#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9P121	uniprotkb:Q9Y5S1	intact:EBI-4315078|uniprotkb:Q6UXJ3|uniprotkb:A0MTT2|uniprotkb:Q86VJ9|ensembl:ENSP00000363918	intact:EBI-11721896|intact:EBI-28973157|ensembl:ENSP00000342222|uniprotkb:A6NML2|uniprotkb:A8K0Z0|uniprotkb:Q9Y670	psi-mi:ntri_human(display_long)|uniprotkb:NTM(gene name)|psi-mi:NTM(display_short)|uniprotkb:IGLON2(gene name synonym)|uniprotkb:NT(gene name synonym)|uniprotkb:IgLON family member 2(gene name synonym)|uniprotkb:UNQ297/PRO337(orf name)	psi-mi:trpv2_human(display_long)|uniprotkb:TRPV2(gene name)|psi-mi:TRPV2(display_short)|uniprotkb:VRL(gene name synonym)|uniprotkb:Osm-9-like TRP channel 2(gene name synonym)|uniprotkb:Vanilloid receptor-like protein 1(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Doñate-Macián et al. (2018)	imex:IM-28838|pubmed:29719613	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26900505|imex:IM-28838-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001041674.1|refseq:NP_001137530.1|refseq:NP_001137531.1|refseq:NP_057606.1|ensembl:ENSG00000182667(gene)|ensembl:ENST00000374786(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0008038"(neuron recognition)|go:"GO:0031225"(anchored component of membrane)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:6DLF|reactome:R-HSA-163125	ensembl:ENSG00000187688(gene)|ensembl:ENST00000338560(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007600"(sensory perception)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009408"(response to heat)|go:"GO:0009986"(cell surface)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042470"(melanosome)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044297"(cell body)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0070588"(calcium ion transmembrane transport)|ensembl:ENSP00000342222|refseq:NP_057197.2|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR005821(Ion transport)|interpro:IPR008347(Vanilloid receptor)|interpro:IPR020683|interpro:IPR024862|interpro:IPR024865|interpro:IPR036770|rcsb pdb:2F37|reactome:R-HSA-3295583	-	-	-	figure legend:f1b st1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2021/03/31	2021/07/20	rogid:SGoCfe3DYp/3jFAAT7qlTf9yb5s9606	rogid:smxT031fzXTNEj25CzwF+DhPE0o9606	rigid:MUpPfxZIZITcFtxOQOOCRIaFYG8	false	nubg:c-c	cub:n-n	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P05230	uniprotkb:Q9Y5S1	intact:EBI-698068|uniprotkb:P07502|uniprotkb:Q16588|uniprotkb:B2R5T0|uniprotkb:D3DQF2|ensembl:ENSP00000338548|ensembl:ENSP00000352329|ensembl:ENSP00000367285|ensembl:ENSP00000396195|ensembl:ENSP00000404742|ensembl:ENSP00000479024|ensembl:ENSP00000480791|ensembl:ENSP00000480980|ensembl:ENSP00000481868	intact:EBI-11721896|intact:EBI-28973157|ensembl:ENSP00000342222|uniprotkb:A6NML2|uniprotkb:A8K0Z0|uniprotkb:Q9Y670	psi-mi:fgf1_human(display_long)|uniprotkb:Acidic fibroblast growth factor(gene name synonym)|uniprotkb:FGF1(gene name)|psi-mi:FGF1(display_short)|uniprotkb:FGFA(gene name synonym)|uniprotkb:Heparin-binding growth factor 1(gene name synonym)|uniprotkb:Endothelial cell growth factor(gene name synonym)	psi-mi:trpv2_human(display_long)|uniprotkb:TRPV2(gene name)|psi-mi:TRPV2(display_short)|uniprotkb:VRL(gene name synonym)|uniprotkb:Osm-9-like TRP channel 2(gene name synonym)|uniprotkb:Vanilloid receptor-like protein 1(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Doñate-Macián et al. (2018)	imex:IM-28838|pubmed:29719613	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26900545|imex:IM-28838-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000791.1|refseq:NP_001138364.1|refseq:NP_001138406.1|refseq:NP_001138407.1|refseq:NP_149127.1|refseq:NP_001244134.1|refseq:NP_001244136.1|refseq:NP_001244137.1|refseq:NP_001244138.1|refseq:NP_001244139.1|dip:DIP-3787N|ensembl:ENSG00000113578(gene)|ensembl:ENST00000337706(transcript)|ensembl:ENST00000359370(transcript)|ensembl:ENST00000378046(transcript)|ensembl:ENST00000419524(transcript)|ensembl:ENST00000441680(transcript)|ensembl:ENST00000610990(transcript)|ensembl:ENST00000612258(transcript)|ensembl:ENST00000619447(transcript)|ensembl:ENST00000621536(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001525"(angiogenesis)|go:"GO:0001759"(organ induction)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008083"(growth factor activity)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042060"(wound healing)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045542"(positive regulation of cholesterol biosynthetic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0060681"(branch elongation involved in ureteric bud branching)|go:"GO:0072163"(mesonephric epithelium development)|go:"GO:1901509"(regulation of endothelial tube morphogenesis)|go:"GO:1902533"(positive regulation of intracellular signal transduction)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2000544"(regulation of endothelial cell chemotaxis to fibroblast growth factor)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR028210|rcsb pdb:1AXM|rcsb pdb:1DJS|rcsb pdb:1DZC|rcsb pdb:1DZD|rcsb pdb:1E0O|rcsb pdb:1EVT|rcsb pdb:1HKN|rcsb pdb:1JQZ|rcsb pdb:1JT3|rcsb pdb:1JT4|rcsb pdb:1JT5|rcsb pdb:1JT7|rcsb pdb:1JTC|rcsb pdb:1JY0|rcsb pdb:1K5U|rcsb pdb:1K5V|rcsb pdb:1M16|rcsb pdb:1NZK|rcsb pdb:1P63|rcsb pdb:1PZZ|rcsb pdb:1Q03|rcsb pdb:1Q04|rcsb pdb:1QCT|rcsb pdb:1RG8|rcsb pdb:1RML|rcsb pdb:1RY7|rcsb pdb:1YTO|rcsb pdb:1Z2V|rcsb pdb:1Z4S|rcsb pdb:2AFG|rcsb pdb:2AQZ|rcsb pdb:2AXM|rcsb pdb:2ERM|rcsb pdb:2HW9|rcsb pdb:2HWA|rcsb pdb:2HWM|rcsb pdb:2HZ9|rcsb pdb:2K43|rcsb pdb:2K4A|rcsb pdb:2K8R|rcsb pdb:2KI4|rcsb pdb:2KI6|rcsb pdb:2NTD|rcsb pdb:2Q9X|rcsb pdb:2RQ9|rcsb pdb:3B9U|rcsb pdb:3BA4|rcsb pdb:3BA5|rcsb pdb:3BA7|rcsb pdb:3BAD|rcsb pdb:3BAG|rcsb pdb:3BAH|rcsb pdb:3BAO|rcsb pdb:3BAQ|rcsb pdb:3BAU|rcsb pdb:3BAV|rcsb pdb:3BB2|rcsb pdb:3CQA|rcsb pdb:3CRG|rcsb pdb:3CRH|rcsb pdb:3CRI|rcsb pdb:3CU1|rcsb pdb:3FGM|rcsb pdb:3FJ8|rcsb pdb:3FJ9|rcsb pdb:3FJA|rcsb pdb:3FJB|rcsb pdb:3FJC|rcsb pdb:3FJD|rcsb pdb:3FJE|rcsb pdb:3FJF|rcsb pdb:3FJH|rcsb pdb:3FJI|rcsb pdb:3FJJ|rcsb pdb:3FJK|rcsb pdb:3HOM|rcsb pdb:3JUT|rcsb pdb:3K1X|rcsb pdb:3O3Q|rcsb pdb:3OJ2|rcsb pdb:3OJM|rcsb pdb:3OJV|rcsb pdb:3UD7|rcsb pdb:3UD8|rcsb pdb:3UD9|rcsb pdb:3UDA|rcsb pdb:4J23|rcsb pdb:4Q91|rcsb pdb:4Q9G|rcsb pdb:4Q9P|rcsb pdb:4QAL|rcsb pdb:4QBC|rcsb pdb:4QBV|rcsb pdb:4QC4|rcsb pdb:4QO3|rcsb pdb:4XKI|rcsb pdb:4YOL|reactome:R-HSA-109704|reactome:R-HSA-1257604|reactome:R-HSA-1839122|reactome:R-HSA-1839130|reactome:R-HSA-190322|reactome:R-HSA-190370|reactome:R-HSA-190371|reactome:R-HSA-190372|reactome:R-HSA-190373|reactome:R-HSA-190375|reactome:R-HSA-190377|reactome:R-HSA-2033514|reactome:R-HSA-2033519|reactome:R-HSA-2219530|reactome:R-HSA-5654219|reactome:R-HSA-5654221|reactome:R-HSA-5654227|reactome:R-HSA-5654228|reactome:R-HSA-5654687|reactome:R-HSA-5654688|reactome:R-HSA-5654689|reactome:R-HSA-5654693|reactome:R-HSA-5654695|reactome:R-HSA-5654699|reactome:R-HSA-5654700|reactome:R-HSA-5654704|reactome:R-HSA-5654706|reactome:R-HSA-5654710|reactome:R-HSA-5654712|reactome:R-HSA-5654719|reactome:R-HSA-5654720|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655253|reactome:R-HSA-5655302|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-8851708|reactome:R-HSA-8853338	ensembl:ENSG00000187688(gene)|ensembl:ENST00000338560(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007600"(sensory perception)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009408"(response to heat)|go:"GO:0009986"(cell surface)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042470"(melanosome)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044297"(cell body)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0070588"(calcium ion transmembrane transport)|ensembl:ENSP00000342222|refseq:NP_057197.2|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR005821(Ion transport)|interpro:IPR008347(Vanilloid receptor)|interpro:IPR020683|interpro:IPR024862|interpro:IPR024865|interpro:IPR036770|rcsb pdb:2F37|reactome:R-HSA-3295583	-	-	-	figure legend:f1b st1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2021/03/31	2021/07/20	rogid:k1O8U8SRvl73sZ+J+gxmlUjAGow9606	rogid:smxT031fzXTNEj25CzwF+DhPE0o9606	rigid:cFXVM420qkRDB/9B/da7I6UfTII	false	nubg:c-c	cub:n-n	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O60284	uniprotkb:Q9Y5S1	intact:EBI-20890547|ensembl:ENSP00000276480|uniprotkb:Q17RY1	intact:EBI-11721896|intact:EBI-28973157|ensembl:ENSP00000342222|uniprotkb:A6NML2|uniprotkb:A8K0Z0|uniprotkb:Q9Y670	psi-mi:st18_human(display_long)|uniprotkb:Zinc finger protein 387(gene name synonym)|uniprotkb:ST18(gene name)|psi-mi:ST18(display_short)|uniprotkb:KIAA0535(gene name synonym)|uniprotkb:ZNF387(gene name synonym)	psi-mi:trpv2_human(display_long)|uniprotkb:TRPV2(gene name)|psi-mi:TRPV2(display_short)|uniprotkb:VRL(gene name synonym)|uniprotkb:Osm-9-like TRP channel 2(gene name synonym)|uniprotkb:Vanilloid receptor-like protein 1(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Doñate-Macián et al. (2018)	imex:IM-28838|pubmed:29719613	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26900553|imex:IM-28838-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147488(gene)|ensembl:ENST00000276480(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR013681(Myelin transcription factor 1)|interpro:IPR036060|rcsb pdb:2CS8|refseq:NP_055497.1|refseq:XP_006716550.1|refseq:XP_011515931.1|refseq:XP_011515933.1|refseq:XP_011515934.1|refseq:XP_011515935.1|refseq:XP_011515936.1|refseq:XP_011515937.1|refseq:XP_011515938.1|refseq:XP_011515939.1|refseq:XP_011515940.1|refseq:XP_016869536.1|refseq:XP_016869537.1|refseq:XP_016869538.1|refseq:XP_016869539.1|refseq:XP_016869540.1|refseq:XP_016869541.1|refseq:XP_016869542.1|refseq:XP_016869543.1|refseq:XP_016869544.1|refseq:XP_016869545.1|refseq:XP_016869546.1|refseq:XP_016869547.1|refseq:XP_016869548.1|refseq:XP_016869549.1|refseq:XP_016869550.1|refseq:XP_016869551.1|refseq:XP_016869552.1|refseq:XP_016869553.1|refseq:XP_016869554.1|refseq:XP_016869555.1|refseq:XP_016869556.1|refseq:XP_016869557.1|refseq:XP_016869558.1|refseq:XP_016869559.1|refseq:XP_016869560.1	ensembl:ENSG00000187688(gene)|ensembl:ENST00000338560(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007600"(sensory perception)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009408"(response to heat)|go:"GO:0009986"(cell surface)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042470"(melanosome)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044297"(cell body)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0070588"(calcium ion transmembrane transport)|ensembl:ENSP00000342222|refseq:NP_057197.2|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR005821(Ion transport)|interpro:IPR008347(Vanilloid receptor)|interpro:IPR020683|interpro:IPR024862|interpro:IPR024865|interpro:IPR036770|rcsb pdb:2F37|reactome:R-HSA-3295583	-	-	-	figure legend:f1b st1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2021/03/31	2021/07/20	rogid:dBNfQHY9oEkeP7D/b36PBHQFFGQ9606	rogid:smxT031fzXTNEj25CzwF+DhPE0o9606	rigid:4Rwso1016jygwemzUBm0WNeUqew	false	nubg:c-c	cub:c-c	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12979	uniprotkb:Q9Y5S1	intact:EBI-489922|uniprotkb:Q13693|uniprotkb:Q13694|uniprotkb:D3DTH4|uniprotkb:D3DTH3|uniprotkb:B3KW89|uniprotkb:F5H8B3|uniprotkb:B7Z6H7|uniprotkb:F5H3S2|ensembl:ENSP00000303909|ensembl:ENSP00000481740	intact:EBI-11721896|intact:EBI-28973157|ensembl:ENSP00000342222|uniprotkb:A6NML2|uniprotkb:A8K0Z0|uniprotkb:Q9Y670	psi-mi:abr_human(display_long)|uniprotkb:ABR(gene name)|psi-mi:ABR(display_short)	psi-mi:trpv2_human(display_long)|uniprotkb:TRPV2(gene name)|psi-mi:TRPV2(display_short)|uniprotkb:VRL(gene name synonym)|uniprotkb:Osm-9-like TRP channel 2(gene name synonym)|uniprotkb:Vanilloid receptor-like protein 1(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Doñate-Macián et al. (2018)	imex:IM-28838|pubmed:29719613	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26900561|imex:IM-28838-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153218.1|refseq:NP_001083.2|refseq:NP_068781.2|refseq:NP_001243776.1|refseq:NP_001269078.1|refseq:NP_001309769.1|ensembl:ENSG00000159842(gene)|ensembl:ENSG00000278741(gene)|ensembl:ENST00000302538(transcript)|ensembl:ENST00000612118(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030424"(axon)|go:"GO:0043197"(dendritic spine)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000198(RhoGAP)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR035892|interpro:IPR035899|interpro:IPR037769|interpro:IPR037865|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423	ensembl:ENSG00000187688(gene)|ensembl:ENST00000338560(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007600"(sensory perception)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009408"(response to heat)|go:"GO:0009986"(cell surface)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042470"(melanosome)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044297"(cell body)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0070588"(calcium ion transmembrane transport)|ensembl:ENSP00000342222|refseq:NP_057197.2|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR005821(Ion transport)|interpro:IPR008347(Vanilloid receptor)|interpro:IPR020683|interpro:IPR024862|interpro:IPR024865|interpro:IPR036770|rcsb pdb:2F37|reactome:R-HSA-3295583	-	-	-	figure legend:f1b st1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2021/03/31	2021/07/20	rogid:BE2zC9wZOEogjE9LQ3S3D5lIqGs9606	rogid:smxT031fzXTNEj25CzwF+DhPE0o9606	rigid:Modp9aFpZjzdhm6Ox0YQ2j2/WNo	false	nubg:c-c	cub:c-c	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P78508	uniprotkb:Q9Y5S1	intact:EBI-9117877|uniprotkb:A3KME7|uniprotkb:Q5VUT9|uniprotkb:Q8N4I7|uniprotkb:Q92808|ensembl:ENSP00000491250|ensembl:ENSP00000492619|ensembl:ENSP00000495557	intact:EBI-11721896|intact:EBI-28973157|ensembl:ENSP00000342222|uniprotkb:A6NML2|uniprotkb:A8K0Z0|uniprotkb:Q9Y670	psi-mi:kcj10_human(display_long)|uniprotkb:KCNJ10(gene name)|psi-mi:KCNJ10(display_short)|uniprotkb:ATP-dependent inwardly rectifying potassium channel Kir4.1(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir1.2"(gene name synonym)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 10(gene name synonym)	psi-mi:trpv2_human(display_long)|uniprotkb:TRPV2(gene name)|psi-mi:TRPV2(display_short)|uniprotkb:VRL(gene name synonym)|uniprotkb:Osm-9-like TRP channel 2(gene name synonym)|uniprotkb:Vanilloid receptor-like protein 1(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Doñate-Macián et al. (2018)	imex:IM-28838|pubmed:29719613	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26900569|imex:IM-28838-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002232.2|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0044297"(cell body)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0051935"(glutamate reuptake)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0060075"(regulation of resting membrane potential)|go:"GO:0097449"(astrocyte projection)|go:"GO:0097546"(ciliary base)|go:"GO:0098793"(presynapse)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003269(Potassium channel, inwardly rectifying, Kir1.2)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|reactome:R-HSA-1296041|reactome:R-HSA-1296067|reactome:R-HSA-997272|ensembl:ENSG00000177807(gene)|ensembl:ENST00000638728(transcript)|ensembl:ENST00000638868(transcript)|ensembl:ENST00000644903(transcript)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0007601"(visual perception)|go:"GO:0007628"(adult walking behavior)|go:"GO:0015272"(ATP-activated inward rectifier potassium channel activity)	ensembl:ENSG00000187688(gene)|ensembl:ENST00000338560(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007600"(sensory perception)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009408"(response to heat)|go:"GO:0009986"(cell surface)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042470"(melanosome)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044297"(cell body)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0070588"(calcium ion transmembrane transport)|ensembl:ENSP00000342222|refseq:NP_057197.2|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR005821(Ion transport)|interpro:IPR008347(Vanilloid receptor)|interpro:IPR020683|interpro:IPR024862|interpro:IPR024865|interpro:IPR036770|rcsb pdb:2F37|reactome:R-HSA-3295583	-	-	-	figure legend:f1b st1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2021/03/31	2021/07/20	rogid:4RhA3NWgH7eTMHQt0ovdxr/S5849606	rogid:smxT031fzXTNEj25CzwF+DhPE0o9606	rigid:+OL4x0C9KVAEkpiOp9uLTG3g5hY	false	nubg:c-c	cub:c-c	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P30086	uniprotkb:Q9Y5S1	intact:EBI-716384|uniprotkb:B2R4S1|ensembl:ENSP00000261313	intact:EBI-11721896|intact:EBI-28973157|ensembl:ENSP00000342222|uniprotkb:A6NML2|uniprotkb:A8K0Z0|uniprotkb:Q9Y670	psi-mi:pebp1_human(display_long)|uniprotkb:Prostatic-binding protein(gene name synonym)|uniprotkb:HCNPpp(gene name synonym)|uniprotkb:Neuropolypeptide h3(gene name synonym)|uniprotkb:Raf kinase inhibitor protein(gene name synonym)|uniprotkb:PEBP1(gene name)|psi-mi:PEBP1(display_short)|uniprotkb:PEBP(gene name synonym)|uniprotkb:PBP(gene name synonym)	psi-mi:trpv2_human(display_long)|uniprotkb:TRPV2(gene name)|psi-mi:TRPV2(display_short)|uniprotkb:VRL(gene name synonym)|uniprotkb:Osm-9-like TRP channel 2(gene name synonym)|uniprotkb:Vanilloid receptor-like protein 1(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Doñate-Macián et al. (2018)	imex:IM-28838|pubmed:29719613	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26900577|imex:IM-28838-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002558.1|ensembl:ENSG00000089220(gene)|ensembl:ENST00000261313(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001858(Phosphatidylethanolamine-binding, conserved site)|interpro:IPR008914(Phosphatidylethanolamine-binding protein PEBP)|interpro:IPR035810|interpro:IPR036610|mint:P30086|rcsb pdb:1BD9|rcsb pdb:1BEH|rcsb pdb:2L7W|rcsb pdb:2QYQ|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|dip:DIP-44269N	ensembl:ENSG00000187688(gene)|ensembl:ENST00000338560(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007600"(sensory perception)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009408"(response to heat)|go:"GO:0009986"(cell surface)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042470"(melanosome)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044297"(cell body)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0070588"(calcium ion transmembrane transport)|ensembl:ENSP00000342222|refseq:NP_057197.2|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR005821(Ion transport)|interpro:IPR008347(Vanilloid receptor)|interpro:IPR020683|interpro:IPR024862|interpro:IPR024865|interpro:IPR036770|rcsb pdb:2F37|reactome:R-HSA-3295583	-	-	-	figure legend:f1b st1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2021/03/31	2021/07/20	rogid:6NY/YmyO5c8tNYfXtujwvP2chIc9606	rogid:smxT031fzXTNEj25CzwF+DhPE0o9606	rigid:pdgjxv+A+yG5/UpwhDsSdu+6rJQ	false	nubg:c-c	cub:c-c	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8IWA5	uniprotkb:Q9Y5S1	intact:EBI-11722896|uniprotkb:B2RBB1|uniprotkb:B3KNH3|uniprotkb:B4DFJ0|uniprotkb:F2Q9D7|uniprotkb:Q658V1|uniprotkb:Q658Z2|uniprotkb:Q6PJV7|uniprotkb:Q8N2F0|uniprotkb:Q9NY68|ensembl:ENSP00000336888	intact:EBI-11721896|intact:EBI-28973157|ensembl:ENSP00000342222|uniprotkb:A6NML2|uniprotkb:A8K0Z0|uniprotkb:Q9Y670	psi-mi:ctl2_human(display_long)|uniprotkb:SLC44A2(gene name)|psi-mi:SLC44A2(display_short)|uniprotkb:CTL2(gene name synonym)|uniprotkb:Solute carrier family 44 member 2(gene name synonym)|uniprotkb:PSEC0210(orf name)	psi-mi:trpv2_human(display_long)|uniprotkb:TRPV2(gene name)|psi-mi:TRPV2(display_short)|uniprotkb:VRL(gene name synonym)|uniprotkb:Osm-9-like TRP channel 2(gene name synonym)|uniprotkb:Vanilloid receptor-like protein 1(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Doñate-Macián et al. (2018)	imex:IM-28838|pubmed:29719613	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26900589|imex:IM-28838-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001138528.1|refseq:NP_065161.3|refseq:XP_005260054.1|ensembl:ENSG00000129353(gene)|ensembl:ENST00000335757(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0035579"(specific granule membrane)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0055085"(transmembrane transport)|go:"GO:0070062"(extracellular exosome)|interpro:IPR007603(Protein of unknown function DUF580)|mint:Q8IWA5|reactome:R-HSA-1483191|reactome:R-HSA-425366|reactome:R-HSA-6798695	ensembl:ENSG00000187688(gene)|ensembl:ENST00000338560(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007600"(sensory perception)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009408"(response to heat)|go:"GO:0009986"(cell surface)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042470"(melanosome)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044297"(cell body)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0070588"(calcium ion transmembrane transport)|ensembl:ENSP00000342222|refseq:NP_057197.2|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR005821(Ion transport)|interpro:IPR008347(Vanilloid receptor)|interpro:IPR020683|interpro:IPR024862|interpro:IPR024865|interpro:IPR036770|rcsb pdb:2F37|reactome:R-HSA-3295583	-	-	-	figure legend:f1b st1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2021/03/31	2021/07/20	rogid:SSl8Mo7YUgoqMyEdqv9w02Qj0iM9606	rogid:smxT031fzXTNEj25CzwF+DhPE0o9606	rigid:QUkjdjDhKAdTSJg+GKSnX4vF0HE	false	nubg:c-c	cub:c-c	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96PE5	uniprotkb:Q9Y5S1	intact:EBI-21392143|ensembl:ENSP00000360214|uniprotkb:A8MX69|uniprotkb:A8MYG4|uniprotkb:B4DK96|uniprotkb:B4DKH0|uniprotkb:Q5W102	intact:EBI-11721896|intact:EBI-28973157|ensembl:ENSP00000342222|uniprotkb:A6NML2|uniprotkb:A8K0Z0|uniprotkb:Q9Y670	psi-mi:opali_human(display_long)|uniprotkb:OPALIN(gene name)|psi-mi:OPALIN(display_short)|uniprotkb:HTMP10(gene name synonym)|uniprotkb:TMEM10(gene name synonym)|uniprotkb:Oligodendrocytic myelin paranodal and inner loop protein(gene name synonym)|uniprotkb:Transmembrane protein 10(gene name synonym)	psi-mi:trpv2_human(display_long)|uniprotkb:TRPV2(gene name)|psi-mi:TRPV2(display_short)|uniprotkb:VRL(gene name synonym)|uniprotkb:Osm-9-like TRP channel 2(gene name synonym)|uniprotkb:Vanilloid receptor-like protein 1(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Doñate-Macián et al. (2018)	imex:IM-28838|pubmed:29719613	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26900597|imex:IM-28838-41	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000197430(gene)|ensembl:ENST00000371172(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0048713"(regulation of oligodendrocyte differentiation)|interpro:IPR026609|refseq:NP_001035191.1|refseq:NP_001035192.1|refseq:NP_001271249.1|refseq:NP_001271250.1|refseq:NP_001271251.1|refseq:NP_001271252.1|refseq:NP_001271253.1|refseq:NP_001271255.1|refseq:NP_001271256.1|refseq:NP_149984.1	ensembl:ENSG00000187688(gene)|ensembl:ENST00000338560(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007600"(sensory perception)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009408"(response to heat)|go:"GO:0009986"(cell surface)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042470"(melanosome)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044297"(cell body)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0070588"(calcium ion transmembrane transport)|ensembl:ENSP00000342222|refseq:NP_057197.2|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR005821(Ion transport)|interpro:IPR008347(Vanilloid receptor)|interpro:IPR020683|interpro:IPR024862|interpro:IPR024865|interpro:IPR036770|rcsb pdb:2F37|reactome:R-HSA-3295583	-	-	-	figure legend:f1b st1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2021/03/31	2021/07/20	rogid:wGoWtiptqLpFF+rlq7dVY86JwFc9606	rogid:smxT031fzXTNEj25CzwF+DhPE0o9606	rigid:lUuKUojRTeWKFhdReh/X82Oz8zY	false	nubg:c-c	cub:c-c	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P55285	uniprotkb:Q9Y5S1	intact:EBI-26900605|intact:EBI-28987066|ensembl:ENSP00000265071|uniprotkb:A8K5H5|uniprotkb:Q9BWS0	intact:EBI-11721896|intact:EBI-28973157|ensembl:ENSP00000342222|uniprotkb:A6NML2|uniprotkb:A8K0Z0|uniprotkb:Q9Y670	psi-mi:cadh6_human(display_long)|uniprotkb:CDH6(gene name)|psi-mi:CDH6(display_short)|uniprotkb:Kidney cadherin(gene name synonym)	psi-mi:trpv2_human(display_long)|uniprotkb:TRPV2(gene name)|psi-mi:TRPV2(display_short)|uniprotkb:VRL(gene name synonym)|uniprotkb:Osm-9-like TRP channel 2(gene name synonym)|uniprotkb:Vanilloid receptor-like protein 1(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Doñate-Macián et al. (2018)	imex:IM-28838|pubmed:29719613	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26900642|imex:IM-28838-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000265071|ensembl:ENSG00000113361(gene)|ensembl:ENST00000265071(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016342"(catenin complex)|go:"GO:0030054"(cell junction)|go:"GO:0034332"(adherens junction organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR039808|rcsb pdb:5VEB|reactome:R-HSA-418990|refseq:NP_004923.1|refseq:XP_011512223.1|refseq:XP_016864399.1|refseq:XP_016864400.1	ensembl:ENSG00000187688(gene)|ensembl:ENST00000338560(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007600"(sensory perception)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009408"(response to heat)|go:"GO:0009986"(cell surface)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042470"(melanosome)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044297"(cell body)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0070588"(calcium ion transmembrane transport)|ensembl:ENSP00000342222|refseq:NP_057197.2|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR005821(Ion transport)|interpro:IPR008347(Vanilloid receptor)|interpro:IPR020683|interpro:IPR024862|interpro:IPR024865|interpro:IPR036770|rcsb pdb:2F37|reactome:R-HSA-3295583	-	-	-	figure legend:f1b st1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2021/03/31	2021/07/20	rogid:WJPMbJQH85mqQEjcMs6wOWRbZaM9606	rogid:smxT031fzXTNEj25CzwF+DhPE0o9606	rigid:NkQFt0hcV2/g45b5gy6+SDBADQU	false	nubg:c-c	cub:c-c	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9Y2H2	uniprotkb:Q9Y5S1	intact:EBI-8798212|ensembl:ENSP00000497527|uniprotkb:Q9H3D9|uniprotkb:Q2T9J4|uniprotkb:Q9NT51|uniprotkb:Q6NVY2|uniprotkb:D3DRD1|uniprotkb:Q86U97|uniprotkb:Q5W135|uniprotkb:Q5W136|uniprotkb:B3KRF1	intact:EBI-11721896|intact:EBI-28973157|ensembl:ENSP00000342222|uniprotkb:A6NML2|uniprotkb:A8K0Z0|uniprotkb:Q9Y670	psi-mi:sac2_human(display_long)|uniprotkb:Inositol polyphosphate 5-phosphatase F(gene name synonym)|uniprotkb:KIAA0966(gene name synonym)|uniprotkb:SAC2(gene name synonym)|uniprotkb:Sac domain-containing inositol phosphatase 2(gene name synonym)|uniprotkb:INPP5F(gene name)|psi-mi:INPP5F(display_short)|uniprotkb:Sac domain-containing phosphoinositide 4-phosphatase 2(gene name synonym)|uniprotkb:MSTP007(orf name)|uniprotkb:MSTP047(orf name)	psi-mi:trpv2_human(display_long)|uniprotkb:TRPV2(gene name)|psi-mi:TRPV2(display_short)|uniprotkb:VRL(gene name synonym)|uniprotkb:Osm-9-like TRP channel 2(gene name synonym)|uniprotkb:Vanilloid receptor-like protein 1(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Doñate-Macián et al. (2018)	imex:IM-28838|pubmed:29719613	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26900651|imex:IM-28838-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000198825(gene)|ensembl:ENST00000650623(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005769"(early endosome)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008934"(inositol monophosphate 1-phosphatase activity)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031161"(phosphatidylinositol catabolic process)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034595"(phosphatidylinositol phosphate 5-phosphatase activity)|go:"GO:0034596"(phosphatidylinositol phosphate 4-phosphatase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043812"(phosphatidylinositol-4-phosphate phosphatase activity)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0052832"(inositol monophosphate 3-phosphatase activity)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0055037"(recycling endosome)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:2000145"(regulation of cell motility)|go:"GO:2001135"(regulation of endocytic recycling)|interpro:IPR002013(Synaptojanin, N-terminal)|interpro:IPR022158|interpro:IPR034753|rcsb pdb:4XUU|reactome:R-HSA-1660516|go:"GO:0052833"(inositol monophosphate 4-phosphatase activity)|refseq:NP_001230123.1|refseq:NP_001230124.1|refseq:NP_055752.1	ensembl:ENSG00000187688(gene)|ensembl:ENST00000338560(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007600"(sensory perception)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009408"(response to heat)|go:"GO:0009986"(cell surface)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042470"(melanosome)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044297"(cell body)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0070588"(calcium ion transmembrane transport)|ensembl:ENSP00000342222|refseq:NP_057197.2|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR005821(Ion transport)|interpro:IPR008347(Vanilloid receptor)|interpro:IPR020683|interpro:IPR024862|interpro:IPR024865|interpro:IPR036770|rcsb pdb:2F37|reactome:R-HSA-3295583	-	-	-	figure legend:f1b st1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2021/03/31	2021/07/20	rogid:b12Qs0ZRPD65du+ryoa+PfLkqw89606	rogid:smxT031fzXTNEj25CzwF+DhPE0o9606	rigid:xa9kGdHIZTt4FfTYRiI001c1QdA	false	nubg:c-c	cub:c-c	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P78356	uniprotkb:Q9Y5S1	intact:EBI-947090|uniprotkb:Q5U0E8|uniprotkb:Q8TBP2|ensembl:ENSP00000480776|ensembl:ENSP00000482548	intact:EBI-11721896|intact:EBI-28973157|ensembl:ENSP00000342222|uniprotkb:A6NML2|uniprotkb:A8K0Z0|uniprotkb:Q9Y670	psi-mi:pi42b_human(display_long)|uniprotkb:PIP4K2B(gene name)|psi-mi:PIP4K2B(display_short)|uniprotkb:"PtdIns(5)P-4-kinase isoform 2-beta"(gene name synonym)|uniprotkb:Diphosphoinositide kinase 2-beta(gene name synonym)|uniprotkb:PIP5K2B(gene name synonym)|uniprotkb:1-phosphatidylinositol 5-phosphate 4-kinase 2-beta(gene name synonym)|uniprotkb:Phosphatidylinositol 5-phosphate 4-kinase type II beta(gene name synonym)	psi-mi:trpv2_human(display_long)|uniprotkb:TRPV2(gene name)|psi-mi:TRPV2(display_short)|uniprotkb:VRL(gene name synonym)|uniprotkb:Osm-9-like TRP channel 2(gene name synonym)|uniprotkb:Vanilloid receptor-like protein 1(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Doñate-Macián et al. (2018)	imex:IM-28838|pubmed:29719613	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26900672|imex:IM-28838-43	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003550.1|ensembl:ENSG00000276293(gene)|ensembl:ENSG00000277292(gene)|ensembl:ENST00000613180(transcript)|ensembl:ENST00000619039(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016308"(1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:0016309"(1-phosphatidylinositol-5-phosphate 4-kinase activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0061909"(autophagosome-lysosome fusion)|go:"GO:0090217"(negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:1902635"(1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027484|mint:P78356|rcsb pdb:1BO1|rcsb pdb:3WZZ|rcsb pdb:3X01|rcsb pdb:3X02|rcsb pdb:3X03|rcsb pdb:3X04|rcsb pdb:3X05|rcsb pdb:3X06|rcsb pdb:3X07|rcsb pdb:3X08|rcsb pdb:3X09|rcsb pdb:3X0A|rcsb pdb:3X0B|rcsb pdb:3X0C|rcsb pdb:6K4G|rcsb pdb:6K4H|rcsb pdb:7N80|rcsb pdb:7N81|reactome:R-HSA-1660499|reactome:R-HSA-6811555|reactome:R-HSA-6811558|reactome:R-HSA-8847453	ensembl:ENSG00000187688(gene)|ensembl:ENST00000338560(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007600"(sensory perception)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009408"(response to heat)|go:"GO:0009986"(cell surface)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042470"(melanosome)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044297"(cell body)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0070588"(calcium ion transmembrane transport)|ensembl:ENSP00000342222|refseq:NP_057197.2|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR005821(Ion transport)|interpro:IPR008347(Vanilloid receptor)|interpro:IPR020683|interpro:IPR024862|interpro:IPR024865|interpro:IPR036770|rcsb pdb:2F37|reactome:R-HSA-3295583	-	-	-	figure legend:f1b st1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2021/03/31	2021/07/20	rogid:sKU3t4ChBZODcGl1ZUqfncyNkSo9606	rogid:smxT031fzXTNEj25CzwF+DhPE0o9606	rigid:OOmM5iycKmooqTvr4Kf4ltV5cNs	false	nubg:c-c	cub:c-c	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P84077	uniprotkb:Q9Y5S1	intact:EBI-447171|uniprotkb:P10947|uniprotkb:P32889|ensembl:ENSP00000272102|ensembl:ENSP00000440005|ensembl:ENSP00000442980	intact:EBI-11721896|intact:EBI-28973157|ensembl:ENSP00000342222|uniprotkb:A6NML2|uniprotkb:A8K0Z0|uniprotkb:Q9Y670	psi-mi:arf1_human(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)	psi-mi:trpv2_human(display_long)|uniprotkb:TRPV2(gene name)|psi-mi:TRPV2(display_short)|uniprotkb:VRL(gene name synonym)|uniprotkb:Osm-9-like TRP channel 2(gene name synonym)|uniprotkb:Vanilloid receptor-like protein 1(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Doñate-Macián et al. (2018)	imex:IM-28838|pubmed:29719613	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26900680|imex:IM-28838-45	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001019397.1|refseq:NP_001019398.1|refseq:NP_001019399.1|refseq:NP_001649.1|dip:DIP-31597N|ensembl:ENSG00000143761(gene)|ensembl:ENST00000272102(transcript)|ensembl:ENST00000540651(transcript)|ensembl:ENST00000541182(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007015"(actin filament organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0043005"(neuron projection)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0055108"(Golgi to transport vesicle transport)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070142"(synaptic vesicle budding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097212"(lysosomal membrane organization)|go:"GO:0098586"(cellular response to virus)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902307"(positive regulation of sodium ion transmembrane transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:1903725"(regulation of phospholipid metabolic process)|go:"GO:1990386"(mitotic cleavage furrow ingression)|go:"GO:1990583"(phospholipase D activator activity)|interpro:IPR005225(Small GTP-binding protein)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P84077|rcsb pdb:1HUR|rcsb pdb:1RE0|rcsb pdb:1U81|rcsb pdb:3O47|rcsb pdb:4HMY|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|rcsb pdb:6DFF|rcsb pdb:6FAE|rcsb pdb:7MGE|reactome:R-HSA-1660499|reactome:R-HSA-1660514|reactome:R-HSA-167590|reactome:R-HSA-199992|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-8950505	ensembl:ENSG00000187688(gene)|ensembl:ENST00000338560(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007600"(sensory perception)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009408"(response to heat)|go:"GO:0009986"(cell surface)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042470"(melanosome)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044297"(cell body)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0070588"(calcium ion transmembrane transport)|ensembl:ENSP00000342222|refseq:NP_057197.2|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR005821(Ion transport)|interpro:IPR008347(Vanilloid receptor)|interpro:IPR020683|interpro:IPR024862|interpro:IPR024865|interpro:IPR036770|rcsb pdb:2F37|reactome:R-HSA-3295583	-	-	-	figure legend:f1b st1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2021/03/31	2021/07/20	rogid:zray9asm6VonxpuJpv0dRBspPt89606	rogid:smxT031fzXTNEj25CzwF+DhPE0o9606	rigid:CSd9yw1L1vHXxJUpzmOWqskQvz0	false	nubg:c-c	cub:c-c	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P60201	uniprotkb:Q9Y5S1	intact:EBI-8653150|uniprotkb:P06905|uniprotkb:P04400|intact:MINT-8164000|uniprotkb:Q502Y1|uniprotkb:Q6FHZ6|ensembl:ENSP00000481006|ensembl:ENSP00000484450	intact:EBI-11721896|intact:EBI-28973157|ensembl:ENSP00000342222|uniprotkb:A6NML2|uniprotkb:A8K0Z0|uniprotkb:Q9Y670	psi-mi:mypr_human(display_long)|uniprotkb:PLP1(gene name)|psi-mi:PLP1(display_short)|uniprotkb:Lipophilin(gene name synonym)|uniprotkb:PLP(gene name synonym)	psi-mi:trpv2_human(display_long)|uniprotkb:TRPV2(gene name)|psi-mi:TRPV2(display_short)|uniprotkb:VRL(gene name synonym)|uniprotkb:Osm-9-like TRP channel 2(gene name synonym)|uniprotkb:Vanilloid receptor-like protein 1(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Doñate-Macián et al. (2018)	imex:IM-28838|pubmed:29719613	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26900688|imex:IM-28838-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001291933.1|refseq:NP_955772.1|refseq:NP_000524.3|refseq:NP_001122306.1|ensembl:ENSG00000123560(gene)|ensembl:ENST00000612423(transcript)|ensembl:ENST00000621218(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008366"(axon ensheathment)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014002"(astrocyte development)|go:"GO:0019911"(structural constituent of myelin sheath)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031175"(neuron projection development)|go:"GO:0034683"(integrin alphav-beta3 complex)|go:"GO:0042759"(long-chain fatty acid biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0061564"(axon development)|go:"GO:0098990"(AMPA selective glutamate receptor signaling pathway)|go:"GO:1904427"(positive regulation of calcium ion transmembrane transport)|interpro:IPR001614(Myelin proteolipid protein PLP)|interpro:IPR018237|mint:P60201|rcsb pdb:2XPG	ensembl:ENSG00000187688(gene)|ensembl:ENST00000338560(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007600"(sensory perception)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009408"(response to heat)|go:"GO:0009986"(cell surface)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042470"(melanosome)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044297"(cell body)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0070588"(calcium ion transmembrane transport)|ensembl:ENSP00000342222|refseq:NP_057197.2|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR005821(Ion transport)|interpro:IPR008347(Vanilloid receptor)|interpro:IPR020683|interpro:IPR024862|interpro:IPR024865|interpro:IPR036770|rcsb pdb:2F37|reactome:R-HSA-3295583	-	comment:mint	-	figure legend:f1b st1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2021/03/31	2021/07/20	rogid:b7pt7FJVt10Iu1tTMeiVYEu5r/k9606	rogid:smxT031fzXTNEj25CzwF+DhPE0o9606	rigid:RbQgIBjFghzjt/xzcPCbMN18Wrs	false	nubg:c-c	cub:c-c	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75056	uniprotkb:Q9Y5S1	intact:EBI-1642090|uniprotkb:Q5T1Z6|uniprotkb:Q5T1Z7|uniprotkb:Q96CT3|uniprotkb:Q96PR8|ensembl:ENSP00000344468	intact:EBI-11721896|intact:EBI-28973157|ensembl:ENSP00000342222|uniprotkb:A6NML2|uniprotkb:A8K0Z0|uniprotkb:Q9Y670	psi-mi:sdc3_human(display_long)|uniprotkb:SDC3(gene name)|psi-mi:SDC3(display_short)|uniprotkb:KIAA0468(gene name synonym)	psi-mi:trpv2_human(display_long)|uniprotkb:TRPV2(gene name)|psi-mi:TRPV2(display_short)|uniprotkb:VRL(gene name synonym)|uniprotkb:Osm-9-like TRP channel 2(gene name synonym)|uniprotkb:Vanilloid receptor-like protein 1(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Doñate-Macián et al. (2018)	imex:IM-28838|pubmed:29719613	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26900696|imex:IM-28838-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055469.3|dip:DIP-29944N|ensembl:ENSG00000162512(gene)|ensembl:ENST00000339394(transcript)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0044393"(microspike)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001050(Syndecan)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR027789|interpro:IPR030479|interpro:IPR031194|reactome:R-HSA-1971475|reactome:R-HSA-2022928|reactome:R-HSA-2024096|reactome:R-HSA-202733|reactome:R-HSA-3000170|reactome:R-HSA-3560783|reactome:R-HSA-3560801|reactome:R-HSA-3656237|reactome:R-HSA-3656253|reactome:R-HSA-4420332|reactome:R-HSA-975634	ensembl:ENSG00000187688(gene)|ensembl:ENST00000338560(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007600"(sensory perception)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009408"(response to heat)|go:"GO:0009986"(cell surface)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042470"(melanosome)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044297"(cell body)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0070588"(calcium ion transmembrane transport)|ensembl:ENSP00000342222|refseq:NP_057197.2|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR005821(Ion transport)|interpro:IPR008347(Vanilloid receptor)|interpro:IPR020683|interpro:IPR024862|interpro:IPR024865|interpro:IPR036770|rcsb pdb:2F37|reactome:R-HSA-3295583	-	-	-	figure legend:f1b st1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2021/03/31	2021/07/20	rogid:6wbbzXVuCZFtidcnoAjAW5x5UAU9606	rogid:smxT031fzXTNEj25CzwF+DhPE0o9606	rigid:fBCduugrUqHltOLhlGMhln0XHVw	false	nubg:c-c	cub:c-c	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O60359	uniprotkb:Q9Y5S1	intact:EBI-17773645|ensembl:ENSP00000005284	intact:EBI-11721896|intact:EBI-28973157|ensembl:ENSP00000342222|uniprotkb:A6NML2|uniprotkb:A8K0Z0|uniprotkb:Q9Y670	psi-mi:ccg3_human(display_long)|uniprotkb:Neuronal voltage-gated calcium channel gamma-3 subunit(gene name synonym)|uniprotkb:Transmembrane AMPAR regulatory protein gamma-3(gene name synonym)|uniprotkb:CACNG3(gene name)|psi-mi:CACNG3(display_short)	psi-mi:trpv2_human(display_long)|uniprotkb:TRPV2(gene name)|psi-mi:TRPV2(display_short)|uniprotkb:VRL(gene name synonym)|uniprotkb:Osm-9-like TRP channel 2(gene name synonym)|uniprotkb:Vanilloid receptor-like protein 1(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Doñate-Macián et al. (2018)	imex:IM-28838|pubmed:29719613	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26900704|imex:IM-28838-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006530.1|go:"GO:0060076"(excitatory synapse)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098943"(neurotransmitter receptor transport, postsynaptic endosome to lysosome)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099590"(neurotransmitter receptor internalization)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000969"(positive regulation of AMPA receptor activity)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR008368(Voltage-dependent calcium channel, gamma subunit)|reactome:R-HSA-399719|reactome:R-HSA-5682910|ensembl:ENSG00000006116(gene)|ensembl:ENST00000005284(transcript)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006605"(protein targeting)|go:"GO:0006816"(calcium ion transport)|go:"GO:0008104"(protein localization)|go:"GO:0016247"(channel regulator activity)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0036477"(somatodendritic compartment)	ensembl:ENSG00000187688(gene)|ensembl:ENST00000338560(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007600"(sensory perception)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009408"(response to heat)|go:"GO:0009986"(cell surface)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042470"(melanosome)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044297"(cell body)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0070588"(calcium ion transmembrane transport)|ensembl:ENSP00000342222|refseq:NP_057197.2|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR005821(Ion transport)|interpro:IPR008347(Vanilloid receptor)|interpro:IPR020683|interpro:IPR024862|interpro:IPR024865|interpro:IPR036770|rcsb pdb:2F37|reactome:R-HSA-3295583	-	-	-	figure legend:f1b st1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2021/03/31	2021/07/20	rogid:xBcrEODFcqZgszQlcr8c9B36aqQ9606	rogid:smxT031fzXTNEj25CzwF+DhPE0o9606	rigid:dSG7khB/hKyYsVsGmfHHfUY4o5E	false	nubg:c-c	cub:c-c	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6UXB8	uniprotkb:Q9Y5S1	intact:EBI-12810028|ensembl:ENSP00000362778|ensembl:ENSP00000478888|ensembl:ENSP00000497550|uniprotkb:Q6ZVG9|uniprotkb:Q8IYL8|uniprotkb:Q8NBK0|uniprotkb:Q8TCB8	intact:EBI-11721896|intact:EBI-28973157|ensembl:ENSP00000342222|uniprotkb:A6NML2|uniprotkb:A8K0Z0|uniprotkb:Q9Y670	psi-mi:pi16_human(display_long)|uniprotkb:PI16(gene name)|psi-mi:PI16(display_short)|uniprotkb:CRISP9(gene name synonym)|uniprotkb:Cysteine-rich secretory protein 9(gene name synonym)|uniprotkb:PSP94-binding protein(gene name synonym)|uniprotkb:PSPBP(gene name synonym)|uniprotkb:PSEC0164(orf name)|uniprotkb:UNQ289/PRO328(orf name)	psi-mi:trpv2_human(display_long)|uniprotkb:TRPV2(gene name)|psi-mi:TRPV2(display_short)|uniprotkb:VRL(gene name synonym)|uniprotkb:Osm-9-like TRP channel 2(gene name synonym)|uniprotkb:Vanilloid receptor-like protein 1(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Doñate-Macián et al. (2018)	imex:IM-28838|pubmed:29719613	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26900712|imex:IM-28838-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000164530(gene)|ensembl:ENST00000373674(transcript)|ensembl:ENST00000611814(transcript)|ensembl:ENST00000647861(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0030414"(peptidase inhibitor activity)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|interpro:IPR001283(Allergen V5/Tpx-1 related)|interpro:IPR014044(SCP-like extracellular)|interpro:IPR018244|interpro:IPR035940|refseq:NP_001186088.1|refseq:NP_699201.2|refseq:XP_005248974.1|refseq:XP_011512677.1|refseq:XP_016865919.1	ensembl:ENSG00000187688(gene)|ensembl:ENST00000338560(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007600"(sensory perception)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009408"(response to heat)|go:"GO:0009986"(cell surface)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042470"(melanosome)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044297"(cell body)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0070588"(calcium ion transmembrane transport)|ensembl:ENSP00000342222|refseq:NP_057197.2|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR005821(Ion transport)|interpro:IPR008347(Vanilloid receptor)|interpro:IPR020683|interpro:IPR024862|interpro:IPR024865|interpro:IPR036770|rcsb pdb:2F37|reactome:R-HSA-3295583	-	-	-	figure legend:f1b st1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2021/03/31	2021/07/20	rogid:Om0+EFE08EwAi6HdKGzK5WBl5eM9606	rogid:smxT031fzXTNEj25CzwF+DhPE0o9606	rigid:D0zEp9wvRlN5Mx9cdFlt5TRLke0	false	nubg:c-c	cub:c-c	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NTJ5	uniprotkb:Q9Y5S1	intact:EBI-3917235|uniprotkb:B4DK71|uniprotkb:Q7LA14|uniprotkb:A8K527|uniprotkb:Q96AX7|uniprotkb:Q9NQ46|uniprotkb:Q9NQ57|uniprotkb:O94935|uniprotkb:Q7LA22|ensembl:ENSP00000373713|ensembl:ENSP00000500361	intact:EBI-11721896|intact:EBI-28973157|ensembl:ENSP00000342222|uniprotkb:A6NML2|uniprotkb:A8K0Z0|uniprotkb:Q9Y670	psi-mi:sac1_human(display_long)|uniprotkb:SACM1L(gene name)|psi-mi:SACM1L(display_short)|uniprotkb:KIAA0851(gene name synonym)|uniprotkb:Suppressor of actin mutations 1-like protein(gene name synonym)|uniprotkb:Phosphatidylinositol-4-phosphate phosphatase(gene name synonym)|uniprotkb:SAC1(gene name synonym)	psi-mi:trpv2_human(display_long)|uniprotkb:TRPV2(gene name)|psi-mi:TRPV2(display_short)|uniprotkb:VRL(gene name synonym)|uniprotkb:Osm-9-like TRP channel 2(gene name synonym)|uniprotkb:Vanilloid receptor-like protein 1(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Doñate-Macián et al. (2018)	imex:IM-28838|pubmed:29719613	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26900720|imex:IM-28838-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011531802.1|refseq:NP_054735.3|refseq:NP_001306001.1|refseq:NP_001306002.1|ensembl:ENSG00000211456(gene)|ensembl:ENST00000389061(transcript)|ensembl:ENST00000672477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034593"(phosphatidylinositol bisphosphate phosphatase activity)|go:"GO:0034596"(phosphatidylinositol phosphate 4-phosphatase activity)|go:"GO:0043812"(phosphatidylinositol-4-phosphate phosphatase activity)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0140268"(endoplasmic reticulum-plasma membrane contact site)|interpro:IPR002013(Synaptojanin, N-terminal)|reactome:R-HSA-1483248|reactome:R-HSA-1660514|go:"GO:0016791"(phosphatase activity)	ensembl:ENSG00000187688(gene)|ensembl:ENST00000338560(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007600"(sensory perception)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009408"(response to heat)|go:"GO:0009986"(cell surface)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042470"(melanosome)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044297"(cell body)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0070588"(calcium ion transmembrane transport)|ensembl:ENSP00000342222|refseq:NP_057197.2|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR005821(Ion transport)|interpro:IPR008347(Vanilloid receptor)|interpro:IPR020683|interpro:IPR024862|interpro:IPR024865|interpro:IPR036770|rcsb pdb:2F37|reactome:R-HSA-3295583	-	-	-	figure legend:f1b st1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2021/03/31	2021/07/20	rogid:aaI+D/4SJcwZxWqoxDJ81dA60nU9606	rogid:smxT031fzXTNEj25CzwF+DhPE0o9606	rigid:8TLI9bATGVOgkjT7EFswaZ0AhjA	false	nubg:c-c	cub:c-c	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q6ZSJ9	uniprotkb:Q9Y5S1	intact:EBI-12037847|ensembl:ENSP00000387157|uniprotkb:B3KXV5|uniprotkb:Q4PL63	intact:EBI-11721896|intact:EBI-28973157|ensembl:ENSP00000342222|uniprotkb:A6NML2|uniprotkb:A8K0Z0|uniprotkb:Q9Y670	psi-mi:shsa6_human(display_long)|uniprotkb:SHISA6(gene name)|psi-mi:SHISA6(display_short)	psi-mi:trpv2_human(display_long)|uniprotkb:TRPV2(gene name)|psi-mi:TRPV2(display_short)|uniprotkb:VRL(gene name synonym)|uniprotkb:Osm-9-like TRP channel 2(gene name synonym)|uniprotkb:Vanilloid receptor-like protein 1(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Doñate-Macián et al. (2018)	imex:IM-28838|pubmed:29719613	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26900728|imex:IM-28838-35	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000188803(gene)|ensembl:ENST00000409168(transcript)|go:"GO:0007283"(spermatogenesis)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098976"(excitatory chemical synaptic transmission)|go:"GO:0098985"(asymmetric, glutamatergic, excitatory synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:1904717"(regulation of AMPA glutamate receptor clustering)|go:"GO:2000311"(regulation of AMPA receptor activity)|interpro:IPR026910|refseq:NP_001166932.1|refseq:NP_001166933.1|refseq:NP_997269.2	ensembl:ENSG00000187688(gene)|ensembl:ENST00000338560(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007600"(sensory perception)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009408"(response to heat)|go:"GO:0009986"(cell surface)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042470"(melanosome)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044297"(cell body)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0070588"(calcium ion transmembrane transport)|ensembl:ENSP00000342222|refseq:NP_057197.2|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR005821(Ion transport)|interpro:IPR008347(Vanilloid receptor)|interpro:IPR020683|interpro:IPR024862|interpro:IPR024865|interpro:IPR036770|rcsb pdb:2F37|reactome:R-HSA-3295583	-	-	-	figure legend:f1b st1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2021/03/31	2021/07/20	rogid:XLGs+dNvfiVmXNpAusWX8dOoJQA9606	rogid:smxT031fzXTNEj25CzwF+DhPE0o9606	rigid:h22Zuy7RYBH+jZ49VZzSpR9QMH8	false	nubg:c-c	cub:c-c	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9NXU5	uniprotkb:Q9Y5S1	intact:EBI-711759|uniprotkb:Q6IAD0|ensembl:ENSP00000433427	intact:EBI-11721896|intact:EBI-28973157|ensembl:ENSP00000342222|uniprotkb:A6NML2|uniprotkb:A8K0Z0|uniprotkb:Q9Y670	psi-mi:arl15_human(display_long)|uniprotkb:ADP-ribosylation factor-related protein 2(gene name synonym)|uniprotkb:ARL15(gene name)|psi-mi:ARL15(display_short)|uniprotkb:ARFRP2(gene name synonym)	psi-mi:trpv2_human(display_long)|uniprotkb:TRPV2(gene name)|psi-mi:TRPV2(display_short)|uniprotkb:VRL(gene name synonym)|uniprotkb:Osm-9-like TRP channel 2(gene name synonym)|uniprotkb:Vanilloid receptor-like protein 1(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Doñate-Macián et al. (2018)	imex:IM-28838|pubmed:29719613	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26900736|imex:IM-28838-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061960.1|ensembl:ENSG00000185305(gene)|ensembl:ENST00000504924(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR042292	ensembl:ENSG00000187688(gene)|ensembl:ENST00000338560(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007600"(sensory perception)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009408"(response to heat)|go:"GO:0009986"(cell surface)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042470"(melanosome)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044297"(cell body)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0070588"(calcium ion transmembrane transport)|ensembl:ENSP00000342222|refseq:NP_057197.2|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR005821(Ion transport)|interpro:IPR008347(Vanilloid receptor)|interpro:IPR020683|interpro:IPR024862|interpro:IPR024865|interpro:IPR036770|rcsb pdb:2F37|reactome:R-HSA-3295583	-	-	-	figure legend:f1b st1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2021/03/31	2021/07/20	rogid:8+lfy1NX3BMoln4dph9wrcIm+0M9606	rogid:smxT031fzXTNEj25CzwF+DhPE0o9606	rigid:O9TTOx1M2Gl0J2H9O9zqVpfwkbc	false	nubg:c-c	cub:c-c	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P47895	uniprotkb:Q9Y5S1	intact:EBI-21573752|uniprotkb:Q6NT64|ensembl:ENSP00000332256	intact:EBI-11721896|intact:EBI-28973157|ensembl:ENSP00000342222|uniprotkb:A6NML2|uniprotkb:A8K0Z0|uniprotkb:Q9Y670	psi-mi:al1a3_human(display_long)|uniprotkb:Aldehyde dehydrogenase 6(gene name synonym)|uniprotkb:Retinaldehyde dehydrogenase 3(gene name synonym)|uniprotkb:ALDH1A3(gene name)|psi-mi:ALDH1A3(display_short)|uniprotkb:ALDH6(gene name synonym)	psi-mi:trpv2_human(display_long)|uniprotkb:TRPV2(gene name)|psi-mi:TRPV2(display_short)|uniprotkb:VRL(gene name synonym)|uniprotkb:Osm-9-like TRP channel 2(gene name synonym)|uniprotkb:Vanilloid receptor-like protein 1(gene name synonym)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Doñate-Macián et al. (2018)	imex:IM-28838|pubmed:29719613	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26900744|imex:IM-28838-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000684.2|refseq:NP_001280744.1|go:"GO:0004030"("aldehyde dehydrogenase [NAD(P)+] activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007626"(locomotory behavior)|go:"GO:0021768"(nucleus accumbens development)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042572"(retinol metabolic process)|go:"GO:0042573"(retinoic acid metabolic process)|go:"GO:0042574"(retinal metabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048048"(embryonic eye morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060013"(righting reflex)|go:"GO:0060166"(olfactory pit development)|go:"GO:0060324"(face development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070324"(thyroid hormone binding)|go:"GO:0070384"(Harderian gland development)|go:"GO:0070403"(NAD+ binding)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|rcsb pdb:5FHZ|rcsb pdb:6S6W|rcsb pdb:6TE5|rcsb pdb:6TGW|rcsb pdb:6TRY|rcsb pdb:7A6Q|reactome:R-HSA-5365859|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|ensembl:ENSG00000184254(gene)|ensembl:ENST00000329841(transcript)|go:"GO:0001758"(retinal dehydrogenase activity)|go:"GO:0002072"(optic cup morphogenesis involved in camera-type eye development)|go:"GO:0002138"(retinoic acid biosynthetic process)	ensembl:ENSG00000187688(gene)|ensembl:ENST00000338560(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007600"(sensory perception)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009408"(response to heat)|go:"GO:0009986"(cell surface)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042470"(melanosome)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044297"(cell body)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0070588"(calcium ion transmembrane transport)|ensembl:ENSP00000342222|refseq:NP_057197.2|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR005821(Ion transport)|interpro:IPR008347(Vanilloid receptor)|interpro:IPR020683|interpro:IPR024862|interpro:IPR024865|interpro:IPR036770|rcsb pdb:2F37|reactome:R-HSA-3295583	-	-	-	figure legend:f1b st1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2021/03/31	2021/07/20	rogid:IXQ56uxVqM92z+jRKUeqVGfwImM9606	rogid:smxT031fzXTNEj25CzwF+DhPE0o9606	rigid:GTi8gNBUWC1+s/GAzju4ku9DpTk	false	nubg:c-c	cub:c-c	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O35433	uniprotkb:Q925C0	intact:EBI-2794004|uniprotkb:Q920B3|uniprotkb:Q920B4|uniprotkb:Q9JLM0|uniprotkb:Q9JM56|uniprotkb:Q9JM57|ensembl:ENSRNOP00000026493	intact:EBI-458115|uniprotkb:Q62748|ensembl:ENSRNOP00000026607	psi-mi:trpv1_rat(display_long)|uniprotkb:Trpv1(gene name)|psi-mi:Trpv1(display_short)|uniprotkb:Vr1(gene name synonym)|uniprotkb:Vr1l(gene name synonym)|uniprotkb:Osm-9-like TRP channel 1(gene name synonym)|uniprotkb:Vanilloid receptor 1(gene name synonym)|uniprotkb:Vanilloid receptor type 1-like(gene name synonym)|uniprotkb:Capsaicin receptor(gene name synonym)	psi-mi:syt9_rat(display_long)|uniprotkb:Syt9(gene name)|psi-mi:Syt9(display_short)|uniprotkb:Syt5(gene name synonym)|uniprotkb:Synaptotagmin IX(gene name synonym)|uniprotkb:Synaptotagmin V(gene name synonym)|uniprotkb:Synaptotagmin 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Doñate-Macián et al. (2018)	imex:IM-28838|pubmed:29719613	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26900760|imex:IM-28838-47	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:628841|refseq:NP_114188.1|go:"GO:0002024"(diet induced thermogenesis)|go:"GO:0002790"(peptide secretion)|go:"GO:0003085"(negative regulation of systemic arterial blood pressure)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005230"(extracellular ligand-gated ion channel activity)|go:"GO:0005231"(excitatory extracellular ligand-gated ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006954"(inflammatory response)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0009268"(response to pH)|go:"GO:0009408"(response to heat)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0014047"(glutamate secretion)|ensembl:ENSRNOG00000019486(gene)|go:"GO:0014832"(urinary bladder smooth muscle contraction)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0015278"(calcium-release channel activity)|ensembl:ENSRNOT00000026493(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001660"(fever generation)|go:"GO:0001774"(microglial cell activation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030425"(dendrite)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048265"(response to pain)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0050954"(sensory perception of mechanical stimulus)|go:"GO:0050955"(thermoception)|go:"GO:0050960"(detection of temperature stimulus involved in thermoception)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0050968"(detection of chemical stimulus involved in sensory perception of pain)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071312"(cellular response to alkaloid)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071468"(cellular response to acidic pH)|go:"GO:0071502"(cellular response to temperature stimulus)|go:"GO:0090212"(negative regulation of establishment of blood-brain barrier)|go:"GO:0097603"(temperature-gated ion channel activity)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:1901594"(response to capsazepine)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR002110(Ankyrin)|interpro:IPR005821(Ion transport)|interpro:IPR008347(Vanilloid receptor)|interpro:IPR024862|interpro:IPR024863|interpro:IPR036770|rcsb pdb:2NYJ|rcsb pdb:2PNN|rcsb pdb:3J5P|rcsb pdb:3J5Q|rcsb pdb:3J5R|rcsb pdb:3J9J|rcsb pdb:3SUI|rcsb pdb:5IRX|rcsb pdb:5IRZ|rcsb pdb:5IS0|reactome:R-RNO-3295583|interpro:IPR020683|dip:DIP-56949N	go:"GO:0042802"(identical protein binding)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0099502"(calcium-dependent activation of synaptic vesicle fusion)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001565(Synaptotagmin)|interpro:IPR028691|interpro:IPR035892|reactome:R-RNO-8856825|reactome:R-RNO-8856828|ensembl:ENSRNOG00000019613(gene)|ensembl:ENSRNOT00000026607(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017158"(regulation of calcium ion-dependent exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030276"(clathrin binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031045"(dense core granule)|rgd:621169|refseq:NP_445776.1	-	-	-	figure legend:f1a|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2021/03/31	2021/03/31	rogid:LnpGgt/1oao2D+KpsL3tm9TcNx010116	rogid:v880S2MBvWsOTw2bEUSu2suJjRc10116	rigid:507eSD7l3PokLXfQJwtNuIKvVAM	false	tandem tag:c-c	myc tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O35433	uniprotkb:P60192	intact:EBI-2794004|uniprotkb:Q920B3|uniprotkb:Q920B4|uniprotkb:Q9JLM0|uniprotkb:Q9JM56|uniprotkb:Q9JM57|ensembl:ENSRNOP00000026493	intact:EBI-917825|ensembl:ENSRNOP00000018830	psi-mi:trpv1_rat(display_long)|uniprotkb:Trpv1(gene name)|psi-mi:Trpv1(display_short)|uniprotkb:Vr1(gene name synonym)|uniprotkb:Vr1l(gene name synonym)|uniprotkb:Osm-9-like TRP channel 1(gene name synonym)|uniprotkb:Vanilloid receptor 1(gene name synonym)|uniprotkb:Vanilloid receptor type 1-like(gene name synonym)|uniprotkb:Capsaicin receptor(gene name synonym)	psi-mi:snapn_rat(display_long)|uniprotkb:Snapap(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:Snapin(gene name)|psi-mi:Snapin(display_short)|uniprotkb:Snap25bp(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)|uniprotkb:Bloc1s7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Doñate-Macián et al. (2018)	imex:IM-28838|pubmed:29719613	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26900768|imex:IM-28838-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:628841|refseq:NP_114188.1|go:"GO:0002024"(diet induced thermogenesis)|go:"GO:0002790"(peptide secretion)|go:"GO:0003085"(negative regulation of systemic arterial blood pressure)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005230"(extracellular ligand-gated ion channel activity)|go:"GO:0005231"(excitatory extracellular ligand-gated ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006954"(inflammatory response)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008324"(cation transmembrane transporter activity)|go:"GO:0009268"(response to pH)|go:"GO:0009408"(response to heat)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0014047"(glutamate secretion)|ensembl:ENSRNOG00000019486(gene)|go:"GO:0014832"(urinary bladder smooth muscle contraction)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0015278"(calcium-release channel activity)|ensembl:ENSRNOT00000026493(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001660"(fever generation)|go:"GO:0001774"(microglial cell activation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030425"(dendrite)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048265"(response to pain)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0050954"(sensory perception of mechanical stimulus)|go:"GO:0050955"(thermoception)|go:"GO:0050960"(detection of temperature stimulus involved in thermoception)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0050968"(detection of chemical stimulus involved in sensory perception of pain)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071312"(cellular response to alkaloid)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071468"(cellular response to acidic pH)|go:"GO:0071502"(cellular response to temperature stimulus)|go:"GO:0090212"(negative regulation of establishment of blood-brain barrier)|go:"GO:0097603"(temperature-gated ion channel activity)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:1901594"(response to capsazepine)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR002110(Ankyrin)|interpro:IPR005821(Ion transport)|interpro:IPR008347(Vanilloid receptor)|interpro:IPR024862|interpro:IPR024863|interpro:IPR036770|rcsb pdb:2NYJ|rcsb pdb:2PNN|rcsb pdb:3J5P|rcsb pdb:3J5Q|rcsb pdb:3J5R|rcsb pdb:3J9J|rcsb pdb:3SUI|rcsb pdb:5IRX|rcsb pdb:5IRZ|rcsb pdb:5IS0|reactome:R-RNO-3295583|interpro:IPR020683|dip:DIP-56949N	rgd:1560377|refseq:NP_001164047.1|ensembl:ENSRNOG00000013356(gene)|ensembl:ENSRNOT00000018830(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|mint:P60192|reactome:R-RNO-432722	-	-	-	figure legend:f1a|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2021/03/31	2021/03/31	rogid:LnpGgt/1oao2D+KpsL3tm9TcNx010116	rogid:L66mKyBsv3V0+K6AhcHvc540uX810116	rigid:qn2P8cHf9TwcUK/UGzqSZ1XEpXM	false	tandem tag:c-c	myc tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9WUD2	uniprotkb:P60192	intact:EBI-11689641|uniprotkb:Q5FWT3|uniprotkb:Q9JMI8|uniprotkb:Q9QYH8	intact:EBI-917825|ensembl:ENSRNOP00000018830	psi-mi:trpv2_rat(display_long)|uniprotkb:Osm-9-like TRP channel 2(gene name synonym)|uniprotkb:Stretch-activated channel 2B(gene name synonym)|uniprotkb:Vanilloid receptor-like protein 1(gene name synonym)|uniprotkb:Trpv2(gene name)|psi-mi:Trpv2(display_short)|uniprotkb:Sac2b(gene name synonym)|uniprotkb:Vrl1(gene name synonym)	psi-mi:snapn_rat(display_long)|uniprotkb:Snapap(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:Snapin(gene name)|psi-mi:Snapin(display_short)|uniprotkb:Snap25bp(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym)|uniprotkb:Bloc1s7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Doñate-Macián et al. (2018)	imex:IM-28838|pubmed:29719613	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26900776|imex:IM-28838-37	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001257726.1|refseq:NP_001257727.1|refseq:NP_058903.2|rgd:3965|reactome:R-RNO-3295583|go:"GO:0005216"(ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009408"(response to heat)|go:"GO:0009986"(cell surface)|go:"GO:0012505"(endomembrane system)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044297"(cell body)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR005821(Ion transport)|interpro:IPR008347(Vanilloid receptor)|interpro:IPR020683|interpro:IPR024862|interpro:IPR024865|interpro:IPR036770|rcsb pdb:2ETA|rcsb pdb:2ETB|rcsb pdb:2ETC|rcsb pdb:5HI9|rcsb pdb:6BO4|rcsb pdb:6BO5|rcsb pdb:6U84|rcsb pdb:6U86|rcsb pdb:6U88|rcsb pdb:6U8A|rcsb pdb:6WKN|dip:DIP-60657N	rgd:1560377|refseq:NP_001164047.1|ensembl:ENSRNOG00000013356(gene)|ensembl:ENSRNOT00000018830(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|mint:P60192|reactome:R-RNO-432722	-	-	-	figure legend:f1a|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2021/03/31	2021/03/31	rogid:lmBouFrPwj7YSAWYnLBXqCUcFV010116	rogid:L66mKyBsv3V0+K6AhcHvc540uX810116	rigid:yjrxrJj9c3c7djkmXQefBIXDePw	false	tandem tag:c-c	myc tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9WUD2	uniprotkb:Q925C0	intact:EBI-11689641|uniprotkb:Q5FWT3|uniprotkb:Q9JMI8|uniprotkb:Q9QYH8	intact:EBI-458115|uniprotkb:Q62748|ensembl:ENSRNOP00000026607	psi-mi:trpv2_rat(display_long)|uniprotkb:Osm-9-like TRP channel 2(gene name synonym)|uniprotkb:Stretch-activated channel 2B(gene name synonym)|uniprotkb:Vanilloid receptor-like protein 1(gene name synonym)|uniprotkb:Trpv2(gene name)|psi-mi:Trpv2(display_short)|uniprotkb:Sac2b(gene name synonym)|uniprotkb:Vrl1(gene name synonym)	psi-mi:syt9_rat(display_long)|uniprotkb:Syt9(gene name)|psi-mi:Syt9(display_short)|uniprotkb:Syt5(gene name synonym)|uniprotkb:Synaptotagmin IX(gene name synonym)|uniprotkb:Synaptotagmin V(gene name synonym)|uniprotkb:Synaptotagmin 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Doñate-Macián et al. (2018)	imex:IM-28838|pubmed:29719613	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26900784|imex:IM-28838-39	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001257726.1|refseq:NP_001257727.1|refseq:NP_058903.2|rgd:3965|reactome:R-RNO-3295583|go:"GO:0005216"(ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009266"(response to temperature stimulus)|go:"GO:0009408"(response to heat)|go:"GO:0009986"(cell surface)|go:"GO:0012505"(endomembrane system)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044297"(cell body)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR002110(Ankyrin)|interpro:IPR005821(Ion transport)|interpro:IPR008347(Vanilloid receptor)|interpro:IPR020683|interpro:IPR024862|interpro:IPR024865|interpro:IPR036770|rcsb pdb:2ETA|rcsb pdb:2ETB|rcsb pdb:2ETC|rcsb pdb:5HI9|rcsb pdb:6BO4|rcsb pdb:6BO5|rcsb pdb:6U84|rcsb pdb:6U86|rcsb pdb:6U88|rcsb pdb:6U8A|rcsb pdb:6WKN|dip:DIP-60657N	go:"GO:0042802"(identical protein binding)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0099502"(calcium-dependent activation of synaptic vesicle fusion)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001565(Synaptotagmin)|interpro:IPR028691|interpro:IPR035892|reactome:R-RNO-8856825|reactome:R-RNO-8856828|ensembl:ENSRNOG00000019613(gene)|ensembl:ENSRNOT00000026607(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017158"(regulation of calcium ion-dependent exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030276"(clathrin binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031045"(dense core granule)|rgd:621169|refseq:NP_445776.1	-	-	-	figure legend:f1a|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2021/03/31	2021/03/31	rogid:lmBouFrPwj7YSAWYnLBXqCUcFV010116	rogid:v880S2MBvWsOTw2bEUSu2suJjRc10116	rigid:JmDQFQPYUkf1c67XtRMm0Xn1NPY	false	tandem tag:c-c	myc tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)