#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q60793 uniprotkb:Q501J6 intact:EBI-3043905|ensembl:ENSMUSP00000103245|uniprotkb:P70421|uniprotkb:Q3U2D6|uniprotkb:Q3URS6|uniprotkb:Q78K30|uniprotkb:Q9R255 intact:EBI-911206|uniprotkb:Q6P5G1|uniprotkb:Q8BIN2|ensembl:ENSMUSP00000155307 psi-mi:klf4_mouse(display_long)|uniprotkb:Klf4(gene name)|psi-mi:Klf4(display_short)|uniprotkb:Ezf(gene name synonym)|uniprotkb:Gklf(gene name synonym)|uniprotkb:Zie(gene name synonym)|uniprotkb:Epithelial zinc finger protein EZF(gene name synonym)|uniprotkb:Gut-enriched krueppel-like factor(gene name synonym) psi-mi:ddx17_mouse(display_long)|uniprotkb:DEAD box protein 17(gene name synonym)|uniprotkb:Ddx17(gene name)|psi-mi:Ddx17(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Moon et al. (2018) imex:IM-28837|pubmed:29374155 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26900388|imex:IM-28837-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000107619(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001010"(RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010033"(response to organic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014740"(negative regulation of muscle hyperplasia)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030154"(cell differentiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031077"(post-embryonic camera-type eye development)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|ensembl:ENSMUSG00000003032(gene)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071409"(cellular response to cycloheximide)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0120222"(regulation of blastocyst development)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904998"(negative regulation of leukocyte adhesion to arterial endothelial cell)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:2WBS|rcsb pdb:2WBU|rcsb pdb:4M9E|rcsb pdb:5KE6|rcsb pdb:5KE7|rcsb pdb:5KE8|rcsb pdb:5KE9|rcsb pdb:5KEA|rcsb pdb:5KEB|go:"GO:0051973"(positive regulation of telomerase activity)|refseq:NP_034767.2|dip:DIP-59920N refseq:NP_001035277.1|refseq:NP_951061.1|refseq:NP_951062.1|ensembl:ENSMUSG00000055065(gene)|ensembl:ENSMUST00000229877(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006364"(rRNA processing)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:0061614"(miRNA transcription)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q501J6|reactome:R-MMU-3899300 - - - figure legend:f3c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2021/03/31 2021/04/27 rogid:g++XMPgXaBO9C3bV8RbenG3JTxQ10090 rogid:uGXMsVmy7MWcTaJPNlkof05dS8I10090 rigid:iQoJRoBxIioemqsCeZsBMxip8p8 false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q60793 uniprotkb:Q61656 intact:EBI-3043905|ensembl:ENSMUSP00000103245|uniprotkb:P70421|uniprotkb:Q3U2D6|uniprotkb:Q3URS6|uniprotkb:Q78K30|uniprotkb:Q9R255 intact:EBI-643076|uniprotkb:E9Q105 psi-mi:klf4_mouse(display_long)|uniprotkb:Klf4(gene name)|psi-mi:Klf4(display_short)|uniprotkb:Ezf(gene name synonym)|uniprotkb:Gklf(gene name synonym)|uniprotkb:Zie(gene name synonym)|uniprotkb:Epithelial zinc finger protein EZF(gene name synonym)|uniprotkb:Gut-enriched krueppel-like factor(gene name synonym) psi-mi:ddx5_mouse(display_long)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:RNA helicase p68(gene name synonym)|uniprotkb:DEAD box RNA helicase DEAD1(gene name synonym)|uniprotkb:Ddx5(gene name)|psi-mi:Ddx5(display_short)|uniprotkb:Tnz2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Moon et al. (2018) imex:IM-28837|pubmed:29374155 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26900388|imex:IM-28837-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000107619(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001010"(RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010033"(response to organic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014740"(negative regulation of muscle hyperplasia)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030154"(cell differentiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031077"(post-embryonic camera-type eye development)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|ensembl:ENSMUSG00000003032(gene)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071409"(cellular response to cycloheximide)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0120222"(regulation of blastocyst development)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904998"(negative regulation of leukocyte adhesion to arterial endothelial cell)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:2WBS|rcsb pdb:2WBU|rcsb pdb:4M9E|rcsb pdb:5KE6|rcsb pdb:5KE7|rcsb pdb:5KE8|rcsb pdb:5KE9|rcsb pdb:5KEA|rcsb pdb:5KEB|go:"GO:0051973"(positive regulation of telomerase activity)|refseq:NP_034767.2|dip:DIP-59920N interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012587(P68HR)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-MMU-3899300|reactome:R-MMU-72163|reactome:R-MMU-9018519|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009299"(mRNA transcription)|go:"GO:0019899"(enzyme binding)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061614"(miRNA transcription)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|dip:DIP-32293N|mint:Q61656 - - - figure legend:f3c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2021/03/31 2021/04/27 rogid:g++XMPgXaBO9C3bV8RbenG3JTxQ10090 rogid:X5OQN/Gdq852njTrHnlDliAjrQY10090 rigid:iQoJRoBxIioemqsCeZsBMxip8p8 false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q60793 uniprotkb:O95793 intact:EBI-3043905|ensembl:ENSMUSP00000103245|uniprotkb:P70421|uniprotkb:Q3U2D6|uniprotkb:Q3URS6|uniprotkb:Q78K30|uniprotkb:Q9R255 intact:EBI-358174|uniprotkb:Q6GTM4|uniprotkb:Q9H5B5|intact:EBI-366174|uniprotkb:Q9H5B4|uniprotkb:Q9Y3Q2|uniprotkb:A8K9Z4|ensembl:ENSP00000360922|uniprotkb:E1P5Y1|uniprotkb:E1P608|uniprotkb:Q5JW29 psi-mi:klf4_mouse(display_long)|uniprotkb:Klf4(gene name)|psi-mi:Klf4(display_short)|uniprotkb:Ezf(gene name synonym)|uniprotkb:Gklf(gene name synonym)|uniprotkb:Zie(gene name synonym)|uniprotkb:Epithelial zinc finger protein EZF(gene name synonym)|uniprotkb:Gut-enriched krueppel-like factor(gene name synonym) psi-mi:stau1_human(display_long)|uniprotkb:STAU1(gene name)|psi-mi:STAU1(display_short)|uniprotkb:STAU(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Moon et al. (2018) imex:IM-28837|pubmed:29374155 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26900388|imex:IM-28837-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000107619(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001010"(RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010033"(response to organic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014740"(negative regulation of muscle hyperplasia)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030154"(cell differentiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031077"(post-embryonic camera-type eye development)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|ensembl:ENSMUSG00000003032(gene)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071409"(cellular response to cycloheximide)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0120222"(regulation of blastocyst development)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904998"(negative regulation of leukocyte adhesion to arterial endothelial cell)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:2WBS|rcsb pdb:2WBU|rcsb pdb:4M9E|rcsb pdb:5KE6|rcsb pdb:5KE7|rcsb pdb:5KE8|rcsb pdb:5KE9|rcsb pdb:5KEA|rcsb pdb:5KEB|go:"GO:0051973"(positive regulation of telomerase activity)|refseq:NP_034767.2|dip:DIP-59920N refseq:NP_001309856.1|refseq:NP_001309858.1|refseq:NP_001309859.1|refseq:NP_001032405.1|refseq:NP_004593.2|refseq:NP_059346.2|refseq:NP_059347.2|refseq:NP_059348.2|refseq:NP_001306063.1|refseq:NP_001306064.1|ensembl:ENSG00000124214(gene)|ensembl:ENST00000371856(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|refseq:XP_005260584.1|go:"GO:0099010"(modification of postsynaptic structure)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR044475|mint:O95793|rcsb pdb:4DKK|rcsb pdb:6HTU|rcsb pdb:6SDW|rcsb pdb:6SDY - - - figure legend:f3c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2021/03/31 2021/04/27 rogid:g++XMPgXaBO9C3bV8RbenG3JTxQ10090 rogid:uYjbWja/hG5M/3likHLe00Z2FgY9606 rigid:iQoJRoBxIioemqsCeZsBMxip8p8 false flag tag:n-n ha tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O95793 uniprotkb:Q9EPU0 intact:EBI-358174|uniprotkb:Q6GTM4|uniprotkb:Q9H5B5|intact:EBI-366174|uniprotkb:Q9H5B4|uniprotkb:Q9Y3Q2|uniprotkb:A8K9Z4|ensembl:ENSP00000360922|uniprotkb:E1P5Y1|uniprotkb:E1P608|uniprotkb:Q5JW29 intact:EBI-6876715|ensembl:ENSMUSP00000075089|uniprotkb:Q3UG00|uniprotkb:Q6GYP5|uniprotkb:Q6PHQ5|uniprotkb:Q8K0N4|uniprotkb:Q99PR4 psi-mi:stau1_human(display_long)|uniprotkb:STAU1(gene name)|psi-mi:STAU1(display_short)|uniprotkb:STAU(gene name synonym) psi-mi:rent1_mouse(display_long)|uniprotkb:Upf1(gene name)|psi-mi:Upf1(display_short)|uniprotkb:Rent1(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Moon et al. (2018) imex:IM-28837|pubmed:29374155 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26900398|imex:IM-28837-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001309856.1|refseq:NP_001309858.1|refseq:NP_001309859.1|refseq:NP_001032405.1|refseq:NP_004593.2|refseq:NP_059346.2|refseq:NP_059347.2|refseq:NP_059348.2|refseq:NP_001306063.1|refseq:NP_001306064.1|ensembl:ENSG00000124214(gene)|ensembl:ENST00000371856(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|refseq:XP_005260584.1|go:"GO:0099010"(modification of postsynaptic structure)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR044475|mint:O95793|rcsb pdb:4DKK|rcsb pdb:6HTU|rcsb pdb:6SDW|rcsb pdb:6SDY ensembl:ENSMUSG00000058301(gene)|ensembl:ENSMUST00000075666(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR018999|interpro:IPR027417|interpro:IPR040812|interpro:IPR041677|interpro:IPR041679|mint:Q9EPU0|reactome:R-MMU-975956|reactome:R-MMU-975957|go:"GO:0042162"(telomeric DNA binding)|refseq:XP_006509667.1|refseq:XP_006509668.1|refseq:NP_001116301.1|refseq:NP_109605.2|dip:DIP-60114N - - - figure legend:f3d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2021/03/31 2021/04/27 rogid:uYjbWja/hG5M/3likHLe00Z2FgY9606 rogid:rwd4XXdf5Uqjtgao/zILckKP8AM10090 rigid:/IV2bn9NAaWTzT7BjeJ12We7fRc false ha tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O95793 uniprotkb:Q501J6 intact:EBI-358174|uniprotkb:Q6GTM4|uniprotkb:Q9H5B5|intact:EBI-366174|uniprotkb:Q9H5B4|uniprotkb:Q9Y3Q2|uniprotkb:A8K9Z4|ensembl:ENSP00000360922|uniprotkb:E1P5Y1|uniprotkb:E1P608|uniprotkb:Q5JW29 intact:EBI-911206|uniprotkb:Q6P5G1|uniprotkb:Q8BIN2|ensembl:ENSMUSP00000155307 psi-mi:stau1_human(display_long)|uniprotkb:STAU1(gene name)|psi-mi:STAU1(display_short)|uniprotkb:STAU(gene name synonym) psi-mi:ddx17_mouse(display_long)|uniprotkb:DEAD box protein 17(gene name synonym)|uniprotkb:Ddx17(gene name)|psi-mi:Ddx17(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Moon et al. (2018) imex:IM-28837|pubmed:29374155 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26900398|imex:IM-28837-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001309856.1|refseq:NP_001309858.1|refseq:NP_001309859.1|refseq:NP_001032405.1|refseq:NP_004593.2|refseq:NP_059346.2|refseq:NP_059347.2|refseq:NP_059348.2|refseq:NP_001306063.1|refseq:NP_001306064.1|ensembl:ENSG00000124214(gene)|ensembl:ENST00000371856(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|refseq:XP_005260584.1|go:"GO:0099010"(modification of postsynaptic structure)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR044475|mint:O95793|rcsb pdb:4DKK|rcsb pdb:6HTU|rcsb pdb:6SDW|rcsb pdb:6SDY refseq:NP_001035277.1|refseq:NP_951061.1|refseq:NP_951062.1|ensembl:ENSMUSG00000055065(gene)|ensembl:ENSMUST00000229877(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006364"(rRNA processing)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:0061614"(miRNA transcription)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q501J6|reactome:R-MMU-3899300 - - - figure legend:f3d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2021/03/31 2021/04/27 rogid:uYjbWja/hG5M/3likHLe00Z2FgY9606 rogid:uGXMsVmy7MWcTaJPNlkof05dS8I10090 rigid:/IV2bn9NAaWTzT7BjeJ12We7fRc false ha tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O95793 uniprotkb:Q61656 intact:EBI-358174|uniprotkb:Q6GTM4|uniprotkb:Q9H5B5|intact:EBI-366174|uniprotkb:Q9H5B4|uniprotkb:Q9Y3Q2|uniprotkb:A8K9Z4|ensembl:ENSP00000360922|uniprotkb:E1P5Y1|uniprotkb:E1P608|uniprotkb:Q5JW29 intact:EBI-643076|uniprotkb:E9Q105 psi-mi:stau1_human(display_long)|uniprotkb:STAU1(gene name)|psi-mi:STAU1(display_short)|uniprotkb:STAU(gene name synonym) psi-mi:ddx5_mouse(display_long)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:RNA helicase p68(gene name synonym)|uniprotkb:DEAD box RNA helicase DEAD1(gene name synonym)|uniprotkb:Ddx5(gene name)|psi-mi:Ddx5(display_short)|uniprotkb:Tnz2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Moon et al. (2018) imex:IM-28837|pubmed:29374155 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26900398|imex:IM-28837-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001309856.1|refseq:NP_001309858.1|refseq:NP_001309859.1|refseq:NP_001032405.1|refseq:NP_004593.2|refseq:NP_059346.2|refseq:NP_059347.2|refseq:NP_059348.2|refseq:NP_001306063.1|refseq:NP_001306064.1|ensembl:ENSG00000124214(gene)|ensembl:ENST00000371856(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|refseq:XP_005260584.1|go:"GO:0099010"(modification of postsynaptic structure)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR044475|mint:O95793|rcsb pdb:4DKK|rcsb pdb:6HTU|rcsb pdb:6SDW|rcsb pdb:6SDY interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012587(P68HR)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-MMU-3899300|reactome:R-MMU-72163|reactome:R-MMU-9018519|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009299"(mRNA transcription)|go:"GO:0019899"(enzyme binding)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061614"(miRNA transcription)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|dip:DIP-32293N|mint:Q61656 - - - figure legend:f3d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2021/03/31 2021/04/27 rogid:uYjbWja/hG5M/3likHLe00Z2FgY9606 rogid:X5OQN/Gdq852njTrHnlDliAjrQY10090 rigid:/IV2bn9NAaWTzT7BjeJ12We7fRc false ha tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O95793 uniprotkb:Q60793 intact:EBI-358174|uniprotkb:Q6GTM4|uniprotkb:Q9H5B5|intact:EBI-366174|uniprotkb:Q9H5B4|uniprotkb:Q9Y3Q2|uniprotkb:A8K9Z4|ensembl:ENSP00000360922|uniprotkb:E1P5Y1|uniprotkb:E1P608|uniprotkb:Q5JW29 intact:EBI-3043905|ensembl:ENSMUSP00000103245|uniprotkb:P70421|uniprotkb:Q3U2D6|uniprotkb:Q3URS6|uniprotkb:Q78K30|uniprotkb:Q9R255 psi-mi:stau1_human(display_long)|uniprotkb:STAU1(gene name)|psi-mi:STAU1(display_short)|uniprotkb:STAU(gene name synonym) psi-mi:klf4_mouse(display_long)|uniprotkb:Klf4(gene name)|psi-mi:Klf4(display_short)|uniprotkb:Ezf(gene name synonym)|uniprotkb:Gklf(gene name synonym)|uniprotkb:Zie(gene name synonym)|uniprotkb:Epithelial zinc finger protein EZF(gene name synonym)|uniprotkb:Gut-enriched krueppel-like factor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Moon et al. (2018) imex:IM-28837|pubmed:29374155 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26900398|imex:IM-28837-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001309856.1|refseq:NP_001309858.1|refseq:NP_001309859.1|refseq:NP_001032405.1|refseq:NP_004593.2|refseq:NP_059346.2|refseq:NP_059347.2|refseq:NP_059348.2|refseq:NP_001306063.1|refseq:NP_001306064.1|ensembl:ENSG00000124214(gene)|ensembl:ENST00000371856(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|refseq:XP_005260584.1|go:"GO:0099010"(modification of postsynaptic structure)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR044475|mint:O95793|rcsb pdb:4DKK|rcsb pdb:6HTU|rcsb pdb:6SDW|rcsb pdb:6SDY ensembl:ENSMUST00000107619(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001010"(RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010033"(response to organic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014740"(negative regulation of muscle hyperplasia)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030154"(cell differentiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031077"(post-embryonic camera-type eye development)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|ensembl:ENSMUSG00000003032(gene)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071409"(cellular response to cycloheximide)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0120222"(regulation of blastocyst development)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904998"(negative regulation of leukocyte adhesion to arterial endothelial cell)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:2WBS|rcsb pdb:2WBU|rcsb pdb:4M9E|rcsb pdb:5KE6|rcsb pdb:5KE7|rcsb pdb:5KE8|rcsb pdb:5KE9|rcsb pdb:5KEA|rcsb pdb:5KEB|go:"GO:0051973"(positive regulation of telomerase activity)|refseq:NP_034767.2|dip:DIP-59920N - - - figure legend:f3d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2021/03/31 2021/04/27 rogid:uYjbWja/hG5M/3likHLe00Z2FgY9606 rogid:g++XMPgXaBO9C3bV8RbenG3JTxQ10090 rigid:/IV2bn9NAaWTzT7BjeJ12We7fRc false ha tag:c-c flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q60793 uniprotkb:Q9Z108 intact:EBI-3043905|ensembl:ENSMUSP00000103245|uniprotkb:P70421|uniprotkb:Q3U2D6|uniprotkb:Q3URS6|uniprotkb:Q78K30|uniprotkb:Q9R255 intact:EBI-8020609|intact:UNK-5561237|ensembl:ENSMUSP00000104859 psi-mi:klf4_mouse(display_long)|uniprotkb:Klf4(gene name)|psi-mi:Klf4(display_short)|uniprotkb:Ezf(gene name synonym)|uniprotkb:Gklf(gene name synonym)|uniprotkb:Zie(gene name synonym)|uniprotkb:Epithelial zinc finger protein EZF(gene name synonym)|uniprotkb:Gut-enriched krueppel-like factor(gene name synonym) psi-mi:stau1_mouse(display_long)|uniprotkb:Stau1(gene name)|psi-mi:Stau1(display_short)|uniprotkb:Stau(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Moon et al. (2018) imex:IM-28837|pubmed:29374155 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26900467|imex:IM-28837-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000107619(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001010"(RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010033"(response to organic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014740"(negative regulation of muscle hyperplasia)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030154"(cell differentiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031077"(post-embryonic camera-type eye development)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|ensembl:ENSMUSG00000003032(gene)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071409"(cellular response to cycloheximide)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0120222"(regulation of blastocyst development)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904998"(negative regulation of leukocyte adhesion to arterial endothelial cell)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:2WBS|rcsb pdb:2WBU|rcsb pdb:4M9E|rcsb pdb:5KE6|rcsb pdb:5KE7|rcsb pdb:5KE8|rcsb pdb:5KE9|rcsb pdb:5KEA|rcsb pdb:5KEB|go:"GO:0051973"(positive regulation of telomerase activity)|refseq:NP_034767.2|dip:DIP-59920N refseq:NP_035620.1|ensembl:ENSMUSG00000039536(gene)|ensembl:ENSMUST00000109236(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030425"(dendrite)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099010"(modification of postsynaptic structure)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR044475|mint:Q9Z108 - - comment:mint|function:"Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site" figure legend:f3h|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2021/03/31 2021/03/31 rogid:g++XMPgXaBO9C3bV8RbenG3JTxQ10090 rogid:9zPJq1T9MxPD12EiZZWLuRcCpTk10090 rigid:AnJ4awhSquwfq0ZXPeQAUNmwUhQ false flag tag:n-n|necessary binding region:402-483 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q60793 uniprotkb:Q501J6 intact:EBI-3043905|ensembl:ENSMUSP00000103245|uniprotkb:P70421|uniprotkb:Q3U2D6|uniprotkb:Q3URS6|uniprotkb:Q78K30|uniprotkb:Q9R255 intact:EBI-911206|uniprotkb:Q6P5G1|uniprotkb:Q8BIN2|ensembl:ENSMUSP00000155307 psi-mi:klf4_mouse(display_long)|uniprotkb:Klf4(gene name)|psi-mi:Klf4(display_short)|uniprotkb:Ezf(gene name synonym)|uniprotkb:Gklf(gene name synonym)|uniprotkb:Zie(gene name synonym)|uniprotkb:Epithelial zinc finger protein EZF(gene name synonym)|uniprotkb:Gut-enriched krueppel-like factor(gene name synonym) psi-mi:ddx17_mouse(display_long)|uniprotkb:DEAD box protein 17(gene name synonym)|uniprotkb:Ddx17(gene name)|psi-mi:Ddx17(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Moon et al. (2018) imex:IM-28837|pubmed:29374155 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26900467|imex:IM-28837-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000107619(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001010"(RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010033"(response to organic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014740"(negative regulation of muscle hyperplasia)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030154"(cell differentiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031077"(post-embryonic camera-type eye development)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|ensembl:ENSMUSG00000003032(gene)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071409"(cellular response to cycloheximide)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0120222"(regulation of blastocyst development)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904998"(negative regulation of leukocyte adhesion to arterial endothelial cell)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:2WBS|rcsb pdb:2WBU|rcsb pdb:4M9E|rcsb pdb:5KE6|rcsb pdb:5KE7|rcsb pdb:5KE8|rcsb pdb:5KE9|rcsb pdb:5KEA|rcsb pdb:5KEB|go:"GO:0051973"(positive regulation of telomerase activity)|refseq:NP_034767.2|dip:DIP-59920N refseq:NP_001035277.1|refseq:NP_951061.1|refseq:NP_951062.1|ensembl:ENSMUSG00000055065(gene)|ensembl:ENSMUST00000229877(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006364"(rRNA processing)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:0061614"(miRNA transcription)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q501J6|reactome:R-MMU-3899300 - - - figure legend:f3h|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2021/03/31 2021/03/31 rogid:g++XMPgXaBO9C3bV8RbenG3JTxQ10090 rogid:uGXMsVmy7MWcTaJPNlkof05dS8I10090 rigid:AnJ4awhSquwfq0ZXPeQAUNmwUhQ false flag tag:n-n|necessary binding region:402-483 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q60793 uniprotkb:Q61656 intact:EBI-3043905|ensembl:ENSMUSP00000103245|uniprotkb:P70421|uniprotkb:Q3U2D6|uniprotkb:Q3URS6|uniprotkb:Q78K30|uniprotkb:Q9R255 intact:EBI-643076|uniprotkb:E9Q105 psi-mi:klf4_mouse(display_long)|uniprotkb:Klf4(gene name)|psi-mi:Klf4(display_short)|uniprotkb:Ezf(gene name synonym)|uniprotkb:Gklf(gene name synonym)|uniprotkb:Zie(gene name synonym)|uniprotkb:Epithelial zinc finger protein EZF(gene name synonym)|uniprotkb:Gut-enriched krueppel-like factor(gene name synonym) psi-mi:ddx5_mouse(display_long)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:RNA helicase p68(gene name synonym)|uniprotkb:DEAD box RNA helicase DEAD1(gene name synonym)|uniprotkb:Ddx5(gene name)|psi-mi:Ddx5(display_short)|uniprotkb:Tnz2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Moon et al. (2018) imex:IM-28837|pubmed:29374155 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26900467|imex:IM-28837-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000107619(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001010"(RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010033"(response to organic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014740"(negative regulation of muscle hyperplasia)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030154"(cell differentiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031077"(post-embryonic camera-type eye development)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|ensembl:ENSMUSG00000003032(gene)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071409"(cellular response to cycloheximide)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0120222"(regulation of blastocyst development)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904998"(negative regulation of leukocyte adhesion to arterial endothelial cell)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:2WBS|rcsb pdb:2WBU|rcsb pdb:4M9E|rcsb pdb:5KE6|rcsb pdb:5KE7|rcsb pdb:5KE8|rcsb pdb:5KE9|rcsb pdb:5KEA|rcsb pdb:5KEB|go:"GO:0051973"(positive regulation of telomerase activity)|refseq:NP_034767.2|dip:DIP-59920N interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012587(P68HR)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-MMU-3899300|reactome:R-MMU-72163|reactome:R-MMU-9018519|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009299"(mRNA transcription)|go:"GO:0019899"(enzyme binding)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061614"(miRNA transcription)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|dip:DIP-32293N|mint:Q61656 - - - figure legend:f3h|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2021/03/31 2021/03/31 rogid:g++XMPgXaBO9C3bV8RbenG3JTxQ10090 rogid:X5OQN/Gdq852njTrHnlDliAjrQY10090 rigid:AnJ4awhSquwfq0ZXPeQAUNmwUhQ false flag tag:n-n|necessary binding region:402-483 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q60793 uniprotkb:Q9Z108 intact:EBI-3043905|ensembl:ENSMUSP00000103245|uniprotkb:P70421|uniprotkb:Q3U2D6|uniprotkb:Q3URS6|uniprotkb:Q78K30|uniprotkb:Q9R255 intact:EBI-8020609|intact:UNK-5561237|ensembl:ENSMUSP00000104859 psi-mi:klf4_mouse(display_long)|uniprotkb:Klf4(gene name)|psi-mi:Klf4(display_short)|uniprotkb:Ezf(gene name synonym)|uniprotkb:Gklf(gene name synonym)|uniprotkb:Zie(gene name synonym)|uniprotkb:Epithelial zinc finger protein EZF(gene name synonym)|uniprotkb:Gut-enriched krueppel-like factor(gene name synonym) psi-mi:stau1_mouse(display_long)|uniprotkb:Stau1(gene name)|psi-mi:Stau1(display_short)|uniprotkb:Stau(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Moon et al. (2018) imex:IM-28837|pubmed:29374155 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26900379|imex:IM-28837-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000107619(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001010"(RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010033"(response to organic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014740"(negative regulation of muscle hyperplasia)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030154"(cell differentiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031077"(post-embryonic camera-type eye development)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|ensembl:ENSMUSG00000003032(gene)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071409"(cellular response to cycloheximide)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0120222"(regulation of blastocyst development)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904998"(negative regulation of leukocyte adhesion to arterial endothelial cell)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:2WBS|rcsb pdb:2WBU|rcsb pdb:4M9E|rcsb pdb:5KE6|rcsb pdb:5KE7|rcsb pdb:5KE8|rcsb pdb:5KE9|rcsb pdb:5KEA|rcsb pdb:5KEB|go:"GO:0051973"(positive regulation of telomerase activity)|refseq:NP_034767.2|dip:DIP-59920N refseq:NP_035620.1|ensembl:ENSMUSG00000039536(gene)|ensembl:ENSMUST00000109236(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030425"(dendrite)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099010"(modification of postsynaptic structure)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR044475|mint:Q9Z108 - - comment:mint|function:"Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site" figure legend:f3a sf7e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2021/03/31 2021/03/31 rogid:g++XMPgXaBO9C3bV8RbenG3JTxQ10090 rogid:9zPJq1T9MxPD12EiZZWLuRcCpTk10090 rigid:AnJ4awhSquwfq0ZXPeQAUNmwUhQ false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q60793 uniprotkb:Q501J6 intact:EBI-3043905|ensembl:ENSMUSP00000103245|uniprotkb:P70421|uniprotkb:Q3U2D6|uniprotkb:Q3URS6|uniprotkb:Q78K30|uniprotkb:Q9R255 intact:EBI-911206|uniprotkb:Q6P5G1|uniprotkb:Q8BIN2|ensembl:ENSMUSP00000155307 psi-mi:klf4_mouse(display_long)|uniprotkb:Klf4(gene name)|psi-mi:Klf4(display_short)|uniprotkb:Ezf(gene name synonym)|uniprotkb:Gklf(gene name synonym)|uniprotkb:Zie(gene name synonym)|uniprotkb:Epithelial zinc finger protein EZF(gene name synonym)|uniprotkb:Gut-enriched krueppel-like factor(gene name synonym) psi-mi:ddx17_mouse(display_long)|uniprotkb:DEAD box protein 17(gene name synonym)|uniprotkb:Ddx17(gene name)|psi-mi:Ddx17(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Moon et al. (2018) imex:IM-28837|pubmed:29374155 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26900379|imex:IM-28837-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000107619(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001010"(RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010033"(response to organic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014740"(negative regulation of muscle hyperplasia)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030154"(cell differentiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031077"(post-embryonic camera-type eye development)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|ensembl:ENSMUSG00000003032(gene)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071409"(cellular response to cycloheximide)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0120222"(regulation of blastocyst development)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904998"(negative regulation of leukocyte adhesion to arterial endothelial cell)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:2WBS|rcsb pdb:2WBU|rcsb pdb:4M9E|rcsb pdb:5KE6|rcsb pdb:5KE7|rcsb pdb:5KE8|rcsb pdb:5KE9|rcsb pdb:5KEA|rcsb pdb:5KEB|go:"GO:0051973"(positive regulation of telomerase activity)|refseq:NP_034767.2|dip:DIP-59920N refseq:NP_001035277.1|refseq:NP_951061.1|refseq:NP_951062.1|ensembl:ENSMUSG00000055065(gene)|ensembl:ENSMUST00000229877(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006364"(rRNA processing)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:0061614"(miRNA transcription)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q501J6|reactome:R-MMU-3899300 - - - figure legend:f3a sf7e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2021/03/31 2021/03/31 rogid:g++XMPgXaBO9C3bV8RbenG3JTxQ10090 rogid:uGXMsVmy7MWcTaJPNlkof05dS8I10090 rigid:AnJ4awhSquwfq0ZXPeQAUNmwUhQ false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q60793 uniprotkb:Q61656 intact:EBI-3043905|ensembl:ENSMUSP00000103245|uniprotkb:P70421|uniprotkb:Q3U2D6|uniprotkb:Q3URS6|uniprotkb:Q78K30|uniprotkb:Q9R255 intact:EBI-643076|uniprotkb:E9Q105 psi-mi:klf4_mouse(display_long)|uniprotkb:Klf4(gene name)|psi-mi:Klf4(display_short)|uniprotkb:Ezf(gene name synonym)|uniprotkb:Gklf(gene name synonym)|uniprotkb:Zie(gene name synonym)|uniprotkb:Epithelial zinc finger protein EZF(gene name synonym)|uniprotkb:Gut-enriched krueppel-like factor(gene name synonym) psi-mi:ddx5_mouse(display_long)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:RNA helicase p68(gene name synonym)|uniprotkb:DEAD box RNA helicase DEAD1(gene name synonym)|uniprotkb:Ddx5(gene name)|psi-mi:Ddx5(display_short)|uniprotkb:Tnz2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Moon et al. (2018) imex:IM-28837|pubmed:29374155 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26900379|imex:IM-28837-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000107619(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001010"(RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010033"(response to organic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014740"(negative regulation of muscle hyperplasia)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030154"(cell differentiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031077"(post-embryonic camera-type eye development)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|ensembl:ENSMUSG00000003032(gene)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071409"(cellular response to cycloheximide)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0120222"(regulation of blastocyst development)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904998"(negative regulation of leukocyte adhesion to arterial endothelial cell)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:2WBS|rcsb pdb:2WBU|rcsb pdb:4M9E|rcsb pdb:5KE6|rcsb pdb:5KE7|rcsb pdb:5KE8|rcsb pdb:5KE9|rcsb pdb:5KEA|rcsb pdb:5KEB|go:"GO:0051973"(positive regulation of telomerase activity)|refseq:NP_034767.2|dip:DIP-59920N interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012587(P68HR)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-MMU-3899300|reactome:R-MMU-72163|reactome:R-MMU-9018519|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009299"(mRNA transcription)|go:"GO:0019899"(enzyme binding)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061614"(miRNA transcription)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|dip:DIP-32293N|mint:Q61656 - - - figure legend:f3a sf7e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2021/03/31 2021/03/31 rogid:g++XMPgXaBO9C3bV8RbenG3JTxQ10090 rogid:X5OQN/Gdq852njTrHnlDliAjrQY10090 rigid:AnJ4awhSquwfq0ZXPeQAUNmwUhQ false flag tag:n-n - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O95793 uniprotkb:Q60793 intact:EBI-358174|uniprotkb:Q6GTM4|uniprotkb:Q9H5B5|intact:EBI-366174|uniprotkb:Q9H5B4|uniprotkb:Q9Y3Q2|uniprotkb:A8K9Z4|ensembl:ENSP00000360922|uniprotkb:E1P5Y1|uniprotkb:E1P608|uniprotkb:Q5JW29 intact:EBI-3043905|ensembl:ENSMUSP00000103245|uniprotkb:P70421|uniprotkb:Q3U2D6|uniprotkb:Q3URS6|uniprotkb:Q78K30|uniprotkb:Q9R255 psi-mi:stau1_human(display_long)|uniprotkb:STAU1(gene name)|psi-mi:STAU1(display_short)|uniprotkb:STAU(gene name synonym) psi-mi:klf4_mouse(display_long)|uniprotkb:Klf4(gene name)|psi-mi:Klf4(display_short)|uniprotkb:Ezf(gene name synonym)|uniprotkb:Gklf(gene name synonym)|uniprotkb:Zie(gene name synonym)|uniprotkb:Epithelial zinc finger protein EZF(gene name synonym)|uniprotkb:Gut-enriched krueppel-like factor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Moon et al. (2018) imex:IM-28837|pubmed:29374155 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26900416|imex:IM-28837-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001309856.1|refseq:NP_001309858.1|refseq:NP_001309859.1|refseq:NP_001032405.1|refseq:NP_004593.2|refseq:NP_059346.2|refseq:NP_059347.2|refseq:NP_059348.2|refseq:NP_001306063.1|refseq:NP_001306064.1|ensembl:ENSG00000124214(gene)|ensembl:ENST00000371856(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|refseq:XP_005260584.1|go:"GO:0099010"(modification of postsynaptic structure)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR044475|mint:O95793|rcsb pdb:4DKK|rcsb pdb:6HTU|rcsb pdb:6SDW|rcsb pdb:6SDY ensembl:ENSMUST00000107619(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001010"(RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010033"(response to organic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014740"(negative regulation of muscle hyperplasia)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030154"(cell differentiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031077"(post-embryonic camera-type eye development)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|ensembl:ENSMUSG00000003032(gene)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071409"(cellular response to cycloheximide)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0120222"(regulation of blastocyst development)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904998"(negative regulation of leukocyte adhesion to arterial endothelial cell)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:2WBS|rcsb pdb:2WBU|rcsb pdb:4M9E|rcsb pdb:5KE6|rcsb pdb:5KE7|rcsb pdb:5KE8|rcsb pdb:5KE9|rcsb pdb:5KEA|rcsb pdb:5KEB|go:"GO:0051973"(positive regulation of telomerase activity)|refseq:NP_034767.2|dip:DIP-59920N - - - figure legend:f3e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2021/03/31 2021/03/31 rogid:uYjbWja/hG5M/3likHLe00Z2FgY9606 rogid:g++XMPgXaBO9C3bV8RbenG3JTxQ10090 rigid:HUr5ppGZonoqAL1ftfNY1Y6ny3Q false - flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O95793 uniprotkb:Q60793 intact:EBI-358174|uniprotkb:Q6GTM4|uniprotkb:Q9H5B5|intact:EBI-366174|uniprotkb:Q9H5B4|uniprotkb:Q9Y3Q2|uniprotkb:A8K9Z4|ensembl:ENSP00000360922|uniprotkb:E1P5Y1|uniprotkb:E1P608|uniprotkb:Q5JW29 intact:EBI-3043905|ensembl:ENSMUSP00000103245|uniprotkb:P70421|uniprotkb:Q3U2D6|uniprotkb:Q3URS6|uniprotkb:Q78K30|uniprotkb:Q9R255 psi-mi:stau1_human(display_long)|uniprotkb:STAU1(gene name)|psi-mi:STAU1(display_short)|uniprotkb:STAU(gene name synonym) psi-mi:klf4_mouse(display_long)|uniprotkb:Klf4(gene name)|psi-mi:Klf4(display_short)|uniprotkb:Ezf(gene name synonym)|uniprotkb:Gklf(gene name synonym)|uniprotkb:Zie(gene name synonym)|uniprotkb:Epithelial zinc finger protein EZF(gene name synonym)|uniprotkb:Gut-enriched krueppel-like factor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Moon et al. (2018) imex:IM-28837|pubmed:29374155 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26900426|imex:IM-28837-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001309856.1|refseq:NP_001309858.1|refseq:NP_001309859.1|refseq:NP_001032405.1|refseq:NP_004593.2|refseq:NP_059346.2|refseq:NP_059347.2|refseq:NP_059348.2|refseq:NP_001306063.1|refseq:NP_001306064.1|ensembl:ENSG00000124214(gene)|ensembl:ENST00000371856(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|refseq:XP_005260584.1|go:"GO:0099010"(modification of postsynaptic structure)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR044475|mint:O95793|rcsb pdb:4DKK|rcsb pdb:6HTU|rcsb pdb:6SDW|rcsb pdb:6SDY ensembl:ENSMUST00000107619(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001010"(RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010033"(response to organic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014740"(negative regulation of muscle hyperplasia)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030154"(cell differentiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031077"(post-embryonic camera-type eye development)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|ensembl:ENSMUSG00000003032(gene)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071409"(cellular response to cycloheximide)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0120222"(regulation of blastocyst development)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904998"(negative regulation of leukocyte adhesion to arterial endothelial cell)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:2WBS|rcsb pdb:2WBU|rcsb pdb:4M9E|rcsb pdb:5KE6|rcsb pdb:5KE7|rcsb pdb:5KE8|rcsb pdb:5KE9|rcsb pdb:5KEA|rcsb pdb:5KEB|go:"GO:0051973"(positive regulation of telomerase activity)|refseq:NP_034767.2|dip:DIP-59920N - - - figure legend:sf7f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2021/03/31 2021/04/27 rogid:uYjbWja/hG5M/3likHLe00Z2FgY9606 rogid:g++XMPgXaBO9C3bV8RbenG3JTxQ10090 rigid:HUr5ppGZonoqAL1ftfNY1Y6ny3Q false ha tag:c-c flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q60793 uniprotkb:O95793 intact:EBI-3043905|ensembl:ENSMUSP00000103245|uniprotkb:P70421|uniprotkb:Q3U2D6|uniprotkb:Q3URS6|uniprotkb:Q78K30|uniprotkb:Q9R255 intact:EBI-358174|uniprotkb:Q6GTM4|uniprotkb:Q9H5B5|intact:EBI-366174|uniprotkb:Q9H5B4|uniprotkb:Q9Y3Q2|uniprotkb:A8K9Z4|ensembl:ENSP00000360922|uniprotkb:E1P5Y1|uniprotkb:E1P608|uniprotkb:Q5JW29 psi-mi:klf4_mouse(display_long)|uniprotkb:Klf4(gene name)|psi-mi:Klf4(display_short)|uniprotkb:Ezf(gene name synonym)|uniprotkb:Gklf(gene name synonym)|uniprotkb:Zie(gene name synonym)|uniprotkb:Epithelial zinc finger protein EZF(gene name synonym)|uniprotkb:Gut-enriched krueppel-like factor(gene name synonym) psi-mi:stau1_human(display_long)|uniprotkb:STAU1(gene name)|psi-mi:STAU1(display_short)|uniprotkb:STAU(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Moon et al. (2018) imex:IM-28837|pubmed:29374155 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26900436|imex:IM-28837-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000107619(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001010"(RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010033"(response to organic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014740"(negative regulation of muscle hyperplasia)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030154"(cell differentiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031077"(post-embryonic camera-type eye development)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|ensembl:ENSMUSG00000003032(gene)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071409"(cellular response to cycloheximide)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0120222"(regulation of blastocyst development)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904998"(negative regulation of leukocyte adhesion to arterial endothelial cell)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:2WBS|rcsb pdb:2WBU|rcsb pdb:4M9E|rcsb pdb:5KE6|rcsb pdb:5KE7|rcsb pdb:5KE8|rcsb pdb:5KE9|rcsb pdb:5KEA|rcsb pdb:5KEB|go:"GO:0051973"(positive regulation of telomerase activity)|refseq:NP_034767.2|dip:DIP-59920N refseq:NP_001309856.1|refseq:NP_001309858.1|refseq:NP_001309859.1|refseq:NP_001032405.1|refseq:NP_004593.2|refseq:NP_059346.2|refseq:NP_059347.2|refseq:NP_059348.2|refseq:NP_001306063.1|refseq:NP_001306064.1|ensembl:ENSG00000124214(gene)|ensembl:ENST00000371856(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|refseq:XP_005260584.1|go:"GO:0099010"(modification of postsynaptic structure)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR044475|mint:O95793|rcsb pdb:4DKK|rcsb pdb:6HTU|rcsb pdb:6SDW|rcsb pdb:6SDY - - - figure legend:sf7g sf7h|comment:Interestingly, we found that Klf4–Stau1 interaction is independent of RNAs|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2021/03/31 2021/04/27 rogid:g++XMPgXaBO9C3bV8RbenG3JTxQ10090 rogid:uYjbWja/hG5M/3likHLe00Z2FgY9606 rigid:HUr5ppGZonoqAL1ftfNY1Y6ny3Q false flag tag:n-n ha tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O95793 uniprotkb:Q60793 intact:EBI-358174|uniprotkb:Q6GTM4|uniprotkb:Q9H5B5|intact:EBI-366174|uniprotkb:Q9H5B4|uniprotkb:Q9Y3Q2|uniprotkb:A8K9Z4|ensembl:ENSP00000360922|uniprotkb:E1P5Y1|uniprotkb:E1P608|uniprotkb:Q5JW29 intact:EBI-3043905|ensembl:ENSMUSP00000103245|uniprotkb:P70421|uniprotkb:Q3U2D6|uniprotkb:Q3URS6|uniprotkb:Q78K30|uniprotkb:Q9R255 psi-mi:stau1_human(display_long)|uniprotkb:STAU1(gene name)|psi-mi:STAU1(display_short)|uniprotkb:STAU(gene name synonym) psi-mi:klf4_mouse(display_long)|uniprotkb:Klf4(gene name)|psi-mi:Klf4(display_short)|uniprotkb:Ezf(gene name synonym)|uniprotkb:Gklf(gene name synonym)|uniprotkb:Zie(gene name synonym)|uniprotkb:Epithelial zinc finger protein EZF(gene name synonym)|uniprotkb:Gut-enriched krueppel-like factor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Moon et al. (2018) imex:IM-28837|pubmed:29374155 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26900457|imex:IM-28837-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001309856.1|refseq:NP_001309858.1|refseq:NP_001309859.1|refseq:NP_001032405.1|refseq:NP_004593.2|refseq:NP_059346.2|refseq:NP_059347.2|refseq:NP_059348.2|refseq:NP_001306063.1|refseq:NP_001306064.1|ensembl:ENSG00000124214(gene)|ensembl:ENST00000371856(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|refseq:XP_005260584.1|go:"GO:0099010"(modification of postsynaptic structure)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR044475|mint:O95793|rcsb pdb:4DKK|rcsb pdb:6HTU|rcsb pdb:6SDW|rcsb pdb:6SDY ensembl:ENSMUST00000107619(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001010"(RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010033"(response to organic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014740"(negative regulation of muscle hyperplasia)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030154"(cell differentiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031077"(post-embryonic camera-type eye development)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|ensembl:ENSMUSG00000003032(gene)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071409"(cellular response to cycloheximide)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0120222"(regulation of blastocyst development)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904998"(negative regulation of leukocyte adhesion to arterial endothelial cell)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:2WBS|rcsb pdb:2WBU|rcsb pdb:4M9E|rcsb pdb:5KE6|rcsb pdb:5KE7|rcsb pdb:5KE8|rcsb pdb:5KE9|rcsb pdb:5KEA|rcsb pdb:5KEB|go:"GO:0051973"(positive regulation of telomerase activity)|refseq:NP_034767.2|dip:DIP-59920N - - - figure legend:f3g|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2021/03/31 2021/04/27 rogid:uYjbWja/hG5M/3likHLe00Z2FgY9606 rogid:g++XMPgXaBO9C3bV8RbenG3JTxQ10090 rigid:HUr5ppGZonoqAL1ftfNY1Y6ny3Q false ha tag:c-c flag tag:n-n|necessary binding region:402-483 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O95793 uniprotkb:Q92841 intact:EBI-358174|uniprotkb:Q6GTM4|uniprotkb:Q9H5B5|intact:EBI-366174|uniprotkb:Q9H5B4|uniprotkb:Q9Y3Q2|uniprotkb:A8K9Z4|ensembl:ENSP00000360922|uniprotkb:E1P5Y1|uniprotkb:E1P608|uniprotkb:Q5JW29 intact:EBI-746012|uniprotkb:Q69YT1|uniprotkb:Q6ICD6|uniprotkb:H3BLZ8|uniprotkb:B1AHM0|ensembl:ENSP00000385536 psi-mi:stau1_human(display_long)|uniprotkb:STAU1(gene name)|psi-mi:STAU1(display_short)|uniprotkb:STAU(gene name synonym) psi-mi:ddx17_human(display_long)|uniprotkb:DEAD box protein 17(gene name synonym)|uniprotkb:RNA-dependent helicase p72(gene name synonym)|uniprotkb:DEAD box protein p72(gene name synonym)|uniprotkb:DDX17(gene name)|psi-mi:DDX17(display_short)|uniprotkb:DEAD box protein p82(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Moon et al. (2018) imex:IM-28837|pubmed:29374155 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26907685|imex:IM-28837-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001309856.1|refseq:NP_001309858.1|refseq:NP_001309859.1|refseq:NP_001032405.1|refseq:NP_004593.2|refseq:NP_059346.2|refseq:NP_059347.2|refseq:NP_059348.2|refseq:NP_001306063.1|refseq:NP_001306064.1|ensembl:ENSG00000124214(gene)|ensembl:ENST00000371856(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|refseq:XP_005260584.1|go:"GO:0099010"(modification of postsynaptic structure)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR044475|mint:O95793|rcsb pdb:4DKK|rcsb pdb:6HTU|rcsb pdb:6SDW|rcsb pdb:6SDY refseq:NP_006377.2|ensembl:ENSG00000100201(gene)|ensembl:ENST00000403230(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q92841|rcsb pdb:6UV0|rcsb pdb:6UV1|rcsb pdb:6UV2|rcsb pdb:6UV3|rcsb pdb:6UV4|reactome:R-HSA-3899300|dip:DIP-29843N - - - figure legend:sf11e|comment:This interaction was increased by Klf4 overexpression.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2021/03/31 2021/04/27 rogid:uYjbWja/hG5M/3likHLe00Z2FgY9606 rogid:3UhUuhRSZg/zlM7UPDKYCqNmUho9606 rigid:d97G9423NihGJdYtHNQyzBeGG/Q false ha tag:c-c - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O95793 uniprotkb:P17844 intact:EBI-358174|uniprotkb:Q6GTM4|uniprotkb:Q9H5B5|intact:EBI-366174|uniprotkb:Q9H5B4|uniprotkb:Q9Y3Q2|uniprotkb:A8K9Z4|ensembl:ENSP00000360922|uniprotkb:E1P5Y1|uniprotkb:E1P608|uniprotkb:Q5JW29 intact:EBI-351962|uniprotkb:O75681|uniprotkb:Q53Y61|uniprotkb:B4DLW8|uniprotkb:E7ETL9|uniprotkb:B5BU21|uniprotkb:D3DU32|ensembl:ENSP00000225792|ensembl:ENSP00000403085|ensembl:ENSP00000463168|ensembl:ENSP00000464337|ensembl:ENSP00000504794 psi-mi:stau1_human(display_long)|uniprotkb:STAU1(gene name)|psi-mi:STAU1(display_short)|uniprotkb:STAU(gene name synonym) psi-mi:ddx5_human(display_long)|uniprotkb:HLR1(gene name synonym)|uniprotkb:DDX5(gene name)|psi-mi:DDX5(display_short)|uniprotkb:HELR(gene name synonym)|uniprotkb:G17P1(gene name synonym)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:RNA helicase p68(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Moon et al. (2018) imex:IM-28837|pubmed:29374155 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26907685|imex:IM-28837-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001309856.1|refseq:NP_001309858.1|refseq:NP_001309859.1|refseq:NP_001032405.1|refseq:NP_004593.2|refseq:NP_059346.2|refseq:NP_059347.2|refseq:NP_059348.2|refseq:NP_001306063.1|refseq:NP_001306064.1|ensembl:ENSG00000124214(gene)|ensembl:ENST00000371856(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|refseq:XP_005260584.1|go:"GO:0099010"(modification of postsynaptic structure)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR044475|mint:O95793|rcsb pdb:4DKK|rcsb pdb:6HTU|rcsb pdb:6SDW|rcsb pdb:6SDY refseq:NP_004387.1|refseq:NP_001307524.1|refseq:NP_001307525.1|dip:DIP-29844N|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012587(P68HR)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P17844|rcsb pdb:3FE2|rcsb pdb:4A4D|reactome:R-HSA-3899300|reactome:R-HSA-72163|reactome:R-HSA-9018519|reactome:R-HSA-9682706|reactome:R-HSA-9694686|ensembl:ENST00000225792(transcript)|ensembl:ENST00000450599(transcript)|ensembl:ENST00000577922(transcript)|ensembl:ENST00000585111(transcript)|ensembl:ENST00000676785(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009299"(mRNA transcription)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061614"(miRNA transcription)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|ensembl:ENSG00000108654(gene) - - - figure legend:sf11e|comment:This interaction was increased by Klf4 overexpression.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2021/03/31 2021/04/27 rogid:uYjbWja/hG5M/3likHLe00Z2FgY9606 rogid:BlaILQg90jqkI5+DdA0k5YTCGOo9606 rigid:d97G9423NihGJdYtHNQyzBeGG/Q false ha tag:c-c - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O95793 uniprotkb:Q60793 intact:EBI-358174|uniprotkb:Q6GTM4|uniprotkb:Q9H5B5|intact:EBI-366174|uniprotkb:Q9H5B4|uniprotkb:Q9Y3Q2|uniprotkb:A8K9Z4|ensembl:ENSP00000360922|uniprotkb:E1P5Y1|uniprotkb:E1P608|uniprotkb:Q5JW29 intact:EBI-3043905|ensembl:ENSMUSP00000103245|uniprotkb:P70421|uniprotkb:Q3U2D6|uniprotkb:Q3URS6|uniprotkb:Q78K30|uniprotkb:Q9R255 psi-mi:stau1_human(display_long)|uniprotkb:STAU1(gene name)|psi-mi:STAU1(display_short)|uniprotkb:STAU(gene name synonym) psi-mi:klf4_mouse(display_long)|uniprotkb:Klf4(gene name)|psi-mi:Klf4(display_short)|uniprotkb:Ezf(gene name synonym)|uniprotkb:Gklf(gene name synonym)|uniprotkb:Zie(gene name synonym)|uniprotkb:Epithelial zinc finger protein EZF(gene name synonym)|uniprotkb:Gut-enriched krueppel-like factor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Moon et al. (2018) imex:IM-28837|pubmed:29374155 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26907685|imex:IM-28837-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001309856.1|refseq:NP_001309858.1|refseq:NP_001309859.1|refseq:NP_001032405.1|refseq:NP_004593.2|refseq:NP_059346.2|refseq:NP_059347.2|refseq:NP_059348.2|refseq:NP_001306063.1|refseq:NP_001306064.1|ensembl:ENSG00000124214(gene)|ensembl:ENST00000371856(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|refseq:XP_005260584.1|go:"GO:0099010"(modification of postsynaptic structure)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR044475|mint:O95793|rcsb pdb:4DKK|rcsb pdb:6HTU|rcsb pdb:6SDW|rcsb pdb:6SDY ensembl:ENSMUST00000107619(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001010"(RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010033"(response to organic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014740"(negative regulation of muscle hyperplasia)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030154"(cell differentiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031077"(post-embryonic camera-type eye development)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|ensembl:ENSMUSG00000003032(gene)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071409"(cellular response to cycloheximide)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0120222"(regulation of blastocyst development)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904998"(negative regulation of leukocyte adhesion to arterial endothelial cell)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:2WBS|rcsb pdb:2WBU|rcsb pdb:4M9E|rcsb pdb:5KE6|rcsb pdb:5KE7|rcsb pdb:5KE8|rcsb pdb:5KE9|rcsb pdb:5KEA|rcsb pdb:5KEB|go:"GO:0051973"(positive regulation of telomerase activity)|refseq:NP_034767.2|dip:DIP-59920N - - - figure legend:sf11e|comment:This interaction was increased by Klf4 overexpression.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2021/03/31 2021/04/27 rogid:uYjbWja/hG5M/3likHLe00Z2FgY9606 rogid:g++XMPgXaBO9C3bV8RbenG3JTxQ10090 rigid:d97G9423NihGJdYtHNQyzBeGG/Q false ha tag:c-c flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O95793 uniprotkb:Q92841 intact:EBI-358174|uniprotkb:Q6GTM4|uniprotkb:Q9H5B5|intact:EBI-366174|uniprotkb:Q9H5B4|uniprotkb:Q9Y3Q2|uniprotkb:A8K9Z4|ensembl:ENSP00000360922|uniprotkb:E1P5Y1|uniprotkb:E1P608|uniprotkb:Q5JW29 intact:EBI-746012|uniprotkb:Q69YT1|uniprotkb:Q6ICD6|uniprotkb:H3BLZ8|uniprotkb:B1AHM0|ensembl:ENSP00000385536 psi-mi:stau1_human(display_long)|uniprotkb:STAU1(gene name)|psi-mi:STAU1(display_short)|uniprotkb:STAU(gene name synonym) psi-mi:ddx17_human(display_long)|uniprotkb:DEAD box protein 17(gene name synonym)|uniprotkb:RNA-dependent helicase p72(gene name synonym)|uniprotkb:DEAD box protein p72(gene name synonym)|uniprotkb:DDX17(gene name)|psi-mi:DDX17(display_short)|uniprotkb:DEAD box protein p82(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Moon et al. (2018) imex:IM-28837|pubmed:29374155 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26947630|imex:IM-28837-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001309856.1|refseq:NP_001309858.1|refseq:NP_001309859.1|refseq:NP_001032405.1|refseq:NP_004593.2|refseq:NP_059346.2|refseq:NP_059347.2|refseq:NP_059348.2|refseq:NP_001306063.1|refseq:NP_001306064.1|ensembl:ENSG00000124214(gene)|ensembl:ENST00000371856(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|refseq:XP_005260584.1|go:"GO:0099010"(modification of postsynaptic structure)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR044475|mint:O95793|rcsb pdb:4DKK|rcsb pdb:6HTU|rcsb pdb:6SDW|rcsb pdb:6SDY refseq:NP_006377.2|ensembl:ENSG00000100201(gene)|ensembl:ENST00000403230(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q92841|rcsb pdb:6UV0|rcsb pdb:6UV1|rcsb pdb:6UV2|rcsb pdb:6UV3|rcsb pdb:6UV4|reactome:R-HSA-3899300|dip:DIP-29843N - - - figure legend:sf11e|comment:This interaction was increased by Klf4 overexpression.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2021/03/31 2021/04/27 rogid:uYjbWja/hG5M/3likHLe00Z2FgY9606 rogid:3UhUuhRSZg/zlM7UPDKYCqNmUho9606 rigid:SZJ1dFXG5enwxbRcqGu5BFXTYYE false ha tag:c-c - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O95793 uniprotkb:P17844 intact:EBI-358174|uniprotkb:Q6GTM4|uniprotkb:Q9H5B5|intact:EBI-366174|uniprotkb:Q9H5B4|uniprotkb:Q9Y3Q2|uniprotkb:A8K9Z4|ensembl:ENSP00000360922|uniprotkb:E1P5Y1|uniprotkb:E1P608|uniprotkb:Q5JW29 intact:EBI-351962|uniprotkb:O75681|uniprotkb:Q53Y61|uniprotkb:B4DLW8|uniprotkb:E7ETL9|uniprotkb:B5BU21|uniprotkb:D3DU32|ensembl:ENSP00000225792|ensembl:ENSP00000403085|ensembl:ENSP00000463168|ensembl:ENSP00000464337|ensembl:ENSP00000504794 psi-mi:stau1_human(display_long)|uniprotkb:STAU1(gene name)|psi-mi:STAU1(display_short)|uniprotkb:STAU(gene name synonym) psi-mi:ddx5_human(display_long)|uniprotkb:HLR1(gene name synonym)|uniprotkb:DDX5(gene name)|psi-mi:DDX5(display_short)|uniprotkb:HELR(gene name synonym)|uniprotkb:G17P1(gene name synonym)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:RNA helicase p68(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Moon et al. (2018) imex:IM-28837|pubmed:29374155 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26947630|imex:IM-28837-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001309856.1|refseq:NP_001309858.1|refseq:NP_001309859.1|refseq:NP_001032405.1|refseq:NP_004593.2|refseq:NP_059346.2|refseq:NP_059347.2|refseq:NP_059348.2|refseq:NP_001306063.1|refseq:NP_001306064.1|ensembl:ENSG00000124214(gene)|ensembl:ENST00000371856(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|refseq:XP_005260584.1|go:"GO:0099010"(modification of postsynaptic structure)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR044475|mint:O95793|rcsb pdb:4DKK|rcsb pdb:6HTU|rcsb pdb:6SDW|rcsb pdb:6SDY refseq:NP_004387.1|refseq:NP_001307524.1|refseq:NP_001307525.1|dip:DIP-29844N|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012587(P68HR)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P17844|rcsb pdb:3FE2|rcsb pdb:4A4D|reactome:R-HSA-3899300|reactome:R-HSA-72163|reactome:R-HSA-9018519|reactome:R-HSA-9682706|reactome:R-HSA-9694686|ensembl:ENST00000225792(transcript)|ensembl:ENST00000450599(transcript)|ensembl:ENST00000577922(transcript)|ensembl:ENST00000585111(transcript)|ensembl:ENST00000676785(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009299"(mRNA transcription)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061614"(miRNA transcription)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|ensembl:ENSG00000108654(gene) - - - figure legend:sf11e|comment:This interaction was increased by Klf4 overexpression.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2021/03/31 2021/04/27 rogid:uYjbWja/hG5M/3likHLe00Z2FgY9606 rogid:BlaILQg90jqkI5+DdA0k5YTCGOo9606 rigid:SZJ1dFXG5enwxbRcqGu5BFXTYYE false ha tag:c-c - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q60793 uniprotkb:Q9Z108 intact:EBI-3043905|ensembl:ENSMUSP00000103245|uniprotkb:P70421|uniprotkb:Q3U2D6|uniprotkb:Q3URS6|uniprotkb:Q78K30|uniprotkb:Q9R255 intact:EBI-8020609|intact:UNK-5561237|ensembl:ENSMUSP00000104859 psi-mi:klf4_mouse(display_long)|uniprotkb:Klf4(gene name)|psi-mi:Klf4(display_short)|uniprotkb:Ezf(gene name synonym)|uniprotkb:Gklf(gene name synonym)|uniprotkb:Zie(gene name synonym)|uniprotkb:Epithelial zinc finger protein EZF(gene name synonym)|uniprotkb:Gut-enriched krueppel-like factor(gene name synonym) psi-mi:stau1_mouse(display_long)|uniprotkb:Stau1(gene name)|psi-mi:Stau1(display_short)|uniprotkb:Stau(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moon et al. (2018) imex:IM-28837|pubmed:29374155 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26900453|imex:IM-28837-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000107619(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001010"(RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010033"(response to organic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014740"(negative regulation of muscle hyperplasia)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030154"(cell differentiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031077"(post-embryonic camera-type eye development)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|ensembl:ENSMUSG00000003032(gene)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071409"(cellular response to cycloheximide)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0120222"(regulation of blastocyst development)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904998"(negative regulation of leukocyte adhesion to arterial endothelial cell)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:2WBS|rcsb pdb:2WBU|rcsb pdb:4M9E|rcsb pdb:5KE6|rcsb pdb:5KE7|rcsb pdb:5KE8|rcsb pdb:5KE9|rcsb pdb:5KEA|rcsb pdb:5KEB|go:"GO:0051973"(positive regulation of telomerase activity)|refseq:NP_034767.2|dip:DIP-59920N refseq:NP_035620.1|ensembl:ENSMUSG00000039536(gene)|ensembl:ENSMUST00000109236(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030425"(dendrite)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099010"(modification of postsynaptic structure)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR044475|mint:Q9Z108 - - comment:mint|function:"Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site" figure legend:f3f|comment:Ddx5 and Ddx17 were detected at a low level|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2021/03/31 2021/04/12 rogid:g++XMPgXaBO9C3bV8RbenG3JTxQ10090 rogid:9zPJq1T9MxPD12EiZZWLuRcCpTk10090 rigid:AnJ4awhSquwfq0ZXPeQAUNmwUhQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q60793 uniprotkb:Q501J6 intact:EBI-3043905|ensembl:ENSMUSP00000103245|uniprotkb:P70421|uniprotkb:Q3U2D6|uniprotkb:Q3URS6|uniprotkb:Q78K30|uniprotkb:Q9R255 intact:EBI-911206|uniprotkb:Q6P5G1|uniprotkb:Q8BIN2|ensembl:ENSMUSP00000155307 psi-mi:klf4_mouse(display_long)|uniprotkb:Klf4(gene name)|psi-mi:Klf4(display_short)|uniprotkb:Ezf(gene name synonym)|uniprotkb:Gklf(gene name synonym)|uniprotkb:Zie(gene name synonym)|uniprotkb:Epithelial zinc finger protein EZF(gene name synonym)|uniprotkb:Gut-enriched krueppel-like factor(gene name synonym) psi-mi:ddx17_mouse(display_long)|uniprotkb:DEAD box protein 17(gene name synonym)|uniprotkb:Ddx17(gene name)|psi-mi:Ddx17(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moon et al. (2018) imex:IM-28837|pubmed:29374155 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26900453|imex:IM-28837-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000107619(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001010"(RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010033"(response to organic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014740"(negative regulation of muscle hyperplasia)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030154"(cell differentiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031077"(post-embryonic camera-type eye development)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|ensembl:ENSMUSG00000003032(gene)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071409"(cellular response to cycloheximide)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0120222"(regulation of blastocyst development)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904998"(negative regulation of leukocyte adhesion to arterial endothelial cell)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:2WBS|rcsb pdb:2WBU|rcsb pdb:4M9E|rcsb pdb:5KE6|rcsb pdb:5KE7|rcsb pdb:5KE8|rcsb pdb:5KE9|rcsb pdb:5KEA|rcsb pdb:5KEB|go:"GO:0051973"(positive regulation of telomerase activity)|refseq:NP_034767.2|dip:DIP-59920N refseq:NP_001035277.1|refseq:NP_951061.1|refseq:NP_951062.1|ensembl:ENSMUSG00000055065(gene)|ensembl:ENSMUST00000229877(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006364"(rRNA processing)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:0061614"(miRNA transcription)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q501J6|reactome:R-MMU-3899300 - - - figure legend:f3f|comment:Ddx5 and Ddx17 were detected at a low level|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2021/03/31 2021/04/12 rogid:g++XMPgXaBO9C3bV8RbenG3JTxQ10090 rogid:uGXMsVmy7MWcTaJPNlkof05dS8I10090 rigid:AnJ4awhSquwfq0ZXPeQAUNmwUhQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q60793 uniprotkb:Q61656 intact:EBI-3043905|ensembl:ENSMUSP00000103245|uniprotkb:P70421|uniprotkb:Q3U2D6|uniprotkb:Q3URS6|uniprotkb:Q78K30|uniprotkb:Q9R255 intact:EBI-643076|uniprotkb:E9Q105 psi-mi:klf4_mouse(display_long)|uniprotkb:Klf4(gene name)|psi-mi:Klf4(display_short)|uniprotkb:Ezf(gene name synonym)|uniprotkb:Gklf(gene name synonym)|uniprotkb:Zie(gene name synonym)|uniprotkb:Epithelial zinc finger protein EZF(gene name synonym)|uniprotkb:Gut-enriched krueppel-like factor(gene name synonym) psi-mi:ddx5_mouse(display_long)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:RNA helicase p68(gene name synonym)|uniprotkb:DEAD box RNA helicase DEAD1(gene name synonym)|uniprotkb:Ddx5(gene name)|psi-mi:Ddx5(display_short)|uniprotkb:Tnz2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moon et al. (2018) imex:IM-28837|pubmed:29374155 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-26900453|imex:IM-28837-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000107619(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001010"(RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010033"(response to organic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014740"(negative regulation of muscle hyperplasia)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030154"(cell differentiation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031077"(post-embryonic camera-type eye development)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|ensembl:ENSMUSG00000003032(gene)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071409"(cellular response to cycloheximide)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0120222"(regulation of blastocyst development)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904998"(negative regulation of leukocyte adhesion to arterial endothelial cell)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000342"("negative regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:2WBS|rcsb pdb:2WBU|rcsb pdb:4M9E|rcsb pdb:5KE6|rcsb pdb:5KE7|rcsb pdb:5KE8|rcsb pdb:5KE9|rcsb pdb:5KEA|rcsb pdb:5KEB|go:"GO:0051973"(positive regulation of telomerase activity)|refseq:NP_034767.2|dip:DIP-59920N interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012587(P68HR)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-MMU-3899300|reactome:R-MMU-72163|reactome:R-MMU-9018519|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009299"(mRNA transcription)|go:"GO:0019899"(enzyme binding)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061614"(miRNA transcription)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|dip:DIP-32293N|mint:Q61656 - - - figure legend:f3f|comment:Ddx5 and Ddx17 were detected at a low level|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse Neuronal precursor cells/neural stem progenitor cells) - 2021/03/31 2021/04/12 rogid:g++XMPgXaBO9C3bV8RbenG3JTxQ10090 rogid:X5OQN/Gdq852njTrHnlDliAjrQY10090 rigid:AnJ4awhSquwfq0ZXPeQAUNmwUhQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)