#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P37287 uniprotkb:P57054 intact:EBI-26643054|ensembl:ENSP00000442653|ensembl:ENSP00000369820|uniprotkb:B4E0V2|uniprotkb:Q16025|uniprotkb:Q16250 intact:EBI-17630288|uniprotkb:A0A0C4DH71|uniprotkb:B2RB18|uniprotkb:B2RE99|uniprotkb:B5BU92|uniprotkb:D3DSG7|uniprotkb:J3KR75|uniprotkb:Q53Y28|uniprotkb:Q96KI1|uniprotkb:Q9NZA6|ensembl:ENSP00000420037 psi-mi:piga_human(display_long)|uniprotkb:PIGA(gene name)|psi-mi:PIGA(display_short)|uniprotkb:GlcNAc-PI synthesis protein(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class A protein(gene name synonym) psi-mi:pigp_human(display_long)|uniprotkb:Down syndrome critical region protein 5(gene name synonym)|uniprotkb:Down syndrome critical region protein C(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class P protein(gene name synonym)|uniprotkb:NPD010(orf name)|uniprotkb:PIGP(gene name)|psi-mi:PIGP(display_short)|uniprotkb:DCRC(gene name synonym)|uniprotkb:DSCR5(gene name synonym)|uniprotkb:DSCRC(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Watanabe et al. (2000) imex:IM-28793|pubmed:10944123 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26871826|imex:IM-28793-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165195(gene)|ensembl:ENST00000333590(transcript)|ensembl:ENST00000542278(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008194"(UDP-glycosyltransferase activity)|go:"GO:0009893"(positive regulation of metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016254"(preassembly of GPI anchor in ER membrane)|go:"GO:0017176"(phosphatidylinositol N-acetylglucosaminyltransferase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001296(Glycosyl transferase, group 1)|interpro:IPR013234(PIGA, GPI anchor biosynthesis)|interpro:IPR039507|reactome:R-HSA-162710|refseq:NP_002632.1|refseq:NP_065206.3|refseq:XP_016885070.1 refseq:NP_001307409.1|refseq:NP_057514.2|refseq:NP_710148.1|refseq:NP_710149.1|refseq:XP_005261047.1|refseq:XP_011527898.1|refseq:XP_016883853.1|refseq:XP_016883854.1|ensembl:ENSG00000185808(gene)|ensembl:ENST00000464265(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017176"(phosphatidylinositol N-acetylglucosaminyltransferase activity)|interpro:IPR013717(PIG-P)|interpro:IPR016542(Phosphatidylinositol N-acetylglucosaminyltransferase, GPI19/PIG-P subunit)|reactome:R-HSA-162710 - - - figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-jy5)|taxid:9606(JY5 B-cell line) - 2021/03/05 2021/03/05 rogid:I6+5aCa/vOj/P/1aQ6Jg+Z9gbXk9606 rogid:vzbT7vpj//9+R0wfHcKjQL2Wc+w9606 rigid:8cm/n6jio/zt6RKJv8dCJFOr7+A false flag tag:n-n|glutathione s tranferase tag:n-n - - - psi-mi:"MI:0039"(edman degradation) psi-mi:"MI:0039"(edman degradation) uniprotkb:P37287 uniprotkb:O94777 intact:EBI-26643054|ensembl:ENSP00000442653|ensembl:ENSP00000369820|uniprotkb:B4E0V2|uniprotkb:Q16025|uniprotkb:Q16250 intact:EBI-9097061|uniprotkb:Q5XKK9|uniprotkb:Q6FGH3|ensembl:ENSP00000322181 psi-mi:piga_human(display_long)|uniprotkb:PIGA(gene name)|psi-mi:PIGA(display_short)|uniprotkb:GlcNAc-PI synthesis protein(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class A protein(gene name synonym) psi-mi:dpm2_human(display_long)|uniprotkb:DPM2(gene name)|psi-mi:DPM2(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 2(gene name synonym)|uniprotkb:My026(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Watanabe et al. (2000) imex:IM-28793|pubmed:10944123 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26871826|imex:IM-28793-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165195(gene)|ensembl:ENST00000333590(transcript)|ensembl:ENST00000542278(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008194"(UDP-glycosyltransferase activity)|go:"GO:0009893"(positive regulation of metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016254"(preassembly of GPI anchor in ER membrane)|go:"GO:0017176"(phosphatidylinositol N-acetylglucosaminyltransferase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001296(Glycosyl transferase, group 1)|interpro:IPR013234(PIGA, GPI anchor biosynthesis)|interpro:IPR039507|reactome:R-HSA-162710|refseq:NP_002632.1|refseq:NP_065206.3|refseq:XP_016885070.1 refseq:NP_003854.1|ensembl:ENSG00000136908(gene)|ensembl:ENST00000314392(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0019348"(dolichol metabolic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035269"(protein O-linked mannosylation)|interpro:IPR009914(Dolichol phosphate-mannose biosynthesis regulatory)|reactome:R-HSA-162699|reactome:R-HSA-162710|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377 - - - figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-jy5)|taxid:9606(JY5 B-cell line) - 2021/03/05 2021/03/05 rogid:I6+5aCa/vOj/P/1aQ6Jg+Z9gbXk9606 rogid:b1kR+UX6Sfr1TcOpQ0D4M3+xy8M9606 rigid:8cm/n6jio/zt6RKJv8dCJFOr7+A false flag tag:n-n|glutathione s tranferase tag:n-n - - - psi-mi:"MI:0039"(edman degradation) psi-mi:"MI:0039"(edman degradation) uniprotkb:P37287 uniprotkb:Q9BRB3 intact:EBI-26643054|ensembl:ENSP00000442653|ensembl:ENSP00000369820|uniprotkb:B4E0V2|uniprotkb:Q16025|uniprotkb:Q16250 intact:EBI-2339260|uniprotkb:O14927|uniprotkb:A2IDE1|uniprotkb:Q96G00|uniprotkb:Q9UJH4|uniprotkb:Q96S22|uniprotkb:D3DU52|intact:EBI-28972732|ensembl:ENSP00000026218 psi-mi:piga_human(display_long)|uniprotkb:PIGA(gene name)|psi-mi:PIGA(display_short)|uniprotkb:GlcNAc-PI synthesis protein(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class A protein(gene name synonym) psi-mi:pigq_human(display_long)|uniprotkb:PIGQ(gene name)|psi-mi:PIGQ(display_short)|uniprotkb:GPI1(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class Q protein(gene name synonym)|uniprotkb:N-acetylglucosamyl transferase component GPI1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Watanabe et al. (2000) imex:IM-28793|pubmed:10944123 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26871826|imex:IM-28793-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165195(gene)|ensembl:ENST00000333590(transcript)|ensembl:ENST00000542278(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008194"(UDP-glycosyltransferase activity)|go:"GO:0009893"(positive regulation of metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016254"(preassembly of GPI anchor in ER membrane)|go:"GO:0017176"(phosphatidylinositol N-acetylglucosaminyltransferase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001296(Glycosyl transferase, group 1)|interpro:IPR013234(PIGA, GPI anchor biosynthesis)|interpro:IPR039507|reactome:R-HSA-162710|refseq:NP_002632.1|refseq:NP_065206.3|refseq:XP_016885070.1 ensembl:ENSP00000026218|ensembl:ENST00000321878|ensembl:ENSP00000326674|ensembl:ENST00000409527|ensembl:ENSP00000386760|ensembl:ENST00000470411|ensembl:ENSP00000439650|refseq:NP_004195.2|refseq:NP_683721.1|ensembl:ENSG00000007541(gene)|ensembl:ENST00000026218(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017176"(phosphatidylinositol N-acetylglucosaminyltransferase activity)|interpro:IPR007720(N-acetylglucosaminyl transferase component)|reactome:R-HSA-162710 - - - figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-jy5)|taxid:9606(JY5 B-cell line) - 2021/03/05 2021/03/05 rogid:I6+5aCa/vOj/P/1aQ6Jg+Z9gbXk9606 rogid:nL4mUBYkxZwFJqjKwdm7qAZU8NI9606 rigid:8cm/n6jio/zt6RKJv8dCJFOr7+A false flag tag:n-n|glutathione s tranferase tag:n-n - - - psi-mi:"MI:0039"(edman degradation) psi-mi:"MI:0039"(edman degradation) uniprotkb:P37287 uniprotkb:Q14442 intact:EBI-26643054|ensembl:ENSP00000442653|ensembl:ENSP00000369820|uniprotkb:B4E0V2|uniprotkb:Q16025|uniprotkb:Q16250 intact:EBI-2803676|uniprotkb:B2RAA4|ensembl:ENSP00000216452 psi-mi:piga_human(display_long)|uniprotkb:PIGA(gene name)|psi-mi:PIGA(display_short)|uniprotkb:GlcNAc-PI synthesis protein(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class A protein(gene name synonym) psi-mi:pigh_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class H protein(gene name synonym)|uniprotkb:PIGH(gene name)|psi-mi:PIGH(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Watanabe et al. (2000) imex:IM-28793|pubmed:10944123 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26871826|imex:IM-28793-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165195(gene)|ensembl:ENST00000333590(transcript)|ensembl:ENST00000542278(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008194"(UDP-glycosyltransferase activity)|go:"GO:0009893"(positive regulation of metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016254"(preassembly of GPI anchor in ER membrane)|go:"GO:0017176"(phosphatidylinositol N-acetylglucosaminyltransferase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001296(Glycosyl transferase, group 1)|interpro:IPR013234(PIGA, GPI anchor biosynthesis)|interpro:IPR039507|reactome:R-HSA-162710|refseq:NP_002632.1|refseq:NP_065206.3|refseq:XP_016885070.1 ensembl:ENSG00000100564(gene)|ensembl:ENST00000216452(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0003824"(catalytic activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0017176"(phosphatidylinositol N-acetylglucosaminyltransferase activity)|interpro:IPR019328|interpro:IPR044215|mint:Q14442|reactome:R-HSA-162710|go:"GO:0006506"(GPI anchor biosynthetic process)|refseq:NP_004560.1 - - - figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-jy5)|taxid:9606(JY5 B-cell line) - 2021/03/05 2021/03/05 rogid:I6+5aCa/vOj/P/1aQ6Jg+Z9gbXk9606 rogid:wCS89Qt+gANFwAjAEFGvsQhXsqU9606 rigid:8cm/n6jio/zt6RKJv8dCJFOr7+A false flag tag:n-n|glutathione s tranferase tag:n-n - - - psi-mi:"MI:0039"(edman degradation) psi-mi:"MI:0039"(edman degradation) uniprotkb:P37287 uniprotkb:Q92535 intact:EBI-26643054|ensembl:ENSP00000442653|ensembl:ENSP00000369820|uniprotkb:B4E0V2|uniprotkb:Q16025|uniprotkb:Q16250 intact:EBI-721918|uniprotkb:O14491|ensembl:ENSP00000356701|ensembl:ENSP00000356702 psi-mi:piga_human(display_long)|uniprotkb:PIGA(gene name)|psi-mi:PIGA(display_short)|uniprotkb:GlcNAc-PI synthesis protein(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class A protein(gene name synonym) psi-mi:pigc_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class C protein(gene name synonym)|uniprotkb:PIGC(gene name)|psi-mi:PIGC(display_short)|uniprotkb:GPI2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Watanabe et al. (2000) imex:IM-28793|pubmed:10944123 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26871826|imex:IM-28793-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000165195(gene)|ensembl:ENST00000333590(transcript)|ensembl:ENST00000542278(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008194"(UDP-glycosyltransferase activity)|go:"GO:0009893"(positive regulation of metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016254"(preassembly of GPI anchor in ER membrane)|go:"GO:0017176"(phosphatidylinositol N-acetylglucosaminyltransferase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001296(Glycosyl transferase, group 1)|interpro:IPR013234(PIGA, GPI anchor biosynthesis)|interpro:IPR039507|reactome:R-HSA-162710|refseq:NP_002632.1|refseq:NP_065206.3|refseq:XP_016885070.1 ensembl:ENSG00000135845(gene)|ensembl:ENST00000344529(transcript)|ensembl:ENST00000367728(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0003824"(catalytic activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR009450(Phosphatidylinositol N-acetylglucosaminyltransferase)|reactome:R-HSA-162710|refseq:NP_002633.1|refseq:NP_714969.1 - - - figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-jy5)|taxid:9606(JY5 B-cell line) - 2021/03/05 2021/03/05 rogid:I6+5aCa/vOj/P/1aQ6Jg+Z9gbXk9606 rogid:ei/cjqRAkgPWw+lZXNwZnF31C0I9606 rigid:8cm/n6jio/zt6RKJv8dCJFOr7+A false flag tag:n-n|glutathione s tranferase tag:n-n - - - psi-mi:"MI:0039"(edman degradation) psi-mi:"MI:0039"(edman degradation) uniprotkb:P57054 uniprotkb:P37287 intact:EBI-17630288|uniprotkb:A0A0C4DH71|uniprotkb:B2RB18|uniprotkb:B2RE99|uniprotkb:B5BU92|uniprotkb:D3DSG7|uniprotkb:J3KR75|uniprotkb:Q53Y28|uniprotkb:Q96KI1|uniprotkb:Q9NZA6|ensembl:ENSP00000420037 intact:EBI-26643054|ensembl:ENSP00000442653|ensembl:ENSP00000369820|uniprotkb:B4E0V2|uniprotkb:Q16025|uniprotkb:Q16250 psi-mi:pigp_human(display_long)|uniprotkb:Down syndrome critical region protein 5(gene name synonym)|uniprotkb:Down syndrome critical region protein C(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class P protein(gene name synonym)|uniprotkb:NPD010(orf name)|uniprotkb:PIGP(gene name)|psi-mi:PIGP(display_short)|uniprotkb:DCRC(gene name synonym)|uniprotkb:DSCR5(gene name synonym)|uniprotkb:DSCRC(gene name synonym) psi-mi:piga_human(display_long)|uniprotkb:PIGA(gene name)|psi-mi:PIGA(display_short)|uniprotkb:GlcNAc-PI synthesis protein(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class A protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Watanabe et al. (2000) imex:IM-28793|pubmed:10944123 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26871838|imex:IM-28793-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001307409.1|refseq:NP_057514.2|refseq:NP_710148.1|refseq:NP_710149.1|refseq:XP_005261047.1|refseq:XP_011527898.1|refseq:XP_016883853.1|refseq:XP_016883854.1|ensembl:ENSG00000185808(gene)|ensembl:ENST00000464265(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017176"(phosphatidylinositol N-acetylglucosaminyltransferase activity)|interpro:IPR013717(PIG-P)|interpro:IPR016542(Phosphatidylinositol N-acetylglucosaminyltransferase, GPI19/PIG-P subunit)|reactome:R-HSA-162710 ensembl:ENSG00000165195(gene)|ensembl:ENST00000333590(transcript)|ensembl:ENST00000542278(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008194"(UDP-glycosyltransferase activity)|go:"GO:0009893"(positive regulation of metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016254"(preassembly of GPI anchor in ER membrane)|go:"GO:0017176"(phosphatidylinositol N-acetylglucosaminyltransferase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001296(Glycosyl transferase, group 1)|interpro:IPR013234(PIGA, GPI anchor biosynthesis)|interpro:IPR039507|reactome:R-HSA-162710|refseq:NP_002632.1|refseq:NP_065206.3|refseq:XP_016885070.1 - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-jy5)|taxid:9606(JY5 B-cell line) - 2021/03/05 2021/03/05 rogid:vzbT7vpj//9+R0wfHcKjQL2Wc+w9606 rogid:I6+5aCa/vOj/P/1aQ6Jg+Z9gbXk9606 rigid:CPRjQc4JVmX7w3k1VthX2CiggUk false flag tag:n-n glutathione s tranferase tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P57054 uniprotkb:Q9BRB3 intact:EBI-17630288|uniprotkb:A0A0C4DH71|uniprotkb:B2RB18|uniprotkb:B2RE99|uniprotkb:B5BU92|uniprotkb:D3DSG7|uniprotkb:J3KR75|uniprotkb:Q53Y28|uniprotkb:Q96KI1|uniprotkb:Q9NZA6|ensembl:ENSP00000420037 intact:EBI-2339260|uniprotkb:O14927|uniprotkb:A2IDE1|uniprotkb:Q96G00|uniprotkb:Q9UJH4|uniprotkb:Q96S22|uniprotkb:D3DU52|intact:EBI-28972732|ensembl:ENSP00000026218 psi-mi:pigp_human(display_long)|uniprotkb:Down syndrome critical region protein 5(gene name synonym)|uniprotkb:Down syndrome critical region protein C(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class P protein(gene name synonym)|uniprotkb:NPD010(orf name)|uniprotkb:PIGP(gene name)|psi-mi:PIGP(display_short)|uniprotkb:DCRC(gene name synonym)|uniprotkb:DSCR5(gene name synonym)|uniprotkb:DSCRC(gene name synonym) psi-mi:pigq_human(display_long)|uniprotkb:PIGQ(gene name)|psi-mi:PIGQ(display_short)|uniprotkb:GPI1(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class Q protein(gene name synonym)|uniprotkb:N-acetylglucosamyl transferase component GPI1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Watanabe et al. (2000) imex:IM-28793|pubmed:10944123 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26871852|imex:IM-28793-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001307409.1|refseq:NP_057514.2|refseq:NP_710148.1|refseq:NP_710149.1|refseq:XP_005261047.1|refseq:XP_011527898.1|refseq:XP_016883853.1|refseq:XP_016883854.1|ensembl:ENSG00000185808(gene)|ensembl:ENST00000464265(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017176"(phosphatidylinositol N-acetylglucosaminyltransferase activity)|interpro:IPR013717(PIG-P)|interpro:IPR016542(Phosphatidylinositol N-acetylglucosaminyltransferase, GPI19/PIG-P subunit)|reactome:R-HSA-162710 ensembl:ENSP00000026218|ensembl:ENST00000321878|ensembl:ENSP00000326674|ensembl:ENST00000409527|ensembl:ENSP00000386760|ensembl:ENST00000470411|ensembl:ENSP00000439650|refseq:NP_004195.2|refseq:NP_683721.1|ensembl:ENSG00000007541(gene)|ensembl:ENST00000026218(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017176"(phosphatidylinositol N-acetylglucosaminyltransferase activity)|interpro:IPR007720(N-acetylglucosaminyl transferase component)|reactome:R-HSA-162710 - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-jy5)|taxid:9606(JY5 B-cell line) - 2021/03/05 2021/03/05 rogid:vzbT7vpj//9+R0wfHcKjQL2Wc+w9606 rogid:nL4mUBYkxZwFJqjKwdm7qAZU8NI9606 rigid:6ETHheKhHYU/92hbKZXa508u6QM false flag tag:n-n glutathione s tranferase tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O94777 uniprotkb:Q9BRB3 intact:EBI-9097061|uniprotkb:Q5XKK9|uniprotkb:Q6FGH3|ensembl:ENSP00000322181 intact:EBI-2339260|uniprotkb:O14927|uniprotkb:A2IDE1|uniprotkb:Q96G00|uniprotkb:Q9UJH4|uniprotkb:Q96S22|uniprotkb:D3DU52|intact:EBI-28972732|ensembl:ENSP00000026218 psi-mi:dpm2_human(display_long)|uniprotkb:DPM2(gene name)|psi-mi:DPM2(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 2(gene name synonym)|uniprotkb:My026(orf name) psi-mi:pigq_human(display_long)|uniprotkb:PIGQ(gene name)|psi-mi:PIGQ(display_short)|uniprotkb:GPI1(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class Q protein(gene name synonym)|uniprotkb:N-acetylglucosamyl transferase component GPI1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Watanabe et al. (2000) imex:IM-28793|pubmed:10944123 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26871988|imex:IM-28793-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003854.1|ensembl:ENSG00000136908(gene)|ensembl:ENST00000314392(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0019348"(dolichol metabolic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035269"(protein O-linked mannosylation)|interpro:IPR009914(Dolichol phosphate-mannose biosynthesis regulatory)|reactome:R-HSA-162699|reactome:R-HSA-162710|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377 ensembl:ENSP00000026218|ensembl:ENST00000321878|ensembl:ENSP00000326674|ensembl:ENST00000409527|ensembl:ENSP00000386760|ensembl:ENST00000470411|ensembl:ENSP00000439650|refseq:NP_004195.2|refseq:NP_683721.1|ensembl:ENSG00000007541(gene)|ensembl:ENST00000026218(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017176"(phosphatidylinositol N-acetylglucosaminyltransferase activity)|interpro:IPR007720(N-acetylglucosaminyl transferase component)|reactome:R-HSA-162710 - - - figure legend:Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-jy5)|taxid:9606(JY5 B-cell line) - 2021/03/05 2021/03/05 rogid:b1kR+UX6Sfr1TcOpQ0D4M3+xy8M9606 rogid:nL4mUBYkxZwFJqjKwdm7qAZU8NI9606 rigid:9eIfftOHLtOMjBIknhWvLcUuZsk false glutathione s tranferase tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O94777 uniprotkb:P37287 intact:EBI-9097061|uniprotkb:Q5XKK9|uniprotkb:Q6FGH3|ensembl:ENSP00000322181 intact:EBI-26643054|ensembl:ENSP00000442653|ensembl:ENSP00000369820|uniprotkb:B4E0V2|uniprotkb:Q16025|uniprotkb:Q16250 psi-mi:dpm2_human(display_long)|uniprotkb:DPM2(gene name)|psi-mi:DPM2(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 2(gene name synonym)|uniprotkb:My026(orf name) psi-mi:piga_human(display_long)|uniprotkb:PIGA(gene name)|psi-mi:PIGA(display_short)|uniprotkb:GlcNAc-PI synthesis protein(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class A protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Watanabe et al. (2000) imex:IM-28793|pubmed:10944123 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26871996|imex:IM-28793-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003854.1|ensembl:ENSG00000136908(gene)|ensembl:ENST00000314392(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0019348"(dolichol metabolic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035269"(protein O-linked mannosylation)|interpro:IPR009914(Dolichol phosphate-mannose biosynthesis regulatory)|reactome:R-HSA-162699|reactome:R-HSA-162710|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377 ensembl:ENSG00000165195(gene)|ensembl:ENST00000333590(transcript)|ensembl:ENST00000542278(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008194"(UDP-glycosyltransferase activity)|go:"GO:0009893"(positive regulation of metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016254"(preassembly of GPI anchor in ER membrane)|go:"GO:0017176"(phosphatidylinositol N-acetylglucosaminyltransferase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001296(Glycosyl transferase, group 1)|interpro:IPR013234(PIGA, GPI anchor biosynthesis)|interpro:IPR039507|reactome:R-HSA-162710|refseq:NP_002632.1|refseq:NP_065206.3|refseq:XP_016885070.1 - - - figure legend:Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-jy5)|taxid:9606(JY5 B-cell line) - 2021/03/05 2021/03/05 rogid:b1kR+UX6Sfr1TcOpQ0D4M3+xy8M9606 rogid:I6+5aCa/vOj/P/1aQ6Jg+Z9gbXk9606 rigid:uzkbetpSkWu+1ignOKyIXqpF0qw false glutathione s tranferase tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O94777 uniprotkb:Q92535 intact:EBI-9097061|uniprotkb:Q5XKK9|uniprotkb:Q6FGH3|ensembl:ENSP00000322181 intact:EBI-721918|uniprotkb:O14491|ensembl:ENSP00000356701|ensembl:ENSP00000356702 psi-mi:dpm2_human(display_long)|uniprotkb:DPM2(gene name)|psi-mi:DPM2(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 2(gene name synonym)|uniprotkb:My026(orf name) psi-mi:pigc_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class C protein(gene name synonym)|uniprotkb:PIGC(gene name)|psi-mi:PIGC(display_short)|uniprotkb:GPI2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Watanabe et al. (2000) imex:IM-28793|pubmed:10944123 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26872004|imex:IM-28793-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003854.1|ensembl:ENSG00000136908(gene)|ensembl:ENST00000314392(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0019348"(dolichol metabolic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035269"(protein O-linked mannosylation)|interpro:IPR009914(Dolichol phosphate-mannose biosynthesis regulatory)|reactome:R-HSA-162699|reactome:R-HSA-162710|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377 ensembl:ENSG00000135845(gene)|ensembl:ENST00000344529(transcript)|ensembl:ENST00000367728(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0003824"(catalytic activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR009450(Phosphatidylinositol N-acetylglucosaminyltransferase)|reactome:R-HSA-162710|refseq:NP_002633.1|refseq:NP_714969.1 - - - figure legend:Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-jy5)|taxid:9606(JY5 B-cell line) - 2021/03/05 2021/03/05 rogid:b1kR+UX6Sfr1TcOpQ0D4M3+xy8M9606 rogid:ei/cjqRAkgPWw+lZXNwZnF31C0I9606 rigid:OssW8BW6G0FxKukFUDzcUnHogA0 false glutathione s tranferase tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O94777 uniprotkb:Q9P2X0 intact:EBI-9097061|uniprotkb:Q5XKK9|uniprotkb:Q6FGH3|ensembl:ENSP00000322181 intact:EBI-9087337|uniprotkb:Q5SR62|uniprotkb:Q5SR63|uniprotkb:Q9BXN4|uniprotkb:Q9BXN5|ensembl:ENSP00000344338|ensembl:ENSP00000357385 psi-mi:dpm2_human(display_long)|uniprotkb:DPM2(gene name)|psi-mi:DPM2(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 2(gene name synonym)|uniprotkb:My026(orf name) psi-mi:dpm3_human(display_long)|uniprotkb:DPM3(gene name)|psi-mi:DPM3(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 3(gene name synonym)|uniprotkb:Dolichyl-phosphate beta-D-mannosyltransferase subunit 3(gene name synonym)|uniprotkb:Mannose-P-dolichol synthase subunit 3(gene name synonym)|uniprotkb:Prostin-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Watanabe et al. (2000) imex:IM-28793|pubmed:10944123 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26872012|imex:IM-28793-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003854.1|ensembl:ENSG00000136908(gene)|ensembl:ENST00000314392(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0019348"(dolichol metabolic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035269"(protein O-linked mannosylation)|interpro:IPR009914(Dolichol phosphate-mannose biosynthesis regulatory)|reactome:R-HSA-162699|reactome:R-HSA-162710|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377 refseq:XP_016856987.1|refseq:NP_061846.2|refseq:NP_714963.1|ensembl:ENSG00000179085(gene)|ensembl:ENST00000341298(transcript)|ensembl:ENST00000368400(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0018406"(protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031501"(mannosyltransferase complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035268"(protein mannosylation)|go:"GO:0035269"(protein O-linked mannosylation)|interpro:IPR013174(Dolichol-phosphate mannosyltransferase subunit 3)|reactome:R-HSA-162699|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377 - - - figure legend:Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-jy5)|taxid:9606(JY5 B-cell line) - 2021/03/05 2021/03/05 rogid:b1kR+UX6Sfr1TcOpQ0D4M3+xy8M9606 rogid:0wf0wox4cCMWDiy9qDpf2l7NTps9606 rigid:7s8qdN9+gzcyHMg6Sq3bM6pEZgI false glutathione s tranferase tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O94777 uniprotkb:P57054 intact:EBI-9097061|uniprotkb:Q5XKK9|uniprotkb:Q6FGH3|ensembl:ENSP00000322181 intact:EBI-17630288|uniprotkb:A0A0C4DH71|uniprotkb:B2RB18|uniprotkb:B2RE99|uniprotkb:B5BU92|uniprotkb:D3DSG7|uniprotkb:J3KR75|uniprotkb:Q53Y28|uniprotkb:Q96KI1|uniprotkb:Q9NZA6|ensembl:ENSP00000420037 psi-mi:dpm2_human(display_long)|uniprotkb:DPM2(gene name)|psi-mi:DPM2(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 2(gene name synonym)|uniprotkb:My026(orf name) psi-mi:pigp_human(display_long)|uniprotkb:Down syndrome critical region protein 5(gene name synonym)|uniprotkb:Down syndrome critical region protein C(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class P protein(gene name synonym)|uniprotkb:NPD010(orf name)|uniprotkb:PIGP(gene name)|psi-mi:PIGP(display_short)|uniprotkb:DCRC(gene name synonym)|uniprotkb:DSCR5(gene name synonym)|uniprotkb:DSCRC(gene name synonym) psi-mi:"MI:0096"(pull down) Watanabe et al. (2000) imex:IM-28793|pubmed:10944123 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26871885|imex:IM-28793-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003854.1|ensembl:ENSG00000136908(gene)|ensembl:ENST00000314392(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0019348"(dolichol metabolic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035269"(protein O-linked mannosylation)|interpro:IPR009914(Dolichol phosphate-mannose biosynthesis regulatory)|reactome:R-HSA-162699|reactome:R-HSA-162710|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377 refseq:NP_001307409.1|refseq:NP_057514.2|refseq:NP_710148.1|refseq:NP_710149.1|refseq:XP_005261047.1|refseq:XP_011527898.1|refseq:XP_016883853.1|refseq:XP_016883854.1|ensembl:ENSG00000185808(gene)|ensembl:ENST00000464265(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017176"(phosphatidylinositol N-acetylglucosaminyltransferase activity)|interpro:IPR013717(PIG-P)|interpro:IPR016542(Phosphatidylinositol N-acetylglucosaminyltransferase, GPI19/PIG-P subunit)|reactome:R-HSA-162710 - - - figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-jy5)|taxid:9606(JY5 B-cell line) - 2021/03/05 2021/03/05 rogid:b1kR+UX6Sfr1TcOpQ0D4M3+xy8M9606 rogid:vzbT7vpj//9+R0wfHcKjQL2Wc+w9606 rigid:8cm/n6jio/zt6RKJv8dCJFOr7+A false glutathione s tranferase tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0815"(confirmation by molecular weight)|psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O94777 uniprotkb:Q14442 intact:EBI-9097061|uniprotkb:Q5XKK9|uniprotkb:Q6FGH3|ensembl:ENSP00000322181 intact:EBI-2803676|uniprotkb:B2RAA4|ensembl:ENSP00000216452 psi-mi:dpm2_human(display_long)|uniprotkb:DPM2(gene name)|psi-mi:DPM2(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 2(gene name synonym)|uniprotkb:My026(orf name) psi-mi:pigh_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class H protein(gene name synonym)|uniprotkb:PIGH(gene name)|psi-mi:PIGH(display_short) psi-mi:"MI:0096"(pull down) Watanabe et al. (2000) imex:IM-28793|pubmed:10944123 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26871885|imex:IM-28793-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003854.1|ensembl:ENSG00000136908(gene)|ensembl:ENST00000314392(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0019348"(dolichol metabolic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035269"(protein O-linked mannosylation)|interpro:IPR009914(Dolichol phosphate-mannose biosynthesis regulatory)|reactome:R-HSA-162699|reactome:R-HSA-162710|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377 ensembl:ENSG00000100564(gene)|ensembl:ENST00000216452(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0003824"(catalytic activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0017176"(phosphatidylinositol N-acetylglucosaminyltransferase activity)|interpro:IPR019328|interpro:IPR044215|mint:Q14442|reactome:R-HSA-162710|go:"GO:0006506"(GPI anchor biosynthetic process)|refseq:NP_004560.1 - - - figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-jy5)|taxid:9606(JY5 B-cell line) - 2021/03/05 2021/03/05 rogid:b1kR+UX6Sfr1TcOpQ0D4M3+xy8M9606 rogid:wCS89Qt+gANFwAjAEFGvsQhXsqU9606 rigid:8cm/n6jio/zt6RKJv8dCJFOr7+A false glutathione s tranferase tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0815"(confirmation by molecular weight)|psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O94777 uniprotkb:Q92535 intact:EBI-9097061|uniprotkb:Q5XKK9|uniprotkb:Q6FGH3|ensembl:ENSP00000322181 intact:EBI-721918|uniprotkb:O14491|ensembl:ENSP00000356701|ensembl:ENSP00000356702 psi-mi:dpm2_human(display_long)|uniprotkb:DPM2(gene name)|psi-mi:DPM2(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 2(gene name synonym)|uniprotkb:My026(orf name) psi-mi:pigc_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class C protein(gene name synonym)|uniprotkb:PIGC(gene name)|psi-mi:PIGC(display_short)|uniprotkb:GPI2(gene name synonym) psi-mi:"MI:0096"(pull down) Watanabe et al. (2000) imex:IM-28793|pubmed:10944123 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26871885|imex:IM-28793-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003854.1|ensembl:ENSG00000136908(gene)|ensembl:ENST00000314392(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0019348"(dolichol metabolic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035269"(protein O-linked mannosylation)|interpro:IPR009914(Dolichol phosphate-mannose biosynthesis regulatory)|reactome:R-HSA-162699|reactome:R-HSA-162710|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377 ensembl:ENSG00000135845(gene)|ensembl:ENST00000344529(transcript)|ensembl:ENST00000367728(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0003824"(catalytic activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR009450(Phosphatidylinositol N-acetylglucosaminyltransferase)|reactome:R-HSA-162710|refseq:NP_002633.1|refseq:NP_714969.1 - - - figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-jy5)|taxid:9606(JY5 B-cell line) - 2021/03/05 2021/03/05 rogid:b1kR+UX6Sfr1TcOpQ0D4M3+xy8M9606 rogid:ei/cjqRAkgPWw+lZXNwZnF31C0I9606 rigid:8cm/n6jio/zt6RKJv8dCJFOr7+A false glutathione s tranferase tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0815"(confirmation by molecular weight)|psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O94777 uniprotkb:P37287 intact:EBI-9097061|uniprotkb:Q5XKK9|uniprotkb:Q6FGH3|ensembl:ENSP00000322181 intact:EBI-26643054|ensembl:ENSP00000442653|ensembl:ENSP00000369820|uniprotkb:B4E0V2|uniprotkb:Q16025|uniprotkb:Q16250 psi-mi:dpm2_human(display_long)|uniprotkb:DPM2(gene name)|psi-mi:DPM2(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 2(gene name synonym)|uniprotkb:My026(orf name) psi-mi:piga_human(display_long)|uniprotkb:PIGA(gene name)|psi-mi:PIGA(display_short)|uniprotkb:GlcNAc-PI synthesis protein(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class A protein(gene name synonym) psi-mi:"MI:0096"(pull down) Watanabe et al. (2000) imex:IM-28793|pubmed:10944123 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26871885|imex:IM-28793-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003854.1|ensembl:ENSG00000136908(gene)|ensembl:ENST00000314392(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0019348"(dolichol metabolic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035269"(protein O-linked mannosylation)|interpro:IPR009914(Dolichol phosphate-mannose biosynthesis regulatory)|reactome:R-HSA-162699|reactome:R-HSA-162710|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377 ensembl:ENSG00000165195(gene)|ensembl:ENST00000333590(transcript)|ensembl:ENST00000542278(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008194"(UDP-glycosyltransferase activity)|go:"GO:0009893"(positive regulation of metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016254"(preassembly of GPI anchor in ER membrane)|go:"GO:0017176"(phosphatidylinositol N-acetylglucosaminyltransferase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001296(Glycosyl transferase, group 1)|interpro:IPR013234(PIGA, GPI anchor biosynthesis)|interpro:IPR039507|reactome:R-HSA-162710|refseq:NP_002632.1|refseq:NP_065206.3|refseq:XP_016885070.1 - - - figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-jy5)|taxid:9606(JY5 B-cell line) - 2021/03/05 2021/03/05 rogid:b1kR+UX6Sfr1TcOpQ0D4M3+xy8M9606 rogid:I6+5aCa/vOj/P/1aQ6Jg+Z9gbXk9606 rigid:8cm/n6jio/zt6RKJv8dCJFOr7+A false glutathione s tranferase tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0815"(confirmation by molecular weight)|psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O94777 uniprotkb:Q9BRB3 intact:EBI-9097061|uniprotkb:Q5XKK9|uniprotkb:Q6FGH3|ensembl:ENSP00000322181 intact:EBI-2339260|uniprotkb:O14927|uniprotkb:A2IDE1|uniprotkb:Q96G00|uniprotkb:Q9UJH4|uniprotkb:Q96S22|uniprotkb:D3DU52|intact:EBI-28972732|ensembl:ENSP00000026218 psi-mi:dpm2_human(display_long)|uniprotkb:DPM2(gene name)|psi-mi:DPM2(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 2(gene name synonym)|uniprotkb:My026(orf name) psi-mi:pigq_human(display_long)|uniprotkb:PIGQ(gene name)|psi-mi:PIGQ(display_short)|uniprotkb:GPI1(gene name synonym)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class Q protein(gene name synonym)|uniprotkb:N-acetylglucosamyl transferase component GPI1(gene name synonym) psi-mi:"MI:0096"(pull down) Watanabe et al. (2000) imex:IM-28793|pubmed:10944123 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26871885|imex:IM-28793-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003854.1|ensembl:ENSG00000136908(gene)|ensembl:ENST00000314392(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0019348"(dolichol metabolic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035269"(protein O-linked mannosylation)|interpro:IPR009914(Dolichol phosphate-mannose biosynthesis regulatory)|reactome:R-HSA-162699|reactome:R-HSA-162710|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377 ensembl:ENSP00000026218|ensembl:ENST00000321878|ensembl:ENSP00000326674|ensembl:ENST00000409527|ensembl:ENSP00000386760|ensembl:ENST00000470411|ensembl:ENSP00000439650|refseq:NP_004195.2|refseq:NP_683721.1|ensembl:ENSG00000007541(gene)|ensembl:ENST00000026218(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017176"(phosphatidylinositol N-acetylglucosaminyltransferase activity)|interpro:IPR007720(N-acetylglucosaminyl transferase component)|reactome:R-HSA-162710 - - - figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-jy5)|taxid:9606(JY5 B-cell line) - 2021/03/05 2021/03/05 rogid:b1kR+UX6Sfr1TcOpQ0D4M3+xy8M9606 rogid:nL4mUBYkxZwFJqjKwdm7qAZU8NI9606 rigid:8cm/n6jio/zt6RKJv8dCJFOr7+A false glutathione s tranferase tag:n-n flag tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0815"(confirmation by molecular weight)|psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9P2X0 uniprotkb:O94777 intact:EBI-9087337|uniprotkb:Q5SR62|uniprotkb:Q5SR63|uniprotkb:Q9BXN4|uniprotkb:Q9BXN5|ensembl:ENSP00000344338|ensembl:ENSP00000357385 intact:EBI-9097061|uniprotkb:Q5XKK9|uniprotkb:Q6FGH3|ensembl:ENSP00000322181 psi-mi:dpm3_human(display_long)|uniprotkb:DPM3(gene name)|psi-mi:DPM3(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 3(gene name synonym)|uniprotkb:Dolichyl-phosphate beta-D-mannosyltransferase subunit 3(gene name synonym)|uniprotkb:Mannose-P-dolichol synthase subunit 3(gene name synonym)|uniprotkb:Prostin-1(gene name synonym) psi-mi:dpm2_human(display_long)|uniprotkb:DPM2(gene name)|psi-mi:DPM2(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 2(gene name synonym)|uniprotkb:My026(orf name) psi-mi:"MI:0096"(pull down) Watanabe et al. (2000) imex:IM-28793|pubmed:10944123 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26871963|imex:IM-28793-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016856987.1|refseq:NP_061846.2|refseq:NP_714963.1|ensembl:ENSG00000179085(gene)|ensembl:ENST00000341298(transcript)|ensembl:ENST00000368400(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0018406"(protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031501"(mannosyltransferase complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035268"(protein mannosylation)|go:"GO:0035269"(protein O-linked mannosylation)|interpro:IPR013174(Dolichol-phosphate mannosyltransferase subunit 3)|reactome:R-HSA-162699|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377 refseq:NP_003854.1|ensembl:ENSG00000136908(gene)|ensembl:ENST00000314392(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0019348"(dolichol metabolic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035269"(protein O-linked mannosylation)|interpro:IPR009914(Dolichol phosphate-mannose biosynthesis regulatory)|reactome:R-HSA-162699|reactome:R-HSA-162710|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377 - - - figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-jy5)|taxid:9606(JY5 B-cell line) - 2021/03/05 2021/03/05 rogid:0wf0wox4cCMWDiy9qDpf2l7NTps9606 rogid:b1kR+UX6Sfr1TcOpQ0D4M3+xy8M9606 rigid:7s8qdN9+gzcyHMg6Sq3bM6pEZgI false flag tag:n-n glutathione s tranferase tag:n-n - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9P2X0 uniprotkb:O60762 intact:EBI-9087337|uniprotkb:Q5SR62|uniprotkb:Q5SR63|uniprotkb:Q9BXN4|uniprotkb:Q9BXN5|ensembl:ENSP00000344338|ensembl:ENSP00000357385 intact:EBI-719526|uniprotkb:O15157|uniprotkb:Q96HK0|uniprotkb:Q6IB78|ensembl:ENSP00000360644 psi-mi:dpm3_human(display_long)|uniprotkb:DPM3(gene name)|psi-mi:DPM3(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 3(gene name synonym)|uniprotkb:Dolichyl-phosphate beta-D-mannosyltransferase subunit 3(gene name synonym)|uniprotkb:Mannose-P-dolichol synthase subunit 3(gene name synonym)|uniprotkb:Prostin-1(gene name synonym) psi-mi:dpm1_human(display_long)|uniprotkb:DPM1(gene name)|psi-mi:DPM1(display_short)|uniprotkb:Dolichol-phosphate mannose synthase subunit 1(gene name synonym)|uniprotkb:Dolichyl-phosphate beta-D-mannosyltransferase subunit 1(gene name synonym)|uniprotkb:Mannose-P-dolichol synthase subunit 1(gene name synonym) psi-mi:"MI:0096"(pull down) Watanabe et al. (2000) imex:IM-28793|pubmed:10944123 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26871971|imex:IM-28793-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016856987.1|refseq:NP_061846.2|refseq:NP_714963.1|ensembl:ENSG00000179085(gene)|ensembl:ENST00000341298(transcript)|ensembl:ENST00000368400(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0018406"(protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031501"(mannosyltransferase complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035268"(protein mannosylation)|go:"GO:0035269"(protein O-linked mannosylation)|interpro:IPR013174(Dolichol-phosphate mannosyltransferase subunit 3)|reactome:R-HSA-162699|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377 refseq:NP_003850.1|refseq:NP_001303963.1|refseq:NP_001303964.1|refseq:NP_001303965.1|ensembl:ENSG00000000419(gene)|ensembl:ENST00000371588(transcript)|go:"GO:0004169"(dolichyl-phosphate-mannose-protein mannosyltransferase activity)|go:"GO:0004582"(dolichyl-phosphate beta-D-mannosyltransferase activity)|go:"GO:0005537"(mannose binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006506"(GPI anchor biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0019348"(dolichol metabolic process)|go:"GO:0019673"(GDP-mannose metabolic process)|go:"GO:0033185"(dolichol-phosphate-mannose synthase complex)|go:"GO:0035268"(protein mannosylation)|go:"GO:0035269"(protein O-linked mannosylation)|go:"GO:0043178"(alcohol binding)|interpro:IPR001173(Glycosyl transferase, family 2)|interpro:IPR029044|interpro:IPR039528|mint:O60762|reactome:R-HSA-162699|reactome:R-HSA-4717374|reactome:R-HSA-4719360|reactome:R-HSA-4719377 - - - figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-jy5)|taxid:9606(JY5 B-cell line) - 2021/03/05 2021/03/05 rogid:0wf0wox4cCMWDiy9qDpf2l7NTps9606 rogid:znbNDwp7t238ByanlbQzsTMvwTY9606 rigid:gIZfToc36A0Y9+zRHcAdNqt4tgE false flag tag:n-n glutathione s tranferase tag:n-n - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P04075 uniprotkb:P04075 intact:EBI-709613|uniprotkb:Q6FH76|uniprotkb:Q96B15|uniprotkb:Q9BWD9|uniprotkb:B4DXI7|uniprotkb:Q6FI10|uniprotkb:Q9UCN2|ensembl:ENSP00000400452|ensembl:ENSP00000455700|ensembl:ENSP00000455800|ensembl:ENSP00000494188 intact:EBI-709613|uniprotkb:Q6FH76|uniprotkb:Q96B15|uniprotkb:Q9BWD9|uniprotkb:B4DXI7|uniprotkb:Q6FI10|uniprotkb:Q9UCN2|ensembl:ENSP00000400452|ensembl:ENSP00000455700|ensembl:ENSP00000455800|ensembl:ENSP00000494188 psi-mi:aldoa_human(display_long)|uniprotkb:Muscle-type aldolase(gene name synonym)|uniprotkb:Lung cancer antigen NY-LU-1(gene name synonym)|uniprotkb:ALDOA(gene name)|psi-mi:ALDOA(display_short)|uniprotkb:ALDA(gene name synonym) psi-mi:aldoa_human(display_long)|uniprotkb:Muscle-type aldolase(gene name synonym)|uniprotkb:Lung cancer antigen NY-LU-1(gene name synonym)|uniprotkb:ALDOA(gene name)|psi-mi:ALDOA(display_short)|uniprotkb:ALDA(gene name synonym) psi-mi:"MI:0096"(pull down) Watanabe et al. (2000) imex:IM-28793|pubmed:10944123 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26871981|imex:IM-28793-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000025.1|refseq:NP_001121089.1|refseq:NP_001230106.1|refseq:NP_908930.1|refseq:NP_908932.1|refseq:XP_011544070.1|ensembl:ENSG00000149925(gene)|ensembl:ENST00000412304(transcript)|ensembl:ENST00000563060(transcript)|ensembl:ENST00000569545(transcript)|ensembl:ENST00000643777(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0061827"(sperm head)|go:"GO:0070061"(fructose binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768|mint:P04075|rcsb pdb:1ALD|rcsb pdb:2ALD|rcsb pdb:4ALD|rcsb pdb:5KY6|reactome:R-HSA-114608|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70263 refseq:NP_000025.1|refseq:NP_001121089.1|refseq:NP_001230106.1|refseq:NP_908930.1|refseq:NP_908932.1|refseq:XP_011544070.1|ensembl:ENSG00000149925(gene)|ensembl:ENST00000412304(transcript)|ensembl:ENST00000563060(transcript)|ensembl:ENST00000569545(transcript)|ensembl:ENST00000643777(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0061827"(sperm head)|go:"GO:0070061"(fructose binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768|mint:P04075|rcsb pdb:1ALD|rcsb pdb:2ALD|rcsb pdb:4ALD|rcsb pdb:5KY6|reactome:R-HSA-114608|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70263 - - - figure legend:fig.5a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-jy5)|taxid:9606(JY5 B-cell line) - 2021/03/05 2021/03/05 rogid:/UgTtKPQj2ZyKznKIfE9OVUcDFI9606 rogid:/UgTtKPQj2ZyKznKIfE9OVUcDFI9606 rigid:bC3/H/xNwmJPfb+zReW90IR561c false flag tag:n-n glutathione s tranferase tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)