#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P0C6X7-PRO_0000037322	uniprotkb:P0C6X7-PRO_0000037317	intact:EBI-25487235	intact:EBI-25487277	psi-mi:p0c6x7-pro_0000037322(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)	psi-mi:p0c6x7-pro_0000037317(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0018"(two hybrid)	Ke et al. (2012)	pubmed:22659295|imex:IM-28181	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25752045|imex:IM-28181-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent)	intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent)	-	chain-seq-start:6776|chain-seq-end:7073	chain-seq-start:4231|chain-seq-end:4369	figure legend:1|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/09	2020/07/09	rogid:SYi6CHEL+D0LFE6T2uZL+Kofqg8694009	rogid:/fARNiV2WEOqFni2l3o4/cqF7Bk694009	rigid:csogBbzGyWhdeBO3qN7j1Qe1hgo	false	-	sufficient binding region:65-107	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0C6X7-PRO_0000037317	uniprotkb:P0C6X7-PRO_0000037322	intact:EBI-25487277	intact:EBI-25487235	psi-mi:p0c6x7-pro_0000037317(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:p0c6x7-pro_0000037322(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)	psi-mi:"MI:0515"(methyltransferase assay)	Ke et al. (2012)	pubmed:22659295|imex:IM-28181	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	psi-mi:"MI:0213"(methylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25752076|imex:IM-28181-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent)	intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent)	go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")	chain-seq-start:4231|chain-seq-end:4369	chain-seq-start:6776|chain-seq-end:7073	figure legend:2C,  Lanes 12,15,16.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/07/09	2020/07/10	rogid:/fARNiV2WEOqFni2l3o4/cqF7Bk694009	rogid:SYi6CHEL+D0LFE6T2uZL+Kofqg8694009	-	false	necessary binding region:108-120,42-64|his tag:?-?	his tag:n-n	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:P0C6X7-PRO_0000037317	ddbj/embl/genbank:AY394850.2	intact:EBI-25487277	intact:EBI-25752087	psi-mi:p0c6x7-pro_0000037317(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:sars_rna_substrate(display_short)|psi-mi:AY394850.2(display_long)	psi-mi:"MI:0515"(methyltransferase assay)	Ke et al. (2012)	pubmed:22659295|imex:IM-28181	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	taxid:32630(synthetic construct)|taxid:32630(synthetic construct)	psi-mi:"MI:0213"(methylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25752076|imex:IM-28181-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0320"(ribonucleic acid)	intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent)	-	go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")	chain-seq-start:4231|chain-seq-end:4369	comment:"5′-terminal 259 nucleotides of the SARS-CoV genome, strain WHU, GenBank: AY394850.2, with first U mutated to a G (pmid:19208801)"	figure legend:2C,  Lanes 12,15,16.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/07/09	2020/07/10	rogid:/fARNiV2WEOqFni2l3o4/cqF7Bk694009	-	-	false	necessary binding region:108-120,42-64|his tag:?-?	32p radiolabel:1-1|carbohydrate chemical modification:1-1|RNA chemical modification:1-1	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:P0C6X7-PRO_0000037317	uniprotkb:P0C6X7-PRO_0000037320	intact:EBI-25487277	intact:EBI-25487328	psi-mi:p0c6x7-pro_0000037317(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:p0c6x7-pro_0000037320(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0515"(methyltransferase assay)	Ke et al. (2012)	pubmed:22659295|imex:IM-28181	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	psi-mi:"MI:0213"(methylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25752117|imex:IM-28181-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent)	intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent)	go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")	chain-seq-start:4231|chain-seq-end:4369	chain-seq-start:5903|chain-seq-end:6429	figure legend:2C,  Lanes 5,6,2.|comment:"A two-staged reaction: overall reaction = nsp10/nsp14/nsp16  methylates G*pppA-RNA to m7G*pppAm-RNA (Fig. 2C, lane 2): nsp14 first methylates G*pppA-RNA at N7 position of guanine (m7G) to generate  m7GpppA-RNA,  (Fig. 2C, lanes 1 and 7), followed by the methylation of m7G*pppA-RNA at the 2′-O-position of adenine (Am) to generate  m7G*pppAm-RNA."|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/07/09	2020/07/09	rogid:/fARNiV2WEOqFni2l3o4/cqF7Bk694009	rogid:FPQjk4Qo6mt2gs5v5hPwe+xPyrI694009	-	false	necessary binding region:42-64,108-120|his tag:?-?	his tag:n-n	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:P0C6X7-PRO_0000037317	uniprotkb:P0C6X7-PRO_0000037322	intact:EBI-25487277	intact:EBI-25487235	psi-mi:p0c6x7-pro_0000037317(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:p0c6x7-pro_0000037322(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)	psi-mi:"MI:0515"(methyltransferase assay)	Ke et al. (2012)	pubmed:22659295|imex:IM-28181	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	psi-mi:"MI:0213"(methylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25752117|imex:IM-28181-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent)	intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent)	go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")	chain-seq-start:4231|chain-seq-end:4369	chain-seq-start:6776|chain-seq-end:7073	figure legend:2C,  Lanes 5,6,2.|comment:"A two-staged reaction: overall reaction = nsp10/nsp14/nsp16  methylates G*pppA-RNA to m7G*pppAm-RNA (Fig. 2C, lane 2): nsp14 first methylates G*pppA-RNA at N7 position of guanine (m7G) to generate  m7GpppA-RNA,  (Fig. 2C, lanes 1 and 7), followed by the methylation of m7G*pppA-RNA at the 2′-O-position of adenine (Am) to generate  m7G*pppAm-RNA."|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/07/09	2020/07/09	rogid:/fARNiV2WEOqFni2l3o4/cqF7Bk694009	rogid:SYi6CHEL+D0LFE6T2uZL+Kofqg8694009	-	false	necessary binding region:42-64,108-120|his tag:?-?	his tag:n-n	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:P0C6X7-PRO_0000037317	ddbj/embl/genbank:AY394850.2	intact:EBI-25487277	intact:EBI-25752087	psi-mi:p0c6x7-pro_0000037317(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:sars_rna_substrate(display_short)|psi-mi:AY394850.2(display_long)	psi-mi:"MI:0515"(methyltransferase assay)	Ke et al. (2012)	pubmed:22659295|imex:IM-28181	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	taxid:32630(synthetic construct)|taxid:32630(synthetic construct)	psi-mi:"MI:0213"(methylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25752117|imex:IM-28181-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0320"(ribonucleic acid)	intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent)	-	go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")	chain-seq-start:4231|chain-seq-end:4369	comment:"5′-terminal 259 nucleotides of the SARS-CoV genome, strain WHU, GenBank: AY394850.2, with first U mutated to a G (pmid:19208801)"	figure legend:2C,  Lanes 5,6,2.|comment:"A two-staged reaction: overall reaction = nsp10/nsp14/nsp16  methylates G*pppA-RNA to m7G*pppAm-RNA (Fig. 2C, lane 2): nsp14 first methylates G*pppA-RNA at N7 position of guanine (m7G) to generate  m7GpppA-RNA,  (Fig. 2C, lanes 1 and 7), followed by the methylation of m7G*pppA-RNA at the 2′-O-position of adenine (Am) to generate  m7G*pppAm-RNA."|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/07/09	2020/07/09	rogid:/fARNiV2WEOqFni2l3o4/cqF7Bk694009	-	-	false	necessary binding region:42-64,108-120|his tag:?-?	RNA chemical modification:1-1|carbohydrate chemical modification:1-1|32p radiolabel:1-1|RNA chemical modification:1-1	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:P0C6X7-PRO_0000037320	ddbj/embl/genbank:AY394850.2	intact:EBI-25487328	intact:EBI-25752087	psi-mi:p0c6x7-pro_0000037320(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:sars_rna_substrate(display_short)|psi-mi:AY394850.2(display_long)	psi-mi:"MI:0515"(methyltransferase assay)	Ke et al. (2012)	pubmed:22659295|imex:IM-28181	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	taxid:32630(synthetic construct)|taxid:32630(synthetic construct)	psi-mi:"MI:0213"(methylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25752195|imex:IM-28181-7	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0320"(ribonucleic acid)	intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent)	-	go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")	chain-seq-start:5903|chain-seq-end:6429	comment:"5′-terminal 259 nucleotides of the SARS-CoV genome, strain WHU, GenBank: AY394850.2, with first U mutated to a G (pmid:19208801)"	figure legend:2C,  Lanes 1,7.|comment:"Reaction:  nsp14  methylates G*pppA-RNA at N7 position of guanine (m7G) to generate  m7GpppA-RNA,  (Fig. 2C, lanes 1 and 7).  Either protein nsp10 or nsp16 was present but did not participate in the reaction."|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/07/09	2020/07/09	rogid:FPQjk4Qo6mt2gs5v5hPwe+xPyrI694009	-	-	false	his tag:n-n	RNA chemical modification:1-1|32p radiolabel:1-1|RNA chemical modification:1-1	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:P0C6X7-PRO_0000037317	uniprotkb:P0C6X7-PRO_0000037322	intact:EBI-25487277	intact:EBI-25487235	psi-mi:p0c6x7-pro_0000037317(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:p0c6x7-pro_0000037322(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)	psi-mi:"MI:0030"(cross-linking study)	Ke et al. (2012)	pubmed:22659295|imex:IM-28181	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25753103|imex:IM-28181-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent)	intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent)	-	chain-seq-start:4231|chain-seq-end:4369	chain-seq-start:6776|chain-seq-end:7073	figure legend:2D, 4B|comment:All four truncated Nsp10 proteins attenuated the SAM binding affinity of nsp16.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/07/09	2020/07/10	rogid:/fARNiV2WEOqFni2l3o4/cqF7Bk694009	rogid:SYi6CHEL+D0LFE6T2uZL+Kofqg8694009	-	false	his tag:?-?	his tag:n-n	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
chebi:"CHEBI:15414"	uniprotkb:P0C6X7-PRO_0000037317	intact:EBI-980183	intact:EBI-25487277	psi-mi:s-adenosyl-l-methionine(display_short)|psi-mi:"CHEBI:15414"(display_long)	psi-mi:p0c6x7-pro_0000037317(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0030"(cross-linking study)	Ke et al. (2012)	pubmed:22659295|imex:IM-28181	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25753103|imex:IM-28181-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent)	-	-	chain-seq-start:4231|chain-seq-end:4369	figure legend:2D, 4B|comment:All four truncated Nsp10 proteins attenuated the SAM binding affinity of nsp16.|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/07/09	2020/07/10	-	rogid:/fARNiV2WEOqFni2l3o4/cqF7Bk694009	-	false	3h radiolabel:?-?	his tag:?-?	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:P0C6X7-PRO_0000037317	uniprotkb:P0C6X7-PRO_0000037317	intact:EBI-25487277	intact:EBI-25487277	psi-mi:p0c6x7-pro_0000037317(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:p0c6x7-pro_0000037317(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0030"(cross-linking study)	Ke et al. (2012)	pubmed:22659295|imex:IM-28181	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25753618|imex:IM-28181-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0941"(competitor)	psi-mi:"MI:0840"(stimulator)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent)	intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent)	-	chain-seq-start:4231|chain-seq-end:4369	chain-seq-start:4231|chain-seq-end:4369	figure legend:4B|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/07/09	2020/07/10	rogid:/fARNiV2WEOqFni2l3o4/cqF7Bk694009	rogid:/fARNiV2WEOqFni2l3o4/cqF7Bk694009	-	false	monoacetylated residue:68-68|sufficient binding region:68-96|amidated residue:96-96	his tag:?-?	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:P0C6X7-PRO_0000037317	uniprotkb:P0C6X7-PRO_0000037322	intact:EBI-25487277	intact:EBI-25487235	psi-mi:p0c6x7-pro_0000037317(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:p0c6x7-pro_0000037322(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)	psi-mi:"MI:0030"(cross-linking study)	Ke et al. (2012)	pubmed:22659295|imex:IM-28181	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25753618|imex:IM-28181-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0941"(competitor)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent)	intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent)	-	chain-seq-start:4231|chain-seq-end:4369	chain-seq-start:6776|chain-seq-end:7073	figure legend:4B|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/07/09	2020/07/10	rogid:/fARNiV2WEOqFni2l3o4/cqF7Bk694009	rogid:SYi6CHEL+D0LFE6T2uZL+Kofqg8694009	-	false	monoacetylated residue:68-68|sufficient binding region:68-96|amidated residue:96-96	his tag:n-n	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
chebi:"CHEBI:15414"	uniprotkb:P0C6X7-PRO_0000037317	intact:EBI-980183	intact:EBI-25487277	psi-mi:s-adenosyl-l-methionine(display_short)|psi-mi:"CHEBI:15414"(display_long)	psi-mi:p0c6x7-pro_0000037317(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0030"(cross-linking study)	Ke et al. (2012)	pubmed:22659295|imex:IM-28181	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25753618|imex:IM-28181-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0941"(competitor)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent)	-	-	chain-seq-start:4231|chain-seq-end:4369	figure legend:4B|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/07/09	2020/07/10	-	rogid:/fARNiV2WEOqFni2l3o4/cqF7Bk694009	-	false	3h radiolabel:?-?	monoacetylated residue:68-68|sufficient binding region:68-96|amidated residue:96-96	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:P0C6X7-PRO_0000037317	uniprotkb:P0C6X7-PRO_0000037322	intact:EBI-25487277	intact:EBI-25487235	psi-mi:p0c6x7-pro_0000037317(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:p0c6x7-pro_0000037322(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)	psi-mi:"MI:0515"(methyltransferase assay)	Ke et al. (2012)	pubmed:22659295|imex:IM-28181	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	psi-mi:"MI:0213"(methylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25753541|imex:IM-28181-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent)	intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent)	go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")	chain-seq-start:4231|chain-seq-end:4369	chain-seq-start:6776|chain-seq-end:7073	figure legend:4A|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/07/09	2020/07/10	rogid:/fARNiV2WEOqFni2l3o4/cqF7Bk694009	rogid:SYi6CHEL+D0LFE6T2uZL+Kofqg8694009	-	false	his tag:?-?	his tag:n-n	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:P0C6X7-PRO_0000037317	ddbj/embl/genbank:AY394850.2	intact:EBI-25487277	intact:EBI-25752087	psi-mi:p0c6x7-pro_0000037317(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:sars_rna_substrate(display_short)|psi-mi:AY394850.2(display_long)	psi-mi:"MI:0515"(methyltransferase assay)	Ke et al. (2012)	pubmed:22659295|imex:IM-28181	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	taxid:32630(synthetic construct)|taxid:32630(synthetic construct)	psi-mi:"MI:0213"(methylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25753541|imex:IM-28181-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0320"(ribonucleic acid)	intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent)	-	go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")	chain-seq-start:4231|chain-seq-end:4369	comment:"5′-terminal 259 nucleotides of the SARS-CoV genome, strain WHU, GenBank: AY394850.2, with first U mutated to a G (pmid:19208801)"	figure legend:4A|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/07/09	2020/07/10	rogid:/fARNiV2WEOqFni2l3o4/cqF7Bk694009	-	-	false	his tag:?-?	carbohydrate chemical modification:1-1|RNA chemical modification:1-1	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:P0C6X7-PRO_0000037317	uniprotkb:P0C6X7-PRO_0000037317	intact:EBI-25487277	intact:EBI-25487277	psi-mi:p0c6x7-pro_0000037317(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:p0c6x7-pro_0000037317(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:"MI:0515"(methyltransferase assay)	Ke et al. (2012)	pubmed:22659295|imex:IM-28181	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	psi-mi:"MI:0213"(methylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25753563|imex:IM-28181-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0941"(competitor)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent)	intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent)	go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")	chain-seq-start:4231|chain-seq-end:4369	chain-seq-start:4231|chain-seq-end:4369	figure legend:4A,|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	ic50:160.0x10^-6(molar)	2020/07/09	2020/07/10	rogid:/fARNiV2WEOqFni2l3o4/cqF7Bk694009	rogid:/fARNiV2WEOqFni2l3o4/cqF7Bk694009	-	false	monoacetylated residue:69-69|sufficient binding region:69-80|amidated residue:80-80	his tag:?-?	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:P0C6X7-PRO_0000037317	uniprotkb:P0C6X7-PRO_0000037322	intact:EBI-25487277	intact:EBI-25487235	psi-mi:p0c6x7-pro_0000037317(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:p0c6x7-pro_0000037322(display_long)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)	psi-mi:"MI:0515"(methyltransferase assay)	Ke et al. (2012)	pubmed:22659295|imex:IM-28181	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	psi-mi:"MI:0213"(methylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25753563|imex:IM-28181-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0941"(competitor)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent)	intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent)	go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")	chain-seq-start:4231|chain-seq-end:4369	chain-seq-start:6776|chain-seq-end:7073	figure legend:4A,|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	ic50:160.0x10^-6(molar)	2020/07/09	2020/07/10	rogid:/fARNiV2WEOqFni2l3o4/cqF7Bk694009	rogid:SYi6CHEL+D0LFE6T2uZL+Kofqg8694009	-	false	monoacetylated residue:69-69|sufficient binding region:69-80|amidated residue:80-80	his tag:n-n	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:P0C6X7-PRO_0000037317	ddbj/embl/genbank:AY394850.2	intact:EBI-25487277	intact:EBI-25752087	psi-mi:p0c6x7-pro_0000037317(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name)	psi-mi:sars_rna_substrate(display_short)|psi-mi:AY394850.2(display_long)	psi-mi:"MI:0515"(methyltransferase assay)	Ke et al. (2012)	pubmed:22659295|imex:IM-28181	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	taxid:32630(synthetic construct)|taxid:32630(synthetic construct)	psi-mi:"MI:0213"(methylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25753563|imex:IM-28181-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0941"(competitor)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0320"(ribonucleic acid)	intact:EBI-7843867(chain-parent)|uniprotkb:P0C6X7(chain-parent)	-	go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")	chain-seq-start:4231|chain-seq-end:4369	comment:"5′-terminal 259 nucleotides of the SARS-CoV genome, strain WHU, GenBank: AY394850.2, with first U mutated to a G (pmid:19208801)"	figure legend:4A,|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	ic50:160.0x10^-6(molar)	2020/07/09	2020/07/10	rogid:/fARNiV2WEOqFni2l3o4/cqF7Bk694009	-	-	false	monoacetylated residue:69-69|sufficient binding region:69-80|amidated residue:80-80	RNA chemical modification:1-1|carbohydrate chemical modification:1-1	-	-	psi-mi:"MI:0866"(tag visualisation)	psi-mi:"MI:0866"(tag visualisation)