093KRtb2Q9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:O00567	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-396034|uniprotkb:Q2M3T6|uniprotkb:Q9NQ05|ensembl:ENSP00000370589	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:nop56_human(display_long)|uniprotkb:NOP56(gene name)|psi-mi:NOP56(display_short)|uniprotkb:NOL5A(gene name synonym)|uniprotkb:Nucleolar protein 5A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_006383.2|ensembl:ENSG00000101361(gene)|ensembl:ENST00000329276(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070761"(pre-snoRNP complex)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|mint:O00567|reactome:R-HSA-390471|reactome:R-HSA-6790901|reactome:R-HSA-6791226	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:nXIsxj5Spl+kflK0yGJFykVylmA9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:O00468	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-947482|uniprotkb:Q5SVA2|uniprotkb:Q60FE1|uniprotkb:Q7KYS8|uniprotkb:Q8N4J5|uniprotkb:Q96IC1|uniprotkb:Q9BTD4|uniprotkb:Q5SVA1	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:agrin_human(display_long)|uniprotkb:AGRN(gene name)|psi-mi:AGRN(display_short)|uniprotkb:AGRIN(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610537|imex:IM-28698-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_940978.2|interpro:IPR004850(Agrin NtA)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR003645(Follistatin-like, N-terminal)|interpro:IPR001791(Laminin G)|interpro:IPR002350(Proteinase inhibitor I1, Kazal)|interpro:IPR000082(SEA)|interpro:IPR008993(TIMP-like, OB-fold)|refseq:XP_005244806.1|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003884(Factor I membrane attack complex)|mint:O00468|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033691"(sialic acid binding)|go:"GO:0035374"(chondroitin sulfate binding)|go:"GO:0043113"(receptor clustering)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043236"(laminin binding)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045162"(clustering of voltage-gated sodium channels)|go:"GO:0045202"(synapse)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050808"(synapse organization)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|reactome:R-HSA-1971475|reactome:R-HSA-2022928|reactome:R-HSA-2024096|reactome:R-HSA-216083|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-3560783|reactome:R-HSA-3560801|reactome:R-HSA-3656237|reactome:R-HSA-3656253|reactome:R-HSA-419037|reactome:R-HSA-4420332|reactome:R-HSA-975634|interpro:IPR036058|interpro:IPR036364|refseq:NP_001292204.1	-	-	-	figure legend:fig. 3a suppl.table 2|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:LRk4v4aYLk5kep9EIbjjiCGM7OM9606	rigid:AQBS3Rha2JlM+wbJ391rV54nz/8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q99996	uniprotkb:Q9NRI5	intact:EBI-1048311|uniprotkb:O14869|uniprotkb:O43355|uniprotkb:O94895|uniprotkb:Q75N20|uniprotkb:Q9UQH3|uniprotkb:Q9UQQ4|uniprotkb:Q9Y6B8|uniprotkb:A4D1F0|uniprotkb:Q9Y6Y2|uniprotkb:A4D1F2|uniprotkb:A4D1F4|ensembl:ENSP00000348573	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	psi-mi:akap9_human(display_long)|uniprotkb:Protein kinase A-anchoring protein 9(gene name synonym)|uniprotkb:A-kinase anchor protein 450 kDa(gene name synonym)|uniprotkb:A-kinase anchor protein 350 kDa(gene name synonym)|uniprotkb:AKAP 120-like protein(gene name synonym)|uniprotkb:Protein hyperion(gene name synonym)|uniprotkb:Protein yotiao(gene name synonym)|uniprotkb:Centrosome- and Golgi-localized PKN-associated protein(gene name synonym)|uniprotkb:AKAP9(gene name)|psi-mi:AKAP9(display_short)|uniprotkb:AKAP350(gene name synonym)|uniprotkb:AKAP450(gene name synonym)|uniprotkb:KIAA0803(gene name synonym)	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610825|imex:IM-28698-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005742.4|refseq:NP_671714.1|ensembl:ENSG00000127914(gene)|ensembl:ENST00000356239(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007165"(signal transduction)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034629"|go:"GO:0034705"(potassium channel complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044307"(dendritic branch)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR005539(ELK)|interpro:IPR019528|interpro:IPR028745|mint:Q99996|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5576890|reactome:R-HSA-5576893|reactome:R-HSA-5620912|reactome:R-HSA-6802952|reactome:R-HSA-8854518|ensembl:ENSP00000348573|ensembl:ENST00000680766|ensembl:ENSP00000505204|dip:DIP-29942N	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	-	-	-	figure legend:fig.3b|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:LQUNbTHUgEsjayFEZvczC4e90Nw9606	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rigid:QweXnT3hxK6E75NDDfBPOvuq/fU	false	-	flag tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5SW79	uniprotkb:Q9NRI5	intact:EBI-1104799|uniprotkb:O75058|uniprotkb:Q5SW77|uniprotkb:Q5SW78|uniprotkb:Q7LGA9|uniprotkb:Q86W31|uniprotkb:Q9UQ08|uniprotkb:Q9UQ09|intact:EBI-2559293|intact:EBI-2554822|ensembl:ENSP00000355500|ensembl:ENSP00000483344	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	psi-mi:ce170_human(display_long)|uniprotkb:CEP170(gene name)|psi-mi:CEP170(display_short)|uniprotkb:FAM68A(gene name synonym)|uniprotkb:KAB(gene name synonym)|uniprotkb:KIAA0470(gene name synonym)|uniprotkb:KARP-1-binding protein(gene name synonym)	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610831|imex:IM-28698-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035863.1|refseq:NP_001035864.1|refseq:NP_055627.2|ensembl:ENSG00000143702(gene)|ensembl:ENSG00000276725(gene)|ensembl:ENST00000366542(transcript)|ensembl:ENST00000612450(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0072686"(mitotic spindle)|go:"GO:0120103"(centriolar subdistal appendage)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR026644|interpro:IPR029300|mint:Q5SW79|rcsb pdb:4JON|refseq:XP_016858425.1|dip:DIP-37594N	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	-	-	-	figure legend:fig.3b|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:gEJsUZqeO9zpm94iMzIAUvsUbqc9606	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rigid:wKrKDZplQ2QijxDQXSPtcNwZh4U	false	-	flag tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5VU43	uniprotkb:Q9NRI5	intact:EBI-1105124|uniprotkb:A2RU15|uniprotkb:O75042|uniprotkb:O75065|uniprotkb:Q5VU42|uniprotkb:Q5VU44|uniprotkb:Q5VU45|uniprotkb:Q5VU46|uniprotkb:Q5VU47|uniprotkb:Q5VU48|uniprotkb:Q5VU49|uniprotkb:Q68DU2|uniprotkb:Q6AZ93|uniprotkb:Q6PK88|uniprotkb:Q86T40|uniprotkb:Q86TB2|uniprotkb:Q8N3W0|uniprotkb:Q8TAY9|uniprotkb:Q9HCP2|uniprotkb:Q9HCP3|uniprotkb:Q9HCP4|uniprotkb:Q9HCP5|uniprotkb:Q2YDC1|uniprotkb:A0A0A0MRM0|ensembl:ENSP00000358360|intact:EBI-11953012|intact:EBI-11051716|uniprotkb:A0A0C4DFQ0|uniprotkb:E9PL24	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	psi-mi:myome_human(display_long)|uniprotkb:PDE4DIP(gene name)|psi-mi:PDE4DIP(display_short)|uniprotkb:CMYA2(gene name synonym)|uniprotkb:KIAA0454(gene name synonym)|uniprotkb:KIAA0477(gene name synonym)|uniprotkb:MMGL(gene name synonym)|uniprotkb:Phosphodiesterase 4D-interacting protein(gene name synonym)|uniprotkb:Cardiomyopathy-associated protein 2(gene name synonym)	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610837|imex:IM-28698-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000178104(gene)|ensembl:ENST00000313431|ensembl:ENSP00000316434|ensembl:ENST00000369347|ensembl:ENSP00000358353|ensembl:ENST00000369349|ensembl:ENSP00000358355|ensembl:ENST00000369351|ensembl:ENSP00000358357|ensembl:ENSP00000358360|ensembl:ENST00000369356|ensembl:ENSP00000358363|ensembl:ENST00000529945|ensembl:ENSP00000433392|ensembl:ENST00000530472|ensembl:ENSP00000482121|ensembl:ENST00000618462|ensembl:ENSP00000479409|ensembl:ENST00000369354(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0019899"(enzyme binding)|go:"GO:0030016"(myofibril)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0034622"|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR010630(Protein of unknown function DUF1220)|interpro:IPR012943(Spindle associated)|mint:Q5VU43|refseq:NP_001002810.1|refseq:NP_001182189.1|refseq:NP_001182190.1|refseq:NP_071754.3|refseq:NP_001002811.2|refseq:NP_001002812.2|refseq:NP_001185761.2|refseq:NP_001185763.3|refseq:NP_055459.5|refseq:XP_016855361.1|refseq:XP_016855362.1|refseq:XP_016858514.1|refseq:XP_016858515.1|dip:DIP-51263N	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	-	-	-	figure legend:fig.3b|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:eDnkSq7sbpRyz2lqqLvKDzKXHfQ9606	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rigid:Fp1oMcn3pA7DZonTTmCaATZRGEg	false	-	flag tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9UKE5	uniprotkb:Q9NRI5	intact:EBI-1051794|intact:EBI-1762540|uniprotkb:O60298|uniprotkb:Q8WUY7|uniprotkb:Q9UKD8|uniprotkb:Q9UKD9|uniprotkb:Q9UKE0|uniprotkb:Q9UKE1|uniprotkb:Q9UKE2|uniprotkb:Q9UKE3|uniprotkb:Q9UKE4|intact:EBI-1968916|uniprotkb:A8K4U1|uniprotkb:D3DNQ6|uniprotkb:A7E2A3|ensembl:ENSP00000399511	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	psi-mi:tnik_human(display_long)|uniprotkb:TNIK(gene name)|psi-mi:TNIK(display_short)|uniprotkb:KIAA0551(gene name synonym)	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610843|imex:IM-28698-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001155032.1|refseq:NP_001155033.1|refseq:NP_001155034.1|refseq:NP_001155035.1|refseq:NP_001155036.1|refseq:NP_001155037.1|refseq:NP_001155038.1|refseq:NP_055843.1|dip:DIP-37562N|ensembl:ENSG00000154310(gene)|ensembl:ENST00000436636(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007256"(obsolete activation of JNKK activity)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001180(Citron-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q9UKE5|rcsb pdb:2X7F|rcsb pdb:5AX9|rcsb pdb:5CWZ|rcsb pdb:5D7A|rcsb pdb:6RA5|rcsb pdb:6RA7|reactome:R-HSA-2559580	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	-	-	-	figure legend:fig.3b|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:b+FNQZpz2ZX+wcVH9wuqOgZQ/cE9606	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rigid:L7I1dFU4oNka1+lVJtni1RtIb1Q	false	-	flag tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P46060	uniprotkb:Q9NRI5	intact:EBI-396091|uniprotkb:Q96JJ2|ensembl:ENSP00000401470|ensembl:ENSP00000348577|ensembl:ENSP00000385866	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	psi-mi:ragp1_human(display_long)|uniprotkb:RANGAP1(gene name)|psi-mi:RANGAP1(display_short)|uniprotkb:KIAA1835(gene name synonym)|uniprotkb:SD(gene name synonym)	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610849|imex:IM-28698-41	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002874.1|ensembl:ENST00000356244(transcript)|ensembl:ENST00000405486(transcript)|ensembl:ENST00000455915(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0016235"(aggresome)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:XP_011528596.1|refseq:XP_011528597.1|refseq:NP_001304859.1|go:"GO:0031965"(nuclear membrane)|interpro:IPR009109(Ran-GTPase activating protein 1, C-terminal)|interpro:IPR032675|interpro:IPR036720|mint:P46060|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2IO2|rcsb pdb:2IO3|rcsb pdb:2IY0|rcsb pdb:3UIN|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:5D2M|reactome:R-HSA-141444|reactome:R-HSA-165054|reactome:R-HSA-2467813|interpro:IPR001611(Leucine-rich repeat)|reactome:R-HSA-2500257|reactome:R-HSA-3108232|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0045296"(cadherin binding)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048678"(response to axon injury)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1904117"(cellular response to vasopressin)|go:"GO:1990723"(cytoplasmic periphery of the nuclear pore complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|ensembl:ENSG00000100401(gene)|refseq:XP_006724352.1|reactome:R-HSA-4615885|refseq:NP_001265580.1|reactome:R-HSA-68877|reactome:R-HSA-9615933|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_016884382.1|refseq:XP_016884383.1|refseq:XP_016884384.1|refseq:XP_016884385.1|refseq:XP_016884386.1|dip:DIP-29079N	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	-	-	-	figure legend:fig.3b|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:pUpd+7p5CeAKaRGLo/bXTeiwjiM9606	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rigid:kdvrufw30Q6EXDIgnZRA7No+jaQ	false	-	flag tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8TEM1	uniprotkb:Q9NRI5	intact:EBI-372826|uniprotkb:A6NN56|uniprotkb:O94980|uniprotkb:Q6NXG6|uniprotkb:Q8NBJ1|uniprotkb:Q9H6C8|uniprotkb:Q9UFP3|ensembl:ENSP00000254508	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	psi-mi:po210_human(display_long)|uniprotkb:KIAA0906(gene name synonym)|uniprotkb:NUP210(gene name)|psi-mi:NUP210(display_short)|uniprotkb:PSEC0245(orf name)|uniprotkb:Nuclear envelope pore membrane protein POM 210(gene name synonym)|uniprotkb:Pore membrane protein of 210 kDa(gene name synonym)|uniprotkb:Nucleoporin Nup210(gene name synonym)	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610857|imex:IM-28698-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-HSA-9610379|refseq:NP_079199.2|ensembl:ENSG00000132182(gene)|ensembl:ENST00000254508(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR003343(Bacterial Ig-like, group 2)|interpro:IPR008964(Invasin/intimin cell-adhesion)|mint:Q8TEM1|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	-	-	-	figure legend:fig.3b|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:udIemFThWYk0VC21Ml4EDDQWXlg9606	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rigid:IFL4j4iBLUZFvmSC335OJ6oyXZk	false	-	flag tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O95819	uniprotkb:Q9NRI5	intact:EBI-2511133|intact:EBI-28985706|ensembl:ENSP00000314363|uniprotkb:Q9NST7|uniprotkb:O75172|uniprotkb:E7ESS2	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	psi-mi:m4k4_human(display_long)|uniprotkb:MAP4K4(gene name)|psi-mi:MAP4K4(display_short)|uniprotkb:HGK(gene name synonym)|uniprotkb:KIAA0687(gene name synonym)|uniprotkb:NIK(gene name synonym)|uniprotkb:MAPK/ERK kinase kinase kinase 4(gene name synonym)|uniprotkb:HPK/GCK-like kinase HGK(gene name synonym)|uniprotkb:Nck-interacting kinase(gene name synonym)	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610865|imex:IM-28698-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_663719.2|ensembl:ENST00000347699(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008017"(microtubule binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032014"(positive regulation of ARF protein signal transduction)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0061179"(negative regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0070571"(negative regulation of neuron projection regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001180(Citron-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:O95819|rcsb pdb:4OBO|rcsb pdb:4OBP|rcsb pdb:4OBQ|rcsb pdb:4RVT|rcsb pdb:4U3Y|rcsb pdb:4U3Z|rcsb pdb:4U40|rcsb pdb:4U41|rcsb pdb:4U42|rcsb pdb:4U43|rcsb pdb:4U44|rcsb pdb:4U45|rcsb pdb:4ZK5|rcsb pdb:4ZP5|rcsb pdb:5DI1|rcsb pdb:5J95|rcsb pdb:5W5Q|reactome:R-HSA-2559580|ensembl:ENSG00000071054(gene)|refseq:NP_001229488.1|refseq:NP_004825.3|refseq:NP_663720.1|ensembl:ENSP00000314363|ensembl:ENST00000350878|ensembl:ENSP00000343658|ensembl:ENST00000634702|ensembl:ENSP00000489579	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	-	-	-	figure legend:fig.3b|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:wEXGp6vM4HhwldyeQJKvEdilMpQ9606	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rigid:4WbWWlpf0Mgn7S+lUMBvEVc/qVI	false	-	flag tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q4V328	uniprotkb:Q9NRI5	intact:EBI-717919|uniprotkb:A6NL78|uniprotkb:Q3MJ75|uniprotkb:Q4V327|uniprotkb:Q4V330|uniprotkb:Q5HYG1|uniprotkb:Q6N046|uniprotkb:Q96DH8|uniprotkb:Q9NQ43|uniprotkb:Q9ULQ3|ensembl:ENSP00000365606	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	psi-mi:grap1_human(display_long)|uniprotkb:GRIPAP1(gene name)|psi-mi:GRIPAP1(display_short)|uniprotkb:KIAA1167(gene name synonym)	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610871|imex:IM-28698-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064522.3|ensembl:ENSG00000068400(gene)|ensembl:ENST00000376423(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0072562"(blood microparticle)|go:"GO:0098837"(postsynaptic recycling endosome)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098998"(extrinsic component of postsynaptic early endosome membrane)|go:"GO:0099152"(regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0099158"(regulation of recycling endosome localization within postsynapse)|go:"GO:1905244"(regulation of modification of synaptic structure)|interpro:IPR026204|mint:Q4V328|dip:DIP-47299N	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	-	-	-	figure legend:fig.3b|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606("human-neuronal_precursor_cells(stem cells)")|taxid:9606(Human Neuronal Precursor Cells/neural stem progenitor cells)	-	2021/01/18	2021/02/01	rogid:iIGfz5XvbexX4taRlMqWYsfAVBo9606	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rigid:abXSfUbe3yla765mc4Mg6+kT4UQ	false	-	flag tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NRI5	uniprotkb:O95071	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-358329|uniprotkb:O94970|uniprotkb:Q9NPL3|ensembl:ENSP00000429084|uniprotkb:B2RP24|intact:EBI-10967451|uniprotkb:J3KMW7	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:ubr5_human(display_long)|uniprotkb:UBR5(gene name)|psi-mi:UBR5(display_short)|uniprotkb:HYD(gene name synonym)|uniprotkb:KIAA0896(gene name synonym)|uniprotkb:EDD(gene name synonym)|uniprotkb:EDD1(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase, HECT domain-containing 1(gene name synonym)|uniprotkb:Hyperplastic discs protein homolog(gene name synonym)|uniprotkb:Progestin-induced protein(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase UBR5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001269802.1|ensembl:ENST00000520539(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|ensembl:ENSG00000104517(gene)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR000569(HECT)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR024725|interpro:IPR035983|interpro:IPR036053|mint:O95071|rcsb pdb:1I2T|rcsb pdb:2QHO|refseq:NP_056986.2|rcsb pdb:3PT3|dip:DIP-32930N	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:5yiXAYJbV4iA8d3btwaVfL7vaik9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P67936	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1642100|uniprotkb:P07226|uniprotkb:Q15659|uniprotkb:Q9BU85|uniprotkb:Q9H8Q3|uniprotkb:Q5U0D9|uniprotkb:Q9UCS1|uniprotkb:Q9UCS2|uniprotkb:Q9UCS3|uniprotkb:Q9UCS4|ensembl:ENSP00000495347	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:tpm4_human(display_long)|uniprotkb:TPM4(gene name)|psi-mi:TPM4(display_short)|uniprotkb:Tropomyosin-4(gene name synonym)|uniprotkb:TM30p1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001138632.1|refseq:NP_003281.1|ensembl:ENSG00000167460(gene)|ensembl:ENST00000643579(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001725"(stress fiber)|go:"GO:0002102"(podosome)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016020"(membrane)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000533(Tropomyosin)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|mint:P67936|reactome:R-HSA-390522|reactome:R-HSA-445355|reactome:R-HSA-9013424	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:o8bLltMHW3vvC7Tp6YpiC0M6lkw9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P06753	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-355607|uniprotkb:P12324|uniprotkb:Q969Q2|uniprotkb:Q9NQH8|uniprotkb:Q5VU71|uniprotkb:Q2QD06|uniprotkb:D3DV71|ensembl:ENSP00000498577|intact:EBI-11063811|uniprotkb:Q5VU66|uniprotkb:Q5VU72|intact:EBI-4289841|uniprotkb:Q5VU58|uniprotkb:Q5VU63|uniprotkb:Q8TCG3	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:tpm3_human(display_long)|uniprotkb:TPM3(gene name)|psi-mi:TPM3(display_short)|uniprotkb:Tropomyosin-3(gene name synonym)|uniprotkb:Gamma-tropomyosin(gene name synonym)|uniprotkb:Tropomyosin-5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001265120.1|refseq:NP_001036816.1|refseq:NP_001036817.1|refseq:NP_689476.2|refseq:NP_705935.1|ensembl:ENSG00000143549(gene)|ensembl:ENST00000651641(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000533(Tropomyosin)|mint:P06753|rcsb pdb:6OTN|reactome:R-HSA-390522|reactome:R-HSA-445355|reactome:R-HSA-9013424|refseq:NP_001036818.1|refseq:NP_001265118.1	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:vHELhEyfZxpK8zHMEveODiYBZmM9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q01082	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-351561|intact:EBI-1642531|uniprotkb:O60837|uniprotkb:Q16057|uniprotkb:Q53R99|uniprotkb:Q59ER3|uniprotkb:Q8IX99|uniprotkb:B2RP63|ensembl:ENSP00000349259	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:sptb2_human(display_long)|uniprotkb:SPTBN1(gene name)|psi-mi:SPTBN1(display_short)|uniprotkb:SPTB2(gene name synonym)|uniprotkb:Spectrin, non-erythroid beta chain 1(gene name synonym)|uniprotkb:Beta-II spectrin(gene name synonym)|uniprotkb:Fodrin beta chain(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_003119.2|refseq:NP_842565.2|ensembl:ENSG00000115306(gene)|ensembl:ENST00000356805(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008091"(spectrin)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030673"(axolemma)|go:"GO:0031430"(M band)|go:"GO:0032437"(cuticular plate)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071709"(membrane assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|interpro:IPR041681|mint:Q01082|rcsb pdb:1AA2|rcsb pdb:1BKR|rcsb pdb:3EDV|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6807878|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9703465|reactome:R-HSA-373753|refseq:XP_005264574.1|refseq:XP_006712150.1|refseq:XP_016860268.1|refseq:XP_016860269.1|refseq:XP_016860270.1|dip:DIP-33182N	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:rQJxsoEirg87umLjsEwHcQ0/blQ9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P60660	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-300817|uniprotkb:P16475|uniprotkb:P24572|uniprotkb:P24573|uniprotkb:Q12790|ensembl:ENSP00000446955|ensembl:ENSP00000448101|uniprotkb:Q6IAZ0|uniprotkb:Q6IPY5|uniprotkb:Q561V9	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:myl6_human(display_long)|uniprotkb:MYL6(gene name)|psi-mi:MYL6(display_short)|uniprotkb:Smooth muscle and nonmuscle myosin light chain alkali 6(gene name synonym)|uniprotkb:Myosin light chain alkali 3(gene name synonym)|uniprotkb:Myosin light chain 3(gene name synonym)|uniprotkb:17 kDa myosin light chain(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSG00000092841(gene)|ensembl:ENST00000548293(transcript)|ensembl:ENST00000550697(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0006936"(muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016020"(membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0031982"(vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|mint:P60660|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|refseq:NP_066299.2|refseq:NP_524147.2	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:LhE3NUqcuHlOla13C0vjnFZfzy89606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P21333	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-350432|uniprotkb:Q8NF52|intact:EBI-1103234|ensembl:ENSP00000358866|uniprotkb:Q5HY53|uniprotkb:Q5HY55|uniprotkb:E9KL45	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:flna_human(display_long)|uniprotkb:FLNA(gene name)|psi-mi:FLNA(display_short)|uniprotkb:FLN(gene name synonym)|uniprotkb:FLN1(gene name synonym)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	go:"GO:0007195"(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:"GO:1902396"(protein localization to bicellular tight junction)|refseq:NP_001104026.1|refseq:NP_001447.2|ensembl:ENSG00000196924(gene)|ensembl:ENST00000369850(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097368"(establishment of Sertoli cell barrier)|go:"GO:0097440"(apical dendrite)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:0046332"(SMAD binding)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0019900"(kinase binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031523"(Myb complex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045296"(cadherin binding)|reactome:R-HSA-114608|reactome:R-HSA-430116|reactome:R-HSA-446353|reactome:R-HSA-5627123|reactome:R-HSA-8983711|rcsb pdb:6EW1|go:"GO:1905031"(regulation of membrane repolarization during cardiac muscle cell action potential)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:P21333|rcsb pdb:2AAV|rcsb pdb:2BP3|rcsb pdb:2BRQ|rcsb pdb:2J3S|rcsb pdb:2JF1|rcsb pdb:2K3T|rcsb pdb:2K7P|rcsb pdb:2K7Q|rcsb pdb:2MTP|rcsb pdb:2W0P|rcsb pdb:2WFN|rcsb pdb:3CNK|rcsb pdb:3HOC|rcsb pdb:3HOP|rcsb pdb:3HOR|rcsb pdb:3ISW|rcsb pdb:3RGH|rcsb pdb:4M9P|rcsb pdb:4P3W|rcsb pdb:5XR1|rcsb pdb:6D8C|go:"GO:1905000"(regulation of membrane repolarization during atrial cardiac muscle cell action potential)|dip:DIP-1136N	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:ZxGK5OSMy8cNsyt7Ax2KXb8bn9M9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q16643	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-351394|uniprotkb:Q9UFZ5|uniprotkb:B2RBG0|ensembl:ENSP00000308532|intact:EBI-4404710|uniprotkb:A8MV58	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:dreb_human(display_long)|uniprotkb:DBN1(gene name)|psi-mi:DBN1(display_short)|uniprotkb:Developmentally-regulated brain protein(gene name synonym)|uniprotkb:D0S117E(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_004386.2|refseq:NP_543157.1|refseq:XP_005265884.1|ensembl:ENSG00000113758(gene)|ensembl:ENST00000309007(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005921"(gap junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0010643"(cell communication by chemical coupling)|go:"GO:0010644"(cell communication by electrical coupling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0042641"(actomyosin)|go:"GO:0030425"(dendrite)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0051015"(actin filament binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1902685"(positive regulation of receptor localization to synapse)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR028438|interpro:IPR029006|mint:Q16643|go:"GO:0030426"(growth cone)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031915"(positive regulation of synaptic plasticity)|rcsb pdb:5Y1Z|rcsb pdb:5ZZ9|reactome:R-HSA-9013405|reactome:R-HSA-9013407|reactome:R-HSA-9013418|reactome:R-HSA-9013422|go:"GO:0032507"(maintenance of protein location in cell)|refseq:XP_016864629.1	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:0+VPJM5mTuG2jzmzGG3iLswmCUc9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P47756	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-353595|uniprotkb:Q5U0L4|uniprotkb:Q8TB49|uniprotkb:Q9NUC4|uniprotkb:Q32Q68|ensembl:ENSP00000364284|ensembl:ENSP00000501528	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:capzb_human(display_long)|uniprotkb:CAPZB(gene name)|psi-mi:CAPZB(display_short)|uniprotkb:CapZ beta(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001193469.1|refseq:NP_004921.1|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051490"(negative regulation of filopodium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071203"(WASH complex)|go:"GO:0097224"(sperm connecting piece)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|interpro:IPR001698(F-actin capping protein, beta subunit)|interpro:IPR019771|interpro:IPR037282|interpro:IPR042276|interpro:IPR043175|mint:P47756|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-9013405|reactome:R-HSA-9035034|reactome:R-HSA-9662360|reactome:R-HSA-983231|ensembl:ENSG00000077549(gene)|ensembl:ENST00000375142(transcript)|ensembl:ENST00000674432(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005903"(brush border)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030863"(cortical cytoskeleton)|refseq:NP_001269091.1	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:qRXsrB2fLT1DMVIVRWKFYe4Aln49606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P07355	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8|ensembl:ENSP00000379342|ensembl:ENSP00000387545|ensembl:ENSP00000411352|ensembl:ENSP00000452858|ensembl:ENSP00000452895|ensembl:ENSP00000452981|ensembl:ENSP00000453694|ensembl:ENSP00000453859|ensembl:ENSP00000503447|ensembl:ENSP00000503757|ensembl:ENSP00000503855|ensembl:ENSP00000504035|ensembl:ENSP00000504164	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|refseq:XP_016877579.1|refseq:XP_016877580.1|ensembl:ENSG00000182718(gene)|ensembl:ENST00000396024(transcript)|ensembl:ENST00000421017(transcript)|ensembl:ENST00000451270(transcript)|ensembl:ENST00000557906(transcript)|ensembl:ENST00000558558(transcript)|ensembl:ENST00000559818(transcript)|ensembl:ENST00000559956(transcript)|ensembl:ENST00000560468(transcript)|ensembl:ENST00000677968(transcript)|ensembl:ENST00000678061(transcript)|ensembl:ENST00000678450(transcript)|ensembl:ENST00000678870(transcript)|ensembl:ENST00000679109(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0005509"(calcium ion binding)|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|go:"GO:0097066"(response to thyroid hormone)	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P68032	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-352273|uniprotkb:P04270|ensembl:ENSP00000290378	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:actc_human(display_long)|uniprotkb:ACTC1(gene name)|psi-mi:ACTC1(display_short)|uniprotkb:ACTC(gene name synonym)|uniprotkb:Alpha-cardiac actin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_005150.1|ensembl:ENSG00000159251(gene)|ensembl:ENST00000290378(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031674"(I band)|go:"GO:0033275"(actin-myosin filament sliding)|go:"GO:0042493"|go:"GO:0044297"(cell body)|go:"GO:0045471"(response to ethanol)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68032|reactome:R-HSA-390522|reactome:R-HSA-8980692|reactome:R-HSA-9013026	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:U/lKYqWUWMSC3fBHFaAcgzfk+3w9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P12814	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-351710|uniprotkb:Q9BTN1|uniprotkb:Q1HE25|uniprotkb:B7TY16|intact:EBI-3866221|uniprotkb:B3V8S3|uniprotkb:B4DHH3|ensembl:ENSP00000193403	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:actn1_human(display_long)|uniprotkb:ACTN1(gene name)|psi-mi:ACTN1(display_short)|uniprotkb:Alpha-actinin cytoskeletal isoform(gene name synonym)|uniprotkb:Non-muscle alpha-actinin-1(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001093.1|refseq:NP_001123477.1|refseq:NP_001123476.1|dip:DIP-33184N|ensembl:ENSG00000072110(gene)|ensembl:ENST00000193403(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0017166"(vinculin binding)|go:"GO:0030018"(Z disc)|go:"GO:0030220"(platelet formation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0036344"(platelet morphogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0051639"(actin filament network formation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099186"(structural constituent of postsynapse)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:P12814|rcsb pdb:2EYI|rcsb pdb:2EYN|rcsb pdb:2N8Y|rcsb pdb:2N8Z|reactome:R-HSA-114608|reactome:R-HSA-3000170|reactome:R-HSA-373753|reactome:R-HSA-446388|reactome:R-HSA-9013405|reactome:R-HSA-9013418|reactome:R-HSA-9035034	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:guTURyt26f1ort4NAlYyabNc+WE9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:O60506	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1024357|uniprotkb:Q53H05|uniprotkb:Q5TCG2|uniprotkb:Q8IW78|uniprotkb:Q8N599|uniprotkb:Q96LC1|uniprotkb:Q96LC2|uniprotkb:Q9Y583|uniprotkb:Q5TCG3|uniprotkb:E1P501|uniprotkb:E1P502|ensembl:ENSP00000358635|ensembl:ENSP00000503783|ensembl:ENSP00000504706	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:hnrpq_human(display_long)|uniprotkb:Synaptotagmin-binding, cytoplasmic RNA-interacting protein(gene name synonym)|uniprotkb:Glycine- and tyrosine-rich RNA-binding protein(gene name synonym)|uniprotkb:NS1-associated protein 1(gene name synonym)|uniprotkb:SYNCRIP(gene name)|psi-mi:SYNCRIP(display_short)|uniprotkb:HNRPQ(gene name synonym)|uniprotkb:NSAP1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001153145.1|refseq:NP_001153146.1|refseq:NP_001153147.1|refseq:NP_001240700.1|refseq:NP_001153148.1|refseq:NP_001153149.1|refseq:NP_006363.4|ensembl:ENSG00000135316(gene)|ensembl:ENST00000369622(transcript)|ensembl:ENST00000676688(transcript)|ensembl:ENST00000678355(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034544|interpro:IPR034548|interpro:IPR035979|interpro:IPR041337|mint:O60506|rcsb pdb:2DGU|rcsb pdb:2MXT|rcsb pdb:2NBB|rcsb pdb:6KOR|refseq:XP_016865667.1|refseq:XP_005248694.1|dip:DIP-35540N	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:2rDkXIp/wWzTOoVtN7Bd3uqZo689606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P62244	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-347895|ensembl:ENSP00000318646|ensembl:ENSP00000457000|ensembl:ENSP00000458115|ensembl:ENSP00000458528|uniprotkb:P39027|uniprotkb:P39031|uniprotkb:Q3MHD9|uniprotkb:Q8C023|uniprotkb:Q9BV24	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:rs15a_human(display_long)|uniprotkb:RPS15A(gene name)|psi-mi:RPS15A(display_short)|uniprotkb:Small ribosomal subunit protein uS8(gene name synonym)|uniprotkb:OK/SW-cl.82(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSG00000134419(gene)|ensembl:ENST00000322989(transcript)|ensembl:ENST00000563390(transcript)|ensembl:ENST00000565420(transcript)|ensembl:ENST00000572008(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045787"(positive regulation of cell cycle)|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|go:"GO:0070062"(extracellular exosome)|rcsb pdb:6G4W|interpro:IPR000630(Ribosomal protein S8)|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|interpro:IPR035987|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|mint:P62244|rcsb pdb:4UG0|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:4V6X|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-72695|reactome:R-HSA-975957|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6ZM7|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|refseq:NP_001010.2|refseq:NP_001025180.1	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:Qdnhk7yvoFFYcRq5kEi7GQILaxs9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P62277	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-351850|uniprotkb:P19116|uniprotkb:Q02546|uniprotkb:Q29200|uniprotkb:Q498Y0|uniprotkb:B2R549|ensembl:ENSP00000435777	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:rs13_human(display_long)|uniprotkb:RPS13(gene name)|psi-mi:RPS13(display_short)|uniprotkb:Small ribosomal subunit protein uS15(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001008.1|ensembl:ENSG00000110700(gene)|ensembl:ENST00000525634(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR000589(Ribosomal protein S15)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR012606(Ribosomal protein S13/S15, N-terminal)|interpro:IPR023029|mint:P62277|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6OM7|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:GmlWYkXKxX6YwpEtzNABb+ZcytI9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:O43809	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-355720|uniprotkb:Q6IB85|uniprotkb:Q6NE84|ensembl:ENSP00000300291	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:cpsf5_human(display_long)|uniprotkb:NUDT21(gene name)|psi-mi:NUDT21(display_short)|uniprotkb:CFIM25(gene name synonym)|uniprotkb:CPSF25(gene name synonym)|uniprotkb:CPSF5(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 25 kDa subunit(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 21(gene name synonym)|uniprotkb:Cleavage factor Im complex 25 kDa subunit(gene name synonym)|uniprotkb:Nudix hydrolase 21(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_008937.1|ensembl:ENSG00000167005(gene)|ensembl:ENST00000300291(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006397"(mRNA processing)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0031439"(positive regulation of mRNA cleavage)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042382"(paraspeckles)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1900365"(positive regulation of mRNA polyadenylation)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:2000738"(positive regulation of stem cell differentiation)|go:"GO:2000975"(positive regulation of pro-B cell differentiation)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR016706(Cleavage and polyadenylation specificity factor, 25 kDa subunit)|mint:O43809|rcsb pdb:2CL3|rcsb pdb:2J8Q|rcsb pdb:3BAP|rcsb pdb:3BHO|rcsb pdb:3MDG|rcsb pdb:3MDI|rcsb pdb:3N9U|rcsb pdb:3P5T|rcsb pdb:3P6Y|rcsb pdb:3Q2S|rcsb pdb:3Q2T|rcsb pdb:5R4P|rcsb pdb:5R4Q|rcsb pdb:5R4R|rcsb pdb:5R4S|rcsb pdb:5R4T|rcsb pdb:5R4U|rcsb pdb:5R64|rcsb pdb:5R65|rcsb pdb:5R66|rcsb pdb:5R67|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|dip:DIP-42502N	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:Acad4mYVuS+Eox+X2CH8PYUkGAA9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9NZB2	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1171960|uniprotkb:A6NGU0|uniprotkb:O60649|uniprotkb:Q14688|uniprotkb:Q4VXF4|uniprotkb:Q4VXF5|uniprotkb:Q4VXG2|uniprotkb:Q96I21|uniprotkb:Q9NZB1|uniprotkb:C4AMC6|uniprotkb:Q86V69|intact:EBI-2560129|ensembl:ENSP00000277165	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:f120a_human(display_long)|uniprotkb:Protein FAM120A(gene name synonym)|uniprotkb:FAM120A(gene name)|psi-mi:FAM120A(display_short)|uniprotkb:C9orf10(gene name synonym)|uniprotkb:KIAA0183(gene name synonym)|uniprotkb:OSSA(gene name synonym)|uniprotkb:Oxidative stress-associated Src activator(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_055427.2|refseq:XP_011516714.1|refseq:NP_001273651.1|refseq:NP_001273652.1|refseq:NP_001273653.1|ensembl:ENSG00000048828(gene)|ensembl:ENST00000277165(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|interpro:IPR026784|interpro:IPR029060|mint:Q9NZB2	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:rUAiAHBq/d4CZZ0K56M5fkb4+dA9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:O75477	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-359299|uniprotkb:B0QZ42|uniprotkb:Q53HV0|ensembl:ENSP00000384900|ensembl:ENSP00000410964|intact:EBI-21351077|uniprotkb:D3DR65	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:erln1_human(display_long)|uniprotkb:KEO4(gene name synonym)|uniprotkb:ERLIN1(gene name)|psi-mi:ERLIN1(display_short)|uniprotkb:C10orf69(gene name synonym)|uniprotkb:KE04(gene name synonym)|uniprotkb:SPFH1(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 1(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1(gene name synonym)|uniprotkb:Protein KE04(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001094096.1|refseq:NP_006450.2|ensembl:ENSG00000107566(gene)|ensembl:ENST00000407654(transcript)|ensembl:ENST00000421367(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O75477|reactome:R-HSA-382556|reactome:R-HSA-5678895|refseq:NP_001334786.1|refseq:NP_001334788.1|refseq:NP_001334789.1|refseq:NP_001334790.1	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:HycFhL5qL5GLmaIIc9NtTcBbu1M9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P31689	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-347834|ensembl:ENSP00000369127|uniprotkb:Q5T7Q0|uniprotkb:Q86TL9	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:dnja1_human(display_long)|uniprotkb:DNAJA1(gene name)|psi-mi:DNAJA1(display_short)|uniprotkb:DNAJ2(gene name synonym)|uniprotkb:HDJ2(gene name synonym)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:HSPF4(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 4(gene name synonym)|uniprotkb:DnaJ protein homolog 2(gene name synonym)|uniprotkb:Human DnaJ protein 2(gene name synonym)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:HSDJ(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSG00000086061(gene)|ensembl:ENST00000330899(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009408"(response to heat)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:1901998"(toxin transport)|go:"GO:1903748"(negative regulation of establishment of protein localization to mitochondrion)|go:"GO:1905259"(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:P31689|rcsb pdb:2LO1|rcsb pdb:2M6Y|reactome:R-HSA-3371497|rcsb pdb:6E8M|refseq:NP_001530.1	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:YEHeLHYaG2ON2gwuFfqt9Le1Drg9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P07339	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2115097|uniprotkb:Q6IB57|ensembl:ENSP00000236671	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:catd_human(display_long)|uniprotkb:CTSD(gene name)|psi-mi:CTSD(display_short)|uniprotkb:CPSD(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001900.1|dip:DIP-43906N|ensembl:ENSG00000117984(gene)|ensembl:ENST00000236671(transcript)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0008233"(peptidase activity)|go:"GO:0010008"(endosome membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042470"(melanosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070001"(aspartic-type peptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001461(Peptidase A1)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR012848(Propeptide, peptidase A1)|interpro:IPR021109|interpro:IPR033121|interpro:IPR033144|mint:P07339|rcsb pdb:1LYA|rcsb pdb:1LYB|rcsb pdb:1LYW|rcsb pdb:4OBZ|rcsb pdb:4OC6|rcsb pdb:4OD9|reactome:R-HSA-1442490|reactome:R-HSA-2022377|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-9018519	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:M1qLQBlL2DSCZiAwIPee9Vza3dU9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P0DP23	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-25817233|ensembl:ENSP00000349467|intact:EBI-28973196|uniprotkb:P02593|uniprotkb:P62158|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q13942|uniprotkb:Q53S29|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q96HK3	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:calm1_human(display_long)|uniprotkb:CALM1(gene name)|psi-mi:CALM1(display_short)|uniprotkb:CALM(gene name synonym)|uniprotkb:CAM(gene name synonym)|uniprotkb:CAM1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	rcsb pdb:2I08|rcsb pdb:2JZI|rcsb pdb:2K0E|rcsb pdb:2K0F|rcsb pdb:2K0J|rcsb pdb:2K61|rcsb pdb:2KNE|rcsb pdb:2KUG|rcsb pdb:2KUH|rcsb pdb:2L53|rcsb pdb:2L7L|rcsb pdb:2LGF|rcsb pdb:2LL6|rcsb pdb:2LL7|rcsb pdb:2LQC|rcsb pdb:2LQP|rcsb pdb:2LV6|rcsb pdb:2M0J|rcsb pdb:2M0K|rcsb pdb:2M55|rcsb pdb:2MG5|rcsb pdb:2N27|rcsb pdb:2N6A|rcsb pdb:2N77|rcsb pdb:2N8J|rcsb pdb:2R28|rcsb pdb:2V01|rcsb pdb:2V02|rcsb pdb:2VAY|rcsb pdb:2HF5|rcsb pdb:2W73|rcsb pdb:2WEL|rcsb pdb:2X0G|go:"GO:0098901"(regulation of cardiac muscle cell action potential)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:1901842"(negative regulation of high voltage-gated calcium channel activity)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|go:"GO:1902494"(catalytic complex)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P0DP23|rcsb pdb:1AJI|rcsb pdb:1CDL|rcsb pdb:1CLL|rcsb pdb:1CTR|rcsb pdb:1IWQ|rcsb pdb:1J7O|rcsb pdb:1J7P|rcsb pdb:1K90|go:"GO:0097718"(disordered domain specific binding)|rcsb pdb:1K93|rcsb pdb:1L7Z|rcsb pdb:1LVC|ensembl:ENSG00000198668(gene)|ensembl:ENST00000356978(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030017"(sarcomere)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030426"(growth cone)|go:"GO:0031432"(titin binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0031982"(vesicle)|go:"GO:0031997"(N-terminal myristoylation domain binding)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0043209"(myelin sheath)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:0090151"(establishment of protein localization to mitochondrial membrane)|go:"GO:0030672"(synaptic vesicle membrane)|rcsb pdb:1PK0|rcsb pdb:1S26|rcsb pdb:1SK6|rcsb pdb:1SW8|rcsb pdb:1UP5|rcsb pdb:1WRZ|rcsb pdb:1XFU|rcsb pdb:1XFV|rcsb pdb:1XFW|rcsb pdb:1XFX|rcsb pdb:1XFY|rcsb pdb:1XFZ|rcsb pdb:1Y6W|rcsb pdb:1YR5|rcsb pdb:1YRT|rcsb pdb:1YRU|rcsb pdb:1ZOT|rcsb pdb:1ZUZ|rcsb pdb:2BE6|rcsb pdb:1NKF|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2Y4V|rcsb pdb:3DVE|rcsb pdb:3DVJ|rcsb pdb:3DVK|rcsb pdb:3DVM|rcsb pdb:3EWT|rcsb pdb:3EWV|rcsb pdb:3G43|rcsb pdb:3HR4|rcsb pdb:3J41|rcsb pdb:3O77|rcsb pdb:3O78|rcsb pdb:3OXQ|rcsb pdb:3SUI|rcsb pdb:3UCT|rcsb pdb:3UCW|rcsb pdb:3UCY|rcsb pdb:4BW7|rcsb pdb:4BW8|rcsb pdb:4BYF|rcsb pdb:4DCK|rcsb pdb:4DJC|rcsb pdb:4GOW|rcsb pdb:4JPZ|rcsb pdb:4JQ0|rcsb pdb:4L79|rcsb pdb:4LZX|rcsb pdb:4M1L|rcsb pdb:4OVN|rcsb pdb:4Q57|rcsb pdb:4Q5U|rcsb pdb:4UMO|rcsb pdb:4UPU|rcsb pdb:4V0C|rcsb pdb:5COC|rcsb pdb:3BYA|rcsb pdb:5DBR|rcsb pdb:5DOW|rcsb pdb:5DSU|rcsb pdb:5GGM|rcsb pdb:5I0I|rcsb pdb:5J03|rcsb pdb:5J8H|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:5K7L|rcsb pdb:5K8Q|rcsb pdb:5OEO|rcsb pdb:5TP5|rcsb pdb:5TP6|rcsb pdb:5V02|rcsb pdb:5V03|rcsb pdb:5V7X|rcsb pdb:5WBX|rcsb pdb:5WC5|rcsb pdb:6B8L|rcsb pdb:6B8M|rcsb pdb:6B8N|rcsb pdb:6B8P|rcsb pdb:6B8Q|rcsb pdb:6BUT|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6CNM|rcsb pdb:6CNN|rcsb pdb:6CNO|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6DAH|rcsb pdb:6E2F|rcsb pdb:6E2G|rcsb pdb:6EEB|rcsb pdb:6FEG|rcsb pdb:6FEH|rcsb pdb:6GDK|rcsb pdb:6GDL|rcsb pdb:6HCS|rcsb pdb:6HR1|rcsb pdb:6JI8|rcsb pdb:6JII|rcsb pdb:6JIU|rcsb pdb:6JIY|rcsb pdb:6JRS|rcsb pdb:6JV2|rcsb pdb:6K4K|rcsb pdb:6K4L|rcsb pdb:6K4R|rcsb pdb:6M2W|rcsb pdb:6M7H|rcsb pdb:6MUD|rcsb pdb:6MUE|rcsb pdb:6N5W|rcsb pdb:6O5G|rcsb pdb:6OS4|rcsb pdb:6PAW|rcsb pdb:6PBX|rcsb pdb:6PBY|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|rcsb pdb:6X32|rcsb pdb:6X33|rcsb pdb:6X35|rcsb pdb:6X36|rcsb pdb:6XXX|rcsb pdb:6XY3|rcsb pdb:6XYR|rcsb pdb:6Y4P|rcsb pdb:6Y94|rcsb pdb:6Y95|rcsb pdb:6YNS|rcsb pdb:6YNU|rcsb pdb:6ZBI|rcsb pdb:7KL5|reactome:R-HSA-111932|reactome:R-HSA-111933|reactome:R-HSA-111957|reactome:R-HSA-111997|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-442982|reactome:R-HSA-445355|reactome:R-HSA-451308|reactome:R-HSA-1474151|reactome:R-HSA-5210891|reactome:R-HSA-5218920|reactome:R-HSA-5218921|reactome:R-HSA-163615|reactome:R-HSA-180024|reactome:R-HSA-5576892|reactome:R-HSA-1855204|reactome:R-HSA-2025928|reactome:R-HSA-5578775|reactome:R-HSA-5607763|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-203615|reactome:R-HSA-2151201|reactome:R-HSA-2514859|reactome:R-HSA-5673000|reactome:R-HSA-2672351|reactome:R-HSA-5673001|reactome:R-HSA-6802946|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-70221|reactome:R-HSA-8876725|reactome:R-HSA-9009391|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-438066|reactome:R-HSA-442720|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-936837|reactome:R-HSA-9617324|reactome:R-HSA-9619229|reactome:R-HSA-9619483|reactome:R-HSA-9620244|reactome:R-HSA-9648002|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9664323|reactome:R-HSA-983695|reactome:R-HSA-442729|refseq:NP_001316851.1|refseq:NP_001734.1|refseq:NP_005175.2|refseq:NP_008819.1	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:tTYcOd9bOh211njZVz7cYVybAMQ9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q05682	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1642116|uniprotkb:Q13978|uniprotkb:Q13979|uniprotkb:Q14741|uniprotkb:Q14742|uniprotkb:Q9UD91|uniprotkb:A8K0X1|ensembl:ENSP00000354826	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:cald1_human(display_long)|uniprotkb:CALD1(gene name)|psi-mi:CALD1(display_short)|uniprotkb:CAD(gene name synonym)|uniprotkb:CDM(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_004333.1|refseq:NP_149129.2|refseq:NP_149130.1|refseq:NP_149131.1|refseq:NP_149347.2|refseq:XP_016868140.1|refseq:XP_016868141.1|ensembl:ENSG00000122786(gene)|ensembl:ENST00000361675(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030478"(actin cap)|go:"GO:0045296"(cadherin binding)|go:"GO:0051017"(actin filament bundle assembly)|interpro:IPR006017(Caldesmon)|interpro:IPR006018(Caldesmon and lymphocyte specific protein)|mint:Q05682|reactome:R-HSA-445355	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:fvHmtqnSPixs/3150s7LOA1Bvpw9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q13813	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-351450|uniprotkb:Q13186|uniprotkb:Q15324|uniprotkb:Q16606|uniprotkb:Q59EF1|uniprotkb:Q5VXV5|uniprotkb:Q5VXV6|uniprotkb:Q7Z6M5|uniprotkb:Q9P0V0|intact:EBI-4404719|intact:EBI-28985930|ensembl:ENSP00000361816	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:sptn1_human(display_long)|uniprotkb:SPTAN1(gene name)|psi-mi:SPTAN1(display_short)|uniprotkb:SPTA2(gene name synonym)|uniprotkb:Alpha-II spectrin(gene name synonym)|uniprotkb:Fodrin alpha chain(gene name synonym)|uniprotkb:NEAS(gene name synonym)|uniprotkb:Spectrin, non-erythroid alpha subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001123910.1|refseq:NP_001182461.1|refseq:NP_003118.2|ensembl:ENSG00000197694(gene)|ensembl:ENST00000372731(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0008091"(spectrin)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035825|interpro:IPR036028|mint:Q13813|rcsb pdb:2FOT|rcsb pdb:3F31|rcsb pdb:3FB2|rcsb pdb:5FW9|rcsb pdb:5FWB|rcsb pdb:5FWC|rcsb pdb:6ZEH|reactome:R-HSA-264870|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9662360|reactome:R-HSA-9662361|ensembl:ENST00000358161|ensembl:ENSP00000350882|ensembl:ENSP00000361816|ensembl:ENST00000372739|ensembl:ENSP00000361824|dip:DIP-33141N	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:3d5XlsH+PSg32qNR/ZiooAJ/wH89606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P12956	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-353208|ensembl:ENSP00000352257|ensembl:ENSP00000353192|ensembl:ENSP00000384257|intact:EBI-2843064|uniprotkb:Q6FG89|uniprotkb:Q9UCQ2|uniprotkb:Q9UCQ3|intact:EBI-8456785|intact:MINT-8429298|uniprotkb:B1AHC8	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:xrcc6_human(display_long)|uniprotkb:XRCC6(gene name)|psi-mi:XRCC6(display_short)|uniprotkb:G22P1(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 70 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p70(gene name synonym)|uniprotkb:70 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 75 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein XRCC6(gene name synonym)|uniprotkb:X-ray repair complementing defective repair in Chinese hamster cells 6(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 1(gene name synonym)|uniprotkb:5'-deoxyribose-5-phosphate lyase Ku70(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR006165(DNA helicase, ATP-dependent, Ku70 subunit)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR027388|interpro:IPR036361|interpro:IPR036465|mint:P12956|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1JJR|rcsb pdb:3RZX|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZHA|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|rcsb pdb:6ZHE|rcsb pdb:7AXZ|interpro:IPR003034(DNA-binding SAP)|rcsb pdb:7K0Y|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000196419(gene)|go:"GO:0005829"(cytosol)|go:"GO:0006266"(DNA ligation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|ensembl:ENST00000359308(transcript)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|ensembl:ENST00000360079(transcript)|ensembl:ENST00000405878(transcript)|go:"GO:0016020"(membrane)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|refseq:NP_001460.1|refseq:NP_001275906.1|refseq:NP_001275905.1|dip:DIP-24188N	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:45wj3HmNJ4dfVgw0zc2r3AUZ0Dw9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P07951	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-352633|uniprotkb:P06468|uniprotkb:Q13894|uniprotkb:Q53FM4|uniprotkb:A6NM85|uniprotkb:Q5TCU4|uniprotkb:Q5TCU7|uniprotkb:Q9UH67|ensembl:ENSP00000496494	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:tpm2_human(display_long)|uniprotkb:TPM2(gene name)|psi-mi:TPM2(display_short)|uniprotkb:TMSB(gene name synonym)|uniprotkb:Tropomyosin-2(gene name synonym)|uniprotkb:Beta-tropomyosin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_003280.2|refseq:NP_998839.1|mint:P07951|reactome:R-HSA-390522|reactome:R-HSA-445355|ensembl:ENSG00000198467(gene)|ensembl:ENST00000645482(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051015"(actin filament binding)|interpro:IPR000533(Tropomyosin)|refseq:XP_016870580.1	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:uMqEpVZJ9ezKmeA67qQLCWBd/zo9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9NYL9	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-352614|ensembl:ENSP00000308753|uniprotkb:Q9NT43|uniprotkb:Q9NZR0|uniprotkb:B2R6G7	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:tmod3_human(display_long)|uniprotkb:TMOD3(gene name)|psi-mi:TMOD3(display_short)|uniprotkb:Ubiquitous tropomodulin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSG00000138594(gene)|ensembl:ENST00000308580(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005912"(adherens junction)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0030016"(myofibril)|go:"GO:0030239"(myofibril assembly)|refseq:NP_055362.1|go:"GO:0048821"(erythrocyte development)|go:"GO:0051694"(pointed-end actin filament capping)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1901992"(positive regulation of mitotic cell cycle phase transition)|interpro:IPR004934(Tropomodulin)|interpro:IPR030133|interpro:IPR032675|mint:Q9NYL9|reactome:R-HSA-390522|reactome:R-HSA-9013418|reactome:R-HSA-9696264|refseq:XP_016877576.1|refseq:XP_016877577.1	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:crEfCAAepSPAE8ByBpD4Sr14P5I9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P07996	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2530274|uniprotkb:A8K6H4|uniprotkb:B9EGH6|uniprotkb:Q15667|ensembl:ENSP00000260356|uniprotkb:B4E3J7|uniprotkb:Q59E99	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:tsp1_human(display_long)|uniprotkb:THBS1(gene name)|psi-mi:THBS1(display_short)|uniprotkb:TSP(gene name synonym)|uniprotkb:TSP1(gene name synonym)|uniprotkb:Glycoprotein G(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSG00000137801(gene)|ensembl:ENST00000260356(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002581"(negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II)|go:"GO:0002605"(negative regulation of dendritic cell antigen processing and presentation)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007155"(cell adhesion)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009749"(response to glucose)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0010748"(negative regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0010751"(negative regulation of nitric oxide mediated signal transduction)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0010757"(negative regulation of plasminogen activation)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0016477"(cell migration)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030141"(secretory granule)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032570"(response to progesterone)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0008201"(heparin binding)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043236"(laminin binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050431"(transforming growth factor beta binding)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0032914"(positive regulation of transforming growth factor beta1 production)|go:"GO:0033574"(response to testosterone)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070051"(fibrinogen binding)|go:"GO:0070052"(collagen V binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2001027"(negative regulation of endothelial cell chemotaxis)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003367(Thrombospondin type 3 repeat)|interpro:IPR008859(Thrombospondin, C-terminal)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017897|interpro:IPR028499|interpro:IPR028974|interpro:IPR036383|mint:P07996|rcsb pdb:1LSL|rcsb pdb:1UX6|rcsb pdb:1Z78|rcsb pdb:1ZA4|rcsb pdb:2ERF|rcsb pdb:2ES3|rcsb pdb:2OUH|rcsb pdb:2OUJ|rcsb pdb:3R6B|rcsb pdb:5FOE|reactome:R-HSA-114608|reactome:R-HSA-186797|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-5083635|reactome:R-HSA-5173214|reactome:R-HSA-8936459|refseq:NP_003237.2|dip:DIP-1037N	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:wqgWk4yWvhfEjrD+H6BdJrJgVgg9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:O95425	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-487145|uniprotkb:O60611|uniprotkb:O60612|uniprotkb:Q5VZK5|uniprotkb:Q5VZK6|uniprotkb:Q9H1R7|uniprotkb:D3DRW9|ensembl:ENSP00000348128|uniprotkb:M1J557	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:svil_human(display_long)|uniprotkb:Archvillin(gene name synonym)|uniprotkb:p205/p250(gene name synonym)|uniprotkb:SVIL(gene name)|psi-mi:SVIL(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	go:"GO:0007519"(skeletal muscle tissue development)|refseq:NP_003165.2|refseq:NP_068506.2|ensembl:ENSG00000197321(gene)|ensembl:ENST00000355867(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|interpro:IPR007123(Gelsolin region)|interpro:IPR015628(Supervillin)|interpro:IPR029006|interpro:IPR036886|mint:O95425|rcsb pdb:2K6M|rcsb pdb:2K6N|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0042995"(cell projection)|go:"GO:0043034"(costamere)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR003128(Villin headpiece)|interpro:IPR007122(Gelsolin)	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:5FaBAFdOX+nPJzTwEdBt8e5Keng9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q04837	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-353460|ensembl:ENSP00000265304|ensembl:ENSP00000419388|ensembl:ENSP00000419541|ensembl:ENSP00000419665|ensembl:ENSP00000420485|ensembl:ENSP00000458815|ensembl:ENSP00000459208|ensembl:ENSP00000459367|ensembl:ENSP00000460028|ensembl:ENSP00000461884|ensembl:ENSP00000480488	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:ssbp_human(display_long)|uniprotkb:SSBP1(gene name)|psi-mi:SSBP1(display_short)|uniprotkb:SSBP(gene name synonym)|uniprotkb:PWP1-interacting protein 17(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_003134.1|refseq:NP_001243439.1|refseq:NP_001243440.1|refseq:NP_001243441.1|refseq:NP_001243442.1|ensembl:ENSG00000106028(gene)|ensembl:ENSG00000262771(gene)|ensembl:ENST00000265304(transcript)|ensembl:ENST00000465582(transcript)|ensembl:ENST00000481508(transcript)|ensembl:ENST00000484178(transcript)|ensembl:ENST00000498107(transcript)|ensembl:ENST00000570667(transcript)|ensembl:ENST00000571430(transcript)|ensembl:ENST00000574199(transcript)|ensembl:ENST00000575059(transcript)|ensembl:ENST00000576834(transcript)|ensembl:ENST00000612337(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|go:"GO:1905776"(positive regulation of DNA helicase activity)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:Q04837|rcsb pdb:1S3O|rcsb pdb:2DUD|rcsb pdb:3ULL|rcsb pdb:6RUP|reactome:R-HSA-2151201	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:W/7kbgBRtYcjJfr2XbA1OK9BOS49606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q69YQ0	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-351113|uniprotkb:O15081|intact:EBI-10965349|uniprotkb:B7Z758|uniprotkb:F5H1H6|ensembl:ENSP00000325785|ensembl:ENSP00000393363|ensembl:ENSP00000439633	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:cytsa_human(display_long)|uniprotkb:SPECC1L(gene name)|psi-mi:SPECC1L(display_short)|uniprotkb:Renal carcinoma antigen NY-REN-22(gene name synonym)|uniprotkb:CYTSA(gene name synonym)|uniprotkb:KIAA0376(gene name synonym)|uniprotkb:Sperm antigen with calponin homology and coiled-coil domains 1-like(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_056145.4|refseq:NP_001241661.2|dip:DIP-33173N|ensembl:ENSG00000100014(gene)|ensembl:ENST00000314328(transcript)|ensembl:ENST00000437398(transcript)|ensembl:ENST00000541492(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005921"(gap junction)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0051301"(cell division)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR036872|interpro:IPR040166|mint:Q69YQ0	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:iYg2RCRo/dMtmwyppU7ywkhkolI9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P62851	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-353054|ensembl:ENSP00000435096|ensembl:ENSP00000486392|uniprotkb:P25111|uniprotkb:B2R4M7	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:rs25_human(display_long)|uniprotkb:RPS25(gene name)|psi-mi:RPS25(display_short)|uniprotkb:Small ribosomal subunit protein eS25(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSG00000118181(gene)|ensembl:ENSG00000280831(gene)|ensembl:ENST00000527673(transcript)|ensembl:ENST00000628770(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004977(Ribosomal protein S25)|interpro:IPR036388|mint:P62851|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y0G|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|rcsb pdb:6ZXD|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|rcsb pdb:6ZXE|reactome:R-HSA-9010553|reactome:R-HSA-9633012|rcsb pdb:6ZXF|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|refseq:NP_001019.1	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:7TqA4Q6+6VMzrzaUrACbwtJKfOM9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q0ZGT2	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-351705|uniprotkb:B4DPZ7|uniprotkb:A0PJ84|uniprotkb:Q0D2H2|uniprotkb:Q14CC2|uniprotkb:Q14CC3|uniprotkb:Q16081|uniprotkb:Q7Z2X0|uniprotkb:Q96DL0|uniprotkb:Q9Y2V1|intact:EBI-2555043|ensembl:ENSP00000333938	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:nexn_human(display_long)|uniprotkb:F-actin-binding protein(gene name synonym)|uniprotkb:Nelin(gene name synonym)|uniprotkb:NEXN(gene name)|psi-mi:NEXN(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001165780.1|refseq:NP_653174.3|ensembl:ENSG00000162614(gene)|ensembl:ENST00000334785(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0051015"(actin filament binding)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR043204|mint:Q0ZGT2|go:"GO:0008307"(structural constituent of muscle)|refseq:XP_005271380.1	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:YtKRiGq1tjrPhdFzpS5TKVn3So89606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9NXR1	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-941227|uniprotkb:Q49AQ2|ensembl:ENSP00000379642|ensembl:ENSP00000379643|ensembl:ENSP00000488050|ensembl:ENSP00000488199|ensembl:ENSP00000501936|ensembl:ENSP00000502160|ensembl:ENSP00000502354|ensembl:ENSP00000502635	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:nde1_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short)|uniprotkb:NUDE(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001137451.1|refseq:NP_060138.1|refseq:XP_016878838.1|refseq:XP_016878845.1|ensembl:ENSG00000072864(gene)|ensembl:ENSG00000275911(gene)|ensembl:ENST00000396354(transcript)|ensembl:ENST00000396355(transcript)|ensembl:ENST00000631844(transcript)|ensembl:ENST00000631923(transcript)|ensembl:ENST00000674554(transcript)|ensembl:ENST00000674888(transcript)|ensembl:ENST00000675926(transcript)|ensembl:ENST00000675951(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0001764"(neuron migration)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051642"(centrosome localization)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|mint:Q9NXR1|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9648025	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:H769EmQerGWsy6Zud3BBzkAuQw49606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9UHB6	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-351479|uniprotkb:Q2TAN7|uniprotkb:Q9BVF2|uniprotkb:Q9H8J1|uniprotkb:Q9HBN5|uniprotkb:Q9NX96|uniprotkb:Q9NXC3|uniprotkb:Q9NXU6|uniprotkb:Q9P0H8|uniprotkb:Q9UHB5|uniprotkb:B2RB09|ensembl:ENSP00000340184|uniprotkb:Q59FE8	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:lima1_human(display_long)|uniprotkb:PP624(orf name)|uniprotkb:LIMA1(gene name)|psi-mi:LIMA1(display_short)|uniprotkb:SREBP3(gene name synonym)|uniprotkb:Epithelial protein lost in neoplasm(gene name synonym)|uniprotkb:EPLIN(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001107018.1|refseq:NP_001107019.1|refseq:NP_057441.1|refseq:XP_011536757.1|ensembl:ENSG00000050405(gene)|ensembl:ENST00000341247(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0030299"(intestinal cholesterol absorption)|go:"GO:0030835"(negative regulation of actin filament depolymerization)|go:"GO:0031526"(brush border membrane)|go:"GO:0031529"(ruffle organization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR028740|mint:Q9UHB6|rcsb pdb:2D8Y|refseq:NP_001230704.1|refseq:XP_016874919.1|dip:DIP-29633N	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:sHqhe21LVzLJXgDMH6IcWukKNHE9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P23458	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1383438|uniprotkb:Q59GQ2|uniprotkb:Q9UD26|ensembl:ENSP00000343204|ensembl:ENSP00000499884|ensembl:ENSP00000499900|ensembl:ENSP00000500296|ensembl:ENSP00000500485|ensembl:ENSP00000500841	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:jak1_human(display_long)|uniprotkb:JAK1(gene name)|psi-mi:JAK1(display_short)|uniprotkb:JAK1A(gene name synonym)|uniprotkb:JAK1B(gene name synonym)|uniprotkb:Janus kinase 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001308785.1|refseq:NP_002218.2|refseq:NP_001307852.1|refseq:NP_001308781.1|refseq:NP_001308782.1|refseq:NP_001308783.1|refseq:NP_001308784.1|dip:DIP-133N|reactome:R-HSA-912526|reactome:R-HSA-912694|reactome:R-HSA-9674555|reactome:R-HSA-9679191|reactome:R-HSA-9705462|reactome:R-HSA-909733|ensembl:ENSG00000162434(gene)|ensembl:ENST00000342505(transcript)|ensembl:ENST00000671929(transcript)|ensembl:ENST00000671954(transcript)|ensembl:ENST00000672179(transcript)|ensembl:ENST00000672247(transcript)|ensembl:ENST00000672434(transcript)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005131"(growth hormone receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0034112"(positive regulation of homotypic cell-cell adhesion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038110"(interleukin-2-mediated signaling pathway)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019748|interpro:IPR019749|interpro:IPR020635|interpro:IPR020776|interpro:IPR035963|interpro:IPR036860|interpro:IPR041046|interpro:IPR041155|interpro:IPR041381|mint:P23458|rcsb pdb:3EYG|rcsb pdb:3EYH|rcsb pdb:4E4L|rcsb pdb:4E4N|rcsb pdb:4E5W|rcsb pdb:4EHZ|rcsb pdb:4EI4|rcsb pdb:4FK6|rcsb pdb:4GS0|rcsb pdb:4I5C|rcsb pdb:4IVB|rcsb pdb:4IVC|rcsb pdb:4IVD|rcsb pdb:4K6Z|rcsb pdb:4K77|rcsb pdb:4L00|rcsb pdb:4L01|rcsb pdb:5E1E|rcsb pdb:5HX8|rcsb pdb:5IXD|rcsb pdb:5IXI|rcsb pdb:5KHW|rcsb pdb:5KHX|rcsb pdb:5L04|rcsb pdb:5WO4|rcsb pdb:6AAH|rcsb pdb:6BBU|rcsb pdb:6C7Y|rcsb pdb:6DBN|rcsb pdb:6ELR|rcsb pdb:6GGH|rcsb pdb:6HZU|rcsb pdb:6N77|rcsb pdb:6N78|rcsb pdb:6N79|rcsb pdb:6N7A|rcsb pdb:6N7B|rcsb pdb:6N7C|rcsb pdb:6N7D|rcsb pdb:6RSB|rcsb pdb:6RSC|rcsb pdb:6RSD|rcsb pdb:6RSE|rcsb pdb:6RSH|rcsb pdb:6SM8|rcsb pdb:6SMB|rcsb pdb:6TPE|rcsb pdb:6TPF|rcsb pdb:6W8L|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-1169408|reactome:R-HSA-1266695|reactome:R-HSA-449836|reactome:R-HSA-5673001|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-6788467|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8854691|reactome:R-HSA-8983432|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9020558|reactome:R-HSA-9020591|reactome:R-HSA-9020956|reactome:R-HSA-9020958	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:gEEiBAxwXnGGFWwO7OC0l0KjmSY9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q96J02	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1564678|uniprotkb:O43584|uniprotkb:Q5TEL0|uniprotkb:Q96F66|uniprotkb:Q9BY75|uniprotkb:Q9H451|uniprotkb:Q9H4U5|uniprotkb:A6NEW4|uniprotkb:Q5QP37|uniprotkb:E1P5P3|uniprotkb:B4E234|uniprotkb:F5H217|ensembl:ENSP00000262650|ensembl:ENSP00000499786	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:itch_human(display_long)|uniprotkb:HECT-type E3 ubiquitin transferase Itchy homolog(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 4(gene name synonym)|uniprotkb:NFE2-associated polypeptide 1(gene name synonym)|uniprotkb:ITCH(gene name)|psi-mi:ITCH(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001311126.1|refseq:NP_113671.3|refseq:NP_001244066.1|refseq:NP_001311127.1|refseq:NP_001244067.1|refseq:XP_016883578.1|refseq:XP_016883580.1|dip:DIP-29849N|ensembl:ENSG00000078747(gene)|ensembl:ENST00000262650(transcript)|ensembl:ENST00000665346(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0002669"(positive regulation of T cell anergy)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016874"(ligase activity)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035519"(protein K29-linked ubiquitination)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045236"(CXCR chemokine receptor binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046642"(negative regulation of alpha-beta T cell proliferation)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070423"(nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090085"(regulation of protein deubiquitination)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1990763"(arrestin family protein binding)|go:"GO:2000646"(positive regulation of receptor catabolic process)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:Q96J02|rcsb pdb:2DMV|rcsb pdb:2KYK|rcsb pdb:2NQ3|rcsb pdb:2P4R|rcsb pdb:2YSF|rcsb pdb:3TUG|rcsb pdb:4ROF|rcsb pdb:5C7M|rcsb pdb:5CQ2|rcsb pdb:5DWS|rcsb pdb:5DZD|rcsb pdb:5SXP|reactome:R-HSA-1253288|reactome:R-HSA-168638|reactome:R-HSA-2122948|reactome:R-HSA-5610780|reactome:R-HSA-5632684|reactome:R-HSA-8939236|reactome:R-HSA-936440|reactome:R-HSA-983168	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:JyySOfI+ZHOI1mvdxWDGN6njgCY9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P06396	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-351506|uniprotkb:Q8WVV7|ensembl:ENSP00000362924|uniprotkb:Q5T0I2|uniprotkb:A8MUD1|uniprotkb:B7Z373|uniprotkb:A2A418|uniprotkb:A8MYN7|uniprotkb:B7Z5V1|uniprotkb:F5H1A8	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:gels_human(display_long)|uniprotkb:GSN(gene name)|psi-mi:GSN(display_short)|uniprotkb:Actin-depolymerizing factor(gene name synonym)|uniprotkb:Brevin(gene name synonym)|uniprotkb:AGEL(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_000168.1|refseq:NP_001121134.1|refseq:NP_001121136.1|refseq:NP_001121137.1|refseq:NP_001121138.1|refseq:NP_001121139.1|refseq:NP_937895.1|refseq:XP_011516888.1|refseq:XP_011516889.1|refseq:XP_011516890.1|refseq:XP_011516891.1|refseq:XP_011516892.1|refseq:XP_011516893.1|refseq:XP_011516894.1|refseq:XP_011516895.1|ensembl:ENSG00000148180(gene)|ensembl:ENST00000373818(transcript)|go:"GO:0002102"(podosome)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007417"(central nervous system development)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014891"(striated muscle atrophy)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030478"(actin cap)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031648"(protein destabilization)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0036313"(phosphatidylinositol 3-kinase catalytic subunit binding)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0045010"(actin nucleation)|go:"GO:0045159"(myosin II binding)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051127"(positive regulation of actin nucleation)|go:"GO:0051693"(actin filament capping)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071801"(regulation of podosome assembly)|go:"GO:0072562"(blood microparticle)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0090527"(actin filament reorganization)|go:"GO:0097017"(renal protein absorption)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:1902174"(positive regulation of keratinocyte apoptotic process)|go:"GO:1903903"(regulation of establishment of T cell polarity)|go:"GO:1903906"(regulation of plasma membrane raft polarization)|go:"GO:1903909"(regulation of receptor clustering)|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030004|mint:P06396|rcsb pdb:1C0F|rcsb pdb:1C0G|rcsb pdb:1D4X|rcsb pdb:1DEJ|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1KCQ|rcsb pdb:1MDU|rcsb pdb:1NLV|rcsb pdb:1NM1|rcsb pdb:1NMD|rcsb pdb:1P8X|rcsb pdb:1SOL|rcsb pdb:1T44|rcsb pdb:1YAG|rcsb pdb:1YVN|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FH1|rcsb pdb:2FH2|rcsb pdb:2FH3|rcsb pdb:2FH4|rcsb pdb:3A5L|rcsb pdb:3A5M|rcsb pdb:3A5N|rcsb pdb:3A5O|rcsb pdb:3CI5|rcsb pdb:3CIP|rcsb pdb:3CJB|rcsb pdb:3CJC|rcsb pdb:3FFK|rcsb pdb:3FFN|rcsb pdb:3TU5|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4S10|rcsb pdb:4Z94|rcsb pdb:5DD2|rcsb pdb:5FAE|rcsb pdb:5FAF|rcsb pdb:5H3M|rcsb pdb:5H3N|rcsb pdb:5O2Z|rcsb pdb:5UBO|rcsb pdb:5ZZ0|rcsb pdb:6H1F|rcsb pdb:6JCO|rcsb pdb:6JEG|rcsb pdb:6JEH|rcsb pdb:6LJE|rcsb pdb:6LJF|rcsb pdb:6Q9R|rcsb pdb:6Q9Z|rcsb pdb:6QBF|rcsb pdb:1P8Z|rcsb pdb:6QW3|reactome:R-HSA-264870|reactome:R-HSA-6798695|reactome:R-HSA-9662361|reactome:R-HSA-977225|refseq:NP_001244958.1|refseq:NP_001244959.1|refseq:NP_001121135.2|refseq:XP_005252000.1|refseq:XP_005252001.1|refseq:XP_005252002.1|refseq:XP_006717142.1|refseq:XP_016870135.1|refseq:XP_016870136.1|refseq:XP_016870137.1|dip:DIP-2196N	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:uACf9A+H6LAOAZSMGYqeDwUL1Mc9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q4V328	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-717919|uniprotkb:A6NL78|uniprotkb:Q3MJ75|uniprotkb:Q4V327|uniprotkb:Q4V330|uniprotkb:Q5HYG1|uniprotkb:Q6N046|uniprotkb:Q96DH8|uniprotkb:Q9NQ43|uniprotkb:Q9ULQ3|ensembl:ENSP00000365606	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:grap1_human(display_long)|uniprotkb:GRIPAP1(gene name)|psi-mi:GRIPAP1(display_short)|uniprotkb:KIAA1167(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_064522.3|ensembl:ENSG00000068400(gene)|ensembl:ENST00000376423(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0072562"(blood microparticle)|go:"GO:0098837"(postsynaptic recycling endosome)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098998"(extrinsic component of postsynaptic early endosome membrane)|go:"GO:0099152"(regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0099158"(regulation of recycling endosome localization within postsynapse)|go:"GO:1905244"(regulation of modification of synaptic structure)|interpro:IPR026204|mint:Q4V328|dip:DIP-47299N	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:iIGfz5XvbexX4taRlMqWYsfAVBo9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P02751	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:XP_005246463.1|dip:DIP-29547N|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019899"(enzyme binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0033622"(integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|ensembl:ENSG00000115414(gene)|ensembl:ENST00000354785(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006953"(acute-phase response)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901166"(neural crest cell migration involved in autonomic nervous system development)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9649948|reactome:R-HSA-9656223	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:4arZu49X8b+dthqaX4DIh59V8h09606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q14254	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-348613|ensembl:ENSP00000378368	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:flot2_human(display_long)|uniprotkb:FLOT2(gene name)|psi-mi:FLOT2(display_short)|uniprotkb:ESA1(gene name synonym)|uniprotkb:M17S1(gene name synonym)|uniprotkb:Epidermal surface antigen(gene name synonym)|uniprotkb:Membrane component chromosome 17 surface marker 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_004466.2|ensembl:ENSG00000132589(gene)|go:"GO:0008544"(epidermis development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016600"(flotillin complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044860"(protein localization to plasma membrane raft)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098937"(anterograde dendritic transport)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099029"(anchored component of presynaptic active zone membrane)|ensembl:ENST00000394908(transcript)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001931"(uropod)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1902992"(negative regulation of amyloid precursor protein catabolic process)|go:"GO:1903905"(positive regulation of establishment of T cell polarity)|interpro:IPR001107(Band 7 protein)|interpro:IPR027705|interpro:IPR031905|interpro:IPR036013|mint:Q14254|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8849932|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9696264|reactome:R-HSA-9696273|refseq:XP_016879883.1|refseq:XP_016879884.1	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:P9htlLzTYk+eDKKesqCEPe/1BJA9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:O75955	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-603643|ensembl:ENSP00000365569|ensembl:ENSP00000372873|ensembl:ENSP00000373056|ensembl:ENSP00000388861|ensembl:ENSP00000391438|uniprotkb:Q969J8|uniprotkb:Q9UHW1|uniprotkb:Q9UNV8|uniprotkb:B4DVY7	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:flot1_human(display_long)|uniprotkb:FLOT1(gene name)|psi-mi:FLOT1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001931"(uropod)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007409"(axonogenesis)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016600"(flotillin complex)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030027"(lamellipodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032226"(positive regulation of synaptic transmission, dopaminergic)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033227"(dsRNA transport)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034141"(positive regulation of toll-like receptor 3 signaling pathway)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044854"(plasma membrane raft assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060355"(positive regulation of cell adhesion molecule production)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:1901890"(positive regulation of cell junction assembly)|go:"GO:1903044"(protein localization to membrane raft)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR001107(Band 7 protein)|interpro:IPR027705|interpro:IPR036013|mint:O75955|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8849932|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|ensembl:ENSG00000137312(gene)|ensembl:ENSG00000206379(gene)|ensembl:ENSG00000206480(gene)|ensembl:ENSG00000230143(gene)|ensembl:ENSG00000232280(gene)|ensembl:ENST00000376389(transcript)|ensembl:ENST00000383382(transcript)|ensembl:ENST00000383562(transcript)|ensembl:ENST00000436822(transcript)|ensembl:ENST00000444632(transcript)|refseq:NP_005794.1|refseq:NP_001305804.1|refseq:XP_005248837.1	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:wRw9QYIRNJb0ZQtwjm/D+ydci8k9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q13045	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-351549|ensembl:ENSP00000491480|ensembl:ENSP00000324573|uniprotkb:B4DIL0|uniprotkb:F5H407|uniprotkb:J3QLG3	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:flii_human(display_long)|uniprotkb:FLII(gene name)|psi-mi:FLII(display_short)|uniprotkb:FLIL(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_002009.1|refseq:NP_001243193.1|ensembl:ENST00000327031(transcript)|ensembl:ENST00000638207(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030239"(myofibril assembly)|go:"GO:0034451"(centriolar satellite)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR029919|interpro:IPR032675|mint:Q13045|ensembl:ENSG00000177731(gene)|ensembl:ENSG00000284571(gene)|refseq:NP_001243194.1	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:hzls0Ir+lr0+wNsTUeIURV3fXVQ9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q01844	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-739737|uniprotkb:Q92635|uniprotkb:Q96FE8|uniprotkb:Q96MX4|uniprotkb:Q9BWA2|uniprotkb:Q5THL0|intact:EBI-28987207|ensembl:ENSP00000381031|intact:EBI-10985407|uniprotkb:B0QYK1|uniprotkb:Q96MN4	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:ews_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short)|uniprotkb:EWS(gene name synonym)|uniprotkb:EWS oncogene(gene name synonym)|uniprotkb:Ewing sarcoma breakpoint region 1 protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001156757.1|refseq:NP_005234.1|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q01844|rcsb pdb:2CPE|interpro:IPR001876(Zinc finger, RanBP2-type)|ensembl:ENSG00000182944(gene)|ensembl:ENST00000397938(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001156759.1|refseq:NP_053733.2|refseq:NP_001156758.1|ensembl:ENST00000332035|ensembl:ENSP00000331699|ensembl:ENST00000333395|ensembl:ENSP00000327456|ensembl:ENSP00000381031|ensembl:ENST00000406548|ensembl:ENSP00000385726|ensembl:ENST00000414183|ensembl:ENSP00000400142|dip:DIP-34449N	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:7PxoTjcmcdUA3clzf0eW+iCFaS49606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q92499	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-358474|ensembl:ENSP00000233084|ensembl:ENSP00000370745|ensembl:ENSP00000413767|ensembl:ENSP00000504080|uniprotkb:B4DME8|uniprotkb:B4DPN6	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:ddx1_human(display_long)|uniprotkb:DDX1(gene name)|psi-mi:DDX1(display_short)|uniprotkb:DEAD box protein 1(gene name synonym)|uniprotkb:DEAD box protein retinoblastoma(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSG00000079785(gene)|ensembl:ENST00000233084(transcript)|ensembl:ENST00000381341(transcript)|ensembl:ENST00000434671(transcript)|ensembl:ENST00000677302(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0002735"(positive regulation of myeloid dendritic cell cytokine production)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|refseq:NP_004930.1|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008143"("poly(A) binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0071920"(cleavage body)|go:"GO:0072669"(tRNA-splicing ligase complex)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR043136|mint:Q92499|rcsb pdb:4XW3|reactome:R-HSA-6784531|dip:DIP-38163N	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:n2Zv07BpuUDT32/ttDzIFXH3yIQ9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:O75718	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2515576|ensembl:ENSP00000323696|uniprotkb:B2RBL6	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:crtap_human(display_long)|uniprotkb:CRTAP(gene name)|psi-mi:CRTAP(display_short)|uniprotkb:CASP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSG00000170275(gene)|ensembl:ENST00000320954(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007283"(spermatogenesis)|go:"GO:0018400"(peptidyl-proline hydroxylation to 3-hydroxy-L-proline)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901874"(negative regulation of post-translational protein modification)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR033212|mint:O75718|reactome:R-HSA-1650814|refseq:NP_006362.1	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:7rtGL+UxGVyDTmnJagIzXaUziIw9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9ULV4	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-351384|uniprotkb:Q9NSK5|uniprotkb:B3KU12|ensembl:ENSP00000261401|ensembl:ENSP00000438341|intact:EBI-4404698|uniprotkb:A7MAP0|uniprotkb:A7MAP1	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:cor1c_human(display_long)|uniprotkb:CORO1C(gene name)|psi-mi:CORO1C(display_short)|uniprotkb:CRNN4(gene name synonym)|uniprotkb:Coronin-3(gene name synonym)|uniprotkb:hCRNN4(gene name synonym)|uniprotkb:CRN2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001263400.1|refseq:NP_055140.1|ensembl:ENSG00000110880(gene)|ensembl:ENST00000261401(transcript)|ensembl:ENST00000541050(transcript)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006909"(phagocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007165"(signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0051015"(actin filament binding)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0090148"(membrane fission)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0016197"(endosomal transport)|go:"GO:0097750"(endosome membrane tubulation)|go:"GO:0140285"(endosome fission)|go:"GO:1900024"(regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900027"(regulation of ruffle assembly)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR001680(WD40 repeat)|interpro:IPR015048(Region of unknown function DUF1899)|interpro:IPR015505(Coronin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR027333|interpro:IPR036322|mint:Q9ULV4|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016600"(flotillin complex)|refseq:NP_001098707.1|refseq:XP_016874610.1|refseq:XP_016874611.1|refseq:XP_016874612.1|dip:DIP-33138N	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:Em/LQxjBk9n4tobk5ksyDfFSyeU9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P27658	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-747133|uniprotkb:Q96D07|uniprotkb:Q53XI6|uniprotkb:D3DN42|ensembl:ENSP00000261037|ensembl:ENSP00000273342|ensembl:ENSP00000498483	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:co8a1_human(display_long)|uniprotkb:Endothelial collagen(gene name synonym)|uniprotkb:COL8A1(gene name)|psi-mi:COL8A1(display_short)|uniprotkb:C3orf7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001841.2|refseq:NP_065084.2|ensembl:ENSG00000144810(gene)|ensembl:ENST00000261037(transcript)|ensembl:ENST00000273342(transcript)|ensembl:ENST00000652472(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005591"(collagen type VIII trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007155"(cell adhesion)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR008983(Tumour necrosis factor-like)|mint:P27658|reactome:R-HSA-1442490|reactome:R-HSA-1650814|reactome:R-HSA-2022090|reactome:R-HSA-216083|reactome:R-HSA-8948216|go:"GO:0030198"(extracellular matrix organization)	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:7doqmNP4HDwd5sPaFgMCUHg4lLA9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q07065	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-702400|uniprotkb:Q504S5|uniprotkb:Q53ES6|ensembl:ENSP00000367265	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:ckap4_human(display_long)|uniprotkb:CKAP4(gene name)|psi-mi:CKAP4(display_short)|uniprotkb:63-kDa cytoskeleton-linking membrane protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_006816.2|ensembl:ENSG00000136026(gene)|ensembl:ENST00000378026(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042599"(lamellar body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028428|mint:Q07065|reactome:R-HSA-381426|reactome:R-HSA-5683826|reactome:R-HSA-6798695|reactome:R-HSA-8957275|reactome:R-HSA-9696264|reactome:R-HSA-9696270	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:Q1hrxqh5k4Myf7J0To8Ecm/xxs49606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P52907	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-355586|uniprotkb:Q53FQ6|uniprotkb:Q6FHD5|ensembl:ENSP00000263168	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:caza1_human(display_long)|uniprotkb:CAPZA1(gene name)|psi-mi:CAPZA1(display_short)|uniprotkb:CapZ alpha-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_006126.1|ensembl:ENSG00000116489(gene)|ensembl:ENST00000263168(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0034329"(cell junction assembly)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071203"(WASH complex)|interpro:IPR002189(F-actin capping protein, alpha subunit)|interpro:IPR017865|interpro:IPR037282|interpro:IPR042276|interpro:IPR042489|mint:P52907|rcsb pdb:1MQ1|rcsb pdb:1MWN|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-879415|reactome:R-HSA-8950505|reactome:R-HSA-9662360|reactome:R-HSA-983231	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:97S4WPtjgt4MDLoptRhQ2yH8UNE9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P59998	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-351872|uniprotkb:O15509|uniprotkb:C9JWM7|uniprotkb:E7ETI0|uniprotkb:Q6P0W5|uniprotkb:Q96QJ3|ensembl:ENSP00000380431|uniprotkb:F6TTL5	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:arpc4_human(display_long)|uniprotkb:ARPC4(gene name)|psi-mi:ARPC4(display_short)|uniprotkb:ARC20(gene name synonym)|uniprotkb:Arp2/3 complex 20 kDa subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001185709.1|refseq:NP_005709.1|ensembl:ENSG00000241553(gene)|ensembl:ENST00000397261(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042995"(cell projection)|go:"GO:0045010"(actin nucleation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008384(ARP23 complex 20 kDa subunit)|interpro:IPR034666|mint:P59998|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|refseq:NP_001020130.1|refseq:NP_001020131.1|dip:DIP-33188N	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:Iqe60TWfO3QBVOY+fOqZd9JWfIE9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q86V81	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-347640|uniprotkb:O43672	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q562R1	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1773495|uniprotkb:Q562R2|uniprotkb:Q562S9|uniprotkb:Q562X8|uniprotkb:B2RPJ1|ensembl:ENSP00000416706	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:actbl_human(display_long)|uniprotkb:ACTBL2(gene name)|psi-mi:ACTBL2(display_short)|uniprotkb:Kappa-actin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26610886|imex:IM-28698-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001017992.1|ensembl:ENSG00000169067(gene)|ensembl:ENST00000423391(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0007409"(axonogenesis)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0045202"(synapse)|go:"GO:0048870"(cell motility)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:Q562R1	-	-	-	figure legend:fig.3c suppl.table 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/08	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:GTzKP5YRJGH8ocAJW0WEsdQFEdc9606	rigid:aqycV7ZenA2h0dIBHfh+GdzDfdY	false	flag tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q5VU43	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1105124|uniprotkb:A2RU15|uniprotkb:O75042|uniprotkb:O75065|uniprotkb:Q5VU42|uniprotkb:Q5VU44|uniprotkb:Q5VU45|uniprotkb:Q5VU46|uniprotkb:Q5VU47|uniprotkb:Q5VU48|uniprotkb:Q5VU49|uniprotkb:Q68DU2|uniprotkb:Q6AZ93|uniprotkb:Q6PK88|uniprotkb:Q86T40|uniprotkb:Q86TB2|uniprotkb:Q8N3W0|uniprotkb:Q8TAY9|uniprotkb:Q9HCP2|uniprotkb:Q9HCP3|uniprotkb:Q9HCP4|uniprotkb:Q9HCP5|uniprotkb:Q2YDC1|uniprotkb:A0A0A0MRM0|ensembl:ENSP00000358360|intact:EBI-11953012|intact:EBI-11051716|uniprotkb:A0A0C4DFQ0|uniprotkb:E9PL24	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:myome_human(display_long)|uniprotkb:PDE4DIP(gene name)|psi-mi:PDE4DIP(display_short)|uniprotkb:CMYA2(gene name synonym)|uniprotkb:KIAA0454(gene name synonym)|uniprotkb:KIAA0477(gene name synonym)|uniprotkb:MMGL(gene name synonym)|uniprotkb:Phosphodiesterase 4D-interacting protein(gene name synonym)|uniprotkb:Cardiomyopathy-associated protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26611049|imex:IM-28698-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSG00000178104(gene)|ensembl:ENST00000313431|ensembl:ENSP00000316434|ensembl:ENST00000369347|ensembl:ENSP00000358353|ensembl:ENST00000369349|ensembl:ENSP00000358355|ensembl:ENST00000369351|ensembl:ENSP00000358357|ensembl:ENSP00000358360|ensembl:ENST00000369356|ensembl:ENSP00000358363|ensembl:ENST00000529945|ensembl:ENSP00000433392|ensembl:ENST00000530472|ensembl:ENSP00000482121|ensembl:ENST00000618462|ensembl:ENSP00000479409|ensembl:ENST00000369354(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0019899"(enzyme binding)|go:"GO:0030016"(myofibril)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0034622"|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR010630(Protein of unknown function DUF1220)|interpro:IPR012943(Spindle associated)|mint:Q5VU43|refseq:NP_001002810.1|refseq:NP_001182189.1|refseq:NP_001182190.1|refseq:NP_071754.3|refseq:NP_001002811.2|refseq:NP_001002812.2|refseq:NP_001185761.2|refseq:NP_001185763.3|refseq:NP_055459.5|refseq:XP_016855361.1|refseq:XP_016855362.1|refseq:XP_016858514.1|refseq:XP_016858515.1|dip:DIP-51263N	-	-	-	figure legend:fig.3d|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:eDnkSq7sbpRyz2lqqLvKDzKXHfQ9606	rigid:Fp1oMcn3pA7DZonTTmCaATZRGEg	false	flag tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5SW79	uniprotkb:Q9NRI5	intact:EBI-1104799|uniprotkb:O75058|uniprotkb:Q5SW77|uniprotkb:Q5SW78|uniprotkb:Q7LGA9|uniprotkb:Q86W31|uniprotkb:Q9UQ08|uniprotkb:Q9UQ09|intact:EBI-2559293|intact:EBI-2554822|ensembl:ENSP00000355500|ensembl:ENSP00000483344	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	psi-mi:ce170_human(display_long)|uniprotkb:CEP170(gene name)|psi-mi:CEP170(display_short)|uniprotkb:FAM68A(gene name synonym)|uniprotkb:KAB(gene name synonym)|uniprotkb:KIAA0470(gene name synonym)|uniprotkb:KARP-1-binding protein(gene name synonym)	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26611055|imex:IM-28698-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001035863.1|refseq:NP_001035864.1|refseq:NP_055627.2|ensembl:ENSG00000143702(gene)|ensembl:ENSG00000276725(gene)|ensembl:ENST00000366542(transcript)|ensembl:ENST00000612450(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0072686"(mitotic spindle)|go:"GO:0120103"(centriolar subdistal appendage)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR026644|interpro:IPR029300|mint:Q5SW79|rcsb pdb:4JON|refseq:XP_016858425.1|dip:DIP-37594N	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	-	-	-	figure legend:fig.3d|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/01	rogid:gEJsUZqeO9zpm94iMzIAUvsUbqc9606	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rigid:wKrKDZplQ2QijxDQXSPtcNwZh4U	false	-	flag tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9UKE5	uniprotkb:Q9NRI5	intact:EBI-1051794|intact:EBI-1762540|uniprotkb:O60298|uniprotkb:Q8WUY7|uniprotkb:Q9UKD8|uniprotkb:Q9UKD9|uniprotkb:Q9UKE0|uniprotkb:Q9UKE1|uniprotkb:Q9UKE2|uniprotkb:Q9UKE3|uniprotkb:Q9UKE4|intact:EBI-1968916|uniprotkb:A8K4U1|uniprotkb:D3DNQ6|uniprotkb:A7E2A3|ensembl:ENSP00000399511	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	psi-mi:tnik_human(display_long)|uniprotkb:TNIK(gene name)|psi-mi:TNIK(display_short)|uniprotkb:KIAA0551(gene name synonym)	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26611061|imex:IM-28698-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001155032.1|refseq:NP_001155033.1|refseq:NP_001155034.1|refseq:NP_001155035.1|refseq:NP_001155036.1|refseq:NP_001155037.1|refseq:NP_001155038.1|refseq:NP_055843.1|dip:DIP-37562N|ensembl:ENSG00000154310(gene)|ensembl:ENST00000436636(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007256"(obsolete activation of JNKK activity)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001180(Citron-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q9UKE5|rcsb pdb:2X7F|rcsb pdb:5AX9|rcsb pdb:5CWZ|rcsb pdb:5D7A|rcsb pdb:6RA5|rcsb pdb:6RA7|reactome:R-HSA-2559580	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	-	-	-	figure legend:fig.3d|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/01	rogid:b+FNQZpz2ZX+wcVH9wuqOgZQ/cE9606	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rigid:L7I1dFU4oNka1+lVJtni1RtIb1Q	false	-	flag tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q4V328	uniprotkb:Q9NRI5	intact:EBI-717919|uniprotkb:A6NL78|uniprotkb:Q3MJ75|uniprotkb:Q4V327|uniprotkb:Q4V330|uniprotkb:Q5HYG1|uniprotkb:Q6N046|uniprotkb:Q96DH8|uniprotkb:Q9NQ43|uniprotkb:Q9ULQ3|ensembl:ENSP00000365606	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	psi-mi:grap1_human(display_long)|uniprotkb:GRIPAP1(gene name)|psi-mi:GRIPAP1(display_short)|uniprotkb:KIAA1167(gene name synonym)	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26611067|imex:IM-28698-35	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064522.3|ensembl:ENSG00000068400(gene)|ensembl:ENST00000376423(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0072562"(blood microparticle)|go:"GO:0098837"(postsynaptic recycling endosome)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098998"(extrinsic component of postsynaptic early endosome membrane)|go:"GO:0099152"(regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0099158"(regulation of recycling endosome localization within postsynapse)|go:"GO:1905244"(regulation of modification of synaptic structure)|interpro:IPR026204|mint:Q4V328|dip:DIP-47299N	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	-	-	-	figure legend:fig.3d|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/01	rogid:iIGfz5XvbexX4taRlMqWYsfAVBo9606	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rigid:abXSfUbe3yla765mc4Mg6+kT4UQ	false	-	flag tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8WXI9	uniprotkb:Q9NRI5	intact:EBI-923440|uniprotkb:Q5VUR2|uniprotkb:Q7LG68|uniprotkb:Q9ULS0|uniprotkb:D3DUZ2|ensembl:ENSP00000357644|ensembl:ENSP00000458280|ensembl:ENSP00000489184	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	psi-mi:p66b_human(display_long)|uniprotkb:GATAD2B(gene name)|psi-mi:GATAD2B(display_short)|uniprotkb:KIAA1150(gene name synonym)|uniprotkb:p66/p68(gene name synonym)|uniprotkb:GATA zinc finger domain-containing protein 2B(gene name synonym)	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26611073|imex:IM-28698-37	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_065750.1|refseq:XP_005245421.1|dip:DIP-36054N|ensembl:ENSG00000143614(gene)|ensembl:ENSG00000261992(gene)|ensembl:ENST00000368655(transcript)|ensembl:ENST00000576342(transcript)|ensembl:ENST00000634544(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR032346|interpro:IPR040386|mint:Q8WXI9|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	-	-	-	figure legend:fig.3d|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/01	rogid:pLKkMcJBBWdyMTf+2axWzvZLKP09606	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rigid:y5hxyFBQU7ShAX103RbHCepM5do	false	-	flag tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9GZM8	uniprotkb:Q9NRI5	intact:EBI-928842|uniprotkb:Q86T80|uniprotkb:Q8TAR7|uniprotkb:Q9UH50|uniprotkb:B3KP93|intact:EBI-2557484|intact:EBI-11041407|uniprotkb:D3DTS0|uniprotkb:J3QT32|ensembl:ENSP00000333982	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	psi-mi:ndel1_human(display_long)|uniprotkb:NDEL1(gene name)|psi-mi:NDEL1(display_short)|uniprotkb:Mitosin-associated protein 1(gene name synonym)|uniprotkb:EOPA(gene name synonym)|uniprotkb:MITAP1(gene name synonym)|uniprotkb:NUDEL(gene name synonym)	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26611079|imex:IM-28698-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_110435.1|refseq:NP_001020750.1|refseq:XP_016880674.1|refseq:XP_016880676.1|dip:DIP-29554N|ensembl:ENSG00000166579(gene)|ensembl:ENST00000334527(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0001764"(neuron migration)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0016477"(cell migration)|go:"GO:0021799"(cerebral cortex radially oriented cell migration)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0031252"(cell leading edge)|go:"GO:0032418"(lysosome localization)|go:"GO:0033157"(regulation of intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043203"(axon hillock)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051642"(centrosome localization)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0060053"(neurofilament cytoskeleton)|go:"GO:0070012"(oligopeptidase activity)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0090724"(central region of growth cone)|go:"GO:1900029"(positive regulation of ruffle assembly)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990138"(neuron projection extension)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033493|interpro:IPR033494|mint:Q9GZM8|rcsb pdb:2V66|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	-	-	-	figure legend:fig.3d|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/01	rogid:AtOowum6Uvuo3WRFXzogoOiDSXk9606	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rigid:fTBt7ZujqIrDp03WErdc35yWR6c	false	-	flag tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NXR1	uniprotkb:Q9NRI5	intact:EBI-941227|uniprotkb:Q49AQ2|ensembl:ENSP00000379642|ensembl:ENSP00000379643|ensembl:ENSP00000488050|ensembl:ENSP00000488199|ensembl:ENSP00000501936|ensembl:ENSP00000502160|ensembl:ENSP00000502354|ensembl:ENSP00000502635	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	psi-mi:nde1_human(display_long)|uniprotkb:NDE1(gene name)|psi-mi:NDE1(display_short)|uniprotkb:NUDE(gene name synonym)	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26611085|imex:IM-28698-43	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137451.1|refseq:NP_060138.1|refseq:XP_016878838.1|refseq:XP_016878845.1|ensembl:ENSG00000072864(gene)|ensembl:ENSG00000275911(gene)|ensembl:ENST00000396354(transcript)|ensembl:ENST00000396355(transcript)|ensembl:ENST00000631844(transcript)|ensembl:ENST00000631923(transcript)|ensembl:ENST00000674554(transcript)|ensembl:ENST00000674888(transcript)|ensembl:ENST00000675926(transcript)|ensembl:ENST00000675951(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0001764"(neuron migration)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051642"(centrosome localization)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|mint:Q9NXR1|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9648025	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	-	-	-	figure legend:fig.3d|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/01	rogid:H769EmQerGWsy6Zud3BBzkAuQw49606	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rigid:BfPoNuD6K/ASoY7RKjm2fzuv2IE	false	-	flag tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P43034	uniprotkb:Q9NRI5	intact:EBI-720620|uniprotkb:Q8WZ88|uniprotkb:Q8WZ89|uniprotkb:B2R7Q7|ensembl:ENSP00000380378|ensembl:ENSP00000501969|ensembl:ENSP00000502031|ensembl:ENSP00000502577|ensembl:ENSP00000502735|ensembl:ENSP00000502843	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	psi-mi:lis1_human(display_long)|uniprotkb:PAF acetylhydrolase 45 kDa subunit(gene name synonym)|uniprotkb:PAF-AH alpha(gene name synonym)|uniprotkb:Lissencephaly-1 protein(gene name synonym)|uniprotkb:PAFAH1B1(gene name)|psi-mi:PAFAH1B1(display_short)|uniprotkb:LIS1(gene name synonym)|uniprotkb:MDCR(gene name synonym)|uniprotkb:PAFAHA(gene name synonym)|uniprotkb:MDS(gene name synonym)	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26611091|imex:IM-28698-45	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000421.1|ensembl:ENSG00000007168(gene)|ensembl:ENST00000397195(transcript)|ensembl:ENST00000675202(transcript)|ensembl:ENST00000675331(transcript)|ensembl:ENST00000675390(transcript)|ensembl:ENST00000676098(transcript)|ensembl:ENST00000676188(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000235"(astral microtubule)|go:"GO:0000776"(kinetochore)|refseq:XP_016880188.1|refseq:XP_016880189.1|refseq:XP_016880190.1|dip:DIP-35691N|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001675"(acrosome assembly)|go:"GO:0001764"(neuron migration)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007097"(nuclear migration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007281"(germ cell development)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007611"(learning or memory)|go:"GO:0008017"(microtubule binding)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008201"(heparin binding)|go:"GO:0008247"(1-alkyl-2-acetylglycerophosphocholine esterase complex)|go:"GO:0009306"(protein secretion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0017145"(stem cell division)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0021540"(corpus callosum morphogenesis)|go:"GO:0021766"(hippocampus development)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031514"(motile cilium)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032420"(stereocilium)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0036035"(osteoclast development)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042249"(establishment of planar polarity of embryonic epithelium)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0045202"(synapse)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046469"(platelet activating factor metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0034452"(dynactin binding)|interpro:IPR017252(Dynein regulator)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037190|mint:P43034|rcsb pdb:7MT1|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9648025|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090102"(cochlea development)|go:"GO:0090176"(microtubule cytoskeleton organization involved in establishment of planar polarity)|go:"GO:0090724"(central region of growth cone)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR015943(WD40/YVTN repeat-like)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	-	-	-	figure legend:fig.3d|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/01	rogid:CgijDhrO703mGYXvJ44BgQJfVgM9606	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rigid:7YnI5++hpYRRW9WzksNtpZX2AWE	false	-	flag tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NRI5	uniprotkb:P06396	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-351506|uniprotkb:Q8WVV7|ensembl:ENSP00000362924|uniprotkb:Q5T0I2|uniprotkb:A8MUD1|uniprotkb:B7Z373|uniprotkb:A2A418|uniprotkb:A8MYN7|uniprotkb:B7Z5V1|uniprotkb:F5H1A8	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:gels_human(display_long)|uniprotkb:GSN(gene name)|psi-mi:GSN(display_short)|uniprotkb:Actin-depolymerizing factor(gene name synonym)|uniprotkb:Brevin(gene name synonym)|uniprotkb:AGEL(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26611097|imex:IM-28698-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_000168.1|refseq:NP_001121134.1|refseq:NP_001121136.1|refseq:NP_001121137.1|refseq:NP_001121138.1|refseq:NP_001121139.1|refseq:NP_937895.1|refseq:XP_011516888.1|refseq:XP_011516889.1|refseq:XP_011516890.1|refseq:XP_011516891.1|refseq:XP_011516892.1|refseq:XP_011516893.1|refseq:XP_011516894.1|refseq:XP_011516895.1|ensembl:ENSG00000148180(gene)|ensembl:ENST00000373818(transcript)|go:"GO:0002102"(podosome)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007417"(central nervous system development)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014891"(striated muscle atrophy)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030478"(actin cap)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031648"(protein destabilization)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0036313"(phosphatidylinositol 3-kinase catalytic subunit binding)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0045010"(actin nucleation)|go:"GO:0045159"(myosin II binding)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051127"(positive regulation of actin nucleation)|go:"GO:0051693"(actin filament capping)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071801"(regulation of podosome assembly)|go:"GO:0072562"(blood microparticle)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0090527"(actin filament reorganization)|go:"GO:0097017"(renal protein absorption)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:1902174"(positive regulation of keratinocyte apoptotic process)|go:"GO:1903903"(regulation of establishment of T cell polarity)|go:"GO:1903906"(regulation of plasma membrane raft polarization)|go:"GO:1903909"(regulation of receptor clustering)|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030004|mint:P06396|rcsb pdb:1C0F|rcsb pdb:1C0G|rcsb pdb:1D4X|rcsb pdb:1DEJ|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1KCQ|rcsb pdb:1MDU|rcsb pdb:1NLV|rcsb pdb:1NM1|rcsb pdb:1NMD|rcsb pdb:1P8X|rcsb pdb:1SOL|rcsb pdb:1T44|rcsb pdb:1YAG|rcsb pdb:1YVN|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FH1|rcsb pdb:2FH2|rcsb pdb:2FH3|rcsb pdb:2FH4|rcsb pdb:3A5L|rcsb pdb:3A5M|rcsb pdb:3A5N|rcsb pdb:3A5O|rcsb pdb:3CI5|rcsb pdb:3CIP|rcsb pdb:3CJB|rcsb pdb:3CJC|rcsb pdb:3FFK|rcsb pdb:3FFN|rcsb pdb:3TU5|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4S10|rcsb pdb:4Z94|rcsb pdb:5DD2|rcsb pdb:5FAE|rcsb pdb:5FAF|rcsb pdb:5H3M|rcsb pdb:5H3N|rcsb pdb:5O2Z|rcsb pdb:5UBO|rcsb pdb:5ZZ0|rcsb pdb:6H1F|rcsb pdb:6JCO|rcsb pdb:6JEG|rcsb pdb:6JEH|rcsb pdb:6LJE|rcsb pdb:6LJF|rcsb pdb:6Q9R|rcsb pdb:6Q9Z|rcsb pdb:6QBF|rcsb pdb:1P8Z|rcsb pdb:6QW3|reactome:R-HSA-264870|reactome:R-HSA-6798695|reactome:R-HSA-9662361|reactome:R-HSA-977225|refseq:NP_001244958.1|refseq:NP_001244959.1|refseq:NP_001121135.2|refseq:XP_005252000.1|refseq:XP_005252001.1|refseq:XP_005252002.1|refseq:XP_006717142.1|refseq:XP_016870135.1|refseq:XP_016870136.1|refseq:XP_016870137.1|dip:DIP-2196N	-	-	-	figure legend:fig.3d|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-astrocyte)|taxid:9606(Homo sapiens astrocyte)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:uACf9A+H6LAOAZSMGYqeDwUL1Mc9606	rigid:IrU1gQfSZJ1+sBAV0AoMoeMyOtw	false	flag tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NRI5	uniprotkb:Q6PB66	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1371262|uniprotkb:Q8K4V0|uniprotkb:Q9CRX4|ensembl:ENSMUSP00000107927	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:lpprc_mouse(display_long)|uniprotkb:Lrpprc(gene name)|psi-mi:Lrpprc(display_short)|uniprotkb:Lrp130(gene name synonym)|uniprotkb:130 kDa leucine-rich protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_082509.2|ensembl:ENSMUSG00000024120(gene)|ensembl:ENSMUST00000112308(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000961"(negative regulation of mitochondrial RNA catabolic process)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|reactome:R-MMU-611105|reactome:R-MMU-9707564|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR033443|interpro:IPR033490|mint:Q6PB66|reactome:R-MMU-5628897|go:"GO:0005634"(nucleus)	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:wNo59nF0OqIHfnoUrxN10z7YIGM10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q3UDK1	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1396948|uniprotkb:Q8CFI8|ensembl:ENSMUSP00000047475	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:trad1_mouse(display_long)|uniprotkb:Protein FLN29(gene name synonym)|uniprotkb:Trafd1(gene name)|psi-mi:Trafd1(display_short)|uniprotkb:Fln29(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001156942.1|refseq:NP_758479.2|refseq:XP_011246499.1|refseq:XP_006530365.1|refseq:XP_017176353.1|refseq:XP_017176354.1|refseq:XP_017176355.1|ensembl:ENSMUSG00000042726(gene)|ensembl:ENSMUST00000042312(transcript)|go:"GO:0008270"(zinc ion binding)|go:"GO:0045824"(negative regulation of innate immune response)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q3UDK1	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:uiqswqWKIeu+cpTvA7jSw/4YwdI10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q8BFY9	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-3870049|uniprotkb:Q8C0S3|uniprotkb:Q8K2E7|ensembl:ENSMUSP00000105028	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:tnpo1_mouse(display_long)|uniprotkb:Tnpo1(gene name)|psi-mi:Tnpo1(display_short)|uniprotkb:Kpnb2(gene name synonym)|uniprotkb:Importin beta-2(gene name synonym)|uniprotkb:Karyopherin beta-2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001041732.1|refseq:NP_848831.2|refseq:XP_006517699.1|refseq:XP_006517700.1|ensembl:ENSMUSG00000009470(gene)|ensembl:ENSMUST00000109401(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040122|mint:Q8BFY9|reactome:R-MMU-450513|reactome:R-MMU-5620924	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:khDQjW/eY+ga9LRUpgOrxbKi6lg10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q3U319	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-8440451|uniprotkb:Q8CHX4|uniprotkb:Q8BY03|uniprotkb:Q8BJA1|intact:MINT-4110865|uniprotkb:Q6ZQ75|ensembl:ENSMUSP00000146310	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:bre1b_mouse(display_long)|uniprotkb:Rnf40(gene name)|psi-mi:Rnf40(display_short)|uniprotkb:Bre1b(gene name synonym)|uniprotkb:Kiaa0661(gene name synonym)|uniprotkb:RING finger protein 40(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BRE1B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_758485.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013956(E3 ubiquitin ligase, BRE1)|interpro:IPR017907|mint:Q3U319|reactome:R-MMU-8866654|ensembl:ENSMUSG00000030816(gene)|ensembl:ENSMUST00000205694(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033503"(HULC complex)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)	-	-	function:E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-120' of histone H2B. H2B 'Lys-120' ubiquitination gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation. Forms a ubiquitin ligase complex in cooperation with the E2 enzyme UBE2E1/UBCH6. It thereby plays a central role in histone code and gene regulation. Required for transcriptional activation of Hox genes|comment:mint	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:sF6/LJ1K81T6H3WvcDC7RrtEg1c10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q5DTM8	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-8322402|uniprotkb:Q8BKA8|uniprotkb:Q3V350|uniprotkb:Q3UT10|uniprotkb:Q8BUF7|uniprotkb:Q8BKN8|uniprotkb:A2AIR3|intact:MINT-4112835|uniprotkb:Q7TT11|uniprotkb:Q8BVU4|ensembl:ENSMUSP00000029989|ensembl:ENSMUSP00000128546	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:bre1a_mouse(display_long)|uniprotkb:Rnf20(gene name)|psi-mi:Rnf20(display_short)|uniprotkb:Bre1a(gene name synonym)|uniprotkb:Kiaa4116(gene name synonym)|uniprotkb:RING finger protein 20(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BRE1A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:XP_011248208.1|refseq:NP_892044.1|refseq:NP_001156735.1|refseq:XP_006537616.1|ensembl:ENSMUSG00000028309(gene)|ensembl:ENSMUST00000029989(transcript)|ensembl:ENSMUST00000167496(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033503"(HULC complex)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013956(E3 ubiquitin ligase, BRE1)|interpro:IPR017907|mint:Q5DTM8|reactome:R-MMU-8866654|reactome:R-MMU-9013422	-	-	function:E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-120' of histone H2B. H2B 'Lys-120' ubiquitination gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation. Forms a ubiquitin ligase complex in cooperation with the E2 enzyme UBE2E1/UBCH6. It thereby plays a central role in histone code and gene regulation. Required for transcriptional activation of Hox genes. Recruited to the MDM2 promoter, probably by being recruited by p53/TP53, and thereby acts as a transcriptional coactivator|comment:mint	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:PhsdSpbqYBrj8HpxLgEC0nVBwd810090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P62715	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-8028975|uniprotkb:P11082|intact:UNK-5382027|ensembl:ENSMUSP00000009774	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:pp2ab_mouse(display_long)|uniprotkb:Ppp2cb(gene name)|psi-mi:Ppp2cb(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_059070.1|ensembl:ENSMUSG00000009630(gene)|ensembl:ENSMUST00000009774(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P62715|reactome:R-MMU-113501|reactome:R-MMU-1295596|reactome:R-MMU-141444|reactome:R-MMU-180024|reactome:R-MMU-195253|reactome:R-MMU-196299|reactome:R-MMU-198753|reactome:R-MMU-202670|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-389513|reactome:R-MMU-432142|reactome:R-MMU-4641262|reactome:R-MMU-5663220|reactome:R-MMU-5673000|reactome:R-MMU-5675221|reactome:R-MMU-6804757|reactome:R-MMU-6811558|reactome:R-MMU-68877|reactome:R-MMU-69231|reactome:R-MMU-69273|reactome:R-MMU-9648025	-	-	function:PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase|comment:mint|comment:homomint	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q63850	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-8341160|uniprotkb:Q99JN7|intact:MINT-4104316|ensembl:ENSMUSP00000056785|ensembl:ENSMUSP00000146695|ensembl:ENSMUSP00000147181	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:nup62_mouse(display_long)|uniprotkb:Nup62(gene name)|psi-mi:Nup62(display_short)|uniprotkb:62 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup62(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_444304.1|ensembl:ENSMUSG00000109511(gene)|ensembl:ENSMUST00000057195(transcript)|ensembl:ENSMUST00000207103(transcript)|ensembl:ENSMUST00000208626(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007569"(cell aging)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016477"(cell migration)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051425"(PTB domain binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090543"(Flemming body)|go:"GO:0098534"(centriole assembly)|go:"GO:1903438"(positive regulation of mitotic cytokinetic process)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007758(Nucleoporin, Nsp1-like, C-terminal)|interpro:IPR026010|interpro:IPR033072|mint:Q63850|reactome:R-MMU-159227|reactome:R-MMU-159230|reactome:R-MMU-159231|reactome:R-MMU-159236|reactome:R-MMU-170822|reactome:R-MMU-191859|reactome:R-MMU-3108214|reactome:R-MMU-3232142|reactome:R-MMU-3301854|reactome:R-MMU-3371453|reactome:R-MMU-4085377|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-4615885|reactome:R-MMU-5578749	-	-	function:Essential component of the nuclear pore complex. The N-terminal is probably involved in nucleocytoplasmic transport. The C-terminal is probably involved in protein-protein interaction via coiled-coil formation and may function in anchorage of p62 to the pore complex|comment:mint	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:jmxg6bqf4YwOBAPsEsvBHk2YZJ410090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q8R0G9	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-8372895|uniprotkb:E9QLJ8|intact:MINT-4104201|ensembl:ENSMUSP00000048084	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:nu133_mouse(display_long)|uniprotkb:Nup133(gene name)|psi-mi:Nup133(display_short)|uniprotkb:Nucleoporin Nup133(gene name synonym)|uniprotkb:133 kDa nucleoporin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_758492.2|ensembl:ENSMUSG00000039509(gene)|ensembl:ENSMUST00000044795(transcript)|go:"GO:0000940"(outer kinetochore)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005643"(nuclear pore)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0021915"(neural tube development)|go:"GO:0022008"(neurogenesis)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0061053"(somite development)|go:"GO:0072006"(nephron development)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037624|mint:Q8R0G9|reactome:R-MMU-141444|reactome:R-MMU-159227|reactome:R-MMU-159230|reactome:R-MMU-159231|reactome:R-MMU-159236|reactome:R-MMU-170822|reactome:R-MMU-191859|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3108214|reactome:R-MMU-3232142|reactome:R-MMU-3301854|reactome:R-MMU-3371453|reactome:R-MMU-4085377|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-4615885|reactome:R-MMU-5578749|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-9615933|reactome:R-MMU-9648025	-	-	comment:mint|function:"Involved in poly(A)+ RNA transport"	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:pYvSVvYRH+TCeinxLZL8Lmwd5OM10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q91X76	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-8440005|intact:MINT-4121664|ensembl:ENSMUSP00000087680	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:q91x76_mouse(display_long)|uniprotkb:Nt5dc2(gene name)|psi-mi:Nt5dc2(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_081565.1|ensembl:ENSMUSG00000071547(gene)|ensembl:ENSMUST00000090212(transcript)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR008380(HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase)|interpro:IPR016695(Purine 5'-nucleotidase)|interpro:IPR023214|interpro:IPR036412|mint:Q91X76	-	-	comment:mint	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:ba3L+gtyiqBaAWNphSVt+/b1N8A10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P02468	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-7059830|intact:MINT-1031545	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:lamc1_mouse(display_long)|uniprotkb:Lamc1(gene name)|psi-mi:Lamc1(display_short)|uniprotkb:Lamb-2(gene name synonym)|uniprotkb:Lamc-1(gene name synonym)|uniprotkb:Laminin B2 chain(gene name synonym)|uniprotkb:Laminin-1 subunit gamma(gene name synonym)|uniprotkb:Laminin-2 subunit gamma(gene name synonym)|uniprotkb:Laminin-3 subunit gamma(gene name synonym)|uniprotkb:Laminin-4 subunit gamma(gene name synonym)|uniprotkb:Laminin-6 subunit gamma(gene name synonym)|uniprotkb:Laminin-7 subunit gamma(gene name synonym)|uniprotkb:Laminin-8 subunit gamma(gene name synonym)|uniprotkb:Laminin-9 subunit gamma(gene name synonym)|uniprotkb:Laminin-10 subunit gamma(gene name synonym)|uniprotkb:Laminin-11 subunit gamma(gene name synonym)|uniprotkb:S-laminin subunit gamma(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	mint:P02468|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005606"(laminin-1 complex)|go:"GO:0007155"(cell adhesion)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016477"(cell migration)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031175"(neuron projection development)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043208"(glycosphingolipid binding)|go:"GO:0043259"(laminin-10 complex)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000034(Laminin B)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|rcsb pdb:1KLO|rcsb pdb:1NPE|rcsb pdb:1TLE|rcsb pdb:4AQT|rcsb pdb:5MC9|reactome:R-MMU-3000157|reactome:R-MMU-381426|reactome:R-MMU-8957275|reactome:R-MMU-8874081|dip:DIP-41793N	-	-	comment:mint|function:Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:LTc4oIJUjQ8INjkodiPpXvL/rx010090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q8VD04	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-7585099|uniprotkb:A2AEW7|uniprotkb:O35693|uniprotkb:Q69ZP9|uniprotkb:Q3T9C3|intact:MINT-4609304|ensembl:ENSMUSP00000068789	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:grap1_mouse(display_long)|uniprotkb:Gripap1(gene name)|psi-mi:Gripap1(display_short)|uniprotkb:DXImx47e(gene name synonym)|uniprotkb:Kiaa1167(gene name synonym)|uniprotkb:HCMV-interacting protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_997553.1|ensembl:ENSMUSG00000031153(gene)|ensembl:ENSMUST00000065932(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0098837"(postsynaptic recycling endosome)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098998"(extrinsic component of postsynaptic early endosome membrane)|go:"GO:0099152"(regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0099158"(regulation of recycling endosome localization within postsynapse)|go:"GO:1905244"(regulation of modification of synaptic structure)|interpro:IPR026204|mint:Q8VD04	-	-	comment:mint	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:if5RPMbiuuu/rqXtkhbJg8X0Z2w10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9D187	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-8313588|ensembl:ENSMUSP00000132725|intact:MINT-4090711	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:cia2b_mouse(display_long)|uniprotkb:Ciao2b(gene name)|psi-mi:Ciao2b(display_short)|uniprotkb:Fam96b(gene name synonym)|uniprotkb:Mip18(gene name synonym)|uniprotkb:Mitotic spindle-associated MMXD complex subunit MIP18(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|interpro:IPR002744(Protein of unknown function DUF59)|interpro:IPR034904|interpro:IPR039796|mint:Q9D187|ensembl:ENSMUSG00000031879(gene)|ensembl:ENSMUST00000164884(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|refseq:NP_081029.1	-	-	comment:mint	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:psvL+/Ix2gmnR4ziLNfUG+uWqx810090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q3TZZ7	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-8399840|uniprotkb:Q9D5Y7|uniprotkb:B2RSN5|intact:MINT-4392453|ensembl:ENSMUSP00000098548|ensembl:ENSMUSP00000152444	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:esyt2_mouse(display_long)|uniprotkb:D12Ertd551e(gene name synonym)|uniprotkb:Esyt2(gene name)|psi-mi:Esyt2(display_short)|uniprotkb:Fam62b(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_083007.2|refseq:XP_017170617.1|ensembl:ENSMUSG00000021171(gene)|ensembl:ENSMUST00000100986(transcript)|ensembl:ENSMUST00000220816(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0140268"(endoplasmic reticulum-plasma membrane contact site)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037733|interpro:IPR037749|interpro:IPR037752|interpro:IPR039010|mint:Q3TZZ7|reactome:R-MMU-1660662|go:"GO:0031210"(phosphatidylcholine binding)	-	-	function:May play a role as calcium-regulated intrinsic membrane protein|comment:mint	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:ABzmuYWwkEH2ViBYbUHGfhZEf3g10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:O08811	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-8458063|intact:MINT-4114299|uniprotkb:Q9DC01|uniprotkb:Q8C487|ensembl:ENSMUSP00000054380	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:ercc2_mouse(display_long)|uniprotkb:Ercc2(gene name)|psi-mi:Ercc2(display_short)|uniprotkb:CXPD(gene name synonym)|uniprotkb:DNA excision repair protein ERCC-2(gene name synonym)|uniprotkb:DNA repair protein complementing XP-D cells(gene name synonym)|uniprotkb:Xeroderma pigmentosum group D-complementing protein(gene name synonym)|uniprotkb:Xpd(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_031975.2|ensembl:ENSMUSG00000030400(gene)|ensembl:ENSMUST00000062831(transcript)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000717"(nucleotide-excision repair, DNA duplex unwinding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007568"(aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009411"(response to UV)|go:"GO:0009650"(UV protection)|go:"GO:0009791"(post-embryonic development)|go:"GO:0021510"(spinal cord development)|go:"GO:0022405"(hair cycle process)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030282"(bone mineralization)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032289"(central nervous system myelin formation)|go:"GO:0033683"(nucleotide-excision repair, DNA incision)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043588"(skin development)|go:"GO:0045951"(positive regulation of mitotic recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070516"(CAK-ERCC2 complex)|go:"GO:0071817"(MMXD complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|interpro:IPR001945(Xeroderma pigmentosum group D protein)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR006554(Helicase-like, DEXD box c2 type)|interpro:IPR006555(Helicase, ATP-dependent, c2 type)|interpro:IPR010614(DEAD2)|interpro:IPR010643(Protein of unknown function DUF1227)|interpro:IPR013020("DNA helicase (DNA repair), Rad3 type")|interpro:IPR014013(Helicase, superfamily 1 and 2, ATP-binding, DinG/Rad3-type)|interpro:IPR027417|mint:O08811|reactome:R-MMU-112382|reactome:R-MMU-113418|reactome:R-MMU-5696395|reactome:R-MMU-5696400|reactome:R-MMU-674695|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6796648|reactome:R-MMU-72086|reactome:R-MMU-73762|reactome:R-MMU-73772|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-73863|reactome:R-MMU-75953|reactome:R-MMU-75955|reactome:R-MMU-76042|reactome:R-MMU-77075	-	-	comment:mint	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:pZ0AswL2zMKRhVFY+Vp5TxdR1fA10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P61963	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-8318793|uniprotkb:Q9DAE4|uniprotkb:Q3TMV9|uniprotkb:O15491|intact:MINT-4428227|ensembl:ENSMUSP00000058168	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:dcaf7_mouse(display_long)|uniprotkb:Dcaf7(gene name)|psi-mi:Dcaf7(display_short)|uniprotkb:Han11(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:Wdr68(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_082222.1|ensembl:ENSMUSG00000049354(gene)|ensembl:ENSMUST00000058438(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61963|reactome:R-MMU-8951664	-	-	comment:mint	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:wDucyMrZBaqRcL25mMGhB4KXQtI10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9JIG7	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-8311726|ensembl:ENSMUSP00000033483|intact:MINT-1865494|uniprotkb:Q8BYH4|uniprotkb:B1AVA1	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:ccd22_mouse(display_long)|uniprotkb:Ccdc22(gene name)|psi-mi:Ccdc22(display_short)|uniprotkb:DXImx40e(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000031143(gene)|ensembl:ENSMUST00000033483(transcript)|go:"GO:0005768"(endosome)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097006"(regulation of plasma lipoprotein particle levels)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|mint:Q9JIG7|reactome:R-MMU-8951664|refseq:NP_613069.3	-	-	comment:mint	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:gmVzezOv+1Rb/3mGcUEltJJq8lA10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9D287	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-8338824|uniprotkb:Q91YX8|intact:MINT-4126699|uniprotkb:Q9DAI0|uniprotkb:Q3TKJ5|uniprotkb:Q9D2U4|ensembl:ENSMUSP00000005830	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:spf27_mouse(display_long)|uniprotkb:Bcas2(gene name)|psi-mi:Bcas2(display_short)|uniprotkb:Dam1(gene name synonym)|uniprotkb:Breast carcinoma-amplified sequence 2 homolog(gene name synonym)|uniprotkb:DNA amplified in mammary carcinoma 1 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_080878.2|ensembl:ENSMUSG00000005687(gene)|ensembl:ENSMUST00000005830(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005813"(centrosome)|go:"GO:0016607"(nuclear speck)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR008409(Breast carcinoma amplified sequence 2)|mint:Q9D287|reactome:R-MMU-72163	-	-	comment:mint	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:yBhnwZOlEWsxnRIeuf/Z85O/QSQ10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q8C103	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-8393653|intact:MINT-4113920	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:q8c103_mouse(display_long)|uniprotkb:Ankhd1(gene name)|psi-mi:Ankhd1(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	interpro:IPR020683|refseq:NP_780584.2|interpro:IPR036770|mint:Q8C103|go:"GO:0005737"(cytoplasm)|go:"GO:0045087"(innate immune response)|interpro:IPR002110(Ankyrin)	-	-	comment:"fragmentation type: fragment"|comment:mint	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:7dxkzG95vtHdfZGWbCUH3ej6zAE10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:O54692	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2553168|ensembl:ENSMUSP00000034803|uniprotkb:Q3TIA5|uniprotkb:Q3ULW1|uniprotkb:Q921H3	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:zw10_mouse(display_long)|uniprotkb:Zw10(gene name)|psi-mi:Zw10(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	go:"GO:0015031"(protein transport)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0070939"(Dsl1/NZR complex)|go:"GO:1990423"(RZZ complex)|interpro:IPR009361(Centromerekinetochore Zw10)|mint:O54692|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-5663220|reactome:R-MMU-6811434|reactome:R-MMU-68877|reactome:R-MMU-9648025|ensembl:ENSMUST00000034803(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|ensembl:ENSMUSG00000032264(gene)|refseq:NP_036169.1	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:NyiaWyimluVe+0RJZA61CWlAlho10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P62259	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-356480|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q63631|ensembl:ENSMUSP00000070993	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:1433e_mouse(display_long)|uniprotkb:Ywhae(gene name)|psi-mi:Ywhae(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000020849(gene)|ensembl:ENSMUST00000067664(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001764"(neuron migration)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0006605"(protein targeting)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|refseq:NP_033562.3|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62259|reactome:R-MMU-111447|reactome:R-MMU-2028269|reactome:R-MMU-205025|reactome:R-MMU-2565942|reactome:R-MMU-3371453|reactome:R-MMU-3371511|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-75035|reactome:R-MMU-8854518|reactome:R-MMU-8876198	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:O88967	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-11518380|uniprotkb:Q7TNN5|ensembl:ENSMUSP00000028117	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:ymel1_mouse(display_long)|uniprotkb:ATP-dependent metalloprotease FtsH1(gene name synonym)|uniprotkb:YME1-like protein 1(gene name synonym)|uniprotkb:Yme1l1(gene name)|psi-mi:Yme1l1(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_038799.1|ensembl:ENSMUSG00000026775(gene)|ensembl:ENSMUST00000028117(transcript)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0034214"(protein hexamerization)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0035694"(mitochondrial protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000642(Peptidase M41)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005936(Peptidase M41, FtsH)|interpro:IPR027417|interpro:IPR037219|interpro:IPR041569|mint:O88967|reactome:R-MMU-8949664|go:"GO:0007005"(mitochondrion organization)	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:r9+ZzXnqp1squdeZ4KAr6YVU29c10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9CRT8	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-644629|uniprotkb:Q52KI1|ensembl:ENSMUSP00000043488	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:xpot_mouse(display_long)|uniprotkb:tRNA exportin(gene name synonym)|uniprotkb:"Exportin(tRNA)"(gene name synonym)|uniprotkb:Xpot(gene name)|psi-mi:Xpot(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000034667(gene)|ensembl:ENSMUST00000039810(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031267"(small GTPase binding)|go:"GO:0071528"(tRNA re-export from nucleus)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040017|mint:Q9CRT8	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:sxoS4tNMBaRRDwVJM5HlK1c2avE10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q924C1	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-6907785|ensembl:ENSMUSP00000084257|uniprotkb:A2RRJ5|uniprotkb:Q7TMP2|uniprotkb:Q80TF9|uniprotkb:Q9CRI9|uniprotkb:Q9CT48	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:xpo5_mouse(display_long)|uniprotkb:Xpo5(gene name)|psi-mi:Xpo5(display_short)|uniprotkb:Kiaa1291(gene name synonym)|uniprotkb:Ranbp21(gene name synonym)|uniprotkb:Ran-binding protein 21(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000067150(gene)|ensembl:ENSMUST00000087031(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016442"(RISC complex)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:1900370"(positive regulation of RNA interference)|go:"GO:1905172"(RISC complex binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040018|mint:Q924C1|refseq:NP_082474.1	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:npbBFtlUZCx9pnmtdFLQ4qODLzU10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q99J09	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2940098|ensembl:ENSMUSP00000010278|uniprotkb:Q3TFJ1|uniprotkb:Q8BSH8|uniprotkb:Q9CZY5	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:mep50_mouse(display_long)|uniprotkb:Wdr77(gene name)|psi-mi:Wdr77(display_short)|uniprotkb:Mep50(gene name synonym)|uniprotkb:WD repeat-containing protein 77(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000000561(gene)|ensembl:ENSMUST00000010278(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0034709"(methylosome)|go:"GO:0045495"(pole plasm)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:Q99J09|reactome:R-MMU-191859|reactome:R-MMU-3214858|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|refseq:NP_081708.1	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:JFY7nRR7e+fM7CD6/0A/oqvC1xU10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q3U3T8	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2365469|uniprotkb:Q6PGG0|uniprotkb:Q7TQE9	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:wdr62_mouse(display_long)|uniprotkb:Wdr62(gene name)|psi-mi:Wdr62(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR024977|mint:Q3U3T8|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007099"(centriole replication)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022008"(neurogenesis)|go:"GO:0034451"(centriolar satellite)|go:"GO:0097150"(neuronal stem cell population maintenance)	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:l1ykYPJWylrUCk6FY/w9DHoAZz810090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P70398	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2214043|uniprotkb:E9QLY0|uniprotkb:Q62497	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:usp9x_mouse(display_long)|uniprotkb:Ubiquitin thioesterase FAF-X(gene name synonym)|uniprotkb:Usp9x(gene name)|psi-mi:Usp9x(display_short)|uniprotkb:Fafl(gene name synonym)|uniprotkb:Fam(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease FAF-X(gene name synonym)|uniprotkb:Deubiquitinating enzyme FAF-X(gene name synonym)|uniprotkb:Fat facets protein-related, X-linked(gene name synonym)|uniprotkb:Ubiquitin-specific protease 9, X chromosome(gene name synonym)|uniprotkb:Ubiquitin carboxyl-terminal hydrolase FAM(gene name synonym)|uniprotkb:Fat facets homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	interpro:IPR016024(Armadillo-type fold)|interpro:IPR028889|refseq:NP_033507.2|interpro:IPR018200|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|mint:P70398|interpro:IPR038765|interpro:IPR021905|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001764"(neuron migration)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016477"(cell migration)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021698"(cerebellar cortex structural organization)|go:"GO:0021766"(hippocampus development)|go:"GO:0030426"(growth cone)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045177"(apical part of cell)|go:"GO:0048511"(rhythmic process)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071947"(protein deubiquitination involved in ubiquitin-dependent protein catabolic process)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|reactome:R-MMU-2173795|reactome:R-MMU-5689880|reactome:R-MMU-8866652|reactome:R-MMU-9013420|reactome:R-MMU-9013424|reactome:R-MMU-9033241	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:QXx5gkd+PxoNgIj2b2dLjpCuNr410090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q80TP3	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2553642|uniprotkb:Q810V6|uniprotkb:Q698K9|uniprotkb:Q9CXE9|uniprotkb:Q6PFQ9|uniprotkb:Q80VL4|uniprotkb:Q6PEQ8	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:ubr5_mouse(display_long)|uniprotkb:Ubr5(gene name)|psi-mi:Ubr5(display_short)|uniprotkb:Edd(gene name synonym)|uniprotkb:Edd1(gene name synonym)|uniprotkb:Kiaa0896(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase, HECT domain-containing 1(gene name synonym)|uniprotkb:Hyperplastic discs protein homolog(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase UBR5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR000569(HECT)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR024725|interpro:IPR035983|interpro:IPR036053|go:"GO:0061630"(ubiquitin protein ligase activity)|refseq:NP_001074828.2|refseq:NP_001106192.1|dip:DIP-56890N|mint:Q80TP3	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:iUtn1CtWFtqWQV3UH06xJ5R5Ux010090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P62984	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2311646|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62991|uniprotkb:Q29120|uniprotkb:Q62317|uniprotkb:Q64223|uniprotkb:Q8VCH1|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9CXY4|uniprotkb:Q9CZM0|uniprotkb:Q9D1R5|uniprotkb:Q9D8D9|uniprotkb:Q9ET23|uniprotkb:Q9ET24|uniprotkb:Q9Z0H9|ensembl:ENSMUSP00000080608|ensembl:ENSMUSP00000121149|ensembl:ENSMUSP00000123263|ensembl:ENSMUSP00000123562|ensembl:ENSMUSP00000137461|ensembl:ENSMUSP00000086852|ensembl:ENSMUSP00000120096	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:rl40_mouse(display_long)|uniprotkb:Uba52(gene name)|psi-mi:Uba52(display_short)|uniprotkb:Ubcep2(gene name synonym)|uniprotkb:Ubiquitin A-52 residue ribosomal protein fusion product 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	uniprotkb:Q66JP1(uniprot-removed-ac)|refseq:NP_001335156.1|refseq:NP_001335157.1|refseq:NP_001335158.1|refseq:NP_063936.1|ensembl:ENSMUSG00000068240(gene)|ensembl:ENSMUSG00000090137(gene)|ensembl:ENSMUST00000081940(transcript)|ensembl:ENSMUST00000125184(transcript)|ensembl:ENSMUST00000129909(transcript)|ensembl:ENSMUST00000135446(transcript)|ensembl:ENSMUST00000140679(transcript)|ensembl:ENSMUST00000165126(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045202"(synapse)|interpro:IPR000626(Ubiquitin)|interpro:IPR001975(Ribosomal protein L40e)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038587|mint:P62984|rcsb pdb:3AI5|rcsb pdb:6JWI|rcsb pdb:6SWA|reactome:R-MMU-110312|reactome:R-MMU-110314|reactome:R-MMU-110320|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1253288|reactome:R-MMU-1295596|reactome:R-MMU-1358803|reactome:R-MMU-156827|reactome:R-MMU-168638|reactome:R-MMU-174048|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-179409|reactome:R-MMU-1799339|reactome:R-MMU-182971|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-201681|reactome:R-MMU-202424|reactome:R-MMU-205043|reactome:R-MMU-209543|reactome:R-MMU-209560|reactome:R-MMU-2122948|reactome:R-MMU-2173788|reactome:R-MMU-2173791|reactome:R-MMU-2173795|reactome:R-MMU-2173796|reactome:R-MMU-2467813|reactome:R-MMU-2559580|reactome:R-MMU-2559582|reactome:R-MMU-2559585|reactome:R-MMU-2565942|reactome:R-MMU-2672351|ensembl:ENSMUST00000089430(transcript)|reactome:R-MMU-2871837|reactome:R-MMU-3134975|reactome:R-MMU-349425|reactome:R-MMU-3769402|reactome:R-MMU-382556|reactome:R-MMU-445989|reactome:R-MMU-450302|reactome:R-MMU-450321|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-4641263|reactome:R-MMU-532668|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5654726|reactome:R-MMU-5654727|reactome:R-MMU-5654732|reactome:R-MMU-5654733|reactome:R-MMU-5655862|reactome:R-MMU-5656121|reactome:R-MMU-5656169|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5675221|reactome:R-MMU-5675482|reactome:R-MMU-5676590|reactome:R-MMU-5684264|reactome:R-MMU-5685942|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689877|reactome:R-MMU-5689880|reactome:R-MMU-5689896|reactome:R-MMU-5689901|reactome:R-MMU-5693565|reactome:R-MMU-5696394|reactome:R-MMU-5696395|reactome:R-MMU-5696397|reactome:R-MMU-5696400|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6783310|reactome:R-MMU-6791226|reactome:R-MMU-6804756|reactome:R-MMU-6804757|reactome:R-MMU-6804760|reactome:R-MMU-6807004|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69231|reactome:R-MMU-69481|reactome:R-MMU-69541|reactome:R-MMU-69601|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-75815|reactome:R-MMU-8849469|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8863795|reactome:R-MMU-8866652|reactome:R-MMU-8866654|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948747|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-901032|reactome:R-MMU-9010553|reactome:R-MMU-9013507|reactome:R-MMU-9020702|reactome:R-MMU-9033241|reactome:R-MMU-912631|reactome:R-MMU-917729|reactome:R-MMU-917937|reactome:R-MMU-936440|reactome:R-MMU-936964|reactome:R-MMU-937039|reactome:R-MMU-937041|reactome:R-MMU-937042|reactome:R-MMU-937072|reactome:R-MMU-9645460|reactome:R-MMU-9646399|reactome:R-MMU-9648002|reactome:R-MMU-9664873|reactome:R-MMU-9705462|reactome:R-MMU-9706369|reactome:R-MMU-9708530|reactome:R-MMU-975144|reactome:R-MMU-975163|reactome:R-MMU-975956|reactome:R-MMU-975957|reactome:R-MMU-983168	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:x9O/Pbww4D28M1+hIj+p0xrUXgU10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9CWF2	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2794256|uniprotkb:Q3TG26|ensembl:ENSMUSP00000075178	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:tbb2b_mouse(display_long)|uniprotkb:Tubb2b(gene name)|psi-mi:Tubb2b(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_076205.1|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:1902669"(positive regulation of axon guidance)|go:"GO:1990403"(embryonic brain development)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9CWF2|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|ensembl:ENSMUSG00000045136(gene)|ensembl:ENSMUST00000075774(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0046982"(protein heterodimerization activity)	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:sluQMryNuOvp6xlV558+agiRwvE10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q7TMM9	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2255578|ensembl:ENSMUSP00000060246	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:tbb2a_mouse(display_long)|uniprotkb:Tubb2(gene name synonym)|uniprotkb:Tubb2a(gene name)|psi-mi:Tubb2a(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_033476.1|ensembl:ENSMUSG00000058672(gene)|ensembl:ENSMUST00000056427(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q7TMM9|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:XN9uTGU0KxQjMod0AGnM+XJoHyk10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q6ZQC8	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-26611701	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:q6zqc8_mouse(display_long)|uniprotkb:Ttc37(gene name)|psi-mi:Ttc37(display_short)|uniprotkb:AK129128(gene name synonym)|uniprotkb:mKIAA0372(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0035327"|go:"GO:0055087"(Ski complex)|mint:Q6ZQC8|interpro:IPR039226|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:GnjhgSg3Zkve6kEEtdzeAO8so+I10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q8CD92	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-26611684|ensembl:ENSMUSP00000024882|uniprotkb:Q3THU0|uniprotkb:Q8C7S8|uniprotkb:Q8K1D9	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:ttc27_mouse(display_long)|uniprotkb:Ttc27(gene name)|psi-mi:Ttc27(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUST00000024882(transcript)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR044244|mint:Q8CD92|ensembl:ENSMUSG00000024078(gene)|refseq:NP_690030.3|refseq:XP_006525088.1	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:ezL3nkmUhcjNksSHIlHt1GkRx6c10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q8CG48	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-643436|uniprotkb:Q52KE9|uniprotkb:Q61076|uniprotkb:Q9CS17|uniprotkb:Q9CSD8|ensembl:ENSMUSP00000099979|ensembl:ENSMUSP00000113940	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:smc2_mouse(display_long)|uniprotkb:Chromosome-associated protein E(gene name synonym)|uniprotkb:XCAP-E homolog(gene name synonym)|uniprotkb:FGF-inducible protein 16(gene name synonym)|uniprotkb:Smc2(gene name)|psi-mi:Smc2(display_short)|uniprotkb:Cape(gene name synonym)|uniprotkb:Fin16(gene name synonym)|uniprotkb:Smc2l1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_032043.3|refseq:NP_001288341.1|ensembl:ENSMUSG00000028312(gene)|ensembl:ENSMUST00000102915(transcript)|ensembl:ENSMUST00000117280(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051383"(kinetochore organization)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027120|interpro:IPR027417|interpro:IPR036277|mint:Q8CG48|rcsb pdb:3L51|reactome:R-MMU-2299718|reactome:R-MMU-2514853	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:A8IwiTQIuTw7BA9PQ5ZTSmxFIQA10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q99JR1	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-775916|uniprotkb:Q3UB44|uniprotkb:Q9CZG4|ensembl:ENSMUSP00000021930	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:sfxn1_mouse(display_long)|uniprotkb:Sfxn1(gene name)|psi-mi:Sfxn1(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_081600.1|refseq:XP_006516912.2|refseq:XP_006516913.1|ensembl:ENSMUSG00000021474(gene)|ensembl:ENSMUST00000021930(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0006826"(iron ion transport)|go:"GO:0015194"(L-serine transmembrane transporter activity)|go:"GO:0015825"(L-serine transport)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0022889"(serine transmembrane transporter activity)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0042942"(D-serine transport)|go:"GO:0042945"(D-serine transmembrane transporter activity)|go:"GO:0140300"(serine import into mitochondrion)|go:"GO:1990542"(mitochondrial transmembrane transport)|interpro:IPR004686(Tricarboxylate/iron carrier)|mint:Q99JR1	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:Fw53Bii/EOp13qU53qI4/06lIaE10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q8C267	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-26611589|ensembl:ENSMUSP00000093450	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:setb2_mouse(display_long)|uniprotkb:SET domain bifurcated 2(gene name synonym)|uniprotkb:Setdb2(gene name)|psi-mi:Setdb2(display_short)|uniprotkb:Gm293(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000071350(gene)|ensembl:ENSMUST00000095775(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001947"(heart looping)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0051301"(cell division)|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0070986"(left/right axis specification)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|interpro:IPR001214(SET)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR016177(DNA-binding, integrase-type)|mint:Q8C267|reactome:R-MMU-3214841	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:RPg3mWlmT3a0KiVmzMUQo+hAOSU10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:E9QAT4	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-647676|uniprotkb:A2AIX1|uniprotkb:Q80U43|uniprotkb:Q811L5|intact:EBI-8820930|intact:EBI-10045685|intact:EBI-8573308|intact:MINT-8174146|ensembl:ENSMUSP00000088796	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:sc16a_mouse(display_long)|uniprotkb:Sec16a(gene name)|psi-mi:Sec16a(display_short)|uniprotkb:Kiaa0310(gene name synonym)|uniprotkb:SEC16 homolog A(gene name synonym)|uniprotkb:Sec16(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_694765.2|refseq:XP_006497974.1|ensembl:ENSMUSG00000026924(gene)|ensembl:ENSMUST00000091252(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0031090"(organelle membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043000"(Golgi to plasma membrane CFTR protein transport)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR024298|interpro:IPR024340|interpro:IPR024880|mint:E9QAT4|reactome:R-MMU-204005|go:"GO:0032527"(protein exit from endoplasmic reticulum)	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:97WhpZFikynLgEykn8l5NJODOpo10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q91YQ5	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-642977|uniprotkb:Q3U985|ensembl:ENSMUSP00000032143	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:rpn1_mouse(display_long)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit(gene name synonym)|uniprotkb:Ribophorin-1(gene name synonym)|uniprotkb:Ribophorin I(gene name synonym)|uniprotkb:Rpn1(gene name)|psi-mi:Rpn1(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_598694.3|ensembl:ENSMUSG00000030062(gene)|ensembl:ENSMUST00000032143(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0042470"(melanosome)|interpro:IPR007676(Ribophorin I)|mint:Q91YQ5	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:fkMLaj/vo2SbXmURvjhv896RtZ410090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9D0F6	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1180268|ensembl:ENSMUSP00000083652	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:rfc5_mouse(display_long)|uniprotkb:Activator 1 subunit 5(gene name synonym)|uniprotkb:Replication factor C 36 kDa subunit(gene name synonym)|uniprotkb:Activator 1 36 kDa subunit(gene name synonym)|uniprotkb:Rfc5(gene name)|psi-mi:Rfc5(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_082404.1|ensembl:ENSMUSG00000029363(gene)|ensembl:ENSMUST00000086461(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003689"(DNA clamp loader activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|mint:Q9D0F6|reactome:R-MMU-110312|reactome:R-MMU-110314|reactome:R-MMU-110320|reactome:R-MMU-174411|reactome:R-MMU-176187|reactome:R-MMU-5651801|reactome:R-MMU-5655862|reactome:R-MMU-5656121|reactome:R-MMU-5656169|reactome:R-MMU-5685938|reactome:R-MMU-5685942|reactome:R-MMU-5693607|reactome:R-MMU-5693616|reactome:R-MMU-5696397|reactome:R-MMU-5696400|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6804756|reactome:R-MMU-69091|reactome:R-MMU-69473	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:+qImp1uvdRn0WSnuNK0y8KJ9fIs10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q8BP92	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-642694|uniprotkb:O70341|uniprotkb:A2RT07|ensembl:ENSMUSP00000109915	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:rcn2_mouse(display_long)|uniprotkb:Taipoxin-associated calcium-binding protein 49(gene name synonym)|uniprotkb:Rcn2(gene name)|psi-mi:Rcn2(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_036122.2|ensembl:ENSMUSG00000032320(gene)|ensembl:ENSMUST00000114276(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q8BP92|dip:DIP-46963N	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:vsMMmWAPrlDNQDUxzH4wrp1Jub410090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9ERU9	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-643756|uniprotkb:E9QM01|uniprotkb:Q61992|uniprotkb:Q8C9K9|ensembl:ENSMUSP00000003310	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:rbp2_mouse(display_long)|uniprotkb:Ran-binding protein 2(gene name synonym)|uniprotkb:Ranbp2(gene name)|psi-mi:Ranbp2(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_035370.2|reactome:R-MMU-191859|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3108214|reactome:R-MMU-3232142|reactome:R-MMU-3301854|reactome:R-MMU-3371453|reactome:R-MMU-4085377|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-4615885|reactome:R-MMU-5578749|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-9648025|ensembl:ENSMUSG00000003226(gene)|ensembl:ENSMUST00000003310(transcript)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006457"(protein folding)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033133"(positive regulation of glucokinase activity)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051642"(centrosome localization)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:1990723"(cytoplasmic periphery of the nuclear pore complex)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019734|interpro:IPR020892|interpro:IPR022011|interpro:IPR029000|interpro:IPR036443|mint:Q9ERU9|reactome:R-MMU-141444|reactome:R-MMU-159227|reactome:R-MMU-159230|reactome:R-MMU-159231|reactome:R-MMU-159236|reactome:R-MMU-170822	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:cjIAIF0uuxSMRXErJiJc+OBJpAw10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q3UA37	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-11570406	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:qric1_mouse(display_long)|uniprotkb:Qrich1(gene name)|psi-mi:Qrich1(display_short)|uniprotkb:Glutamine-rich protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	interpro:IPR021893|refseq:NP_001107591.1|refseq:NP_780352.2|mint:Q3UA37|go:"GO:0001822"(kidney development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0140467"(integrated stress response signaling)	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:lrPKPO53O+39Aj8JAW5xKfElPEc10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q99KP6	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-6260977|uniprotkb:Q4ADG5|ensembl:ENSMUSP00000025642|uniprotkb:Q8BKZ5|uniprotkb:Q3TP64|uniprotkb:Q8BVQ4	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:prp19_mouse(display_long)|uniprotkb:Nuclear matrix protein 200(gene name synonym)|uniprotkb:PRP19/PSO4 homolog(gene name synonym)|uniprotkb:Prp19(gene name synonym)|uniprotkb:Senescence evasion factor(gene name synonym)|uniprotkb:Snev(gene name synonym)|uniprotkb:Prpf19(gene name)|psi-mi:Prpf19(display_short)|uniprotkb:RING-type E3 ubiquitin transferase PRP19(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000024735(gene)|ensembl:ENSMUST00000025642(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005819"(spindle)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000772(Ricin B lectin)|interpro:IPR001680(WD40 repeat)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013915(Pre-mRNA-splicing factor 19)|interpro:IPR015943(WD40/YVTN repeat-like)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|interpro:IPR020472|interpro:IPR036322|interpro:IPR038959|mint:Q99KP6|reactome:R-MMU-6781823|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-72163|interpro:IPR019775|refseq:NP_001240772.1|refseq:NP_001240773.1|refseq:NP_598890.1	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:y9TwQBT+caDGqphA61AR5ysoqRg10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q8CIG8	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2527009|uniprotkb:Q3TNN1|uniprotkb:Q9QZS9	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:anm5_mouse(display_long)|uniprotkb:Prmt5(gene name)|psi-mi:Prmt5(display_short)|uniprotkb:Jbp1(gene name synonym)|uniprotkb:Skb1(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT5(gene name synonym)|uniprotkb:Shk1 kinase-binding protein 1 homolog(gene name synonym)|uniprotkb:Jak-binding protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	interpro:IPR035075|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000785"(chromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006479"(protein methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034709"(methylosome)|go:"GO:0034969"(histone arginine methylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035243"(protein-arginine omega-N symmetric methyltransferase activity)|go:"GO:0035246"(peptidyl-arginine N-methylation)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070888"(E-box binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1904992"(positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway)|reactome:R-MMU-191859|reactome:R-MMU-3214858|reactome:R-MMU-6804760|refseq:NP_038796.2|interpro:IPR007857(Skb1 methyltransferase)|interpro:IPR029063|refseq:NP_001300835.1|refseq:NP_001300836.1|interpro:IPR025799|interpro:IPR035247|interpro:IPR035248|mint:Q8CIG8	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:xMQdLXo5TNQQFK9XjxjH+5/ZwNA10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q922D4	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-4286373|uniprotkb:Q6ZPM9|uniprotkb:Q8BTW6|uniprotkb:Q9D2X9|ensembl:ENSMUSP00000025846	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:pp6r3_mouse(display_long)|uniprotkb:Ppp6r3(gene name)|psi-mi:Ppp6r3(display_short)|uniprotkb:D19Ertd703e(gene name synonym)|uniprotkb:Kiaa1558(gene name synonym)|uniprotkb:Pp6r3(gene name synonym)|uniprotkb:Saps3(gene name synonym)|uniprotkb:SAPS domain family member 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001157631.1|refseq:NP_083275.1|refseq:NP_083732.1|ensembl:ENSMUSG00000024908(gene)|ensembl:ENSMUST00000025846(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007587(SIT4 phosphatase-associated protein)|interpro:IPR016024(Armadillo-type fold)|mint:Q922D4|reactome:R-MMU-171319|reactome:R-MMU-204005|refseq:XP_006531859.1	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:cfyYAB9Ybqu8fRU64DNvVMI6zOE10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9CQR6	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-4286534|uniprotkb:A2ASL7|ensembl:ENSMUSP00000028087	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:ppp6_mouse(display_long)|uniprotkb:Ppp6c(gene name)|psi-mi:Ppp6c(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_077171.1|ensembl:ENSMUSG00000026753(gene)|ensembl:ENSMUST00000028087(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:Q9CQR6|reactome:R-MMU-171319|reactome:R-MMU-204005|go:"GO:0006470"(protein dephosphorylation)	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:R0jsZoqJLoRaSNMNCLRkQ40CC+o10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P62141	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-352338|uniprotkb:P37140|uniprotkb:Q3TBE5|uniprotkb:Q3TL90|uniprotkb:Q542E7|uniprotkb:Q8C285|uniprotkb:Q9DBY2|ensembl:ENSMUSP00000015100|ensembl:ENSMUSP00000144047	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:pp1b_mouse(display_long)|uniprotkb:Ppp1cb(gene name)|psi-mi:Ppp1cb(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_766295.2|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0016791"(phosphatase activity)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0046872"(metal ion binding)|go:"GO:0050115"(myosin-light-chain-phosphatase activity)|go:"GO:0051301"(cell division)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|mint:P62141|reactome:R-MMU-2565942|reactome:R-MMU-5625740|reactome:R-MMU-5627123|reactome:R-MMU-5673000|ensembl:ENSMUSG00000014956(gene)|ensembl:ENSMUST00000015100(transcript)|ensembl:ENSMUST00000201360(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:VtNJVyimeiEuRDDWtGswTqoSOH810090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q8BX10	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-776241|uniprotkb:Q3UK19|uniprotkb:Q80VY8|uniprotkb:Q8BM78|uniprotkb:Q9CZU2|uniprotkb:B2RSM6|ensembl:ENSMUSP00000108124	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:pgam5_mouse(display_long)|uniprotkb:Pgam5(gene name)|psi-mi:Pgam5(display_short)|uniprotkb:Phosphoglycerate mutase family member 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001157010.1|refseq:NP_082549.2|dip:DIP-32064N|ensembl:ENSMUSG00000029500(gene)|ensembl:ENSMUST00000112505(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070266"(necroptotic process)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR029033|mint:Q8BX10|reactome:R-MMU-8934903	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:m8AARXCf3lNoMo3JN7zcJNw5gwY10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q8CI51	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-299301|ensembl:ENSMUSP00000029941|uniprotkb:Q3UGD0|uniprotkb:Q9QYN0|uniprotkb:Q9QYN1|uniprotkb:Q9QYN2	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:pdli5_mouse(display_long)|uniprotkb:Pdlim5(gene name)|psi-mi:Pdlim5(display_short)|uniprotkb:Enh(gene name synonym)|uniprotkb:Enigma homolog(gene name synonym)|uniprotkb:Enigma-like PDZ and LIM domains protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000028273(gene)|ensembl:ENSMUST00000029941(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0061061"(muscle structure development)|go:"GO:0098793"(presynapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR031847|interpro:IPR036034|mint:Q8CI51|rcsb pdb:1WF7|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0007507"(heart development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0042805"(actinin binding)|go:"GO:0042995"(cell projection)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|refseq:NP_001177781.1|refseq:NP_001177783.1|refseq:NP_001177784.1|refseq:NP_001177785.1|refseq:NP_062782.2	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:w0TF6Wupq+7tBJa+NCjCSfwPA0U10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P63005	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-917499|uniprotkb:O35592|uniprotkb:P43035|uniprotkb:P81692|uniprotkb:Q9R2A6|ensembl:ENSMUSP00000021091|ensembl:ENSMUSP00000099578	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:lis1_mouse(display_long)|uniprotkb:PAF acetylhydrolase 45 kDa subunit(gene name synonym)|uniprotkb:PAF-AH alpha(gene name synonym)|uniprotkb:Lissencephaly-1 protein(gene name synonym)|uniprotkb:Pafah1b1(gene name)|psi-mi:Pafah1b1(display_short)|uniprotkb:Lis1(gene name synonym)|uniprotkb:Lis-1(gene name synonym)|uniprotkb:Pafaha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_038653.1|dip:DIP-29555N|ensembl:ENSMUSG00000020745(gene)|ensembl:ENSMUST00000021091(transcript)|ensembl:ENSMUST00000102520(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000235"(astral microtubule)|go:"GO:0000776"(kinetochore)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001675"(acrosome assembly)|go:"GO:0001764"(neuron migration)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007097"(nuclear migration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007281"(germ cell development)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007611"(learning or memory)|go:"GO:0008017"(microtubule binding)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008247"(1-alkyl-2-acetylglycerophosphocholine esterase complex)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009306"(protein secretion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016477"(cell migration)|go:"GO:0017145"(stem cell division)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0021540"(corpus callosum morphogenesis)|go:"GO:0021766"(hippocampus development)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031514"(motile cilium)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032420"(stereocilium)|go:"GO:0036035"(osteoclast development)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042249"(establishment of planar polarity of embryonic epithelium)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051130"(positive regulation of cellular component organization)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090102"(cochlea development)|go:"GO:0090176"(microtubule cytoskeleton organization involved in establishment of planar polarity)|go:"GO:0090724"(central region of growth cone)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017252(Dynein regulator)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037190|mint:P63005|rcsb pdb:1UUJ|rcsb pdb:1VYH|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9648025	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:worzim1DpTldfv3SQdodqPmMozk10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P58281	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-776163|uniprotkb:Q3ULA5|uniprotkb:Q8BKU7|uniprotkb:Q8BLL3|uniprotkb:Q8BM08|uniprotkb:Q8R3J7|uniprotkb:A6H6Q3|ensembl:ENSMUSP00000124223	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:opa1_mouse(display_long)|uniprotkb:Optic atrophy protein 1 homolog(gene name synonym)|uniprotkb:Large GTP-binding protein(gene name synonym)|uniprotkb:Opa1(gene name)|psi-mi:Opa1(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_598513.1|refseq:XP_006522720.1|ensembl:ENSMUSG00000038084(gene)|ensembl:ENSMUST00000160597(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001843"(neural tube closure)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0007601"(visual perception)|go:"GO:0008017"(microtubule binding)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0010636"(positive regulation of mitochondrial fusion)|go:"GO:0014042"(positive regulation of neuron maturation)|go:"GO:0014850"(response to muscle activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030425"(dendrite)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090102"(cochlea development)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0090398"(cellular senescence)|go:"GO:0097749"(membrane tubulation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904643"(response to curcumin)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR033047|mint:P58281|reactome:R-MMU-169911	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:cj1HZs8CYUuCBy4KhYmtO/lvmUk10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q8BJ71	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2550206|ensembl:ENSMUSP00000078878|ensembl:ENSMUSP00000105174|ensembl:ENSMUSP00000148700|uniprotkb:Q3TED9|uniprotkb:Q8BIK7|uniprotkb:Q8K1R4|uniprotkb:Q8R592	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:nup93_mouse(display_long)|uniprotkb:Nup93(gene name)|psi-mi:Nup93(display_short)|uniprotkb:Cip4(gene name synonym)|uniprotkb:Kiaa0095(gene name synonym)|uniprotkb:Nucleoporin Nup93(gene name synonym)|uniprotkb:93 kDa nucleoporin(gene name synonym)|uniprotkb:CBP-interacting protein 4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000032939(gene)|ensembl:ENSMUST00000079961(transcript)|ensembl:ENSMUST00000109547(transcript)|ensembl:ENSMUST00000212824(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005813"(centrosome)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060395"(SMAD protein signal transduction)|interpro:IPR007231(Nucleoporin interacting component)|mint:Q8BJ71|reactome:R-MMU-159227|reactome:R-MMU-159230|reactome:R-MMU-159231|reactome:R-MMU-159236|reactome:R-MMU-170822|reactome:R-MMU-191859|reactome:R-MMU-3108214|reactome:R-MMU-3232142|reactome:R-MMU-3301854|reactome:R-MMU-3371453|reactome:R-MMU-4085377|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-4615885|reactome:R-MMU-5578749|reactome:R-MMU-9615933|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|refseq:NP_765998.1|refseq:XP_006531437.1|refseq:XP_006531438.1|refseq:XP_006531439.1	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:WvpVQMDhHGIOUStAtglTjVfqUc810090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:E9Q880	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-26611574|ensembl:ENSMUSP00000130033	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:e9q880_mouse(display_long)|uniprotkb:Nup205(gene name)|psi-mi:Nup205(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000038759(gene)|ensembl:ENSMUST00000170234(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0051292"(nuclear pore complex assembly)|mint:E9Q880|interpro:IPR021827	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:0CB6w4pCAOv5PDnEK9GqDjg1SGg10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9Z0W3	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-6876823|ensembl:ENSMUSP00000059289|uniprotkb:Q3TBI7|uniprotkb:Q3TP11|uniprotkb:Q3U250|uniprotkb:Q6A0A7|uniprotkb:Q7TME1|uniprotkb:Q9CZD9	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:nu160_mouse(display_long)|uniprotkb:Nup160(gene name)|psi-mi:Nup160(display_short)|uniprotkb:Gtl1-13(gene name synonym)|uniprotkb:Kiaa0197(gene name synonym)|uniprotkb:160 kDa nucleoporin(gene name synonym)|uniprotkb:Gene trap locus 1-13 protein(gene name synonym)|uniprotkb:Nucleoporin Nup160(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000051329(gene)|ensembl:ENSMUST00000057481(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005643"(nuclear pore)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0015031"(protein transport)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0072006"(nephron development)|interpro:IPR021717|mint:Q9Z0W3|reactome:R-MMU-141444|reactome:R-MMU-159227|reactome:R-MMU-159230|reactome:R-MMU-159231|reactome:R-MMU-159236|reactome:R-MMU-191859|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3108214|reactome:R-MMU-3232142|reactome:R-MMU-3301854|reactome:R-MMU-3371453|reactome:R-MMU-4085377|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-4615885|reactome:R-MMU-5578749|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-9615933|reactome:R-MMU-9648025|reactome:R-MMU-170822|refseq:XP_006500031.1|refseq:NP_067487.1	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:gBPhZJ6kAbFHcjQAHCbwqkBJCFg10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q99P88	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2551981|ensembl:ENSMUSP00000128819	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:nu155_mouse(display_long)|uniprotkb:Nucleoporin Nup155(gene name synonym)|uniprotkb:155 kDa nucleoporin(gene name synonym)|uniprotkb:Nup155(gene name)|psi-mi:Nup155(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	mint:Q99P88|reactome:R-MMU-159227|reactome:R-MMU-159230|reactome:R-MMU-159231|reactome:R-MMU-159236|reactome:R-MMU-170822|reactome:R-MMU-191859|reactome:R-MMU-3108214|reactome:R-MMU-3232142|reactome:R-MMU-3301854|reactome:R-MMU-3371453|reactome:R-MMU-4085377|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-4615885|reactome:R-MMU-5578749|reactome:R-MMU-9615933|interpro:IPR042538|ensembl:ENSMUSG00000022142(gene)|ensembl:ENSMUST00000163765(transcript)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|interpro:IPR004870(Nucleoporin, non-repetitive/WGA-negative)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR014908(Nup133, N-terminal)|interpro:IPR042533|interpro:IPR042537|refseq:NP_573490.3	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:VNP6KXs2IzDvHc7Q0re9FpjB/lo10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q6DFW4	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-6260951|ensembl:ENSMUSP00000140250|uniprotkb:Q8C8Y7|uniprotkb:Q3UZA3|uniprotkb:O70396|uniprotkb:Q3UYX9	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:nop58_mouse(display_long)|uniprotkb:MSSP(gene name synonym)|uniprotkb:Nol5(gene name synonym)|uniprotkb:Nucleolar protein 5(gene name synonym)|uniprotkb:SIK-similar protein(gene name synonym)|uniprotkb:Nop58(gene name)|psi-mi:Nop58(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000026020(gene)|ensembl:ENSMUST00000191142(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0048254"(snoRNA localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0070761"(pre-snoRNP complex)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|mint:Q6DFW4|reactome:R-MMU-4570464|reactome:R-MMU-6791226|refseq:NP_061356.2	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:gx/F5iCI7SIdIqpZobsk4CcPd/I10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9ERR1	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-646668|uniprotkb:Q9D0Q4|uniprotkb:Q9EPT6|ensembl:ENSMUSP00000018880	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:ndel1_mouse(display_long)|uniprotkb:Protein mNudE-like(gene name synonym)|uniprotkb:Ndel1(gene name)|psi-mi:Ndel1(display_short)|uniprotkb:Nudel(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_076157.2|dip:DIP-29553N|ensembl:ENSMUSG00000018736(gene)|ensembl:ENSMUST00000018880(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000776"(kinetochore)|go:"GO:0001764"(neuron migration)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0016477"(cell migration)|go:"GO:0021799"(cerebral cortex radially oriented cell migration)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030424"(axon)|go:"GO:0031175"(neuron projection development)|go:"GO:0031252"(cell leading edge)|go:"GO:0032418"(lysosome localization)|go:"GO:0033157"(regulation of intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043203"(axon hillock)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051642"(centrosome localization)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0060053"(neurofilament cytoskeleton)|go:"GO:0070012"(oligopeptidase activity)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0090724"(central region of growth cone)|go:"GO:1900029"(positive regulation of ruffle assembly)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990138"(neuron projection extension)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR033493|interpro:IPR033494|mint:Q9ERR1|rcsb pdb:5YI4|rcsb pdb:6KZJ|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-9648025|interpro:IPR006964(NUDE protein, C-terminal)	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:c69FdVwX1uLP9KZrbrhxKlgGO3c10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9CZA6	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-309934|uniprotkb:Q3UBS6|uniprotkb:Q3UIC1|uniprotkb:Q9ERR0|ensembl:ENSMUSP00000023359	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:nde1_mouse(display_long)|uniprotkb:Nde1(gene name)|psi-mi:Nde1(display_short)|uniprotkb:Nude(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001107557.1|refseq:NP_075806.2|refseq:NP_001272432.1|refseq:NP_001272433.1|refseq:XP_011244302.1|ensembl:ENSMUSG00000022678(gene)|ensembl:ENSMUST00000023359(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030900"(forebrain development)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051642"(centrosome localization)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|mint:Q9CZA6|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9648025|dip:DIP-54638N	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:711HNgfdXkDQEAEhRwa4DjKah5s10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9Z0E0	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-775082|uniprotkb:Q3TCW4|uniprotkb:Q80TW1|uniprotkb:Q91YH7|uniprotkb:Q9CW81|uniprotkb:Q9QUQ0|ensembl:ENSMUSP00000030637|ensembl:ENSMUSP00000101722	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:ncdn_mouse(display_long)|uniprotkb:Sfap75(gene name synonym)|uniprotkb:Norbin(gene name synonym)|uniprotkb:M-Sema F-associating protein of 75 kDa(gene name synonym)|uniprotkb:Ncdn(gene name)|psi-mi:Ncdn(display_short)|uniprotkb:Kiaa0607(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_036116.3|refseq:XP_006503181.1|refseq:XP_006503182.1|ensembl:ENSMUSG00000028833(gene)|ensembl:ENSMUST00000030637(transcript)|ensembl:ENSMUST00000106116(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0045453"(bone resorption)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0098794"(postsynapse)|interpro:IPR008709(Neurochondrin)|interpro:IPR016024(Armadillo-type fold)|mint:Q9Z0E0	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:afzLC/h+kiexMllkeyxpn1btb1U10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q6ZQK0	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-12739065|uniprotkb:E9QPR0|uniprotkb:Q9CS21	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:cndd3_mouse(display_long)|uniprotkb:Ncapd3(gene name)|psi-mi:Ncapd3(display_short)|uniprotkb:Kiaa0056(gene name synonym)|uniprotkb:Non-SMC condensin II complex subunit D3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042585"(germinal vesicle)|go:"GO:0051301"(cell division)|go:"GO:0051307"(meiotic chromosome separation)|reactome:R-MMU-2299718|interpro:IPR026971|refseq:NP_835214.2|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR032682|interpro:IPR012371(Chromosome condensation protein, HCP-6-related)|mint:Q6ZQK0	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:ceNFQFDdld5L64HaA9vpqJo/MU810090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q8CH77	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-16732405|uniprotkb:Q3U5B6|uniprotkb:Q68EE8|uniprotkb:Q6PB78|uniprotkb:Q80TI7|uniprotkb:Q8BKG2|uniprotkb:Q8BUT5|ensembl:ENSMUSP00000043803|ensembl:ENSMUSP00000067241	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:nav1_mouse(display_long)|uniprotkb:Pore membrane and/or filament-interacting-like protein 3(gene name synonym)|uniprotkb:Nav1(gene name)|psi-mi:Nav1(display_short)|uniprotkb:Kiaa1151(gene name synonym)|uniprotkb:Pomfil3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_775613.2|ensembl:ENSMUSG00000009418(gene)|ensembl:ENSMUST00000040599(transcript)|ensembl:ENSMUST00000067414(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007399"(nervous system development)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0043194"(axon initial segment)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|interpro:IPR039041|mint:Q8CH77|go:"GO:0001578"(microtubule bundle formation)	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:6JEY5QgG5i9X72Lw1SklaXm186U10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:A6H5Y3	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-26611533|ensembl:ENSMUSP00000097442|uniprotkb:Q3UQP2	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:meth_mouse(display_long)|uniprotkb:5-methyltetrahydrofolate--homocysteine methyltransferase(gene name synonym)|uniprotkb:Cobalamin-dependent methionine synthase(gene name synonym)|uniprotkb:Vitamin-B12 dependent methionine synthase(gene name synonym)|uniprotkb:Mtr(gene name)|psi-mi:Mtr(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000021311(gene)|ensembl:ENSMUST00000099856(transcript)|go:"GO:0005542"(folic acid binding)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0006555"(methionine metabolic process)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008705"(methionine synthase activity)|go:"GO:0009086"(methionine biosynthetic process)|go:"GO:0009235"(cobalamin metabolic process)|go:"GO:0016597"(amino acid binding)|go:"GO:0031103"(axon regeneration)|go:"GO:0031419"(cobalamin binding)|go:"GO:0046653"(tetrahydrofolate metabolic process)|go:"GO:0048678"(response to axon injury)|go:"GO:0050667"(homocysteine metabolic process)|go:"GO:0071732"(cellular response to nitric oxide)|interpro:IPR003726(Homocysteine S-methyltransferase)|interpro:IPR003759("Methionine synthase, cobalamin (vitamin B12)-binding module, cap")|interpro:IPR004223(Vitamin B12 dependent methionine synthase, activation region)|interpro:IPR006158("Cobalamin (vitamin B12)-binding")|interpro:IPR011005(Dihydropteroate synthase-like)|interpro:IPR011822(5-methyltetrahydrofolate--homocysteine methyltransferase)|interpro:IPR033706|interpro:IPR036589|interpro:IPR036594|interpro:IPR036724|interpro:IPR037010|mint:A6H5Y3|reactome:R-MMU-156581|reactome:R-MMU-1614635|reactome:R-MMU-196741|reactome:R-MMU-9013407|interpro:IPR000489(Dihydropteroate synthase, DHPS)|refseq:NP_001074597.1	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:m5N9w85R9HKDMe+DL+CRxZ5h7wg10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q99MB2	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-26611507|ensembl:ENSMUSP00000112752|ensembl:ENSMUSP00000112824|ensembl:ENSMUSP00000119724|uniprotkb:Q9CQZ4	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:mtfr1_mouse(display_long)|uniprotkb:Chondrocyte protein with a poly-proline region(gene name synonym)|uniprotkb:Mtfr1(gene name)|psi-mi:Mtfr1(display_short)|uniprotkb:Chppr(gene name synonym)|uniprotkb:Kiaa0009(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000027601(gene)|ensembl:ENSMUST00000117529(transcript)|ensembl:ENSMUST00000119865(transcript)|ensembl:ENSMUST00000130645(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0009060"(aerobic respiration)|interpro:IPR007972(Protein of unknown function DUF729)|mint:Q99MB2|refseq:NP_001240319.1|refseq:NP_001240320.1|refseq:NP_080458.1|refseq:XP_006535589.1|refseq:XP_011248010.1	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:mMpfdyryXTBLLFXLYCnoV1QrLCw10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q99KX1	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-646781|ensembl:ENSMUSP00000032214|ensembl:ENSMUSP00000135920	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:mlf2_mouse(display_long)|uniprotkb:Myelodysplasia-myeloid leukemia factor 2(gene name synonym)|uniprotkb:Mlf2(gene name)|psi-mi:Mlf2(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001163812.1|refseq:NP_663360.1|ensembl:ENSMUSG00000030120(gene)|ensembl:ENSMUST00000032214(transcript)|ensembl:ENSMUST00000180095(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR019376|mint:Q99KX1	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:/TTRBTfO7JkzWbvIALSR+GeA5aU10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q5U481	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-26611494	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:q5u481_mouse(display_long)|uniprotkb:Mdn1(gene name)|psi-mi:Mdn1(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0045111"(intermediate filament cytoskeleton)|mint:Q5U481|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR036465	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:g0jGUWHcfNZgAjKbl8JaUNrB+aY10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q61881	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-457180|ensembl:ENSMUSP00000000505	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:mcm7_mouse(display_long)|uniprotkb:CDC47 homolog(gene name synonym)|uniprotkb:Mcm7(gene name)|psi-mi:Mcm7(display_short)|uniprotkb:Cdc47(gene name synonym)|uniprotkb:Mcmd7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_032594.1|ensembl:ENSMUSG00000029730(gene)|ensembl:ENSMUST00000000505(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008283"(cell population proliferation)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:Q61881|reactome:R-MMU-176187|reactome:R-MMU-68867|reactome:R-MMU-68949|reactome:R-MMU-68962|reactome:R-MMU-69052|dip:DIP-45877N	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:qq7mNMv+SBxpq5F/NH+86/IXmPI10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q8K310	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1216295|ensembl:ENSMUSP00000125761|ensembl:ENSMUSP00000158074|ensembl:ENSMUSP00000158537	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:matr3_mouse(display_long)|uniprotkb:Matr3(gene name)|psi-mi:Matr3(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_034901.2|rcsb pdb:1X4F|rcsb pdb:1X4D|ensembl:ENSMUSG00000037236(gene)|ensembl:ENSMUST00000166793(transcript)|ensembl:ENSMUST00000235199(transcript)|ensembl:ENSMUST00000237744(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003170"(heart valve development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034928|interpro:IPR034930|interpro:IPR035979|mint:Q8K310	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:AwtFbI+oRfha+mn/v3yzG6bNXYg10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P63085	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-397697|uniprotkb:P27703|uniprotkb:Q3V1U6|ensembl:ENSMUSP00000156154|ensembl:ENSMUSP00000065983|ensembl:ENSMUSP00000111396	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:mk01_mouse(display_long)|uniprotkb:Mapk1(gene name)|psi-mi:Mapk1(display_short)|uniprotkb:Erk2(gene name synonym)|uniprotkb:Mapk(gene name synonym)|uniprotkb:Prkm1(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 2(gene name synonym)|uniprotkb:MAP kinase isoform p42(gene name synonym)|uniprotkb:ERT1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001033752.1|refseq:NP_036079.1|refseq:XP_006522210.1|dip:DIP-661N|ensembl:ENSMUST00000069107(transcript)|ensembl:ENSMUST00000115731(transcript)|ensembl:ENSMUST00000232611(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015966"(diadenosine tetraphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019858"(cytosine metabolic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030424"(axon)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035094"(response to nicotine)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043627"(response to estrogen)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046697"(decidualization)|go:"GO:0048538"(thymus development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P63085|reactome:R-MMU-111995|reactome:R-MMU-112409|reactome:R-MMU-112411|reactome:R-MMU-1295596|reactome:R-MMU-162658|reactome:R-MMU-170968|reactome:R-MMU-198753|reactome:R-MMU-202670|reactome:R-MMU-2029482|reactome:R-MMU-2559580|reactome:R-MMU-2559582|reactome:R-MMU-2559585|reactome:R-MMU-2871796|reactome:R-MMU-3371453|reactome:R-MMU-375165|reactome:R-MMU-437239|reactome:R-MMU-445144|reactome:R-MMU-450341|reactome:R-MMU-456926|reactome:R-MMU-5654726|reactome:R-MMU-5654727|reactome:R-MMU-5654732|reactome:R-MMU-5654733|reactome:R-MMU-5663213|reactome:R-MMU-5668599|reactome:R-MMU-5673001|reactome:R-MMU-5674135|reactome:R-MMU-5674499|reactome:R-MMU-5675221|reactome:R-MMU-6798695|reactome:R-MMU-6811558|reactome:R-MMU-74749|reactome:R-MMU-881907|reactome:R-MMU-8939211|reactome:R-MMU-9627069|reactome:R-MMU-9634635|ensembl:ENSMUSG00000063358(gene)|reactome:R-MMU-9634638|reactome:R-MMU-982772	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:4STZhl2O+Ilh0lj8wQp8y2vVehA10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P14873	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-764653|uniprotkb:E9QM11|ensembl:ENSMUSP00000068374	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:map1b_mouse(display_long)|uniprotkb:MAP1.2(gene name synonym)|uniprotkb:"MAP1(X)"(gene name synonym)|uniprotkb:Map1b(gene name)|psi-mi:Map1b(display_short)|uniprotkb:Mtap1b(gene name synonym)|uniprotkb:Mtap5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_032660.2|ensembl:ENSMUSG00000052727(gene)|ensembl:ENSMUST00000064762(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003779"(actin binding)|go:"GO:0005519"(cytoskeletal regulatory protein binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007416"(synapse assembly)|go:"GO:0008017"(microtubule binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009987"(cellular process)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017085"(response to insecticide)|go:"GO:0021700"(developmental maturation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031114"(regulation of microtubule depolymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0033189"(response to vitamin A)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|go:"GO:0043196"(varicosity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0016358"(dendrite development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0051915"(induction of synaptic plasticity by chemical substance)|go:"GO:0061162"(establishment of monopolar cell polarity)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0097440"(apical dendrite)|go:"GO:0097441"(basal dendrite)|go:"GO:0097457"(hippocampal mossy fiber)|interpro:IPR000102(Neuraxin/MAP1B repeat)|interpro:IPR026074|interpro:IPR027321|mint:P14873	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:8Ph5u01KvXbfedKGBXu5cGckp7Y10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9QYR6	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-774021|uniprotkb:A2ARN9|uniprotkb:Q3TQM8|uniprotkb:Q3TUV8|uniprotkb:Q3UHB7|uniprotkb:Q9QZH9|uniprotkb:Q9QZI0|uniprotkb:Q9QZI1|ensembl:ENSMUSP00000106269	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:map1a_mouse(display_long)|uniprotkb:Map1a(gene name)|psi-mi:Map1a(display_short)|uniprotkb:Mtap1(gene name synonym)|uniprotkb:Mtap1a(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001166977.1|refseq:NP_115769.1|ensembl:ENSMUSG00000027254(gene)|ensembl:ENSMUST00000110639(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003779"(actin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007613"(memory)|go:"GO:0008017"(microtubule binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008306"(associative learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016358"(dendrite development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031114"(regulation of microtubule depolymerization)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043194"(axon initial segment)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044307"(dendritic branch)|go:"GO:0045202"(synapse)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:0099642"(retrograde axonal protein transport)|go:"GO:0150001"(primary dendrite)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1902817"(negative regulation of protein localization to microtubule)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990535"(neuron projection maintenance)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR015656(MAP1A)|interpro:IPR026074|interpro:IPR036866|mint:Q9QYR6|rcsb pdb:5GNV	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:YFVfrv4h8ioQ9vL1A9LYsA5xriQ10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q3TFU3	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-26611480	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:q3tfu3_mouse(display_long)|uniprotkb:Maged2(gene name)|psi-mi:Maged2(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007565"(female pregnancy)|go:"GO:0070294"(renal sodium ion absorption)|mint:Q3TFU3|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|interpro:IPR028810|interpro:IPR002190(MAGE protein)	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:5P1wP7+fTdmTm+EkAP2GIMttox010090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9QYH6	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1801274|uniprotkb:Q543L6|uniprotkb:Q99PB5|uniprotkb:Q9CYX1|ensembl:ENSMUSP00000026142	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:magd1_mouse(display_long)|uniprotkb:Maged1(gene name)|psi-mi:Maged1(display_short)|uniprotkb:Nrage(gene name synonym)|uniprotkb:MAGE-D1 antigen(gene name synonym)|uniprotkb:Neurotrophin receptor-interacting MAGE homolog(gene name synonym)|uniprotkb:Dlxin-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_062765.1|interpro:IPR041898|interpro:IPR041899|mint:Q9QYH6|ensembl:ENSMUSG00000025151(gene)|ensembl:ENSMUST00000026142(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR030083|interpro:IPR037445	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:yQjDWQnoyOmw1R+BGkK3EO5blik10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9Z1B5	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2552918|ensembl:ENSMUSP00000098897|ensembl:ENSMUSP00000112304|uniprotkb:Q9JI53	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:md2l1_mouse(display_long)|uniprotkb:Mad2l1(gene name)|psi-mi:Mad2l1(display_short)|uniprotkb:Mad2a(gene name synonym)|uniprotkb:Mitotic arrest deficient 2-like protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_062372.2|reactome:R-MMU-2500257|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-9648025|reactome:R-MMU-2467813|ensembl:ENSMUSG00000029910(gene)|ensembl:ENSMUST00000101343(transcript)|ensembl:ENSMUST00000116605(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR036570|mint:Q9Z1B5|reactome:R-MMU-141405|reactome:R-MMU-141430|reactome:R-MMU-141444|reactome:R-MMU-174184|reactome:R-MMU-176409|reactome:R-MMU-179409|refseq:XP_006506469.1	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:T2SuApPGRno6LWCTPwVqAvQEVZQ10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9QXD8	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1565949|uniprotkb:Q8C8G4|uniprotkb:Q9CW55|ensembl:ENSMUSP00000026269	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:limd1_mouse(display_long)|uniprotkb:Limd1(gene name)|psi-mi:Limd1(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_038888.2|dip:DIP-38453N|ensembl:ENSMUSG00000025239(gene)|ensembl:ENSMUST00000026269(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002076"(osteoblast development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016310"(phosphorylation)|go:"GO:0016442"(RISC complex)|go:"GO:0016477"(cell migration)|go:"GO:0033962"(P-body assembly)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR028734|mint:Q9QXD8|reactome:R-MMU-1234176	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:l5HpR5SwbKwqzy6a/WUkwnKVkck10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:A2BE28	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-6909575|ensembl:ENSMUSP00000109495|uniprotkb:A2BE30|uniprotkb:Q6KAR5|uniprotkb:Q8C742	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:las1l_mouse(display_long)|uniprotkb:Las1l(gene name)|psi-mi:Las1l(display_short)|uniprotkb:Protein LAS1 homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:XP_006528397.1|ensembl:ENSMUSG00000057421(gene)|ensembl:ENSMUST00000113864(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005730"(nucleolus)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090730"(Las1 complex)|interpro:IPR007174(Las1-like)|mint:A2BE28|reactome:R-MMU-6791226|refseq:NP_690035.2	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:Mhldr72nVCrOq1rjpRDqIcqNsg810090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P70168	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-540580|uniprotkb:Q62117|uniprotkb:Q6GTI5|ensembl:ENSMUSP00000001479	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:imb1_mouse(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym)|uniprotkb:SCG(gene name synonym)|uniprotkb:Kpnb1(gene name)|psi-mi:Kpnb1(display_short)|uniprotkb:Impnb(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_032405.3|ensembl:ENSMUSG00000001440(gene)|ensembl:ENSMUST00000001479(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0010494"(cytoplasmic stress granule)|reactome:R-MMU-2995383|reactome:R-MMU-6798695|reactome:R-MMU-909733|reactome:R-MMU-1655829|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:P70168|rcsb pdb:1GCJ|rcsb pdb:1UKL|go:"GO:0019894"(kinesin binding)|reactome:R-MMU-140342|dip:DIP-33404N	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:rYDCcZYUZp8TbcpyJE7pfz5+bvo10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P52293	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-3043908|ensembl:ENSMUSP00000018506|ensembl:ENSMUSP00000137310|uniprotkb:Q64292	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:ima1_mouse(display_long)|uniprotkb:Kpna2(gene name)|psi-mi:Kpna2(display_short)|uniprotkb:Rch1(gene name synonym)|uniprotkb:Importin alpha P1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-2(gene name synonym)|uniprotkb:Pendulin(gene name synonym)|uniprotkb:Pore targeting complex 58 kDa subunit(gene name synonym)|uniprotkb:RAG cohort protein 1(gene name synonym)|uniprotkb:SRP1-alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000018362(gene)|ensembl:ENSMUSG00000066878(gene)|ensembl:ENSMUST00000018506(transcript)|ensembl:ENSMUST00000086423(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043657"(host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:0098892"(extrinsic component of postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:P52293|rcsb pdb:1EJL|rcsb pdb:1EJY|rcsb pdb:1IAL|rcsb pdb:1IQ1|rcsb pdb:1PJM|rcsb pdb:1PJN|rcsb pdb:1Q1S|rcsb pdb:1Q1T|rcsb pdb:1Y2A|rcsb pdb:2C1M|rcsb pdb:2YNR|rcsb pdb:3BTR|rcsb pdb:3KND|rcsb pdb:3L3Q|rcsb pdb:3OQS|rcsb pdb:3Q5U|rcsb pdb:3RZ9|rcsb pdb:3RZX|rcsb pdb:3TPM|rcsb pdb:3TPO|rcsb pdb:3UKW|rcsb pdb:3UKX|rcsb pdb:3UKZ|rcsb pdb:3UL0|rcsb pdb:3UL1|rcsb pdb:3UVU|rcsb pdb:3VE6|rcsb pdb:3ZIN|rcsb pdb:3ZIO|rcsb pdb:3ZIP|rcsb pdb:3ZIQ|rcsb pdb:3ZIR|rcsb pdb:4BA3|rcsb pdb:4HTV|rcsb pdb:4MZ5|rcsb pdb:4MZ6|rcsb pdb:4OIH|rcsb pdb:4U54|rcsb pdb:4U58|rcsb pdb:4U5L|rcsb pdb:4U5N|rcsb pdb:4U5O|rcsb pdb:4U5S|rcsb pdb:4U5U|rcsb pdb:4U5V|rcsb pdb:4UAF|rcsb pdb:4YI0|rcsb pdb:4ZDU|rcsb pdb:5B56|rcsb pdb:5CTT|rcsb pdb:5D5K|rcsb pdb:5E6Q|rcsb pdb:5EKF|rcsb pdb:5EKG|rcsb pdb:5FC8|rcsb pdb:5GXW|rcsb pdb:3UKY|rcsb pdb:5HHG|rcsb pdb:5HUW|rcsb pdb:5HUY|rcsb pdb:5K9S|rcsb pdb:5KLR|rcsb pdb:5SVZ|rcsb pdb:5U5P|rcsb pdb:5U5R|rcsb pdb:5UMZ|rcsb pdb:5V5O|rcsb pdb:5V5P|rcsb pdb:5W41|rcsb pdb:5W4E|rcsb pdb:5W4F|rcsb pdb:5W4G|rcsb pdb:5WUM|rcsb pdb:5WUN|rcsb pdb:5X8N|rcsb pdb:6BVT|rcsb pdb:6BW0|rcsb pdb:6BW1|rcsb pdb:6D7M|rcsb pdb:6D7N|rcsb pdb:6IU7|rcsb pdb:6IUA|rcsb pdb:5KLT|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|rcsb pdb:6MJL|rcsb pdb:6P6A|rcsb pdb:6P6E|rcsb pdb:6WX7|rcsb pdb:7JJM|rcsb pdb:7JK7|rcsb pdb:7JVO|rcsb pdb:7L04|reactome:R-MMU-5693548|refseq:NP_034785.1|dip:DIP-47774N	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:qML5OVHqAJODiP+FSG9fTsiV3JQ10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9JK45	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-26611455|ensembl:ENSMUSP00000029667|uniprotkb:Q4QXS5|uniprotkb:Q8BSF6	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:kcnq5_mouse(display_long)|uniprotkb:KQT-like 5(gene name synonym)|uniprotkb:Potassium channel subunit alpha KvLQT5(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.5(gene name synonym)|uniprotkb:Kcnq5(gene name)|psi-mi:Kcnq5(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000028033(gene)|ensembl:ENSMUST00000029667(transcript)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030118"(clathrin coat)|go:"GO:0071805"(potassium ion transmembrane transport)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR028325|interpro:IPR043238|mint:Q9JK45|reactome:R-MMU-1296072|go:"GO:0034765"(regulation of ion transmembrane transport)|refseq:NP_076361.1	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:9rcmsEZqUifPoZ45O3VbX2h/sWo10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9Z0Y7	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-26611432|ensembl:ENSMUSP00000067085|uniprotkb:A2BHF6|uniprotkb:Q8BRB9	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:irs4_mouse(display_long)|uniprotkb:Phosphoprotein of 160 kDa(gene name synonym)|uniprotkb:Irs4(gene name)|psi-mi:Irs4(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000054667(gene)|ensembl:ENSMUST00000067841(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|mint:Q9Z0Y7|reactome:R-MMU-2428928|refseq:NP_034702.2	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:1BIZtudg2MVW9l352S45JsvIkoE10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q62406	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-448533|uniprotkb:Q6Y3Z5|uniprotkb:Q6Y3Z6|uniprotkb:B1AUW4|ensembl:ENSMUSP00000064448|ensembl:ENSMUSP00000109992	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:irak1_mouse(display_long)|uniprotkb:Pelle-like protein kinase(gene name synonym)|uniprotkb:Irak1(gene name)|psi-mi:Irak1(display_short)|uniprotkb:Il1rak(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001171447.1|refseq:NP_032389.2|refseq:NP_001171445.1|dip:DIP-31491N|ensembl:ENSMUSG00000031392(gene)|ensembl:ENSMUST00000068286(transcript)|ensembl:ENSMUST00000114352(transcript)|go:"GO:0001959"(regulation of cytokine-mediated signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007254"(JNK cascade)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034134"(toll-like receptor 2 signaling pathway)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090370"(negative regulation of cholesterol efflux)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035533|interpro:IPR035536|mint:Q62406|reactome:R-MMU-1257604|reactome:R-MMU-168638|reactome:R-MMU-209543|reactome:R-MMU-209560|reactome:R-MMU-445989|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|reactome:R-MMU-450321|reactome:R-MMU-6811558|reactome:R-MMU-9020702|reactome:R-MMU-937039|reactome:R-MMU-975144|reactome:R-MMU-450302	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:f0/zWzQ/pwn4saHTcFh7pChaKIQ10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9EPL8	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2550269|ensembl:ENSMUSP00000081782|uniprotkb:Q7TN09|uniprotkb:Q7TQ63|uniprotkb:Q8BKD8|uniprotkb:Q8BYI0	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:ipo7_mouse(display_long)|uniprotkb:Ipo7(gene name)|psi-mi:Ipo7(display_short)|uniprotkb:Ranbp7(gene name synonym)|uniprotkb:Ran-binding protein 7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000066232(gene)|ensembl:ENSMUST00000084731(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042393"(histone binding)|go:"GO:0045087"(innate immune response)|go:"GO:0046332"(SMAD binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:Q9EPL8|refseq:NP_852658.2	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:YOGtbOzeE6Oq5T0J42GWW7fH9H010090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q8CAQ8	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-776087|uniprotkb:Q66JS4|uniprotkb:Q7TNE2|uniprotkb:Q8C7V1|uniprotkb:Q8CCI0|uniprotkb:Q8CDA8|uniprotkb:Q9D9F6|ensembl:ENSMUSP00000066181	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:mic60_mouse(display_long)|uniprotkb:Mitofilin(gene name synonym)|uniprotkb:Immt(gene name)|psi-mi:Immt(display_short)|uniprotkb:Mic60(gene name synonym)|uniprotkb:Mitochondrial inner membrane protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_083949.2|refseq:NP_001240617.1|refseq:NP_001240610.1|refseq:NP_001240616.1|dip:DIP-32050N|ensembl:ENSMUSG00000052337(gene)|ensembl:ENSMUST00000064062(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|mint:Q8CAQ8|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0042407"(cristae formation)|go:"GO:0043209"(myelin sheath)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0061617"(MICOS complex)|interpro:IPR019133	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:fW23bvuLqjLn5wIOu6ycDsh7O1k10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:A0A1Y7VNI1	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-26611410|ensembl:ENSMUSP00000152435	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:a0a1y7vni1_mouse(display_long)|uniprotkb:Heatr1(gene name)|psi-mi:Heatr1(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000050244(gene)|ensembl:ENSMUST00000222091(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030515"(snoRNA binding)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034455"(t-UTP complex)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012954(BP28, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040191|mint:A0A1Y7VNI1	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:GzaiDsvlw26mhTWQT11lkK6vMd410090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P70217	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-925264|uniprotkb:Q2VPB0|uniprotkb:A2ASM5|uniprotkb:Q2VPB1|uniprotkb:Q64177|ensembl:ENSMUSP00000001872	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:hxd13_mouse(display_long)|uniprotkb:Hoxd13(gene name)|psi-mi:Hoxd13(display_short)|uniprotkb:Hox-4.8(gene name synonym)|uniprotkb:Homeobox protein Hox-4.8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_032301.2|ensembl:ENSMUSG00000001819(gene)|ensembl:ENSMUST00000001872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030539"(male genitalia development)|go:"GO:0033574"(response to testosterone)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060571"(morphogenesis of an epithelial fold)|go:"GO:0060602"(branch elongation of an epithelium)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR022067|mint:P70217	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:FWeR98eKeTKa8R6EG03n7Gelgi410090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:O09106	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-301912|uniprotkb:P97476|ensembl:ENSMUSP00000099657	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:hdac1_mouse(display_long)|uniprotkb:Hdac1(gene name)|psi-mi:Hdac1(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	dip:DIP-31499N|ensembl:ENSMUSG00000028800(gene)|ensembl:ENSMUST00000102597(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|refseq:NP_032254.1|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:O09106|reactome:R-MMU-1538133|reactome:R-MMU-201722|reactome:R-MMU-2173795|reactome:R-MMU-3214815|reactome:R-MMU-350054|reactome:R-MMU-3769402|reactome:R-MMU-4551638|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8936459|reactome:R-MMU-8943724|reactome:R-MMU-9018519|reactome:R-MMU-9022692|reactome:R-MMU-983231|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031000"(response to caffeine)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007492"(endoderm development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0001046"(core promoter sequence-specific DNA binding)	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:P7QV++FiMiNcabUkswbnNhGVU3410090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:O35387	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-642449|uniprotkb:Q542F8|ensembl:ENSMUSP00000078661	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:hax1_mouse(display_long)|uniprotkb:HS1-associating protein X-1(gene name synonym)|uniprotkb:HS1-binding protein 1(gene name synonym)|uniprotkb:Hax1(gene name)|psi-mi:Hax1(display_short)|uniprotkb:Hs1bp1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_035956.1|ensembl:ENSMUSG00000027944(gene)|ensembl:ENSMUST00000079724(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005938"(cell cortex)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019966"(interleukin-1 binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR017248(HS1-associating, X-1)|mint:O35387|dip:DIP-49445N	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:Jsw3mjyZheyvkAXjJXFOWduNC4s10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q8R2T8	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-11516726|uniprotkb:Q8BLE3|uniprotkb:Q8R0D0|ensembl:ENSMUSP00000109521	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:tf3c5_mouse(display_long)|uniprotkb:TF3C-epsilon(gene name synonym)|uniprotkb:Transcription factor IIIC 63 kDa subunit(gene name synonym)|uniprotkb:Transcription factor IIIC subunit epsilon(gene name synonym)|uniprotkb:Gtf3c5(gene name)|psi-mi:Gtf3c5(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001277413.1|refseq:NP_683730.1|ensembl:ENSMUSG00000026816(gene)|ensembl:ENSMUST00000113889(transcript)|go:"GO:0000127"(transcription factor TFIIIC complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006384"(transcription initiation from RNA polymerase III promoter)|go:"GO:0035914"(skeletal muscle cell differentiation)|interpro:IPR019136|interpro:IPR040454|interpro:IPR041499|interpro:IPR042536|mint:Q8R2T8|reactome:R-MMU-76061|reactome:R-MMU-76066	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:d9jKi16JoEdZRlL74RmmQCfmT4I10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q60631	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1688|uniprotkb:Q61240|ensembl:ENSMUSP00000021090|ensembl:ENSMUSP00000102106	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:grb2_mouse(display_long)|uniprotkb:Grb2(gene name)|psi-mi:Grb2(display_short)|uniprotkb:Adapter protein GRB2(gene name synonym)|uniprotkb:SH2/SH3 adapter GRB2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_032189.1|refseq:NP_001300865.1|refseq:NP_001300866.1|dip:DIP-259N|ensembl:ENSMUSG00000059923(gene)|ensembl:ENSMUST00000021090(transcript)|ensembl:ENSMUST00000106497(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005168"(neurotrophin TRKA receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007568"(aging)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031623"(receptor internalization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|go:"GO:0070436"(Grb2-EGFR complex)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035641|interpro:IPR035643|interpro:IPR036028|interpro:IPR036860|mint:Q60631|rcsb pdb:1GBQ|rcsb pdb:1GBR|rcsb pdb:2GBQ|rcsb pdb:3GBQ|rcsb pdb:4GBQ|reactome:R-MMU-109704|reactome:R-MMU-112412|reactome:R-MMU-1250347|reactome:R-MMU-1257604|reactome:R-MMU-1295596|reactome:R-MMU-1433557|reactome:R-MMU-1433559|reactome:R-MMU-167044|reactome:R-MMU-179812|reactome:R-MMU-180292|reactome:R-MMU-180336|reactome:R-MMU-182971|reactome:R-MMU-186763|reactome:R-MMU-1963640|reactome:R-MMU-1963642|reactome:R-MMU-2029482|reactome:R-MMU-210993|reactome:R-MMU-2179392|reactome:R-MMU-2424491|reactome:R-MMU-2428933|reactome:R-MMU-2730905|reactome:R-MMU-2871796|reactome:R-MMU-2871809|reactome:R-MMU-354194|reactome:R-MMU-375165|reactome:R-MMU-388841|reactome:R-MMU-389359|reactome:R-MMU-391160|reactome:R-MMU-5654688|reactome:R-MMU-5654689|reactome:R-MMU-5654693|reactome:R-MMU-5654695|reactome:R-MMU-5654699|reactome:R-MMU-5654700|reactome:R-MMU-5654704|reactome:R-MMU-5654706|reactome:R-MMU-5654710|reactome:R-MMU-5654712|reactome:R-MMU-5654719|reactome:R-MMU-5654720|reactome:R-MMU-5654726|reactome:R-MMU-5654727|reactome:R-MMU-5654732|reactome:R-MMU-5654733|reactome:R-MMU-5663213|reactome:R-MMU-5673001|reactome:R-MMU-6807004|reactome:R-MMU-6811558|reactome:R-MMU-74749|reactome:R-MMU-74751|reactome:R-MMU-8851805|reactome:R-MMU-8851907|reactome:R-MMU-8853659|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8865999|reactome:R-MMU-8875555|reactome:R-MMU-8875656|reactome:R-MMU-8983432|reactome:R-MMU-9027284|reactome:R-MMU-9028731|reactome:R-MMU-912526|reactome:R-MMU-912631|reactome:R-MMU-9607240|reactome:R-MMU-9674555|reactome:R-MMU-983695	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:0Zuj4toqaPeuo3snXLa7fckMXU410090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P68040	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-296749|ensembl:ENSMUSP00000020640|uniprotkb:P25388|uniprotkb:P99049|intact:EBI-1183965|uniprotkb:Q3THP0|uniprotkb:Q3THY7|uniprotkb:Q3TKQ0|uniprotkb:Q3TW88|uniprotkb:Q5NCC5|uniprotkb:Q5NCC6|uniprotkb:Q9CSQ0|uniprotkb:Q9ERM6	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:rack1_mouse(display_long)|uniprotkb:p205(gene name synonym)|uniprotkb:Receptor of activated protein kinase C 1(gene name synonym)|uniprotkb:12-3(gene name synonym)|uniprotkb:Gnb2-rs1(gene name synonym)|uniprotkb:Gnb2l1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-2-like 1(gene name synonym)|uniprotkb:Rack1(gene name)|psi-mi:Rack1(display_short)|uniprotkb:Receptor for activated C kinase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1990630"(IRE1-RACK1-PP2A complex)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000543"(positive regulation of gastrulation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P68040|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5626978|go:"GO:0072344"(rescue of stalled ribosome)|ensembl:ENSMUSG00000020372(gene)|ensembl:ENSMUST00000020640(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0008104"(protein localization)|go:"GO:0008200"(ion channel inhibitor activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030292"(protein tyrosine kinase inhibitor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0006412"(translation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043473"(pigmentation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0044297"(cell body)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071363"(cellular response to growth factor stimulus)|refseq:NP_032169.1	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:LXHlhPtxUzHJNncoPteGw2iXsFg10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P62880	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-356951|uniprotkb:P11016|uniprotkb:P54312|ensembl:ENSMUSP00000031726|ensembl:ENSMUSP00000129353	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:gbb2_mouse(display_long)|uniprotkb:Gnb2(gene name)|psi-mi:Gnb2(display_short)|uniprotkb:Transducin beta chain 2(gene name synonym)|uniprotkb:G protein subunit beta-2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_034442.1|refseq:XP_006504616.1|ensembl:ENSMUSG00000029713(gene)|ensembl:ENSMUST00000031726(transcript)|ensembl:ENSMUST00000150063(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043209"(myelin sheath)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051020"(GTPase binding)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P62880|reactome:R-MMU-1296041|reactome:R-MMU-202040|reactome:R-MMU-381676|reactome:R-MMU-392170|reactome:R-MMU-392451|reactome:R-MMU-392851|reactome:R-MMU-400042|reactome:R-MMU-4086398|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-418217|reactome:R-MMU-418555|reactome:R-MMU-418592|reactome:R-MMU-418594|reactome:R-MMU-418597|reactome:R-MMU-420092|reactome:R-MMU-428930|reactome:R-MMU-432040|reactome:R-MMU-456926|reactome:R-MMU-500657|reactome:R-MMU-6814122|reactome:R-MMU-8964315|reactome:R-MMU-8964616|reactome:R-MMU-9009391|reactome:R-MMU-997272	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:dingPUxdpAhe7UMLquv0eqXNtUM10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P62874	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-357152|ensembl:ENSMUSP00000030940|ensembl:ENSMUSP00000101241|ensembl:ENSMUSP00000130123|ensembl:ENSMUSP00000135091|uniprotkb:P04901|uniprotkb:P04697	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:gbb1_mouse(display_long)|uniprotkb:Gnb1(gene name)|psi-mi:Gnb1(display_short)|uniprotkb:Transducin beta chain 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000029064(gene)|ensembl:ENSMUST00000030940(transcript)|ensembl:ENSMUST00000105616(transcript)|ensembl:ENSMUST00000165335(transcript)|ensembl:ENSMUST00000176637(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007603"(phototransduction, visible light)|reactome:R-MMU-9009391|reactome:R-MMU-997272|reactome:R-MMU-8964616|go:"GO:0010659"(cardiac muscle cell apoptotic process)|go:"GO:0030425"(dendrite)|go:"GO:0008283"(cell population proliferation)|go:"GO:0030507"(spectrin binding)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0042622"(photoreceptor outer segment membrane)|go:"GO:0043209"(myelin sheath)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047391"(alkylglycerophosphoethanolamine phosphodiesterase activity)|go:"GO:0050909"(sensory perception of taste)|go:"GO:0051020"(GTPase binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P62874|rcsb pdb:6K41|rcsb pdb:6K42|rcsb pdb:6RMV|reactome:R-MMU-1296041|reactome:R-MMU-202040|reactome:R-MMU-2485179|reactome:R-MMU-381676|reactome:R-MMU-381753|reactome:R-MMU-392170|reactome:R-MMU-392451|reactome:R-MMU-392851|reactome:R-MMU-400042|reactome:R-MMU-4086398|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-418217|reactome:R-MMU-418555|reactome:R-MMU-418592|reactome:R-MMU-418594|reactome:R-MMU-418597|reactome:R-MMU-420092|reactome:R-MMU-428930|reactome:R-MMU-432040|reactome:R-MMU-456926|reactome:R-MMU-500657|reactome:R-MMU-6814122|reactome:R-MMU-8964315|refseq:NP_001153488.1|refseq:NP_001153489.1|refseq:NP_032168.1|refseq:XP_017175466.1	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:zP/G70MXiSQpzbyyWFTWrJFQENk10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:E9PVA8	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-4284669|intact:EBI-6908505|uniprotkb:B2RWW6|ensembl:ENSMUSP00000069432	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:gcn1_mouse(display_long)|uniprotkb:Gcn1(gene name)|psi-mi:Gcn1(display_short)|uniprotkb:GCN1 eIF-2-alpha kinase activator homolog(gene name synonym)|uniprotkb:GCN1-like protein 1(gene name synonym)|uniprotkb:Gcn1l1(gene name synonym)|uniprotkb:General control of amino-acid synthesis 1-like protein 1(gene name synonym)|uniprotkb:Translational activator GCN1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_766307.2|ensembl:ENSMUSG00000041638(gene)|ensembl:ENSMUST00000064454(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006417"(regulation of translation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0043022"(ribosome binding)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR033173|interpro:IPR034085|mint:E9PVA8	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:KX5ViHlt2ZOUAv/9GRSRAMijpE010090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q7TPM6	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-26611378|ensembl:ENSMUSP00000011733|uniprotkb:Q3UNE6	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:fsd1_mouse(display_long)|uniprotkb:Fsd1(gene name)|psi-mi:Fsd1(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000011589(gene)|ensembl:ENSMUST00000011733(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005874"(microtubule)|go:"GO:0007049"(cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051302"(regulation of cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003649(B-box, C-terminal)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017903|interpro:IPR035742|interpro:IPR036116|interpro:IPR043136|mint:Q7TPM6|refseq:NP_899001.1	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:sX9MNhIQcM4Ef8EmufuudJKz2oY10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q148V8	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-4282953|uniprotkb:Q8BZF6|uniprotkb:Q8CI79|uniprotkb:Q8R5C2|uniprotkb:Q8R5D0|ensembl:ENSMUSP00000059839|ensembl:ENSMUSP00000126453	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:fa83h_mouse(display_long)|uniprotkb:Fam83h(gene name)|psi-mi:Fam83h(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001161725.1|refseq:NP_598848.2|refseq:XP_006520300.1|ensembl:ENSMUSG00000046761(gene)|ensembl:ENSMUST00000060807(transcript)|ensembl:ENSMUST00000170153(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007165"(signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0044380"(protein localization to cytoskeleton)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:1990254"(keratin filament binding)|interpro:IPR012461(Protein of unknown function DUF1669)|interpro:IPR041996|mint:Q148V8|refseq:XP_006520299.2	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:3NLWjiNTj+wG44iNYtr/1ghJDu410090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:O35250	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-775332|uniprotkb:Q8K121|ensembl:ENSMUSP00000021147	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:exoc7_mouse(display_long)|uniprotkb:Exocyst complex component Exo70(gene name synonym)|uniprotkb:Exoc7(gene name)|psi-mi:Exoc7(display_short)|uniprotkb:Exo70(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001156344.1|refseq:NP_058553.2|ensembl:ENSMUSG00000020792(gene)|ensembl:ENSMUST00000021147(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0032584"(growth cone membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0090543"(Flemming body)|go:"GO:2000535"(regulation of entry of bacterium into host cell)|interpro:IPR004140(Exo70 exocyst complex subunit)|interpro:IPR016159(Cullin repeat-like)|mint:O35250|rcsb pdb:2PFT|reactome:R-MMU-264876|reactome:R-MMU-5620916	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:kEv82Hc0gyiHJblL7yEpww0Th6o10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:O08579	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-3043874|ensembl:ENSMUSP00000002029|uniprotkb:Q3TIH6|uniprotkb:Q3UJP3	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:emd_mouse(display_long)|uniprotkb:Emd(gene name)|psi-mi:Emd(display_short)|uniprotkb:Sta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000001964(gene)|ensembl:ENSMUST00000002029(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR034989|interpro:IPR035004|mint:O08579|reactome:R-MMU-4419969|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013408|reactome:R-MMU-9013423|reactome:R-MMU-9609523|go:"GO:0031616"(spindle pole centrosome)|refseq:NP_031953.1	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:Zw6awIQkodBfj6LHWEV9HpK8+VY10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:O70194	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-773893|uniprotkb:Q8BLH0|uniprotkb:Q8BWW1|ensembl:ENSMUSP00000098053	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:eif3d_mouse(display_long)|uniprotkb:Eif3s7(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 7(gene name synonym)|uniprotkb:eIF-3-zeta(gene name synonym)|uniprotkb:eIF3 p66(gene name synonym)|uniprotkb:Eif3d(gene name)|psi-mi:Eif3d(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_061219.2|refseq:XP_006521255.1|ensembl:ENSMUSG00000016554(gene)|ensembl:ENSMUST00000100484(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR007783(Eukaryotic translation initiation factor 3, subunit 7)|mint:O70194|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:3AScEAsTKzZ+lSa6oU8pPy6UxgM10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q61749	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-26611340|ensembl:ENSMUSP00000076875|uniprotkb:Q3TYW7|uniprotkb:Q61748|uniprotkb:Q8VC35	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:ei2bd_mouse(display_long)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit delta(gene name synonym)|uniprotkb:Eif2b4(gene name)|psi-mi:Eif2b4(display_short)|uniprotkb:Eif2b(gene name synonym)|uniprotkb:Eif2bd(gene name synonym)|uniprotkb:Jgr1a(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0009408"(response to heat)|go:"GO:0009749"(response to glucose)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0042552"(myelination)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042529|mint:Q61749|reactome:R-MMU-72731|ensembl:ENSMUSG00000029145(gene)|ensembl:ENSMUST00000077693(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0003743"(translation initiation factor activity)|refseq:NP_001120827.1|refseq:NP_001120828.1|refseq:NP_034252.2	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:DoX84q/fy6k/K6rNNo96Xdgc8Kw10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P58252	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-773856|uniprotkb:Q544E4|ensembl:ENSMUSP00000046101	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:ef2_mouse(display_long)|uniprotkb:Eef2(gene name)|psi-mi:Eef2(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_031933.1|ensembl:ENSMUSG00000034994(gene)|ensembl:ENSMUST00000047864(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002931"(response to ischemia)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006414"(translational elongation)|go:"GO:0007568"(aging)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016235"(aggresome)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051593"(response to folic acid)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|mint:P58252|reactome:R-MMU-156902|reactome:R-MMU-5358493|reactome:R-MMU-6798695	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:910/vo3IRjcncyPD4f43dPtS83o10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P10126	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-773865|uniprotkb:Q61511|uniprotkb:Q6ZWN2|uniprotkb:Q8BMB8|uniprotkb:Q8BVS8|uniprotkb:Q99KU5|ensembl:ENSMUSP00000042457	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:ef1a1_mouse(display_long)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Eef1a1(gene name)|psi-mi:Eef1a1(display_short)|uniprotkb:Eef1a(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	dip:DIP-46609N|refseq:NP_034236.2|ensembl:ENSMUSG00000037742(gene)|ensembl:ENSMUST00000042235(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P10126|reactome:R-MMU-156842|reactome:R-MMU-3371511|reactome:R-MMU-6798695|reactome:R-MMU-8876725	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:85G9Uje743KzA02bB/rmKuq2HbU10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9JHU4	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-645061|uniprotkb:E9QM71|ensembl:ENSMUSP00000018851	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:dyhc1_mouse(display_long)|uniprotkb:Dhc1(gene name synonym)|uniprotkb:Dyhc(gene name synonym)|uniprotkb:Cytoplasmic dynein heavy chain 1(gene name synonym)|uniprotkb:Dynein heavy chain, cytosolic(gene name synonym)|uniprotkb:Dync1h1(gene name)|psi-mi:Dync1h1(display_short)|uniprotkb:Dnch1(gene name synonym)|uniprotkb:Dnchc1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_084514.2|ensembl:ENSMUSG00000018707(gene)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002177"(manchette)|go:"GO:0003341"(cilium movement)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007097"(nuclear migration)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008569"(minus-end-directed microtubule motor activity)|go:"GO:0030175"(filopodium)|go:"GO:0030286"(dynein complex)|go:"GO:0030424"(axon)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051301"(cell division)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072382"(minus-end-directed vesicle transport along microtubule)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004273(Dynein heavy chain)|interpro:IPR013594(Dynein heavy chain, N-terminal region 1)|interpro:IPR013602(Dynein heavy chain, N-terminal region 2)|interpro:IPR024317|interpro:IPR024743|interpro:IPR027417|interpro:IPR035699|interpro:IPR035706|interpro:IPR041228|interpro:IPR041466|interpro:IPR041658|ensembl:ENSMUST00000018851(transcript)|interpro:IPR042222|interpro:IPR042228|interpro:IPR043157|interpro:IPR043160|interpro:IPR042219|mint:Q9JHU4|rcsb pdb:3ERR|rcsb pdb:3J1T|rcsb pdb:3J1U|rcsb pdb:3WUQ|rcsb pdb:5AYH|rcsb pdb:6RZA|rcsb pdb:6RZB|reactome:R-MMU-141444|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-6798695|reactome:R-MMU-6807878|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9646399|reactome:R-MMU-9648025	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:sbED0xqQpe32T7I8ijeS3Xqlx7010090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q8BS45	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-22226773|ensembl:ENSMUSP00000124369	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:ift56_mouse(display_long)|uniprotkb:Ttc26(gene name)|psi-mi:Ttc26(display_short)|uniprotkb:Hop(gene name synonym)|uniprotkb:Ift56(gene name synonym)|uniprotkb:Protein hop-sterile(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 26(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000056832(gene)|ensembl:ENSMUST00000162554(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007286"(spermatid development)|go:"GO:0008594"(photoreceptor cell morphogenesis)|go:"GO:0015031"(protein transport)|go:"GO:0030992"(intraciliary transport particle B)|go:"GO:0035082"(axoneme assembly)|go:"GO:0035720"(intraciliary anterograde transport)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042073"(intraciliary transport)|go:"GO:0046530"(photoreceptor cell differentiation)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0097546"(ciliary base)|go:"GO:0120170"(intraciliary transport particle B binding)|go:"GO:1905198"(manchette assembly)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR030511|mint:Q8BS45|reactome:R-MMU-5620924|refseq:NP_705828.2	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:p2KI2cBHfmwpd4dDL9zp84Jvvo410090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q62158	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-642025|uniprotkb:Q62157|uniprotkb:Q8C2Q5|uniprotkb:Q99LK1|ensembl:ENSMUSP00000021761|ensembl:ENSMUSP00000152730	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:tri27_mouse(display_long)|uniprotkb:Ret finger protein(gene name synonym)|uniprotkb:Tripartite motif-containing protein 27(gene name synonym)|uniprotkb:Trim27(gene name)|psi-mi:Trim27(display_short)|uniprotkb:Rfp(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM27(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_033080.2|refseq:XP_006516669.1|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0045087"(innate immune response)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0016605"(PML body)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051127"(positive regulation of actin nucleation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090281"(negative regulation of calcium ion import)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035791|interpro:IPR043136|mint:Q62158|reactome:R-MMU-3232142|reactome:R-MMU-8948751|ensembl:ENSMUSG00000021326(gene)|ensembl:ENSMUST00000021761(transcript)|ensembl:ENSMUST00000222544(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001650"(fibrillar center)|go:"GO:0002820"(negative regulation of adaptive immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:ay3vOvfbC0rFrDbLB0NsvrT9eBw10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q6P2B1	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-26611660|ensembl:ENSMUSP00000012679|uniprotkb:Q7TSL6|uniprotkb:Q8BKX4|uniprotkb:Q8BP42	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:tnpo3_mouse(display_long)|uniprotkb:Tnpo3(gene name)|psi-mi:Tnpo3(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|mint:Q6P2B1|ensembl:ENSMUSG00000012535(gene)|ensembl:ENSMUST00000012679(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|refseq:NP_001334008.1|refseq:NP_796270.2	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:dMFxZf8VpdN1DbIrtONfZm0MWe010090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9DC40	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1571482|ensembl:ENSMUSP00000024987|ensembl:ENSMUSP00000110835|uniprotkb:Q3U3J5|uniprotkb:Q3UID7|uniprotkb:Q3UP41|uniprotkb:Q8BN03|uniprotkb:Q8C1T3|uniprotkb:Q91VQ3	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:telo2_mouse(display_long)|uniprotkb:Kiaa0683(gene name synonym)|uniprotkb:Telo2(gene name)|psi-mi:Telo2(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000024170(gene)|ensembl:ENSMUST00000024987(transcript)|ensembl:ENSMUST00000115181(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0032006"(regulation of TOR signaling)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1904515"(positive regulation of TORC2 signaling)|interpro:IPR019337|interpro:IPR038528|go:"GO:0034399"(nuclear periphery)|mint:Q9DC40|rcsb pdb:4CKT|rcsb pdb:4CSE|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070209"(ASTRA complex)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|refseq:NP_001157133.1|refseq:NP_082156.2|dip:DIP-60997N	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:do9Vz0DJsTjq0Zi6X2JLVuCmhWU10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q5SVR0	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-11090932|uniprotkb:Q6A019|uniprotkb:Q80ZU6|uniprotkb:Q3UGF5|uniprotkb:Q6PDP2|uniprotkb:Q6P1G9|uniprotkb:Q8C7K9|uniprotkb:Q9CSQ2|uniprotkb:Q8CCW2|uniprotkb:Q8CBR7|ensembl:ENSMUSP00000098828	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:tbc9b_mouse(display_long)|uniprotkb:Tbc1d9b(gene name)|psi-mi:Tbc1d9b(display_short)|uniprotkb:Kiaa0676(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001277688.1|refseq:NP_001277689.1|refseq:NP_084021.2|ensembl:ENSMUSG00000036644(gene)|ensembl:ENSMUST00000101270(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR004182(GRAM)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035969|interpro:IPR036014|interpro:IPR036017|mint:Q5SVR0	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:rhD3sO4fOuxc2zfdIGJ1cuR40Sk10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q6ZWR6	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-10760754|uniprotkb:Q8K3T7|uniprotkb:Q9ERT7|uniprotkb:Q9ERT8	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:syne1_mouse(display_long)|uniprotkb:Synaptic nuclear envelope protein 1(gene name synonym)|uniprotkb:Enaptin(gene name synonym)|uniprotkb:Myocyte nuclear envelope protein 1(gene name synonym)|uniprotkb:Nuclear envelope spectrin repeat protein 1(gene name synonym)|uniprotkb:Syne1(gene name)|psi-mi:Syne1(display_short)|uniprotkb:KASH domain-containing protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	mint:Q6ZWR6|refseq:NP_001073154.1|go:"GO:0000932"(P-body)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005819"(spindle)|go:"GO:0007030"(Golgi organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030496"(midbody)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051642"(centrosome localization)|go:"GO:0061886"(negative regulation of mini excitatory postsynaptic potential)|go:"GO:0090292"(nuclear matrix anchoring at nuclear membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|go:"GO:1902017"(regulation of cilium assembly)|go:"GO:1903353"(regulation of nucleus organization)|go:"GO:2001054"(negative regulation of mesenchymal cell apoptotic process)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR012315(Klarsicht/ANC-1/syne-1 homology)|interpro:IPR018159|interpro:IPR036872|dip:DIP-60966N	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:96Ke3lpwOXQNnVBWVhwJaEpeNAM10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9JI11	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-1181352|ensembl:ENSMUSP00000018353	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:stk4_mouse(display_long)|uniprotkb:STE20-like kinase MST1(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 1(gene name synonym)|uniprotkb:Stk4(gene name)|psi-mi:Stk4(display_short)|uniprotkb:Mst1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_067395.1|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051262"(protein tetramerization)|go:"GO:0060215"(primitive hemopoiesis)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0060800"(regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024205|interpro:IPR036674|mint:Q9JI11|reactome:R-MMU-2028269|ensembl:ENSMUSG00000018209(gene)|ensembl:ENSMUST00000018353(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001841"(neural tube formation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003157"(endocardium development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:aBZlhLOr5bIFz03KD7VAeKm1nnU10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q91VJ4	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2527046|ensembl:ENSMUSP00000009138|ensembl:ENSMUSP00000113657|ensembl:ENSMUSP00000156711	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:stk38_mouse(display_long)|uniprotkb:Stk38(gene name)|psi-mi:Stk38(display_short)|uniprotkb:Ndr1(gene name synonym)|uniprotkb:NDR1 protein kinase(gene name synonym)|uniprotkb:Nuclear Dbf2-related kinase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0000287"(magnesium ion binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|mint:Q91VJ4|reactome:R-MMU-9013418|reactome:R-MMU-9013422|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensembl:ENSMUSG00000024006(gene)|ensembl:ENSMUST00000009138(transcript)|ensembl:ENSMUST00000119274(transcript)|ensembl:ENSMUST00000232836(transcript)|refseq:NP_598876.1	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:TvwVb4eUVw+H1smxX4+Z3LjcAUw10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9JI10	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-4285880|uniprotkb:Q60877|uniprotkb:Q80UG4|uniprotkb:Q8CI58|ensembl:ENSMUSP00000018476	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:stk3_mouse(display_long)|uniprotkb:Mst2(gene name synonym)|uniprotkb:Stk3(gene name)|psi-mi:Stk3(display_short)|uniprotkb:Mess1(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 2(gene name synonym)|uniprotkb:STE20-like kinase MST2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_062609.2|ensembl:ENSMUSG00000022329(gene)|ensembl:ENSMUST00000018476(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001841"(neural tube formation)|go:"GO:0003157"(endocardium development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060215"(primitive hemopoiesis)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0060800"(regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024205|interpro:IPR036674|mint:Q9JI10|reactome:R-MMU-2028269|dip:DIP-61760N	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:F1GEMB9TES32FDkAIPtuXIxbEoI10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q3TAA7	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-26611639|ensembl:ENSMUSP00000027414|ensembl:ENSMUSP00000109182|uniprotkb:Q6P7J8|uniprotkb:Q9DBT7	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:s11ip_mouse(display_long)|uniprotkb:LKB1-interacting protein 1(gene name synonym)|uniprotkb:Stk11ip(gene name)|psi-mi:Stk11ip(display_short)|uniprotkb:Lip1(gene name synonym)|uniprotkb:Lkb1ip(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000026213(gene)|ensembl:ENSMUST00000027414(transcript)|ensembl:ENSMUST00000113553(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0008104"(protein localization)|go:"GO:0019901"(protein kinase binding)|interpro:IPR031782|interpro:IPR032675|mint:Q3TAA7|reactome:R-MMU-6798695|refseq:NP_082162.3	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:5ExA83um1Q6DN1tB6fgO6GczBkA10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q60988	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-16417888|uniprotkb:Q80VK7|uniprotkb:Q8C7U6|uniprotkb:Q8CEL7|uniprotkb:Q99KL4	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:stil_mouse(display_long)|uniprotkb:Stil(gene name)|psi-mi:Stil(display_short)|uniprotkb:Sil(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	go:"GO:0000578"(embryonic axis specification)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0021915"(neural tube development)|go:"GO:0030900"(forebrain development)|go:"GO:0030903"(notochord development)|go:"GO:0033504"(floor plate development)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0051298"(centrosome duplication)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:1905515"(non-motile cilium assembly)|refseq:NP_033211.2|interpro:IPR026123|mint:Q60988	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:bGCfYFY42kuGQ+eN0kysiO6FU4U10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q62186	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-11568249|ensembl:ENSMUSP00000002090	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:ssrd_mouse(display_long)|uniprotkb:Signal sequence receptor subunit delta(gene name synonym)|uniprotkb:Ssr4(gene name)|psi-mi:Ssr4(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_033305.1|ensembl:ENSMUSG00000002014(gene)|ensembl:ENSMUST00000002090(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008855(Translocon-associated)|mint:Q62186	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:4gupEFkrX+TomW/+FEpKtmKcfWU10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:O54781	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-593325|uniprotkb:Q8VCD9	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:srpk2_mouse(display_long)|uniprotkb:Serine/arginine-rich protein-specific kinase 2(gene name synonym)|uniprotkb:SFRS protein kinase 2(gene name synonym)|uniprotkb:Srpk2(gene name)|psi-mi:Srpk2(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	mint:O54781|refseq:NP_033300.2|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|refseq:XP_017176258.1|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000785"(chromatin)|go:"GO:0001525"(angiogenesis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0035063"(nuclear speck organization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0062176"(R-loop disassembly)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:w16BWU5PrwNUPMC4Yw83eDldbrA10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q62261	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-397843|ensembl:ENSMUSP00000006629|ensembl:ENSMUSP00000011877|uniprotkb:A2AFU1|uniprotkb:Q3TEM7|uniprotkb:Q5SQL8|uniprotkb:Q5SQL9|uniprotkb:Q9QWJ7	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:sptb2_mouse(display_long)|uniprotkb:Sptbn1(gene name)|psi-mi:Sptbn1(display_short)|uniprotkb:Spnb-2(gene name synonym)|uniprotkb:Spnb2(gene name synonym)|uniprotkb:Sptb2(gene name synonym)|uniprotkb:Beta-II spectrin(gene name synonym)|uniprotkb:Fodrin beta chain(gene name synonym)|uniprotkb:Embryonic liver fodrin(gene name synonym)|uniprotkb:Elf(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000020315(gene)|ensembl:ENSMUST00000006629(transcript)|ensembl:ENSMUST00000011877(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008091"(spectrin)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030673"(axolemma)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031430"(M band)|go:"GO:0032437"(cuticular plate)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0071709"(membrane assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|interpro:IPR041681|mint:Q62261|rcsb pdb:1BTN|rcsb pdb:1MPH|rcsb pdb:6M3P|reactome:R-MMU-375165|reactome:R-MMU-445095|reactome:R-MMU-5673001|reactome:R-MMU-6807878|reactome:R-MMU-9013420|reactome:R-MMU-9013424|refseq:NP_033286.2|refseq:NP_787030.2|refseq:XP_006514662.1|refseq:XP_006514663.1|dip:DIP-31558N	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:N6xVFU+ocY6PXsIz5ZIsA05bGPs10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P16546	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-911063|uniprotkb:A3KGU6|uniprotkb:Q8K380|uniprotkb:Q9CT05|uniprotkb:A3KGU8|ensembl:ENSMUSP00000092697	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:sptn1_mouse(display_long)|uniprotkb:Alpha-II spectrin(gene name synonym)|uniprotkb:Fodrin alpha chain(gene name synonym)|uniprotkb:Sptan1(gene name)|psi-mi:Sptan1(display_short)|uniprotkb:Spna2(gene name synonym)|uniprotkb:Spta2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	dip:DIP-37712N|ensembl:ENSMUSG00000057738(gene)|ensembl:ENSMUST00000095083(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005916"(fascia adherens)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030018"(Z disc)|go:"GO:0030507"(spectrin binding)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032437"(cuticular plate)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033270"(paranode region of axon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051693"(actin filament capping)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035825|interpro:IPR036028|mint:P16546|reactome:R-MMU-264870|reactome:R-MMU-375165|reactome:R-MMU-445095|reactome:R-MMU-5673001|reactome:R-MMU-6798695|reactome:R-MMU-6807878|reactome:R-MMU-9013420|reactome:R-MMU-9013424	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:UVB6Kv+PBlqDH3OLoGjxm5oYVPQ10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9D3S3	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-26611621|ensembl:ENSMUSP00000138025|uniprotkb:Q8K050	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:snx29_mouse(display_long)|uniprotkb:Snx29(gene name)|psi-mi:Snx29(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000071669(gene)|go:"GO:0035091"(phosphatidylinositol binding)|interpro:IPR001683(Phox-like)|interpro:IPR004012(RUN)|interpro:IPR036871|interpro:IPR037213|interpro:IPR037916|mint:Q9D3S3|ensembl:ENSMUST00000180792(transcript)|refseq:NP_001277077.1|refseq:NP_083240.2	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:ZdREd44wk4bHUehX4VuHq/XulrQ10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q6P4T2	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-6878408|ensembl:ENSMUSP00000099509|uniprotkb:Q69ZZ3	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:u520_mouse(display_long)|uniprotkb:Snrnp200(gene name)|psi-mi:Snrnp200(display_short)|uniprotkb:Kiaa0788(gene name synonym)|uniprotkb:BRR2 homolog(gene name synonym)|uniprotkb:U5 snRNP-specific 200 kDa protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000003660(gene)|ensembl:ENSMUST00000103220(transcript)|go:"GO:0000388"("spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)")|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0042802"(identical protein binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|interpro:IPR041094|mint:Q6P4T2|reactome:R-MMU-72163|reactome:R-MMU-72165|refseq:NP_796188.2	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:P0APWhAjy05E6VYhOWEmHdw2QHw10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q8CG47	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-6921575|ensembl:ENSMUSP00000047872|uniprotkb:Q8BTS7|uniprotkb:Q8BTY9|uniprotkb:Q99K21	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:smc4_mouse(display_long)|uniprotkb:Smc4(gene name)|psi-mi:Smc4(display_short)|uniprotkb:Capc(gene name synonym)|uniprotkb:Smc4l1(gene name synonym)|uniprotkb:Chromosome-associated polypeptide C(gene name synonym)|uniprotkb:XCAP-C homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:XP_006502109.1|ensembl:ENSMUSG00000034349(gene)|ensembl:ENSMUST00000042901(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0016607"(nuclear speck)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051383"(kinetochore organization)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041738|mint:Q8CG47|rcsb pdb:3L51|reactome:R-MMU-2299718|reactome:R-MMU-2514853|refseq:NP_598547.1	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:SF4vyf1kJkH5VuPPgdXoHrPCxaA10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9CW03	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2550068|ensembl:ENSMUSP00000025930|uniprotkb:O35667|uniprotkb:Q9QUS3	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:smc3_mouse(display_long)|uniprotkb:Smc3(gene name)|psi-mi:Smc3(display_short)|uniprotkb:Bam(gene name synonym)|uniprotkb:Bmh(gene name synonym)|uniprotkb:Cspg6(gene name synonym)|uniprotkb:Mmip1(gene name synonym)|uniprotkb:Smc3l1(gene name synonym)|uniprotkb:Smcd(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 6(gene name synonym)|uniprotkb:Chromosome segregation protein SmcD(gene name synonym)|uniprotkb:Basement membrane-associated chondroitin proteoglycan(gene name synonym)|uniprotkb:Mad member-interacting protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000024974(gene)|ensembl:ENSMUST00000025930(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|mint:Q9CW03|rcsb pdb:2WD5|reactome:R-MMU-2467813|reactome:R-MMU-2468052|reactome:R-MMU-2470946|reactome:R-MMU-2500257|reactome:R-MMU-3108214|refseq:NP_031816.2|dip:DIP-57028N	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:9tJqVTJ2k3viYrJVtDfH2TekFIg10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q5U458	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-772487|uniprotkb:A2A8C9|uniprotkb:Q8BP83|uniprotkb:Q8C1Z4|uniprotkb:Q8C6U5|ensembl:ENSMUSP00000051643	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:djc11_mouse(display_long)|uniprotkb:Dnajc11(gene name)|psi-mi:Dnajc11(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_766292.2|ensembl:ENSMUSG00000039768(gene)|ensembl:ENSMUST00000062904(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0042407"(cristae formation)|go:"GO:0061617"(MICOS complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR024586|interpro:IPR036869|mint:Q5U458	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:xu3s2vRdQrZ3EiO2zlKzt2eWJ1010090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:O54946	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-642500|uniprotkb:Q3TE94|uniprotkb:Q3U6L0|uniprotkb:Q3UNJ5|uniprotkb:Q3UYT7|uniprotkb:Q99LA5|uniprotkb:Q9QYI9|ensembl:ENSMUSP00000008733	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:dnjb6_mouse(display_long)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:MRJ(gene name synonym)|uniprotkb:mDj4(gene name synonym)|uniprotkb:Dnajb6(gene name)|psi-mi:Dnajb6(display_short)|uniprotkb:Hsj2(gene name synonym)|uniprotkb:Mrj(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001033029.1|refseq:NP_001120839.1|refseq:NP_035977.2|ensembl:ENSMUSG00000029131(gene)|ensembl:ENSMUST00000008733(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0060717"(chorion development)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0090084"(negative regulation of inclusion body assembly)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:O54946|reactome:R-MMU-3371453	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:Snii+B7COng2Zkduai/v24f83bw10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q99M87	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-647233|uniprotkb:Q8BSM0|uniprotkb:Q99L09|uniprotkb:Q99P71|uniprotkb:Q99P76|uniprotkb:Q9CT11|uniprotkb:Q9DBJ7|uniprotkb:Q9DC44|ensembl:ENSMUSP00000053842	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:dnja3_mouse(display_long)|uniprotkb:Tumorous imaginal discs protein Tid56 homolog(gene name synonym)|uniprotkb:DnaJ protein Tid-1(gene name synonym)|uniprotkb:Dnaja3(gene name)|psi-mi:Dnaja3(display_short)|uniprotkb:Tid1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001128584.1|refseq:NP_076135.3|mint:Q99M87|ensembl:ENSMUSG00000004069(gene)|ensembl:ENSMUST00000060067(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005133"(interferon-gamma receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006457"(protein folding)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007569"(cell aging)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0106137"(IkappaB kinase complex binding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:dBJIJ2BY9vghCDt8+ooQWBFjsRs10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q60997	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-26611291|uniprotkb:Q80YC6|uniprotkb:Q9JMJ9	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:dmbt1_mouse(display_long)|uniprotkb:Apactin(gene name synonym)|uniprotkb:CRP-ductin(gene name synonym)|uniprotkb:Glycoprotein 300(gene name synonym)|uniprotkb:Hensin(gene name synonym)|uniprotkb:Mucin-like glycoprotein(gene name synonym)|uniprotkb:Vomeroglandin(gene name synonym)|uniprotkb:p80(gene name synonym)|uniprotkb:Dmbt1(gene name)|psi-mi:Dmbt1(display_short)|uniprotkb:Crpd(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001824"(blastocyst development)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006952"(defense response)|go:"GO:0009617"(response to bacterium)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030858"(positive regulation of epithelial cell differentiation)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035375"(zymogen binding)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042494"(detection of bacterial lipoprotein)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0043152"(induction of bacterial agglutination)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070891"(lipoteichoic acid binding)|go:"GO:1904399"(heparan sulfate binding)|reactome:R-MMU-5683826|interpro:IPR042235|mint:Q60997|refseq:NP_001334561.1|refseq:NP_031795.2|interpro:IPR000859(CUB)|interpro:IPR035914|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR017448(Speract/scavenger receptor related)|interpro:IPR036772|interpro:IPR001507(Endoglin/CD105 antigen)|interpro:IPR017977	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:vAEcTEFtsiAO+xFoZncFHO2vePI10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:O08788	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-776180|uniprotkb:E9QLJ1|uniprotkb:Q3TZG7|ensembl:ENSMUSP00000109552	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:dctn1_mouse(display_long)|uniprotkb:150 kDa dynein-associated polypeptide(gene name synonym)|uniprotkb:DAP-150(gene name synonym)|uniprotkb:p150-glued(gene name synonym)|uniprotkb:Dctn1(gene name)|psi-mi:Dctn1(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_031861.2|dip:DIP-32057N|ensembl:ENSMUSG00000031865(gene)|ensembl:ENSMUST00000113919(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005938"(cell cortex)|go:"GO:0007097"(nuclear migration)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008017"(microtubule binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021517"(ventral spinal cord development)|go:"GO:0030424"(axon)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0032402"(melanosome transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045171"(intercellular bridge)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061744"(motor behavior)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0099738"(cell cortex region)|go:"GO:0120103"(centriolar subdistal appendage)|go:"GO:1904398"(positive regulation of neuromuscular junction development)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990535"(neuron projection maintenance)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR022157|interpro:IPR036859|mint:O08788|reactome:R-MMU-2132295|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6807878|reactome:R-MMU-6811436|reactome:R-MMU-8854518	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:pqj7TtNDgexEbxqLwksW3eW41bo10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9ERK4	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-400836|intact:EBI-4283823|ensembl:ENSMUSP00000002790	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:xpo2_mouse(display_long)|uniprotkb:Cse1l(gene name)|psi-mi:Cse1l(display_short)|uniprotkb:Importin-alpha re-exporter(gene name synonym)|uniprotkb:Chromosome segregation 1-like protein(gene name synonym)|uniprotkb:Xpo2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_076054.1|ensembl:ENSMUSG00000002718(gene)|ensembl:ENSMUST00000002790(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR005043(CAS/CSE, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:Q9ERK4	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:vJpTu+2YjwIRrjM3V815K3lZzAg10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9QXK3	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-21287612|ensembl:ENSMUSP00000038368|uniprotkb:A6H6J5|uniprotkb:Q3TQD5|uniprotkb:Q3UEL6|uniprotkb:Q8C2J6	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:copg2_mouse(display_long)|uniprotkb:Copg2(gene name)|psi-mi:Copg2(display_short)|uniprotkb:Gamma-2-coat protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000025607(gene)|ensembl:ENSMUST00000048774(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0009306"(protein secretion)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030426"(growth cone)|go:"GO:0072384"(organelle transport along microtubule)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013040(Coatomer, gamma subunit, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017106(Coatomer, gamma subunit)|interpro:IPR032154|interpro:IPR037067|mint:Q9QXK3|reactome:R-MMU-6807878|reactome:R-MMU-6811434|refseq:NP_059506.1	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:DEQGirBT9URbx4HIfXTFHtAFjm410090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q8CIE6	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-644254|uniprotkb:E9Q075|ensembl:ENSMUSP00000118179	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:copa_mouse(display_long)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:Copa(gene name)|psi-mi:Copa(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_034068.3|ensembl:ENSMUSG00000026553(gene)|ensembl:ENSMUST00000135192(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003729"(mRNA binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030157"(pancreatic juice secretion)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0044297"(cell body)|go:"GO:0099612"(protein localization to axon)|go:"GO:1902463"(protein localization to cell leading edge)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011048(Cytochrome cd1-nitrite reductase-like, C-terminal haem d1)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR024977|interpro:IPR036322|mint:Q8CIE6|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-MMU-6807878|reactome:R-MMU-6811434	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:c+/zgZ1/6rEy0vlikp+E+4gijto10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q61189	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-13644126	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:icln_mouse(display_long)|uniprotkb:Clns1a(gene name)|psi-mi:Clns1a(display_short)|uniprotkb:Clci(gene name synonym)|uniprotkb:Clcni(gene name synonym)|uniprotkb:Chloride channel, nucleotide sensitive 1A(gene name synonym)|uniprotkb:Chloride conductance regulatory protein ICln(gene name synonym)|uniprotkb:Chloride ion current inducer protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0045794"(negative regulation of cell volume)|reactome:R-MMU-191859|interpro:IPR003521(Nucleotide-sensitive chloride conductance regulator)|interpro:IPR011993(Pleckstrin homology-type)|mint:Q61189|interpro:IPR039924	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:gGnMU2gNjbiZqK4dhmZ7wWaCiX410090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q99KN2	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-4283601|uniprotkb:Q9DCZ7|ensembl:ENSMUSP00000003759	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:ciao1_mouse(display_long)|uniprotkb:Ciao1(gene name)|psi-mi:Ciao1(display_short)|uniprotkb:Wdr39(gene name synonym)|uniprotkb:WD repeat-containing protein 39(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_079572.2|ensembl:ENSMUSG00000003662(gene)|ensembl:ENSMUST00000003759(transcript)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:Q99KN2	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:zIBtbbwc4hWRw+uGBN5090nQ1Nk10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q6A065	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-2554140|uniprotkb:Q7TQD9|uniprotkb:Q8BJW2|uniprotkb:Q9D3Z0|ensembl:ENSMUSP00000141793	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:ce170_mouse(display_long)|uniprotkb:Kiaa0470(gene name synonym)|uniprotkb:Cep170(gene name)|psi-mi:Cep170(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000057335(gene)|ensembl:ENSMUST00000194727(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0072686"(mitotic spindle)|go:"GO:0120103"(centriolar subdistal appendage)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR026644|interpro:IPR029300|mint:Q6A065|refseq:XP_006497000.1	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:gawEp+b6DVpUroRU0JHmHzo7qPg10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q99LM2	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-776255|uniprotkb:Q3UE41|ensembl:ENSMUSP00000099441	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:ck5p3_mouse(display_long)|uniprotkb:Cdk5rap3(gene name)|psi-mi:Cdk5rap3(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_084524.1|ensembl:ENSMUSG00000018669(gene)|ensembl:ENSMUST00000103152(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0001889"(liver development)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010921"(regulation of phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030262"(apoptotic nuclear changes)|go:"GO:0030332"(cyclin binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0060318"(definitive erythrocyte differentiation)|go:"GO:0071569"(protein ufmylation)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1903363"(negative regulation of cellular protein catabolic process)|interpro:IPR008491(Protein of unknown function DUF773)|mint:Q99LM2	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:N2HLQbkEI096yRYkU3BDfxKjD7k10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P11440	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-846949|uniprotkb:Q3TI12|uniprotkb:P70337|ensembl:ENSMUSP00000020099|ensembl:ENSMUSP00000113184	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:cdk1_mouse(display_long)|uniprotkb:p34 protein kinase(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym)|uniprotkb:Cdk1(gene name)|psi-mi:Cdk1(display_short)|uniprotkb:Cdc2a(gene name synonym)|uniprotkb:Cdc2(gene name synonym)|uniprotkb:Cell division control protein 2 homolog(gene name synonym)|uniprotkb:Cdkn1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_031685.2|dip:DIP-38725N|ensembl:ENSMUSG00000019942(gene)|ensembl:ENSMUST00000020099(transcript)|ensembl:ENSMUST00000119827(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007569"(cell aging)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030332"(cyclin binding)|go:"GO:0030496"(midbody)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0035173"(histone kinase activity)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045471"(response to ethanol)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048511"(rhythmic process)|go:"GO:0051301"(cell division)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0097125"(cyclin B1-CDK1 complex)|go:"GO:0097472"(cyclin-dependent protein kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P11440|reactome:R-MMU-110056|reactome:R-MMU-174048|reactome:R-MMU-174184|reactome:R-MMU-176408|reactome:R-MMU-176412|reactome:R-MMU-176417|reactome:R-MMU-2299718|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-2980767|reactome:R-MMU-2995383|reactome:R-MMU-3301854|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-4419969|reactome:R-MMU-5620912|reactome:R-MMU-5687128|reactome:R-MMU-5689896|reactome:R-MMU-6804114|reactome:R-MMU-6804757|reactome:R-MMU-68875|reactome:R-MMU-69273|reactome:R-MMU-69478|reactome:R-MMU-75035|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8878166	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:YLS0FzcbPcyxmR3rOh2IJxdPNn010090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9Z0H0	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-26611250|ensembl:ENSMUSP00000031221|ensembl:ENSMUSP00000113385|uniprotkb:Q9WUV1|uniprotkb:Q9Z2Y7	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:cdc7_mouse(display_long)|uniprotkb:Cdc7(gene name)|psi-mi:Cdc7(display_short)|uniprotkb:Cdc7l1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000029283(gene)|ensembl:ENSMUST00000031221(transcript)|ensembl:ENSMUST00000118261(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0045171"(intercellular bridge)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q9Z0H0|reactome:R-MMU-176187|reactome:R-MMU-68962|refseq:NP_001258495.1|refseq:NP_001258496.1|refseq:NP_001258497.1|refseq:NP_033993.2	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:Hy93bDhzF09mVm+q/TFsCQ3EX3w10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P80318	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-772361|ensembl:ENSMUSP00000001452	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:tcpg_mouse(display_long)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:Matricin(gene name synonym)|uniprotkb:mTRiC-P5(gene name synonym)|uniprotkb:Cct3(gene name)|psi-mi:Cct3(display_short)|uniprotkb:Cctg(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_033966.1|dip:DIP-32344N|ensembl:ENSMUSG00000001416(gene)|ensembl:ENSMUST00000001452(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P80318|rcsb pdb:1GML|rcsb pdb:1GN1|reactome:R-MMU-390471|reactome:R-MMU-5620922|reactome:R-MMU-6814122	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:+jrWcoDzrkHivHA/h3aApt0gBFU10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:O35887	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-688160|ensembl:ENSMUSP00000031779	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:calu_mouse(display_long)|uniprotkb:Crocalbin(gene name synonym)|uniprotkb:Calu(gene name)|psi-mi:Calu(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_031620.1|ensembl:ENSMUSG00000029767(gene)|ensembl:ENSMUST00000031779(transcript)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0019899"(enzyme binding)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0042470"(melanosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR027239|mint:O35887|reactome:R-MMU-381426|reactome:R-MMU-8957275	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:JSG2x2O/Lpg1JYjpePi+aqwSx+g10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:B2RQC6	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-3043834|ensembl:ENSMUSP00000013773|uniprotkb:B7ZN27	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:pyr1_mouse(display_long)|uniprotkb:Cad(gene name)|psi-mi:Cad(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000013629(gene)|ensembl:ENSMUST00000013773(transcript)|go:"GO:0002134"(UTP binding)|go:"GO:0004070"(aspartate carbamoyltransferase activity)|go:"GO:0004088"("carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity")|go:"GO:0004151"(dihydroorotase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014075"(response to amine)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016597"(amino acid binding)|go:"GO:0017144"|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019240"(citrulline biosynthetic process)|go:"GO:0001889"(liver development)|go:"GO:0031000"(response to caffeine)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051414"(response to cortisol)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|interpro:IPR002082(Aspartate carbamoyltransferase, eukaryotic)|interpro:IPR002195(Dihydroorotase, conserved site)|interpro:IPR002474(Carbamoyl phosphate synthase, small subunit, N-terminal)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR006130(Aspartate/ornithine carbamoyltransferase)|interpro:IPR006131(Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region)|go:"GO:0019899"(enzyme binding)|interpro:IPR006132(Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding)|interpro:IPR006274(Carbamoyl phosphate synthase, small subunit)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011607(MGS-like)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR017926|interpro:IPR029062|interpro:IPR032466|interpro:IPR035686|interpro:IPR036480|interpro:IPR036897|interpro:IPR036901|interpro:IPR036914|mint:B2RQC6|reactome:R-MMU-500753|refseq:NP_076014.1|refseq:NP_001276451.1|dip:DIP-61412N	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:t+qQw7me78vEm/Y4VBBhS8fmCsY10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q8C3R1	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-26611217|ensembl:ENSMUSP00000036016|uniprotkb:Q3TDC8|uniprotkb:Q3U442|uniprotkb:Q6NV65|uniprotkb:Q8C3T3|uniprotkb:Q9JKU7	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:brat1_mouse(display_long)|uniprotkb:BRCA1-associated protein required for ATM activation protein 1(gene name synonym)|uniprotkb:Brat1(gene name)|psi-mi:Brat1(display_short)|uniprotkb:Baat1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000000148(gene)|ensembl:ENSMUST00000041588(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016477"(cell migration)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0051646"(mitochondrion localization)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038904|mint:Q8C3R1|refseq:NP_001263216.1|refseq:NP_851411.1	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:cPEv8+XJBvFerCbwiidGmHKiGH410090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q91YN9	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-4281163|uniprotkb:Q3UMR7|ensembl:ENSMUSP00000042009	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:bag2_mouse(display_long)|uniprotkb:Bag2(gene name)|psi-mi:Bag2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000042215(gene)|ensembl:ENSMUST00000044691(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:Q91YN9|rcsb pdb:3CQX|rcsb pdb:3D0T|reactome:R-MMU-3371453|refseq:NP_663367.1	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:Ml80SWS2aEOQRIzvRwO6yMYOKvM10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P61205	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-444797|uniprotkb:P16587|ensembl:ENSMUSP00000050689	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:arf3_mouse(display_long)|uniprotkb:Arf3(gene name)|psi-mi:Arf3(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_031504.1|refseq:XP_011243747.1|ensembl:ENSMUSG00000051853(gene)|ensembl:ENSMUST00000053183(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P61205|reactome:R-MMU-1660514|reactome:R-MMU-6807878|reactome:R-MMU-6811434	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:np09WjdbXRu9vgMbiXn9EA3ExqA10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9WV76	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-25301240|ensembl:ENSMUSP00000044262|ensembl:ENSMUSP00000075904|uniprotkb:B0V3P2	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:ap4b1_mouse(display_long)|uniprotkb:Adaptor-related protein complex 4 subunit beta-1(gene name synonym)|uniprotkb:Beta subunit of AP-4(gene name synonym)|uniprotkb:Beta4-adaptin(gene name synonym)|uniprotkb:AP-4 adaptor complex subunit beta(gene name synonym)|uniprotkb:Ap4b1(gene name)|psi-mi:Ap4b1(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000032952(gene)|ensembl:ENSMUST00000047285(transcript)|ensembl:ENSMUST00000076599(transcript)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030124"(AP-4 adaptor complex)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030276"(clathrin binding)|go:"GO:0061938"(protein localization to somatodendritic compartment)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|mint:Q9WV76|reactome:R-MMU-432720|reactome:R-MMU-432722|refseq:NP_001157024.1|refseq:NP_080469.2	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:y9xmUX5vxEpwfSNsWDODbQ/ua6Y10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q8VCU0	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-26611197|ensembl:ENSMUSP00000021682|uniprotkb:Q5DU16	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:ange1_mouse(display_long)|uniprotkb:Angel1(gene name)|psi-mi:Angel1(display_short)|uniprotkb:Kiaa0759(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000021257(gene)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR036691|mint:Q8VCU0|ensembl:ENSMUST00000021682(transcript)|refseq:NP_653107.2	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:8ahDbBUZgmuGHo221XJ+6b7Zs0Y10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q70FJ1	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-645887|uniprotkb:Q3TH74|uniprotkb:Q80TR6	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:akap9_mouse(display_long)|uniprotkb:Akap9(gene name)|psi-mi:Akap9(display_short)|uniprotkb:Kiaa0803(gene name synonym)|uniprotkb:Protein kinase A-anchoring protein 9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_919444.2|interpro:IPR019528|interpro:IPR028745|go:"GO:0000242"(pericentriolar material)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007165"(signal transduction)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034629"|go:"GO:0034705"(potassium channel complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044307"(dendritic branch)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060009"(Sertoli cell development)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097729"(9+2 motile cilium)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0120219"(subapical part of cell)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903358"(regulation of Golgi organization)|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5576890|reactome:R-MMU-5576893|reactome:R-MMU-5620912|reactome:R-MMU-8854518|mint:Q70FJ1	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:9yyCeoX35wNULJg413iGM9TIQxA10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9R0L7	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-4285401	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:akp8l_mouse(display_long)|uniprotkb:Akap8l(gene name)|psi-mi:Akap8l(display_short)|uniprotkb:Nakap(gene name synonym)|uniprotkb:Nakap95(gene name synonym)|uniprotkb:Neighbor of A-kinase-anchoring protein 95(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	interpro:IPR034736|interpro:IPR007071("A-kinase anchoring protein 95 (AKAP95)")|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0033127"(regulation of histone phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044839"(cell cycle G2/M phase transition)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:1990904"(ribonucleoprotein complex)|mint:Q9R0L7	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:k4vqjb0Ct+MAwtLNb4HzGRodDtI10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9DBR0	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-4285802|uniprotkb:Q9R0L8|ensembl:ENSMUSP00000002699	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:akap8_mouse(display_long)|uniprotkb:Akap8(gene name)|psi-mi:Akap8(display_short)|uniprotkb:Akap95(gene name synonym)|uniprotkb:A-kinase anchor protein 95 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000024045(gene)|ensembl:ENSMUST00000002699(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015031"(protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0033127"(regulation of histone phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044839"(cell cycle G2/M phase transition)|go:"GO:0045087"(innate immune response)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|interpro:IPR007071("A-kinase anchoring protein 95 (AKAP95)")|interpro:IPR034736|mint:Q9DBR0|refseq:NP_062748.2	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:CboiIO6b/r8YM0jLmJbCdzg5S3U10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q9Z0X1	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-773597|intact:EBI-4282542|uniprotkb:Q1L6K5|ensembl:ENSMUSP00000041104	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:aifm1_mouse(display_long)|uniprotkb:Programmed cell death protein 8(gene name synonym)|uniprotkb:Aifm1(gene name)|psi-mi:Aifm1(display_short)|uniprotkb:Aif(gene name synonym)|uniprotkb:Pdcd8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_001277293.1|refseq:NP_036149.1|ensembl:ENSMUSG00000036932(gene)|ensembl:ENSMUST00000037349(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0004174"(electron-transferring-flavoprotein dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016651"("oxidoreductase activity, acting on NAD(P)H")|go:"GO:0030182"(neuron differentiation)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0071949"(FAD binding)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902510"(regulation of apoptotic DNA fragmentation)|go:"GO:1904045"(cellular response to aldosterone)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR029324|interpro:IPR036188|mint:Q9Z0X1|rcsb pdb:1GV4|rcsb pdb:3GD3|rcsb pdb:3GD4|rcsb pdb:5MIU|rcsb pdb:5MIV	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:c0oYNXW1lpmieqgWc4TZra/RJNk10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:Q8JZQ2	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-3647776|ensembl:ENSMUSP00000025408	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:afg32_mouse(display_long)|uniprotkb:Afg3l2(gene name)|psi-mi:Afg3l2(display_short)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	refseq:NP_081406.1|ensembl:ENSMUSG00000024527(gene)|ensembl:ENSMUST00000025408(transcript)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005745"(m-AAA complex)|go:"GO:0006508"(proteolysis)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016485"(protein processing)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0021675"(nerve development)|go:"GO:0033619"(membrane protein proteolysis)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042407"(cristae formation)|go:"GO:0042552"(myelination)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0055001"(muscle cell development)|go:"GO:0060013"(righting reflex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000642(Peptidase M41)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005936(Peptidase M41, FtsH)|interpro:IPR011546(Peptidase M41, FtsH extracellular)|interpro:IPR027417|interpro:IPR037219|interpro:IPR041569|mint:Q8JZQ2|reactome:R-MMU-8949664	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:MDLdDol9xrpfndcy+9HZ7VW8erI10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q9NRI5	uniprotkb:P60710	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	intact:EBI-353957|ensembl:ENSMUSP00000098066|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q3TI89|uniprotkb:Q3TVP6|uniprotkb:Q64316|uniprotkb:Q6ZWM3	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:actb_mouse(display_long)|uniprotkb:Actb(gene name)|psi-mi:Actb(display_short)|uniprotkb:Beta-actin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612017|imex:IM-28698-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	ensembl:ENSMUSG00000029580(gene)|ensembl:ENSMUST00000100497(transcript)|refseq:NP_031419.1|go:"GO:0002102"(podosome)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60710|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-418990|reactome:R-MMU-437239|reactome:R-MMU-4420097|reactome:R-MMU-445095|reactome:R-MMU-446353|reactome:R-MMU-5250924|reactome:R-MMU-5626467|reactome:R-MMU-5663213|reactome:R-MMU-5663220|reactome:R-MMU-5674135|reactome:R-MMU-5689603|reactome:R-MMU-5696394|reactome:R-MMU-8856828|reactome:R-MMU-9035034|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045121"(membrane raft)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0070160"(tight junction)|go:"GO:0001725"(stress fiber)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|dip:DIP-31574N	-	-	-	figure legend:suppl. table 9 suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc10090	rigid:RtHmka5Hdcbxa9PZ78EQFMpPvUk	false	flag tag:?-?	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q6A065	uniprotkb:Q9NRI5	intact:EBI-2554140|uniprotkb:Q7TQD9|uniprotkb:Q8BJW2|uniprotkb:Q9D3Z0|ensembl:ENSMUSP00000141793	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	psi-mi:ce170_mouse(display_long)|uniprotkb:Kiaa0470(gene name synonym)|uniprotkb:Cep170(gene name)|psi-mi:Cep170(display_short)	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612176|imex:IM-28698-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000057335(gene)|ensembl:ENSMUST00000194727(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0072686"(mitotic spindle)|go:"GO:0120103"(centriolar subdistal appendage)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR026644|interpro:IPR029300|mint:Q6A065|refseq:XP_006497000.1	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	-	-	-	figure legend:suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:gawEp+b6DVpUroRU0JHmHzo7qPg10090	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rigid:2E+dLSroXMwcXqQzRLknxgo+iaA	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Z1B5	uniprotkb:Q9NRI5	intact:EBI-2552918|ensembl:ENSMUSP00000098897|ensembl:ENSMUSP00000112304|uniprotkb:Q9JI53	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	psi-mi:md2l1_mouse(display_long)|uniprotkb:Mad2l1(gene name)|psi-mi:Mad2l1(display_short)|uniprotkb:Mad2a(gene name synonym)|uniprotkb:Mitotic arrest deficient 2-like protein 1(gene name synonym)	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612180|imex:IM-28698-47	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062372.2|reactome:R-MMU-2500257|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-9648025|reactome:R-MMU-2467813|ensembl:ENSMUSG00000029910(gene)|ensembl:ENSMUST00000101343(transcript)|ensembl:ENSMUST00000116605(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR036570|mint:Q9Z1B5|reactome:R-MMU-141405|reactome:R-MMU-141430|reactome:R-MMU-141444|reactome:R-MMU-174184|reactome:R-MMU-176409|reactome:R-MMU-179409|refseq:XP_006506469.1	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	-	-	-	figure legend:suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:T2SuApPGRno6LWCTPwVqAvQEVZQ10090	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rigid:9q+7/9h9nflk2EdeuhpJhkxCYtU	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9CZA6	uniprotkb:Q9NRI5	intact:EBI-309934|uniprotkb:Q3UBS6|uniprotkb:Q3UIC1|uniprotkb:Q9ERR0|ensembl:ENSMUSP00000023359	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	psi-mi:nde1_mouse(display_long)|uniprotkb:Nde1(gene name)|psi-mi:Nde1(display_short)|uniprotkb:Nude(gene name synonym)	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612184|imex:IM-28698-39	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001107557.1|refseq:NP_075806.2|refseq:NP_001272432.1|refseq:NP_001272433.1|refseq:XP_011244302.1|ensembl:ENSMUSG00000022678(gene)|ensembl:ENSMUST00000023359(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030900"(forebrain development)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051642"(centrosome localization)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR006964(NUDE protein, C-terminal)|interpro:IPR033494|mint:Q9CZA6|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9648025|dip:DIP-54638N	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	-	-	-	figure legend:suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:711HNgfdXkDQEAEhRwa4DjKah5s10090	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rigid:eDRtlhC0/TmPtYQb6tlQOQGENVM	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8VD04	uniprotkb:Q9NRI5	intact:EBI-7585099|uniprotkb:A2AEW7|uniprotkb:O35693|uniprotkb:Q69ZP9|uniprotkb:Q3T9C3|intact:MINT-4609304|ensembl:ENSMUSP00000068789	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	psi-mi:grap1_mouse(display_long)|uniprotkb:Gripap1(gene name)|psi-mi:Gripap1(display_short)|uniprotkb:DXImx47e(gene name synonym)|uniprotkb:Kiaa1167(gene name synonym)|uniprotkb:HCMV-interacting protein(gene name synonym)	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612188|imex:IM-28698-49	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_997553.1|ensembl:ENSMUSG00000031153(gene)|ensembl:ENSMUST00000065932(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0098837"(postsynaptic recycling endosome)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098998"(extrinsic component of postsynaptic early endosome membrane)|go:"GO:0099152"(regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0099158"(regulation of recycling endosome localization within postsynapse)|go:"GO:1905244"(regulation of modification of synaptic structure)|interpro:IPR026204|mint:Q8VD04	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	-	comment:mint	-	figure legend:suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:if5RPMbiuuu/rqXtkhbJg8X0Z2w10090	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rigid:3eqmwnDJVN907pLgxUUw4NwWxSE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9ERR1	uniprotkb:Q9NRI5	intact:EBI-646668|uniprotkb:Q9D0Q4|uniprotkb:Q9EPT6|ensembl:ENSMUSP00000018880	intact:EBI-529989|uniprotkb:O75045|uniprotkb:Q5VT44|uniprotkb:Q5VT45|uniprotkb:Q8IXJ0|uniprotkb:Q8IXJ1|uniprotkb:Q9BX19|uniprotkb:Q9NRI3|uniprotkb:Q9NRI4|uniprotkb:C9J6D0|intact:EBI-28977396|ensembl:ENSP00000403888|uniprotkb:A6NLH2|uniprotkb:C4P095|uniprotkb:C4P0A1|uniprotkb:C4P0A3|uniprotkb:C4P0B3|uniprotkb:C4P091|uniprotkb:C4P0B6|uniprotkb:C4P0C1	psi-mi:ndel1_mouse(display_long)|uniprotkb:Protein mNudE-like(gene name synonym)|uniprotkb:Ndel1(gene name)|psi-mi:Ndel1(display_short)|uniprotkb:Nudel(gene name synonym)	psi-mi:disc1_human(display_long)|uniprotkb:DISC1(gene name)|psi-mi:DISC1(display_short)|uniprotkb:KIAA0457(gene name synonym)	psi-mi:"MI:0096"(pull down)	Wilkinson et al. (2019)	imex:IM-28698|pubmed:29961565	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26612192|imex:IM-28698-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076157.2|dip:DIP-29553N|ensembl:ENSMUSG00000018736(gene)|ensembl:ENSMUST00000018880(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000776"(kinetochore)|go:"GO:0001764"(neuron migration)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007100"(mitotic centrosome separation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0016477"(cell migration)|go:"GO:0021799"(cerebral cortex radially oriented cell migration)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030424"(axon)|go:"GO:0031175"(neuron projection development)|go:"GO:0031252"(cell leading edge)|go:"GO:0032418"(lysosome localization)|go:"GO:0033157"(regulation of intracellular protein transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043203"(axon hillock)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051303"(establishment of chromosome localization)|go:"GO:0051642"(centrosome localization)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0060053"(neurofilament cytoskeleton)|go:"GO:0070012"(oligopeptidase activity)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0090724"(central region of growth cone)|go:"GO:1900029"(positive regulation of ruffle assembly)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990138"(neuron projection extension)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR033493|interpro:IPR033494|mint:Q9ERR1|rcsb pdb:5YI4|rcsb pdb:6KZJ|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-5663220|reactome:R-MMU-68877|reactome:R-MMU-9648025|interpro:IPR006964(NUDE protein, C-terminal)	ensembl:ENST00000317586|ensembl:ENSP00000320784|ensembl:ENST00000366633|ensembl:ENSP00000355593|ensembl:ENST00000366636|ensembl:ENSP00000355596|ensembl:ENST00000366637|ensembl:ENSP00000355597|ensembl:ENSP00000403888|ensembl:ENST00000535983|ensembl:ENSP00000443996|ensembl:ENST00000539444|ensembl:ENSP00000440953|ensembl:ENST00000602281|ensembl:ENSP00000473425|ensembl:ENST00000602700|ensembl:ENSP00000473417|ensembl:ENST00000602713|ensembl:ENSP00000473261|ensembl:ENST00000602822|ensembl:ENSP00000473586|ensembl:ENST00000602873|ensembl:ENSP00000473386|ensembl:ENST00000628350|ensembl:ENSP00000487190|ensembl:ENSG00000162946(gene)|ensembl:ENST00000439617(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021852"(pyramidal neuron migration to cerebral cortex)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030286"(dynein complex)|go:"GO:0031929"(TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR026081|mint:Q9NRI5|rcsb pdb:5V4B|refseq:NP_001012975.1|refseq:NP_001012976.1|refseq:NP_001012977.1|refseq:NP_061132.2|refseq:NP_001158011.1|refseq:NP_001158013.1|refseq:NP_001158017.1|refseq:NP_001158018.1|refseq:NP_001158019.1|refseq:NP_001158016.1|refseq:NP_001158027.1|refseq:NP_001158028.1|dip:DIP-33828N	-	-	-	figure legend:suppl fig 4|dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/01/18	2021/02/01	rogid:c69FdVwX1uLP9KZrbrhxKlgGO3c10090	rogid:m8e3Nji5GtYKa5m5lcFJDAUnh/89606	rigid:F54RjC8Np27FwVczX3uVN0lNaZ0	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)