#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q96CS3	uniprotkb:Q8NBM4	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25744900|imex:IM-28143-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	-	-	-	figure legend:Fig. 7B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2020/06/30	2020/07/01	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rigid:v+KUFcwteNQ2XMAwI05x9I84UJ4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9UBU6	uniprotkb:Q86TM6	intact:EBI-6309101|intact:EBI-28967558|ensembl:ENSP00000259963|uniprotkb:B2R725	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	psi-mi:fa8a1_human(display_long)|uniprotkb:FAM8A1(gene name)|psi-mi:FAM8A1(display_short)|uniprotkb:AHCP(gene name synonym)|uniprotkb:Autosomal highly conserved protein(gene name synonym)	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25744904|imex:IM-28143-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000259963|ensembl:ENSG00000137414(gene)|ensembl:ENST00000259963(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|interpro:IPR010432(RDD)|interpro:IPR039871|refseq:NP_057339.1	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	-	-	-	figure legend:Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2020/06/30	2020/07/01	rogid:0HV6qye10bMGdnt9CiGztIacrHM9606	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rigid:qZ3pVXB2A45srfY5A5jNT3Yp/GA	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9UBU6	uniprotkb:Q9UBV2	intact:EBI-6309101|intact:EBI-28967558|ensembl:ENSP00000259963|uniprotkb:B2R725	intact:EBI-358766|uniprotkb:Q6UWT6|uniprotkb:Q9P1T9|uniprotkb:Q9UHK7|ensembl:ENSP00000337053	psi-mi:fa8a1_human(display_long)|uniprotkb:FAM8A1(gene name)|psi-mi:FAM8A1(display_short)|uniprotkb:AHCP(gene name synonym)|uniprotkb:Autosomal highly conserved protein(gene name synonym)	psi-mi:se1l1_human(display_long)|uniprotkb:SEL1L(gene name)|psi-mi:SEL1L(display_short)|uniprotkb:TSA305(gene name synonym)|uniprotkb:UNQ128/PRO1063(orf name)|uniprotkb:Suppressor of lin-12-like protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25744904|imex:IM-28143-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000259963|ensembl:ENSG00000137414(gene)|ensembl:ENST00000259963(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|interpro:IPR010432(RDD)|interpro:IPR039871|refseq:NP_057339.1	refseq:NP_001231913.1|refseq:NP_005056.3|ensembl:ENSG00000071537(gene)|ensembl:ENST00000336735(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0050821"(protein stabilization)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|mint:Q9UBV2|reactome:R-HSA-1912420|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-46259N	-	-	-	figure legend:Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2020/06/30	2020/07/01	rogid:0HV6qye10bMGdnt9CiGztIacrHM9606	rogid:eufE+8nfcHK8CDl+AQ5G+3NtL+09606	rigid:qZ3pVXB2A45srfY5A5jNT3Yp/GA	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9UKV5	uniprotkb:Q8NBM4	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:"MI:0663"(confocal microscopy)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25744917|imex:IM-28143-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	-	-	-	figure legend:Fig. 7E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/06/30	2020/07/01	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rigid:YlB3odTjaEk4QRKc6HbYp/X6sHU	false	s tag:c-c	s tag:c-c	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q86TM6	uniprotkb:Q9UBU6	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	intact:EBI-6309101|intact:EBI-28967558|ensembl:ENSP00000259963|uniprotkb:B2R725	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:fa8a1_human(display_long)|uniprotkb:FAM8A1(gene name)|psi-mi:FAM8A1(display_short)|uniprotkb:AHCP(gene name synonym)|uniprotkb:Autosomal highly conserved protein(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25744932|imex:IM-28143-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	ensembl:ENSP00000259963|ensembl:ENSG00000137414(gene)|ensembl:ENST00000259963(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|interpro:IPR010432(RDD)|interpro:IPR039871|refseq:NP_057339.1	-	-	-	figure legend:Fig. 6E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/06/30	2020/07/01	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rogid:0HV6qye10bMGdnt9CiGztIacrHM9606	rigid:yWw5qzornlR7p8w1I2aE6ogOzpE	false	s tag:c-c	s tag:n-n	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q96DZ1	uniprotkb:Q9UBU6	intact:EBI-1023677|uniprotkb:O95901|uniprotkb:Q6UWN7|uniprotkb:Q9NUY7|uniprotkb:Q9UQL4|uniprotkb:B2RDB4|ensembl:ENSP00000185150|uniprotkb:B5MC72	intact:EBI-6309101|intact:EBI-28967558|ensembl:ENSP00000259963|uniprotkb:B2R725	psi-mi:erlec_human(display_long)|uniprotkb:ER lectin(gene name synonym)|uniprotkb:ERLEC1(gene name)|psi-mi:ERLEC1(display_short)|uniprotkb:XTP3TPB(gene name synonym)|uniprotkb:UNQ1878/PRO4321(orf name)|uniprotkb:C2orf30(gene name synonym)|uniprotkb:XTP3-transactivated gene B protein(gene name synonym)	psi-mi:fa8a1_human(display_long)|uniprotkb:FAM8A1(gene name)|psi-mi:FAM8A1(display_short)|uniprotkb:AHCP(gene name synonym)|uniprotkb:Autosomal highly conserved protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25745078|imex:IM-28143-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120870.1|refseq:NP_056516.2|ensembl:ENSG00000068912(gene)|ensembl:ENST00000185150(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR044865|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|refseq:NP_001120869.1	ensembl:ENSP00000259963|ensembl:ENSG00000137414(gene)|ensembl:ENST00000259963(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|interpro:IPR010432(RDD)|interpro:IPR039871|refseq:NP_057339.1	-	-	-	figure legend:Fig. 3A, 3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2020/06/30	2020/07/01	rogid:eBOyI1TfCgExBrXLxSwlUZ05NXs9606	rogid:0HV6qye10bMGdnt9CiGztIacrHM9606	rigid:wSHdyTob51HtFGtiT3o2BB/mSks	false	s tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96DZ1	uniprotkb:Q86TM6	intact:EBI-1023677|uniprotkb:O95901|uniprotkb:Q6UWN7|uniprotkb:Q9NUY7|uniprotkb:Q9UQL4|uniprotkb:B2RDB4|ensembl:ENSP00000185150|uniprotkb:B5MC72	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	psi-mi:erlec_human(display_long)|uniprotkb:ER lectin(gene name synonym)|uniprotkb:ERLEC1(gene name)|psi-mi:ERLEC1(display_short)|uniprotkb:XTP3TPB(gene name synonym)|uniprotkb:UNQ1878/PRO4321(orf name)|uniprotkb:C2orf30(gene name synonym)|uniprotkb:XTP3-transactivated gene B protein(gene name synonym)	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25745078|imex:IM-28143-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120870.1|refseq:NP_056516.2|ensembl:ENSG00000068912(gene)|ensembl:ENST00000185150(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR044865|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|refseq:NP_001120869.1	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	-	-	-	figure legend:Fig. 3A, 3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2020/06/30	2020/07/01	rogid:eBOyI1TfCgExBrXLxSwlUZ05NXs9606	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rigid:wSHdyTob51HtFGtiT3o2BB/mSks	false	s tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96DZ1	uniprotkb:Q9UBV2	intact:EBI-1023677|uniprotkb:O95901|uniprotkb:Q6UWN7|uniprotkb:Q9NUY7|uniprotkb:Q9UQL4|uniprotkb:B2RDB4|ensembl:ENSP00000185150|uniprotkb:B5MC72	intact:EBI-358766|uniprotkb:Q6UWT6|uniprotkb:Q9P1T9|uniprotkb:Q9UHK7|ensembl:ENSP00000337053	psi-mi:erlec_human(display_long)|uniprotkb:ER lectin(gene name synonym)|uniprotkb:ERLEC1(gene name)|psi-mi:ERLEC1(display_short)|uniprotkb:XTP3TPB(gene name synonym)|uniprotkb:UNQ1878/PRO4321(orf name)|uniprotkb:C2orf30(gene name synonym)|uniprotkb:XTP3-transactivated gene B protein(gene name synonym)	psi-mi:se1l1_human(display_long)|uniprotkb:SEL1L(gene name)|psi-mi:SEL1L(display_short)|uniprotkb:TSA305(gene name synonym)|uniprotkb:UNQ128/PRO1063(orf name)|uniprotkb:Suppressor of lin-12-like protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25745078|imex:IM-28143-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120870.1|refseq:NP_056516.2|ensembl:ENSG00000068912(gene)|ensembl:ENST00000185150(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR044865|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|refseq:NP_001120869.1	refseq:NP_001231913.1|refseq:NP_005056.3|ensembl:ENSG00000071537(gene)|ensembl:ENST00000336735(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0050821"(protein stabilization)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|mint:Q9UBV2|reactome:R-HSA-1912420|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-46259N	-	-	-	figure legend:Fig. 3A, 3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2020/06/30	2020/07/01	rogid:eBOyI1TfCgExBrXLxSwlUZ05NXs9606	rogid:eufE+8nfcHK8CDl+AQ5G+3NtL+09606	rigid:wSHdyTob51HtFGtiT3o2BB/mSks	false	s tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q13438	uniprotkb:Q86TM6	intact:EBI-725454|intact:EBI-1174342|uniprotkb:A6NDD1|uniprotkb:A6NFR7|uniprotkb:A6NLB2|uniprotkb:A8K5Q9|uniprotkb:B4DPX1|uniprotkb:B4E1I6|uniprotkb:E7ENT8|uniprotkb:F8VUH2|uniprotkb:O00579|uniprotkb:Q6IBL2|uniprotkb:Q8IZ58|uniprotkb:Q9BW99|uniprotkb:B4DE28|ensembl:ENSP00000318165|uniprotkb:E7EW91|uniprotkb:G3XA88	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	psi-mi:os9_human(display_long)|uniprotkb:OS9(gene name)|psi-mi:OS9(display_short)|uniprotkb:Amplified in osteosarcoma 9(gene name synonym)	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25745114|imex:IM-28143-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006803.1|refseq:NP_001017956.1|refseq:NP_001017957.1|refseq:NP_001017958.1|refseq:NP_001248349.1|refseq:NP_001248350.1|refseq:NP_001248351.1|refseq:NP_001248352.1|ensembl:ENSG00000135506(gene)|ensembl:ENST00000315970(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0002020"(protease binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006605"(protein targeting)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|interpro:IPR044865|rcsb pdb:3AIH|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-37493N	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	-	-	-	figure legend:Fig. 3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2020/06/30	2020/07/01	rogid:Ntc3geE7th+rBeIp0MxuUuu/28Y9606	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rigid:r5gT6ACjoSjUIY+L1YmhDlTiPYs	false	s tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q13438	uniprotkb:Q9UBV2	intact:EBI-725454|intact:EBI-1174342|uniprotkb:A6NDD1|uniprotkb:A6NFR7|uniprotkb:A6NLB2|uniprotkb:A8K5Q9|uniprotkb:B4DPX1|uniprotkb:B4E1I6|uniprotkb:E7ENT8|uniprotkb:F8VUH2|uniprotkb:O00579|uniprotkb:Q6IBL2|uniprotkb:Q8IZ58|uniprotkb:Q9BW99|uniprotkb:B4DE28|ensembl:ENSP00000318165|uniprotkb:E7EW91|uniprotkb:G3XA88	intact:EBI-358766|uniprotkb:Q6UWT6|uniprotkb:Q9P1T9|uniprotkb:Q9UHK7|ensembl:ENSP00000337053	psi-mi:os9_human(display_long)|uniprotkb:OS9(gene name)|psi-mi:OS9(display_short)|uniprotkb:Amplified in osteosarcoma 9(gene name synonym)	psi-mi:se1l1_human(display_long)|uniprotkb:SEL1L(gene name)|psi-mi:SEL1L(display_short)|uniprotkb:TSA305(gene name synonym)|uniprotkb:UNQ128/PRO1063(orf name)|uniprotkb:Suppressor of lin-12-like protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25745114|imex:IM-28143-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006803.1|refseq:NP_001017956.1|refseq:NP_001017957.1|refseq:NP_001017958.1|refseq:NP_001248349.1|refseq:NP_001248350.1|refseq:NP_001248351.1|refseq:NP_001248352.1|ensembl:ENSG00000135506(gene)|ensembl:ENST00000315970(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0002020"(protease binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006605"(protein targeting)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|interpro:IPR044865|rcsb pdb:3AIH|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-37493N	refseq:NP_001231913.1|refseq:NP_005056.3|ensembl:ENSG00000071537(gene)|ensembl:ENST00000336735(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0050821"(protein stabilization)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|mint:Q9UBV2|reactome:R-HSA-1912420|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-46259N	-	-	-	figure legend:Fig. 3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2020/06/30	2020/07/01	rogid:Ntc3geE7th+rBeIp0MxuUuu/28Y9606	rogid:eufE+8nfcHK8CDl+AQ5G+3NtL+09606	rigid:r5gT6ACjoSjUIY+L1YmhDlTiPYs	false	s tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9UBU6	uniprotkb:Q86TM6	intact:EBI-6309101|intact:EBI-28967558|ensembl:ENSP00000259963|uniprotkb:B2R725	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	psi-mi:fa8a1_human(display_long)|uniprotkb:FAM8A1(gene name)|psi-mi:FAM8A1(display_short)|uniprotkb:AHCP(gene name synonym)|uniprotkb:Autosomal highly conserved protein(gene name synonym)	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25745121|imex:IM-28143-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000259963|ensembl:ENSG00000137414(gene)|ensembl:ENST00000259963(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|interpro:IPR010432(RDD)|interpro:IPR039871|refseq:NP_057339.1	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	-	-	-	figure legend:Fig. 3F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2020/06/30	2020/07/01	rogid:0HV6qye10bMGdnt9CiGztIacrHM9606	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rigid:qZ3pVXB2A45srfY5A5jNT3Yp/GA	false	s tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9UBU6	uniprotkb:Q9UBV2	intact:EBI-6309101|intact:EBI-28967558|ensembl:ENSP00000259963|uniprotkb:B2R725	intact:EBI-358766|uniprotkb:Q6UWT6|uniprotkb:Q9P1T9|uniprotkb:Q9UHK7|ensembl:ENSP00000337053	psi-mi:fa8a1_human(display_long)|uniprotkb:FAM8A1(gene name)|psi-mi:FAM8A1(display_short)|uniprotkb:AHCP(gene name synonym)|uniprotkb:Autosomal highly conserved protein(gene name synonym)	psi-mi:se1l1_human(display_long)|uniprotkb:SEL1L(gene name)|psi-mi:SEL1L(display_short)|uniprotkb:TSA305(gene name synonym)|uniprotkb:UNQ128/PRO1063(orf name)|uniprotkb:Suppressor of lin-12-like protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25745121|imex:IM-28143-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000259963|ensembl:ENSG00000137414(gene)|ensembl:ENST00000259963(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|interpro:IPR010432(RDD)|interpro:IPR039871|refseq:NP_057339.1	refseq:NP_001231913.1|refseq:NP_005056.3|ensembl:ENSG00000071537(gene)|ensembl:ENST00000336735(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0050821"(protein stabilization)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|mint:Q9UBV2|reactome:R-HSA-1912420|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-46259N	-	-	-	figure legend:Fig. 3F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2020/06/30	2020/07/01	rogid:0HV6qye10bMGdnt9CiGztIacrHM9606	rogid:eufE+8nfcHK8CDl+AQ5G+3NtL+09606	rigid:qZ3pVXB2A45srfY5A5jNT3Yp/GA	false	s tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Y679	uniprotkb:Q86TM6	intact:EBI-1058701|ensembl:ENSP00000366748|uniprotkb:Q9H866|uniprotkb:Q9UNQ6|uniprotkb:Q9Y685|uniprotkb:C0H5W8	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	psi-mi:aup1_human(display_long)|uniprotkb:AUP1(gene name)|psi-mi:AUP1(display_short)|uniprotkb:Ancient ubiquitous protein 1(gene name synonym)	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25745128|imex:IM-28143-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115307(gene)|ensembl:ENST00000377526(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:NP_853553.1|go:"GO:0034389"(lipid droplet organization)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061724"(lipophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:0140042"(lipid droplet formation)|go:"GO:1990044"(protein localization to lipid droplet)|interpro:IPR003892(Ubiquitin system component Cue)|rcsb pdb:2EKF	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	-	-	-	figure legend:Fig. 3I|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2020/06/30	2020/07/01	rogid:6yySfIPpRUlnm0upBDYyfBUOtIY9606	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rigid:rdnKIvTwTg+Tau9jhXvV9U1hJYg	false	s tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Y679	uniprotkb:Q9UBV2	intact:EBI-1058701|ensembl:ENSP00000366748|uniprotkb:Q9H866|uniprotkb:Q9UNQ6|uniprotkb:Q9Y685|uniprotkb:C0H5W8	intact:EBI-358766|uniprotkb:Q6UWT6|uniprotkb:Q9P1T9|uniprotkb:Q9UHK7|ensembl:ENSP00000337053	psi-mi:aup1_human(display_long)|uniprotkb:AUP1(gene name)|psi-mi:AUP1(display_short)|uniprotkb:Ancient ubiquitous protein 1(gene name synonym)	psi-mi:se1l1_human(display_long)|uniprotkb:SEL1L(gene name)|psi-mi:SEL1L(display_short)|uniprotkb:TSA305(gene name synonym)|uniprotkb:UNQ128/PRO1063(orf name)|uniprotkb:Suppressor of lin-12-like protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25745128|imex:IM-28143-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115307(gene)|ensembl:ENST00000377526(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:NP_853553.1|go:"GO:0034389"(lipid droplet organization)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061724"(lipophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:0140042"(lipid droplet formation)|go:"GO:1990044"(protein localization to lipid droplet)|interpro:IPR003892(Ubiquitin system component Cue)|rcsb pdb:2EKF	refseq:NP_001231913.1|refseq:NP_005056.3|ensembl:ENSG00000071537(gene)|ensembl:ENST00000336735(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0050821"(protein stabilization)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|mint:Q9UBV2|reactome:R-HSA-1912420|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-46259N	-	-	-	figure legend:Fig. 3I|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2020/06/30	2020/07/01	rogid:6yySfIPpRUlnm0upBDYyfBUOtIY9606	rogid:eufE+8nfcHK8CDl+AQ5G+3NtL+09606	rigid:rdnKIvTwTg+Tau9jhXvV9U1hJYg	false	s tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96DZ1	uniprotkb:Q9UBV2	intact:EBI-1023677|uniprotkb:O95901|uniprotkb:Q6UWN7|uniprotkb:Q9NUY7|uniprotkb:Q9UQL4|uniprotkb:B2RDB4|ensembl:ENSP00000185150|uniprotkb:B5MC72	intact:EBI-358766|uniprotkb:Q6UWT6|uniprotkb:Q9P1T9|uniprotkb:Q9UHK7|ensembl:ENSP00000337053	psi-mi:erlec_human(display_long)|uniprotkb:ER lectin(gene name synonym)|uniprotkb:ERLEC1(gene name)|psi-mi:ERLEC1(display_short)|uniprotkb:XTP3TPB(gene name synonym)|uniprotkb:UNQ1878/PRO4321(orf name)|uniprotkb:C2orf30(gene name synonym)|uniprotkb:XTP3-transactivated gene B protein(gene name synonym)	psi-mi:se1l1_human(display_long)|uniprotkb:SEL1L(gene name)|psi-mi:SEL1L(display_short)|uniprotkb:TSA305(gene name synonym)|uniprotkb:UNQ128/PRO1063(orf name)|uniprotkb:Suppressor of lin-12-like protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25745138|imex:IM-28143-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120870.1|refseq:NP_056516.2|ensembl:ENSG00000068912(gene)|ensembl:ENST00000185150(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR044865|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|refseq:NP_001120869.1	refseq:NP_001231913.1|refseq:NP_005056.3|ensembl:ENSG00000071537(gene)|ensembl:ENST00000336735(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0050821"(protein stabilization)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|mint:Q9UBV2|reactome:R-HSA-1912420|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-46259N	-	-	-	figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2020/06/30	2020/07/01	rogid:eBOyI1TfCgExBrXLxSwlUZ05NXs9606	rogid:eufE+8nfcHK8CDl+AQ5G+3NtL+09606	rigid:v+Uq10TvjHlieTHE7R4AzFGoTEc	false	s tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96DZ1	uniprotkb:Q9Y385	intact:EBI-1023677|uniprotkb:O95901|uniprotkb:Q6UWN7|uniprotkb:Q9NUY7|uniprotkb:Q9UQL4|uniprotkb:B2RDB4|ensembl:ENSP00000185150|uniprotkb:B5MC72	intact:EBI-988826|uniprotkb:Q5W0N4|uniprotkb:Q9BZ32|uniprotkb:Q9NQL3|uniprotkb:Q9NY66|uniprotkb:Q9P011|uniprotkb:Q9P0S0|uniprotkb:Q9UF10|ensembl:ENSP00000451261|uniprotkb:A8K3F9|uniprotkb:Q53F25	psi-mi:erlec_human(display_long)|uniprotkb:ER lectin(gene name synonym)|uniprotkb:ERLEC1(gene name)|psi-mi:ERLEC1(display_short)|uniprotkb:XTP3TPB(gene name synonym)|uniprotkb:UNQ1878/PRO4321(orf name)|uniprotkb:C2orf30(gene name synonym)|uniprotkb:XTP3-transactivated gene B protein(gene name synonym)	psi-mi:ub2j1_human(display_long)|uniprotkb:Non-canonical ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:Yeast ubiquitin-conjugating enzyme UBC6 homolog E(gene name synonym)|uniprotkb:UBE2J1(gene name)|psi-mi:UBE2J1(display_short)|uniprotkb:NCUBE1(gene name synonym)|uniprotkb:CGI-76(orf name)|uniprotkb:HSPC153(orf name)|uniprotkb:HSPC205(orf name)|uniprotkb:E2 ubiquitin-conjugating enzyme J1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25745138|imex:IM-28143-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120870.1|refseq:NP_056516.2|ensembl:ENSG00000068912(gene)|ensembl:ENST00000185150(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR044865|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|refseq:NP_001120869.1	go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|reactome:R-HSA-983168|ensembl:ENSG00000198833(gene)|ensembl:ENST00000435041(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007286"(spermatid development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:NP_057105.2|dip:DIP-45598N	-	-	-	figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2020/06/30	2020/07/01	rogid:eBOyI1TfCgExBrXLxSwlUZ05NXs9606	rogid:nc3+V3Qxy1ZDhTWgTPLakJukxPM9606	rigid:v+Uq10TvjHlieTHE7R4AzFGoTEc	false	s tag:c-c	myc tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q86TM6	uniprotkb:Q9UBV2	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	intact:EBI-358766|uniprotkb:Q6UWT6|uniprotkb:Q9P1T9|uniprotkb:Q9UHK7|ensembl:ENSP00000337053	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:se1l1_human(display_long)|uniprotkb:SEL1L(gene name)|psi-mi:SEL1L(display_short)|uniprotkb:TSA305(gene name synonym)|uniprotkb:UNQ128/PRO1063(orf name)|uniprotkb:Suppressor of lin-12-like protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25745156|imex:IM-28143-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	refseq:NP_001231913.1|refseq:NP_005056.3|ensembl:ENSG00000071537(gene)|ensembl:ENST00000336735(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0050821"(protein stabilization)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|mint:Q9UBV2|reactome:R-HSA-1912420|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-46259N	-	-	-	figure legend:Fig. 3G|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2020/06/30	2020/07/01	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rogid:eufE+8nfcHK8CDl+AQ5G+3NtL+09606	rigid:2t3WSX/DwkAT4OQ2RVFVsmtt0Lk	false	s tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q86TM6	uniprotkb:Q9Y385	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	intact:EBI-988826|uniprotkb:Q5W0N4|uniprotkb:Q9BZ32|uniprotkb:Q9NQL3|uniprotkb:Q9NY66|uniprotkb:Q9P011|uniprotkb:Q9P0S0|uniprotkb:Q9UF10|ensembl:ENSP00000451261|uniprotkb:A8K3F9|uniprotkb:Q53F25	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:ub2j1_human(display_long)|uniprotkb:Non-canonical ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:Yeast ubiquitin-conjugating enzyme UBC6 homolog E(gene name synonym)|uniprotkb:UBE2J1(gene name)|psi-mi:UBE2J1(display_short)|uniprotkb:NCUBE1(gene name synonym)|uniprotkb:CGI-76(orf name)|uniprotkb:HSPC153(orf name)|uniprotkb:HSPC205(orf name)|uniprotkb:E2 ubiquitin-conjugating enzyme J1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25745156|imex:IM-28143-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|reactome:R-HSA-983168|ensembl:ENSG00000198833(gene)|ensembl:ENST00000435041(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007286"(spermatid development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:NP_057105.2|dip:DIP-45598N	-	-	-	figure legend:Fig. 3G|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2020/06/30	2020/07/01	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rogid:nc3+V3Qxy1ZDhTWgTPLakJukxPM9606	rigid:2t3WSX/DwkAT4OQ2RVFVsmtt0Lk	false	s tag:c-c	myc tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9UBV2	uniprotkb:Q86TM6	intact:EBI-358766|uniprotkb:Q6UWT6|uniprotkb:Q9P1T9|uniprotkb:Q9UHK7|ensembl:ENSP00000337053	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	psi-mi:se1l1_human(display_long)|uniprotkb:SEL1L(gene name)|psi-mi:SEL1L(display_short)|uniprotkb:TSA305(gene name synonym)|uniprotkb:UNQ128/PRO1063(orf name)|uniprotkb:Suppressor of lin-12-like protein 1(gene name synonym)	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25745165|imex:IM-28143-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001231913.1|refseq:NP_005056.3|ensembl:ENSG00000071537(gene)|ensembl:ENST00000336735(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0050821"(protein stabilization)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|mint:Q9UBV2|reactome:R-HSA-1912420|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-46259N	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	-	-	-	figure legend:Fig. 3H|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2020/06/30	2020/07/01	rogid:eufE+8nfcHK8CDl+AQ5G+3NtL+09606	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rigid:2t3WSX/DwkAT4OQ2RVFVsmtt0Lk	false	s tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9UBV2	uniprotkb:Q9Y385	intact:EBI-358766|uniprotkb:Q6UWT6|uniprotkb:Q9P1T9|uniprotkb:Q9UHK7|ensembl:ENSP00000337053	intact:EBI-988826|uniprotkb:Q5W0N4|uniprotkb:Q9BZ32|uniprotkb:Q9NQL3|uniprotkb:Q9NY66|uniprotkb:Q9P011|uniprotkb:Q9P0S0|uniprotkb:Q9UF10|ensembl:ENSP00000451261|uniprotkb:A8K3F9|uniprotkb:Q53F25	psi-mi:se1l1_human(display_long)|uniprotkb:SEL1L(gene name)|psi-mi:SEL1L(display_short)|uniprotkb:TSA305(gene name synonym)|uniprotkb:UNQ128/PRO1063(orf name)|uniprotkb:Suppressor of lin-12-like protein 1(gene name synonym)	psi-mi:ub2j1_human(display_long)|uniprotkb:Non-canonical ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:Yeast ubiquitin-conjugating enzyme UBC6 homolog E(gene name synonym)|uniprotkb:UBE2J1(gene name)|psi-mi:UBE2J1(display_short)|uniprotkb:NCUBE1(gene name synonym)|uniprotkb:CGI-76(orf name)|uniprotkb:HSPC153(orf name)|uniprotkb:HSPC205(orf name)|uniprotkb:E2 ubiquitin-conjugating enzyme J1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25745165|imex:IM-28143-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001231913.1|refseq:NP_005056.3|ensembl:ENSG00000071537(gene)|ensembl:ENST00000336735(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0050821"(protein stabilization)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|mint:Q9UBV2|reactome:R-HSA-1912420|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-46259N	go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|reactome:R-HSA-983168|ensembl:ENSG00000198833(gene)|ensembl:ENST00000435041(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007286"(spermatid development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:NP_057105.2|dip:DIP-45598N	-	-	-	figure legend:Fig. 3H|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2020/06/30	2020/07/01	rogid:eufE+8nfcHK8CDl+AQ5G+3NtL+09606	rogid:nc3+V3Qxy1ZDhTWgTPLakJukxPM9606	rigid:2t3WSX/DwkAT4OQ2RVFVsmtt0Lk	false	s tag:n-n	myc tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9Y679	uniprotkb:Q86TM6	intact:EBI-1058701|ensembl:ENSP00000366748|uniprotkb:Q9H866|uniprotkb:Q9UNQ6|uniprotkb:Q9Y685|uniprotkb:C0H5W8	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	psi-mi:aup1_human(display_long)|uniprotkb:AUP1(gene name)|psi-mi:AUP1(display_short)|uniprotkb:Ancient ubiquitous protein 1(gene name synonym)	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25745174|imex:IM-28143-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115307(gene)|ensembl:ENST00000377526(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:NP_853553.1|go:"GO:0034389"(lipid droplet organization)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061724"(lipophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:0140042"(lipid droplet formation)|go:"GO:1990044"(protein localization to lipid droplet)|interpro:IPR003892(Ubiquitin system component Cue)|rcsb pdb:2EKF	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	-	-	-	figure legend:Fig. 3J|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2020/06/30	2020/07/01	rogid:6yySfIPpRUlnm0upBDYyfBUOtIY9606	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rigid:7vR+vjtHLN++2TpYEmor+eJgUYE	false	s tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Y679	uniprotkb:P60604	intact:EBI-1058701|ensembl:ENSP00000366748|uniprotkb:Q9H866|uniprotkb:Q9UNQ6|uniprotkb:Q9Y685|uniprotkb:C0H5W8	intact:EBI-1051028|uniprotkb:P56554|uniprotkb:A8K3L4|uniprotkb:D3DSL7|uniprotkb:A6NMQ7|ensembl:ENSP00000338348	psi-mi:aup1_human(display_long)|uniprotkb:AUP1(gene name)|psi-mi:AUP1(display_short)|uniprotkb:Ancient ubiquitous protein 1(gene name synonym)	psi-mi:ub2g2_human(display_long)|uniprotkb:Ubiquitin-protein ligase G2(gene name synonym)|uniprotkb:Ubiquitin carrier protein G2(gene name synonym)|uniprotkb:UBE2G2(gene name)|psi-mi:UBE2G2(display_short)|uniprotkb:E2 ubiquitin-conjugating enzyme G2(gene name synonym)|uniprotkb:UBC7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25745174|imex:IM-28143-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115307(gene)|ensembl:ENST00000377526(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:NP_853553.1|go:"GO:0034389"(lipid droplet organization)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061724"(lipophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:0140042"(lipid droplet formation)|go:"GO:1990044"(protein localization to lipid droplet)|interpro:IPR003892(Ubiquitin system component Cue)|rcsb pdb:2EKF	refseq:NP_001189418.1|refseq:NP_003334.2|refseq:NP_872630.1|refseq:XP_016883958.1|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2CYX|rcsb pdb:2KLY|rcsb pdb:2LXP|rcsb pdb:3H8K|rcsb pdb:4LAD|reactome:R-HSA-8866652|reactome:R-HSA-983168|ensembl:ENSG00000184787(gene)|ensembl:ENST00000345496(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-50750N	-	-	-	figure legend:Fig. 3J|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2020/06/30	2020/07/01	rogid:6yySfIPpRUlnm0upBDYyfBUOtIY9606	rogid:Q/uslqX/WH/SxKEPYeMmU9CjTBI9606	rigid:7vR+vjtHLN++2TpYEmor+eJgUYE	false	s tag:c-c	myc tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8NBM4	uniprotkb:Q96CS3	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25745190|imex:IM-28143-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	-	-	-	figure legend:Fig. 3L, 3M|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2020/06/30	2020/07/01	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rigid:7qWpxNcGjA8aMPvoPVhxml60944	false	s tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8NBM4	uniprotkb:Q9UKV5	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25745190|imex:IM-28143-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	-	-	-	figure legend:Fig. 3L, 3M|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2020/06/30	2020/07/01	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rigid:7qWpxNcGjA8aMPvoPVhxml60944	false	s tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96CS3	uniprotkb:Q9GZP9	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-7962814|uniprotkb:Q9Y3A7|intact:MINT-3065126|ensembl:ENSP00000158771	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:derl2_human(display_long)|uniprotkb:DERL2(gene name)|psi-mi:DERL2(display_short)|uniprotkb:DER2(gene name synonym)|uniprotkb:FLANA(gene name synonym)|uniprotkb:CGI-101(orf name)|uniprotkb:SBBI53(orf name)|uniprotkb:Der1-like protein 2(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 2(gene name synonym)|uniprotkb:F-LAN-1(gene name synonym)|uniprotkb:F-LANa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25745197|imex:IM-28143-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_001291708.1|refseq:NP_057125.2|ensembl:ENSG00000072849(gene)|ensembl:ENST00000158771(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0001967"(suckling behavior)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032	-	-	comment:mint|function:"Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate. In contrast to DERL1, it is not involved in the degradation of MHC class I heavy chains following infection by cytomegaloviruses. May play a role in cell proliferation"	figure legend:Fig. 3N, 3O, 3P|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2020/06/30	2020/07/01	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:hoayS/Xn9+pq/C61NYRu/1aOm6s9606	rigid:Tkr1rsW3/DbCpsy/fuvBxi/9QlU	false	s tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96CS3	uniprotkb:Q8NBM4	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25745197|imex:IM-28143-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	-	-	-	figure legend:Fig. 3N, 3O, 3P|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2020/06/30	2020/07/01	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rigid:Tkr1rsW3/DbCpsy/fuvBxi/9QlU	false	s tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96CS3	uniprotkb:Q9UKV5	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25745197|imex:IM-28143-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	-	-	-	figure legend:Fig. 3N, 3O, 3P|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2020/06/30	2020/07/01	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rigid:Tkr1rsW3/DbCpsy/fuvBxi/9QlU	false	s tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O94905	uniprotkb:O75477	intact:EBI-4400770|uniprotkb:A0JLQ1|uniprotkb:A8K5S9|uniprotkb:B4DM38|uniprotkb:D3DSW0|uniprotkb:Q6NW21|uniprotkb:Q86VS6|uniprotkb:Q86W49|ensembl:ENSP00000428112	intact:EBI-359299|uniprotkb:B0QZ42|uniprotkb:Q53HV0|ensembl:ENSP00000384900|ensembl:ENSP00000410964|intact:EBI-21351077|uniprotkb:D3DR65	psi-mi:erln2_human(display_long)|uniprotkb:ERLIN2(gene name)|psi-mi:ERLIN2(display_short)|uniprotkb:C8orf2(gene name synonym)|uniprotkb:SPFH2(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 2(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2(gene name synonym)|uniprotkb:UNQ2441/PRO5003/PRO9924(orf name)	psi-mi:erln1_human(display_long)|uniprotkb:KEO4(gene name synonym)|uniprotkb:ERLIN1(gene name)|psi-mi:ERLIN1(display_short)|uniprotkb:C10orf69(gene name synonym)|uniprotkb:KE04(gene name synonym)|uniprotkb:SPFH1(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 1(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1(gene name synonym)|uniprotkb:Protein KE04(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25769871|imex:IM-28143-68	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001003790.1|refseq:NP_001003791.1|refseq:NP_009106.1|refseq:XP_016868489.1|refseq:XP_005273449.1|ensembl:ENSG00000147475(gene)|ensembl:ENST00000519638(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045121"(membrane raft)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O94905|reactome:R-HSA-382556|reactome:R-HSA-5655302|reactome:R-HSA-5678895|reactome:R-HSA-8853336	refseq:NP_001094096.1|refseq:NP_006450.2|ensembl:ENSG00000107566(gene)|ensembl:ENST00000407654(transcript)|ensembl:ENST00000421367(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O75477|reactome:R-HSA-382556|reactome:R-HSA-5678895|refseq:NP_001334786.1|refseq:NP_001334788.1|refseq:NP_001334789.1|refseq:NP_001334790.1|genbank_nucl_gi:67461552(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:Evjg3G0FFeQ499BNlJxpK6t8to89606	rogid:HycFhL5qL5GLmaIIc9NtTcBbu1M9606	rigid:AwK6PqZeei+rzf01RFnH8VgK9Es	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O94905	uniprotkb:Q9NY65	intact:EBI-4400770|uniprotkb:A0JLQ1|uniprotkb:A8K5S9|uniprotkb:B4DM38|uniprotkb:D3DSW0|uniprotkb:Q6NW21|uniprotkb:Q86VS6|uniprotkb:Q86W49|ensembl:ENSP00000428112	intact:EBI-356246|ensembl:ENSP00000333326|uniprotkb:B3KPW9|uniprotkb:Q2M3N4|uniprotkb:B2RCX2|uniprotkb:B4DWG3	psi-mi:erln2_human(display_long)|uniprotkb:ERLIN2(gene name)|psi-mi:ERLIN2(display_short)|uniprotkb:C8orf2(gene name synonym)|uniprotkb:SPFH2(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 2(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2(gene name synonym)|uniprotkb:UNQ2441/PRO5003/PRO9924(orf name)	psi-mi:tba8_human(display_long)|uniprotkb:TUBA8(gene name)|psi-mi:TUBA8(display_short)|uniprotkb:TUBAL2(gene name synonym)|uniprotkb:Alpha-tubulin 8(gene name synonym)|uniprotkb:Tubulin alpha chain-like 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25769871|imex:IM-28143-68	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001003790.1|refseq:NP_001003791.1|refseq:NP_009106.1|refseq:XP_016868489.1|refseq:XP_005273449.1|ensembl:ENSG00000147475(gene)|ensembl:ENST00000519638(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045121"(membrane raft)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O94905|reactome:R-HSA-382556|reactome:R-HSA-5655302|reactome:R-HSA-5678895|reactome:R-HSA-8853336	reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_001180343.1|refseq:NP_061816.1|ensembl:ENSG00000183785(gene)|ensembl:ENST00000330423(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5617833|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|dip:DIP-40751N|genbank_nucl_gi:12585376(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:Evjg3G0FFeQ499BNlJxpK6t8to89606	rogid:OGRoBAwLchNlK3LtAWkbSbCcxPQ9606	rigid:AwK6PqZeei+rzf01RFnH8VgK9Es	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y679	uniprotkb:Q14008	intact:EBI-1058701|ensembl:ENSP00000366748|uniprotkb:Q9H866|uniprotkb:Q9UNQ6|uniprotkb:Q9Y685|uniprotkb:C0H5W8	intact:EBI-310585|uniprotkb:Q0VAX8|uniprotkb:Q14668|uniprotkb:Q05D70|uniprotkb:Q0VAX7|uniprotkb:Q2TA89|uniprotkb:Q6NSH4|intact:EBI-28968667|ensembl:ENSP00000432768	psi-mi:aup1_human(display_long)|uniprotkb:AUP1(gene name)|psi-mi:AUP1(display_short)|uniprotkb:Ancient ubiquitous protein 1(gene name synonym)	psi-mi:ckap5_human(display_long)|uniprotkb:CKAP5(gene name)|psi-mi:CKAP5(display_short)|uniprotkb:KIAA0097(gene name synonym)|uniprotkb:Colonic and hepatic tumor overexpressed gene protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25769932|imex:IM-28143-28	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115307(gene)|ensembl:ENST00000377526(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:NP_853553.1|go:"GO:0034389"(lipid droplet organization)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061724"(lipophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:0140042"(lipid droplet formation)|go:"GO:1990044"(protein localization to lipid droplet)|interpro:IPR003892(Ubiquitin system component Cue)|rcsb pdb:2EKF	ensembl:ENST00000312055|ensembl:ENSP00000310227|ensembl:ENST00000354558|ensembl:ENSP00000346566|ensembl:ENSP00000432768|refseq:NP_001008938.1|refseq:NP_055571.2|ensembl:ENSG00000175216(gene)|ensembl:ENST00000529230(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0050658"(RNA transport)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0061863"(microtubule plus end polymerase)|go:"GO:0090063"(positive regulation of microtubule nucleation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR024395|interpro:IPR034085|mint:Q14008|rcsb pdb:4QMI|rcsb pdb:4QMJ|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9648025|genbank_nucl_gi:57222563(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:6yySfIPpRUlnm0upBDYyfBUOtIY9606	rogid:3bgwyNEucxXwXdbxbJkJ07PC90w9606	rigid:MgnQQoXIxPMixHapamY1M5uPNkY	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y679	uniprotkb:P78527	intact:EBI-1058701|ensembl:ENSP00000366748|uniprotkb:Q9H866|uniprotkb:Q9UNQ6|uniprotkb:Q9Y685|uniprotkb:C0H5W8	intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420	psi-mi:aup1_human(display_long)|uniprotkb:AUP1(gene name)|psi-mi:AUP1(display_short)|uniprotkb:Ancient ubiquitous protein 1(gene name synonym)	psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25769932|imex:IM-28143-28	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115307(gene)|ensembl:ENST00000377526(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:NP_853553.1|go:"GO:0034389"(lipid droplet organization)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061724"(lipophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:0140042"(lipid droplet formation)|go:"GO:1990044"(protein localization to lipid droplet)|interpro:IPR003892(Ubiquitin system component Cue)|rcsb pdb:2EKF	refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N|genbank_nucl_gi:38258929(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:6yySfIPpRUlnm0upBDYyfBUOtIY9606	rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606	rigid:MgnQQoXIxPMixHapamY1M5uPNkY	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y679	uniprotkb:P60604	intact:EBI-1058701|ensembl:ENSP00000366748|uniprotkb:Q9H866|uniprotkb:Q9UNQ6|uniprotkb:Q9Y685|uniprotkb:C0H5W8	intact:EBI-1051028|uniprotkb:P56554|uniprotkb:A8K3L4|uniprotkb:D3DSL7|uniprotkb:A6NMQ7|ensembl:ENSP00000338348	psi-mi:aup1_human(display_long)|uniprotkb:AUP1(gene name)|psi-mi:AUP1(display_short)|uniprotkb:Ancient ubiquitous protein 1(gene name synonym)	psi-mi:ub2g2_human(display_long)|uniprotkb:Ubiquitin-protein ligase G2(gene name synonym)|uniprotkb:Ubiquitin carrier protein G2(gene name synonym)|uniprotkb:UBE2G2(gene name)|psi-mi:UBE2G2(display_short)|uniprotkb:E2 ubiquitin-conjugating enzyme G2(gene name synonym)|uniprotkb:UBC7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25769932|imex:IM-28143-28	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115307(gene)|ensembl:ENST00000377526(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:NP_853553.1|go:"GO:0034389"(lipid droplet organization)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061724"(lipophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:0140042"(lipid droplet formation)|go:"GO:1990044"(protein localization to lipid droplet)|interpro:IPR003892(Ubiquitin system component Cue)|rcsb pdb:2EKF	refseq:NP_001189418.1|refseq:NP_003334.2|refseq:NP_872630.1|refseq:XP_016883958.1|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2CYX|rcsb pdb:2KLY|rcsb pdb:2LXP|rcsb pdb:3H8K|rcsb pdb:4LAD|reactome:R-HSA-8866652|reactome:R-HSA-983168|ensembl:ENSG00000184787(gene)|ensembl:ENST00000345496(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-50750N|genbank_nucl_gi:33359701(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:6yySfIPpRUlnm0upBDYyfBUOtIY9606	rogid:Q/uslqX/WH/SxKEPYeMmU9CjTBI9606	rigid:MgnQQoXIxPMixHapamY1M5uPNkY	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y679	uniprotkb:O15260	intact:EBI-1058701|ensembl:ENSP00000366748|uniprotkb:Q9H866|uniprotkb:Q9UNQ6|uniprotkb:Q9Y685|uniprotkb:C0H5W8	intact:EBI-1044848|uniprotkb:O60923|uniprotkb:Q9UNZ0|uniprotkb:Q9UNZ1|uniprotkb:Q5T8U6|ensembl:ENSP00000361057|ensembl:ENSP00000486049|uniprotkb:B7Z6A4	psi-mi:aup1_human(display_long)|uniprotkb:AUP1(gene name)|psi-mi:AUP1(display_short)|uniprotkb:Ancient ubiquitous protein 1(gene name synonym)	psi-mi:surf4_human(display_long)|uniprotkb:SURF4(gene name)|psi-mi:SURF4(display_short)|uniprotkb:SURF-4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25769932|imex:IM-28143-28	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115307(gene)|ensembl:ENST00000377526(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:NP_853553.1|go:"GO:0034389"(lipid droplet organization)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061724"(lipophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:0140042"(lipid droplet formation)|go:"GO:1990044"(protein localization to lipid droplet)|interpro:IPR003892(Ubiquitin system component Cue)|rcsb pdb:2EKF	refseq:NP_149351.1|ensembl:ENSG00000148248(gene)|ensembl:ENSG00000280951(gene)|ensembl:ENST00000629578(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035577"(azurophil granule membrane)|interpro:IPR002995(Surfeit locus 4)|mint:O15260|reactome:R-HSA-6798695|reactome:R-HSA-6811434|ensembl:ENST00000371989(transcript)|refseq:NP_001267718.1|refseq:NP_001267721.1|genbank_nucl_gi:12644052(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:6yySfIPpRUlnm0upBDYyfBUOtIY9606	rogid:VEkKSEfWLmSZx209HLRfoMMTzsg9606	rigid:MgnQQoXIxPMixHapamY1M5uPNkY	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O43402	uniprotkb:Q8N4V1	intact:EBI-741841|ensembl:ENSP00000253457|uniprotkb:C9JB21	intact:EBI-6163737|ensembl:ENSP00000306220|ensembl:ENSP00000505226|uniprotkb:B2R625|uniprotkb:B4DIY3|uniprotkb:D3DWG7|uniprotkb:Q5JPP7	psi-mi:emc8_human(display_long)|uniprotkb:EMC8(gene name)|psi-mi:EMC8(display_short)|uniprotkb:C16orf2(gene name synonym)|uniprotkb:C16orf4(gene name synonym)|uniprotkb:COX4AL(gene name synonym)|uniprotkb:COX4NB(gene name synonym)|uniprotkb:FAM158B(gene name synonym)|uniprotkb:NOC4(gene name synonym)|uniprotkb:Neighbor of COX4(gene name synonym)|uniprotkb:Protein FAM158B(gene name synonym)	psi-mi:emc5_human(display_long)|uniprotkb:MMGT1(gene name)|psi-mi:MMGT1(display_short)|uniprotkb:TMEM32(gene name synonym)|uniprotkb:Transmembrane protein 32(gene name synonym)|uniprotkb:EMC5(gene name synonym)|uniprotkb:Membrane magnesium transporter 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25769980|imex:IM-28143-30	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006058.1|ensembl:ENSG00000131148(gene)|ensembl:ENST00000253457(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6WW7|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_001135760.1	go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-5223345|ensembl:ENSG00000169446(gene)|ensembl:ENST00000305963(transcript)|ensembl:ENST00000679621(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|refseq:NP_775741.1|refseq:NP_001316929.1|genbank_nucl_gi:74751006(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:cGQFR1ZU2L/KgikqLELVUzplhTU9606	rogid:Kq+VEYt+fwoOsEfcgZ1K1vkFFN49606	rigid:cTCthogUWQ9W3EzFpJH2iW/MUXw	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O43402	uniprotkb:Q9NPA0	intact:EBI-741841|ensembl:ENSP00000253457|uniprotkb:C9JB21	intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5	psi-mi:emc8_human(display_long)|uniprotkb:EMC8(gene name)|psi-mi:EMC8(display_short)|uniprotkb:C16orf2(gene name synonym)|uniprotkb:C16orf4(gene name synonym)|uniprotkb:COX4AL(gene name synonym)|uniprotkb:COX4NB(gene name synonym)|uniprotkb:FAM158B(gene name synonym)|uniprotkb:NOC4(gene name synonym)|uniprotkb:Neighbor of COX4(gene name synonym)|uniprotkb:Protein FAM158B(gene name synonym)	psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25769980|imex:IM-28143-30	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006058.1|ensembl:ENSG00000131148(gene)|ensembl:ENST00000253457(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6WW7|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_001135760.1	ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1|genbank_nucl_gi:74752878(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:cGQFR1ZU2L/KgikqLELVUzplhTU9606	rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606	rigid:cTCthogUWQ9W3EzFpJH2iW/MUXw	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O43402	uniprotkb:Q8N766	intact:EBI-741841|ensembl:ENSP00000253457|uniprotkb:C9JB21	intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62	psi-mi:emc8_human(display_long)|uniprotkb:EMC8(gene name)|psi-mi:EMC8(display_short)|uniprotkb:C16orf2(gene name synonym)|uniprotkb:C16orf4(gene name synonym)|uniprotkb:COX4AL(gene name synonym)|uniprotkb:COX4NB(gene name synonym)|uniprotkb:FAM158B(gene name synonym)|uniprotkb:NOC4(gene name synonym)|uniprotkb:Neighbor of COX4(gene name synonym)|uniprotkb:Protein FAM158B(gene name synonym)	psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25769980|imex:IM-28143-30	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006058.1|ensembl:ENSG00000131148(gene)|ensembl:ENST00000253457(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6WW7|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_001135760.1	go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1|genbank_nucl_gi:74751081(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:cGQFR1ZU2L/KgikqLELVUzplhTU9606	rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606	rigid:cTCthogUWQ9W3EzFpJH2iW/MUXw	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O43402	uniprotkb:Q9BV81	intact:EBI-741841|ensembl:ENSP00000253457|uniprotkb:C9JB21	intact:EBI-2820492|ensembl:ENSP00000248378|ensembl:ENSP00000380322	psi-mi:emc8_human(display_long)|uniprotkb:EMC8(gene name)|psi-mi:EMC8(display_short)|uniprotkb:C16orf2(gene name synonym)|uniprotkb:C16orf4(gene name synonym)|uniprotkb:COX4AL(gene name synonym)|uniprotkb:COX4NB(gene name synonym)|uniprotkb:FAM158B(gene name synonym)|uniprotkb:NOC4(gene name synonym)|uniprotkb:Neighbor of COX4(gene name synonym)|uniprotkb:Protein FAM158B(gene name synonym)	psi-mi:emc6_human(display_long)|uniprotkb:EMC6(gene name)|psi-mi:EMC6(display_short)|uniprotkb:TMEM93(gene name synonym)|uniprotkb:Transmembrane protein 93(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25769980|imex:IM-28143-30	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006058.1|ensembl:ENSG00000131148(gene)|ensembl:ENST00000253457(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6WW7|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_001135760.1	refseq:NP_001014764.1|refseq:NP_112588.1|ensembl:ENSG00000127774(gene)|ensembl:ENST00000248378(transcript)|ensembl:ENST00000397133(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0097631"(integral component of omegasome membrane)|interpro:IPR008504(Protein of unknown function DUF786)|interpro:IPR029008|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|go:"GO:0072546"(EMC complex)|genbank_nucl_gi:74733294(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:cGQFR1ZU2L/KgikqLELVUzplhTU9606	rogid:GPnTCJqAA2eIiiP17pgtIhGnpsA9606	rigid:cTCthogUWQ9W3EzFpJH2iW/MUXw	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O43402	uniprotkb:Q5UCC4	intact:EBI-741841|ensembl:ENSP00000253457|uniprotkb:C9JB21	intact:EBI-11284388|uniprotkb:Q5UCC6|uniprotkb:Q69YT5|uniprotkb:Q6UWP3|uniprotkb:Q86YL4|uniprotkb:Q8N541|ensembl:ENSP00000334037	psi-mi:emc8_human(display_long)|uniprotkb:EMC8(gene name)|psi-mi:EMC8(display_short)|uniprotkb:C16orf2(gene name synonym)|uniprotkb:C16orf4(gene name synonym)|uniprotkb:COX4AL(gene name synonym)|uniprotkb:COX4NB(gene name synonym)|uniprotkb:FAM158B(gene name synonym)|uniprotkb:NOC4(gene name synonym)|uniprotkb:Neighbor of COX4(gene name synonym)|uniprotkb:Protein FAM158B(gene name synonym)	psi-mi:emc10_human(display_long)|uniprotkb:EMC10(gene name)|psi-mi:EMC10(display_short)|uniprotkb:C19orf63(gene name synonym)|uniprotkb:Hematopoietic signal peptide-containing membrane domain-containing protein 1(gene name synonym)|uniprotkb:INM02(gene name synonym)|uniprotkb:UNQ764/PRO1556(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25769980|imex:IM-28143-30	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006058.1|ensembl:ENSG00000131148(gene)|ensembl:ENST00000253457(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6WW7|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_001135760.1	refseq:NP_778233.4|refseq:NP_996261.1|ensembl:ENSG00000161671(gene)|ensembl:ENST00000334976(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005576"(extracellular region)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR029615|mint:Q5UCC4|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|genbank_nucl_gi:74708213(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:cGQFR1ZU2L/KgikqLELVUzplhTU9606	rogid:NEJjkw5uEJnzNUW7MkZIm/ELpA89606	rigid:cTCthogUWQ9W3EzFpJH2iW/MUXw	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O43402	uniprotkb:Q9P0I2	intact:EBI-741841|ensembl:ENSP00000253457|uniprotkb:C9JB21	intact:EBI-1054670|uniprotkb:Q53GH8|uniprotkb:Q6ZMC2|uniprotkb:B2R4Z9|ensembl:ENSP00000245046	psi-mi:emc8_human(display_long)|uniprotkb:EMC8(gene name)|psi-mi:EMC8(display_short)|uniprotkb:C16orf2(gene name synonym)|uniprotkb:C16orf4(gene name synonym)|uniprotkb:COX4AL(gene name synonym)|uniprotkb:COX4NB(gene name synonym)|uniprotkb:FAM158B(gene name synonym)|uniprotkb:NOC4(gene name synonym)|uniprotkb:Neighbor of COX4(gene name synonym)|uniprotkb:Protein FAM158B(gene name synonym)	psi-mi:emc3_human(display_long)|uniprotkb:EMC3(gene name)|psi-mi:EMC3(display_short)|uniprotkb:TMEM111(gene name synonym)|uniprotkb:Transmembrane protein 111(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25769980|imex:IM-28143-30	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006058.1|ensembl:ENSG00000131148(gene)|ensembl:ENST00000253457(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6WW7|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_001135760.1	refseq:NP_060917.1|ensembl:ENSG00000125037(gene)|ensembl:ENST00000245046(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008568(Protein of unknown function DUF850, transmembrane eukaryotic)|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-8980692|genbank_nucl_gi:71153383(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:cGQFR1ZU2L/KgikqLELVUzplhTU9606	rogid:VbIl0nFhcDMIPTxmBclaIMtbVU09606	rigid:cTCthogUWQ9W3EzFpJH2iW/MUXw	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O43402	uniprotkb:Q15006	intact:EBI-741841|ensembl:ENSP00000253457|uniprotkb:C9JB21	intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853	psi-mi:emc8_human(display_long)|uniprotkb:EMC8(gene name)|psi-mi:EMC8(display_short)|uniprotkb:C16orf2(gene name synonym)|uniprotkb:C16orf4(gene name synonym)|uniprotkb:COX4AL(gene name synonym)|uniprotkb:COX4NB(gene name synonym)|uniprotkb:FAM158B(gene name synonym)|uniprotkb:NOC4(gene name synonym)|uniprotkb:Neighbor of COX4(gene name synonym)|uniprotkb:Protein FAM158B(gene name synonym)	psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25769980|imex:IM-28143-30	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006058.1|ensembl:ENSG00000131148(gene)|ensembl:ENST00000253457(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6WW7|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_001135760.1	refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|genbank_nucl_gi:3183217(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:cGQFR1ZU2L/KgikqLELVUzplhTU9606	rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606	rigid:cTCthogUWQ9W3EzFpJH2iW/MUXw	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O43402	uniprotkb:Q8IYM0	intact:EBI-741841|ensembl:ENSP00000253457|uniprotkb:C9JB21	intact:EBI-6269645|uniprotkb:B4DZ15|intact:EBI-28984319|ensembl:ENSP00000257894|uniprotkb:Q8TCP7|uniprotkb:Q9H0L3	psi-mi:emc8_human(display_long)|uniprotkb:EMC8(gene name)|psi-mi:EMC8(display_short)|uniprotkb:C16orf2(gene name synonym)|uniprotkb:C16orf4(gene name synonym)|uniprotkb:COX4AL(gene name synonym)|uniprotkb:COX4NB(gene name synonym)|uniprotkb:FAM158B(gene name synonym)|uniprotkb:NOC4(gene name synonym)|uniprotkb:Neighbor of COX4(gene name synonym)|uniprotkb:Protein FAM158B(gene name synonym)	psi-mi:f186b_human(display_long)|uniprotkb:FAM186B(gene name)|psi-mi:FAM186B(display_short)|uniprotkb:C12orf25(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25769980|imex:IM-28143-30	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006058.1|ensembl:ENSG00000131148(gene)|ensembl:ENST00000253457(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6WW7|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_001135760.1	ensembl:ENSG00000135436(gene)|ensembl:ENST00000257894(transcript)|go:"GO:0032991"(protein-containing complex)|refseq:XP_011537098.1|ensembl:ENSP00000257894|refseq:XP_006719688.1|refseq:NP_115506.1|genbank_nucl_gi:158931119(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:cGQFR1ZU2L/KgikqLELVUzplhTU9606	rogid:MEuQQ4I444kV4y1Dsxi3B2xo+8E9606	rigid:cTCthogUWQ9W3EzFpJH2iW/MUXw	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O43402	uniprotkb:P02538	intact:EBI-741841|ensembl:ENSP00000253457|uniprotkb:C9JB21	intact:EBI-702198|uniprotkb:P48667|uniprotkb:Q08AR4|uniprotkb:Q6NT67|uniprotkb:Q96CL4|uniprotkb:A4QPC1|ensembl:ENSP00000369317	psi-mi:emc8_human(display_long)|uniprotkb:EMC8(gene name)|psi-mi:EMC8(display_short)|uniprotkb:C16orf2(gene name synonym)|uniprotkb:C16orf4(gene name synonym)|uniprotkb:COX4AL(gene name synonym)|uniprotkb:COX4NB(gene name synonym)|uniprotkb:FAM158B(gene name synonym)|uniprotkb:NOC4(gene name synonym)|uniprotkb:Neighbor of COX4(gene name synonym)|uniprotkb:Protein FAM158B(gene name synonym)	psi-mi:k2c6a_human(display_long)|uniprotkb:Cytokeratin-6A(gene name synonym)|uniprotkb:Keratin-6A(gene name synonym)|uniprotkb:Cytokeratin-6D(gene name synonym)|uniprotkb:KRT6A(gene name)|psi-mi:KRT6A(display_short)|uniprotkb:K6A(gene name synonym)|uniprotkb:KRT6D(gene name synonym)|uniprotkb:Type-II keratin Kb6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25769980|imex:IM-28143-30	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006058.1|ensembl:ENSG00000131148(gene)|ensembl:ENST00000253457(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6WW7|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_001135760.1	refseq:NP_005545.1|dip:DIP-533N|ensembl:ENSG00000205420(gene)|ensembl:ENST00000330722(transcript)|go:"GO:0001899"(negative regulation of cytolysis by symbiont of host cells)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0042060"(wound healing)|go:"GO:0045095"(keratin filament)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051838"(cytolysis by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000536"(negative regulation of entry of bacterium into host cell)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P02538|rcsb pdb:5KI0|reactome:R-HSA-6805567|reactome:R-HSA-6809371|genbank_nucl_gi:1346344(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:cGQFR1ZU2L/KgikqLELVUzplhTU9606	rogid:feIxUFTSMnjattUda5vdGhiL9H89606	rigid:cTCthogUWQ9W3EzFpJH2iW/MUXw	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O43402	uniprotkb:Q5J8M3	intact:EBI-741841|ensembl:ENSP00000253457|uniprotkb:C9JB21	intact:EBI-2814031|uniprotkb:Q9P0T9|uniprotkb:Q96KX9|uniprotkb:B4DJQ4|uniprotkb:Q9BUI5|uniprotkb:A8K3A9|ensembl:ENSP00000267750	psi-mi:emc8_human(display_long)|uniprotkb:EMC8(gene name)|psi-mi:EMC8(display_short)|uniprotkb:C16orf2(gene name synonym)|uniprotkb:C16orf4(gene name synonym)|uniprotkb:COX4AL(gene name synonym)|uniprotkb:COX4NB(gene name synonym)|uniprotkb:FAM158B(gene name synonym)|uniprotkb:NOC4(gene name synonym)|uniprotkb:Neighbor of COX4(gene name synonym)|uniprotkb:Protein FAM158B(gene name synonym)	psi-mi:emc4_human(display_long)|uniprotkb:EMC4(gene name)|psi-mi:EMC4(display_short)|uniprotkb:Cell proliferation-inducing gene 17 protein(gene name synonym)|uniprotkb:TMEM85(gene name synonym)|uniprotkb:Transmembrane protein 85(gene name synonym)|uniprotkb:HSPC184(orf name)|uniprotkb:PIG17(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25769980|imex:IM-28143-30	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006058.1|ensembl:ENSG00000131148(gene)|ensembl:ENST00000253457(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6WW7|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_001135760.1	refseq:NP_001273349.1|refseq:NP_057538.1|ensembl:ENSG00000128463(gene)|ensembl:ENST00000267750(transcript)|go:"GO:0006915"(apoptotic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR009445(Protein of unknown function DUF1077)|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|go:"GO:0016021"(integral component of membrane)|genbank_nucl_gi:115502869(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:cGQFR1ZU2L/KgikqLELVUzplhTU9606	rogid:b6qUbq3mJhmXTtZFctD6xd4E1jQ9606	rigid:cTCthogUWQ9W3EzFpJH2iW/MUXw	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86TM6	uniprotkb:Q9UBU6	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	intact:EBI-6309101|intact:EBI-28967558|ensembl:ENSP00000259963|uniprotkb:B2R725	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:fa8a1_human(display_long)|uniprotkb:FAM8A1(gene name)|psi-mi:FAM8A1(display_short)|uniprotkb:AHCP(gene name synonym)|uniprotkb:Autosomal highly conserved protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770331|imex:IM-28143-74	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032|genbank_nucl_gi:27436925(identity)	ensembl:ENSP00000259963|ensembl:ENSG00000137414(gene)|ensembl:ENST00000259963(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|interpro:IPR010432(RDD)|interpro:IPR039871|refseq:NP_057339.1	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rogid:0HV6qye10bMGdnt9CiGztIacrHM9606	rigid:yWw5qzornlR7p8w1I2aE6ogOzpE	false	-	s tag:?-?	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N766	uniprotkb:Q8N4V1	intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62	intact:EBI-6163737|ensembl:ENSP00000306220|ensembl:ENSP00000505226|uniprotkb:B2R625|uniprotkb:B4DIY3|uniprotkb:D3DWG7|uniprotkb:Q5JPP7	psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name)	psi-mi:emc5_human(display_long)|uniprotkb:MMGT1(gene name)|psi-mi:MMGT1(display_short)|uniprotkb:TMEM32(gene name synonym)|uniprotkb:Transmembrane protein 32(gene name synonym)|uniprotkb:EMC5(gene name synonym)|uniprotkb:Membrane magnesium transporter 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770244|imex:IM-28143-88	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1	go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-5223345|ensembl:ENSG00000169446(gene)|ensembl:ENST00000305963(transcript)|ensembl:ENST00000679621(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|refseq:NP_775741.1|refseq:NP_001316929.1|genbank_nucl_gi:74751006(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606	rogid:Kq+VEYt+fwoOsEfcgZ1K1vkFFN49606	rigid:MEstAcv1nEUqFgDAWU4f+mHsAaY	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N766	uniprotkb:Q9NPA0	intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62	intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5	psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name)	psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770244|imex:IM-28143-88	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1	ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1|genbank_nucl_gi:74752878(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606	rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606	rigid:MEstAcv1nEUqFgDAWU4f+mHsAaY	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N766	uniprotkb:Q9P0I2	intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62	intact:EBI-1054670|uniprotkb:Q53GH8|uniprotkb:Q6ZMC2|uniprotkb:B2R4Z9|ensembl:ENSP00000245046	psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name)	psi-mi:emc3_human(display_long)|uniprotkb:EMC3(gene name)|psi-mi:EMC3(display_short)|uniprotkb:TMEM111(gene name synonym)|uniprotkb:Transmembrane protein 111(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770244|imex:IM-28143-88	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1	refseq:NP_060917.1|ensembl:ENSG00000125037(gene)|ensembl:ENST00000245046(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008568(Protein of unknown function DUF850, transmembrane eukaryotic)|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-8980692|genbank_nucl_gi:71153383(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606	rogid:VbIl0nFhcDMIPTxmBclaIMtbVU09606	rigid:MEstAcv1nEUqFgDAWU4f+mHsAaY	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N766	uniprotkb:Q15006	intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62	intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853	psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name)	psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770244|imex:IM-28143-88	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1	refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|genbank_nucl_gi:3183217(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606	rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606	rigid:MEstAcv1nEUqFgDAWU4f+mHsAaY	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N766	uniprotkb:O43402	intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62	intact:EBI-741841|ensembl:ENSP00000253457|uniprotkb:C9JB21	psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name)	psi-mi:emc8_human(display_long)|uniprotkb:EMC8(gene name)|psi-mi:EMC8(display_short)|uniprotkb:C16orf2(gene name synonym)|uniprotkb:C16orf4(gene name synonym)|uniprotkb:COX4AL(gene name synonym)|uniprotkb:COX4NB(gene name synonym)|uniprotkb:FAM158B(gene name synonym)|uniprotkb:NOC4(gene name synonym)|uniprotkb:Neighbor of COX4(gene name synonym)|uniprotkb:Protein FAM158B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770244|imex:IM-28143-88	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1	refseq:NP_006058.1|ensembl:ENSG00000131148(gene)|ensembl:ENST00000253457(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6WW7|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_001135760.1|genbank_nucl_gi:18202040(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606	rogid:cGQFR1ZU2L/KgikqLELVUzplhTU9606	rigid:MEstAcv1nEUqFgDAWU4f+mHsAaY	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N766	uniprotkb:P06733	intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name)	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770244|imex:IM-28143-88	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|genbank_nucl_gi:119339(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	rigid:MEstAcv1nEUqFgDAWU4f+mHsAaY	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N766	uniprotkb:Q5J8M3	intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62	intact:EBI-2814031|uniprotkb:Q9P0T9|uniprotkb:Q96KX9|uniprotkb:B4DJQ4|uniprotkb:Q9BUI5|uniprotkb:A8K3A9|ensembl:ENSP00000267750	psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name)	psi-mi:emc4_human(display_long)|uniprotkb:EMC4(gene name)|psi-mi:EMC4(display_short)|uniprotkb:Cell proliferation-inducing gene 17 protein(gene name synonym)|uniprotkb:TMEM85(gene name synonym)|uniprotkb:Transmembrane protein 85(gene name synonym)|uniprotkb:HSPC184(orf name)|uniprotkb:PIG17(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770244|imex:IM-28143-88	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1	refseq:NP_001273349.1|refseq:NP_057538.1|ensembl:ENSG00000128463(gene)|ensembl:ENST00000267750(transcript)|go:"GO:0006915"(apoptotic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR009445(Protein of unknown function DUF1077)|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|go:"GO:0016021"(integral component of membrane)|genbank_nucl_gi:115502869(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606	rogid:b6qUbq3mJhmXTtZFctD6xd4E1jQ9606	rigid:MEstAcv1nEUqFgDAWU4f+mHsAaY	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N766	uniprotkb:P45880	intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62	intact:EBI-354022|ensembl:ENSP00000361686|ensembl:ENSP00000443092|uniprotkb:Q5VWK1|uniprotkb:Q5VWK3|uniprotkb:Q6IB40|uniprotkb:Q7L3J5|uniprotkb:Q9BWK8|uniprotkb:Q9Y5I6	psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name)	psi-mi:vdac2_human(display_long)|uniprotkb:VDAC2(gene name)|psi-mi:VDAC2(display_short)|uniprotkb:Outer mitochondrial membrane protein porin 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770244|imex:IM-28143-88	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1	ensembl:ENSG00000165637(gene)|ensembl:ENST00000332211(transcript)|ensembl:ENST00000543351(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006820"(anion transport)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031966"(mitochondrial membrane)|refseq:NP_001171712.1|refseq:NP_001171752.1|refseq:NP_003366.2|refseq:NP_001311017.1|go:"GO:0032272"(negative regulation of protein polymerization)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046930"(pore complex)|go:"GO:0097001"(ceramide binding)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030277|mint:P45880|reactome:R-HSA-5689880|reactome:R-HSA-8949215|genbank_nucl_gi:113412878(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606	rogid:seQxCd19Z2HmpXcwb48osAuuafA9606	rigid:MEstAcv1nEUqFgDAWU4f+mHsAaY	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9P0I2	uniprotkb:Q8N4V1	intact:EBI-1054670|uniprotkb:Q53GH8|uniprotkb:Q6ZMC2|uniprotkb:B2R4Z9|ensembl:ENSP00000245046	intact:EBI-6163737|ensembl:ENSP00000306220|ensembl:ENSP00000505226|uniprotkb:B2R625|uniprotkb:B4DIY3|uniprotkb:D3DWG7|uniprotkb:Q5JPP7	psi-mi:emc3_human(display_long)|uniprotkb:EMC3(gene name)|psi-mi:EMC3(display_short)|uniprotkb:TMEM111(gene name synonym)|uniprotkb:Transmembrane protein 111(gene name synonym)	psi-mi:emc5_human(display_long)|uniprotkb:MMGT1(gene name)|psi-mi:MMGT1(display_short)|uniprotkb:TMEM32(gene name synonym)|uniprotkb:Transmembrane protein 32(gene name synonym)|uniprotkb:EMC5(gene name synonym)|uniprotkb:Membrane magnesium transporter 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770481|imex:IM-28143-112	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060917.1|ensembl:ENSG00000125037(gene)|ensembl:ENST00000245046(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008568(Protein of unknown function DUF850, transmembrane eukaryotic)|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-8980692	go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-5223345|ensembl:ENSG00000169446(gene)|ensembl:ENST00000305963(transcript)|ensembl:ENST00000679621(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|refseq:NP_775741.1|refseq:NP_001316929.1|genbank_nucl_gi:74751006(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:VbIl0nFhcDMIPTxmBclaIMtbVU09606	rogid:Kq+VEYt+fwoOsEfcgZ1K1vkFFN49606	rigid:pt5sAjjwAumCOzzudKJnjqCorQI	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9P0I2	uniprotkb:Q9Y3B6	intact:EBI-1054670|uniprotkb:Q53GH8|uniprotkb:Q6ZMC2|uniprotkb:B2R4Z9|ensembl:ENSP00000245046	intact:EBI-748366|uniprotkb:Q9BUM3|uniprotkb:D3DS60|ensembl:ENSP00000216799|ensembl:ENSP00000403210|ensembl:ENSP00000494976|ensembl:ENSP00000495623	psi-mi:emc3_human(display_long)|uniprotkb:EMC3(gene name)|psi-mi:EMC3(display_short)|uniprotkb:TMEM111(gene name synonym)|uniprotkb:Transmembrane protein 111(gene name synonym)	psi-mi:emc9_human(display_long)|uniprotkb:EMC9(gene name)|psi-mi:EMC9(display_short)|uniprotkb:C14orf122(gene name synonym)|uniprotkb:FAM158A(gene name synonym)|uniprotkb:Protein FAM158A(gene name synonym)|uniprotkb:CGI-112(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770481|imex:IM-28143-112	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060917.1|ensembl:ENSG00000125037(gene)|ensembl:ENST00000245046(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008568(Protein of unknown function DUF850, transmembrane eukaryotic)|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-8980692	refseq:NP_057133.2|refseq:XP_005267778.1|ensembl:ENSG00000100908(gene)|ensembl:ENSG00000285377(gene)|ensembl:ENST00000216799(transcript)|ensembl:ENST00000419198(transcript)|ensembl:ENST00000642147(transcript)|ensembl:ENST00000646772(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6Y4L|rcsb pdb:6Z3W|genbank_nucl_gi:116241305(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:VbIl0nFhcDMIPTxmBclaIMtbVU09606	rogid:ZMbNxmOKb2r2KzWdB5JF/kGPSaU9606	rigid:pt5sAjjwAumCOzzudKJnjqCorQI	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9P0I2	uniprotkb:Q5J8M3	intact:EBI-1054670|uniprotkb:Q53GH8|uniprotkb:Q6ZMC2|uniprotkb:B2R4Z9|ensembl:ENSP00000245046	intact:EBI-2814031|uniprotkb:Q9P0T9|uniprotkb:Q96KX9|uniprotkb:B4DJQ4|uniprotkb:Q9BUI5|uniprotkb:A8K3A9|ensembl:ENSP00000267750	psi-mi:emc3_human(display_long)|uniprotkb:EMC3(gene name)|psi-mi:EMC3(display_short)|uniprotkb:TMEM111(gene name synonym)|uniprotkb:Transmembrane protein 111(gene name synonym)	psi-mi:emc4_human(display_long)|uniprotkb:EMC4(gene name)|psi-mi:EMC4(display_short)|uniprotkb:Cell proliferation-inducing gene 17 protein(gene name synonym)|uniprotkb:TMEM85(gene name synonym)|uniprotkb:Transmembrane protein 85(gene name synonym)|uniprotkb:HSPC184(orf name)|uniprotkb:PIG17(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770481|imex:IM-28143-112	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060917.1|ensembl:ENSG00000125037(gene)|ensembl:ENST00000245046(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008568(Protein of unknown function DUF850, transmembrane eukaryotic)|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-8980692	refseq:NP_001273349.1|refseq:NP_057538.1|ensembl:ENSG00000128463(gene)|ensembl:ENST00000267750(transcript)|go:"GO:0006915"(apoptotic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR009445(Protein of unknown function DUF1077)|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|go:"GO:0016021"(integral component of membrane)|genbank_nucl_gi:115502869(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:VbIl0nFhcDMIPTxmBclaIMtbVU09606	rogid:b6qUbq3mJhmXTtZFctD6xd4E1jQ9606	rigid:pt5sAjjwAumCOzzudKJnjqCorQI	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9P0I2	uniprotkb:Q9NPA0	intact:EBI-1054670|uniprotkb:Q53GH8|uniprotkb:Q6ZMC2|uniprotkb:B2R4Z9|ensembl:ENSP00000245046	intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5	psi-mi:emc3_human(display_long)|uniprotkb:EMC3(gene name)|psi-mi:EMC3(display_short)|uniprotkb:TMEM111(gene name synonym)|uniprotkb:Transmembrane protein 111(gene name synonym)	psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770481|imex:IM-28143-112	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060917.1|ensembl:ENSG00000125037(gene)|ensembl:ENST00000245046(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008568(Protein of unknown function DUF850, transmembrane eukaryotic)|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-8980692	ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1|genbank_nucl_gi:74752878(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:VbIl0nFhcDMIPTxmBclaIMtbVU09606	rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606	rigid:pt5sAjjwAumCOzzudKJnjqCorQI	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9P0I2	uniprotkb:Q8N766	intact:EBI-1054670|uniprotkb:Q53GH8|uniprotkb:Q6ZMC2|uniprotkb:B2R4Z9|ensembl:ENSP00000245046	intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62	psi-mi:emc3_human(display_long)|uniprotkb:EMC3(gene name)|psi-mi:EMC3(display_short)|uniprotkb:TMEM111(gene name synonym)|uniprotkb:Transmembrane protein 111(gene name synonym)	psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770481|imex:IM-28143-112	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060917.1|ensembl:ENSG00000125037(gene)|ensembl:ENST00000245046(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008568(Protein of unknown function DUF850, transmembrane eukaryotic)|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-8980692	go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1|genbank_nucl_gi:74751081(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:VbIl0nFhcDMIPTxmBclaIMtbVU09606	rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606	rigid:pt5sAjjwAumCOzzudKJnjqCorQI	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9P0I2	uniprotkb:Q5UCC4	intact:EBI-1054670|uniprotkb:Q53GH8|uniprotkb:Q6ZMC2|uniprotkb:B2R4Z9|ensembl:ENSP00000245046	intact:EBI-11284388|uniprotkb:Q5UCC6|uniprotkb:Q69YT5|uniprotkb:Q6UWP3|uniprotkb:Q86YL4|uniprotkb:Q8N541|ensembl:ENSP00000334037	psi-mi:emc3_human(display_long)|uniprotkb:EMC3(gene name)|psi-mi:EMC3(display_short)|uniprotkb:TMEM111(gene name synonym)|uniprotkb:Transmembrane protein 111(gene name synonym)	psi-mi:emc10_human(display_long)|uniprotkb:EMC10(gene name)|psi-mi:EMC10(display_short)|uniprotkb:C19orf63(gene name synonym)|uniprotkb:Hematopoietic signal peptide-containing membrane domain-containing protein 1(gene name synonym)|uniprotkb:INM02(gene name synonym)|uniprotkb:UNQ764/PRO1556(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770481|imex:IM-28143-112	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060917.1|ensembl:ENSG00000125037(gene)|ensembl:ENST00000245046(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008568(Protein of unknown function DUF850, transmembrane eukaryotic)|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-8980692	refseq:NP_778233.4|refseq:NP_996261.1|ensembl:ENSG00000161671(gene)|ensembl:ENST00000334976(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005576"(extracellular region)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR029615|mint:Q5UCC4|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|genbank_nucl_gi:74708213(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:VbIl0nFhcDMIPTxmBclaIMtbVU09606	rogid:NEJjkw5uEJnzNUW7MkZIm/ELpA89606	rigid:pt5sAjjwAumCOzzudKJnjqCorQI	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9P0I2	uniprotkb:Q15006	intact:EBI-1054670|uniprotkb:Q53GH8|uniprotkb:Q6ZMC2|uniprotkb:B2R4Z9|ensembl:ENSP00000245046	intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853	psi-mi:emc3_human(display_long)|uniprotkb:EMC3(gene name)|psi-mi:EMC3(display_short)|uniprotkb:TMEM111(gene name synonym)|uniprotkb:Transmembrane protein 111(gene name synonym)	psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770481|imex:IM-28143-112	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060917.1|ensembl:ENSG00000125037(gene)|ensembl:ENST00000245046(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008568(Protein of unknown function DUF850, transmembrane eukaryotic)|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-8980692	refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|genbank_nucl_gi:3183217(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:VbIl0nFhcDMIPTxmBclaIMtbVU09606	rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606	rigid:pt5sAjjwAumCOzzudKJnjqCorQI	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9P0I2	uniprotkb:O43402	intact:EBI-1054670|uniprotkb:Q53GH8|uniprotkb:Q6ZMC2|uniprotkb:B2R4Z9|ensembl:ENSP00000245046	intact:EBI-741841|ensembl:ENSP00000253457|uniprotkb:C9JB21	psi-mi:emc3_human(display_long)|uniprotkb:EMC3(gene name)|psi-mi:EMC3(display_short)|uniprotkb:TMEM111(gene name synonym)|uniprotkb:Transmembrane protein 111(gene name synonym)	psi-mi:emc8_human(display_long)|uniprotkb:EMC8(gene name)|psi-mi:EMC8(display_short)|uniprotkb:C16orf2(gene name synonym)|uniprotkb:C16orf4(gene name synonym)|uniprotkb:COX4AL(gene name synonym)|uniprotkb:COX4NB(gene name synonym)|uniprotkb:FAM158B(gene name synonym)|uniprotkb:NOC4(gene name synonym)|uniprotkb:Neighbor of COX4(gene name synonym)|uniprotkb:Protein FAM158B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770481|imex:IM-28143-112	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060917.1|ensembl:ENSG00000125037(gene)|ensembl:ENST00000245046(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008568(Protein of unknown function DUF850, transmembrane eukaryotic)|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-8980692	refseq:NP_006058.1|ensembl:ENSG00000131148(gene)|ensembl:ENST00000253457(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6WW7|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_001135760.1|genbank_nucl_gi:18202040(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:VbIl0nFhcDMIPTxmBclaIMtbVU09606	rogid:cGQFR1ZU2L/KgikqLELVUzplhTU9606	rigid:pt5sAjjwAumCOzzudKJnjqCorQI	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15006	uniprotkb:Q8N4V1	intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853	intact:EBI-6163737|ensembl:ENSP00000306220|ensembl:ENSP00000505226|uniprotkb:B2R625|uniprotkb:B4DIY3|uniprotkb:D3DWG7|uniprotkb:Q5JPP7	psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym)	psi-mi:emc5_human(display_long)|uniprotkb:MMGT1(gene name)|psi-mi:MMGT1(display_short)|uniprotkb:TMEM32(gene name synonym)|uniprotkb:Transmembrane protein 32(gene name synonym)|uniprotkb:EMC5(gene name synonym)|uniprotkb:Membrane magnesium transporter 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770445|imex:IM-28143-40	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP	go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-5223345|ensembl:ENSG00000169446(gene)|ensembl:ENST00000305963(transcript)|ensembl:ENST00000679621(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|refseq:NP_775741.1|refseq:NP_001316929.1|genbank_nucl_gi:74751006(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606	rogid:Kq+VEYt+fwoOsEfcgZ1K1vkFFN49606	rigid:Eu3MY4wI/8oEvPRU9p9tNmlEJpY	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15006	uniprotkb:Q9NPA0	intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853	intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5	psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym)	psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770445|imex:IM-28143-40	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP	ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1|genbank_nucl_gi:74752878(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606	rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606	rigid:Eu3MY4wI/8oEvPRU9p9tNmlEJpY	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15006	uniprotkb:Q8N766	intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853	intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62	psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym)	psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770445|imex:IM-28143-40	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP	go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1|genbank_nucl_gi:74751081(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606	rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606	rigid:Eu3MY4wI/8oEvPRU9p9tNmlEJpY	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15006	uniprotkb:Q9BV81	intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853	intact:EBI-2820492|ensembl:ENSP00000248378|ensembl:ENSP00000380322	psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym)	psi-mi:emc6_human(display_long)|uniprotkb:EMC6(gene name)|psi-mi:EMC6(display_short)|uniprotkb:TMEM93(gene name synonym)|uniprotkb:Transmembrane protein 93(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770445|imex:IM-28143-40	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP	refseq:NP_001014764.1|refseq:NP_112588.1|ensembl:ENSG00000127774(gene)|ensembl:ENST00000248378(transcript)|ensembl:ENST00000397133(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0097631"(integral component of omegasome membrane)|interpro:IPR008504(Protein of unknown function DUF786)|interpro:IPR029008|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|go:"GO:0072546"(EMC complex)|genbank_nucl_gi:74733294(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606	rogid:GPnTCJqAA2eIiiP17pgtIhGnpsA9606	rigid:Eu3MY4wI/8oEvPRU9p9tNmlEJpY	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15006	uniprotkb:Q5UCC4	intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853	intact:EBI-11284388|uniprotkb:Q5UCC6|uniprotkb:Q69YT5|uniprotkb:Q6UWP3|uniprotkb:Q86YL4|uniprotkb:Q8N541|ensembl:ENSP00000334037	psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym)	psi-mi:emc10_human(display_long)|uniprotkb:EMC10(gene name)|psi-mi:EMC10(display_short)|uniprotkb:C19orf63(gene name synonym)|uniprotkb:Hematopoietic signal peptide-containing membrane domain-containing protein 1(gene name synonym)|uniprotkb:INM02(gene name synonym)|uniprotkb:UNQ764/PRO1556(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770445|imex:IM-28143-40	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP	refseq:NP_778233.4|refseq:NP_996261.1|ensembl:ENSG00000161671(gene)|ensembl:ENST00000334976(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005576"(extracellular region)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR029615|mint:Q5UCC4|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|genbank_nucl_gi:74708213(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606	rogid:NEJjkw5uEJnzNUW7MkZIm/ELpA89606	rigid:Eu3MY4wI/8oEvPRU9p9tNmlEJpY	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15006	uniprotkb:Q9P0I2	intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853	intact:EBI-1054670|uniprotkb:Q53GH8|uniprotkb:Q6ZMC2|uniprotkb:B2R4Z9|ensembl:ENSP00000245046	psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym)	psi-mi:emc3_human(display_long)|uniprotkb:EMC3(gene name)|psi-mi:EMC3(display_short)|uniprotkb:TMEM111(gene name synonym)|uniprotkb:Transmembrane protein 111(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770445|imex:IM-28143-40	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP	refseq:NP_060917.1|ensembl:ENSG00000125037(gene)|ensembl:ENST00000245046(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008568(Protein of unknown function DUF850, transmembrane eukaryotic)|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-8980692|genbank_nucl_gi:71153383(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606	rogid:VbIl0nFhcDMIPTxmBclaIMtbVU09606	rigid:Eu3MY4wI/8oEvPRU9p9tNmlEJpY	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15006	uniprotkb:O43402	intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853	intact:EBI-741841|ensembl:ENSP00000253457|uniprotkb:C9JB21	psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym)	psi-mi:emc8_human(display_long)|uniprotkb:EMC8(gene name)|psi-mi:EMC8(display_short)|uniprotkb:C16orf2(gene name synonym)|uniprotkb:C16orf4(gene name synonym)|uniprotkb:COX4AL(gene name synonym)|uniprotkb:COX4NB(gene name synonym)|uniprotkb:FAM158B(gene name synonym)|uniprotkb:NOC4(gene name synonym)|uniprotkb:Neighbor of COX4(gene name synonym)|uniprotkb:Protein FAM158B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770445|imex:IM-28143-40	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP	refseq:NP_006058.1|ensembl:ENSG00000131148(gene)|ensembl:ENST00000253457(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6WW7|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_001135760.1|genbank_nucl_gi:18202040(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606	rogid:cGQFR1ZU2L/KgikqLELVUzplhTU9606	rigid:Eu3MY4wI/8oEvPRU9p9tNmlEJpY	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15006	uniprotkb:O75838	intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853	intact:EBI-25770403|ensembl:ENSP00000258930|uniprotkb:B4DDF0|uniprotkb:H0YM71|uniprotkb:Q05BT6	psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym)	psi-mi:cib2_human(display_long)|uniprotkb:CIB2(gene name)|psi-mi:CIB2(display_short)|uniprotkb:KIP2(gene name synonym)|uniprotkb:Kinase-interacting protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770445|imex:IM-28143-40	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP	go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0032420"(stereocilium)|go:"GO:0032437"(cuticular plate)|go:"GO:0042383"(sarcolemma)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0072562"(blood microparticle)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|reactome:R-HSA-9662360|reactome:R-HSA-9662361|go:"GO:0000287"(magnesium ion binding)|ensembl:ENSG00000136425(gene)|ensembl:ENST00000258930(transcript)|refseq:NP_001258817.1|refseq:NP_001258818.1|refseq:NP_001288153.1|refseq:NP_006374.1|refseq:XP_005254183.1|refseq:XP_006720437.1|genbank_nucl_gi:12230235(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606	rogid:a0V69Z5Y4/HPaMV2W4oTnuDH20U9606	rigid:Eu3MY4wI/8oEvPRU9p9tNmlEJpY	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15006	uniprotkb:Q9Y3B6	intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853	intact:EBI-748366|uniprotkb:Q9BUM3|uniprotkb:D3DS60|ensembl:ENSP00000216799|ensembl:ENSP00000403210|ensembl:ENSP00000494976|ensembl:ENSP00000495623	psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym)	psi-mi:emc9_human(display_long)|uniprotkb:EMC9(gene name)|psi-mi:EMC9(display_short)|uniprotkb:C14orf122(gene name synonym)|uniprotkb:FAM158A(gene name synonym)|uniprotkb:Protein FAM158A(gene name synonym)|uniprotkb:CGI-112(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770445|imex:IM-28143-40	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP	refseq:NP_057133.2|refseq:XP_005267778.1|ensembl:ENSG00000100908(gene)|ensembl:ENSG00000285377(gene)|ensembl:ENST00000216799(transcript)|ensembl:ENST00000419198(transcript)|ensembl:ENST00000642147(transcript)|ensembl:ENST00000646772(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6Y4L|rcsb pdb:6Z3W|genbank_nucl_gi:116241305(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606	rogid:ZMbNxmOKb2r2KzWdB5JF/kGPSaU9606	rigid:Eu3MY4wI/8oEvPRU9p9tNmlEJpY	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15006	uniprotkb:Q5J8M3	intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853	intact:EBI-2814031|uniprotkb:Q9P0T9|uniprotkb:Q96KX9|uniprotkb:B4DJQ4|uniprotkb:Q9BUI5|uniprotkb:A8K3A9|ensembl:ENSP00000267750	psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym)	psi-mi:emc4_human(display_long)|uniprotkb:EMC4(gene name)|psi-mi:EMC4(display_short)|uniprotkb:Cell proliferation-inducing gene 17 protein(gene name synonym)|uniprotkb:TMEM85(gene name synonym)|uniprotkb:Transmembrane protein 85(gene name synonym)|uniprotkb:HSPC184(orf name)|uniprotkb:PIG17(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770445|imex:IM-28143-40	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP	refseq:NP_001273349.1|refseq:NP_057538.1|ensembl:ENSG00000128463(gene)|ensembl:ENST00000267750(transcript)|go:"GO:0006915"(apoptotic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR009445(Protein of unknown function DUF1077)|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|go:"GO:0016021"(integral component of membrane)|genbank_nucl_gi:115502869(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606	rogid:b6qUbq3mJhmXTtZFctD6xd4E1jQ9606	rigid:Eu3MY4wI/8oEvPRU9p9tNmlEJpY	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9GZP9	uniprotkb:Q9NQC3	intact:EBI-7962814|uniprotkb:Q9Y3A7|intact:MINT-3065126|ensembl:ENSP00000158771	intact:EBI-715945|intact:EBI-1753019|uniprotkb:O94962|uniprotkb:Q9BXG5|uniprotkb:Q9H212|uniprotkb:Q9H3I3|uniprotkb:Q9UQ42|uniprotkb:Q9Y293|uniprotkb:Q9Y2Y7|uniprotkb:Q9Y5U6|intact:EBI-1958210|intact:EBI-1056082|uniprotkb:Q7L7Q8|uniprotkb:Q96B16|intact:EBI-28967519|ensembl:ENSP00000337838|uniprotkb:Q7L7Q5|uniprotkb:Q7L7Q6|uniprotkb:Q8IUA4	psi-mi:derl2_human(display_long)|uniprotkb:DERL2(gene name)|psi-mi:DERL2(display_short)|uniprotkb:DER2(gene name synonym)|uniprotkb:FLANA(gene name synonym)|uniprotkb:CGI-101(orf name)|uniprotkb:SBBI53(orf name)|uniprotkb:Der1-like protein 2(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 2(gene name synonym)|uniprotkb:F-LAN-1(gene name synonym)|uniprotkb:F-LANa(gene name synonym)	psi-mi:rtn4_human(display_long)|uniprotkb:Neurite outgrowth inhibitor(gene name synonym)|uniprotkb:Foocen(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:Neuroendocrine-specific protein C homolog(gene name synonym)|uniprotkb:RTN-x(gene name synonym)|uniprotkb:Reticulon-5(gene name synonym)|uniprotkb:RTN4(gene name)|psi-mi:RTN4(display_short)|uniprotkb:KIAA0886(gene name synonym)|uniprotkb:NOGO(gene name synonym)|uniprotkb:My043(orf name)|uniprotkb:SP1507(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770301|imex:IM-28143-110	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001291708.1|refseq:NP_057125.2|ensembl:ENSG00000072849(gene)|ensembl:ENST00000158771(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0001967"(suckling behavior)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032	ensembl:ENST00000317610|ensembl:ENSP00000322147|ensembl:ENSP00000337838|ensembl:ENST00000357376|ensembl:ENSP00000349944|ensembl:ENST00000357732|ensembl:ENSP00000350365|ensembl:ENST00000394609|ensembl:ENSP00000378107|ensembl:ENST00000394611|ensembl:ENSP00000378109|ensembl:ENST00000404909|ensembl:ENSP00000385650|ensembl:ENST00000405240|ensembl:ENSP00000384471|refseq:NP_008939.1|refseq:NP_065393.1|refseq:NP_722550.1|refseq:NP_997403.1|refseq:NP_997404.1|ensembl:ENSG00000115310(gene)|ensembl:ENST00000337526(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0014069"(postsynaptic density)|go:"GO:0021801"(cerebral cortex radial glia-guided migration)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0035441"(cell migration involved in vasculogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0042995"(cell projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:0098826"(endoplasmic reticulum tubular network membrane)|go:"GO:0120078"(cell adhesion involved in sprouting angiogenesis)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902624"(positive regulation of neutrophil migration)|go:"GO:1905523"(positive regulation of macrophage migration)|go:"GO:1905552"(positive regulation of protein localization to endoplasmic reticulum)|go:"GO:1905580"(positive regulation of ERBB3 signaling pathway)|go:"GO:1905653"(positive regulation of artery morphogenesis)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|go:"GO:2000172"(regulation of branching morphogenesis of a nerve)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001213"(negative regulation of vasculogenesis)|interpro:IPR003388(Reticulon)|mint:Q9NQC3|rcsb pdb:2G31|rcsb pdb:2JV5|reactome:R-HSA-193634|refseq:XP_005264491.1|refseq:NP_001308788.1|refseq:NP_001308789.1|refseq:NP_001308790.1|refseq:NP_001308791.1|refseq:NP_001308792.1|refseq:NP_001308833.1|refseq:XP_016860007.1|refseq:XP_016860008.1|dip:DIP-42003N|genbank_nucl_gi:24431933(identity)	-	comment:mint|function:"Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate. In contrast to DERL1, it is not involved in the degradation of MHC class I heavy chains following infection by cytomegaloviruses. May play a role in cell proliferation"	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:hoayS/Xn9+pq/C61NYRu/1aOm6s9606	rogid:uhivTNOPdC7+q81CliY0Ozu0EwA9606	rigid:Hk00AwMYIkgmN/JdzZlWfZ4dq7U	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:P00403	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-2105756|uniprotkb:Q37526|ensembl:ENSP00000354876	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:cox2_human(display_long)|uniprotkb:MT-CO2(gene name)|psi-mi:MT-CO2(display_short)|uniprotkb:COII(gene name synonym)|uniprotkb:COXII(gene name synonym)|uniprotkb:MTCO2(gene name synonym)|uniprotkb:Cytochrome c oxidase polypeptide II(gene name synonym)|uniprotkb:COX2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770166|imex:IM-28143-36	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:YP_003024029.1|ensembl:ENSG00000198712(gene)|ensembl:ENST00000361739(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0007595"(lactation)|go:"GO:0009409"(response to cold)|go:"GO:0010729"(positive regulation of hydrogen peroxide biosynthetic process)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042773"(ATP synthesis coupled electron transport)|go:"GO:0045277"(respiratory chain complex IV)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR001505("Copper centre Cu(A)")|interpro:IPR002429(Cytochrome c oxidase subunit II C-terminal)|interpro:IPR008972(Cupredoxin)|interpro:IPR011759(Cytochrome C oxidase subunit II, transmembrane region)|interpro:IPR014222(Cytochrome c oxidase, subunit II)|interpro:IPR034210|interpro:IPR036257|mint:P00403|rcsb pdb:3VRJ|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|genbank_nucl_gi:117020(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:NyMmciQe53E935KEZahz8cGPjIM9606	rigid:xxIm1iRP0RJUaE37HuUxCFcqCms	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:Q9GZP9	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-7962814|uniprotkb:Q9Y3A7|intact:MINT-3065126|ensembl:ENSP00000158771	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:derl2_human(display_long)|uniprotkb:DERL2(gene name)|psi-mi:DERL2(display_short)|uniprotkb:DER2(gene name synonym)|uniprotkb:FLANA(gene name synonym)|uniprotkb:CGI-101(orf name)|uniprotkb:SBBI53(orf name)|uniprotkb:Der1-like protein 2(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 2(gene name synonym)|uniprotkb:F-LAN-1(gene name synonym)|uniprotkb:F-LANa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770166|imex:IM-28143-36	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_001291708.1|refseq:NP_057125.2|ensembl:ENSG00000072849(gene)|ensembl:ENST00000158771(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0001967"(suckling behavior)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|genbank_nucl_gi:50400648(identity)	-	-	comment:mint|function:"Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate. In contrast to DERL1, it is not involved in the degradation of MHC class I heavy chains following infection by cytomegaloviruses. May play a role in cell proliferation"	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:hoayS/Xn9+pq/C61NYRu/1aOm6s9606	rigid:xxIm1iRP0RJUaE37HuUxCFcqCms	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:P05787	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-297852|uniprotkb:Q14099|uniprotkb:Q14716|uniprotkb:Q14717|uniprotkb:Q53GJ0|uniprotkb:Q6DHW5|uniprotkb:Q6GMY0|uniprotkb:Q6P4C7|uniprotkb:Q96J60|ensembl:ENSP00000293308|ensembl:ENSP00000447402|ensembl:ENSP00000447566|uniprotkb:A8K4H3|uniprotkb:B0AZN5|uniprotkb:F8VXB4	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:k2c8_human(display_long)|uniprotkb:Keratin-8(gene name synonym)|uniprotkb:KRT8(gene name)|psi-mi:KRT8(display_short)|uniprotkb:CYK8(gene name synonym)|uniprotkb:Cytokeratin-8(gene name synonym)|uniprotkb:Type-II keratin Kb8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770166|imex:IM-28143-36	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_001243222.1|ensembl:ENSG00000170421(gene)|ensembl:ENST00000293308(transcript)|ensembl:ENST00000546897(transcript)|ensembl:ENST00000552551(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005911"(cell-cell junction)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030018"(Z disc)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045095"(keratin filament)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051599"(response to hydrostatic pressure)|go:"GO:0051707"(response to other organism)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P05787|reactome:R-HSA-6805567|reactome:R-HSA-6809371|refseq:NP_002264.1|dip:DIP-424N|genbank_nucl_gi:90110027(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:zyV8eOjx426ehjJYK4jsizORUws9606	rigid:xxIm1iRP0RJUaE37HuUxCFcqCms	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:Q71U36	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770166|imex:IM-28143-36	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|genbank_nucl_gi:55977864(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606	rigid:xxIm1iRP0RJUaE37HuUxCFcqCms	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:P68363	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770166|imex:IM-28143-36	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328|genbank_nucl_gi:55977474(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606	rigid:xxIm1iRP0RJUaE37HuUxCFcqCms	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:P63267	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-297795|uniprotkb:P12718|uniprotkb:Q504R1|uniprotkb:Q6FI22|ensembl:ENSP00000295137|ensembl:ENSP00000386857|uniprotkb:B2R7E7|uniprotkb:D6W5H8|uniprotkb:B4E315|uniprotkb:E9PG30	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:acth_human(display_long)|uniprotkb:ACTG2(gene name)|psi-mi:ACTG2(display_short)|uniprotkb:ACTA3(gene name synonym)|uniprotkb:ACTSG(gene name synonym)|uniprotkb:Smooth muscle gamma-actin(gene name synonym)|uniprotkb:Gamma-2-actin(gene name synonym)|uniprotkb:Alpha-actin-3(gene name synonym)|uniprotkb:ACTL3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770166|imex:IM-28143-36	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0032982"(myosin filament)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0072562"(blood microparticle)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:6JAT|reactome:R-HSA-445355|go:"GO:0010628"(positive regulation of gene expression)|ensembl:ENST00000345517(transcript)|ensembl:ENST00000409624(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|ensembl:ENSG00000163017(gene)|refseq:NP_001186822.1|refseq:NP_001606.1|genbank_nucl_gi:54036679(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:tp0JsXhrGsRl5i4Wg2dyaPGUPxA9606	rigid:xxIm1iRP0RJUaE37HuUxCFcqCms	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:P63261	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-351292|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|uniprotkb:Q5U032|uniprotkb:Q96E67|uniprotkb:A8K7C2|ensembl:ENSP00000505060|ensembl:ENSP00000505193|ensembl:ENSP00000505235|ensembl:ENSP00000506126|ensembl:ENSP00000506201|ensembl:ENSP00000506253|ensembl:ENSP00000458162|ensembl:ENSP00000458435|ensembl:ENSP00000459119|ensembl:ENSP00000459124|ensembl:ENSP00000460464|ensembl:ENSP00000460660|ensembl:ENSP00000461672|ensembl:ENSP00000466346|ensembl:ENSP00000477968	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:actg_human(display_long)|uniprotkb:ACTG1(gene name)|psi-mi:ACTG1(display_short)|uniprotkb:ACTG(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770166|imex:IM-28143-36	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_001186883.1|refseq:NP_001605.1|ensembl:ENST00000570382(transcript)|ensembl:ENSG00000184009(gene)|ensembl:ENST00000571721(transcript)|ensembl:ENST00000573283(transcript)|ensembl:ENST00000575087(transcript)|ensembl:ENST00000575659(transcript)|ensembl:ENST00000575842(transcript)|ensembl:ENST00000575994(transcript)|ensembl:ENST00000576544(transcript)|ensembl:ENST00000615544(transcript)|ensembl:ENST00000679480(transcript)|ensembl:ENST00000679778(transcript)|ensembl:ENST00000680227(transcript)|ensembl:ENST00000680727(transcript)|ensembl:ENST00000681052(transcript)|ensembl:ENST00000681842(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P63261|rcsb pdb:5JLH|rcsb pdb:6CXI|rcsb pdb:6CXJ|rcsb pdb:6G2T|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-445095|reactome:R-HSA-446353|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9013418|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|genbank_nucl_gi:54036678(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY9606	rigid:xxIm1iRP0RJUaE37HuUxCFcqCms	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:P55786	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-1046129|uniprotkb:Q6P145|uniprotkb:Q9NP16|uniprotkb:Q9UEM2|ensembl:ENSP00000320324|ensembl:ENSP00000503682|uniprotkb:B7Z463	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:psa_human(display_long)|uniprotkb:NPEPPS(gene name)|psi-mi:NPEPPS(display_short)|uniprotkb:PSA(gene name synonym)|uniprotkb:Cytosol alanyl aminopeptidase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770166|imex:IM-28143-36	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_006301.3|ensembl:ENSG00000141279(gene)|ensembl:ENST00000322157(transcript)|ensembl:ENST00000677120(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042277"(peptide binding)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR024571|interpro:IPR027268|interpro:IPR034016|interpro:IPR042097|reactome:R-HSA-983168|refseq:NP_001317186.1|genbank_nucl_gi:51704228(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:gDl9SPlJhCOhA8uF4OEw+lIPh2M9606	rigid:xxIm1iRP0RJUaE37HuUxCFcqCms	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:P17858	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-487243|uniprotkb:Q96A64|uniprotkb:Q96IH4|uniprotkb:Q9BR91|ensembl:ENSP00000269848	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:pfkal_human(display_long)|uniprotkb:PFKL(gene name)|psi-mi:PFKL(display_short)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:Phosphofructo-1-kinase isozyme B(gene name synonym)|uniprotkb:6-phosphofructokinase type B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770166|imex:IM-28143-36	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_001002021.2|refseq:NP_002617.3|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0009749"(response to glucose)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070095"(fructose-6-phosphate binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070061"(fructose binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000023(Phosphofructokinase)|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR022953|interpro:IPR035966|interpro:IPR041914|mint:P17858|reactome:R-HSA-6798695|reactome:R-HSA-70171|ensembl:ENSG00000141959(gene)|ensembl:ENST00000349048(transcript)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005945"(6-phosphofructokinase complex)|genbank_nucl_gi:48762920(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:lP9/V5WcCl5rLpy4QEZnWkLCCcQ9606	rigid:xxIm1iRP0RJUaE37HuUxCFcqCms	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:P61204	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-641535|uniprotkb:P16587|uniprotkb:A8K6G8|ensembl:ENSP00000256682|ensembl:ENSP00000438510|uniprotkb:B7ZB63	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:arf3_human(display_long)|uniprotkb:ARF3(gene name)|psi-mi:ARF3(display_short)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770166|imex:IM-28143-36	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_001650.1|ensembl:ENSG00000134287(gene)|ensembl:ENST00000256682(transcript)|ensembl:ENST00000541959(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P61204|rcsb pdb:6II6|reactome:R-HSA-1660514|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:XP_005268913.1|genbank_nucl_gi:47117657(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:np09WjdbXRu9vgMbiXn9EA3ExqA9606	rigid:xxIm1iRP0RJUaE37HuUxCFcqCms	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:Q9UBE0	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-743154|ensembl:ENSP00000270225|uniprotkb:O95717|uniprotkb:Q9P020|uniprotkb:B2RDP5|uniprotkb:B3KMQ2|uniprotkb:F5GXX7|uniprotkb:G3XAK6	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:sae1_human(display_long)|uniprotkb:Ubiquitin-like 1-activating enzyme E1A(gene name synonym)|uniprotkb:SAE1(gene name)|psi-mi:SAE1(display_short)|uniprotkb:AOS1(gene name synonym)|uniprotkb:UBLE1A(gene name synonym)|uniprotkb:SUA1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770166|imex:IM-28143-36	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	ensembl:ENSG00000142230(gene)|ensembl:ENST00000270225(transcript)|go:"GO:0004839"(ubiquitin activating enzyme activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031510"(SUMO activating enzyme complex)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000011(Ubiquitin-activating enzyme, E1)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR035985|mint:Q9UBE0|rcsb pdb:1Y8Q|rcsb pdb:1Y8R|rcsb pdb:3KYC|rcsb pdb:3KYD|rcsb pdb:6CWY|rcsb pdb:6CWZ|rcsb pdb:6XOG|rcsb pdb:6XOH|rcsb pdb:6XOI|reactome:R-HSA-3065676|reactome:R-HSA-3065678|refseq:NP_005491.1|refseq:NP_001139185.1|refseq:NP_001139186.1|dip:DIP-34587N|genbank_nucl_gi:42559897(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:8Az5p8NJ5XfF1pxbyynnYrQLFN89606	rigid:xxIm1iRP0RJUaE37HuUxCFcqCms	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:P31689	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-347834|ensembl:ENSP00000369127|uniprotkb:Q5T7Q0|uniprotkb:Q86TL9	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:dnja1_human(display_long)|uniprotkb:DNAJA1(gene name)|psi-mi:DNAJA1(display_short)|uniprotkb:DNAJ2(gene name synonym)|uniprotkb:HDJ2(gene name synonym)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:HSPF4(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 4(gene name synonym)|uniprotkb:DnaJ protein homolog 2(gene name synonym)|uniprotkb:Human DnaJ protein 2(gene name synonym)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:HSDJ(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770166|imex:IM-28143-36	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	ensembl:ENSG00000086061(gene)|ensembl:ENST00000330899(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009408"(response to heat)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:1901998"(toxin transport)|go:"GO:1903748"(negative regulation of establishment of protein localization to mitochondrion)|go:"GO:1905259"(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:P31689|rcsb pdb:2LO1|rcsb pdb:2M6Y|reactome:R-HSA-3371497|rcsb pdb:6E8M|refseq:NP_001530.1|genbank_nucl_gi:422811(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:YEHeLHYaG2ON2gwuFfqt9Le1Drg9606	rigid:xxIm1iRP0RJUaE37HuUxCFcqCms	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:Q96P70	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-356319|intact:EBI-1059309|uniprotkb:Q8N1Y1|uniprotkb:Q8N3I2|uniprotkb:Q8NCG9|uniprotkb:Q96SU6|uniprotkb:Q9NW01|uniprotkb:Q9P0A8|uniprotkb:Q9ULM8|ensembl:ENSP00000354742|uniprotkb:B1ASV5	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:ipo9_human(display_long)|uniprotkb:HSPC273(orf name)|uniprotkb:IPO9(gene name)|psi-mi:IPO9(display_short)|uniprotkb:IMP9(gene name synonym)|uniprotkb:KIAA1192(gene name synonym)|uniprotkb:RANBP9(gene name synonym)|uniprotkb:Ran-binding protein 9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770166|imex:IM-28143-36	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_060555.2|ensembl:ENSG00000198700(gene)|ensembl:ENST00000361565(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042393"(histone binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|mint:Q96P70|rcsb pdb:6N1Z|genbank_nucl_gi:41688593(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:jsjQSBULeF1L2FlDcPZouMz6pJE9606	rigid:xxIm1iRP0RJUaE37HuUxCFcqCms	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:P78527	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770166|imex:IM-28143-36	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N|genbank_nucl_gi:38258929(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606	rigid:xxIm1iRP0RJUaE37HuUxCFcqCms	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:O94905	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-4400770|uniprotkb:A0JLQ1|uniprotkb:A8K5S9|uniprotkb:B4DM38|uniprotkb:D3DSW0|uniprotkb:Q6NW21|uniprotkb:Q86VS6|uniprotkb:Q86W49|ensembl:ENSP00000428112	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:erln2_human(display_long)|uniprotkb:ERLIN2(gene name)|psi-mi:ERLIN2(display_short)|uniprotkb:C8orf2(gene name synonym)|uniprotkb:SPFH2(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 2(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2(gene name synonym)|uniprotkb:UNQ2441/PRO5003/PRO9924(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770166|imex:IM-28143-36	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_001003790.1|refseq:NP_001003791.1|refseq:NP_009106.1|refseq:XP_016868489.1|refseq:XP_005273449.1|ensembl:ENSG00000147475(gene)|ensembl:ENST00000519638(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045121"(membrane raft)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O94905|reactome:R-HSA-382556|reactome:R-HSA-5655302|reactome:R-HSA-5678895|reactome:R-HSA-8853336|genbank_nucl_gi:38257366(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:Evjg3G0FFeQ499BNlJxpK6t8to89606	rigid:xxIm1iRP0RJUaE37HuUxCFcqCms	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:P22695	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-1051424|uniprotkb:Q9BQ05|uniprotkb:B3KSN4|ensembl:ENSP00000268379	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:qcr2_human(display_long)|uniprotkb:Ubiquinol-cytochrome-c reductase complex core protein 2(gene name synonym)|uniprotkb:Core protein II(gene name synonym)|uniprotkb:Complex III subunit 2(gene name synonym)|uniprotkb:UQCRC2(gene name)|psi-mi:UQCRC2(display_short)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770166|imex:IM-28143-36	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_003357.2|ensembl:ENSG00000140740(gene)|ensembl:ENST00000268379(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006508"(proteolysis)|go:"GO:0009060"(aerobic respiration)|go:"GO:0042493"|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|mint:P22695|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|genbank_nucl_gi:21903482(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:++DmwaVpqzRyxFl7mh62L4ku4P09606	rigid:xxIm1iRP0RJUaE37HuUxCFcqCms	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:P50454	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-350723|uniprotkb:P29043|uniprotkb:Q5XPB4|uniprotkb:Q6NSJ6|uniprotkb:Q8IY96|uniprotkb:Q9NP88|uniprotkb:B3KVJ3|ensembl:ENSP00000350894|ensembl:ENSP00000434412|ensembl:ENSP00000434657	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:serph_human(display_long)|uniprotkb:SERPINH1(gene name)|psi-mi:SERPINH1(display_short)|uniprotkb:CBP2(gene name synonym)|uniprotkb:Collagen-binding protein(gene name synonym)|uniprotkb:47 kDa heat shock protein(gene name synonym)|uniprotkb:Rheumatoid arthritis-related antigen RA-A47(gene name synonym)|uniprotkb:Arsenic-transactivated protein 3(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 14 protein(gene name synonym)|uniprotkb:CBP1(gene name synonym)|uniprotkb:HSP47(gene name synonym)|uniprotkb:SERPINH2(gene name synonym)|uniprotkb:PIG14(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770166|imex:IM-28143-36	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_001193943.1|refseq:NP_001226.2|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0032964"(collagen biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR033547|interpro:IPR033830|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P50454|reactome:R-HSA-1650814|ensembl:ENSG00000149257(gene)|ensembl:ENST00000358171(transcript)|ensembl:ENST00000524558(transcript)|ensembl:ENST00000533603(transcript)|go:"GO:0003433"(chondrocyte development involved in endochondral bone morphogenesis)|refseq:XP_011543629.1|genbank_nucl_gi:20141241(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:cO3NR2hb0NyOs99Sq1aODePlDR09606	rigid:xxIm1iRP0RJUaE37HuUxCFcqCms	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:P51151	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-4401353|uniprotkb:Q6ICN1|uniprotkb:A8K390|ensembl:ENSP00000420127|ensembl:ENSP00000480777	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:rab9a_human(display_long)|uniprotkb:RAB9A(gene name)|psi-mi:RAB9A(display_short)|uniprotkb:RAB9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770166|imex:IM-28143-36	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:XP_016885453.1|refseq:NP_001182257.1|refseq:NP_004242.1|dip:DIP-46409N|ensembl:ENSG00000123595(gene)|ensembl:ENST00000464506(transcript)|ensembl:ENST00000618931(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042470"(melanosome)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0052405"|go:"GO:0070062"(extracellular exosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041824|mint:P51151|rcsb pdb:1WMS|reactome:R-HSA-6811440|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9706019|genbank_nucl_gi:1710003(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:x0BjgzGEj7mPNlt2CQLkHtqQzDQ9606	rigid:xxIm1iRP0RJUaE37HuUxCFcqCms	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:P50402	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-489887|uniprotkb:Q6FI02|ensembl:ENSP00000358857|ensembl:ENSP00000507533	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:emd_human(display_long)|uniprotkb:EDMD(gene name synonym)|uniprotkb:STA(gene name synonym)|uniprotkb:EMD(gene name)|psi-mi:EMD(display_short)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770166|imex:IM-28143-36	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_000108.1|ensembl:ENSP00000358857|ensembl:ENSP00000507533|ensembl:ENSG00000102119(gene)|ensembl:ENST00000369842(transcript)|ensembl:ENST00000683627(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR011015(LEM-like fold)|interpro:IPR034989|interpro:IPR035004|mint:P50402|rcsb pdb:1JEI|rcsb pdb:2ODC|rcsb pdb:2ODG|rcsb pdb:6GHD|rcsb pdb:6RPR|rcsb pdb:7NDY|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609523|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|dip:DIP-34638N|genbank_nucl_gi:1706639(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:hqH2sFjAGwjIGtGX/rjVVFgaYsE9606	rigid:xxIm1iRP0RJUaE37HuUxCFcqCms	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:Q01813	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-359022|uniprotkb:B3KS15|uniprotkb:Q5VSR7|uniprotkb:Q5VSR8|ensembl:ENSP00000370517	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:pfkap_human(display_long)|uniprotkb:PFKP(gene name)|psi-mi:PFKP(display_short)|uniprotkb:PFKF(gene name synonym)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:Phosphofructo-1-kinase isozyme C(gene name synonym)|uniprotkb:6-phosphofructokinase type C(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770166|imex:IM-28143-36	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_002618.1|ensembl:ENSG00000067057(gene)|ensembl:ENST00000381125(transcript)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005945"(6-phosphofructokinase complex)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070095"(fructose-6-phosphate binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000023(Phosphofructokinase)|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR022953|interpro:IPR035966|interpro:IPR041914|mint:Q01813|rcsb pdb:4RH3|rcsb pdb:4U1R|rcsb pdb:4WL0|rcsb pdb:4XYJ|rcsb pdb:4XYK|rcsb pdb:4XZ2|reactome:R-HSA-70171|refseq:NP_001229268.1|dip:DIP-45850N|genbank_nucl_gi:1346355(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:GNmWbFrQsTMRdVphWG+3DK3wxaA9606	rigid:xxIm1iRP0RJUaE37HuUxCFcqCms	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:P05783	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-297888|uniprotkb:Q53G38|uniprotkb:Q5U0N8|uniprotkb:Q9BW26|ensembl:ENSP00000373487|ensembl:ENSP00000373489	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:k1c18_human(display_long)|uniprotkb:KRT18(gene name)|psi-mi:KRT18(display_short)|uniprotkb:CYK18(gene name synonym)|uniprotkb:Keratin-18(gene name synonym)|uniprotkb:PIG46(orf name)|uniprotkb:Cytokeratin-18(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 46 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770166|imex:IM-28143-36	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005912"(adherens junction)|go:"GO:0007049"(cell cycle)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009750"(response to fructose)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034451"(centriolar satellite)|go:"GO:0043000"(Golgi to plasma membrane CFTR protein transport)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045095"(keratin filament)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0072497"(mesenchymal stem cell differentiation)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1902488"(cholangiocyte apoptotic process)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR027695|interpro:IPR039008|mint:P05783|reactome:R-HSA-6805567|reactome:R-HSA-6809371|ensembl:ENSG00000111057(gene)|ensembl:ENST00000388835(transcript)|ensembl:ENST00000388837(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|refseq:NP_000215.1|refseq:NP_954657.1|dip:DIP-633N|genbank_nucl_gi:125083(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:6rtLZxuG0CSGcsCHEmkRKFVDeyo9606	rigid:xxIm1iRP0RJUaE37HuUxCFcqCms	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:P14625	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-359129|uniprotkb:Q96A97|ensembl:ENSP00000299767	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:enpl_human(display_long)|uniprotkb:HSP90B1(gene name)|psi-mi:HSP90B1(display_short)|uniprotkb:TRA1(gene name synonym)|uniprotkb:Heat shock protein 90 kDa beta member 1(gene name synonym)|uniprotkb:94 kDa glucose-regulated protein(gene name synonym)|uniprotkb:GRP94(gene name synonym)|uniprotkb:gp96 homolog(gene name synonym)|uniprotkb:Tumor rejection antigen 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770166|imex:IM-28143-36	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_003290.1|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051208"(sequestering of calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071682"(endocytic vesicle lumen)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P14625|rcsb pdb:4NH9|reactome:R-HSA-1679131|reactome:R-HSA-3000480|reactome:R-HSA-381183|reactome:R-HSA-381426|reactome:R-HSA-6785807|reactome:R-HSA-8957275|ensembl:ENSG00000166598(gene)|ensembl:ENST00000299767(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031247"(actin rod assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|dip:DIP-36060N|genbank_nucl_gi:119360(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:m5CdlplqVyMUWYe75aKDuMzztMY9606	rigid:xxIm1iRP0RJUaE37HuUxCFcqCms	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:P13073	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-1056574|uniprotkb:B2R4J2|uniprotkb:D3DUM7|uniprotkb:Q6P666|ensembl:ENSP00000253452|ensembl:ENSP00000457015|ensembl:ENSP00000457513	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:cox41_human(display_long)|uniprotkb:COX4I1(gene name)|psi-mi:COX4I1(display_short)|uniprotkb:COX4(gene name synonym)|uniprotkb:Cytochrome c oxidase subunit IV isoform 1(gene name synonym)|uniprotkb:Cytochrome c oxidase polypeptide IV(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770166|imex:IM-28143-36	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_001852.1|refseq:NP_001305726.1|refseq:NP_001305731.1|refseq:NP_001305715.1|refseq:NP_001305717.1|refseq:NP_001305723.1|ensembl:ENSG00000131143(gene)|ensembl:ENST00000253452(transcript)|ensembl:ENST00000561569(transcript)|ensembl:ENST00000562336(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0005829"(cytosol)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0007584"(response to nutrient)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004203(Cytochrome c oxidase subunit IV)|interpro:IPR013288(Cytochrome c oxidase subunit 4)|interpro:IPR036639|mint:P13073|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|genbank_nucl_gi:117086(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:7TbisLJIPPlFeZNNXqP9SciPjLw9606	rigid:xxIm1iRP0RJUaE37HuUxCFcqCms	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:P06576	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-356231|ensembl:ENSP00000262030|uniprotkb:Q14283|uniprotkb:A8K4X0|intact:EBI-2322803	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:atpb_human(display_long)|uniprotkb:ATP5F1B(gene name)|psi-mi:ATP5F1B(display_short)|uniprotkb:ATP synthase F1 subunit beta(gene name synonym)|uniprotkb:ATP5B(gene name synonym)|uniprotkb:ATPMB(gene name synonym)|uniprotkb:ATPSB(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770166|imex:IM-28143-36	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	ensembl:ENSG00000110955(gene)|ensembl:ENST00000262030(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005722(ATPase, F1 complex, beta subunit)|interpro:IPR020003|interpro:IPR024034|interpro:IPR027417|interpro:IPR036121|mint:P06576|reactome:R-HSA-1268020|reactome:R-HSA-163210|reactome:R-HSA-2151201|reactome:R-HSA-8949613|go:"GO:0070062"(extracellular exosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051453"(regulation of intracellular pH)|refseq:NP_001677.2|genbank_nucl_gi:114549(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:oLPUvG1tQkkzxzeAG6R0ZkZF+eg9606	rigid:xxIm1iRP0RJUaE37HuUxCFcqCms	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q13438	uniprotkb:Q9UBV2	intact:EBI-725454|intact:EBI-1174342|uniprotkb:A6NDD1|uniprotkb:A6NFR7|uniprotkb:A6NLB2|uniprotkb:A8K5Q9|uniprotkb:B4DPX1|uniprotkb:B4E1I6|uniprotkb:E7ENT8|uniprotkb:F8VUH2|uniprotkb:O00579|uniprotkb:Q6IBL2|uniprotkb:Q8IZ58|uniprotkb:Q9BW99|uniprotkb:B4DE28|ensembl:ENSP00000318165|uniprotkb:E7EW91|uniprotkb:G3XA88	intact:EBI-358766|uniprotkb:Q6UWT6|uniprotkb:Q9P1T9|uniprotkb:Q9UHK7|ensembl:ENSP00000337053	psi-mi:os9_human(display_long)|uniprotkb:OS9(gene name)|psi-mi:OS9(display_short)|uniprotkb:Amplified in osteosarcoma 9(gene name synonym)	psi-mi:se1l1_human(display_long)|uniprotkb:SEL1L(gene name)|psi-mi:SEL1L(display_short)|uniprotkb:TSA305(gene name synonym)|uniprotkb:UNQ128/PRO1063(orf name)|uniprotkb:Suppressor of lin-12-like protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770661|imex:IM-28143-76	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006803.1|refseq:NP_001017956.1|refseq:NP_001017957.1|refseq:NP_001017958.1|refseq:NP_001248349.1|refseq:NP_001248350.1|refseq:NP_001248351.1|refseq:NP_001248352.1|ensembl:ENSG00000135506(gene)|ensembl:ENST00000315970(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0002020"(protease binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006605"(protein targeting)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|interpro:IPR044865|rcsb pdb:3AIH|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-37493N|genbank_nucl_gi:3024310(identity)	refseq:NP_001231913.1|refseq:NP_005056.3|ensembl:ENSG00000071537(gene)|ensembl:ENST00000336735(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0050821"(protein stabilization)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|mint:Q9UBV2|reactome:R-HSA-1912420|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-46259N	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:Ntc3geE7th+rBeIp0MxuUuu/28Y9606	rogid:eufE+8nfcHK8CDl+AQ5G+3NtL+09606	rigid:h5uvYAuJTHQSgZCgpWSIhCTPvs4	false	-	s tag:?-?	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q92611	uniprotkb:Q9NZJ7	intact:EBI-1056336|uniprotkb:A8K9C8|uniprotkb:B4DXP3|ensembl:ENSP00000256497	intact:EBI-297455|ensembl:ENSP00000362730|uniprotkb:Q6PK60|uniprotkb:Q6UX45|uniprotkb:Q7L465|uniprotkb:Q9BW23|uniprotkb:Q9NZR6|uniprotkb:Q9UJZ5|uniprotkb:B2RCE3|uniprotkb:A8KAX5	psi-mi:edem1_human(display_long)|uniprotkb:EDEM1(gene name)|psi-mi:EDEM1(display_short)|uniprotkb:EDEM(gene name synonym)|uniprotkb:KIAA0212(gene name synonym)	psi-mi:mtch1_human(display_long)|uniprotkb:Presenilin-associated protein(gene name synonym)|uniprotkb:CGI-64(orf name)|uniprotkb:MTCH1(gene name)|psi-mi:MTCH1(display_short)|uniprotkb:PSAP(gene name synonym)|uniprotkb:UNQ1871/PRO4314(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770790|imex:IM-28143-96	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055489.1|ensembl:ENSG00000134109(gene)|ensembl:ENST00000256497(transcript)|go:"GO:0004571"(mannosyl-oligosaccharide 1,2-alpha-mannosidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016235"(aggresome)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036510"(trimming of terminal mannose on C branch)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0097466"(ubiquitin-dependent glycoprotein ERAD pathway)|go:"GO:1904154"(positive regulation of retrograde protein transport, ER to cytosol)|go:"GO:1904382"(mannose trimming involved in glycoprotein ERAD pathway)|interpro:IPR001382(Glycoside hydrolase, family 47)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR036026|interpro:IPR044674|mint:Q92611|reactome:R-HSA-381038|reactome:R-HSA-901032|go:"GO:0045047"(protein targeting to ER)	ensembl:ENSG00000137409(gene)|ensembl:ENST00000373627(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045161"(neuronal ion channel clustering)|interpro:IPR018108|interpro:IPR023395|mint:Q9NZJ7|refseq:NP_055156.1|refseq:NP_001258570.1|genbank_nucl_gi:7657345(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:KbPqpha4jyv6T/WPHyqQTAUjD1U9606	rogid:I0J5CxSiLB4OS6mhqwygLq389xY9606	rigid:XWmoMuy8295n77I/Z+C9K7aZIt8	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q92611	uniprotkb:Q9BSJ8	intact:EBI-1056336|uniprotkb:A8K9C8|uniprotkb:B4DXP3|ensembl:ENSP00000256497	intact:EBI-355956|ensembl:ENSP00000377612|uniprotkb:A0FGR7|uniprotkb:A8K2S2|uniprotkb:O94848|uniprotkb:Q6PJN4|uniprotkb:Q9H6J1|uniprotkb:Q9H6W2|uniprotkb:Q9Y416|intact:EBI-4399548	psi-mi:edem1_human(display_long)|uniprotkb:EDEM1(gene name)|psi-mi:EDEM1(display_short)|uniprotkb:EDEM(gene name synonym)|uniprotkb:KIAA0212(gene name synonym)	psi-mi:esyt1_human(display_long)|uniprotkb:KIAA0747(gene name synonym)|uniprotkb:MBC2(gene name synonym)|uniprotkb:ESYT1(gene name)|psi-mi:ESYT1(display_short)|uniprotkb:Membrane-bound C2 domain-containing protein(gene name synonym)|uniprotkb:FAM62A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770790|imex:IM-28143-96	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055489.1|ensembl:ENSG00000134109(gene)|ensembl:ENST00000256497(transcript)|go:"GO:0004571"(mannosyl-oligosaccharide 1,2-alpha-mannosidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016235"(aggresome)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036510"(trimming of terminal mannose on C branch)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0097466"(ubiquitin-dependent glycoprotein ERAD pathway)|go:"GO:1904154"(positive regulation of retrograde protein transport, ER to cytosol)|go:"GO:1904382"(mannose trimming involved in glycoprotein ERAD pathway)|interpro:IPR001382(Glycoside hydrolase, family 47)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR036026|interpro:IPR044674|mint:Q92611|reactome:R-HSA-381038|reactome:R-HSA-901032|go:"GO:0045047"(protein targeting to ER)	interpro:IPR037752|interpro:IPR039010|mint:Q9BSJ8|reactome:R-HSA-1660662|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9035034|interpro:IPR037749|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037733|go:"GO:0005544"(calcium-dependent phospholipid binding)|ensembl:ENSG00000139641(gene)|ensembl:ENST00000394048(transcript)|go:"GO:0005509"(calcium ion binding)|refseq:NP_001171725.1|refseq:NP_056107.1|dip:DIP-57197N|genbank_nucl_gi:74733019(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:KbPqpha4jyv6T/WPHyqQTAUjD1U9606	rogid:MYbYK3357LLH0TP1qU7CsvJenGk9606	rigid:XWmoMuy8295n77I/Z+C9K7aZIt8	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q92611	uniprotkb:P27824	intact:EBI-1056336|uniprotkb:A8K9C8|uniprotkb:B4DXP3|ensembl:ENSP00000256497	intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000421434|ensembl:ENSP00000421813|ensembl:ENSP00000424063|ensembl:ENSP00000424745|ensembl:ENSP00000491760|ensembl:ENSP00000492372|ensembl:ENSP00000492868|ensembl:ENSP00000505013|ensembl:ENSP00000505202|ensembl:ENSP00000505526|ensembl:ENSP00000505960|ensembl:ENSP00000506003|ensembl:ENSP00000506021|ensembl:ENSP00000506061|ensembl:ENSP00000506078|ensembl:ENSP00000506509|ensembl:ENSP00000506568|ensembl:ENSP00000506583|ensembl:ENSP00000247461|ensembl:ENSP00000391646|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3	psi-mi:edem1_human(display_long)|uniprotkb:EDEM1(gene name)|psi-mi:EDEM1(display_short)|uniprotkb:EDEM(gene name synonym)|uniprotkb:KIAA0212(gene name synonym)	psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770790|imex:IM-28143-96	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055489.1|ensembl:ENSG00000134109(gene)|ensembl:ENST00000256497(transcript)|go:"GO:0004571"(mannosyl-oligosaccharide 1,2-alpha-mannosidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016235"(aggresome)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036510"(trimming of terminal mannose on C branch)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0097466"(ubiquitin-dependent glycoprotein ERAD pathway)|go:"GO:1904154"(positive regulation of retrograde protein transport, ER to cytosol)|go:"GO:1904382"(mannose trimming involved in glycoprotein ERAD pathway)|interpro:IPR001382(Glycoside hydrolase, family 47)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR036026|interpro:IPR044674|mint:Q92611|reactome:R-HSA-381038|reactome:R-HSA-901032|go:"GO:0045047"(protein targeting to ER)	refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|go:"GO:0099059"(integral component of presynaptic active zone membrane)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|ensembl:ENST00000452673(transcript)|ensembl:ENST00000502296(transcript)|ensembl:ENST00000504734(transcript)|ensembl:ENST00000509563(transcript)|ensembl:ENST00000513246(transcript)|ensembl:ENST00000638425(transcript)|ensembl:ENST00000638706(transcript)|ensembl:ENST00000639938(transcript)|ensembl:ENST00000680013(transcript)|ensembl:ENST00000680042(transcript)|ensembl:ENST00000680092(transcript)|ensembl:ENST00000680618(transcript)|ensembl:ENST00000681072(transcript)|ensembl:ENST00000681168(transcript)|ensembl:ENST00000681476(transcript)|ensembl:ENST00000681674(transcript)|ensembl:ENST00000681712(transcript)|ensembl:ENST00000681733(transcript)|ensembl:ENST00000681903(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|ensembl:ENST00000247461(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0006457"(protein folding)|go:"GO:0007568"(aging)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|ensembl:ENSG00000127022(gene)|ensembl:ENSG00000283777(gene)|dip:DIP-457N|genbank_nucl_gi:543920(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:KbPqpha4jyv6T/WPHyqQTAUjD1U9606	rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606	rigid:XWmoMuy8295n77I/Z+C9K7aZIt8	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q92611	uniprotkb:Q9UHD9	intact:EBI-1056336|uniprotkb:A8K9C8|uniprotkb:B4DXP3|ensembl:ENSP00000256497	intact:EBI-947187|uniprotkb:O94798|uniprotkb:Q9H3W6|uniprotkb:Q9HAZ4|uniprotkb:Q5D027|intact:EBI-28967571|ensembl:ENSP00000345195	psi-mi:edem1_human(display_long)|uniprotkb:EDEM1(gene name)|psi-mi:EDEM1(display_short)|uniprotkb:EDEM(gene name synonym)|uniprotkb:KIAA0212(gene name synonym)	psi-mi:ubql2_human(display_long)|uniprotkb:UBQLN2(gene name)|psi-mi:UBQLN2(display_short)|uniprotkb:PLIC2(gene name synonym)|uniprotkb:HRIHFB2157(orf name)|uniprotkb:N4BP4(gene name synonym)|uniprotkb:Protein linking IAP with cytoskeleton 2(gene name synonym)|uniprotkb:Ubiquitin-like product Chap1/Dsk2(gene name synonym)|uniprotkb:DSK2 homolog(gene name synonym)|uniprotkb:Chap1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770790|imex:IM-28143-96	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055489.1|ensembl:ENSG00000134109(gene)|ensembl:ENST00000256497(transcript)|go:"GO:0004571"(mannosyl-oligosaccharide 1,2-alpha-mannosidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016235"(aggresome)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036510"(trimming of terminal mannose on C branch)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0097466"(ubiquitin-dependent glycoprotein ERAD pathway)|go:"GO:1904154"(positive regulation of retrograde protein transport, ER to cytosol)|go:"GO:1904382"(mannose trimming involved in glycoprotein ERAD pathway)|interpro:IPR001382(Glycoside hydrolase, family 47)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR036026|interpro:IPR044674|mint:Q92611|reactome:R-HSA-381038|reactome:R-HSA-901032|go:"GO:0045047"(protein targeting to ER)	ensembl:ENSP00000345195|refseq:NP_038472.2|dip:DIP-42116N|ensembl:ENSG00000188021(gene)|ensembl:ENST00000338222(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:1900186"(negative regulation of clathrin-dependent endocytosis)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1904021"(negative regulation of G protein-coupled receptor internalization)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028430|interpro:IPR029071|mint:Q9UHD9|rcsb pdb:1J8C|rcsb pdb:2NBV|rcsb pdb:6MUN|reactome:R-HSA-8856825|genbank_nucl_gi:124056593(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:KbPqpha4jyv6T/WPHyqQTAUjD1U9606	rogid:tElcz7gHFkKFVDTz3PXeNcaBP7U9606	rigid:XWmoMuy8295n77I/Z+C9K7aZIt8	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9P2K2	uniprotkb:Q8IWF2	intact:EBI-11126467|uniprotkb:Q9H9W7|uniprotkb:A7E260|uniprotkb:A7MD07|uniprotkb:B9EH67|uniprotkb:A5PKW9|ensembl:ENSP00000281741	intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401	psi-mi:txd16_human(display_long)|uniprotkb:TXNDC16(gene name)|psi-mi:TXNDC16(display_short)|uniprotkb:KIAA1344(gene name synonym)|uniprotkb:ERP90(gene name synonym)	psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770919|imex:IM-28143-60	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153519.1|refseq:NP_065835.2|ensembl:ENSG00000087301(gene)|ensembl:ENST00000281741(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR040090	refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N|genbank_nucl_gi:74759632(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:zzfV8NEefGI6L0ra5Z/bEg3WfEU9606	rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606	rigid:etwnLFcj5ejB28xqTES5aRCkOo8	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9P2K2	uniprotkb:P49736	intact:EBI-11126467|uniprotkb:Q9H9W7|uniprotkb:A7E260|uniprotkb:A7MD07|uniprotkb:B9EH67|uniprotkb:A5PKW9|ensembl:ENSP00000281741	intact:EBI-374819|uniprotkb:Q14577|uniprotkb:Q15023|uniprotkb:Q8N2V1|uniprotkb:Q969W7|uniprotkb:Q96AE1|uniprotkb:Q9BRM7|ensembl:ENSP00000265056	psi-mi:txd16_human(display_long)|uniprotkb:TXNDC16(gene name)|psi-mi:TXNDC16(display_short)|uniprotkb:KIAA1344(gene name synonym)|uniprotkb:ERP90(gene name synonym)	psi-mi:mcm2_human(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:BM28(gene name synonym)|uniprotkb:CDCL1(gene name synonym)|uniprotkb:KIAA0030(gene name synonym)|uniprotkb:Minichromosome maintenance protein 2 homolog(gene name synonym)|uniprotkb:Nuclear protein BM28(gene name synonym)|uniprotkb:CCNL1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770919|imex:IM-28143-60	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153519.1|refseq:NP_065835.2|ensembl:ENSG00000087301(gene)|ensembl:ENST00000281741(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR040090	ensembl:ENSG00000073111(gene)|ensembl:ENST00000265056(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006915"(apoptotic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0042393"(histone binding)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090102"(cochlea development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P49736|rcsb pdb:4UUZ|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5JA4|rcsb pdb:6XTX|rcsb pdb:6XTY|rcsb pdb:6YA7|rcsb pdb:7CIZ|rcsb pdb:7CJ0|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|refseq:NP_004517.2|dip:DIP-31732N|genbank_nucl_gi:41019490(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:zzfV8NEefGI6L0ra5Z/bEg3WfEU9606	rogid:Jt9ODNyJBwtwQ0pb/+X46vtHfE09606	rigid:etwnLFcj5ejB28xqTES5aRCkOo8	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9P2K2	uniprotkb:P45880	intact:EBI-11126467|uniprotkb:Q9H9W7|uniprotkb:A7E260|uniprotkb:A7MD07|uniprotkb:B9EH67|uniprotkb:A5PKW9|ensembl:ENSP00000281741	intact:EBI-354022|ensembl:ENSP00000361686|ensembl:ENSP00000443092|uniprotkb:Q5VWK1|uniprotkb:Q5VWK3|uniprotkb:Q6IB40|uniprotkb:Q7L3J5|uniprotkb:Q9BWK8|uniprotkb:Q9Y5I6	psi-mi:txd16_human(display_long)|uniprotkb:TXNDC16(gene name)|psi-mi:TXNDC16(display_short)|uniprotkb:KIAA1344(gene name synonym)|uniprotkb:ERP90(gene name synonym)	psi-mi:vdac2_human(display_long)|uniprotkb:VDAC2(gene name)|psi-mi:VDAC2(display_short)|uniprotkb:Outer mitochondrial membrane protein porin 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770919|imex:IM-28143-60	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153519.1|refseq:NP_065835.2|ensembl:ENSG00000087301(gene)|ensembl:ENST00000281741(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR040090	ensembl:ENSG00000165637(gene)|ensembl:ENST00000332211(transcript)|ensembl:ENST00000543351(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006820"(anion transport)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031966"(mitochondrial membrane)|refseq:NP_001171712.1|refseq:NP_001171752.1|refseq:NP_003366.2|refseq:NP_001311017.1|go:"GO:0032272"(negative regulation of protein polymerization)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046930"(pore complex)|go:"GO:0097001"(ceramide binding)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030277|mint:P45880|reactome:R-HSA-5689880|reactome:R-HSA-8949215|genbank_nucl_gi:169164151(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:zzfV8NEefGI6L0ra5Z/bEg3WfEU9606	rogid:seQxCd19Z2HmpXcwb48osAuuafA9606	rigid:etwnLFcj5ejB28xqTES5aRCkOo8	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9P2K2	uniprotkb:P21333	intact:EBI-11126467|uniprotkb:Q9H9W7|uniprotkb:A7E260|uniprotkb:A7MD07|uniprotkb:B9EH67|uniprotkb:A5PKW9|ensembl:ENSP00000281741	intact:EBI-350432|uniprotkb:Q8NF52|intact:EBI-1103234|ensembl:ENSP00000358866|uniprotkb:Q5HY53|uniprotkb:Q5HY55|uniprotkb:E9KL45	psi-mi:txd16_human(display_long)|uniprotkb:TXNDC16(gene name)|psi-mi:TXNDC16(display_short)|uniprotkb:KIAA1344(gene name synonym)|uniprotkb:ERP90(gene name synonym)	psi-mi:flna_human(display_long)|uniprotkb:FLNA(gene name)|psi-mi:FLNA(display_short)|uniprotkb:FLN(gene name synonym)|uniprotkb:FLN1(gene name synonym)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770919|imex:IM-28143-60	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153519.1|refseq:NP_065835.2|ensembl:ENSG00000087301(gene)|ensembl:ENST00000281741(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR040090	go:"GO:0007195"(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:"GO:1902396"(protein localization to bicellular tight junction)|refseq:NP_001104026.1|refseq:NP_001447.2|ensembl:ENSG00000196924(gene)|ensembl:ENST00000369850(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097368"(establishment of Sertoli cell barrier)|go:"GO:0097440"(apical dendrite)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:0046332"(SMAD binding)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0019900"(kinase binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031523"(Myb complex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045296"(cadherin binding)|reactome:R-HSA-114608|reactome:R-HSA-430116|reactome:R-HSA-446353|reactome:R-HSA-5627123|reactome:R-HSA-8983711|rcsb pdb:6EW1|go:"GO:1905031"(regulation of membrane repolarization during cardiac muscle cell action potential)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:P21333|rcsb pdb:2AAV|rcsb pdb:2BP3|rcsb pdb:2BRQ|rcsb pdb:2J3S|rcsb pdb:2JF1|rcsb pdb:2K3T|rcsb pdb:2K7P|rcsb pdb:2K7Q|rcsb pdb:2MTP|rcsb pdb:2W0P|rcsb pdb:2WFN|rcsb pdb:3CNK|rcsb pdb:3HOC|rcsb pdb:3HOP|rcsb pdb:3HOR|rcsb pdb:3ISW|rcsb pdb:3RGH|rcsb pdb:4M9P|rcsb pdb:4P3W|rcsb pdb:5XR1|rcsb pdb:6D8C|go:"GO:1905000"(regulation of membrane repolarization during atrial cardiac muscle cell action potential)|dip:DIP-1136N|genbank_nucl_gi:116063573(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:zzfV8NEefGI6L0ra5Z/bEg3WfEU9606	rogid:ZxGK5OSMy8cNsyt7Ax2KXb8bn9M9606	rigid:etwnLFcj5ejB28xqTES5aRCkOo8	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N4V1	uniprotkb:Q9NPA0	intact:EBI-6163737|ensembl:ENSP00000306220|ensembl:ENSP00000505226|uniprotkb:B2R625|uniprotkb:B4DIY3|uniprotkb:D3DWG7|uniprotkb:Q5JPP7	intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5	psi-mi:emc5_human(display_long)|uniprotkb:MMGT1(gene name)|psi-mi:MMGT1(display_short)|uniprotkb:TMEM32(gene name synonym)|uniprotkb:Transmembrane protein 32(gene name synonym)|uniprotkb:EMC5(gene name synonym)|uniprotkb:Membrane magnesium transporter 1(gene name synonym)	psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770937|imex:IM-28143-78	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-5223345|ensembl:ENSG00000169446(gene)|ensembl:ENST00000305963(transcript)|ensembl:ENST00000679621(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|refseq:NP_775741.1|refseq:NP_001316929.1	ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1|genbank_nucl_gi:74752878(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:Kq+VEYt+fwoOsEfcgZ1K1vkFFN49606	rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606	rigid:sIlfff7CNfyFyIFsCaqNn22U/CE	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N4V1	uniprotkb:Q8N766	intact:EBI-6163737|ensembl:ENSP00000306220|ensembl:ENSP00000505226|uniprotkb:B2R625|uniprotkb:B4DIY3|uniprotkb:D3DWG7|uniprotkb:Q5JPP7	intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62	psi-mi:emc5_human(display_long)|uniprotkb:MMGT1(gene name)|psi-mi:MMGT1(display_short)|uniprotkb:TMEM32(gene name synonym)|uniprotkb:Transmembrane protein 32(gene name synonym)|uniprotkb:EMC5(gene name synonym)|uniprotkb:Membrane magnesium transporter 1(gene name synonym)	psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770937|imex:IM-28143-78	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-5223345|ensembl:ENSG00000169446(gene)|ensembl:ENST00000305963(transcript)|ensembl:ENST00000679621(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|refseq:NP_775741.1|refseq:NP_001316929.1	go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1|genbank_nucl_gi:74751081(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:Kq+VEYt+fwoOsEfcgZ1K1vkFFN49606	rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606	rigid:sIlfff7CNfyFyIFsCaqNn22U/CE	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N4V1	uniprotkb:Q9BV81	intact:EBI-6163737|ensembl:ENSP00000306220|ensembl:ENSP00000505226|uniprotkb:B2R625|uniprotkb:B4DIY3|uniprotkb:D3DWG7|uniprotkb:Q5JPP7	intact:EBI-2820492|ensembl:ENSP00000248378|ensembl:ENSP00000380322	psi-mi:emc5_human(display_long)|uniprotkb:MMGT1(gene name)|psi-mi:MMGT1(display_short)|uniprotkb:TMEM32(gene name synonym)|uniprotkb:Transmembrane protein 32(gene name synonym)|uniprotkb:EMC5(gene name synonym)|uniprotkb:Membrane magnesium transporter 1(gene name synonym)	psi-mi:emc6_human(display_long)|uniprotkb:EMC6(gene name)|psi-mi:EMC6(display_short)|uniprotkb:TMEM93(gene name synonym)|uniprotkb:Transmembrane protein 93(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770937|imex:IM-28143-78	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-5223345|ensembl:ENSG00000169446(gene)|ensembl:ENST00000305963(transcript)|ensembl:ENST00000679621(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|refseq:NP_775741.1|refseq:NP_001316929.1	refseq:NP_001014764.1|refseq:NP_112588.1|ensembl:ENSG00000127774(gene)|ensembl:ENST00000248378(transcript)|ensembl:ENST00000397133(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0097631"(integral component of omegasome membrane)|interpro:IPR008504(Protein of unknown function DUF786)|interpro:IPR029008|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|go:"GO:0072546"(EMC complex)|genbank_nucl_gi:74733294(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:Kq+VEYt+fwoOsEfcgZ1K1vkFFN49606	rogid:GPnTCJqAA2eIiiP17pgtIhGnpsA9606	rigid:sIlfff7CNfyFyIFsCaqNn22U/CE	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N4V1	uniprotkb:Q5UCC4	intact:EBI-6163737|ensembl:ENSP00000306220|ensembl:ENSP00000505226|uniprotkb:B2R625|uniprotkb:B4DIY3|uniprotkb:D3DWG7|uniprotkb:Q5JPP7	intact:EBI-11284388|uniprotkb:Q5UCC6|uniprotkb:Q69YT5|uniprotkb:Q6UWP3|uniprotkb:Q86YL4|uniprotkb:Q8N541|ensembl:ENSP00000334037	psi-mi:emc5_human(display_long)|uniprotkb:MMGT1(gene name)|psi-mi:MMGT1(display_short)|uniprotkb:TMEM32(gene name synonym)|uniprotkb:Transmembrane protein 32(gene name synonym)|uniprotkb:EMC5(gene name synonym)|uniprotkb:Membrane magnesium transporter 1(gene name synonym)	psi-mi:emc10_human(display_long)|uniprotkb:EMC10(gene name)|psi-mi:EMC10(display_short)|uniprotkb:C19orf63(gene name synonym)|uniprotkb:Hematopoietic signal peptide-containing membrane domain-containing protein 1(gene name synonym)|uniprotkb:INM02(gene name synonym)|uniprotkb:UNQ764/PRO1556(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770937|imex:IM-28143-78	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-5223345|ensembl:ENSG00000169446(gene)|ensembl:ENST00000305963(transcript)|ensembl:ENST00000679621(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|refseq:NP_775741.1|refseq:NP_001316929.1	refseq:NP_778233.4|refseq:NP_996261.1|ensembl:ENSG00000161671(gene)|ensembl:ENST00000334976(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005576"(extracellular region)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR029615|mint:Q5UCC4|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|genbank_nucl_gi:74708213(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:Kq+VEYt+fwoOsEfcgZ1K1vkFFN49606	rogid:NEJjkw5uEJnzNUW7MkZIm/ELpA89606	rigid:sIlfff7CNfyFyIFsCaqNn22U/CE	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N4V1	uniprotkb:Q9P0I2	intact:EBI-6163737|ensembl:ENSP00000306220|ensembl:ENSP00000505226|uniprotkb:B2R625|uniprotkb:B4DIY3|uniprotkb:D3DWG7|uniprotkb:Q5JPP7	intact:EBI-1054670|uniprotkb:Q53GH8|uniprotkb:Q6ZMC2|uniprotkb:B2R4Z9|ensembl:ENSP00000245046	psi-mi:emc5_human(display_long)|uniprotkb:MMGT1(gene name)|psi-mi:MMGT1(display_short)|uniprotkb:TMEM32(gene name synonym)|uniprotkb:Transmembrane protein 32(gene name synonym)|uniprotkb:EMC5(gene name synonym)|uniprotkb:Membrane magnesium transporter 1(gene name synonym)	psi-mi:emc3_human(display_long)|uniprotkb:EMC3(gene name)|psi-mi:EMC3(display_short)|uniprotkb:TMEM111(gene name synonym)|uniprotkb:Transmembrane protein 111(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770937|imex:IM-28143-78	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-5223345|ensembl:ENSG00000169446(gene)|ensembl:ENST00000305963(transcript)|ensembl:ENST00000679621(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|refseq:NP_775741.1|refseq:NP_001316929.1	refseq:NP_060917.1|ensembl:ENSG00000125037(gene)|ensembl:ENST00000245046(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008568(Protein of unknown function DUF850, transmembrane eukaryotic)|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-8980692|genbank_nucl_gi:71153383(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:Kq+VEYt+fwoOsEfcgZ1K1vkFFN49606	rogid:VbIl0nFhcDMIPTxmBclaIMtbVU09606	rigid:sIlfff7CNfyFyIFsCaqNn22U/CE	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N4V1	uniprotkb:Q15006	intact:EBI-6163737|ensembl:ENSP00000306220|ensembl:ENSP00000505226|uniprotkb:B2R625|uniprotkb:B4DIY3|uniprotkb:D3DWG7|uniprotkb:Q5JPP7	intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853	psi-mi:emc5_human(display_long)|uniprotkb:MMGT1(gene name)|psi-mi:MMGT1(display_short)|uniprotkb:TMEM32(gene name synonym)|uniprotkb:Transmembrane protein 32(gene name synonym)|uniprotkb:EMC5(gene name synonym)|uniprotkb:Membrane magnesium transporter 1(gene name synonym)	psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770937|imex:IM-28143-78	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-5223345|ensembl:ENSG00000169446(gene)|ensembl:ENST00000305963(transcript)|ensembl:ENST00000679621(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|refseq:NP_775741.1|refseq:NP_001316929.1	refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|genbank_nucl_gi:3183217(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:Kq+VEYt+fwoOsEfcgZ1K1vkFFN49606	rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606	rigid:sIlfff7CNfyFyIFsCaqNn22U/CE	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N4V1	uniprotkb:O43402	intact:EBI-6163737|ensembl:ENSP00000306220|ensembl:ENSP00000505226|uniprotkb:B2R625|uniprotkb:B4DIY3|uniprotkb:D3DWG7|uniprotkb:Q5JPP7	intact:EBI-741841|ensembl:ENSP00000253457|uniprotkb:C9JB21	psi-mi:emc5_human(display_long)|uniprotkb:MMGT1(gene name)|psi-mi:MMGT1(display_short)|uniprotkb:TMEM32(gene name synonym)|uniprotkb:Transmembrane protein 32(gene name synonym)|uniprotkb:EMC5(gene name synonym)|uniprotkb:Membrane magnesium transporter 1(gene name synonym)	psi-mi:emc8_human(display_long)|uniprotkb:EMC8(gene name)|psi-mi:EMC8(display_short)|uniprotkb:C16orf2(gene name synonym)|uniprotkb:C16orf4(gene name synonym)|uniprotkb:COX4AL(gene name synonym)|uniprotkb:COX4NB(gene name synonym)|uniprotkb:FAM158B(gene name synonym)|uniprotkb:NOC4(gene name synonym)|uniprotkb:Neighbor of COX4(gene name synonym)|uniprotkb:Protein FAM158B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770937|imex:IM-28143-78	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-5223345|ensembl:ENSG00000169446(gene)|ensembl:ENST00000305963(transcript)|ensembl:ENST00000679621(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|refseq:NP_775741.1|refseq:NP_001316929.1	refseq:NP_006058.1|ensembl:ENSG00000131148(gene)|ensembl:ENST00000253457(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6WW7|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_001135760.1|genbank_nucl_gi:18202040(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:Kq+VEYt+fwoOsEfcgZ1K1vkFFN49606	rogid:cGQFR1ZU2L/KgikqLELVUzplhTU9606	rigid:sIlfff7CNfyFyIFsCaqNn22U/CE	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N4V1	uniprotkb:Q9Y3B6	intact:EBI-6163737|ensembl:ENSP00000306220|ensembl:ENSP00000505226|uniprotkb:B2R625|uniprotkb:B4DIY3|uniprotkb:D3DWG7|uniprotkb:Q5JPP7	intact:EBI-748366|uniprotkb:Q9BUM3|uniprotkb:D3DS60|ensembl:ENSP00000216799|ensembl:ENSP00000403210|ensembl:ENSP00000494976|ensembl:ENSP00000495623	psi-mi:emc5_human(display_long)|uniprotkb:MMGT1(gene name)|psi-mi:MMGT1(display_short)|uniprotkb:TMEM32(gene name synonym)|uniprotkb:Transmembrane protein 32(gene name synonym)|uniprotkb:EMC5(gene name synonym)|uniprotkb:Membrane magnesium transporter 1(gene name synonym)	psi-mi:emc9_human(display_long)|uniprotkb:EMC9(gene name)|psi-mi:EMC9(display_short)|uniprotkb:C14orf122(gene name synonym)|uniprotkb:FAM158A(gene name synonym)|uniprotkb:Protein FAM158A(gene name synonym)|uniprotkb:CGI-112(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770937|imex:IM-28143-78	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-5223345|ensembl:ENSG00000169446(gene)|ensembl:ENST00000305963(transcript)|ensembl:ENST00000679621(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|refseq:NP_775741.1|refseq:NP_001316929.1	refseq:NP_057133.2|refseq:XP_005267778.1|ensembl:ENSG00000100908(gene)|ensembl:ENSG00000285377(gene)|ensembl:ENST00000216799(transcript)|ensembl:ENST00000419198(transcript)|ensembl:ENST00000642147(transcript)|ensembl:ENST00000646772(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6Y4L|rcsb pdb:6Z3W|genbank_nucl_gi:116241305(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:Kq+VEYt+fwoOsEfcgZ1K1vkFFN49606	rogid:ZMbNxmOKb2r2KzWdB5JF/kGPSaU9606	rigid:sIlfff7CNfyFyIFsCaqNn22U/CE	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N4V1	uniprotkb:Q5J8M3	intact:EBI-6163737|ensembl:ENSP00000306220|ensembl:ENSP00000505226|uniprotkb:B2R625|uniprotkb:B4DIY3|uniprotkb:D3DWG7|uniprotkb:Q5JPP7	intact:EBI-2814031|uniprotkb:Q9P0T9|uniprotkb:Q96KX9|uniprotkb:B4DJQ4|uniprotkb:Q9BUI5|uniprotkb:A8K3A9|ensembl:ENSP00000267750	psi-mi:emc5_human(display_long)|uniprotkb:MMGT1(gene name)|psi-mi:MMGT1(display_short)|uniprotkb:TMEM32(gene name synonym)|uniprotkb:Transmembrane protein 32(gene name synonym)|uniprotkb:EMC5(gene name synonym)|uniprotkb:Membrane magnesium transporter 1(gene name synonym)	psi-mi:emc4_human(display_long)|uniprotkb:EMC4(gene name)|psi-mi:EMC4(display_short)|uniprotkb:Cell proliferation-inducing gene 17 protein(gene name synonym)|uniprotkb:TMEM85(gene name synonym)|uniprotkb:Transmembrane protein 85(gene name synonym)|uniprotkb:HSPC184(orf name)|uniprotkb:PIG17(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770937|imex:IM-28143-78	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-5223345|ensembl:ENSG00000169446(gene)|ensembl:ENST00000305963(transcript)|ensembl:ENST00000679621(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|refseq:NP_775741.1|refseq:NP_001316929.1	refseq:NP_001273349.1|refseq:NP_057538.1|ensembl:ENSG00000128463(gene)|ensembl:ENST00000267750(transcript)|go:"GO:0006915"(apoptotic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR009445(Protein of unknown function DUF1077)|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|go:"GO:0016021"(integral component of membrane)|genbank_nucl_gi:115502869(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:Kq+VEYt+fwoOsEfcgZ1K1vkFFN49606	rogid:b6qUbq3mJhmXTtZFctD6xd4E1jQ9606	rigid:sIlfff7CNfyFyIFsCaqNn22U/CE	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96IV0	uniprotkb:P54727	intact:EBI-6165879|ensembl:ENSP00000280700|uniprotkb:B4DJE9|uniprotkb:Q59FB1|uniprotkb:Q6PJD8|uniprotkb:Q9BVR8|uniprotkb:Q9NR70	intact:EBI-954531|uniprotkb:Q8WUB0|uniprotkb:B3KWK8|ensembl:ENSP00000350708|uniprotkb:G5E9P0|uniprotkb:Q7Z5K8	psi-mi:ngly1_human(display_long)|uniprotkb:NGLY1(gene name)|psi-mi:NGLY1(display_short)|uniprotkb:N-glycanase 1(gene name synonym)|uniprotkb:PNG1(gene name synonym)|uniprotkb:"Peptide:N-glycanase"(gene name synonym)	psi-mi:rd23b_human(display_long)|uniprotkb:XP-C repair-complementing complex 58 kDa protein(gene name synonym)|uniprotkb:RAD23B(gene name)|psi-mi:RAD23B(display_short)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770970|imex:IM-28143-42	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000151092(gene)|ensembl:ENST00000280700(transcript)|go:"GO:0000224"("peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006517"(protein deglycosylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|interpro:IPR002931(Transglutaminase-like)|interpro:IPR006588(Protein of unknown function PAW)|interpro:IPR008979(Galactose-binding like)|interpro:IPR018997|interpro:IPR036339|interpro:IPR038680|interpro:IPR038765|mint:Q96IV0|rcsb pdb:2CCQ|rcsb pdb:2CM0|reactome:R-HSA-532668|refseq:NP_001138767.1|refseq:NP_060767.2|refseq:NP_001138765.1|refseq:NP_001138766.1	refseq:NP_002865.1|refseq:NP_001231653.1|ensembl:ENSG00000119318(gene)|ensembl:ENST00000358015(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR036353|interpro:IPR041811|mint:P54727|rcsb pdb:1P1A|rcsb pdb:1PVE|rcsb pdb:1UEL|reactome:R-HSA-532668|reactome:R-HSA-5689877|reactome:R-HSA-5696394|reactome:R-HSA-5696395|interpro:IPR029071|dip:DIP-39944N|genbank_nucl_gi:1709985(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:CujOKLkvqxGmWpFvJM3B894PHqc9606	rogid:msyh4+G2TzDW+xgGjixPKWWrjRE9606	rigid:omJvXp2haIS5uqnslUEa8mMoVJo	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWF2	uniprotkb:Q96DZ1	intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401	intact:EBI-1023677|uniprotkb:O95901|uniprotkb:Q6UWN7|uniprotkb:Q9NUY7|uniprotkb:Q9UQL4|uniprotkb:B2RDB4|ensembl:ENSP00000185150|uniprotkb:B5MC72	psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym)	psi-mi:erlec_human(display_long)|uniprotkb:ER lectin(gene name synonym)|uniprotkb:ERLEC1(gene name)|psi-mi:ERLEC1(display_short)|uniprotkb:XTP3TPB(gene name synonym)|uniprotkb:UNQ1878/PRO4321(orf name)|uniprotkb:C2orf30(gene name synonym)|uniprotkb:XTP3-transactivated gene B protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770736|imex:IM-28143-58	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N	refseq:NP_001120870.1|refseq:NP_056516.2|ensembl:ENSG00000068912(gene)|ensembl:ENST00000185150(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR044865|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|refseq:NP_001120869.1|genbank_nucl_gi:74731510(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606	rogid:eBOyI1TfCgExBrXLxSwlUZ05NXs9606	rigid:JlcAakjTQyGVKzQW+lhRzuumwC0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWF2	uniprotkb:Q9UBV2	intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401	intact:EBI-358766|uniprotkb:Q6UWT6|uniprotkb:Q9P1T9|uniprotkb:Q9UHK7|ensembl:ENSP00000337053	psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym)	psi-mi:se1l1_human(display_long)|uniprotkb:SEL1L(gene name)|psi-mi:SEL1L(display_short)|uniprotkb:TSA305(gene name synonym)|uniprotkb:UNQ128/PRO1063(orf name)|uniprotkb:Suppressor of lin-12-like protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770736|imex:IM-28143-58	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N	refseq:NP_001231913.1|refseq:NP_005056.3|ensembl:ENSG00000071537(gene)|ensembl:ENST00000336735(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0050821"(protein stabilization)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|mint:Q9UBV2|reactome:R-HSA-1912420|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-46259N|genbank_nucl_gi:62512184(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606	rogid:eufE+8nfcHK8CDl+AQ5G+3NtL+09606	rigid:JlcAakjTQyGVKzQW+lhRzuumwC0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWF2	uniprotkb:P68133	intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401	intact:EBI-367510|uniprotkb:P02568|uniprotkb:P99020|ensembl:ENSP00000355645|uniprotkb:Q5T8M9	psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym)	psi-mi:acts_human(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770736|imex:IM-28143-58	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N	ensembl:ENSG00000143632(gene)|ensembl:ENST00000366684(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017022"(myosin binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0043531"(ADP binding)|go:"GO:0044297"(cell body)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072562"(blood microparticle)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68133|reactome:R-HSA-390522|go:"GO:0001725"(stress fiber)|refseq:NP_001091.1|genbank_nucl_gi:61218043(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606	rogid:2vZu8ElmMe+6GjKBliCAatNGZR49606	rigid:JlcAakjTQyGVKzQW+lhRzuumwC0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWF2	uniprotkb:Q9NUP9	intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401	intact:EBI-1171517|ensembl:ENSP00000278193	psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym)	psi-mi:lin7c_human(display_long)|uniprotkb:Mammalian lin-seven protein 3(gene name synonym)|uniprotkb:Vertebrate lin-7 homolog 3(gene name synonym)|uniprotkb:LIN7C(gene name)|psi-mi:LIN7C(display_short)|uniprotkb:MALS3(gene name synonym)|uniprotkb:VELI3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770736|imex:IM-28143-58	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N	refseq:NP_060832.1|ensembl:ENSG00000148943(gene)|ensembl:ENST00000278193(transcript)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006887"(exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0098793"(presynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR017365(Lin-7 homologue)|interpro:IPR036034|interpro:IPR036892|mint:Q9NUP9|rcsb pdb:3LRA|reactome:R-HSA-212676|reactome:R-HSA-6794361|reactome:R-HSA-9609736|genbank_nucl_gi:59798474(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606	rogid:F2rasaJ64Olc9qScN79LJRqsUEE9606	rigid:JlcAakjTQyGVKzQW+lhRzuumwC0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWF2	uniprotkb:P27824	intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401	intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000421434|ensembl:ENSP00000421813|ensembl:ENSP00000424063|ensembl:ENSP00000424745|ensembl:ENSP00000491760|ensembl:ENSP00000492372|ensembl:ENSP00000492868|ensembl:ENSP00000505013|ensembl:ENSP00000505202|ensembl:ENSP00000505526|ensembl:ENSP00000505960|ensembl:ENSP00000506003|ensembl:ENSP00000506021|ensembl:ENSP00000506061|ensembl:ENSP00000506078|ensembl:ENSP00000506509|ensembl:ENSP00000506568|ensembl:ENSP00000506583|ensembl:ENSP00000247461|ensembl:ENSP00000391646|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3	psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym)	psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770736|imex:IM-28143-58	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N	refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|go:"GO:0099059"(integral component of presynaptic active zone membrane)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|ensembl:ENST00000452673(transcript)|ensembl:ENST00000502296(transcript)|ensembl:ENST00000504734(transcript)|ensembl:ENST00000509563(transcript)|ensembl:ENST00000513246(transcript)|ensembl:ENST00000638425(transcript)|ensembl:ENST00000638706(transcript)|ensembl:ENST00000639938(transcript)|ensembl:ENST00000680013(transcript)|ensembl:ENST00000680042(transcript)|ensembl:ENST00000680092(transcript)|ensembl:ENST00000680618(transcript)|ensembl:ENST00000681072(transcript)|ensembl:ENST00000681168(transcript)|ensembl:ENST00000681476(transcript)|ensembl:ENST00000681674(transcript)|ensembl:ENST00000681712(transcript)|ensembl:ENST00000681733(transcript)|ensembl:ENST00000681903(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|ensembl:ENST00000247461(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0006457"(protein folding)|go:"GO:0007568"(aging)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|ensembl:ENSG00000127022(gene)|ensembl:ENSG00000283777(gene)|dip:DIP-457N|genbank_nucl_gi:543920(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606	rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606	rigid:JlcAakjTQyGVKzQW+lhRzuumwC0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWF2	uniprotkb:P63267	intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401	intact:EBI-297795|uniprotkb:P12718|uniprotkb:Q504R1|uniprotkb:Q6FI22|ensembl:ENSP00000295137|ensembl:ENSP00000386857|uniprotkb:B2R7E7|uniprotkb:D6W5H8|uniprotkb:B4E315|uniprotkb:E9PG30	psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym)	psi-mi:acth_human(display_long)|uniprotkb:ACTG2(gene name)|psi-mi:ACTG2(display_short)|uniprotkb:ACTA3(gene name synonym)|uniprotkb:ACTSG(gene name synonym)|uniprotkb:Smooth muscle gamma-actin(gene name synonym)|uniprotkb:Gamma-2-actin(gene name synonym)|uniprotkb:Alpha-actin-3(gene name synonym)|uniprotkb:ACTL3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770736|imex:IM-28143-58	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N	go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0032982"(myosin filament)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0072562"(blood microparticle)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:6JAT|reactome:R-HSA-445355|go:"GO:0010628"(positive regulation of gene expression)|ensembl:ENST00000345517(transcript)|ensembl:ENST00000409624(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|ensembl:ENSG00000163017(gene)|refseq:NP_001186822.1|refseq:NP_001606.1|genbank_nucl_gi:54036679(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606	rogid:tp0JsXhrGsRl5i4Wg2dyaPGUPxA9606	rigid:JlcAakjTQyGVKzQW+lhRzuumwC0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWF2	uniprotkb:Q9UBX3	intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401	intact:EBI-750394|uniprotkb:Q96BA1|uniprotkb:Q96IP1|uniprotkb:Q542Z3|ensembl:ENSP00000345580	psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym)	psi-mi:dic_human(display_long)|uniprotkb:Solute carrier family 25 member 10(gene name synonym)|uniprotkb:SLC25A10(gene name)|psi-mi:SLC25A10(display_short)|uniprotkb:DIC(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770736|imex:IM-28143-58	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N	refseq:NP_036272.2|refseq:NP_001257817.1|refseq:NP_001257882.1|go:"GO:0015131"(oxaloacetate transmembrane transporter activity)|go:"GO:0015140"(malate transmembrane transporter activity)|go:"GO:0015141"(succinate transmembrane transporter activity)|go:"GO:0015297"(antiporter activity)|go:"GO:0015709"(thiosulfate transport)|go:"GO:0015729"(oxaloacetate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0070221"("sulfide oxidation, using sulfide:quinone oxidoreductase")|go:"GO:0071422"(succinate transmembrane transport)|ensembl:ENSG00000183048(gene)|ensembl:ENST00000350690(transcript)|go:"GO:0005310"(dicarboxylic acid transmembrane transporter activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006811"(ion transport)|go:"GO:0006835"(dicarboxylic acid transport)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0008272"(sulfate transport)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015117"(thiosulfate transmembrane transporter activity)|reactome:R-HSA-70263|go:"GO:0071423"(malate transmembrane transport)|interpro:IPR002030(Mitochondrial brown fat uncoupling protein)|interpro:IPR018108|interpro:IPR023395|mint:Q9UBX3|reactome:R-HSA-1614517|reactome:R-HSA-428643|genbank_nucl_gi:20137671(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606	rogid:Z9a7UxJbOLZqoCyz+5L+mbkXFqk9606	rigid:JlcAakjTQyGVKzQW+lhRzuumwC0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWF2	uniprotkb:O14936	intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401	intact:EBI-1215506|uniprotkb:Q5VT18|uniprotkb:Q5VT19|uniprotkb:Q66T42|uniprotkb:A6NES1|uniprotkb:O43215|uniprotkb:Q17RI4|uniprotkb:Q59HA0|uniprotkb:Q5VT16|uniprotkb:Q5VT17|uniprotkb:Q9BYH6|uniprotkb:Q9NYB2|uniprotkb:Q9NYB3|uniprotkb:B7ZKY0|ensembl:ENSP00000367405	psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym)	psi-mi:cskp_human(display_long)|uniprotkb:CASK(gene name)|psi-mi:CASK(display_short)|uniprotkb:LIN2(gene name synonym)|uniprotkb:Calcium/calmodulin-dependent serine protein kinase(gene name synonym)|uniprotkb:Protein lin-2 homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770736|imex:IM-28143-58	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N	refseq:NP_001119526.1|refseq:NP_001119527.1|refseq:NP_003679.2|dip:DIP-38727N|ensembl:ENSG00000147044(gene)|ensembl:ENST00000378163(transcript)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031982"(vesicle)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060170"(ciliary membrane)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0070509"(calcium ion import)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0090288"(negative regulation of cellular response to growth factor stimulus)|rcsb pdb:3MFT|rcsb pdb:3MFU|rcsb pdb:3TAC|rcsb pdb:6KMH|rcsb pdb:7OAI|rcsb pdb:7OAJ|rcsb pdb:7OAK|rcsb pdb:7OAL|reactome:R-HSA-212676|reactome:R-HSA-3000170|reactome:R-HSA-373753|reactome:R-HSA-6794361|reactome:R-HSA-9609736|reactome:R-HSA-9662360|reactome:R-HSA-9662361|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014775(L27, C-terminal)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035473|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:O14936|rcsb pdb:1KGD|rcsb pdb:1KWA|rcsb pdb:1ZL8|rcsb pdb:3C0G|rcsb pdb:3C0H|rcsb pdb:3C0I|rcsb pdb:3MFR|rcsb pdb:3MFS|genbank_nucl_gi:186700627(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606	rogid:zTaBgQexJON3EVgJq9FHjf+aSCY9606	rigid:JlcAakjTQyGVKzQW+lhRzuumwC0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWF2	uniprotkb:Q9BPW8	intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401	intact:EBI-307125|uniprotkb:O43800|uniprotkb:B2RAY3|ensembl:ENSP00000216121	psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym)	psi-mi:nips1_human(display_long)|uniprotkb:NIPSNAP1(gene name)|psi-mi:NIPSNAP1(display_short)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770736|imex:IM-28143-58	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N	refseq:NP_001189431.1|refseq:NP_003625.2|ensembl:ENSG00000184117(gene)|ensembl:ENST00000216121(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0097060"(synaptic membrane)|interpro:IPR011008(Dimeric alpha-beta barrel)|interpro:IPR012577(NIPSNAP)|mint:Q9BPW8|genbank_nucl_gi:17380144(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606	rogid:mOosuRNhEeYvVB5cUbkMzTJ7X7s9606	rigid:JlcAakjTQyGVKzQW+lhRzuumwC0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWF2	uniprotkb:P51151	intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401	intact:EBI-4401353|uniprotkb:Q6ICN1|uniprotkb:A8K390|ensembl:ENSP00000420127|ensembl:ENSP00000480777	psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym)	psi-mi:rab9a_human(display_long)|uniprotkb:RAB9A(gene name)|psi-mi:RAB9A(display_short)|uniprotkb:RAB9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770736|imex:IM-28143-58	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N	refseq:XP_016885453.1|refseq:NP_001182257.1|refseq:NP_004242.1|dip:DIP-46409N|ensembl:ENSG00000123595(gene)|ensembl:ENST00000464506(transcript)|ensembl:ENST00000618931(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042470"(melanosome)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0052405"|go:"GO:0070062"(extracellular exosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041824|mint:P51151|rcsb pdb:1WMS|reactome:R-HSA-6811440|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9706019|genbank_nucl_gi:1710003(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606	rogid:x0BjgzGEj7mPNlt2CQLkHtqQzDQ9606	rigid:JlcAakjTQyGVKzQW+lhRzuumwC0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWF2	uniprotkb:P50402	intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401	intact:EBI-489887|uniprotkb:Q6FI02|ensembl:ENSP00000358857|ensembl:ENSP00000507533	psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym)	psi-mi:emd_human(display_long)|uniprotkb:EDMD(gene name synonym)|uniprotkb:STA(gene name synonym)|uniprotkb:EMD(gene name)|psi-mi:EMD(display_short)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770736|imex:IM-28143-58	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N	refseq:NP_000108.1|ensembl:ENSP00000358857|ensembl:ENSP00000507533|ensembl:ENSG00000102119(gene)|ensembl:ENST00000369842(transcript)|ensembl:ENST00000683627(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR011015(LEM-like fold)|interpro:IPR034989|interpro:IPR035004|mint:P50402|rcsb pdb:1JEI|rcsb pdb:2ODC|rcsb pdb:2ODG|rcsb pdb:6GHD|rcsb pdb:6RPR|rcsb pdb:7NDY|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609523|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|dip:DIP-34638N|genbank_nucl_gi:1706639(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606	rogid:hqH2sFjAGwjIGtGX/rjVVFgaYsE9606	rigid:JlcAakjTQyGVKzQW+lhRzuumwC0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWF2	uniprotkb:P78527	intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401	intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420	psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym)	psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770736|imex:IM-28143-58	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N	refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N|genbank_nucl_gi:126032350(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606	rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606	rigid:JlcAakjTQyGVKzQW+lhRzuumwC0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWF2	uniprotkb:P05783	intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401	intact:EBI-297888|uniprotkb:Q53G38|uniprotkb:Q5U0N8|uniprotkb:Q9BW26|ensembl:ENSP00000373487|ensembl:ENSP00000373489	psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym)	psi-mi:k1c18_human(display_long)|uniprotkb:KRT18(gene name)|psi-mi:KRT18(display_short)|uniprotkb:CYK18(gene name synonym)|uniprotkb:Keratin-18(gene name synonym)|uniprotkb:PIG46(orf name)|uniprotkb:Cytokeratin-18(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 46 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770736|imex:IM-28143-58	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N	go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005912"(adherens junction)|go:"GO:0007049"(cell cycle)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009750"(response to fructose)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034451"(centriolar satellite)|go:"GO:0043000"(Golgi to plasma membrane CFTR protein transport)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045095"(keratin filament)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0072497"(mesenchymal stem cell differentiation)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1902488"(cholangiocyte apoptotic process)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR027695|interpro:IPR039008|mint:P05783|reactome:R-HSA-6805567|reactome:R-HSA-6809371|ensembl:ENSG00000111057(gene)|ensembl:ENST00000388835(transcript)|ensembl:ENST00000388837(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|refseq:NP_000215.1|refseq:NP_954657.1|dip:DIP-633N|genbank_nucl_gi:125083(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606	rogid:6rtLZxuG0CSGcsCHEmkRKFVDeyo9606	rigid:JlcAakjTQyGVKzQW+lhRzuumwC0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWF2	uniprotkb:Q9P2K2	intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401	intact:EBI-11126467|uniprotkb:Q9H9W7|uniprotkb:A7E260|uniprotkb:A7MD07|uniprotkb:B9EH67|uniprotkb:A5PKW9|ensembl:ENSP00000281741	psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym)	psi-mi:txd16_human(display_long)|uniprotkb:TXNDC16(gene name)|psi-mi:TXNDC16(display_short)|uniprotkb:KIAA1344(gene name synonym)|uniprotkb:ERP90(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770736|imex:IM-28143-58	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N	refseq:NP_001153519.1|refseq:NP_065835.2|ensembl:ENSG00000087301(gene)|ensembl:ENST00000281741(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR040090|genbank_nucl_gi:117949599(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606	rogid:zzfV8NEefGI6L0ra5Z/bEg3WfEU9606	rigid:JlcAakjTQyGVKzQW+lhRzuumwC0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWF2	uniprotkb:P21333	intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401	intact:EBI-350432|uniprotkb:Q8NF52|intact:EBI-1103234|ensembl:ENSP00000358866|uniprotkb:Q5HY53|uniprotkb:Q5HY55|uniprotkb:E9KL45	psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym)	psi-mi:flna_human(display_long)|uniprotkb:FLNA(gene name)|psi-mi:FLNA(display_short)|uniprotkb:FLN(gene name synonym)|uniprotkb:FLN1(gene name synonym)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770736|imex:IM-28143-58	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N	go:"GO:0007195"(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:"GO:1902396"(protein localization to bicellular tight junction)|refseq:NP_001104026.1|refseq:NP_001447.2|ensembl:ENSG00000196924(gene)|ensembl:ENST00000369850(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097368"(establishment of Sertoli cell barrier)|go:"GO:0097440"(apical dendrite)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:0046332"(SMAD binding)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0019900"(kinase binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031523"(Myb complex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045296"(cadherin binding)|reactome:R-HSA-114608|reactome:R-HSA-430116|reactome:R-HSA-446353|reactome:R-HSA-5627123|reactome:R-HSA-8983711|rcsb pdb:6EW1|go:"GO:1905031"(regulation of membrane repolarization during cardiac muscle cell action potential)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:P21333|rcsb pdb:2AAV|rcsb pdb:2BP3|rcsb pdb:2BRQ|rcsb pdb:2J3S|rcsb pdb:2JF1|rcsb pdb:2K3T|rcsb pdb:2K7P|rcsb pdb:2K7Q|rcsb pdb:2MTP|rcsb pdb:2W0P|rcsb pdb:2WFN|rcsb pdb:3CNK|rcsb pdb:3HOC|rcsb pdb:3HOP|rcsb pdb:3HOR|rcsb pdb:3ISW|rcsb pdb:3RGH|rcsb pdb:4M9P|rcsb pdb:4P3W|rcsb pdb:5XR1|rcsb pdb:6D8C|go:"GO:1905000"(regulation of membrane repolarization during atrial cardiac muscle cell action potential)|dip:DIP-1136N|genbank_nucl_gi:116063573(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606	rogid:ZxGK5OSMy8cNsyt7Ax2KXb8bn9M9606	rigid:JlcAakjTQyGVKzQW+lhRzuumwC0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWF2	uniprotkb:P45880	intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401	intact:EBI-354022|ensembl:ENSP00000361686|ensembl:ENSP00000443092|uniprotkb:Q5VWK1|uniprotkb:Q5VWK3|uniprotkb:Q6IB40|uniprotkb:Q7L3J5|uniprotkb:Q9BWK8|uniprotkb:Q9Y5I6	psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym)	psi-mi:vdac2_human(display_long)|uniprotkb:VDAC2(gene name)|psi-mi:VDAC2(display_short)|uniprotkb:Outer mitochondrial membrane protein porin 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770736|imex:IM-28143-58	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N	ensembl:ENSG00000165637(gene)|ensembl:ENST00000332211(transcript)|ensembl:ENST00000543351(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006820"(anion transport)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031966"(mitochondrial membrane)|refseq:NP_001171712.1|refseq:NP_001171752.1|refseq:NP_003366.2|refseq:NP_001311017.1|go:"GO:0032272"(negative regulation of protein polymerization)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046930"(pore complex)|go:"GO:0097001"(ceramide binding)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030277|mint:P45880|reactome:R-HSA-5689880|reactome:R-HSA-8949215|genbank_nucl_gi:113412878(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606	rogid:seQxCd19Z2HmpXcwb48osAuuafA9606	rigid:JlcAakjTQyGVKzQW+lhRzuumwC0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:P55072	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771162|imex:IM-28143-44	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N|genbank_nucl_gi:6094447(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606	rigid:0AngWHwbANANR/qiWWwHAJnADb0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:P60900	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-357793|uniprotkb:P34062|uniprotkb:Q6IB60|uniprotkb:B2R7J9|uniprotkb:B4DQR4|uniprotkb:B4DXJ9|ensembl:ENSP00000261479	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:psa6_human(display_long)|uniprotkb:PSMA6(gene name)|psi-mi:PSMA6(display_short)|uniprotkb:PROS27(gene name synonym)|uniprotkb:Proteasome iota chain(gene name synonym)|uniprotkb:Macropain iota chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex iota chain(gene name synonym)|uniprotkb:27 kDa prosomal protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771162|imex:IM-28143-44	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_002782.1|refseq:NP_001269162.1|refseq:NP_001269163.1|refseq:XP_016876957.1|refseq:NP_001269161.1|ensembl:ENSG00000100902(gene)|ensembl:ENST00000261479(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0035639"(purine ribonucleoside triphosphate binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034642|mint:P60900|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-29367N|genbank_nucl_gi:46397659(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:F+Kwr6rnDS3jD53gBGHDIn7HV/89606	rigid:0AngWHwbANANR/qiWWwHAJnADb0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:Q14997	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-1236916|uniprotkb:Q1XBG4|uniprotkb:Q1XBG5|uniprotkb:Q1XBG6|uniprotkb:Q2M1Z0|uniprotkb:Q6IPR2|uniprotkb:Q86XF8|ensembl:ENSP00000384211	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:psme4_human(display_long)|uniprotkb:PSME4(gene name)|psi-mi:PSME4(display_short)|uniprotkb:KIAA0077(gene name synonym)|uniprotkb:Proteasome activator PA200(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771162|imex:IM-28143-44	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_055429.2|dip:DIP-38203N|ensembl:ENSG00000068878(gene)|ensembl:ENST00000404125(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0035093"(spermatogenesis, exchange of chromosomal proteins)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070628"(proteasome binding)|go:"GO:1990111"(spermatoproteasome complex)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021843|interpro:IPR032430|interpro:IPR035309|mint:Q14997|rcsb pdb:6KWX|rcsb pdb:6KWY|rcsb pdb:6REY|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-983168|reactome:R-HSA-8932339|genbank_nucl_gi:40788003(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:wKVv+GwMVpoOZZS1eNP+rDe85tE9606	rigid:0AngWHwbANANR/qiWWwHAJnADb0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:P28066	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-355475|uniprotkb:B4E2V4|uniprotkb:Q6IBF7|uniprotkb:Q3T1C1|uniprotkb:B2R8F6|ensembl:ENSP00000271308	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:psa5_human(display_long)|uniprotkb:PSMA5(gene name)|psi-mi:PSMA5(display_short)|uniprotkb:Proteasome zeta chain(gene name synonym)|uniprotkb:Macropain zeta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex zeta chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771162|imex:IM-28143-44	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_001186701.1|refseq:NP_001186702.1|refseq:NP_001186703.1|refseq:NP_002781.2|ensembl:ENSG00000143106(gene)|ensembl:ENST00000271308(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR033812|mint:P28066|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEY|rcsb pdb:5LEX|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-29368N|genbank_nucl_gi:38258905(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:bfMG3npzVetUH1tahr2MAI4R+3g9606	rigid:0AngWHwbANANR/qiWWwHAJnADb0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:O94905	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-4400770|uniprotkb:A0JLQ1|uniprotkb:A8K5S9|uniprotkb:B4DM38|uniprotkb:D3DSW0|uniprotkb:Q6NW21|uniprotkb:Q86VS6|uniprotkb:Q86W49|ensembl:ENSP00000428112	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:erln2_human(display_long)|uniprotkb:ERLIN2(gene name)|psi-mi:ERLIN2(display_short)|uniprotkb:C8orf2(gene name synonym)|uniprotkb:SPFH2(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 2(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2(gene name synonym)|uniprotkb:UNQ2441/PRO5003/PRO9924(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771162|imex:IM-28143-44	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_001003790.1|refseq:NP_001003791.1|refseq:NP_009106.1|refseq:XP_016868489.1|refseq:XP_005273449.1|ensembl:ENSG00000147475(gene)|ensembl:ENST00000519638(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045121"(membrane raft)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O94905|reactome:R-HSA-382556|reactome:R-HSA-5655302|reactome:R-HSA-5678895|reactome:R-HSA-8853336|genbank_nucl_gi:38257366(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:Evjg3G0FFeQ499BNlJxpK6t8to89606	rigid:0AngWHwbANANR/qiWWwHAJnADb0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:P60604	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-1051028|uniprotkb:P56554|uniprotkb:A8K3L4|uniprotkb:D3DSL7|uniprotkb:A6NMQ7|ensembl:ENSP00000338348	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:ub2g2_human(display_long)|uniprotkb:Ubiquitin-protein ligase G2(gene name synonym)|uniprotkb:Ubiquitin carrier protein G2(gene name synonym)|uniprotkb:UBE2G2(gene name)|psi-mi:UBE2G2(display_short)|uniprotkb:E2 ubiquitin-conjugating enzyme G2(gene name synonym)|uniprotkb:UBC7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771162|imex:IM-28143-44	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_001189418.1|refseq:NP_003334.2|refseq:NP_872630.1|refseq:XP_016883958.1|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2CYX|rcsb pdb:2KLY|rcsb pdb:2LXP|rcsb pdb:3H8K|rcsb pdb:4LAD|reactome:R-HSA-8866652|reactome:R-HSA-983168|ensembl:ENSG00000184787(gene)|ensembl:ENST00000345496(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-50750N|genbank_nucl_gi:33359701(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:Q/uslqX/WH/SxKEPYeMmU9CjTBI9606	rigid:0AngWHwbANANR/qiWWwHAJnADb0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:P49720	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-603340|uniprotkb:P31147|uniprotkb:Q0P6J7|uniprotkb:Q96E27|ensembl:ENSP00000483688|ensembl:ENSP00000483956	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:psb3_human(display_long)|uniprotkb:PSMB3(gene name)|psi-mi:PSMB3(display_short)|uniprotkb:Proteasome theta chain(gene name synonym)|uniprotkb:Proteasome chain 13(gene name synonym)|uniprotkb:Proteasome component C10-II(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771162|imex:IM-28143-44	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_002786.2|dip:DIP-33846N|ensembl:ENSG00000275903(gene)|ensembl:ENSG00000277791(gene)|ensembl:ENST00000619426(transcript)|ensembl:ENST00000619951(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR033811|mint:P49720|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|genbank_nucl_gi:20532411(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:H4UDdXV1BaXHp6mEPafNy+Iv8389606	rigid:0AngWHwbANANR/qiWWwHAJnADb0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:P28072	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-359288|uniprotkb:Q96J55|ensembl:ENSP00000270586	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:psb6_human(display_long)|uniprotkb:PSMB6(gene name)|psi-mi:PSMB6(display_short)|uniprotkb:LMPY(gene name synonym)|uniprotkb:Proteasome delta chain(gene name synonym)|uniprotkb:Macropain delta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex delta chain(gene name synonym)|uniprotkb:Proteasome subunit Y(gene name synonym)|uniprotkb:Y(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771162|imex:IM-28143-44	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_002789.1|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035140|mint:P28072|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|go:"GO:0005737"(cytoplasm)|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000142507(gene)|ensembl:ENST00000270586(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-33847N|genbank_nucl_gi:20532407(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:4LRxYA6/tM2hsc96iP29c5J7ew49606	rigid:0AngWHwbANANR/qiWWwHAJnADb0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:P49721	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-359335|uniprotkb:P31145|uniprotkb:Q9BWZ9|uniprotkb:D3DPS0|ensembl:ENSP00000362334	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:psb2_human(display_long)|uniprotkb:PSMB2(gene name)|psi-mi:PSMB2(display_short)|uniprotkb:Multicatalytic endopeptidase complex subunit C7-I(gene name synonym)|uniprotkb:Proteasome component C7-I(gene name synonym)|uniprotkb:Macropain subunit C7-I(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771162|imex:IM-28143-44	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_002785.1|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5GJR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-5689603|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000126067(gene)|ensembl:ENST00000373237(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|mint:P49721|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|dip:DIP-33848N|genbank_nucl_gi:1709762(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:PvXrk6RLayQ1zqmavn1cONfA9/A9606	rigid:0AngWHwbANANR/qiWWwHAJnADb0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:P25789	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-359310|uniprotkb:Q8TBD1|uniprotkb:Q53XP2|ensembl:ENSP00000044462|ensembl:ENSP00000453887|uniprotkb:D3DW86|uniprotkb:Q567Q5	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:psa4_human(display_long)|uniprotkb:PSMA4(gene name)|psi-mi:PSMA4(display_short)|uniprotkb:PSC9(gene name synonym)|uniprotkb:Proteasome component C9(gene name synonym)|uniprotkb:Macropain subunit C9(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C9(gene name synonym)|uniprotkb:Proteasome subunit L(gene name synonym)|uniprotkb:HC9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771162|imex:IM-28143-44	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_001096137.1|refseq:NP_002780.1|rcsb pdb:6XMJ|reactome:R-HSA-2467813|reactome:R-HSA-2871837|rcsb pdb:7AWE|reactome:R-HSA-349425|reactome:R-HSA-1169091|reactome:R-HSA-350562|reactome:R-HSA-1234176|reactome:R-HSA-382556|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-450408|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-4641258|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5358346|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000041357(gene)|ensembl:ENST00000044462(transcript)|ensembl:ENST00000559082(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034647|mint:P25789|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|refseq:NP_001096138.1|refseq:NP_001317605.1|dip:DIP-29365N|genbank_nucl_gi:130861(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:u+wKxvIa9JKb4Zu9K+tnY3d26tw9606	rigid:0AngWHwbANANR/qiWWwHAJnADb0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:P25788	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-348380|ensembl:ENSP00000216455|uniprotkb:Q86U83|uniprotkb:Q8N1D8|uniprotkb:Q9BS70|uniprotkb:B2RCK6	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:psa3_human(display_long)|uniprotkb:PSMA3(gene name)|psi-mi:PSMA3(display_short)|uniprotkb:PSC8(gene name synonym)|uniprotkb:Proteasome component C8(gene name synonym)|uniprotkb:Macropain subunit C8(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C8(gene name synonym)|uniprotkb:HC8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771162|imex:IM-28143-44	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_002779.1|refseq:NP_687033.1|ensembl:ENSG00000100567(gene)|ensembl:ENST00000216455(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0045202"(synapse)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR037555|mint:P25788|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|rcsb pdb:5DSV|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|rcsb pdb:7E55|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|rcsb pdb:5T0H|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-174084|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-174113|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|dip:DIP-29366N|genbank_nucl_gi:130859(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:9Er/PY50/GVoCr5yAPXlkfxtP0k9606	rigid:0AngWHwbANANR/qiWWwHAJnADb0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:P20618	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-372273|uniprotkb:Q9BWA8|ensembl:ENSP00000262193|uniprotkb:B5BU76	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:psb1_human(display_long)|uniprotkb:PSMB1(gene name)|psi-mi:PSMB1(display_short)|uniprotkb:PSC5(gene name synonym)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Macropain subunit C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym)|uniprotkb:Proteasome gamma chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771162|imex:IM-28143-44	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	ensembl:ENSG00000008018(gene)|ensembl:ENST00000262193(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|mint:P20618|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|refseq:NP_002784.1|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M2B|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5LF1|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4608870|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-983168|reactome:R-HSA-9604323|dip:DIP-31193N|genbank_nucl_gi:130853(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:DfIS480BUnqbXus9/KoojdkWgw09606	rigid:0AngWHwbANANR/qiWWwHAJnADb0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:P25787	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-603262|uniprotkb:Q9BU45|ensembl:ENSP00000223321|intact:EBI-1237095|uniprotkb:Q6ICS6	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:psa2_human(display_long)|uniprotkb:PSMA2(gene name)|psi-mi:PSMA2(display_short)|uniprotkb:PSC3(gene name synonym)|uniprotkb:Proteasome component C3(gene name synonym)|uniprotkb:Macropain subunit C3(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C3(gene name synonym)|uniprotkb:HC3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771162|imex:IM-28143-44	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	mint:P25787|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|ensembl:ENSG00000106588(gene)|ensembl:ENST00000223321(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0009615"(response to virus)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|refseq:NP_002778.1|dip:DIP-29364N|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|genbank_nucl_gi:130850(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:COncAMXXqT+zAHA/nK+7dweRg9A9606	rigid:0AngWHwbANANR/qiWWwHAJnADb0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:P25786	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-359352|uniprotkb:Q9BRV9|uniprotkb:A8K400|uniprotkb:Q53YE8|ensembl:ENSP00000379676	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:psa1_human(display_long)|uniprotkb:PSMA1(gene name)|psi-mi:PSMA1(display_short)|uniprotkb:PROS30(gene name synonym)|uniprotkb:PSC2(gene name synonym)|uniprotkb:Proteasome component C2(gene name synonym)|uniprotkb:Macropain subunit C2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C2(gene name synonym)|uniprotkb:Proteasome nu chain(gene name synonym)|uniprotkb:30 kDa prosomal protein(gene name synonym)|uniprotkb:HC2(gene name synonym)|uniprotkb:NU(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771162|imex:IM-28143-44	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_002777.1|refseq:NP_683877.1|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000129084(gene)|ensembl:ENST00000396394(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|mint:P25786|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|dip:DIP-29369N|genbank_nucl_gi:130848(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:tAADzZ1G9E/0BBeS8vybNx97v7k9606	rigid:0AngWHwbANANR/qiWWwHAJnADb0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:O14818	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-603272|uniprotkb:Q9BR53|uniprotkb:Q9H4K5|uniprotkb:Q9UEU8|uniprotkb:B2R515|uniprotkb:Q5JXJ2|ensembl:ENSP00000359910	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:psa7_human(display_long)|uniprotkb:PSMA7(gene name)|psi-mi:PSMA7(display_short)|uniprotkb:Proteasome subunit RC6-1(gene name synonym)|uniprotkb:Proteasome subunit XAPC7(gene name synonym)|uniprotkb:HSPC(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771162|imex:IM-28143-44	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_002783.1|dip:DIP-29363N|ensembl:ENSG00000101182(gene)|ensembl:ENST00000370873(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098794"(postsynapse)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035190|mint:O14818|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|genbank_nucl_gi:12643540(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:J1M+b+VK02BAn2OnZISjjlmO8dc9606	rigid:0AngWHwbANANR/qiWWwHAJnADb0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:P28070	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-603350|uniprotkb:P31148|uniprotkb:Q5SZS5|uniprotkb:Q969L6|uniprotkb:B2R9L3|uniprotkb:Q6IBI4|ensembl:ENSP00000290541	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:psb4_human(display_long)|uniprotkb:PSMB4(gene name)|psi-mi:PSMB4(display_short)|uniprotkb:Macropain beta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex beta chain(gene name synonym)|uniprotkb:Proteasome chain 3(gene name synonym)|uniprotkb:26 kDa prosomal protein(gene name synonym)|uniprotkb:PROS26(gene name synonym)|uniprotkb:Proteasome beta chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771162|imex:IM-28143-44	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_002787.2|dip:DIP-33844N|ensembl:ENSG00000159377(gene)|ensembl:ENST00000290541(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR016295(Proteasome endopeptidase complex, beta subunit)|interpro:IPR023333|interpro:IPR029055|mint:P28070|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|genbank_nucl_gi:116242733(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:drR+ktPXQK9ep6hs7OYb5SmQnXU9606	rigid:0AngWHwbANANR/qiWWwHAJnADb0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96DZ1	uniprotkb:Q9H3G5	intact:EBI-1023677|uniprotkb:O95901|uniprotkb:Q6UWN7|uniprotkb:Q9NUY7|uniprotkb:Q9UQL4|uniprotkb:B2RDB4|ensembl:ENSP00000185150|uniprotkb:B5MC72	intact:EBI-357542|uniprotkb:Q6UX20|uniprotkb:Q8NBL7|uniprotkb:Q96AR7|uniprotkb:Q9HB41|ensembl:ENSP00000265394|ensembl:ENSP00000379572|ensembl:ENSP00000387164|intact:EBI-1058665|uniprotkb:A4D1A4	psi-mi:erlec_human(display_long)|uniprotkb:ER lectin(gene name synonym)|uniprotkb:ERLEC1(gene name)|psi-mi:ERLEC1(display_short)|uniprotkb:XTP3TPB(gene name synonym)|uniprotkb:UNQ1878/PRO4321(orf name)|uniprotkb:C2orf30(gene name synonym)|uniprotkb:XTP3-transactivated gene B protein(gene name synonym)	psi-mi:cpvl_human(display_long)|uniprotkb:CPVL(gene name)|psi-mi:CPVL(display_short)|uniprotkb:VLP(gene name synonym)|uniprotkb:UNQ197/PRO223(orf name)|uniprotkb:PSEC0124(orf name)|uniprotkb:Carboxypeptidase, vitellogenic-like(gene name synonym)|uniprotkb:Vitellogenic carboxypeptidase-like protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771246|imex:IM-28143-84	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120870.1|refseq:NP_056516.2|ensembl:ENSG00000068912(gene)|ensembl:ENST00000185150(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR044865|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|refseq:NP_001120869.1	ensembl:ENSG00000106066(gene)|ensembl:ENST00000265394(transcript)|ensembl:ENST00000396276(transcript)|ensembl:ENST00000409850(transcript)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR029058|mint:Q9H3G5|refseq:NP_061902.2|refseq:NP_112601.3|refseq:XP_011513739.1|refseq:NP_001334981.1|refseq:NP_001334983.1|genbank_nucl_gi:67476930(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:eBOyI1TfCgExBrXLxSwlUZ05NXs9606	rogid:antgab61u6D+KmbopQeowXqSqWQ9606	rigid:oOOM6fn+kqCaLdVlIijmasPdhVw	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96DZ1	uniprotkb:Q9UBV2	intact:EBI-1023677|uniprotkb:O95901|uniprotkb:Q6UWN7|uniprotkb:Q9NUY7|uniprotkb:Q9UQL4|uniprotkb:B2RDB4|ensembl:ENSP00000185150|uniprotkb:B5MC72	intact:EBI-358766|uniprotkb:Q6UWT6|uniprotkb:Q9P1T9|uniprotkb:Q9UHK7|ensembl:ENSP00000337053	psi-mi:erlec_human(display_long)|uniprotkb:ER lectin(gene name synonym)|uniprotkb:ERLEC1(gene name)|psi-mi:ERLEC1(display_short)|uniprotkb:XTP3TPB(gene name synonym)|uniprotkb:UNQ1878/PRO4321(orf name)|uniprotkb:C2orf30(gene name synonym)|uniprotkb:XTP3-transactivated gene B protein(gene name synonym)	psi-mi:se1l1_human(display_long)|uniprotkb:SEL1L(gene name)|psi-mi:SEL1L(display_short)|uniprotkb:TSA305(gene name synonym)|uniprotkb:UNQ128/PRO1063(orf name)|uniprotkb:Suppressor of lin-12-like protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771246|imex:IM-28143-84	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120870.1|refseq:NP_056516.2|ensembl:ENSG00000068912(gene)|ensembl:ENST00000185150(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR044865|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|refseq:NP_001120869.1	refseq:NP_001231913.1|refseq:NP_005056.3|ensembl:ENSG00000071537(gene)|ensembl:ENST00000336735(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0050821"(protein stabilization)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|mint:Q9UBV2|reactome:R-HSA-1912420|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-46259N|genbank_nucl_gi:62512184(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:eBOyI1TfCgExBrXLxSwlUZ05NXs9606	rogid:eufE+8nfcHK8CDl+AQ5G+3NtL+09606	rigid:oOOM6fn+kqCaLdVlIijmasPdhVw	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14139	uniprotkb:Q92575	intact:EBI-1048119|uniprotkb:Q2M1H0|uniprotkb:Q6P5T4|uniprotkb:Q7Z639|uniprotkb:B0YJB6|ensembl:ENSP00000252108	intact:EBI-723441|uniprotkb:Q4ZG56|uniprotkb:Q8IYM5|intact:EBI-28978946|ensembl:ENSP00000272638|uniprotkb:A8K9W4	psi-mi:ube4a_human(display_long)|uniprotkb:UBE4A(gene name)|psi-mi:UBE4A(display_short)|uniprotkb:KIAA0126(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase E4 A(gene name synonym)	psi-mi:ubxn4_human(display_long)|uniprotkb:Erasin(gene name synonym)|uniprotkb:UBXN4(gene name)|psi-mi:UBXN4(display_short)|uniprotkb:KIAA0242(gene name synonym)|uniprotkb:UBXDC1(gene name synonym)|uniprotkb:UBXD2(gene name synonym)|uniprotkb:UBX domain-containing protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771321|imex:IM-28143-46	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191006.1|refseq:NP_004779.2|ensembl:ENSG00000110344(gene)|ensembl:ENST00000252108(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019474|rcsb pdb:1WGM|reactome:R-HSA-983168|genbank_nucl_gi:71164791(identity)	refseq:NP_055422.1|ensembl:ENSG00000144224(gene)|ensembl:ENST00000272638(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|interpro:IPR001012(UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:2KXJ|ensembl:ENSP00000272638	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/05	rogid:nk+uYWQ8ytS/qOjUkCDf9dAymPU9606	rogid:rWCmtHlje9EFw7YVQQNJBBH4bLE9606	rigid:ilKVqM9Mh4zSJRTVLN6XEinxPiQ	false	-	s tag:?-?	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:Q96CS3	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771333|imex:IM-28143-64	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N|genbank_nucl_gi:74731375(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rigid:xnCy73U2UmKHquqau8fHzhU6WV4	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:Q86VP6	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-456077|uniprotkb:O94918|uniprotkb:Q6PIY4|uniprotkb:Q8NDJ4|uniprotkb:Q96JZ9|uniprotkb:Q96T19|uniprotkb:Q9BTC4|uniprotkb:Q9H0G2|uniprotkb:Q9P0H7|uniprotkb:Q9UF85|uniprotkb:B2RAU3|ensembl:ENSP00000442318	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:cand1_human(display_long)|uniprotkb:KIAA0829(gene name synonym)|uniprotkb:TIP120(gene name synonym)|uniprotkb:TIP120A(gene name synonym)|uniprotkb:Cullin-associated and neddylation-dissociated protein 1(gene name synonym)|uniprotkb:p120 CAND1(gene name synonym)|uniprotkb:TBP-interacting protein of 120 kDa A(gene name synonym)|uniprotkb:CAND1(gene name)|psi-mi:CAND1(display_short)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771333|imex:IM-28143-64	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	refseq:NP_060918.2|dip:DIP-31608N|ensembl:ENSG00000111530(gene)|ensembl:ENST00000545606(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010265"(SCF complex assembly)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR013932("TATA-binding protein interacting (TIP20)")|interpro:IPR039852|mint:Q86VP6|rcsb pdb:1U6G|rcsb pdb:4A0C|reactome:R-HSA-6798695|reactome:R-HSA-8951664|reactome:R-HSA-917937|interpro:IPR016024(Armadillo-type fold)|genbank_nucl_gi:67460541(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:2lBY8xJXlGZL+xyo/dyB2WzuNqs9606	rigid:xnCy73U2UmKHquqau8fHzhU6WV4	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:P68133	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-367510|uniprotkb:P02568|uniprotkb:P99020|ensembl:ENSP00000355645|uniprotkb:Q5T8M9	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:acts_human(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771333|imex:IM-28143-64	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	ensembl:ENSG00000143632(gene)|ensembl:ENST00000366684(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017022"(myosin binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0043531"(ADP binding)|go:"GO:0044297"(cell body)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072562"(blood microparticle)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68133|reactome:R-HSA-390522|go:"GO:0001725"(stress fiber)|refseq:NP_001091.1|genbank_nucl_gi:61218043(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:2vZu8ElmMe+6GjKBliCAatNGZR49606	rigid:xnCy73U2UmKHquqau8fHzhU6WV4	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:Q9HA65	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-714625|ensembl:ENSP00000221543|ensembl:ENSP00000446323|uniprotkb:B9A6L8|uniprotkb:B4DT12|uniprotkb:F5H1W7	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:tbc17_human(display_long)|uniprotkb:TBC1D17(gene name)|psi-mi:TBC1D17(display_short)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771333|imex:IM-28143-64	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	refseq:NP_001161694.1|ensembl:ENSG00000104946(gene)|ensembl:ENST00000221543(transcript)|ensembl:ENST00000535102(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR021935|interpro:IPR035969|reactome:R-HSA-8854214|go:"GO:0090630"(activation of GTPase activity)|refseq:NP_078958.2|go:"GO:0055037"(recycling endosome)|genbank_nucl_gi:59798974(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:/FUNCWD2xK94tfYIyhG5trPsFMs9606	rigid:xnCy73U2UmKHquqau8fHzhU6WV4	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:Q92616	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-356221|ensembl:ENSP00000300648|uniprotkb:O95001|uniprotkb:O95651|uniprotkb:Q6P2S3|uniprotkb:Q86X65|uniprotkb:Q8N5I5|uniprotkb:Q8WU80|uniprotkb:Q99736|uniprotkb:Q9UE60|uniprotkb:A8KAY1|intact:EBI-1058692	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:gcn1_human(display_long)|uniprotkb:GCN1(gene name)|psi-mi:GCN1(display_short)|uniprotkb:GCN1 eIF-2-alpha kinase activator homolog(gene name synonym)|uniprotkb:GCN1-like protein 1(gene name synonym)|uniprotkb:GCN1L1(gene name synonym)|uniprotkb:General control of amino-acid synthesis 1-like protein 1(gene name synonym)|uniprotkb:KIAA0219(gene name synonym)|uniprotkb:Translational activator GCN1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771333|imex:IM-28143-64	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	ensembl:ENSG00000089154(gene)|ensembl:ENST00000300648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0043022"(ribosome binding)|go:"GO:0045296"(cadherin binding)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR033173|interpro:IPR034085|mint:Q92616|reactome:R-HSA-9633012|go:"GO:0005844"(polysome)|refseq:NP_006827.1|genbank_nucl_gi:54607053(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:NtSEW6xjvCkUyb40cnk0JdL5PcA9606	rigid:xnCy73U2UmKHquqau8fHzhU6WV4	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:O94905	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-4400770|uniprotkb:A0JLQ1|uniprotkb:A8K5S9|uniprotkb:B4DM38|uniprotkb:D3DSW0|uniprotkb:Q6NW21|uniprotkb:Q86VS6|uniprotkb:Q86W49|ensembl:ENSP00000428112	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:erln2_human(display_long)|uniprotkb:ERLIN2(gene name)|psi-mi:ERLIN2(display_short)|uniprotkb:C8orf2(gene name synonym)|uniprotkb:SPFH2(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 2(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2(gene name synonym)|uniprotkb:UNQ2441/PRO5003/PRO9924(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771333|imex:IM-28143-64	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	refseq:NP_001003790.1|refseq:NP_001003791.1|refseq:NP_009106.1|refseq:XP_016868489.1|refseq:XP_005273449.1|ensembl:ENSG00000147475(gene)|ensembl:ENST00000519638(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045121"(membrane raft)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O94905|reactome:R-HSA-382556|reactome:R-HSA-5655302|reactome:R-HSA-5678895|reactome:R-HSA-8853336|genbank_nucl_gi:38257366(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:Evjg3G0FFeQ499BNlJxpK6t8to89606	rigid:xnCy73U2UmKHquqau8fHzhU6WV4	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:Q15286	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-722275|uniprotkb:B4E390|uniprotkb:B2R6E0|ensembl:ENSP00000229340	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:rab35_human(display_long)|uniprotkb:Ras-related protein Rab-1C(gene name synonym)|uniprotkb:GTP-binding protein RAY(gene name synonym)|uniprotkb:RAB35(gene name)|psi-mi:RAB35(display_short)|uniprotkb:RAB1C(gene name synonym)|uniprotkb:RAY(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771333|imex:IM-28143-64	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	refseq:NP_001161078.1|refseq:NP_006852.1|ensembl:ENSG00000111737(gene)|ensembl:ENST00000229340(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0008104"(protein localization)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0031253"(cell projection membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042470"(melanosome)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041815|mint:Q15286|rcsb pdb:3TW8|rcsb pdb:6EKK|rcsb pdb:6IF2|rcsb pdb:6IF3|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198|genbank_nucl_gi:3024525(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:95pH+DyDjv9FcxFeMmGYoJ0KyPo9606	rigid:xnCy73U2UmKHquqau8fHzhU6WV4	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:Q58FF8	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-2961708	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:h90b2_human(display_long)|uniprotkb:HSP90AB2P(gene name)|psi-mi:HSP90AB2P(display_short)|uniprotkb:HSP90BB(gene name synonym)|uniprotkb:Heat shock protein 90-beta b(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771333|imex:IM-28143-64	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|interpro:IPR036890|interpro:IPR037196|genbank_nucl_gi:190359598(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:SntF/u+V170yoKZScA9O/5BL3Ps9606	rigid:xnCy73U2UmKHquqau8fHzhU6WV4	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:P62269	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-352451|ensembl:ENSP00000211372|ensembl:ENSP00000393241|ensembl:ENSP00000403175|ensembl:ENSP00000412583|ensembl:ENSP00000416110|uniprotkb:P25232|uniprotkb:Q6IPF8|uniprotkb:Q5SUJ3	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:rs18_human(display_long)|uniprotkb:RPS18(gene name)|psi-mi:RPS18(display_short)|uniprotkb:D6S218E(gene name synonym)|uniprotkb:Ke-3(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS13(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771333|imex:IM-28143-64	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	refseq:NP_072045.1|ensembl:ENSG00000096150(gene)|ensembl:ENSG00000223367(gene)|ensembl:ENSG00000226225(gene)|ensembl:ENSG00000231500(gene)|ensembl:ENSG00000235650(gene)|ensembl:ENST00000211372(transcript)|ensembl:ENST00000434122(transcript)|ensembl:ENST00000439602(transcript)|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENST00000454021(transcript)|ensembl:ENST00000457341(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001892(Ribosomal protein S13)|interpro:IPR010979(Ribosomal protein S13-like, H2TH)|interpro:IPR018269|interpro:IPR027437|mint:P62269|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|dip:DIP-32892N|genbank_nucl_gi:169165559(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:yOHgKM/BuvgGdqp1OEVPeuiABg89606	rigid:xnCy73U2UmKHquqau8fHzhU6WV4	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:P46776	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-350581|uniprotkb:B2R4B3|ensembl:ENSP00000346015	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:rl27a_human(display_long)|uniprotkb:RPL27A(gene name)|psi-mi:RPL27A(display_short)|uniprotkb:Large ribosomal subunit protein uL15(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771333|imex:IM-28143-64	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	refseq:NP_000981.1|ensembl:ENSG00000166441(gene)|ensembl:ENST00000314138(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR001196(Ribosomal protein L15)|interpro:IPR021131|interpro:IPR027386|interpro:IPR030878|interpro:IPR036227|mint:P46776|rcsb pdb:4BXF|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72706|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6IP6|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6OM7|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|rcsb pdb:6IP5|dip:DIP-33121N|genbank_nucl_gi:147904567(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:tUezMQBw+SWmLYq8M0pkLCF8vO89606	rigid:xnCy73U2UmKHquqau8fHzhU6WV4	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:Q8TC07	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-1048247|uniprotkb:B9A6L6|intact:EBI-6190229|uniprotkb:B4DMT9|uniprotkb:J3KNI9|uniprotkb:Q9HA83|intact:EBI-28984447|ensembl:ENSP00000448182	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:tbc15_human(display_long)|uniprotkb:TBC1D15(gene name)|psi-mi:TBC1D15(display_short)|uniprotkb:GTPase-activating protein RAB7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771333|imex:IM-28143-64	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	refseq:NP_001139685.2|refseq:NP_001139686.1|refseq:NP_073608.4|ensembl:ENST00000319106|ensembl:ENSP00000318262|ensembl:ENST00000485960|ensembl:ENSP00000420678|ensembl:ENSP00000448182|ensembl:ENSG00000121749(gene)|ensembl:ENST00000550746(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR021935|interpro:IPR035969|reactome:R-HSA-8854214|genbank_nucl_gi:143811467(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:3tlqjLtZ/Bq5H6M00sHIwqNqqw49606	rigid:xnCy73U2UmKHquqau8fHzhU6WV4	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:O15260	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-1044848|uniprotkb:O60923|uniprotkb:Q9UNZ0|uniprotkb:Q9UNZ1|uniprotkb:Q5T8U6|ensembl:ENSP00000361057|ensembl:ENSP00000486049|uniprotkb:B7Z6A4	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:surf4_human(display_long)|uniprotkb:SURF4(gene name)|psi-mi:SURF4(display_short)|uniprotkb:SURF-4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771333|imex:IM-28143-64	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	refseq:NP_149351.1|ensembl:ENSG00000148248(gene)|ensembl:ENSG00000280951(gene)|ensembl:ENST00000629578(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035577"(azurophil granule membrane)|interpro:IPR002995(Surfeit locus 4)|mint:O15260|reactome:R-HSA-6798695|reactome:R-HSA-6811434|ensembl:ENST00000371989(transcript)|refseq:NP_001267718.1|refseq:NP_001267721.1|genbank_nucl_gi:12644052(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:VEkKSEfWLmSZx209HLRfoMMTzsg9606	rigid:xnCy73U2UmKHquqau8fHzhU6WV4	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:P78527	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771333|imex:IM-28143-64	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N|genbank_nucl_gi:126032350(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606	rigid:xnCy73U2UmKHquqau8fHzhU6WV4	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:Q9NY65	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-356246|ensembl:ENSP00000333326|uniprotkb:B3KPW9|uniprotkb:Q2M3N4|uniprotkb:B2RCX2|uniprotkb:B4DWG3	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:tba8_human(display_long)|uniprotkb:TUBA8(gene name)|psi-mi:TUBA8(display_short)|uniprotkb:TUBAL2(gene name synonym)|uniprotkb:Alpha-tubulin 8(gene name synonym)|uniprotkb:Tubulin alpha chain-like 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771333|imex:IM-28143-64	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_001180343.1|refseq:NP_061816.1|ensembl:ENSG00000183785(gene)|ensembl:ENST00000330423(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5617833|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|dip:DIP-40751N|genbank_nucl_gi:12585376(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:OGRoBAwLchNlK3LtAWkbSbCcxPQ9606	rigid:xnCy73U2UmKHquqau8fHzhU6WV4	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:O96008	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-1057581|uniprotkb:Q86VW4|uniprotkb:Q8WY09|uniprotkb:Q8WY10|uniprotkb:Q8WY11|uniprotkb:Q9BR95|uniprotkb:A0A024R0P9|ensembl:ENSP00000252487|ensembl:ENSP00000385184|ensembl:ENSP00000410339	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:tom40_human(display_long)|uniprotkb:TOMM40(gene name)|psi-mi:TOMM40(display_short)|uniprotkb:PEREC1(gene name synonym)|uniprotkb:TOM40(gene name synonym)|uniprotkb:C19orf1(gene name synonym)|uniprotkb:Translocase of outer membrane 40 kDa subunit homolog(gene name synonym)|uniprotkb:Protein Haymaker(gene name synonym)|uniprotkb:p38.5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771333|imex:IM-28143-64	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	refseq:NP_001122388.1|refseq:NP_001122389.1|refseq:NP_006105.1|ensembl:ENSG00000130204(gene)|ensembl:ENST00000252487(transcript)|ensembl:ENST00000405636(transcript)|ensembl:ENST00000426677(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006811"(ion transport)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015288"(porin activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0046930"(pore complex)|interpro:IPR023614|interpro:IPR027246|interpro:IPR037930|rcsb pdb:7CK6|rcsb pdb:7CP9|reactome:R-HSA-1268020|reactome:R-HSA-5205685|go:"GO:0005741"(mitochondrial outer membrane)|genbank_nucl_gi:12230369(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:BBV//Cb2ekmDNGHNrZuAXRgS++Y9606	rigid:xnCy73U2UmKHquqau8fHzhU6WV4	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q13438	uniprotkb:Q86WA8	intact:EBI-725454|intact:EBI-1174342|uniprotkb:A6NDD1|uniprotkb:A6NFR7|uniprotkb:A6NLB2|uniprotkb:A8K5Q9|uniprotkb:B4DPX1|uniprotkb:B4E1I6|uniprotkb:E7ENT8|uniprotkb:F8VUH2|uniprotkb:O00579|uniprotkb:Q6IBL2|uniprotkb:Q8IZ58|uniprotkb:Q9BW99|uniprotkb:B4DE28|ensembl:ENSP00000318165|uniprotkb:E7EW91|uniprotkb:G3XA88	intact:EBI-2513996|ensembl:ENSP00000285737|uniprotkb:Q96K43|uniprotkb:Q8N3B9|uniprotkb:Q0D2H6|uniprotkb:Q8NCE9|uniprotkb:B7ZKL7	psi-mi:os9_human(display_long)|uniprotkb:OS9(gene name)|psi-mi:OS9(display_short)|uniprotkb:Amplified in osteosarcoma 9(gene name synonym)	psi-mi:lonp2_human(display_long)|uniprotkb:LONP2(gene name)|psi-mi:LONP2(display_short)|uniprotkb:LONP(gene name synonym)|uniprotkb:Lon protease-like protein 2(gene name synonym)|uniprotkb:Peroxisomal Lon protease(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771036|imex:IM-28143-102	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006803.1|refseq:NP_001017956.1|refseq:NP_001017957.1|refseq:NP_001017958.1|refseq:NP_001248349.1|refseq:NP_001248350.1|refseq:NP_001248351.1|refseq:NP_001248352.1|ensembl:ENSG00000135506(gene)|ensembl:ENST00000315970(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0002020"(protease binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006605"(protein targeting)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|interpro:IPR044865|rcsb pdb:3AIH|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-37493N	ensembl:ENSG00000102910(gene)|ensembl:ENST00000285737(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006625"(protein targeting to peroxisome)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008233"(peptidase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0019899"(enzyme binding)|go:"GO:0031998"(regulation of fatty acid beta-oxidation)|interpro:IPR003111(Peptidase S16, lon N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR004815(Peptidase S16, ATP-dependent protease La)|interpro:IPR008268(Peptidase S16, active site)|interpro:IPR008269(Peptidase S16, lon C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR015947(PUA-like)|interpro:IPR020568|interpro:IPR027065|interpro:IPR027417|interpro:IPR027501|reactome:R-HSA-390471|reactome:R-HSA-9033241|refseq:NP_001287877.1|refseq:NP_113678.2|genbank_nucl_gi:74727668(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:Ntc3geE7th+rBeIp0MxuUuu/28Y9606	rogid:WyZglDz2aZOpnRVtWTrAf62G0pA9606	rigid:FcYEMxkq8y8FMJVfyQv6EbOBC5w	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q13438	uniprotkb:Q9UBV2	intact:EBI-725454|intact:EBI-1174342|uniprotkb:A6NDD1|uniprotkb:A6NFR7|uniprotkb:A6NLB2|uniprotkb:A8K5Q9|uniprotkb:B4DPX1|uniprotkb:B4E1I6|uniprotkb:E7ENT8|uniprotkb:F8VUH2|uniprotkb:O00579|uniprotkb:Q6IBL2|uniprotkb:Q8IZ58|uniprotkb:Q9BW99|uniprotkb:B4DE28|ensembl:ENSP00000318165|uniprotkb:E7EW91|uniprotkb:G3XA88	intact:EBI-358766|uniprotkb:Q6UWT6|uniprotkb:Q9P1T9|uniprotkb:Q9UHK7|ensembl:ENSP00000337053	psi-mi:os9_human(display_long)|uniprotkb:OS9(gene name)|psi-mi:OS9(display_short)|uniprotkb:Amplified in osteosarcoma 9(gene name synonym)	psi-mi:se1l1_human(display_long)|uniprotkb:SEL1L(gene name)|psi-mi:SEL1L(display_short)|uniprotkb:TSA305(gene name synonym)|uniprotkb:UNQ128/PRO1063(orf name)|uniprotkb:Suppressor of lin-12-like protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771036|imex:IM-28143-102	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006803.1|refseq:NP_001017956.1|refseq:NP_001017957.1|refseq:NP_001017958.1|refseq:NP_001248349.1|refseq:NP_001248350.1|refseq:NP_001248351.1|refseq:NP_001248352.1|ensembl:ENSG00000135506(gene)|ensembl:ENST00000315970(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0002020"(protease binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006605"(protein targeting)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|interpro:IPR044865|rcsb pdb:3AIH|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-37493N	refseq:NP_001231913.1|refseq:NP_005056.3|ensembl:ENSG00000071537(gene)|ensembl:ENST00000336735(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0050821"(protein stabilization)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|mint:Q9UBV2|reactome:R-HSA-1912420|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-46259N|genbank_nucl_gi:62512184(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:Ntc3geE7th+rBeIp0MxuUuu/28Y9606	rogid:eufE+8nfcHK8CDl+AQ5G+3NtL+09606	rigid:FcYEMxkq8y8FMJVfyQv6EbOBC5w	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q13438	uniprotkb:Q92820	intact:EBI-725454|intact:EBI-1174342|uniprotkb:A6NDD1|uniprotkb:A6NFR7|uniprotkb:A6NLB2|uniprotkb:A8K5Q9|uniprotkb:B4DPX1|uniprotkb:B4E1I6|uniprotkb:E7ENT8|uniprotkb:F8VUH2|uniprotkb:O00579|uniprotkb:Q6IBL2|uniprotkb:Q8IZ58|uniprotkb:Q9BW99|uniprotkb:B4DE28|ensembl:ENSP00000318165|uniprotkb:E7EW91|uniprotkb:G3XA88	intact:EBI-3045534|ensembl:ENSP00000260118	psi-mi:os9_human(display_long)|uniprotkb:OS9(gene name)|psi-mi:OS9(display_short)|uniprotkb:Amplified in osteosarcoma 9(gene name synonym)	psi-mi:ggh_human(display_long)|uniprotkb:GGH(gene name)|psi-mi:GGH(display_short)|uniprotkb:Conjugase(gene name synonym)|uniprotkb:GH(gene name synonym)|uniprotkb:Gamma-Glu-X carboxypeptidase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771036|imex:IM-28143-102	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006803.1|refseq:NP_001017956.1|refseq:NP_001017957.1|refseq:NP_001017958.1|refseq:NP_001248349.1|refseq:NP_001248350.1|refseq:NP_001248351.1|refseq:NP_001248352.1|ensembl:ENSG00000135506(gene)|ensembl:ENST00000315970(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0002020"(protease binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006605"(protein targeting)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|interpro:IPR044865|rcsb pdb:3AIH|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-37493N	ensembl:ENSG00000137563(gene)|ensembl:ENST00000260118(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0008238"(exopeptidase activity)|go:"GO:0008242"(omega peptidase activity)|go:"GO:0010043"(response to zinc ion)|go:"GO:0032868"(response to insulin)|go:"GO:0034722"(gamma-glutamyl-peptidase activity)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0045471"(response to ethanol)|go:"GO:0046900"(tetrahydrofolylpolyglutamate metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070500"(poly-gamma-glutamate metabolic process)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR011697(Peptidase C26)|interpro:IPR015527(Peptidase C26, gamma-glutamyl hydrolase)|interpro:IPR029062|mint:Q92820|rcsb pdb:1L9X|reactome:R-HSA-6798695|refseq:NP_003869.1|genbank_nucl_gi:6016127(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:Ntc3geE7th+rBeIp0MxuUuu/28Y9606	rogid:QjPbv+fLXWnf6gmW2PsXVuyatR49606	rigid:FcYEMxkq8y8FMJVfyQv6EbOBC5w	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q13438	uniprotkb:P50454	intact:EBI-725454|intact:EBI-1174342|uniprotkb:A6NDD1|uniprotkb:A6NFR7|uniprotkb:A6NLB2|uniprotkb:A8K5Q9|uniprotkb:B4DPX1|uniprotkb:B4E1I6|uniprotkb:E7ENT8|uniprotkb:F8VUH2|uniprotkb:O00579|uniprotkb:Q6IBL2|uniprotkb:Q8IZ58|uniprotkb:Q9BW99|uniprotkb:B4DE28|ensembl:ENSP00000318165|uniprotkb:E7EW91|uniprotkb:G3XA88	intact:EBI-350723|uniprotkb:P29043|uniprotkb:Q5XPB4|uniprotkb:Q6NSJ6|uniprotkb:Q8IY96|uniprotkb:Q9NP88|uniprotkb:B3KVJ3|ensembl:ENSP00000350894|ensembl:ENSP00000434412|ensembl:ENSP00000434657	psi-mi:os9_human(display_long)|uniprotkb:OS9(gene name)|psi-mi:OS9(display_short)|uniprotkb:Amplified in osteosarcoma 9(gene name synonym)	psi-mi:serph_human(display_long)|uniprotkb:SERPINH1(gene name)|psi-mi:SERPINH1(display_short)|uniprotkb:CBP2(gene name synonym)|uniprotkb:Collagen-binding protein(gene name synonym)|uniprotkb:47 kDa heat shock protein(gene name synonym)|uniprotkb:Rheumatoid arthritis-related antigen RA-A47(gene name synonym)|uniprotkb:Arsenic-transactivated protein 3(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 14 protein(gene name synonym)|uniprotkb:CBP1(gene name synonym)|uniprotkb:HSP47(gene name synonym)|uniprotkb:SERPINH2(gene name synonym)|uniprotkb:PIG14(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771036|imex:IM-28143-102	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006803.1|refseq:NP_001017956.1|refseq:NP_001017957.1|refseq:NP_001017958.1|refseq:NP_001248349.1|refseq:NP_001248350.1|refseq:NP_001248351.1|refseq:NP_001248352.1|ensembl:ENSG00000135506(gene)|ensembl:ENST00000315970(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0002020"(protease binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006605"(protein targeting)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|interpro:IPR044865|rcsb pdb:3AIH|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-37493N	refseq:NP_001193943.1|refseq:NP_001226.2|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0032964"(collagen biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR033547|interpro:IPR033830|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P50454|reactome:R-HSA-1650814|ensembl:ENSG00000149257(gene)|ensembl:ENST00000358171(transcript)|ensembl:ENST00000524558(transcript)|ensembl:ENST00000533603(transcript)|go:"GO:0003433"(chondrocyte development involved in endochondral bone morphogenesis)|refseq:XP_011543629.1|genbank_nucl_gi:20141241(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:Ntc3geE7th+rBeIp0MxuUuu/28Y9606	rogid:cO3NR2hb0NyOs99Sq1aODePlDR09606	rigid:FcYEMxkq8y8FMJVfyQv6EbOBC5w	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q13438	uniprotkb:P04843	intact:EBI-725454|intact:EBI-1174342|uniprotkb:A6NDD1|uniprotkb:A6NFR7|uniprotkb:A6NLB2|uniprotkb:A8K5Q9|uniprotkb:B4DPX1|uniprotkb:B4E1I6|uniprotkb:E7ENT8|uniprotkb:F8VUH2|uniprotkb:O00579|uniprotkb:Q6IBL2|uniprotkb:Q8IZ58|uniprotkb:Q9BW99|uniprotkb:B4DE28|ensembl:ENSP00000318165|uniprotkb:E7EW91|uniprotkb:G3XA88	intact:EBI-355963|ensembl:ENSP00000296255|uniprotkb:D3DNB6|uniprotkb:Q68DT1|uniprotkb:B2R5Z0	psi-mi:os9_human(display_long)|uniprotkb:OS9(gene name)|psi-mi:OS9(display_short)|uniprotkb:Amplified in osteosarcoma 9(gene name synonym)	psi-mi:rpn1_human(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit(gene name synonym)|uniprotkb:Ribophorin-1(gene name synonym)|uniprotkb:Ribophorin I(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771036|imex:IM-28143-102	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006803.1|refseq:NP_001017956.1|refseq:NP_001017957.1|refseq:NP_001017958.1|refseq:NP_001248349.1|refseq:NP_001248350.1|refseq:NP_001248351.1|refseq:NP_001248352.1|ensembl:ENSG00000135506(gene)|ensembl:ENST00000315970(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0002020"(protease binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006605"(protein targeting)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|interpro:IPR044865|rcsb pdb:3AIH|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-37493N	ensembl:ENSG00000163902(gene)|ensembl:ENST00000296255(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0042470"(melanosome)|interpro:IPR007676(Ribophorin I)|mint:P04843|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-9694548|go:"GO:0006464"(cellular protein modification process)|refseq:NP_002941.1|dip:DIP-38152N|genbank_nucl_gi:132559(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:Ntc3geE7th+rBeIp0MxuUuu/28Y9606	rogid:rvQThNB/dCCNR9+IDssZo1qgZUE9606	rigid:FcYEMxkq8y8FMJVfyQv6EbOBC5w	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q13438	uniprotkb:P14625	intact:EBI-725454|intact:EBI-1174342|uniprotkb:A6NDD1|uniprotkb:A6NFR7|uniprotkb:A6NLB2|uniprotkb:A8K5Q9|uniprotkb:B4DPX1|uniprotkb:B4E1I6|uniprotkb:E7ENT8|uniprotkb:F8VUH2|uniprotkb:O00579|uniprotkb:Q6IBL2|uniprotkb:Q8IZ58|uniprotkb:Q9BW99|uniprotkb:B4DE28|ensembl:ENSP00000318165|uniprotkb:E7EW91|uniprotkb:G3XA88	intact:EBI-359129|uniprotkb:Q96A97|ensembl:ENSP00000299767	psi-mi:os9_human(display_long)|uniprotkb:OS9(gene name)|psi-mi:OS9(display_short)|uniprotkb:Amplified in osteosarcoma 9(gene name synonym)	psi-mi:enpl_human(display_long)|uniprotkb:HSP90B1(gene name)|psi-mi:HSP90B1(display_short)|uniprotkb:TRA1(gene name synonym)|uniprotkb:Heat shock protein 90 kDa beta member 1(gene name synonym)|uniprotkb:94 kDa glucose-regulated protein(gene name synonym)|uniprotkb:GRP94(gene name synonym)|uniprotkb:gp96 homolog(gene name synonym)|uniprotkb:Tumor rejection antigen 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771036|imex:IM-28143-102	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006803.1|refseq:NP_001017956.1|refseq:NP_001017957.1|refseq:NP_001017958.1|refseq:NP_001248349.1|refseq:NP_001248350.1|refseq:NP_001248351.1|refseq:NP_001248352.1|ensembl:ENSG00000135506(gene)|ensembl:ENST00000315970(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0002020"(protease binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006605"(protein targeting)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|interpro:IPR044865|rcsb pdb:3AIH|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-37493N	refseq:NP_003290.1|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051208"(sequestering of calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071682"(endocytic vesicle lumen)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P14625|rcsb pdb:4NH9|reactome:R-HSA-1679131|reactome:R-HSA-3000480|reactome:R-HSA-381183|reactome:R-HSA-381426|reactome:R-HSA-6785807|reactome:R-HSA-8957275|ensembl:ENSG00000166598(gene)|ensembl:ENST00000299767(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031247"(actin rod assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|dip:DIP-36060N|genbank_nucl_gi:119360(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:Ntc3geE7th+rBeIp0MxuUuu/28Y9606	rogid:m5CdlplqVyMUWYe75aKDuMzztMY9606	rigid:FcYEMxkq8y8FMJVfyQv6EbOBC5w	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NPA0	uniprotkb:Q8N4V1	intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5	intact:EBI-6163737|ensembl:ENSP00000306220|ensembl:ENSP00000505226|uniprotkb:B2R625|uniprotkb:B4DIY3|uniprotkb:D3DWG7|uniprotkb:Q5JPP7	psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name)	psi-mi:emc5_human(display_long)|uniprotkb:MMGT1(gene name)|psi-mi:MMGT1(display_short)|uniprotkb:TMEM32(gene name synonym)|uniprotkb:Transmembrane protein 32(gene name synonym)|uniprotkb:EMC5(gene name synonym)|uniprotkb:Membrane magnesium transporter 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771477|imex:IM-28143-106	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1	go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-5223345|ensembl:ENSG00000169446(gene)|ensembl:ENST00000305963(transcript)|ensembl:ENST00000679621(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|refseq:NP_775741.1|refseq:NP_001316929.1|genbank_nucl_gi:74751006(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606	rogid:Kq+VEYt+fwoOsEfcgZ1K1vkFFN49606	rigid:sIlfff7CNfyFyIFsCaqNn22U/CE	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NPA0	uniprotkb:Q5UCC4	intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5	intact:EBI-11284388|uniprotkb:Q5UCC6|uniprotkb:Q69YT5|uniprotkb:Q6UWP3|uniprotkb:Q86YL4|uniprotkb:Q8N541|ensembl:ENSP00000334037	psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name)	psi-mi:emc10_human(display_long)|uniprotkb:EMC10(gene name)|psi-mi:EMC10(display_short)|uniprotkb:C19orf63(gene name synonym)|uniprotkb:Hematopoietic signal peptide-containing membrane domain-containing protein 1(gene name synonym)|uniprotkb:INM02(gene name synonym)|uniprotkb:UNQ764/PRO1556(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771477|imex:IM-28143-106	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1	refseq:NP_778233.4|refseq:NP_996261.1|ensembl:ENSG00000161671(gene)|ensembl:ENST00000334976(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005576"(extracellular region)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR029615|mint:Q5UCC4|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|genbank_nucl_gi:89886466(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606	rogid:NEJjkw5uEJnzNUW7MkZIm/ELpA89606	rigid:sIlfff7CNfyFyIFsCaqNn22U/CE	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NPA0	uniprotkb:Q8N766	intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5	intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62	psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name)	psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771477|imex:IM-28143-106	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1	go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1|genbank_nucl_gi:74751081(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606	rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606	rigid:sIlfff7CNfyFyIFsCaqNn22U/CE	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NPA0	uniprotkb:Q9BV81	intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5	intact:EBI-2820492|ensembl:ENSP00000248378|ensembl:ENSP00000380322	psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name)	psi-mi:emc6_human(display_long)|uniprotkb:EMC6(gene name)|psi-mi:EMC6(display_short)|uniprotkb:TMEM93(gene name synonym)|uniprotkb:Transmembrane protein 93(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771477|imex:IM-28143-106	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1	refseq:NP_001014764.1|refseq:NP_112588.1|ensembl:ENSG00000127774(gene)|ensembl:ENST00000248378(transcript)|ensembl:ENST00000397133(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0097631"(integral component of omegasome membrane)|interpro:IPR008504(Protein of unknown function DUF786)|interpro:IPR029008|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|go:"GO:0072546"(EMC complex)|genbank_nucl_gi:74733294(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606	rogid:GPnTCJqAA2eIiiP17pgtIhGnpsA9606	rigid:sIlfff7CNfyFyIFsCaqNn22U/CE	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NPA0	uniprotkb:Q9P0I2	intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5	intact:EBI-1054670|uniprotkb:Q53GH8|uniprotkb:Q6ZMC2|uniprotkb:B2R4Z9|ensembl:ENSP00000245046	psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name)	psi-mi:emc3_human(display_long)|uniprotkb:EMC3(gene name)|psi-mi:EMC3(display_short)|uniprotkb:TMEM111(gene name synonym)|uniprotkb:Transmembrane protein 111(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771477|imex:IM-28143-106	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1	refseq:NP_060917.1|ensembl:ENSG00000125037(gene)|ensembl:ENST00000245046(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008568(Protein of unknown function DUF850, transmembrane eukaryotic)|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-8980692|genbank_nucl_gi:71153383(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606	rogid:VbIl0nFhcDMIPTxmBclaIMtbVU09606	rigid:sIlfff7CNfyFyIFsCaqNn22U/CE	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NPA0	uniprotkb:Q15006	intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5	intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853	psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name)	psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771477|imex:IM-28143-106	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1	refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|genbank_nucl_gi:3183217(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606	rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606	rigid:sIlfff7CNfyFyIFsCaqNn22U/CE	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NPA0	uniprotkb:O43402	intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5	intact:EBI-741841|ensembl:ENSP00000253457|uniprotkb:C9JB21	psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name)	psi-mi:emc8_human(display_long)|uniprotkb:EMC8(gene name)|psi-mi:EMC8(display_short)|uniprotkb:C16orf2(gene name synonym)|uniprotkb:C16orf4(gene name synonym)|uniprotkb:COX4AL(gene name synonym)|uniprotkb:COX4NB(gene name synonym)|uniprotkb:FAM158B(gene name synonym)|uniprotkb:NOC4(gene name synonym)|uniprotkb:Neighbor of COX4(gene name synonym)|uniprotkb:Protein FAM158B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771477|imex:IM-28143-106	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1	refseq:NP_006058.1|ensembl:ENSG00000131148(gene)|ensembl:ENST00000253457(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6WW7|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_001135760.1|genbank_nucl_gi:18202040(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606	rogid:cGQFR1ZU2L/KgikqLELVUzplhTU9606	rigid:sIlfff7CNfyFyIFsCaqNn22U/CE	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NPA0	uniprotkb:Q9Y3B6	intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5	intact:EBI-748366|uniprotkb:Q9BUM3|uniprotkb:D3DS60|ensembl:ENSP00000216799|ensembl:ENSP00000403210|ensembl:ENSP00000494976|ensembl:ENSP00000495623	psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name)	psi-mi:emc9_human(display_long)|uniprotkb:EMC9(gene name)|psi-mi:EMC9(display_short)|uniprotkb:C14orf122(gene name synonym)|uniprotkb:FAM158A(gene name synonym)|uniprotkb:Protein FAM158A(gene name synonym)|uniprotkb:CGI-112(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771477|imex:IM-28143-106	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1	refseq:NP_057133.2|refseq:XP_005267778.1|ensembl:ENSG00000100908(gene)|ensembl:ENSG00000285377(gene)|ensembl:ENST00000216799(transcript)|ensembl:ENST00000419198(transcript)|ensembl:ENST00000642147(transcript)|ensembl:ENST00000646772(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6Y4L|rcsb pdb:6Z3W|genbank_nucl_gi:116241305(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606	rogid:ZMbNxmOKb2r2KzWdB5JF/kGPSaU9606	rigid:sIlfff7CNfyFyIFsCaqNn22U/CE	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NPA0	uniprotkb:Q5J8M3	intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5	intact:EBI-2814031|uniprotkb:Q9P0T9|uniprotkb:Q96KX9|uniprotkb:B4DJQ4|uniprotkb:Q9BUI5|uniprotkb:A8K3A9|ensembl:ENSP00000267750	psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name)	psi-mi:emc4_human(display_long)|uniprotkb:EMC4(gene name)|psi-mi:EMC4(display_short)|uniprotkb:Cell proliferation-inducing gene 17 protein(gene name synonym)|uniprotkb:TMEM85(gene name synonym)|uniprotkb:Transmembrane protein 85(gene name synonym)|uniprotkb:HSPC184(orf name)|uniprotkb:PIG17(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771477|imex:IM-28143-106	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1	refseq:NP_001273349.1|refseq:NP_057538.1|ensembl:ENSG00000128463(gene)|ensembl:ENST00000267750(transcript)|go:"GO:0006915"(apoptotic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR009445(Protein of unknown function DUF1077)|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|go:"GO:0016021"(integral component of membrane)|genbank_nucl_gi:115502869(identity)	-	-	-	figure legend:TableS3A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606	rogid:b6qUbq3mJhmXTtZFctD6xd4E1jQ9606	rigid:sIlfff7CNfyFyIFsCaqNn22U/CE	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96DZ1	uniprotkb:Q9GZP9	intact:EBI-1023677|uniprotkb:O95901|uniprotkb:Q6UWN7|uniprotkb:Q9NUY7|uniprotkb:Q9UQL4|uniprotkb:B2RDB4|ensembl:ENSP00000185150|uniprotkb:B5MC72	intact:EBI-7962814|uniprotkb:Q9Y3A7|intact:MINT-3065126|ensembl:ENSP00000158771	psi-mi:erlec_human(display_long)|uniprotkb:ER lectin(gene name synonym)|uniprotkb:ERLEC1(gene name)|psi-mi:ERLEC1(display_short)|uniprotkb:XTP3TPB(gene name synonym)|uniprotkb:UNQ1878/PRO4321(orf name)|uniprotkb:C2orf30(gene name synonym)|uniprotkb:XTP3-transactivated gene B protein(gene name synonym)	psi-mi:derl2_human(display_long)|uniprotkb:DERL2(gene name)|psi-mi:DERL2(display_short)|uniprotkb:DER2(gene name synonym)|uniprotkb:FLANA(gene name synonym)|uniprotkb:CGI-101(orf name)|uniprotkb:SBBI53(orf name)|uniprotkb:Der1-like protein 2(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 2(gene name synonym)|uniprotkb:F-LAN-1(gene name synonym)|uniprotkb:F-LANa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25769890|imex:IM-28143-48	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120870.1|refseq:NP_056516.2|ensembl:ENSG00000068912(gene)|ensembl:ENST00000185150(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR044865|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|refseq:NP_001120869.1	refseq:NP_001291708.1|refseq:NP_057125.2|ensembl:ENSG00000072849(gene)|ensembl:ENST00000158771(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0001967"(suckling behavior)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|genbank_nucl_gi:50400648(identity)	-	-	comment:mint|function:"Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate. In contrast to DERL1, it is not involved in the degradation of MHC class I heavy chains following infection by cytomegaloviruses. May play a role in cell proliferation"	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:eBOyI1TfCgExBrXLxSwlUZ05NXs9606	rogid:hoayS/Xn9+pq/C61NYRu/1aOm6s9606	rigid:bJrxHziBBdGXYnqj1ugE9BOmjmE	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96DZ1	uniprotkb:Q9UBU6	intact:EBI-1023677|uniprotkb:O95901|uniprotkb:Q6UWN7|uniprotkb:Q9NUY7|uniprotkb:Q9UQL4|uniprotkb:B2RDB4|ensembl:ENSP00000185150|uniprotkb:B5MC72	intact:EBI-6309101|intact:EBI-28967558|ensembl:ENSP00000259963|uniprotkb:B2R725	psi-mi:erlec_human(display_long)|uniprotkb:ER lectin(gene name synonym)|uniprotkb:ERLEC1(gene name)|psi-mi:ERLEC1(display_short)|uniprotkb:XTP3TPB(gene name synonym)|uniprotkb:UNQ1878/PRO4321(orf name)|uniprotkb:C2orf30(gene name synonym)|uniprotkb:XTP3-transactivated gene B protein(gene name synonym)	psi-mi:fa8a1_human(display_long)|uniprotkb:FAM8A1(gene name)|psi-mi:FAM8A1(display_short)|uniprotkb:AHCP(gene name synonym)|uniprotkb:Autosomal highly conserved protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25769890|imex:IM-28143-48	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120870.1|refseq:NP_056516.2|ensembl:ENSG00000068912(gene)|ensembl:ENST00000185150(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR044865|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|refseq:NP_001120869.1	ensembl:ENSP00000259963|ensembl:ENSG00000137414(gene)|ensembl:ENST00000259963(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|interpro:IPR010432(RDD)|interpro:IPR039871|refseq:NP_057339.1|genbank_nucl_gi:74753230(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:eBOyI1TfCgExBrXLxSwlUZ05NXs9606	rogid:0HV6qye10bMGdnt9CiGztIacrHM9606	rigid:bJrxHziBBdGXYnqj1ugE9BOmjmE	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96DZ1	uniprotkb:Q9H3G5	intact:EBI-1023677|uniprotkb:O95901|uniprotkb:Q6UWN7|uniprotkb:Q9NUY7|uniprotkb:Q9UQL4|uniprotkb:B2RDB4|ensembl:ENSP00000185150|uniprotkb:B5MC72	intact:EBI-357542|uniprotkb:Q6UX20|uniprotkb:Q8NBL7|uniprotkb:Q96AR7|uniprotkb:Q9HB41|ensembl:ENSP00000265394|ensembl:ENSP00000379572|ensembl:ENSP00000387164|intact:EBI-1058665|uniprotkb:A4D1A4	psi-mi:erlec_human(display_long)|uniprotkb:ER lectin(gene name synonym)|uniprotkb:ERLEC1(gene name)|psi-mi:ERLEC1(display_short)|uniprotkb:XTP3TPB(gene name synonym)|uniprotkb:UNQ1878/PRO4321(orf name)|uniprotkb:C2orf30(gene name synonym)|uniprotkb:XTP3-transactivated gene B protein(gene name synonym)	psi-mi:cpvl_human(display_long)|uniprotkb:CPVL(gene name)|psi-mi:CPVL(display_short)|uniprotkb:VLP(gene name synonym)|uniprotkb:UNQ197/PRO223(orf name)|uniprotkb:PSEC0124(orf name)|uniprotkb:Carboxypeptidase, vitellogenic-like(gene name synonym)|uniprotkb:Vitellogenic carboxypeptidase-like protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25769890|imex:IM-28143-48	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120870.1|refseq:NP_056516.2|ensembl:ENSG00000068912(gene)|ensembl:ENST00000185150(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR044865|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|refseq:NP_001120869.1	ensembl:ENSG00000106066(gene)|ensembl:ENST00000265394(transcript)|ensembl:ENST00000396276(transcript)|ensembl:ENST00000409850(transcript)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR029058|mint:Q9H3G5|refseq:NP_061902.2|refseq:NP_112601.3|refseq:XP_011513739.1|refseq:NP_001334981.1|refseq:NP_001334983.1|genbank_nucl_gi:67476930(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:eBOyI1TfCgExBrXLxSwlUZ05NXs9606	rogid:antgab61u6D+KmbopQeowXqSqWQ9606	rigid:bJrxHziBBdGXYnqj1ugE9BOmjmE	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96DZ1	uniprotkb:Q9UBV2	intact:EBI-1023677|uniprotkb:O95901|uniprotkb:Q6UWN7|uniprotkb:Q9NUY7|uniprotkb:Q9UQL4|uniprotkb:B2RDB4|ensembl:ENSP00000185150|uniprotkb:B5MC72	intact:EBI-358766|uniprotkb:Q6UWT6|uniprotkb:Q9P1T9|uniprotkb:Q9UHK7|ensembl:ENSP00000337053	psi-mi:erlec_human(display_long)|uniprotkb:ER lectin(gene name synonym)|uniprotkb:ERLEC1(gene name)|psi-mi:ERLEC1(display_short)|uniprotkb:XTP3TPB(gene name synonym)|uniprotkb:UNQ1878/PRO4321(orf name)|uniprotkb:C2orf30(gene name synonym)|uniprotkb:XTP3-transactivated gene B protein(gene name synonym)	psi-mi:se1l1_human(display_long)|uniprotkb:SEL1L(gene name)|psi-mi:SEL1L(display_short)|uniprotkb:TSA305(gene name synonym)|uniprotkb:UNQ128/PRO1063(orf name)|uniprotkb:Suppressor of lin-12-like protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25769890|imex:IM-28143-48	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120870.1|refseq:NP_056516.2|ensembl:ENSG00000068912(gene)|ensembl:ENST00000185150(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR044865|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|refseq:NP_001120869.1	refseq:NP_001231913.1|refseq:NP_005056.3|ensembl:ENSG00000071537(gene)|ensembl:ENST00000336735(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0050821"(protein stabilization)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|mint:Q9UBV2|reactome:R-HSA-1912420|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-46259N|genbank_nucl_gi:62512184(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:eBOyI1TfCgExBrXLxSwlUZ05NXs9606	rogid:eufE+8nfcHK8CDl+AQ5G+3NtL+09606	rigid:bJrxHziBBdGXYnqj1ugE9BOmjmE	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96DZ1	uniprotkb:Q9Y385	intact:EBI-1023677|uniprotkb:O95901|uniprotkb:Q6UWN7|uniprotkb:Q9NUY7|uniprotkb:Q9UQL4|uniprotkb:B2RDB4|ensembl:ENSP00000185150|uniprotkb:B5MC72	intact:EBI-988826|uniprotkb:Q5W0N4|uniprotkb:Q9BZ32|uniprotkb:Q9NQL3|uniprotkb:Q9NY66|uniprotkb:Q9P011|uniprotkb:Q9P0S0|uniprotkb:Q9UF10|ensembl:ENSP00000451261|uniprotkb:A8K3F9|uniprotkb:Q53F25	psi-mi:erlec_human(display_long)|uniprotkb:ER lectin(gene name synonym)|uniprotkb:ERLEC1(gene name)|psi-mi:ERLEC1(display_short)|uniprotkb:XTP3TPB(gene name synonym)|uniprotkb:UNQ1878/PRO4321(orf name)|uniprotkb:C2orf30(gene name synonym)|uniprotkb:XTP3-transactivated gene B protein(gene name synonym)	psi-mi:ub2j1_human(display_long)|uniprotkb:Non-canonical ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:Yeast ubiquitin-conjugating enzyme UBC6 homolog E(gene name synonym)|uniprotkb:UBE2J1(gene name)|psi-mi:UBE2J1(display_short)|uniprotkb:NCUBE1(gene name synonym)|uniprotkb:CGI-76(orf name)|uniprotkb:HSPC153(orf name)|uniprotkb:HSPC205(orf name)|uniprotkb:E2 ubiquitin-conjugating enzyme J1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25769890|imex:IM-28143-48	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120870.1|refseq:NP_056516.2|ensembl:ENSG00000068912(gene)|ensembl:ENST00000185150(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR044865|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|refseq:NP_001120869.1	go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|reactome:R-HSA-983168|ensembl:ENSG00000198833(gene)|ensembl:ENST00000435041(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007286"(spermatid development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:NP_057105.2|dip:DIP-45598N|genbank_nucl_gi:52000881(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:eBOyI1TfCgExBrXLxSwlUZ05NXs9606	rogid:nc3+V3Qxy1ZDhTWgTPLakJukxPM9606	rigid:bJrxHziBBdGXYnqj1ugE9BOmjmE	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96DZ1	uniprotkb:P60604	intact:EBI-1023677|uniprotkb:O95901|uniprotkb:Q6UWN7|uniprotkb:Q9NUY7|uniprotkb:Q9UQL4|uniprotkb:B2RDB4|ensembl:ENSP00000185150|uniprotkb:B5MC72	intact:EBI-1051028|uniprotkb:P56554|uniprotkb:A8K3L4|uniprotkb:D3DSL7|uniprotkb:A6NMQ7|ensembl:ENSP00000338348	psi-mi:erlec_human(display_long)|uniprotkb:ER lectin(gene name synonym)|uniprotkb:ERLEC1(gene name)|psi-mi:ERLEC1(display_short)|uniprotkb:XTP3TPB(gene name synonym)|uniprotkb:UNQ1878/PRO4321(orf name)|uniprotkb:C2orf30(gene name synonym)|uniprotkb:XTP3-transactivated gene B protein(gene name synonym)	psi-mi:ub2g2_human(display_long)|uniprotkb:Ubiquitin-protein ligase G2(gene name synonym)|uniprotkb:Ubiquitin carrier protein G2(gene name synonym)|uniprotkb:UBE2G2(gene name)|psi-mi:UBE2G2(display_short)|uniprotkb:E2 ubiquitin-conjugating enzyme G2(gene name synonym)|uniprotkb:UBC7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25769890|imex:IM-28143-48	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120870.1|refseq:NP_056516.2|ensembl:ENSG00000068912(gene)|ensembl:ENST00000185150(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR044865|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|refseq:NP_001120869.1	refseq:NP_001189418.1|refseq:NP_003334.2|refseq:NP_872630.1|refseq:XP_016883958.1|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2CYX|rcsb pdb:2KLY|rcsb pdb:2LXP|rcsb pdb:3H8K|rcsb pdb:4LAD|reactome:R-HSA-8866652|reactome:R-HSA-983168|ensembl:ENSG00000184787(gene)|ensembl:ENST00000345496(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-50750N|genbank_nucl_gi:33359701(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:eBOyI1TfCgExBrXLxSwlUZ05NXs9606	rogid:Q/uslqX/WH/SxKEPYeMmU9CjTBI9606	rigid:bJrxHziBBdGXYnqj1ugE9BOmjmE	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96DZ1	uniprotkb:Q13438	intact:EBI-1023677|uniprotkb:O95901|uniprotkb:Q6UWN7|uniprotkb:Q9NUY7|uniprotkb:Q9UQL4|uniprotkb:B2RDB4|ensembl:ENSP00000185150|uniprotkb:B5MC72	intact:EBI-725454|intact:EBI-1174342|uniprotkb:A6NDD1|uniprotkb:A6NFR7|uniprotkb:A6NLB2|uniprotkb:A8K5Q9|uniprotkb:B4DPX1|uniprotkb:B4E1I6|uniprotkb:E7ENT8|uniprotkb:F8VUH2|uniprotkb:O00579|uniprotkb:Q6IBL2|uniprotkb:Q8IZ58|uniprotkb:Q9BW99|uniprotkb:B4DE28|ensembl:ENSP00000318165|uniprotkb:E7EW91|uniprotkb:G3XA88	psi-mi:erlec_human(display_long)|uniprotkb:ER lectin(gene name synonym)|uniprotkb:ERLEC1(gene name)|psi-mi:ERLEC1(display_short)|uniprotkb:XTP3TPB(gene name synonym)|uniprotkb:UNQ1878/PRO4321(orf name)|uniprotkb:C2orf30(gene name synonym)|uniprotkb:XTP3-transactivated gene B protein(gene name synonym)	psi-mi:os9_human(display_long)|uniprotkb:OS9(gene name)|psi-mi:OS9(display_short)|uniprotkb:Amplified in osteosarcoma 9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25769890|imex:IM-28143-48	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120870.1|refseq:NP_056516.2|ensembl:ENSG00000068912(gene)|ensembl:ENST00000185150(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR044865|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|refseq:NP_001120869.1	refseq:NP_006803.1|refseq:NP_001017956.1|refseq:NP_001017957.1|refseq:NP_001017958.1|refseq:NP_001248349.1|refseq:NP_001248350.1|refseq:NP_001248351.1|refseq:NP_001248352.1|ensembl:ENSG00000135506(gene)|ensembl:ENST00000315970(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0002020"(protease binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006605"(protein targeting)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|interpro:IPR044865|rcsb pdb:3AIH|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-37493N|genbank_nucl_gi:3024310(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:eBOyI1TfCgExBrXLxSwlUZ05NXs9606	rogid:Ntc3geE7th+rBeIp0MxuUuu/28Y9606	rigid:bJrxHziBBdGXYnqj1ugE9BOmjmE	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96DZ1	uniprotkb:Q86TM6	intact:EBI-1023677|uniprotkb:O95901|uniprotkb:Q6UWN7|uniprotkb:Q9NUY7|uniprotkb:Q9UQL4|uniprotkb:B2RDB4|ensembl:ENSP00000185150|uniprotkb:B5MC72	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	psi-mi:erlec_human(display_long)|uniprotkb:ER lectin(gene name synonym)|uniprotkb:ERLEC1(gene name)|psi-mi:ERLEC1(display_short)|uniprotkb:XTP3TPB(gene name synonym)|uniprotkb:UNQ1878/PRO4321(orf name)|uniprotkb:C2orf30(gene name synonym)|uniprotkb:XTP3-transactivated gene B protein(gene name synonym)	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25769890|imex:IM-28143-48	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120870.1|refseq:NP_056516.2|ensembl:ENSG00000068912(gene)|ensembl:ENST00000185150(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR044865|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|refseq:NP_001120869.1	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032|genbank_nucl_gi:27436925(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:eBOyI1TfCgExBrXLxSwlUZ05NXs9606	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rigid:bJrxHziBBdGXYnqj1ugE9BOmjmE	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96DZ1	uniprotkb:Q5K4L6	intact:EBI-1023677|uniprotkb:O95901|uniprotkb:Q6UWN7|uniprotkb:Q9NUY7|uniprotkb:Q9UQL4|uniprotkb:B2RDB4|ensembl:ENSP00000185150|uniprotkb:B5MC72	intact:EBI-11733324|ensembl:ENSP00000485061|ensembl:ENSP00000485585|uniprotkb:Q5VUQ7|uniprotkb:Q5VUQ8|uniprotkb:Q5VUR3|uniprotkb:Q6ZV16|uniprotkb:Q8N2X7|uniprotkb:Q8TEJ0|uniprotkb:Q96SW5|uniprotkb:Q9BTJ5|uniprotkb:Q9BTY5	psi-mi:erlec_human(display_long)|uniprotkb:ER lectin(gene name synonym)|uniprotkb:ERLEC1(gene name)|psi-mi:ERLEC1(display_short)|uniprotkb:XTP3TPB(gene name synonym)|uniprotkb:UNQ1878/PRO4321(orf name)|uniprotkb:C2orf30(gene name synonym)|uniprotkb:XTP3-transactivated gene B protein(gene name synonym)	psi-mi:s27a3_human(display_long)|uniprotkb:SLC27A3(gene name)|psi-mi:SLC27A3(display_short)|uniprotkb:ACSVL3(gene name synonym)|uniprotkb:FATP3(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Very long-chain acyl-CoA synthetase homolog 3(gene name synonym)|uniprotkb:PSEC0067(orf name)|uniprotkb:UNQ367/PRO703(orf name)|uniprotkb:Long-chain fatty acid transport protein 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25769890|imex:IM-28143-48	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001120870.1|refseq:NP_056516.2|ensembl:ENSG00000068912(gene)|ensembl:ENST00000185150(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR044865|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|refseq:NP_001120869.1	ensembl:ENSG00000143554(gene)|ensembl:ENSG00000263163(gene)|ensembl:ENST00000623839(transcript)|ensembl:ENST00000624995(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0047676"(arachidonate-CoA ligase activity)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR025110|interpro:IPR030307|interpro:IPR042099|reactome:R-HSA-75876|refseq:NP_001304858.2|refseq:NP_077306.2|genbank_nucl_gi:13236579(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:eBOyI1TfCgExBrXLxSwlUZ05NXs9606	rogid:l707ITB0BdR+f+VaYhtbXUBsFqs9606	rigid:bJrxHziBBdGXYnqj1ugE9BOmjmE	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BSJ8	uniprotkb:Q5BJH7	intact:EBI-355956|ensembl:ENSP00000377612|uniprotkb:A0FGR7|uniprotkb:A8K2S2|uniprotkb:O94848|uniprotkb:Q6PJN4|uniprotkb:Q9H6J1|uniprotkb:Q9H6W2|uniprotkb:Q9Y416|intact:EBI-4399548	intact:EBI-11288011|uniprotkb:H7BXS8|uniprotkb:Q5JPC2|uniprotkb:Q8WY70|uniprotkb:Q96C02|uniprotkb:Q96IC4|ensembl:ENSP00000343435	psi-mi:esyt1_human(display_long)|uniprotkb:KIAA0747(gene name synonym)|uniprotkb:MBC2(gene name synonym)|uniprotkb:ESYT1(gene name)|psi-mi:ESYT1(display_short)|uniprotkb:Membrane-bound C2 domain-containing protein(gene name synonym)|uniprotkb:FAM62A(gene name synonym)	psi-mi:yif1b_human(display_long)|uniprotkb:YIF1B(gene name)|psi-mi:YIF1B(display_short)|uniprotkb:YIP1-interacting factor homolog B(gene name synonym)|uniprotkb:PP4519(orf name)|uniprotkb:UNQ3073/PRO9905(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25769953|imex:IM-28143-108	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR037752|interpro:IPR039010|mint:Q9BSJ8|reactome:R-HSA-1660662|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9035034|interpro:IPR037749|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037733|go:"GO:0005544"(calcium-dependent phospholipid binding)|ensembl:ENSG00000139641(gene)|ensembl:ENST00000394048(transcript)|go:"GO:0005509"(calcium ion binding)|refseq:NP_001171725.1|refseq:NP_056107.1|dip:DIP-57197N	refseq:NP_001034761.1|refseq:NP_001034762.1|refseq:NP_001138934.1|refseq:NP_001138935.1|refseq:XP_005259442.1|refseq:XP_016882938.1|ensembl:ENSG00000167645(gene)|ensembl:ENST00000339413(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR005578(Hrf1)|mint:Q5BJH7|genbank_nucl_gi:89191845(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:MYbYK3357LLH0TP1qU7CsvJenGk9606	rogid:Vq4GGKQqOKq1sydz+NMnUNcriWQ9606	rigid:SbFUWeUi+QjLoviL/Nx9Khx6s54	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BSJ8	uniprotkb:O75915	intact:EBI-355956|ensembl:ENSP00000377612|uniprotkb:A0FGR7|uniprotkb:A8K2S2|uniprotkb:O94848|uniprotkb:Q6PJN4|uniprotkb:Q9H6J1|uniprotkb:Q9H6W2|uniprotkb:Q9Y416|intact:EBI-4399548	intact:EBI-2860752|uniprotkb:B2R6V5|uniprotkb:Q53ES3|uniprotkb:Q5KU08|ensembl:ENSP00000273258	psi-mi:esyt1_human(display_long)|uniprotkb:KIAA0747(gene name synonym)|uniprotkb:MBC2(gene name synonym)|uniprotkb:ESYT1(gene name)|psi-mi:ESYT1(display_short)|uniprotkb:Membrane-bound C2 domain-containing protein(gene name synonym)|uniprotkb:FAM62A(gene name synonym)	psi-mi:praf3_human(display_long)|uniprotkb:ARL6IP5(gene name)|psi-mi:ARL6IP5(display_short)|uniprotkb:DERP11(gene name synonym)|uniprotkb:JWA(gene name synonym)|uniprotkb:PRA2(gene name synonym)|uniprotkb:PRAF3(gene name synonym)|uniprotkb:ADP-ribosylation factor-like protein 6-interacting protein 5(gene name synonym)|uniprotkb:Cytoskeleton-related vitamin A-responsive protein(gene name synonym)|uniprotkb:Dermal papilla-derived protein 11(gene name synonym)|uniprotkb:GTRAP3-18(gene name synonym)|uniprotkb:Glutamate transporter EAAC1-interacting protein(gene name synonym)|uniprotkb:JM5(gene name synonym)|uniprotkb:Prenylated Rab acceptor protein 2(gene name synonym)|uniprotkb:Protein JWa(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM27(gene name synonym)|uniprotkb:HSPC127(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25769953|imex:IM-28143-108	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR037752|interpro:IPR039010|mint:Q9BSJ8|reactome:R-HSA-1660662|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9035034|interpro:IPR037749|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037733|go:"GO:0005544"(calcium-dependent phospholipid binding)|ensembl:ENSG00000139641(gene)|ensembl:ENST00000394048(transcript)|go:"GO:0005509"(calcium ion binding)|refseq:NP_001171725.1|refseq:NP_056107.1|dip:DIP-57197N	refseq:NP_006398.1|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051051"(negative regulation of transport)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098712"(L-glutamate import across plasma membrane)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:O75915|reactome:R-HSA-210500|ensembl:ENSG00000144746(gene)|ensembl:ENST00000273258(transcript)|go:"GO:0002037"(negative regulation of L-glutamate import across plasma membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0007611"(learning or memory)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0015031"(protein transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036475"(neuron death in response to oxidative stress)|go:"GO:0043065"(positive regulation of apoptotic process)|genbank_nucl_gi:57012996(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:MYbYK3357LLH0TP1qU7CsvJenGk9606	rogid:TG2yH1gqzVhFgxBtuZqsE1dLAvQ9606	rigid:SbFUWeUi+QjLoviL/Nx9Khx6s54	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BSJ8	uniprotkb:A0FGR8	intact:EBI-355956|ensembl:ENSP00000377612|uniprotkb:A0FGR7|uniprotkb:A8K2S2|uniprotkb:O94848|uniprotkb:Q6PJN4|uniprotkb:Q9H6J1|uniprotkb:Q9H6W2|uniprotkb:Q9Y416|intact:EBI-4399548	intact:EBI-3184170|uniprotkb:Q9ULJ2|uniprotkb:Q9NW47|uniprotkb:Q69YJ2|uniprotkb:Q6ZVU1|uniprotkb:Q6UKI4|uniprotkb:Q6ZTU0|uniprotkb:Q9BQS0|uniprotkb:A4D229	psi-mi:esyt1_human(display_long)|uniprotkb:KIAA0747(gene name synonym)|uniprotkb:MBC2(gene name synonym)|uniprotkb:ESYT1(gene name)|psi-mi:ESYT1(display_short)|uniprotkb:Membrane-bound C2 domain-containing protein(gene name synonym)|uniprotkb:FAM62A(gene name synonym)	psi-mi:esyt2_human(display_long)|uniprotkb:ESYT2(gene name)|psi-mi:ESYT2(display_short)|uniprotkb:FAM62B(gene name synonym)|uniprotkb:KIAA1228(gene name synonym)|uniprotkb:Chr2Syt(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25769953|imex:IM-28143-108	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR037752|interpro:IPR039010|mint:Q9BSJ8|reactome:R-HSA-1660662|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9035034|interpro:IPR037749|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037733|go:"GO:0005544"(calcium-dependent phospholipid binding)|ensembl:ENSG00000139641(gene)|ensembl:ENST00000394048(transcript)|go:"GO:0005509"(calcium ion binding)|refseq:NP_001171725.1|refseq:NP_056107.1|dip:DIP-57197N	go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016020"(membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0045296"(cadherin binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0140268"(endoplasmic reticulum-plasma membrane contact site)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR031468|interpro:IPR035892|go:"GO:0005789"(endoplasmic reticulum membrane)|interpro:IPR037733|interpro:IPR037749|interpro:IPR037752|interpro:IPR039010|rcsb pdb:2DMG|rcsb pdb:4NPJ|rcsb pdb:4NPK|rcsb pdb:4P42|reactome:R-HSA-1660662|refseq:NP_065779.1|mint:A0FGR8|dip:DIP-61039N|genbank_nucl_gi:45387945(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:MYbYK3357LLH0TP1qU7CsvJenGk9606	rogid:mOkUWt8oia02xtJYM6gQz3tsav89606	rigid:SbFUWeUi+QjLoviL/Nx9Khx6s54	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BSJ8	uniprotkb:P57105	intact:EBI-355956|ensembl:ENSP00000377612|uniprotkb:A0FGR7|uniprotkb:A8K2S2|uniprotkb:O94848|uniprotkb:Q6PJN4|uniprotkb:Q9H6J1|uniprotkb:Q9H6W2|uniprotkb:Q9Y416|intact:EBI-4399548	intact:EBI-1049004|uniprotkb:Q96IA4|uniprotkb:Q49SH3|ensembl:ENSP00000256366	psi-mi:esyt1_human(display_long)|uniprotkb:KIAA0747(gene name synonym)|uniprotkb:MBC2(gene name synonym)|uniprotkb:ESYT1(gene name)|psi-mi:ESYT1(display_short)|uniprotkb:Membrane-bound C2 domain-containing protein(gene name synonym)|uniprotkb:FAM62A(gene name synonym)	psi-mi:syj2b_human(display_long)|uniprotkb:Mitochondrial outer membrane protein 25(gene name synonym)|uniprotkb:SYNJ2BP(gene name)|psi-mi:SYNJ2BP(display_short)|uniprotkb:OMP25(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25769953|imex:IM-28143-108	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR037752|interpro:IPR039010|mint:Q9BSJ8|reactome:R-HSA-1660662|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9035034|interpro:IPR037749|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037733|go:"GO:0005544"(calcium-dependent phospholipid binding)|ensembl:ENSG00000139641(gene)|ensembl:ENST00000394048(transcript)|go:"GO:0005509"(calcium ion binding)|refseq:NP_001171725.1|refseq:NP_056107.1|dip:DIP-57197N	refseq:NP_060843.2|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|rcsb pdb:2ENO|rcsb pdb:2JIK|rcsb pdb:2JIN|ensembl:ENSG00000213463(gene)|ensembl:ENST00000256366(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0005739"(mitochondrion)|go:"GO:0007268"(chemical synaptic transmission)|genbank_nucl_gi:22261816(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:MYbYK3357LLH0TP1qU7CsvJenGk9606	rogid:6U2Fgt1o1/WTmxeIfpcWYhik06U9606	rigid:SbFUWeUi+QjLoviL/Nx9Khx6s54	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O94905	uniprotkb:O75477	intact:EBI-4400770|uniprotkb:A0JLQ1|uniprotkb:A8K5S9|uniprotkb:B4DM38|uniprotkb:D3DSW0|uniprotkb:Q6NW21|uniprotkb:Q86VS6|uniprotkb:Q86W49|ensembl:ENSP00000428112	intact:EBI-359299|uniprotkb:B0QZ42|uniprotkb:Q53HV0|ensembl:ENSP00000384900|ensembl:ENSP00000410964|intact:EBI-21351077|uniprotkb:D3DR65	psi-mi:erln2_human(display_long)|uniprotkb:ERLIN2(gene name)|psi-mi:ERLIN2(display_short)|uniprotkb:C8orf2(gene name synonym)|uniprotkb:SPFH2(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 2(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2(gene name synonym)|uniprotkb:UNQ2441/PRO5003/PRO9924(orf name)	psi-mi:erln1_human(display_long)|uniprotkb:KEO4(gene name synonym)|uniprotkb:ERLIN1(gene name)|psi-mi:ERLIN1(display_short)|uniprotkb:C10orf69(gene name synonym)|uniprotkb:KE04(gene name synonym)|uniprotkb:SPFH1(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 1(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1(gene name synonym)|uniprotkb:Protein KE04(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770016|imex:IM-28143-50	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001003790.1|refseq:NP_001003791.1|refseq:NP_009106.1|refseq:XP_016868489.1|refseq:XP_005273449.1|ensembl:ENSG00000147475(gene)|ensembl:ENST00000519638(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045121"(membrane raft)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O94905|reactome:R-HSA-382556|reactome:R-HSA-5655302|reactome:R-HSA-5678895|reactome:R-HSA-8853336	refseq:NP_001094096.1|refseq:NP_006450.2|ensembl:ENSG00000107566(gene)|ensembl:ENST00000407654(transcript)|ensembl:ENST00000421367(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O75477|reactome:R-HSA-382556|reactome:R-HSA-5678895|refseq:NP_001334786.1|refseq:NP_001334788.1|refseq:NP_001334789.1|refseq:NP_001334790.1|genbank_nucl_gi:67461552(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:Evjg3G0FFeQ499BNlJxpK6t8to89606	rogid:HycFhL5qL5GLmaIIc9NtTcBbu1M9606	rigid:wAra7psykOOHrzT1DZHueaW1OYU	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O94905	uniprotkb:Q6LC01	intact:EBI-4400770|uniprotkb:A0JLQ1|uniprotkb:A8K5S9|uniprotkb:B4DM38|uniprotkb:D3DSW0|uniprotkb:Q6NW21|uniprotkb:Q86VS6|uniprotkb:Q86W49|ensembl:ENSP00000428112	intact:EBI-9201722	psi-mi:erln2_human(display_long)|uniprotkb:ERLIN2(gene name)|psi-mi:ERLIN2(display_short)|uniprotkb:C8orf2(gene name synonym)|uniprotkb:SPFH2(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 2(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2(gene name synonym)|uniprotkb:UNQ2441/PRO5003/PRO9924(orf name)	psi-mi:q6lc01_human(display_long)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770016|imex:IM-28143-50	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001003790.1|refseq:NP_001003791.1|refseq:NP_009106.1|refseq:XP_016868489.1|refseq:XP_005273449.1|ensembl:ENSG00000147475(gene)|ensembl:ENST00000519638(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045121"(membrane raft)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O94905|reactome:R-HSA-382556|reactome:R-HSA-5655302|reactome:R-HSA-5678895|reactome:R-HSA-8853336	interpro:IPR002453(Beta tubulin)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR000217(Tubulin)|interpro:IPR018316|interpro:IPR017975|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR023123|go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|interpro:IPR036525|interpro:IPR037103|genbank_nucl_gi:2119276(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:Evjg3G0FFeQ499BNlJxpK6t8to89606	rogid:/WGeYWB5j/CRWcvsU2CL4CdOLcY9606	rigid:wAra7psykOOHrzT1DZHueaW1OYU	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O94905	uniprotkb:P51452	intact:EBI-4400770|uniprotkb:A0JLQ1|uniprotkb:A8K5S9|uniprotkb:B4DM38|uniprotkb:D3DSW0|uniprotkb:Q6NW21|uniprotkb:Q86VS6|uniprotkb:Q86W49|ensembl:ENSP00000428112	intact:EBI-1049755|uniprotkb:Q5U0J1|uniprotkb:D3DX45|ensembl:ENSP00000226004|uniprotkb:Q8IYJ9	psi-mi:erln2_human(display_long)|uniprotkb:ERLIN2(gene name)|psi-mi:ERLIN2(display_short)|uniprotkb:C8orf2(gene name synonym)|uniprotkb:SPFH2(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 2(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2(gene name synonym)|uniprotkb:UNQ2441/PRO5003/PRO9924(orf name)	psi-mi:dus3_human(display_long)|uniprotkb:Dual specificity protein phosphatase VHR(gene name synonym)|uniprotkb:DUSP3(gene name)|psi-mi:DUSP3(display_short)|uniprotkb:VHR(gene name synonym)|uniprotkb:Vaccinia H1-related phosphatase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770016|imex:IM-28143-50	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001003790.1|refseq:NP_001003791.1|refseq:NP_009106.1|refseq:XP_016868489.1|refseq:XP_005273449.1|ensembl:ENSG00000147475(gene)|ensembl:ENST00000519638(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045121"(membrane raft)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O94905|reactome:R-HSA-382556|reactome:R-HSA-5655302|reactome:R-HSA-5678895|reactome:R-HSA-8853336	refseq:NP_004081.1|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0001772"(immunological synapse)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033549"(MAP kinase phosphatase activity)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050868"(negative regulation of T cell activation)|go:"GO:0050922"(negative regulation of chemotaxis)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1990264"(peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020405|interpro:IPR020422|interpro:IPR029021|rcsb pdb:1J4X|rcsb pdb:1VHR|rcsb pdb:3F81|reactome:R-HSA-202670|ensembl:ENSG00000108861(gene)|ensembl:ENST00000226004(transcript)|genbank_nucl_gi:1718191(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:Evjg3G0FFeQ499BNlJxpK6t8to89606	rogid:1kqI9JZrOBsMIH4M2AoWBOmQPko9606	rigid:wAra7psykOOHrzT1DZHueaW1OYU	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O94905	uniprotkb:Q4ZIN3	intact:EBI-4400770|uniprotkb:A0JLQ1|uniprotkb:A8K5S9|uniprotkb:B4DM38|uniprotkb:D3DSW0|uniprotkb:Q6NW21|uniprotkb:Q86VS6|uniprotkb:Q86W49|ensembl:ENSP00000428112	intact:EBI-718159|uniprotkb:O60392|uniprotkb:Q8NF79|uniprotkb:Q96H30|ensembl:ENSP00000349087	psi-mi:erln2_human(display_long)|uniprotkb:ERLIN2(gene name)|psi-mi:ERLIN2(display_short)|uniprotkb:C8orf2(gene name synonym)|uniprotkb:SPFH2(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 2(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2(gene name synonym)|uniprotkb:UNQ2441/PRO5003/PRO9924(orf name)	psi-mi:mbrl_human(display_long)|uniprotkb:TMEM259(gene name)|psi-mi:TMEM259(display_short)|uniprotkb:C19orf6(gene name synonym)|uniprotkb:Transmembrane protein 259(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770016|imex:IM-28143-50	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001003790.1|refseq:NP_001003791.1|refseq:NP_009106.1|refseq:XP_016868489.1|refseq:XP_005273449.1|ensembl:ENSG00000147475(gene)|ensembl:ENST00000519638(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045121"(membrane raft)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O94905|reactome:R-HSA-382556|reactome:R-HSA-5655302|reactome:R-HSA-5678895|reactome:R-HSA-8853336	refseq:NP_001028198.1|refseq:NP_219488.1|ensembl:ENSG00000182087(gene)|ensembl:ENST00000356663(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1904294"(positive regulation of ERAD pathway)|interpro:IPR019144|mint:Q4ZIN3|genbank_nucl_gi:15529970(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:Evjg3G0FFeQ499BNlJxpK6t8to89606	rogid:9pOT/zZF8drU1qnANZaZaMgVmUo9606	rigid:wAra7psykOOHrzT1DZHueaW1OYU	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O94905	uniprotkb:P52272	intact:EBI-4400770|uniprotkb:A0JLQ1|uniprotkb:A8K5S9|uniprotkb:B4DM38|uniprotkb:D3DSW0|uniprotkb:Q6NW21|uniprotkb:Q86VS6|uniprotkb:Q86W49|ensembl:ENSP00000428112	intact:EBI-486809|uniprotkb:Q9Y492|uniprotkb:Q15584|uniprotkb:Q8WZ44|uniprotkb:Q96H56|uniprotkb:Q9BWL9|intact:EBI-28985795|ensembl:ENSP00000325376	psi-mi:erln2_human(display_long)|uniprotkb:ERLIN2(gene name)|psi-mi:ERLIN2(display_short)|uniprotkb:C8orf2(gene name synonym)|uniprotkb:SPFH2(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 2(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2(gene name synonym)|uniprotkb:UNQ2441/PRO5003/PRO9924(orf name)	psi-mi:hnrpm_human(display_long)|uniprotkb:HNRNPM(gene name)|psi-mi:HNRNPM(display_short)|uniprotkb:HNRPM(gene name synonym)|uniprotkb:NAGR1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770016|imex:IM-28143-50	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001003790.1|refseq:NP_001003791.1|refseq:NP_009106.1|refseq:XP_016868489.1|refseq:XP_005273449.1|ensembl:ENSG00000147475(gene)|ensembl:ENST00000519638(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045121"(membrane raft)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O94905|reactome:R-HSA-382556|reactome:R-HSA-5655302|reactome:R-HSA-5678895|reactome:R-HSA-8853336	refseq:NP_005959.2|refseq:NP_112480.2|ensembl:ENSG00000099783(gene)|ensembl:ENST00000325495(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042382"(paraspeckles)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000815"(regulation of mRNA stability involved in response to oxidative stress)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR024666|interpro:IPR024667|interpro:IPR034990|interpro:IPR035979|mint:P52272|rcsb pdb:2DGV|rcsb pdb:2DH9|rcsb pdb:2DO0|rcsb pdb:2OT8|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|dip:DIP-29336N|ensembl:ENSP00000325376|ensembl:ENST00000348943|ensembl:ENSP00000325732|genbank_nucl_gi:14141152(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:Evjg3G0FFeQ499BNlJxpK6t8to89606	rogid:5FnCgrz0xltEkgw3yh70KP2jz5g9606	rigid:wAra7psykOOHrzT1DZHueaW1OYU	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q14139	uniprotkb:Q92575	intact:EBI-1048119|uniprotkb:Q2M1H0|uniprotkb:Q6P5T4|uniprotkb:Q7Z639|uniprotkb:B0YJB6|ensembl:ENSP00000252108	intact:EBI-723441|uniprotkb:Q4ZG56|uniprotkb:Q8IYM5|intact:EBI-28978946|ensembl:ENSP00000272638|uniprotkb:A8K9W4	psi-mi:ube4a_human(display_long)|uniprotkb:UBE4A(gene name)|psi-mi:UBE4A(display_short)|uniprotkb:KIAA0126(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase E4 A(gene name synonym)	psi-mi:ubxn4_human(display_long)|uniprotkb:Erasin(gene name synonym)|uniprotkb:UBXN4(gene name)|psi-mi:UBXN4(display_short)|uniprotkb:KIAA0242(gene name synonym)|uniprotkb:UBXDC1(gene name synonym)|uniprotkb:UBXD2(gene name synonym)|uniprotkb:UBX domain-containing protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770130|imex:IM-28143-34	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191006.1|refseq:NP_004779.2|ensembl:ENSG00000110344(gene)|ensembl:ENST00000252108(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019474|rcsb pdb:1WGM|reactome:R-HSA-983168|genbank_nucl_gi:71164791(identity)	refseq:NP_055422.1|ensembl:ENSG00000144224(gene)|ensembl:ENST00000272638(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|interpro:IPR001012(UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:2KXJ|ensembl:ENSP00000272638	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:nk+uYWQ8ytS/qOjUkCDf9dAymPU9606	rogid:rWCmtHlje9EFw7YVQQNJBBH4bLE9606	rigid:ilKVqM9Mh4zSJRTVLN6XEinxPiQ	false	-	s tag:?-?	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86TM6	uniprotkb:Q9UBU6	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	intact:EBI-6309101|intact:EBI-28967558|ensembl:ENSP00000259963|uniprotkb:B2R725	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:fa8a1_human(display_long)|uniprotkb:FAM8A1(gene name)|psi-mi:FAM8A1(display_short)|uniprotkb:AHCP(gene name synonym)|uniprotkb:Autosomal highly conserved protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770037|imex:IM-28143-32	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	ensembl:ENSP00000259963|ensembl:ENSG00000137414(gene)|ensembl:ENST00000259963(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|interpro:IPR010432(RDD)|interpro:IPR039871|refseq:NP_057339.1|genbank_nucl_gi:74753230(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rogid:0HV6qye10bMGdnt9CiGztIacrHM9606	rigid:BI3tXBFYZrWhhIbT3YucC7rdeIA	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86TM6	uniprotkb:Q96DZ1	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	intact:EBI-1023677|uniprotkb:O95901|uniprotkb:Q6UWN7|uniprotkb:Q9NUY7|uniprotkb:Q9UQL4|uniprotkb:B2RDB4|ensembl:ENSP00000185150|uniprotkb:B5MC72	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:erlec_human(display_long)|uniprotkb:ER lectin(gene name synonym)|uniprotkb:ERLEC1(gene name)|psi-mi:ERLEC1(display_short)|uniprotkb:XTP3TPB(gene name synonym)|uniprotkb:UNQ1878/PRO4321(orf name)|uniprotkb:C2orf30(gene name synonym)|uniprotkb:XTP3-transactivated gene B protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770037|imex:IM-28143-32	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	refseq:NP_001120870.1|refseq:NP_056516.2|ensembl:ENSG00000068912(gene)|ensembl:ENST00000185150(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR044865|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|refseq:NP_001120869.1|genbank_nucl_gi:74731510(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rogid:eBOyI1TfCgExBrXLxSwlUZ05NXs9606	rigid:BI3tXBFYZrWhhIbT3YucC7rdeIA	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86TM6	uniprotkb:O75477	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	intact:EBI-359299|uniprotkb:B0QZ42|uniprotkb:Q53HV0|ensembl:ENSP00000384900|ensembl:ENSP00000410964|intact:EBI-21351077|uniprotkb:D3DR65	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:erln1_human(display_long)|uniprotkb:KEO4(gene name synonym)|uniprotkb:ERLIN1(gene name)|psi-mi:ERLIN1(display_short)|uniprotkb:C10orf69(gene name synonym)|uniprotkb:KE04(gene name synonym)|uniprotkb:SPFH1(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 1(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1(gene name synonym)|uniprotkb:Protein KE04(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770037|imex:IM-28143-32	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	refseq:NP_001094096.1|refseq:NP_006450.2|ensembl:ENSG00000107566(gene)|ensembl:ENST00000407654(transcript)|ensembl:ENST00000421367(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O75477|reactome:R-HSA-382556|reactome:R-HSA-5678895|refseq:NP_001334786.1|refseq:NP_001334788.1|refseq:NP_001334789.1|refseq:NP_001334790.1|genbank_nucl_gi:67461552(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rogid:HycFhL5qL5GLmaIIc9NtTcBbu1M9606	rigid:BI3tXBFYZrWhhIbT3YucC7rdeIA	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86TM6	uniprotkb:Q9UBV2	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	intact:EBI-358766|uniprotkb:Q6UWT6|uniprotkb:Q9P1T9|uniprotkb:Q9UHK7|ensembl:ENSP00000337053	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:se1l1_human(display_long)|uniprotkb:SEL1L(gene name)|psi-mi:SEL1L(display_short)|uniprotkb:TSA305(gene name synonym)|uniprotkb:UNQ128/PRO1063(orf name)|uniprotkb:Suppressor of lin-12-like protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770037|imex:IM-28143-32	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	refseq:NP_001231913.1|refseq:NP_005056.3|ensembl:ENSG00000071537(gene)|ensembl:ENST00000336735(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0050821"(protein stabilization)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|mint:Q9UBV2|reactome:R-HSA-1912420|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-46259N|genbank_nucl_gi:62512184(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rogid:eufE+8nfcHK8CDl+AQ5G+3NtL+09606	rigid:BI3tXBFYZrWhhIbT3YucC7rdeIA	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86TM6	uniprotkb:P35579	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	intact:EBI-350338|uniprotkb:O60805|ensembl:ENSP00000216181|uniprotkb:Q86T83|intact:EBI-1054343|uniprotkb:A8K6E4|uniprotkb:Q60FE2	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:myh9_human(display_long)|uniprotkb:MYH9(gene name)|psi-mi:MYH9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770037|imex:IM-28143-32	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	refseq:NP_002464.1|ensembl:ENSG00000100345(gene)|ensembl:ENST00000216181(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001931"(uropod)|go:"GO:0003723"(RNA binding)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|refseq:XP_011528499.1|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030220"(platelet formation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032418"(lysosome localization)|go:"GO:0032506"(cytokinetic process)|go:"GO:0032796"(uropod organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045296"(cadherin binding)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051015"(actin filament binding)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0097513"(myosin II filament)|go:"GO:1903919"(negative regulation of actin filament severing)|rcsb pdb:4CFR|rcsb pdb:4ETO|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9662834|reactome:R-HSA-9664422|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1905684"(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036305|interpro:IPR036961|mint:P35579|rcsb pdb:2LNK|rcsb pdb:3ZWH|rcsb pdb:4CFQ|refseq:XP_016884292.1|refseq:XP_016884293.1|refseq:XP_016884294.1|refseq:XP_016884295.1|dip:DIP-33103N|genbank_nucl_gi:6166599(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rogid:fSOtpFpr8PSnAG5UdAr/khwkzJs9606	rigid:BI3tXBFYZrWhhIbT3YucC7rdeIA	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86TM6	uniprotkb:P37268	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	intact:EBI-714550|intact:EBI-1058542|uniprotkb:Q96GT0|ensembl:ENSP00000220584|ensembl:ENSP00000480828|ensembl:ENSP00000481481|uniprotkb:B3KQ95|uniprotkb:B4DJE5|uniprotkb:B4DT56|uniprotkb:B7Z1J3	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:fdft_human(display_long)|uniprotkb:Farnesyl-diphosphate farnesyltransferase(gene name synonym)|uniprotkb:"FPP:FPP farnesyltransferase"(gene name synonym)|uniprotkb:FDFT1(gene name)|psi-mi:FDFT1(display_short)|uniprotkb:Farnesyl-diphosphate farnesyltransferase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770037|imex:IM-28143-32	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	ensembl:ENST00000618539(transcript)|refseq:NP_004453.3|ensembl:ENSG00000079459(gene)|ensembl:ENST00000220584(transcript)|ensembl:ENST00000615631(transcript)|rcsb pdb:3LEE|rcsb pdb:3Q2Z|rcsb pdb:3Q30|rcsb pdb:3V66|rcsb pdb:3VJ8|rcsb pdb:3VJ9|rcsb pdb:3VJA|rcsb pdb:3VJB|rcsb pdb:3VJC|rcsb pdb:3WC9|rcsb pdb:3WCD|rcsb pdb:3WCF|rcsb pdb:3WCH|rcsb pdb:3WCI|rcsb pdb:3WCJ|rcsb pdb:3WCL|rcsb pdb:3WCM|rcsb pdb:3WEF|rcsb pdb:3WEG|rcsb pdb:3WEH|rcsb pdb:3WEI|rcsb pdb:3WEJ|rcsb pdb:3WEK|rcsb pdb:3WSA|rcsb pdb:6PYJ|rcsb pdb:6PYV|rcsb pdb:6PYW|rcsb pdb:6PZ5|reactome:R-HSA-191273|reactome:R-HSA-1989781|reactome:R-HSA-2426168|rcsb pdb:3ASX|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0004310"(farnesyl-diphosphate farnesyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045338"(farnesyl diphosphate metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051996"(squalene synthase activity)|interpro:IPR002060(Squalene/phytoene synthase)|interpro:IPR006449(Farnesyl-diphosphate farnesyltransferase)|interpro:IPR008949(Terpenoid synthase)|interpro:IPR019845|interpro:IPR033904|interpro:IPR044844|mint:P37268|rcsb pdb:1EZF|refseq:NP_001274671.1|refseq:NP_001274672.1|refseq:NP_001274673.1|refseq:NP_001274674.1|refseq:NP_001274676.1|refseq:NP_001274677.1|refseq:NP_001274678.1|refseq:NP_001274679.1|refseq:NP_001274680.1|refseq:NP_001274685.1|refseq:XP_016868706.1|genbank_nucl_gi:585126(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rogid:3TjanjXw3X58/ZOEsB1xczV0/qQ9606	rigid:BI3tXBFYZrWhhIbT3YucC7rdeIA	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86TM6	uniprotkb:Q9Y385	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	intact:EBI-988826|uniprotkb:Q5W0N4|uniprotkb:Q9BZ32|uniprotkb:Q9NQL3|uniprotkb:Q9NY66|uniprotkb:Q9P011|uniprotkb:Q9P0S0|uniprotkb:Q9UF10|ensembl:ENSP00000451261|uniprotkb:A8K3F9|uniprotkb:Q53F25	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:ub2j1_human(display_long)|uniprotkb:Non-canonical ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:Yeast ubiquitin-conjugating enzyme UBC6 homolog E(gene name synonym)|uniprotkb:UBE2J1(gene name)|psi-mi:UBE2J1(display_short)|uniprotkb:NCUBE1(gene name synonym)|uniprotkb:CGI-76(orf name)|uniprotkb:HSPC153(orf name)|uniprotkb:HSPC205(orf name)|uniprotkb:E2 ubiquitin-conjugating enzyme J1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770037|imex:IM-28143-32	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|reactome:R-HSA-983168|ensembl:ENSG00000198833(gene)|ensembl:ENST00000435041(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007286"(spermatid development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:NP_057105.2|dip:DIP-45598N|genbank_nucl_gi:52000881(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rogid:nc3+V3Qxy1ZDhTWgTPLakJukxPM9606	rigid:BI3tXBFYZrWhhIbT3YucC7rdeIA	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86TM6	uniprotkb:Q99460	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	intact:EBI-357874|uniprotkb:Q24JU0|uniprotkb:Q53TI2|uniprotkb:Q6GMU5|uniprotkb:Q6P2P4|uniprotkb:Q6PJM7|uniprotkb:Q6PKG9|uniprotkb:B8ZZH9|uniprotkb:Q86VU1|uniprotkb:Q8IV79|ensembl:ENSP00000309474|ensembl:ENSP00000503068	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:psmd1_human(display_long)|uniprotkb:PSMD1(gene name)|psi-mi:PSMD1(display_short)|uniprotkb:26S proteasome regulatory subunit RPN2(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S1(gene name synonym)|uniprotkb:26S proteasome subunit p112(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770037|imex:IM-28143-32	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	refseq:NP_001177966.1|refseq:NP_002798.2|dip:DIP-27548N|ensembl:ENSG00000173692(gene)|ensembl:ENST00000308696(transcript)|ensembl:ENST00000677230(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016642(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit)|interpro:IPR035266|interpro:IPR040623|mint:Q99460|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5V1Y|rcsb pdb:5V1Z|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6CO4|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6OI4|rcsb pdb:6UYI|rcsb pdb:6UYJ|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-382556|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|genbank_nucl_gi:51704332(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rogid:aGYxoT30PhzvF/CiurQLDb8Ewrs9606	rigid:BI3tXBFYZrWhhIbT3YucC7rdeIA	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86TM6	uniprotkb:P60900	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	intact:EBI-357793|uniprotkb:P34062|uniprotkb:Q6IB60|uniprotkb:B2R7J9|uniprotkb:B4DQR4|uniprotkb:B4DXJ9|ensembl:ENSP00000261479	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:psa6_human(display_long)|uniprotkb:PSMA6(gene name)|psi-mi:PSMA6(display_short)|uniprotkb:PROS27(gene name synonym)|uniprotkb:Proteasome iota chain(gene name synonym)|uniprotkb:Macropain iota chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex iota chain(gene name synonym)|uniprotkb:27 kDa prosomal protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770037|imex:IM-28143-32	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	refseq:NP_002782.1|refseq:NP_001269162.1|refseq:NP_001269163.1|refseq:XP_016876957.1|refseq:NP_001269161.1|ensembl:ENSG00000100902(gene)|ensembl:ENST00000261479(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0035639"(purine ribonucleoside triphosphate binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034642|mint:P60900|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-29367N|genbank_nucl_gi:46397659(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rogid:F+Kwr6rnDS3jD53gBGHDIn7HV/89606	rigid:BI3tXBFYZrWhhIbT3YucC7rdeIA	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86TM6	uniprotkb:P28066	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	intact:EBI-355475|uniprotkb:B4E2V4|uniprotkb:Q6IBF7|uniprotkb:Q3T1C1|uniprotkb:B2R8F6|ensembl:ENSP00000271308	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:psa5_human(display_long)|uniprotkb:PSMA5(gene name)|psi-mi:PSMA5(display_short)|uniprotkb:Proteasome zeta chain(gene name synonym)|uniprotkb:Macropain zeta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex zeta chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770037|imex:IM-28143-32	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	refseq:NP_001186701.1|refseq:NP_001186702.1|refseq:NP_001186703.1|refseq:NP_002781.2|ensembl:ENSG00000143106(gene)|ensembl:ENST00000271308(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR033812|mint:P28066|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEY|rcsb pdb:5LEX|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-29368N|genbank_nucl_gi:38258905(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rogid:bfMG3npzVetUH1tahr2MAI4R+3g9606	rigid:BI3tXBFYZrWhhIbT3YucC7rdeIA	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86TM6	uniprotkb:O94905	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	intact:EBI-4400770|uniprotkb:A0JLQ1|uniprotkb:A8K5S9|uniprotkb:B4DM38|uniprotkb:D3DSW0|uniprotkb:Q6NW21|uniprotkb:Q86VS6|uniprotkb:Q86W49|ensembl:ENSP00000428112	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:erln2_human(display_long)|uniprotkb:ERLIN2(gene name)|psi-mi:ERLIN2(display_short)|uniprotkb:C8orf2(gene name synonym)|uniprotkb:SPFH2(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 2(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2(gene name synonym)|uniprotkb:UNQ2441/PRO5003/PRO9924(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770037|imex:IM-28143-32	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	refseq:NP_001003790.1|refseq:NP_001003791.1|refseq:NP_009106.1|refseq:XP_016868489.1|refseq:XP_005273449.1|ensembl:ENSG00000147475(gene)|ensembl:ENST00000519638(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045121"(membrane raft)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O94905|reactome:R-HSA-382556|reactome:R-HSA-5655302|reactome:R-HSA-5678895|reactome:R-HSA-8853336|genbank_nucl_gi:38257366(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rogid:Evjg3G0FFeQ499BNlJxpK6t8to89606	rigid:BI3tXBFYZrWhhIbT3YucC7rdeIA	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86TM6	uniprotkb:Q13438	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	intact:EBI-725454|intact:EBI-1174342|uniprotkb:A6NDD1|uniprotkb:A6NFR7|uniprotkb:A6NLB2|uniprotkb:A8K5Q9|uniprotkb:B4DPX1|uniprotkb:B4E1I6|uniprotkb:E7ENT8|uniprotkb:F8VUH2|uniprotkb:O00579|uniprotkb:Q6IBL2|uniprotkb:Q8IZ58|uniprotkb:Q9BW99|uniprotkb:B4DE28|ensembl:ENSP00000318165|uniprotkb:E7EW91|uniprotkb:G3XA88	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:os9_human(display_long)|uniprotkb:OS9(gene name)|psi-mi:OS9(display_short)|uniprotkb:Amplified in osteosarcoma 9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770037|imex:IM-28143-32	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	refseq:NP_006803.1|refseq:NP_001017956.1|refseq:NP_001017957.1|refseq:NP_001017958.1|refseq:NP_001248349.1|refseq:NP_001248350.1|refseq:NP_001248351.1|refseq:NP_001248352.1|ensembl:ENSG00000135506(gene)|ensembl:ENST00000315970(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0002020"(protease binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006605"(protein targeting)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|interpro:IPR044865|rcsb pdb:3AIH|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-37493N|genbank_nucl_gi:3024310(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rogid:Ntc3geE7th+rBeIp0MxuUuu/28Y9606	rigid:BI3tXBFYZrWhhIbT3YucC7rdeIA	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86TM6	uniprotkb:P16435	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	intact:EBI-726554|uniprotkb:Q9UDT3|uniprotkb:Q16455|uniprotkb:Q8N181|uniprotkb:Q9H3M8|uniprotkb:Q197M5|ensembl:ENSP00000378355|ensembl:ENSP00000389409|ensembl:ENSP00000389719|ensembl:ENSP00000390540|ensembl:ENSP00000395813|ensembl:ENSP00000399327|ensembl:ENSP00000399556|ensembl:ENSP00000404731|ensembl:ENSP00000409238|ensembl:ENSP00000414263|ensembl:ENSP00000419970	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:ncpr_human(display_long)|uniprotkb:POR(gene name)|psi-mi:POR(display_short)|uniprotkb:CYPOR(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770037|imex:IM-28143-32	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	refseq:NP_000932.3|ensembl:ENSG00000127948(gene)|ensembl:ENST00000394893(transcript)|ensembl:ENST00000412064(transcript)|ensembl:ENST00000412521(transcript)|ensembl:ENST00000414186(transcript)|ensembl:ENST00000418341(transcript)|ensembl:ENST00000432753(transcript)|ensembl:ENST00000439963(transcript)|ensembl:ENST00000449920(transcript)|ensembl:ENST00000453773(transcript)|ensembl:ENST00000454934(transcript)|ensembl:ENST00000461988(transcript)|go:"GO:0003420"(regulation of growth plate cartilage chondrocyte proliferation)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008941"(nitric oxide dioxygenase activity)|go:"GO:0009055"(electron transfer activity)|go:"GO:0009437"(carnitine metabolic process)|go:"GO:0009725"(response to hormone)|go:"GO:0009812"(flavonoid metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0016787"(hydrolase activity)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0019899"(enzyme binding)|go:"GO:0022900"(electron transport chain)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032770"(positive regulation of monooxygenase activity)|go:"GO:0042493"|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043602"(nitrate catabolic process)|go:"GO:0045542"(positive regulation of cholesterol biosynthetic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046210"(nitric oxide catabolic process)|go:"GO:0047726"(iron-cytochrome-c reductase activity)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:0060192"(negative regulation of lipase activity)|go:"GO:0070988"(demethylation)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090031"(positive regulation of steroid hormone biosynthetic process)|go:"GO:0090346"(cellular organofluorine metabolic process)|interpro:IPR001094(Flavodoxin-like)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023173|interpro:IPR023208|interpro:IPR029039|interpro:IPR039261|rcsb pdb:1B1C|rcsb pdb:3FJO|rcsb pdb:3QE2|rcsb pdb:3QFC|rcsb pdb:3QFR|rcsb pdb:3QFS|rcsb pdb:3QFT|rcsb pdb:5EMN|rcsb pdb:5FA6|reactome:R-HSA-211897|dip:DIP-29682N|genbank_nucl_gi:2851393(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rogid:Tgl0hfwgwo16Yw+kH4JIdIaRPpM9606	rigid:BI3tXBFYZrWhhIbT3YucC7rdeIA	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86TM6	uniprotkb:P51665	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	intact:EBI-357659|uniprotkb:Q6PKI2|uniprotkb:Q96E97|ensembl:ENSP00000219313|uniprotkb:D3DWS9	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:psmd7_human(display_long)|uniprotkb:PSMD7(gene name)|psi-mi:PSMD7(display_short)|uniprotkb:MOV34L(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN8(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S12(gene name synonym)|uniprotkb:Proteasome subunit p40(gene name synonym)|uniprotkb:Mov34 protein homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770037|imex:IM-28143-32	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	refseq:NP_002802.2|rcsb pdb:5T0J|ensembl:ENSG00000103035(gene)|ensembl:ENST00000219313(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0016020"(membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070122"(isopeptidase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR033858|interpro:IPR037518|mint:P51665|rcsb pdb:2O95|rcsb pdb:2O96|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-180534|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-195253|reactome:R-HSA-5676590|reactome:R-HSA-202424|reactome:R-HSA-5678895|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-2871837|reactome:R-HSA-5689880|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-6798695|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-68827|reactome:R-HSA-4641258|reactome:R-HSA-68949|reactome:R-HSA-5358346|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-27572N|genbank_nucl_gi:20532412(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rogid:HJaBTx4pIiSDIArqueuNRvhzVvU9606	rigid:BI3tXBFYZrWhhIbT3YucC7rdeIA	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86TM6	uniprotkb:P49720	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	intact:EBI-603340|uniprotkb:P31147|uniprotkb:Q0P6J7|uniprotkb:Q96E27|ensembl:ENSP00000483688|ensembl:ENSP00000483956	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:psb3_human(display_long)|uniprotkb:PSMB3(gene name)|psi-mi:PSMB3(display_short)|uniprotkb:Proteasome theta chain(gene name synonym)|uniprotkb:Proteasome chain 13(gene name synonym)|uniprotkb:Proteasome component C10-II(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770037|imex:IM-28143-32	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	refseq:NP_002786.2|dip:DIP-33846N|ensembl:ENSG00000275903(gene)|ensembl:ENSG00000277791(gene)|ensembl:ENST00000619426(transcript)|ensembl:ENST00000619951(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR033811|mint:P49720|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|genbank_nucl_gi:20532411(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rogid:H4UDdXV1BaXHp6mEPafNy+Iv8389606	rigid:BI3tXBFYZrWhhIbT3YucC7rdeIA	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86TM6	uniprotkb:P28072	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	intact:EBI-359288|uniprotkb:Q96J55|ensembl:ENSP00000270586	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:psb6_human(display_long)|uniprotkb:PSMB6(gene name)|psi-mi:PSMB6(display_short)|uniprotkb:LMPY(gene name synonym)|uniprotkb:Proteasome delta chain(gene name synonym)|uniprotkb:Macropain delta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex delta chain(gene name synonym)|uniprotkb:Proteasome subunit Y(gene name synonym)|uniprotkb:Y(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770037|imex:IM-28143-32	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	refseq:NP_002789.1|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035140|mint:P28072|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|go:"GO:0005737"(cytoplasm)|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000142507(gene)|ensembl:ENST00000270586(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-33847N|genbank_nucl_gi:20532407(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rogid:4LRxYA6/tM2hsc96iP29c5J7ew49606	rigid:BI3tXBFYZrWhhIbT3YucC7rdeIA	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86TM6	uniprotkb:P28074	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	intact:EBI-357828|uniprotkb:Q16242|uniprotkb:Q6PEW2|intact:EBI-1237472|uniprotkb:Q7Z3B5|uniprotkb:Q9TNN9|uniprotkb:B2R4N9|uniprotkb:D3DS43|uniprotkb:B4DUM9|uniprotkb:Q86T01|uniprotkb:E9PAV2|ensembl:ENSP00000355325	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:psb5_human(display_long)|uniprotkb:PSMB5(gene name)|psi-mi:PSMB5(display_short)|uniprotkb:LMPX(gene name synonym)|uniprotkb:Proteasome epsilon chain(gene name synonym)|uniprotkb:Macropain epsilon chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex epsilon chain(gene name synonym)|uniprotkb:Proteasome subunit X(gene name synonym)|uniprotkb:Proteasome chain 6(gene name synonym)|uniprotkb:Proteasome subunit MB1(gene name synonym)|uniprotkb:MB1(gene name synonym)|uniprotkb:X(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770037|imex:IM-28143-32	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	refseq:NP_001124197.1|refseq:NP_001138404.1|refseq:NP_002788.1|dip:DIP-27540N|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5610785|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|ensembl:ENSG00000100804(gene)|ensembl:ENST00000361611(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006508"(proteolysis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008233"(peptidase activity)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|mint:P28074|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|genbank_nucl_gi:187608890(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rogid:73T59wniLri/465F3BhBvwL1/LM9606	rigid:BI3tXBFYZrWhhIbT3YucC7rdeIA	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86TM6	uniprotkb:Q99436	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	intact:EBI-603319|uniprotkb:Q96AG8|uniprotkb:Q9BWA7|uniprotkb:B4E0P1|uniprotkb:Q5TBG6|ensembl:ENSP00000259457	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:psb7_human(display_long)|uniprotkb:PSMB7(gene name)|psi-mi:PSMB7(display_short)|uniprotkb:Proteasome subunit Z(gene name synonym)|uniprotkb:Macropain chain Z(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain Z(gene name synonym)|uniprotkb:Z(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770037|imex:IM-28143-32	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	refseq:NP_002790.1|dip:DIP-33843N|ensembl:ENSG00000136930(gene)|ensembl:ENST00000259457(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016604"(nuclear body)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR024689|interpro:IPR029055|interpro:IPR035216|mint:Q99436|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|genbank_nucl_gi:17380263(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rogid:w880QftOor3RdaGvhCup7apz2OM9606	rigid:BI3tXBFYZrWhhIbT3YucC7rdeIA	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86TM6	uniprotkb:Q68CR1	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	intact:EBI-723407|uniprotkb:A8K0X2|uniprotkb:Q6P999|uniprotkb:Q96G59|uniprotkb:O94847|uniprotkb:A0PJH6|ensembl:ENSP00000382767	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:se1l3_human(display_long)|uniprotkb:SEL1L3(gene name)|psi-mi:SEL1L3(display_short)|uniprotkb:KIAA0746(gene name synonym)|uniprotkb:Suppressor of lin-12-like protein 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770037|imex:IM-28143-32	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	refseq:NP_056002.2|refseq:NP_001284521.1|refseq:NP_001284523.1|ensembl:ENSG00000091490(gene)|ensembl:ENST00000399878(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016021"(integral component of membrane)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR042756|genbank_nucl_gi:172045726(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rogid:oxd3oWhlnQibMQDnrX6maCIYC509606	rigid:BI3tXBFYZrWhhIbT3YucC7rdeIA	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86TM6	uniprotkb:P49721	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	intact:EBI-359335|uniprotkb:P31145|uniprotkb:Q9BWZ9|uniprotkb:D3DPS0|ensembl:ENSP00000362334	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:psb2_human(display_long)|uniprotkb:PSMB2(gene name)|psi-mi:PSMB2(display_short)|uniprotkb:Multicatalytic endopeptidase complex subunit C7-I(gene name synonym)|uniprotkb:Proteasome component C7-I(gene name synonym)|uniprotkb:Macropain subunit C7-I(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770037|imex:IM-28143-32	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	refseq:NP_002785.1|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5GJR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-5689603|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000126067(gene)|ensembl:ENST00000373237(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|mint:P49721|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|dip:DIP-33848N|genbank_nucl_gi:1709762(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rogid:PvXrk6RLayQ1zqmavn1cONfA9/A9606	rigid:BI3tXBFYZrWhhIbT3YucC7rdeIA	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86TM6	uniprotkb:P25788	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	intact:EBI-348380|ensembl:ENSP00000216455|uniprotkb:Q86U83|uniprotkb:Q8N1D8|uniprotkb:Q9BS70|uniprotkb:B2RCK6	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:psa3_human(display_long)|uniprotkb:PSMA3(gene name)|psi-mi:PSMA3(display_short)|uniprotkb:PSC8(gene name synonym)|uniprotkb:Proteasome component C8(gene name synonym)|uniprotkb:Macropain subunit C8(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C8(gene name synonym)|uniprotkb:HC8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770037|imex:IM-28143-32	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	refseq:NP_002779.1|refseq:NP_687033.1|ensembl:ENSG00000100567(gene)|ensembl:ENST00000216455(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0045202"(synapse)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR037555|mint:P25788|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|rcsb pdb:5DSV|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|rcsb pdb:7E55|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|rcsb pdb:5T0H|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-174084|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-174113|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|dip:DIP-29366N|genbank_nucl_gi:130859(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rogid:9Er/PY50/GVoCr5yAPXlkfxtP0k9606	rigid:BI3tXBFYZrWhhIbT3YucC7rdeIA	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86TM6	uniprotkb:P20618	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	intact:EBI-372273|uniprotkb:Q9BWA8|ensembl:ENSP00000262193|uniprotkb:B5BU76	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:psb1_human(display_long)|uniprotkb:PSMB1(gene name)|psi-mi:PSMB1(display_short)|uniprotkb:PSC5(gene name synonym)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Macropain subunit C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym)|uniprotkb:Proteasome gamma chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770037|imex:IM-28143-32	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	ensembl:ENSG00000008018(gene)|ensembl:ENST00000262193(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|mint:P20618|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|refseq:NP_002784.1|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M2B|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5LF1|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4608870|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-983168|reactome:R-HSA-9604323|dip:DIP-31193N|genbank_nucl_gi:130853(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rogid:DfIS480BUnqbXus9/KoojdkWgw09606	rigid:BI3tXBFYZrWhhIbT3YucC7rdeIA	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86TM6	uniprotkb:P25787	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	intact:EBI-603262|uniprotkb:Q9BU45|ensembl:ENSP00000223321|intact:EBI-1237095|uniprotkb:Q6ICS6	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:psa2_human(display_long)|uniprotkb:PSMA2(gene name)|psi-mi:PSMA2(display_short)|uniprotkb:PSC3(gene name synonym)|uniprotkb:Proteasome component C3(gene name synonym)|uniprotkb:Macropain subunit C3(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C3(gene name synonym)|uniprotkb:HC3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770037|imex:IM-28143-32	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	mint:P25787|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|ensembl:ENSG00000106588(gene)|ensembl:ENST00000223321(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0009615"(response to virus)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|refseq:NP_002778.1|dip:DIP-29364N|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|genbank_nucl_gi:130850(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rogid:COncAMXXqT+zAHA/nK+7dweRg9A9606	rigid:BI3tXBFYZrWhhIbT3YucC7rdeIA	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86TM6	uniprotkb:P25786	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	intact:EBI-359352|uniprotkb:Q9BRV9|uniprotkb:A8K400|uniprotkb:Q53YE8|ensembl:ENSP00000379676	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:psa1_human(display_long)|uniprotkb:PSMA1(gene name)|psi-mi:PSMA1(display_short)|uniprotkb:PROS30(gene name synonym)|uniprotkb:PSC2(gene name synonym)|uniprotkb:Proteasome component C2(gene name synonym)|uniprotkb:Macropain subunit C2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C2(gene name synonym)|uniprotkb:Proteasome nu chain(gene name synonym)|uniprotkb:30 kDa prosomal protein(gene name synonym)|uniprotkb:HC2(gene name synonym)|uniprotkb:NU(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770037|imex:IM-28143-32	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	refseq:NP_002777.1|refseq:NP_683877.1|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000129084(gene)|ensembl:ENST00000396394(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|mint:P25786|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|dip:DIP-29369N|genbank_nucl_gi:130848(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rogid:tAADzZ1G9E/0BBeS8vybNx97v7k9606	rigid:BI3tXBFYZrWhhIbT3YucC7rdeIA	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86TM6	uniprotkb:Q9Y679	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	intact:EBI-1058701|ensembl:ENSP00000366748|uniprotkb:Q9H866|uniprotkb:Q9UNQ6|uniprotkb:Q9Y685|uniprotkb:C0H5W8	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:aup1_human(display_long)|uniprotkb:AUP1(gene name)|psi-mi:AUP1(display_short)|uniprotkb:Ancient ubiquitous protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770037|imex:IM-28143-32	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	ensembl:ENSG00000115307(gene)|ensembl:ENST00000377526(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:NP_853553.1|go:"GO:0034389"(lipid droplet organization)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061724"(lipophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:0140042"(lipid droplet formation)|go:"GO:1990044"(protein localization to lipid droplet)|interpro:IPR003892(Ubiquitin system component Cue)|rcsb pdb:2EKF|genbank_nucl_gi:12643958(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rogid:6yySfIPpRUlnm0upBDYyfBUOtIY9606	rigid:BI3tXBFYZrWhhIbT3YucC7rdeIA	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86TM6	uniprotkb:O14818	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	intact:EBI-603272|uniprotkb:Q9BR53|uniprotkb:Q9H4K5|uniprotkb:Q9UEU8|uniprotkb:B2R515|uniprotkb:Q5JXJ2|ensembl:ENSP00000359910	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:psa7_human(display_long)|uniprotkb:PSMA7(gene name)|psi-mi:PSMA7(display_short)|uniprotkb:Proteasome subunit RC6-1(gene name synonym)|uniprotkb:Proteasome subunit XAPC7(gene name synonym)|uniprotkb:HSPC(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770037|imex:IM-28143-32	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	refseq:NP_002783.1|dip:DIP-29363N|ensembl:ENSG00000101182(gene)|ensembl:ENST00000370873(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098794"(postsynapse)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035190|mint:O14818|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|genbank_nucl_gi:12643540(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rogid:J1M+b+VK02BAn2OnZISjjlmO8dc9606	rigid:BI3tXBFYZrWhhIbT3YucC7rdeIA	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86TM6	uniprotkb:P09601	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	intact:EBI-2806151|ensembl:ENSP00000216117	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:hmox1_human(display_long)|uniprotkb:HO(gene name synonym)|uniprotkb:HO1(gene name synonym)|uniprotkb:HMOX1(gene name)|psi-mi:HMOX1(display_short)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770037|imex:IM-28143-32	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	rcsb pdb:6EHA|reactome:R-HSA-189483|reactome:R-HSA-6785807|reactome:R-HSA-844456|reactome:R-HSA-917937|reactome:R-HSA-9609523|reactome:R-HSA-9660826|reactome:R-HSA-9707564|reactome:R-HSA-9707587|reactome:R-HSA-9707616|refseq:NP_002124.1|ensembl:ENSG00000100292(gene)|ensembl:ENST00000216117(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002246"(wound healing involved in inflammatory response)|go:"GO:0002686"(negative regulation of leukocyte migration)|go:"GO:0004392"("heme oxygenase (decyclizing) activity")|go:"GO:0004630"(phospholipase D activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005901"(caveola)|go:"GO:0006788"(heme oxidation)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007588"(excretion)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008219"(cell death)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010656"(negative regulation of muscle cell apoptotic process)|go:"GO:0014806"(smooth muscle hyperplasia)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032764"(negative regulation of mast cell cytokine production)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0034395"(regulation of transcription from RNA polymerase II promoter in response to iron)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035094"(response to nicotine)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043305"(negative regulation of mast cell degranulation)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0043627"(response to estrogen)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072719"(cellular response to cisplatin)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0097421"(liver regeneration)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903589"(positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1904036"(negative regulation of epithelial cell apoptotic process)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|interpro:IPR002051(Haem oxygenase)|interpro:IPR016053(Haem oxygenase-like)|interpro:IPR016084(Haem oxygenase-like, multi-helical)|interpro:IPR018207|rcsb pdb:1N3U|rcsb pdb:1N45|rcsb pdb:1NI6|rcsb pdb:1OYK|rcsb pdb:1OYL|rcsb pdb:1OZE|rcsb pdb:1OZL|rcsb pdb:1OZR|rcsb pdb:1OZW|rcsb pdb:1S13|rcsb pdb:1S8C|rcsb pdb:1T5P|rcsb pdb:1TWN|rcsb pdb:1TWR|rcsb pdb:1XJZ|rcsb pdb:1XK0|rcsb pdb:1XK1|rcsb pdb:1XK2|rcsb pdb:1XK3|rcsb pdb:3CZY|rcsb pdb:3HOK|rcsb pdb:3K4F|rcsb pdb:3TGM|rcsb pdb:4WD4|rcsb pdb:5BTQ|go:"GO:0042167"(heme catabolic process)|genbank_nucl_gi:123446(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rogid:Qrwo0mQGREIpHf3DLrvyO6DOLKM9606	rigid:BI3tXBFYZrWhhIbT3YucC7rdeIA	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86TM6	uniprotkb:P04035	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	intact:EBI-465513|uniprotkb:B7Z3Y9|uniprotkb:Q8N190|ensembl:ENSP00000287936|ensembl:ENSP00000426745|ensembl:ENSP00000505561|ensembl:ENSP00000505805|ensembl:ENSP00000506232	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:hmdh_human(display_long)|uniprotkb:HMGCR(gene name)|psi-mi:HMGCR(display_short)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770037|imex:IM-28143-32	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	refseq:NP_000850.1|refseq:NP_001124468.1|refseq:XP_011541659.1|refseq:XP_011541660.1|ensembl:ENSG00000113161(gene)|ensembl:ENST00000287936(transcript)|ensembl:ENST00000511206(transcript)|ensembl:ENST00000680940(transcript)|ensembl:ENST00000681271(transcript)|ensembl:ENST00000681410(transcript)|go:"GO:0004420"("hydroxymethylglutaryl-CoA reductase (NADPH) activity")|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0010664"(negative regulation of striated muscle cell apoptotic process)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0006743"(ubiquinone metabolic process)|go:"GO:0007568"(aging)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008299"(isoprenoid biosynthetic process)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0008542"(visual learning)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061179"(negative regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070402"(NADPH binding)|go:"GO:0070723"(response to cholesterol)|go:"GO:0120225"(coenzyme A binding)|go:"GO:1900222"(negative regulation of amyloid-beta clearance)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR002202(Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic)|interpro:IPR004554(Hydroxymethylglutaryl-CoA reductase, class I, catalytic)|interpro:IPR004816(Hydroxymethylglutaryl-CoA reductase, class I, metazoan)|interpro:IPR009023(Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding)|interpro:IPR009029(Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding)|interpro:IPR023074|interpro:IPR023076|interpro:IPR023282|rcsb pdb:1DQ8|rcsb pdb:1DQ9|rcsb pdb:1DQA|rcsb pdb:1HW8|rcsb pdb:1HW9|rcsb pdb:1HWI|rcsb pdb:1HWJ|rcsb pdb:1HWK|rcsb pdb:1HWL|rcsb pdb:2Q1L|rcsb pdb:2Q6B|rcsb pdb:2Q6C|rcsb pdb:2R4F|rcsb pdb:3BGL|rcsb pdb:3CCT|rcsb pdb:3CCW|rcsb pdb:3CCZ|rcsb pdb:3CD0|rcsb pdb:3CD5|rcsb pdb:3CD7|rcsb pdb:3CDA|rcsb pdb:3CDB|reactome:R-HSA-191273|reactome:R-HSA-1989781|reactome:R-HSA-2426168|reactome:R-HSA-9619665|genbank_nucl_gi:123343(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rogid:fXmkDPv7ThH/PSLiNUgYR6hiIpY9606	rigid:BI3tXBFYZrWhhIbT3YucC7rdeIA	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q86TM6	uniprotkb:P28070	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	intact:EBI-603350|uniprotkb:P31148|uniprotkb:Q5SZS5|uniprotkb:Q969L6|uniprotkb:B2R9L3|uniprotkb:Q6IBI4|ensembl:ENSP00000290541	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:psb4_human(display_long)|uniprotkb:PSMB4(gene name)|psi-mi:PSMB4(display_short)|uniprotkb:Macropain beta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex beta chain(gene name synonym)|uniprotkb:Proteasome chain 3(gene name synonym)|uniprotkb:26 kDa prosomal protein(gene name synonym)|uniprotkb:PROS26(gene name synonym)|uniprotkb:Proteasome beta chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770037|imex:IM-28143-32	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032	refseq:NP_002787.2|dip:DIP-33844N|ensembl:ENSG00000159377(gene)|ensembl:ENST00000290541(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR016295(Proteasome endopeptidase complex, beta subunit)|interpro:IPR023333|interpro:IPR029055|mint:P28070|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|genbank_nucl_gi:116242733(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rogid:drR+ktPXQK9ep6hs7OYb5SmQnXU9606	rigid:BI3tXBFYZrWhhIbT3YucC7rdeIA	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9P0I2	uniprotkb:Q9NPA0	intact:EBI-1054670|uniprotkb:Q53GH8|uniprotkb:Q6ZMC2|uniprotkb:B2R4Z9|ensembl:ENSP00000245046	intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5	psi-mi:emc3_human(display_long)|uniprotkb:EMC3(gene name)|psi-mi:EMC3(display_short)|uniprotkb:TMEM111(gene name synonym)|uniprotkb:Transmembrane protein 111(gene name synonym)	psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770142|imex:IM-28143-70	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060917.1|ensembl:ENSG00000125037(gene)|ensembl:ENST00000245046(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008568(Protein of unknown function DUF850, transmembrane eukaryotic)|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-8980692	ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1|genbank_nucl_gi:74752878(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:VbIl0nFhcDMIPTxmBclaIMtbVU09606	rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606	rigid:vgRNY1dhJ0h6x9ta6sjpjyAcl3w	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9P0I2	uniprotkb:Q8N766	intact:EBI-1054670|uniprotkb:Q53GH8|uniprotkb:Q6ZMC2|uniprotkb:B2R4Z9|ensembl:ENSP00000245046	intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62	psi-mi:emc3_human(display_long)|uniprotkb:EMC3(gene name)|psi-mi:EMC3(display_short)|uniprotkb:TMEM111(gene name synonym)|uniprotkb:Transmembrane protein 111(gene name synonym)	psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770142|imex:IM-28143-70	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060917.1|ensembl:ENSG00000125037(gene)|ensembl:ENST00000245046(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008568(Protein of unknown function DUF850, transmembrane eukaryotic)|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-8980692	go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1|genbank_nucl_gi:74751081(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:VbIl0nFhcDMIPTxmBclaIMtbVU09606	rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606	rigid:vgRNY1dhJ0h6x9ta6sjpjyAcl3w	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9P0I2	uniprotkb:Q15006	intact:EBI-1054670|uniprotkb:Q53GH8|uniprotkb:Q6ZMC2|uniprotkb:B2R4Z9|ensembl:ENSP00000245046	intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853	psi-mi:emc3_human(display_long)|uniprotkb:EMC3(gene name)|psi-mi:EMC3(display_short)|uniprotkb:TMEM111(gene name synonym)|uniprotkb:Transmembrane protein 111(gene name synonym)	psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770142|imex:IM-28143-70	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060917.1|ensembl:ENSG00000125037(gene)|ensembl:ENST00000245046(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008568(Protein of unknown function DUF850, transmembrane eukaryotic)|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-8980692	refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|genbank_nucl_gi:3183217(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:VbIl0nFhcDMIPTxmBclaIMtbVU09606	rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606	rigid:vgRNY1dhJ0h6x9ta6sjpjyAcl3w	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9P0I2	uniprotkb:O43402	intact:EBI-1054670|uniprotkb:Q53GH8|uniprotkb:Q6ZMC2|uniprotkb:B2R4Z9|ensembl:ENSP00000245046	intact:EBI-741841|ensembl:ENSP00000253457|uniprotkb:C9JB21	psi-mi:emc3_human(display_long)|uniprotkb:EMC3(gene name)|psi-mi:EMC3(display_short)|uniprotkb:TMEM111(gene name synonym)|uniprotkb:Transmembrane protein 111(gene name synonym)	psi-mi:emc8_human(display_long)|uniprotkb:EMC8(gene name)|psi-mi:EMC8(display_short)|uniprotkb:C16orf2(gene name synonym)|uniprotkb:C16orf4(gene name synonym)|uniprotkb:COX4AL(gene name synonym)|uniprotkb:COX4NB(gene name synonym)|uniprotkb:FAM158B(gene name synonym)|uniprotkb:NOC4(gene name synonym)|uniprotkb:Neighbor of COX4(gene name synonym)|uniprotkb:Protein FAM158B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770142|imex:IM-28143-70	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060917.1|ensembl:ENSG00000125037(gene)|ensembl:ENST00000245046(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008568(Protein of unknown function DUF850, transmembrane eukaryotic)|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-8980692	refseq:NP_006058.1|ensembl:ENSG00000131148(gene)|ensembl:ENST00000253457(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6WW7|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_001135760.1|genbank_nucl_gi:18202040(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:VbIl0nFhcDMIPTxmBclaIMtbVU09606	rogid:cGQFR1ZU2L/KgikqLELVUzplhTU9606	rigid:vgRNY1dhJ0h6x9ta6sjpjyAcl3w	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9P0I2	uniprotkb:Q9UHD9	intact:EBI-1054670|uniprotkb:Q53GH8|uniprotkb:Q6ZMC2|uniprotkb:B2R4Z9|ensembl:ENSP00000245046	intact:EBI-947187|uniprotkb:O94798|uniprotkb:Q9H3W6|uniprotkb:Q9HAZ4|uniprotkb:Q5D027|intact:EBI-28967571|ensembl:ENSP00000345195	psi-mi:emc3_human(display_long)|uniprotkb:EMC3(gene name)|psi-mi:EMC3(display_short)|uniprotkb:TMEM111(gene name synonym)|uniprotkb:Transmembrane protein 111(gene name synonym)	psi-mi:ubql2_human(display_long)|uniprotkb:UBQLN2(gene name)|psi-mi:UBQLN2(display_short)|uniprotkb:PLIC2(gene name synonym)|uniprotkb:HRIHFB2157(orf name)|uniprotkb:N4BP4(gene name synonym)|uniprotkb:Protein linking IAP with cytoskeleton 2(gene name synonym)|uniprotkb:Ubiquitin-like product Chap1/Dsk2(gene name synonym)|uniprotkb:DSK2 homolog(gene name synonym)|uniprotkb:Chap1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770142|imex:IM-28143-70	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060917.1|ensembl:ENSG00000125037(gene)|ensembl:ENST00000245046(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008568(Protein of unknown function DUF850, transmembrane eukaryotic)|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-8980692	ensembl:ENSP00000345195|refseq:NP_038472.2|dip:DIP-42116N|ensembl:ENSG00000188021(gene)|ensembl:ENST00000338222(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:1900186"(negative regulation of clathrin-dependent endocytosis)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1904021"(negative regulation of G protein-coupled receptor internalization)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028430|interpro:IPR029071|mint:Q9UHD9|rcsb pdb:1J8C|rcsb pdb:2NBV|rcsb pdb:6MUN|reactome:R-HSA-8856825|genbank_nucl_gi:124056593(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:VbIl0nFhcDMIPTxmBclaIMtbVU09606	rogid:tElcz7gHFkKFVDTz3PXeNcaBP7U9606	rigid:vgRNY1dhJ0h6x9ta6sjpjyAcl3w	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9P0I2	uniprotkb:Q9Y3B6	intact:EBI-1054670|uniprotkb:Q53GH8|uniprotkb:Q6ZMC2|uniprotkb:B2R4Z9|ensembl:ENSP00000245046	intact:EBI-748366|uniprotkb:Q9BUM3|uniprotkb:D3DS60|ensembl:ENSP00000216799|ensembl:ENSP00000403210|ensembl:ENSP00000494976|ensembl:ENSP00000495623	psi-mi:emc3_human(display_long)|uniprotkb:EMC3(gene name)|psi-mi:EMC3(display_short)|uniprotkb:TMEM111(gene name synonym)|uniprotkb:Transmembrane protein 111(gene name synonym)	psi-mi:emc9_human(display_long)|uniprotkb:EMC9(gene name)|psi-mi:EMC9(display_short)|uniprotkb:C14orf122(gene name synonym)|uniprotkb:FAM158A(gene name synonym)|uniprotkb:Protein FAM158A(gene name synonym)|uniprotkb:CGI-112(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770142|imex:IM-28143-70	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060917.1|ensembl:ENSG00000125037(gene)|ensembl:ENST00000245046(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008568(Protein of unknown function DUF850, transmembrane eukaryotic)|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-8980692	refseq:NP_057133.2|refseq:XP_005267778.1|ensembl:ENSG00000100908(gene)|ensembl:ENSG00000285377(gene)|ensembl:ENST00000216799(transcript)|ensembl:ENST00000419198(transcript)|ensembl:ENST00000642147(transcript)|ensembl:ENST00000646772(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6Y4L|rcsb pdb:6Z3W|genbank_nucl_gi:116241305(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:VbIl0nFhcDMIPTxmBclaIMtbVU09606	rogid:ZMbNxmOKb2r2KzWdB5JF/kGPSaU9606	rigid:vgRNY1dhJ0h6x9ta6sjpjyAcl3w	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UBU6	uniprotkb:Q96DZ1	intact:EBI-6309101|intact:EBI-28967558|ensembl:ENSP00000259963|uniprotkb:B2R725	intact:EBI-1023677|uniprotkb:O95901|uniprotkb:Q6UWN7|uniprotkb:Q9NUY7|uniprotkb:Q9UQL4|uniprotkb:B2RDB4|ensembl:ENSP00000185150|uniprotkb:B5MC72	psi-mi:fa8a1_human(display_long)|uniprotkb:FAM8A1(gene name)|psi-mi:FAM8A1(display_short)|uniprotkb:AHCP(gene name synonym)|uniprotkb:Autosomal highly conserved protein(gene name synonym)	psi-mi:erlec_human(display_long)|uniprotkb:ER lectin(gene name synonym)|uniprotkb:ERLEC1(gene name)|psi-mi:ERLEC1(display_short)|uniprotkb:XTP3TPB(gene name synonym)|uniprotkb:UNQ1878/PRO4321(orf name)|uniprotkb:C2orf30(gene name synonym)|uniprotkb:XTP3-transactivated gene B protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770310|imex:IM-28143-72	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000259963|ensembl:ENSG00000137414(gene)|ensembl:ENST00000259963(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|interpro:IPR010432(RDD)|interpro:IPR039871|refseq:NP_057339.1	refseq:NP_001120870.1|refseq:NP_056516.2|ensembl:ENSG00000068912(gene)|ensembl:ENST00000185150(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR044865|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|refseq:NP_001120869.1|genbank_nucl_gi:74731510(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:0HV6qye10bMGdnt9CiGztIacrHM9606	rogid:eBOyI1TfCgExBrXLxSwlUZ05NXs9606	rigid:g308d1EBE6sKGjBbh/6Veb590TA	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UBU6	uniprotkb:Q9UBV2	intact:EBI-6309101|intact:EBI-28967558|ensembl:ENSP00000259963|uniprotkb:B2R725	intact:EBI-358766|uniprotkb:Q6UWT6|uniprotkb:Q9P1T9|uniprotkb:Q9UHK7|ensembl:ENSP00000337053	psi-mi:fa8a1_human(display_long)|uniprotkb:FAM8A1(gene name)|psi-mi:FAM8A1(display_short)|uniprotkb:AHCP(gene name synonym)|uniprotkb:Autosomal highly conserved protein(gene name synonym)	psi-mi:se1l1_human(display_long)|uniprotkb:SEL1L(gene name)|psi-mi:SEL1L(display_short)|uniprotkb:TSA305(gene name synonym)|uniprotkb:UNQ128/PRO1063(orf name)|uniprotkb:Suppressor of lin-12-like protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770310|imex:IM-28143-72	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000259963|ensembl:ENSG00000137414(gene)|ensembl:ENST00000259963(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|interpro:IPR010432(RDD)|interpro:IPR039871|refseq:NP_057339.1	refseq:NP_001231913.1|refseq:NP_005056.3|ensembl:ENSG00000071537(gene)|ensembl:ENST00000336735(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0050821"(protein stabilization)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|mint:Q9UBV2|reactome:R-HSA-1912420|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-46259N|genbank_nucl_gi:62512184(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:0HV6qye10bMGdnt9CiGztIacrHM9606	rogid:eufE+8nfcHK8CDl+AQ5G+3NtL+09606	rigid:g308d1EBE6sKGjBbh/6Veb590TA	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UBU6	uniprotkb:Q6IMN6	intact:EBI-6309101|intact:EBI-28967558|ensembl:ENSP00000259963|uniprotkb:B2R725	intact:EBI-6918449|uniprotkb:E4NKG2|uniprotkb:Q149P6|uniprotkb:Q149P7|uniprotkb:Q6IMN5|uniprotkb:Q7Z371|uniprotkb:Q8TE70|uniprotkb:Q8TE71|uniprotkb:Q96RN6|uniprotkb:Q9H667|uniprotkb:Q9HAL4	psi-mi:fa8a1_human(display_long)|uniprotkb:FAM8A1(gene name)|psi-mi:FAM8A1(display_short)|uniprotkb:AHCP(gene name synonym)|uniprotkb:Autosomal highly conserved protein(gene name synonym)	psi-mi:capr2_human(display_long)|uniprotkb:CAPRIN2(gene name)|psi-mi:CAPRIN2(display_short)|uniprotkb:C1QDC1(gene name synonym)|uniprotkb:EEG1(gene name synonym)|uniprotkb:KIAA1873(gene name synonym)|uniprotkb:RNG140(gene name synonym)|uniprotkb:C1q domain-containing protein 1(gene name synonym)|uniprotkb:Cytoplasmic activation/proliferation-associated protein 2(gene name synonym)|uniprotkb:Gastric cancer multidrug resistance-associated protein(gene name synonym)|uniprotkb:Protein EEG-1(gene name synonym)|uniprotkb:RNA granule protein 140(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770310|imex:IM-28143-72	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000259963|ensembl:ENSG00000137414(gene)|ensembl:ENST00000259963(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|interpro:IPR010432(RDD)|interpro:IPR039871|refseq:NP_057339.1	rcsb pdb:4OUL|rcsb pdb:4OUM|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0043235"(receptor complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0017148"(negative regulation of translation)|interpro:IPR028816|refseq:NP_001306771.1|refseq:NP_001306772.1|interpro:IPR001073(Complement C1q protein)|interpro:IPR022070|interpro:IPR008983(Tumour necrosis factor-like)|refseq:NP_001002259.1|refseq:NP_001193785.1|refseq:NP_076414.2|refseq:NP_115532.3|refseq:XP_006719210.1|rcsb pdb:5J97|interpro:IPR041637|genbank_nucl_gi:50428931(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:0HV6qye10bMGdnt9CiGztIacrHM9606	rogid:doFlseJcb6jzptDJuo58S3EOO309606	rigid:g308d1EBE6sKGjBbh/6Veb590TA	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UBU6	uniprotkb:Q13438	intact:EBI-6309101|intact:EBI-28967558|ensembl:ENSP00000259963|uniprotkb:B2R725	intact:EBI-725454|intact:EBI-1174342|uniprotkb:A6NDD1|uniprotkb:A6NFR7|uniprotkb:A6NLB2|uniprotkb:A8K5Q9|uniprotkb:B4DPX1|uniprotkb:B4E1I6|uniprotkb:E7ENT8|uniprotkb:F8VUH2|uniprotkb:O00579|uniprotkb:Q6IBL2|uniprotkb:Q8IZ58|uniprotkb:Q9BW99|uniprotkb:B4DE28|ensembl:ENSP00000318165|uniprotkb:E7EW91|uniprotkb:G3XA88	psi-mi:fa8a1_human(display_long)|uniprotkb:FAM8A1(gene name)|psi-mi:FAM8A1(display_short)|uniprotkb:AHCP(gene name synonym)|uniprotkb:Autosomal highly conserved protein(gene name synonym)	psi-mi:os9_human(display_long)|uniprotkb:OS9(gene name)|psi-mi:OS9(display_short)|uniprotkb:Amplified in osteosarcoma 9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770310|imex:IM-28143-72	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000259963|ensembl:ENSG00000137414(gene)|ensembl:ENST00000259963(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|interpro:IPR010432(RDD)|interpro:IPR039871|refseq:NP_057339.1	refseq:NP_006803.1|refseq:NP_001017956.1|refseq:NP_001017957.1|refseq:NP_001017958.1|refseq:NP_001248349.1|refseq:NP_001248350.1|refseq:NP_001248351.1|refseq:NP_001248352.1|ensembl:ENSG00000135506(gene)|ensembl:ENST00000315970(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0002020"(protease binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006605"(protein targeting)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|interpro:IPR044865|rcsb pdb:3AIH|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-37493N|genbank_nucl_gi:3024310(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:0HV6qye10bMGdnt9CiGztIacrHM9606	rogid:Ntc3geE7th+rBeIp0MxuUuu/28Y9606	rigid:g308d1EBE6sKGjBbh/6Veb590TA	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UBU6	uniprotkb:Q86TM6	intact:EBI-6309101|intact:EBI-28967558|ensembl:ENSP00000259963|uniprotkb:B2R725	intact:EBI-947849|uniprotkb:Q8N3K3|uniprotkb:Q8N6E8|uniprotkb:Q96JL5|uniprotkb:Q96PK3|ensembl:ENSP00000366395	psi-mi:fa8a1_human(display_long)|uniprotkb:FAM8A1(gene name)|psi-mi:FAM8A1(display_short)|uniprotkb:AHCP(gene name synonym)|uniprotkb:Autosomal highly conserved protein(gene name synonym)	psi-mi:syvn1_human(display_long)|uniprotkb:Synovial apoptosis inhibitor 1(gene name synonym)|uniprotkb:SYVN1(gene name)|psi-mi:SYVN1(display_short)|uniprotkb:HRD1(gene name synonym)|uniprotkb:KIAA1810(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase synoviolin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770310|imex:IM-28143-72	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000259963|ensembl:ENSG00000137414(gene)|ensembl:ENST00000259963(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|interpro:IPR010432(RDD)|interpro:IPR039871|refseq:NP_057339.1	refseq:NP_115807.1|refseq:NP_757385.1|refseq:XP_011543605.1|dip:DIP-43982N|ensembl:ENSG00000162298(gene)|ensembl:ENST00000377190(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002327"(immature B cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032832|mint:Q86TM6|rcsb pdb:6A3Z|reactome:R-HSA-381038|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-901032|genbank_nucl_gi:27436925(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:0HV6qye10bMGdnt9CiGztIacrHM9606	rogid:O4/BJg+TtC9t/YmKWsf4FrSW8yo9606	rigid:g308d1EBE6sKGjBbh/6Veb590TA	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N4V1	uniprotkb:Q9NPA0	intact:EBI-6163737|ensembl:ENSP00000306220|ensembl:ENSP00000505226|uniprotkb:B2R625|uniprotkb:B4DIY3|uniprotkb:D3DWG7|uniprotkb:Q5JPP7	intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5	psi-mi:emc5_human(display_long)|uniprotkb:MMGT1(gene name)|psi-mi:MMGT1(display_short)|uniprotkb:TMEM32(gene name synonym)|uniprotkb:Transmembrane protein 32(gene name synonym)|uniprotkb:EMC5(gene name synonym)|uniprotkb:Membrane magnesium transporter 1(gene name synonym)	psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770340|imex:IM-28143-90	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-5223345|ensembl:ENSG00000169446(gene)|ensembl:ENST00000305963(transcript)|ensembl:ENST00000679621(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|refseq:NP_775741.1|refseq:NP_001316929.1	ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1|genbank_nucl_gi:74752878(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:Kq+VEYt+fwoOsEfcgZ1K1vkFFN49606	rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606	rigid:9YI/7XrP7uPt1T4cTeYmU0Q0hGs	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N4V1	uniprotkb:Q8N766	intact:EBI-6163737|ensembl:ENSP00000306220|ensembl:ENSP00000505226|uniprotkb:B2R625|uniprotkb:B4DIY3|uniprotkb:D3DWG7|uniprotkb:Q5JPP7	intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62	psi-mi:emc5_human(display_long)|uniprotkb:MMGT1(gene name)|psi-mi:MMGT1(display_short)|uniprotkb:TMEM32(gene name synonym)|uniprotkb:Transmembrane protein 32(gene name synonym)|uniprotkb:EMC5(gene name synonym)|uniprotkb:Membrane magnesium transporter 1(gene name synonym)	psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770340|imex:IM-28143-90	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-5223345|ensembl:ENSG00000169446(gene)|ensembl:ENST00000305963(transcript)|ensembl:ENST00000679621(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|refseq:NP_775741.1|refseq:NP_001316929.1	go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1|genbank_nucl_gi:74751081(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:Kq+VEYt+fwoOsEfcgZ1K1vkFFN49606	rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606	rigid:9YI/7XrP7uPt1T4cTeYmU0Q0hGs	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N4V1	uniprotkb:Q9BV81	intact:EBI-6163737|ensembl:ENSP00000306220|ensembl:ENSP00000505226|uniprotkb:B2R625|uniprotkb:B4DIY3|uniprotkb:D3DWG7|uniprotkb:Q5JPP7	intact:EBI-2820492|ensembl:ENSP00000248378|ensembl:ENSP00000380322	psi-mi:emc5_human(display_long)|uniprotkb:MMGT1(gene name)|psi-mi:MMGT1(display_short)|uniprotkb:TMEM32(gene name synonym)|uniprotkb:Transmembrane protein 32(gene name synonym)|uniprotkb:EMC5(gene name synonym)|uniprotkb:Membrane magnesium transporter 1(gene name synonym)	psi-mi:emc6_human(display_long)|uniprotkb:EMC6(gene name)|psi-mi:EMC6(display_short)|uniprotkb:TMEM93(gene name synonym)|uniprotkb:Transmembrane protein 93(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770340|imex:IM-28143-90	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-5223345|ensembl:ENSG00000169446(gene)|ensembl:ENST00000305963(transcript)|ensembl:ENST00000679621(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|refseq:NP_775741.1|refseq:NP_001316929.1	refseq:NP_001014764.1|refseq:NP_112588.1|ensembl:ENSG00000127774(gene)|ensembl:ENST00000248378(transcript)|ensembl:ENST00000397133(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0097631"(integral component of omegasome membrane)|interpro:IPR008504(Protein of unknown function DUF786)|interpro:IPR029008|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|go:"GO:0072546"(EMC complex)|genbank_nucl_gi:74733294(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:Kq+VEYt+fwoOsEfcgZ1K1vkFFN49606	rogid:GPnTCJqAA2eIiiP17pgtIhGnpsA9606	rigid:9YI/7XrP7uPt1T4cTeYmU0Q0hGs	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N4V1	uniprotkb:Q5UCC4	intact:EBI-6163737|ensembl:ENSP00000306220|ensembl:ENSP00000505226|uniprotkb:B2R625|uniprotkb:B4DIY3|uniprotkb:D3DWG7|uniprotkb:Q5JPP7	intact:EBI-11284388|uniprotkb:Q5UCC6|uniprotkb:Q69YT5|uniprotkb:Q6UWP3|uniprotkb:Q86YL4|uniprotkb:Q8N541|ensembl:ENSP00000334037	psi-mi:emc5_human(display_long)|uniprotkb:MMGT1(gene name)|psi-mi:MMGT1(display_short)|uniprotkb:TMEM32(gene name synonym)|uniprotkb:Transmembrane protein 32(gene name synonym)|uniprotkb:EMC5(gene name synonym)|uniprotkb:Membrane magnesium transporter 1(gene name synonym)	psi-mi:emc10_human(display_long)|uniprotkb:EMC10(gene name)|psi-mi:EMC10(display_short)|uniprotkb:C19orf63(gene name synonym)|uniprotkb:Hematopoietic signal peptide-containing membrane domain-containing protein 1(gene name synonym)|uniprotkb:INM02(gene name synonym)|uniprotkb:UNQ764/PRO1556(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770340|imex:IM-28143-90	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-5223345|ensembl:ENSG00000169446(gene)|ensembl:ENST00000305963(transcript)|ensembl:ENST00000679621(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|refseq:NP_775741.1|refseq:NP_001316929.1	refseq:NP_778233.4|refseq:NP_996261.1|ensembl:ENSG00000161671(gene)|ensembl:ENST00000334976(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005576"(extracellular region)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR029615|mint:Q5UCC4|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|genbank_nucl_gi:74708213(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:Kq+VEYt+fwoOsEfcgZ1K1vkFFN49606	rogid:NEJjkw5uEJnzNUW7MkZIm/ELpA89606	rigid:9YI/7XrP7uPt1T4cTeYmU0Q0hGs	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N4V1	uniprotkb:Q9P0I2	intact:EBI-6163737|ensembl:ENSP00000306220|ensembl:ENSP00000505226|uniprotkb:B2R625|uniprotkb:B4DIY3|uniprotkb:D3DWG7|uniprotkb:Q5JPP7	intact:EBI-1054670|uniprotkb:Q53GH8|uniprotkb:Q6ZMC2|uniprotkb:B2R4Z9|ensembl:ENSP00000245046	psi-mi:emc5_human(display_long)|uniprotkb:MMGT1(gene name)|psi-mi:MMGT1(display_short)|uniprotkb:TMEM32(gene name synonym)|uniprotkb:Transmembrane protein 32(gene name synonym)|uniprotkb:EMC5(gene name synonym)|uniprotkb:Membrane magnesium transporter 1(gene name synonym)	psi-mi:emc3_human(display_long)|uniprotkb:EMC3(gene name)|psi-mi:EMC3(display_short)|uniprotkb:TMEM111(gene name synonym)|uniprotkb:Transmembrane protein 111(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770340|imex:IM-28143-90	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-5223345|ensembl:ENSG00000169446(gene)|ensembl:ENST00000305963(transcript)|ensembl:ENST00000679621(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|refseq:NP_775741.1|refseq:NP_001316929.1	refseq:NP_060917.1|ensembl:ENSG00000125037(gene)|ensembl:ENST00000245046(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008568(Protein of unknown function DUF850, transmembrane eukaryotic)|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-8980692|genbank_nucl_gi:71153383(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:Kq+VEYt+fwoOsEfcgZ1K1vkFFN49606	rogid:VbIl0nFhcDMIPTxmBclaIMtbVU09606	rigid:9YI/7XrP7uPt1T4cTeYmU0Q0hGs	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N4V1	uniprotkb:Q15006	intact:EBI-6163737|ensembl:ENSP00000306220|ensembl:ENSP00000505226|uniprotkb:B2R625|uniprotkb:B4DIY3|uniprotkb:D3DWG7|uniprotkb:Q5JPP7	intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853	psi-mi:emc5_human(display_long)|uniprotkb:MMGT1(gene name)|psi-mi:MMGT1(display_short)|uniprotkb:TMEM32(gene name synonym)|uniprotkb:Transmembrane protein 32(gene name synonym)|uniprotkb:EMC5(gene name synonym)|uniprotkb:Membrane magnesium transporter 1(gene name synonym)	psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770340|imex:IM-28143-90	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-5223345|ensembl:ENSG00000169446(gene)|ensembl:ENST00000305963(transcript)|ensembl:ENST00000679621(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|refseq:NP_775741.1|refseq:NP_001316929.1	refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|genbank_nucl_gi:3183217(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:Kq+VEYt+fwoOsEfcgZ1K1vkFFN49606	rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606	rigid:9YI/7XrP7uPt1T4cTeYmU0Q0hGs	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N4V1	uniprotkb:O43402	intact:EBI-6163737|ensembl:ENSP00000306220|ensembl:ENSP00000505226|uniprotkb:B2R625|uniprotkb:B4DIY3|uniprotkb:D3DWG7|uniprotkb:Q5JPP7	intact:EBI-741841|ensembl:ENSP00000253457|uniprotkb:C9JB21	psi-mi:emc5_human(display_long)|uniprotkb:MMGT1(gene name)|psi-mi:MMGT1(display_short)|uniprotkb:TMEM32(gene name synonym)|uniprotkb:Transmembrane protein 32(gene name synonym)|uniprotkb:EMC5(gene name synonym)|uniprotkb:Membrane magnesium transporter 1(gene name synonym)	psi-mi:emc8_human(display_long)|uniprotkb:EMC8(gene name)|psi-mi:EMC8(display_short)|uniprotkb:C16orf2(gene name synonym)|uniprotkb:C16orf4(gene name synonym)|uniprotkb:COX4AL(gene name synonym)|uniprotkb:COX4NB(gene name synonym)|uniprotkb:FAM158B(gene name synonym)|uniprotkb:NOC4(gene name synonym)|uniprotkb:Neighbor of COX4(gene name synonym)|uniprotkb:Protein FAM158B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770340|imex:IM-28143-90	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-5223345|ensembl:ENSG00000169446(gene)|ensembl:ENST00000305963(transcript)|ensembl:ENST00000679621(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|refseq:NP_775741.1|refseq:NP_001316929.1	refseq:NP_006058.1|ensembl:ENSG00000131148(gene)|ensembl:ENST00000253457(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6WW7|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_001135760.1|genbank_nucl_gi:18202040(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:Kq+VEYt+fwoOsEfcgZ1K1vkFFN49606	rogid:cGQFR1ZU2L/KgikqLELVUzplhTU9606	rigid:9YI/7XrP7uPt1T4cTeYmU0Q0hGs	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N4V1	uniprotkb:Q9UHD9	intact:EBI-6163737|ensembl:ENSP00000306220|ensembl:ENSP00000505226|uniprotkb:B2R625|uniprotkb:B4DIY3|uniprotkb:D3DWG7|uniprotkb:Q5JPP7	intact:EBI-947187|uniprotkb:O94798|uniprotkb:Q9H3W6|uniprotkb:Q9HAZ4|uniprotkb:Q5D027|intact:EBI-28967571|ensembl:ENSP00000345195	psi-mi:emc5_human(display_long)|uniprotkb:MMGT1(gene name)|psi-mi:MMGT1(display_short)|uniprotkb:TMEM32(gene name synonym)|uniprotkb:Transmembrane protein 32(gene name synonym)|uniprotkb:EMC5(gene name synonym)|uniprotkb:Membrane magnesium transporter 1(gene name synonym)	psi-mi:ubql2_human(display_long)|uniprotkb:UBQLN2(gene name)|psi-mi:UBQLN2(display_short)|uniprotkb:PLIC2(gene name synonym)|uniprotkb:HRIHFB2157(orf name)|uniprotkb:N4BP4(gene name synonym)|uniprotkb:Protein linking IAP with cytoskeleton 2(gene name synonym)|uniprotkb:Ubiquitin-like product Chap1/Dsk2(gene name synonym)|uniprotkb:DSK2 homolog(gene name synonym)|uniprotkb:Chap1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770340|imex:IM-28143-90	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-5223345|ensembl:ENSG00000169446(gene)|ensembl:ENST00000305963(transcript)|ensembl:ENST00000679621(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|refseq:NP_775741.1|refseq:NP_001316929.1	ensembl:ENSP00000345195|refseq:NP_038472.2|dip:DIP-42116N|ensembl:ENSG00000188021(gene)|ensembl:ENST00000338222(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:1900186"(negative regulation of clathrin-dependent endocytosis)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1904021"(negative regulation of G protein-coupled receptor internalization)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028430|interpro:IPR029071|mint:Q9UHD9|rcsb pdb:1J8C|rcsb pdb:2NBV|rcsb pdb:6MUN|reactome:R-HSA-8856825|genbank_nucl_gi:124056593(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:Kq+VEYt+fwoOsEfcgZ1K1vkFFN49606	rogid:tElcz7gHFkKFVDTz3PXeNcaBP7U9606	rigid:9YI/7XrP7uPt1T4cTeYmU0Q0hGs	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N4V1	uniprotkb:Q9Y3B6	intact:EBI-6163737|ensembl:ENSP00000306220|ensembl:ENSP00000505226|uniprotkb:B2R625|uniprotkb:B4DIY3|uniprotkb:D3DWG7|uniprotkb:Q5JPP7	intact:EBI-748366|uniprotkb:Q9BUM3|uniprotkb:D3DS60|ensembl:ENSP00000216799|ensembl:ENSP00000403210|ensembl:ENSP00000494976|ensembl:ENSP00000495623	psi-mi:emc5_human(display_long)|uniprotkb:MMGT1(gene name)|psi-mi:MMGT1(display_short)|uniprotkb:TMEM32(gene name synonym)|uniprotkb:Transmembrane protein 32(gene name synonym)|uniprotkb:EMC5(gene name synonym)|uniprotkb:Membrane magnesium transporter 1(gene name synonym)	psi-mi:emc9_human(display_long)|uniprotkb:EMC9(gene name)|psi-mi:EMC9(display_short)|uniprotkb:C14orf122(gene name synonym)|uniprotkb:FAM158A(gene name synonym)|uniprotkb:Protein FAM158A(gene name synonym)|uniprotkb:CGI-112(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770340|imex:IM-28143-90	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-5223345|ensembl:ENSG00000169446(gene)|ensembl:ENST00000305963(transcript)|ensembl:ENST00000679621(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|refseq:NP_775741.1|refseq:NP_001316929.1	refseq:NP_057133.2|refseq:XP_005267778.1|ensembl:ENSG00000100908(gene)|ensembl:ENSG00000285377(gene)|ensembl:ENST00000216799(transcript)|ensembl:ENST00000419198(transcript)|ensembl:ENST00000642147(transcript)|ensembl:ENST00000646772(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6Y4L|rcsb pdb:6Z3W|genbank_nucl_gi:116241305(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:Kq+VEYt+fwoOsEfcgZ1K1vkFFN49606	rogid:ZMbNxmOKb2r2KzWdB5JF/kGPSaU9606	rigid:9YI/7XrP7uPt1T4cTeYmU0Q0hGs	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O43402	uniprotkb:Q8N4V1	intact:EBI-741841|ensembl:ENSP00000253457|uniprotkb:C9JB21	intact:EBI-6163737|ensembl:ENSP00000306220|ensembl:ENSP00000505226|uniprotkb:B2R625|uniprotkb:B4DIY3|uniprotkb:D3DWG7|uniprotkb:Q5JPP7	psi-mi:emc8_human(display_long)|uniprotkb:EMC8(gene name)|psi-mi:EMC8(display_short)|uniprotkb:C16orf2(gene name synonym)|uniprotkb:C16orf4(gene name synonym)|uniprotkb:COX4AL(gene name synonym)|uniprotkb:COX4NB(gene name synonym)|uniprotkb:FAM158B(gene name synonym)|uniprotkb:NOC4(gene name synonym)|uniprotkb:Neighbor of COX4(gene name synonym)|uniprotkb:Protein FAM158B(gene name synonym)	psi-mi:emc5_human(display_long)|uniprotkb:MMGT1(gene name)|psi-mi:MMGT1(display_short)|uniprotkb:TMEM32(gene name synonym)|uniprotkb:Transmembrane protein 32(gene name synonym)|uniprotkb:EMC5(gene name synonym)|uniprotkb:Membrane magnesium transporter 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770373|imex:IM-28143-52	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006058.1|ensembl:ENSG00000131148(gene)|ensembl:ENST00000253457(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6WW7|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_001135760.1	go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-5223345|ensembl:ENSG00000169446(gene)|ensembl:ENST00000305963(transcript)|ensembl:ENST00000679621(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|refseq:NP_775741.1|refseq:NP_001316929.1|genbank_nucl_gi:74751006(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:cGQFR1ZU2L/KgikqLELVUzplhTU9606	rogid:Kq+VEYt+fwoOsEfcgZ1K1vkFFN49606	rigid:LcnDVnfPsJRIl0sJ1qaIWf6qVNM	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O43402	uniprotkb:Q5UCC4	intact:EBI-741841|ensembl:ENSP00000253457|uniprotkb:C9JB21	intact:EBI-11284388|uniprotkb:Q5UCC6|uniprotkb:Q69YT5|uniprotkb:Q6UWP3|uniprotkb:Q86YL4|uniprotkb:Q8N541|ensembl:ENSP00000334037	psi-mi:emc8_human(display_long)|uniprotkb:EMC8(gene name)|psi-mi:EMC8(display_short)|uniprotkb:C16orf2(gene name synonym)|uniprotkb:C16orf4(gene name synonym)|uniprotkb:COX4AL(gene name synonym)|uniprotkb:COX4NB(gene name synonym)|uniprotkb:FAM158B(gene name synonym)|uniprotkb:NOC4(gene name synonym)|uniprotkb:Neighbor of COX4(gene name synonym)|uniprotkb:Protein FAM158B(gene name synonym)	psi-mi:emc10_human(display_long)|uniprotkb:EMC10(gene name)|psi-mi:EMC10(display_short)|uniprotkb:C19orf63(gene name synonym)|uniprotkb:Hematopoietic signal peptide-containing membrane domain-containing protein 1(gene name synonym)|uniprotkb:INM02(gene name synonym)|uniprotkb:UNQ764/PRO1556(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770373|imex:IM-28143-52	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006058.1|ensembl:ENSG00000131148(gene)|ensembl:ENST00000253457(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6WW7|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_001135760.1	refseq:NP_778233.4|refseq:NP_996261.1|ensembl:ENSG00000161671(gene)|ensembl:ENST00000334976(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005576"(extracellular region)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR029615|mint:Q5UCC4|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|genbank_nucl_gi:89886466(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:cGQFR1ZU2L/KgikqLELVUzplhTU9606	rogid:NEJjkw5uEJnzNUW7MkZIm/ELpA89606	rigid:LcnDVnfPsJRIl0sJ1qaIWf6qVNM	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O43402	uniprotkb:Q9NPA0	intact:EBI-741841|ensembl:ENSP00000253457|uniprotkb:C9JB21	intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5	psi-mi:emc8_human(display_long)|uniprotkb:EMC8(gene name)|psi-mi:EMC8(display_short)|uniprotkb:C16orf2(gene name synonym)|uniprotkb:C16orf4(gene name synonym)|uniprotkb:COX4AL(gene name synonym)|uniprotkb:COX4NB(gene name synonym)|uniprotkb:FAM158B(gene name synonym)|uniprotkb:NOC4(gene name synonym)|uniprotkb:Neighbor of COX4(gene name synonym)|uniprotkb:Protein FAM158B(gene name synonym)	psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770373|imex:IM-28143-52	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006058.1|ensembl:ENSG00000131148(gene)|ensembl:ENST00000253457(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6WW7|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_001135760.1	ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1|genbank_nucl_gi:74752878(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:cGQFR1ZU2L/KgikqLELVUzplhTU9606	rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606	rigid:LcnDVnfPsJRIl0sJ1qaIWf6qVNM	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O43402	uniprotkb:Q8N766	intact:EBI-741841|ensembl:ENSP00000253457|uniprotkb:C9JB21	intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62	psi-mi:emc8_human(display_long)|uniprotkb:EMC8(gene name)|psi-mi:EMC8(display_short)|uniprotkb:C16orf2(gene name synonym)|uniprotkb:C16orf4(gene name synonym)|uniprotkb:COX4AL(gene name synonym)|uniprotkb:COX4NB(gene name synonym)|uniprotkb:FAM158B(gene name synonym)|uniprotkb:NOC4(gene name synonym)|uniprotkb:Neighbor of COX4(gene name synonym)|uniprotkb:Protein FAM158B(gene name synonym)	psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770373|imex:IM-28143-52	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006058.1|ensembl:ENSG00000131148(gene)|ensembl:ENST00000253457(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6WW7|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_001135760.1	go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1|genbank_nucl_gi:74751081(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:cGQFR1ZU2L/KgikqLELVUzplhTU9606	rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606	rigid:LcnDVnfPsJRIl0sJ1qaIWf6qVNM	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O43402	uniprotkb:Q9BV81	intact:EBI-741841|ensembl:ENSP00000253457|uniprotkb:C9JB21	intact:EBI-2820492|ensembl:ENSP00000248378|ensembl:ENSP00000380322	psi-mi:emc8_human(display_long)|uniprotkb:EMC8(gene name)|psi-mi:EMC8(display_short)|uniprotkb:C16orf2(gene name synonym)|uniprotkb:C16orf4(gene name synonym)|uniprotkb:COX4AL(gene name synonym)|uniprotkb:COX4NB(gene name synonym)|uniprotkb:FAM158B(gene name synonym)|uniprotkb:NOC4(gene name synonym)|uniprotkb:Neighbor of COX4(gene name synonym)|uniprotkb:Protein FAM158B(gene name synonym)	psi-mi:emc6_human(display_long)|uniprotkb:EMC6(gene name)|psi-mi:EMC6(display_short)|uniprotkb:TMEM93(gene name synonym)|uniprotkb:Transmembrane protein 93(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770373|imex:IM-28143-52	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006058.1|ensembl:ENSG00000131148(gene)|ensembl:ENST00000253457(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6WW7|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_001135760.1	refseq:NP_001014764.1|refseq:NP_112588.1|ensembl:ENSG00000127774(gene)|ensembl:ENST00000248378(transcript)|ensembl:ENST00000397133(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0097631"(integral component of omegasome membrane)|interpro:IPR008504(Protein of unknown function DUF786)|interpro:IPR029008|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|go:"GO:0072546"(EMC complex)|genbank_nucl_gi:74733294(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:cGQFR1ZU2L/KgikqLELVUzplhTU9606	rogid:GPnTCJqAA2eIiiP17pgtIhGnpsA9606	rigid:LcnDVnfPsJRIl0sJ1qaIWf6qVNM	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O43402	uniprotkb:Q9P0I2	intact:EBI-741841|ensembl:ENSP00000253457|uniprotkb:C9JB21	intact:EBI-1054670|uniprotkb:Q53GH8|uniprotkb:Q6ZMC2|uniprotkb:B2R4Z9|ensembl:ENSP00000245046	psi-mi:emc8_human(display_long)|uniprotkb:EMC8(gene name)|psi-mi:EMC8(display_short)|uniprotkb:C16orf2(gene name synonym)|uniprotkb:C16orf4(gene name synonym)|uniprotkb:COX4AL(gene name synonym)|uniprotkb:COX4NB(gene name synonym)|uniprotkb:FAM158B(gene name synonym)|uniprotkb:NOC4(gene name synonym)|uniprotkb:Neighbor of COX4(gene name synonym)|uniprotkb:Protein FAM158B(gene name synonym)	psi-mi:emc3_human(display_long)|uniprotkb:EMC3(gene name)|psi-mi:EMC3(display_short)|uniprotkb:TMEM111(gene name synonym)|uniprotkb:Transmembrane protein 111(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770373|imex:IM-28143-52	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006058.1|ensembl:ENSG00000131148(gene)|ensembl:ENST00000253457(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6WW7|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_001135760.1	refseq:NP_060917.1|ensembl:ENSG00000125037(gene)|ensembl:ENST00000245046(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008568(Protein of unknown function DUF850, transmembrane eukaryotic)|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-8980692|genbank_nucl_gi:71153383(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:cGQFR1ZU2L/KgikqLELVUzplhTU9606	rogid:VbIl0nFhcDMIPTxmBclaIMtbVU09606	rigid:LcnDVnfPsJRIl0sJ1qaIWf6qVNM	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O43402	uniprotkb:Q15006	intact:EBI-741841|ensembl:ENSP00000253457|uniprotkb:C9JB21	intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853	psi-mi:emc8_human(display_long)|uniprotkb:EMC8(gene name)|psi-mi:EMC8(display_short)|uniprotkb:C16orf2(gene name synonym)|uniprotkb:C16orf4(gene name synonym)|uniprotkb:COX4AL(gene name synonym)|uniprotkb:COX4NB(gene name synonym)|uniprotkb:FAM158B(gene name synonym)|uniprotkb:NOC4(gene name synonym)|uniprotkb:Neighbor of COX4(gene name synonym)|uniprotkb:Protein FAM158B(gene name synonym)	psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770373|imex:IM-28143-52	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006058.1|ensembl:ENSG00000131148(gene)|ensembl:ENST00000253457(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6WW7|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_001135760.1	refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|genbank_nucl_gi:3183217(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:cGQFR1ZU2L/KgikqLELVUzplhTU9606	rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606	rigid:LcnDVnfPsJRIl0sJ1qaIWf6qVNM	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O43402	uniprotkb:Q9UHD9	intact:EBI-741841|ensembl:ENSP00000253457|uniprotkb:C9JB21	intact:EBI-947187|uniprotkb:O94798|uniprotkb:Q9H3W6|uniprotkb:Q9HAZ4|uniprotkb:Q5D027|intact:EBI-28967571|ensembl:ENSP00000345195	psi-mi:emc8_human(display_long)|uniprotkb:EMC8(gene name)|psi-mi:EMC8(display_short)|uniprotkb:C16orf2(gene name synonym)|uniprotkb:C16orf4(gene name synonym)|uniprotkb:COX4AL(gene name synonym)|uniprotkb:COX4NB(gene name synonym)|uniprotkb:FAM158B(gene name synonym)|uniprotkb:NOC4(gene name synonym)|uniprotkb:Neighbor of COX4(gene name synonym)|uniprotkb:Protein FAM158B(gene name synonym)	psi-mi:ubql2_human(display_long)|uniprotkb:UBQLN2(gene name)|psi-mi:UBQLN2(display_short)|uniprotkb:PLIC2(gene name synonym)|uniprotkb:HRIHFB2157(orf name)|uniprotkb:N4BP4(gene name synonym)|uniprotkb:Protein linking IAP with cytoskeleton 2(gene name synonym)|uniprotkb:Ubiquitin-like product Chap1/Dsk2(gene name synonym)|uniprotkb:DSK2 homolog(gene name synonym)|uniprotkb:Chap1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770373|imex:IM-28143-52	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006058.1|ensembl:ENSG00000131148(gene)|ensembl:ENST00000253457(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6WW7|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_001135760.1	ensembl:ENSP00000345195|refseq:NP_038472.2|dip:DIP-42116N|ensembl:ENSG00000188021(gene)|ensembl:ENST00000338222(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:1900186"(negative regulation of clathrin-dependent endocytosis)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1904021"(negative regulation of G protein-coupled receptor internalization)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028430|interpro:IPR029071|mint:Q9UHD9|rcsb pdb:1J8C|rcsb pdb:2NBV|rcsb pdb:6MUN|reactome:R-HSA-8856825|genbank_nucl_gi:124056593(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:cGQFR1ZU2L/KgikqLELVUzplhTU9606	rogid:tElcz7gHFkKFVDTz3PXeNcaBP7U9606	rigid:LcnDVnfPsJRIl0sJ1qaIWf6qVNM	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N766	uniprotkb:Q8N4V1	intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62	intact:EBI-6163737|ensembl:ENSP00000306220|ensembl:ENSP00000505226|uniprotkb:B2R625|uniprotkb:B4DIY3|uniprotkb:D3DWG7|uniprotkb:Q5JPP7	psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name)	psi-mi:emc5_human(display_long)|uniprotkb:MMGT1(gene name)|psi-mi:MMGT1(display_short)|uniprotkb:TMEM32(gene name synonym)|uniprotkb:Transmembrane protein 32(gene name synonym)|uniprotkb:EMC5(gene name synonym)|uniprotkb:Membrane magnesium transporter 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770274|imex:IM-28143-38	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1	go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-5223345|ensembl:ENSG00000169446(gene)|ensembl:ENST00000305963(transcript)|ensembl:ENST00000679621(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|refseq:NP_775741.1|refseq:NP_001316929.1|genbank_nucl_gi:74751006(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606	rogid:Kq+VEYt+fwoOsEfcgZ1K1vkFFN49606	rigid:fBYS3CYEF7WxZAjvpN8ZWqIYxG0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N766	uniprotkb:Q9NPA0	intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62	intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5	psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name)	psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770274|imex:IM-28143-38	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1	ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1|genbank_nucl_gi:74752878(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606	rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606	rigid:fBYS3CYEF7WxZAjvpN8ZWqIYxG0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N766	uniprotkb:Q9P0I2	intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62	intact:EBI-1054670|uniprotkb:Q53GH8|uniprotkb:Q6ZMC2|uniprotkb:B2R4Z9|ensembl:ENSP00000245046	psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name)	psi-mi:emc3_human(display_long)|uniprotkb:EMC3(gene name)|psi-mi:EMC3(display_short)|uniprotkb:TMEM111(gene name synonym)|uniprotkb:Transmembrane protein 111(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770274|imex:IM-28143-38	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1	refseq:NP_060917.1|ensembl:ENSG00000125037(gene)|ensembl:ENST00000245046(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008568(Protein of unknown function DUF850, transmembrane eukaryotic)|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-8980692|genbank_nucl_gi:71153383(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606	rogid:VbIl0nFhcDMIPTxmBclaIMtbVU09606	rigid:fBYS3CYEF7WxZAjvpN8ZWqIYxG0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N766	uniprotkb:P27824	intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62	intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000421434|ensembl:ENSP00000421813|ensembl:ENSP00000424063|ensembl:ENSP00000424745|ensembl:ENSP00000491760|ensembl:ENSP00000492372|ensembl:ENSP00000492868|ensembl:ENSP00000505013|ensembl:ENSP00000505202|ensembl:ENSP00000505526|ensembl:ENSP00000505960|ensembl:ENSP00000506003|ensembl:ENSP00000506021|ensembl:ENSP00000506061|ensembl:ENSP00000506078|ensembl:ENSP00000506509|ensembl:ENSP00000506568|ensembl:ENSP00000506583|ensembl:ENSP00000247461|ensembl:ENSP00000391646|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3	psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name)	psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770274|imex:IM-28143-38	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1	refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|go:"GO:0099059"(integral component of presynaptic active zone membrane)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|ensembl:ENST00000452673(transcript)|ensembl:ENST00000502296(transcript)|ensembl:ENST00000504734(transcript)|ensembl:ENST00000509563(transcript)|ensembl:ENST00000513246(transcript)|ensembl:ENST00000638425(transcript)|ensembl:ENST00000638706(transcript)|ensembl:ENST00000639938(transcript)|ensembl:ENST00000680013(transcript)|ensembl:ENST00000680042(transcript)|ensembl:ENST00000680092(transcript)|ensembl:ENST00000680618(transcript)|ensembl:ENST00000681072(transcript)|ensembl:ENST00000681168(transcript)|ensembl:ENST00000681476(transcript)|ensembl:ENST00000681674(transcript)|ensembl:ENST00000681712(transcript)|ensembl:ENST00000681733(transcript)|ensembl:ENST00000681903(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|ensembl:ENST00000247461(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0006457"(protein folding)|go:"GO:0007568"(aging)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|ensembl:ENSG00000127022(gene)|ensembl:ENSG00000283777(gene)|dip:DIP-457N|genbank_nucl_gi:543920(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606	rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606	rigid:fBYS3CYEF7WxZAjvpN8ZWqIYxG0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N766	uniprotkb:Q15006	intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62	intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853	psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name)	psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770274|imex:IM-28143-38	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1	refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|genbank_nucl_gi:3183217(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606	rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606	rigid:fBYS3CYEF7WxZAjvpN8ZWqIYxG0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N766	uniprotkb:O43402	intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62	intact:EBI-741841|ensembl:ENSP00000253457|uniprotkb:C9JB21	psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name)	psi-mi:emc8_human(display_long)|uniprotkb:EMC8(gene name)|psi-mi:EMC8(display_short)|uniprotkb:C16orf2(gene name synonym)|uniprotkb:C16orf4(gene name synonym)|uniprotkb:COX4AL(gene name synonym)|uniprotkb:COX4NB(gene name synonym)|uniprotkb:FAM158B(gene name synonym)|uniprotkb:NOC4(gene name synonym)|uniprotkb:Neighbor of COX4(gene name synonym)|uniprotkb:Protein FAM158B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770274|imex:IM-28143-38	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1	refseq:NP_006058.1|ensembl:ENSG00000131148(gene)|ensembl:ENST00000253457(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6WW7|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_001135760.1|genbank_nucl_gi:18202040(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606	rogid:cGQFR1ZU2L/KgikqLELVUzplhTU9606	rigid:fBYS3CYEF7WxZAjvpN8ZWqIYxG0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N766	uniprotkb:P06733	intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name)	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770274|imex:IM-28143-38	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|genbank_nucl_gi:119339(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	rigid:fBYS3CYEF7WxZAjvpN8ZWqIYxG0	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UBV2	uniprotkb:Q96DZ1	intact:EBI-358766|uniprotkb:Q6UWT6|uniprotkb:Q9P1T9|uniprotkb:Q9UHK7|ensembl:ENSP00000337053	intact:EBI-1023677|uniprotkb:O95901|uniprotkb:Q6UWN7|uniprotkb:Q9NUY7|uniprotkb:Q9UQL4|uniprotkb:B2RDB4|ensembl:ENSP00000185150|uniprotkb:B5MC72	psi-mi:se1l1_human(display_long)|uniprotkb:SEL1L(gene name)|psi-mi:SEL1L(display_short)|uniprotkb:TSA305(gene name synonym)|uniprotkb:UNQ128/PRO1063(orf name)|uniprotkb:Suppressor of lin-12-like protein 1(gene name synonym)	psi-mi:erlec_human(display_long)|uniprotkb:ER lectin(gene name synonym)|uniprotkb:ERLEC1(gene name)|psi-mi:ERLEC1(display_short)|uniprotkb:XTP3TPB(gene name synonym)|uniprotkb:UNQ1878/PRO4321(orf name)|uniprotkb:C2orf30(gene name synonym)|uniprotkb:XTP3-transactivated gene B protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770721|imex:IM-28143-56	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001231913.1|refseq:NP_005056.3|ensembl:ENSG00000071537(gene)|ensembl:ENST00000336735(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0050821"(protein stabilization)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|mint:Q9UBV2|reactome:R-HSA-1912420|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-46259N	refseq:NP_001120870.1|refseq:NP_056516.2|ensembl:ENSG00000068912(gene)|ensembl:ENST00000185150(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR044865|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0036503"(ERAD pathway)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|refseq:NP_001120869.1|genbank_nucl_gi:74731510(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:eufE+8nfcHK8CDl+AQ5G+3NtL+09606	rogid:eBOyI1TfCgExBrXLxSwlUZ05NXs9606	rigid:oksxmz3j0wGYU5lKrDxl+Vezv/4	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UBV2	uniprotkb:Q9Y385	intact:EBI-358766|uniprotkb:Q6UWT6|uniprotkb:Q9P1T9|uniprotkb:Q9UHK7|ensembl:ENSP00000337053	intact:EBI-988826|uniprotkb:Q5W0N4|uniprotkb:Q9BZ32|uniprotkb:Q9NQL3|uniprotkb:Q9NY66|uniprotkb:Q9P011|uniprotkb:Q9P0S0|uniprotkb:Q9UF10|ensembl:ENSP00000451261|uniprotkb:A8K3F9|uniprotkb:Q53F25	psi-mi:se1l1_human(display_long)|uniprotkb:SEL1L(gene name)|psi-mi:SEL1L(display_short)|uniprotkb:TSA305(gene name synonym)|uniprotkb:UNQ128/PRO1063(orf name)|uniprotkb:Suppressor of lin-12-like protein 1(gene name synonym)	psi-mi:ub2j1_human(display_long)|uniprotkb:Non-canonical ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:Yeast ubiquitin-conjugating enzyme UBC6 homolog E(gene name synonym)|uniprotkb:UBE2J1(gene name)|psi-mi:UBE2J1(display_short)|uniprotkb:NCUBE1(gene name synonym)|uniprotkb:CGI-76(orf name)|uniprotkb:HSPC153(orf name)|uniprotkb:HSPC205(orf name)|uniprotkb:E2 ubiquitin-conjugating enzyme J1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770721|imex:IM-28143-56	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001231913.1|refseq:NP_005056.3|ensembl:ENSG00000071537(gene)|ensembl:ENST00000336735(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0050821"(protein stabilization)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|mint:Q9UBV2|reactome:R-HSA-1912420|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-46259N	go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|reactome:R-HSA-983168|ensembl:ENSG00000198833(gene)|ensembl:ENST00000435041(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007286"(spermatid development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:NP_057105.2|dip:DIP-45598N|genbank_nucl_gi:52000881(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:eufE+8nfcHK8CDl+AQ5G+3NtL+09606	rogid:nc3+V3Qxy1ZDhTWgTPLakJukxPM9606	rigid:oksxmz3j0wGYU5lKrDxl+Vezv/4	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UBV2	uniprotkb:Q13438	intact:EBI-358766|uniprotkb:Q6UWT6|uniprotkb:Q9P1T9|uniprotkb:Q9UHK7|ensembl:ENSP00000337053	intact:EBI-725454|intact:EBI-1174342|uniprotkb:A6NDD1|uniprotkb:A6NFR7|uniprotkb:A6NLB2|uniprotkb:A8K5Q9|uniprotkb:B4DPX1|uniprotkb:B4E1I6|uniprotkb:E7ENT8|uniprotkb:F8VUH2|uniprotkb:O00579|uniprotkb:Q6IBL2|uniprotkb:Q8IZ58|uniprotkb:Q9BW99|uniprotkb:B4DE28|ensembl:ENSP00000318165|uniprotkb:E7EW91|uniprotkb:G3XA88	psi-mi:se1l1_human(display_long)|uniprotkb:SEL1L(gene name)|psi-mi:SEL1L(display_short)|uniprotkb:TSA305(gene name synonym)|uniprotkb:UNQ128/PRO1063(orf name)|uniprotkb:Suppressor of lin-12-like protein 1(gene name synonym)	psi-mi:os9_human(display_long)|uniprotkb:OS9(gene name)|psi-mi:OS9(display_short)|uniprotkb:Amplified in osteosarcoma 9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770721|imex:IM-28143-56	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001231913.1|refseq:NP_005056.3|ensembl:ENSG00000071537(gene)|ensembl:ENST00000336735(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0050821"(protein stabilization)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|mint:Q9UBV2|reactome:R-HSA-1912420|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-46259N	refseq:NP_006803.1|refseq:NP_001017956.1|refseq:NP_001017957.1|refseq:NP_001017958.1|refseq:NP_001248349.1|refseq:NP_001248350.1|refseq:NP_001248351.1|refseq:NP_001248352.1|ensembl:ENSG00000135506(gene)|ensembl:ENST00000315970(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0002020"(protease binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006605"(protein targeting)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|interpro:IPR044865|rcsb pdb:3AIH|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-37493N|genbank_nucl_gi:3024310(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:eufE+8nfcHK8CDl+AQ5G+3NtL+09606	rogid:Ntc3geE7th+rBeIp0MxuUuu/28Y9606	rigid:oksxmz3j0wGYU5lKrDxl+Vezv/4	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9GZP9	uniprotkb:P04844	intact:EBI-7962814|uniprotkb:Q9Y3A7|intact:MINT-3065126|ensembl:ENSP00000158771	intact:EBI-719731|uniprotkb:Q5JYR6|uniprotkb:Q9UBE1|uniprotkb:Q6IBA5|uniprotkb:Q96E21|uniprotkb:Q9BUQ3|ensembl:ENSP00000237530	psi-mi:derl2_human(display_long)|uniprotkb:DERL2(gene name)|psi-mi:DERL2(display_short)|uniprotkb:DER2(gene name synonym)|uniprotkb:FLANA(gene name synonym)|uniprotkb:CGI-101(orf name)|uniprotkb:SBBI53(orf name)|uniprotkb:Der1-like protein 2(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 2(gene name synonym)|uniprotkb:F-LAN-1(gene name synonym)|uniprotkb:F-LANa(gene name synonym)	psi-mi:rpn2_human(display_long)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit(gene name synonym)|uniprotkb:Ribophorin-2(gene name synonym)|uniprotkb:Ribophorin II(gene name synonym)|uniprotkb:RIBIIR(gene name synonym)|uniprotkb:RPN2(gene name)|psi-mi:RPN2(display_short)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770670|imex:IM-28143-94	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001291708.1|refseq:NP_057125.2|ensembl:ENSG00000072849(gene)|ensembl:ENST00000158771(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0001967"(suckling behavior)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032	refseq:NP_001129243.1|refseq:NP_002942.2|ensembl:ENSG00000118705(gene)|ensembl:ENST00000237530(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0007568"(aging)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0042493"|go:"GO:0043022"(ribosome binding)|interpro:IPR008814(Ribophorin II)|mint:P04844|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-9694548|refseq:NP_001311234.1|refseq:NP_001311235.1|refseq:NP_001311228.1|refseq:NP_001311230.1|refseq:NP_001311231.1|refseq:NP_001311232.1|refseq:NP_001311233.1|genbank_nucl_gi:9297108(identity)	-	comment:mint|function:"Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate. In contrast to DERL1, it is not involved in the degradation of MHC class I heavy chains following infection by cytomegaloviruses. May play a role in cell proliferation"	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:hoayS/Xn9+pq/C61NYRu/1aOm6s9606	rogid:7bTuuEb3ykWQvkI/5DKpga48s/w9606	rigid:QdSPx1Pc16nJkNVVcMVp9hWQImY	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9GZP9	uniprotkb:Q8N766	intact:EBI-7962814|uniprotkb:Q9Y3A7|intact:MINT-3065126|ensembl:ENSP00000158771	intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62	psi-mi:derl2_human(display_long)|uniprotkb:DERL2(gene name)|psi-mi:DERL2(display_short)|uniprotkb:DER2(gene name synonym)|uniprotkb:FLANA(gene name synonym)|uniprotkb:CGI-101(orf name)|uniprotkb:SBBI53(orf name)|uniprotkb:Der1-like protein 2(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 2(gene name synonym)|uniprotkb:F-LAN-1(gene name synonym)|uniprotkb:F-LANa(gene name synonym)	psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770670|imex:IM-28143-94	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001291708.1|refseq:NP_057125.2|ensembl:ENSG00000072849(gene)|ensembl:ENST00000158771(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0001967"(suckling behavior)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032	go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1|genbank_nucl_gi:74751081(identity)	-	comment:mint|function:"Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate. In contrast to DERL1, it is not involved in the degradation of MHC class I heavy chains following infection by cytomegaloviruses. May play a role in cell proliferation"	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:hoayS/Xn9+pq/C61NYRu/1aOm6s9606	rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606	rigid:QdSPx1Pc16nJkNVVcMVp9hWQImY	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9GZP9	uniprotkb:Q9BSJ8	intact:EBI-7962814|uniprotkb:Q9Y3A7|intact:MINT-3065126|ensembl:ENSP00000158771	intact:EBI-355956|ensembl:ENSP00000377612|uniprotkb:A0FGR7|uniprotkb:A8K2S2|uniprotkb:O94848|uniprotkb:Q6PJN4|uniprotkb:Q9H6J1|uniprotkb:Q9H6W2|uniprotkb:Q9Y416|intact:EBI-4399548	psi-mi:derl2_human(display_long)|uniprotkb:DERL2(gene name)|psi-mi:DERL2(display_short)|uniprotkb:DER2(gene name synonym)|uniprotkb:FLANA(gene name synonym)|uniprotkb:CGI-101(orf name)|uniprotkb:SBBI53(orf name)|uniprotkb:Der1-like protein 2(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 2(gene name synonym)|uniprotkb:F-LAN-1(gene name synonym)|uniprotkb:F-LANa(gene name synonym)	psi-mi:esyt1_human(display_long)|uniprotkb:KIAA0747(gene name synonym)|uniprotkb:MBC2(gene name synonym)|uniprotkb:ESYT1(gene name)|psi-mi:ESYT1(display_short)|uniprotkb:Membrane-bound C2 domain-containing protein(gene name synonym)|uniprotkb:FAM62A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770670|imex:IM-28143-94	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001291708.1|refseq:NP_057125.2|ensembl:ENSG00000072849(gene)|ensembl:ENST00000158771(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0001967"(suckling behavior)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032	interpro:IPR037752|interpro:IPR039010|mint:Q9BSJ8|reactome:R-HSA-1660662|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9035034|interpro:IPR037749|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037733|go:"GO:0005544"(calcium-dependent phospholipid binding)|ensembl:ENSG00000139641(gene)|ensembl:ENST00000394048(transcript)|go:"GO:0005509"(calcium ion binding)|refseq:NP_001171725.1|refseq:NP_056107.1|dip:DIP-57197N|genbank_nucl_gi:74733019(identity)	-	comment:mint|function:"Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate. In contrast to DERL1, it is not involved in the degradation of MHC class I heavy chains following infection by cytomegaloviruses. May play a role in cell proliferation"	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:hoayS/Xn9+pq/C61NYRu/1aOm6s9606	rogid:MYbYK3357LLH0TP1qU7CsvJenGk9606	rigid:QdSPx1Pc16nJkNVVcMVp9hWQImY	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9GZP9	uniprotkb:Q96CS3	intact:EBI-7962814|uniprotkb:Q9Y3A7|intact:MINT-3065126|ensembl:ENSP00000158771	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	psi-mi:derl2_human(display_long)|uniprotkb:DERL2(gene name)|psi-mi:DERL2(display_short)|uniprotkb:DER2(gene name synonym)|uniprotkb:FLANA(gene name synonym)|uniprotkb:CGI-101(orf name)|uniprotkb:SBBI53(orf name)|uniprotkb:Der1-like protein 2(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 2(gene name synonym)|uniprotkb:F-LAN-1(gene name synonym)|uniprotkb:F-LANa(gene name synonym)	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770670|imex:IM-28143-94	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001291708.1|refseq:NP_057125.2|ensembl:ENSG00000072849(gene)|ensembl:ENST00000158771(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0001967"(suckling behavior)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N|genbank_nucl_gi:74731375(identity)	-	comment:mint|function:"Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate. In contrast to DERL1, it is not involved in the degradation of MHC class I heavy chains following infection by cytomegaloviruses. May play a role in cell proliferation"	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:hoayS/Xn9+pq/C61NYRu/1aOm6s9606	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rigid:QdSPx1Pc16nJkNVVcMVp9hWQImY	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9GZP9	uniprotkb:Q9P0I2	intact:EBI-7962814|uniprotkb:Q9Y3A7|intact:MINT-3065126|ensembl:ENSP00000158771	intact:EBI-1054670|uniprotkb:Q53GH8|uniprotkb:Q6ZMC2|uniprotkb:B2R4Z9|ensembl:ENSP00000245046	psi-mi:derl2_human(display_long)|uniprotkb:DERL2(gene name)|psi-mi:DERL2(display_short)|uniprotkb:DER2(gene name synonym)|uniprotkb:FLANA(gene name synonym)|uniprotkb:CGI-101(orf name)|uniprotkb:SBBI53(orf name)|uniprotkb:Der1-like protein 2(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 2(gene name synonym)|uniprotkb:F-LAN-1(gene name synonym)|uniprotkb:F-LANa(gene name synonym)	psi-mi:emc3_human(display_long)|uniprotkb:EMC3(gene name)|psi-mi:EMC3(display_short)|uniprotkb:TMEM111(gene name synonym)|uniprotkb:Transmembrane protein 111(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770670|imex:IM-28143-94	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001291708.1|refseq:NP_057125.2|ensembl:ENSG00000072849(gene)|ensembl:ENST00000158771(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0001967"(suckling behavior)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032	refseq:NP_060917.1|ensembl:ENSG00000125037(gene)|ensembl:ENST00000245046(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008568(Protein of unknown function DUF850, transmembrane eukaryotic)|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-8980692|genbank_nucl_gi:71153383(identity)	-	comment:mint|function:"Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate. In contrast to DERL1, it is not involved in the degradation of MHC class I heavy chains following infection by cytomegaloviruses. May play a role in cell proliferation"	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:hoayS/Xn9+pq/C61NYRu/1aOm6s9606	rogid:VbIl0nFhcDMIPTxmBclaIMtbVU09606	rigid:QdSPx1Pc16nJkNVVcMVp9hWQImY	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9GZP9	uniprotkb:Q9UBV2	intact:EBI-7962814|uniprotkb:Q9Y3A7|intact:MINT-3065126|ensembl:ENSP00000158771	intact:EBI-358766|uniprotkb:Q6UWT6|uniprotkb:Q9P1T9|uniprotkb:Q9UHK7|ensembl:ENSP00000337053	psi-mi:derl2_human(display_long)|uniprotkb:DERL2(gene name)|psi-mi:DERL2(display_short)|uniprotkb:DER2(gene name synonym)|uniprotkb:FLANA(gene name synonym)|uniprotkb:CGI-101(orf name)|uniprotkb:SBBI53(orf name)|uniprotkb:Der1-like protein 2(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 2(gene name synonym)|uniprotkb:F-LAN-1(gene name synonym)|uniprotkb:F-LANa(gene name synonym)	psi-mi:se1l1_human(display_long)|uniprotkb:SEL1L(gene name)|psi-mi:SEL1L(display_short)|uniprotkb:TSA305(gene name synonym)|uniprotkb:UNQ128/PRO1063(orf name)|uniprotkb:Suppressor of lin-12-like protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770670|imex:IM-28143-94	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001291708.1|refseq:NP_057125.2|ensembl:ENSG00000072849(gene)|ensembl:ENST00000158771(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0001967"(suckling behavior)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032	refseq:NP_001231913.1|refseq:NP_005056.3|ensembl:ENSG00000071537(gene)|ensembl:ENST00000336735(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0050821"(protein stabilization)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|mint:Q9UBV2|reactome:R-HSA-1912420|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-46259N|genbank_nucl_gi:62512184(identity)	-	comment:mint|function:"Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate. In contrast to DERL1, it is not involved in the degradation of MHC class I heavy chains following infection by cytomegaloviruses. May play a role in cell proliferation"	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:hoayS/Xn9+pq/C61NYRu/1aOm6s9606	rogid:eufE+8nfcHK8CDl+AQ5G+3NtL+09606	rigid:QdSPx1Pc16nJkNVVcMVp9hWQImY	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9GZP9	uniprotkb:P55072	intact:EBI-7962814|uniprotkb:Q9Y3A7|intact:MINT-3065126|ensembl:ENSP00000158771	intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777	psi-mi:derl2_human(display_long)|uniprotkb:DERL2(gene name)|psi-mi:DERL2(display_short)|uniprotkb:DER2(gene name synonym)|uniprotkb:FLANA(gene name synonym)|uniprotkb:CGI-101(orf name)|uniprotkb:SBBI53(orf name)|uniprotkb:Der1-like protein 2(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 2(gene name synonym)|uniprotkb:F-LAN-1(gene name synonym)|uniprotkb:F-LANa(gene name synonym)	psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770670|imex:IM-28143-94	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001291708.1|refseq:NP_057125.2|ensembl:ENSG00000072849(gene)|ensembl:ENST00000158771(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0001967"(suckling behavior)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032	refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N|genbank_nucl_gi:6094447(identity)	-	comment:mint|function:"Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate. In contrast to DERL1, it is not involved in the degradation of MHC class I heavy chains following infection by cytomegaloviruses. May play a role in cell proliferation"	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:hoayS/Xn9+pq/C61NYRu/1aOm6s9606	rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606	rigid:QdSPx1Pc16nJkNVVcMVp9hWQImY	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9GZP9	uniprotkb:O75915	intact:EBI-7962814|uniprotkb:Q9Y3A7|intact:MINT-3065126|ensembl:ENSP00000158771	intact:EBI-2860752|uniprotkb:B2R6V5|uniprotkb:Q53ES3|uniprotkb:Q5KU08|ensembl:ENSP00000273258	psi-mi:derl2_human(display_long)|uniprotkb:DERL2(gene name)|psi-mi:DERL2(display_short)|uniprotkb:DER2(gene name synonym)|uniprotkb:FLANA(gene name synonym)|uniprotkb:CGI-101(orf name)|uniprotkb:SBBI53(orf name)|uniprotkb:Der1-like protein 2(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 2(gene name synonym)|uniprotkb:F-LAN-1(gene name synonym)|uniprotkb:F-LANa(gene name synonym)	psi-mi:praf3_human(display_long)|uniprotkb:ARL6IP5(gene name)|psi-mi:ARL6IP5(display_short)|uniprotkb:DERP11(gene name synonym)|uniprotkb:JWA(gene name synonym)|uniprotkb:PRA2(gene name synonym)|uniprotkb:PRAF3(gene name synonym)|uniprotkb:ADP-ribosylation factor-like protein 6-interacting protein 5(gene name synonym)|uniprotkb:Cytoskeleton-related vitamin A-responsive protein(gene name synonym)|uniprotkb:Dermal papilla-derived protein 11(gene name synonym)|uniprotkb:GTRAP3-18(gene name synonym)|uniprotkb:Glutamate transporter EAAC1-interacting protein(gene name synonym)|uniprotkb:JM5(gene name synonym)|uniprotkb:Prenylated Rab acceptor protein 2(gene name synonym)|uniprotkb:Protein JWa(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM27(gene name synonym)|uniprotkb:HSPC127(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770670|imex:IM-28143-94	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001291708.1|refseq:NP_057125.2|ensembl:ENSG00000072849(gene)|ensembl:ENST00000158771(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0001967"(suckling behavior)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032	refseq:NP_006398.1|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051051"(negative regulation of transport)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098712"(L-glutamate import across plasma membrane)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:O75915|reactome:R-HSA-210500|ensembl:ENSG00000144746(gene)|ensembl:ENST00000273258(transcript)|go:"GO:0002037"(negative regulation of L-glutamate import across plasma membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0007611"(learning or memory)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0015031"(protein transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036475"(neuron death in response to oxidative stress)|go:"GO:0043065"(positive regulation of apoptotic process)|genbank_nucl_gi:57012996(identity)	-	comment:mint|function:"Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate. In contrast to DERL1, it is not involved in the degradation of MHC class I heavy chains following infection by cytomegaloviruses. May play a role in cell proliferation"	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:hoayS/Xn9+pq/C61NYRu/1aOm6s9606	rogid:TG2yH1gqzVhFgxBtuZqsE1dLAvQ9606	rigid:QdSPx1Pc16nJkNVVcMVp9hWQImY	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9GZP9	uniprotkb:Q9BUN8	intact:EBI-7962814|uniprotkb:Q9Y3A7|intact:MINT-3065126|ensembl:ENSP00000158771	intact:EBI-398977|uniprotkb:B3KW41|uniprotkb:E9PH19|ensembl:ENSP00000259512	psi-mi:derl2_human(display_long)|uniprotkb:DERL2(gene name)|psi-mi:DERL2(display_short)|uniprotkb:DER2(gene name synonym)|uniprotkb:FLANA(gene name synonym)|uniprotkb:CGI-101(orf name)|uniprotkb:SBBI53(orf name)|uniprotkb:Der1-like protein 2(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 2(gene name synonym)|uniprotkb:F-LAN-1(gene name synonym)|uniprotkb:F-LANa(gene name synonym)	psi-mi:derl1_human(display_long)|uniprotkb:DERL1(gene name)|psi-mi:DERL1(display_short)|uniprotkb:UNQ243/PRO276(orf name)|uniprotkb:Der1-like protein 1(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:DER1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770670|imex:IM-28143-94	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001291708.1|refseq:NP_057125.2|ensembl:ENSG00000072849(gene)|ensembl:ENST00000158771(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0001967"(suckling behavior)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032	refseq:NP_001128143.1|refseq:NP_077271.1|ensembl:ENSG00000136986(gene)|ensembl:ENST00000259512(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002020"(protease binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0036502"(Derlin-1-VIMP complex)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|rcsb pdb:5GLF|rcsb pdb:7CZB|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5678895|reactome:R-HSA-8866654|genbank_nucl_gi:50400630(identity)	-	comment:mint|function:"Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate. In contrast to DERL1, it is not involved in the degradation of MHC class I heavy chains following infection by cytomegaloviruses. May play a role in cell proliferation"	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:hoayS/Xn9+pq/C61NYRu/1aOm6s9606	rogid:M35Ah+CuYuV7RP1edsda6vU7Bgo9606	rigid:QdSPx1Pc16nJkNVVcMVp9hWQImY	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9GZP9	uniprotkb:Q9UKV5	intact:EBI-7962814|uniprotkb:Q9Y3A7|intact:MINT-3065126|ensembl:ENSP00000158771	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	psi-mi:derl2_human(display_long)|uniprotkb:DERL2(gene name)|psi-mi:DERL2(display_short)|uniprotkb:DER2(gene name synonym)|uniprotkb:FLANA(gene name synonym)|uniprotkb:CGI-101(orf name)|uniprotkb:SBBI53(orf name)|uniprotkb:Der1-like protein 2(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 2(gene name synonym)|uniprotkb:F-LAN-1(gene name synonym)|uniprotkb:F-LANa(gene name synonym)	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770670|imex:IM-28143-94	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001291708.1|refseq:NP_057125.2|ensembl:ENSG00000072849(gene)|ensembl:ENST00000158771(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0001967"(suckling behavior)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N|genbank_nucl_gi:34922250(identity)	-	comment:mint|function:"Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate. In contrast to DERL1, it is not involved in the degradation of MHC class I heavy chains following infection by cytomegaloviruses. May play a role in cell proliferation"	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:hoayS/Xn9+pq/C61NYRu/1aOm6s9606	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rigid:QdSPx1Pc16nJkNVVcMVp9hWQImY	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9GZP9	uniprotkb:Q9BQE4	intact:EBI-7962814|uniprotkb:Q9Y3A7|intact:MINT-3065126|ensembl:ENSP00000158771	intact:EBI-398970|uniprotkb:Q3B771|uniprotkb:Q9P0I6|ensembl:ENSP00000381282|ensembl:ENSP00000433541	psi-mi:derl2_human(display_long)|uniprotkb:DERL2(gene name)|psi-mi:DERL2(display_short)|uniprotkb:DER2(gene name synonym)|uniprotkb:FLANA(gene name synonym)|uniprotkb:CGI-101(orf name)|uniprotkb:SBBI53(orf name)|uniprotkb:Der1-like protein 2(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 2(gene name synonym)|uniprotkb:F-LAN-1(gene name synonym)|uniprotkb:F-LANa(gene name synonym)	psi-mi:sels_human(display_long)|uniprotkb:SELENOS(gene name)|psi-mi:SELENOS(display_short)|uniprotkb:SELS(gene name synonym)|uniprotkb:VCP-interacting membrane protein(gene name synonym)|uniprotkb:VIMP(gene name synonym)|uniprotkb:AD-015(orf name)|uniprotkb:SBBI8(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770670|imex:IM-28143-94	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001291708.1|refseq:NP_057125.2|ensembl:ENSG00000072849(gene)|ensembl:ENST00000158771(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0001967"(suckling behavior)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032	refseq:NP_060915.2|refseq:NP_982298.2|ensembl:ENSG00000131871(gene)|ensembl:ENST00000398226(transcript)|ensembl:ENST00000526049(transcript)|go:"GO:0002865"(negative regulation of acute inflammatory response to antigenic stimulus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006983"(ER overload response)|go:"GO:0009749"(response to glucose)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036502"(Derlin-1-VIMP complex)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051117"(ATPase binding)|go:"GO:0051775"(response to redox state)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080164"(regulation of nitric oxide metabolic process)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR009703(Selenoprotein S)|rcsb pdb:2Q2F|rcsb pdb:5KIU|rcsb pdb:5KIY|rcsb pdb:6DO4|reactome:R-HSA-8866654|go:"GO:0051771"(negative regulation of nitric-oxide synthase biosynthetic process)|genbank_nucl_gi:33285002(identity)	-	comment:mint|function:"Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate. In contrast to DERL1, it is not involved in the degradation of MHC class I heavy chains following infection by cytomegaloviruses. May play a role in cell proliferation"	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:hoayS/Xn9+pq/C61NYRu/1aOm6s9606	rogid:bg+Gf++/TqIgpUErI5PgcLomcCQ9606	rigid:QdSPx1Pc16nJkNVVcMVp9hWQImY	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9GZP9	uniprotkb:Q15006	intact:EBI-7962814|uniprotkb:Q9Y3A7|intact:MINT-3065126|ensembl:ENSP00000158771	intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853	psi-mi:derl2_human(display_long)|uniprotkb:DERL2(gene name)|psi-mi:DERL2(display_short)|uniprotkb:DER2(gene name synonym)|uniprotkb:FLANA(gene name synonym)|uniprotkb:CGI-101(orf name)|uniprotkb:SBBI53(orf name)|uniprotkb:Der1-like protein 2(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 2(gene name synonym)|uniprotkb:F-LAN-1(gene name synonym)|uniprotkb:F-LANa(gene name synonym)	psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770670|imex:IM-28143-94	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001291708.1|refseq:NP_057125.2|ensembl:ENSG00000072849(gene)|ensembl:ENST00000158771(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0001967"(suckling behavior)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032	refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|genbank_nucl_gi:3183217(identity)	-	comment:mint|function:"Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate. In contrast to DERL1, it is not involved in the degradation of MHC class I heavy chains following infection by cytomegaloviruses. May play a role in cell proliferation"	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:hoayS/Xn9+pq/C61NYRu/1aOm6s9606	rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606	rigid:QdSPx1Pc16nJkNVVcMVp9hWQImY	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9GZP9	uniprotkb:Q92575	intact:EBI-7962814|uniprotkb:Q9Y3A7|intact:MINT-3065126|ensembl:ENSP00000158771	intact:EBI-723441|uniprotkb:Q4ZG56|uniprotkb:Q8IYM5|intact:EBI-28978946|ensembl:ENSP00000272638|uniprotkb:A8K9W4	psi-mi:derl2_human(display_long)|uniprotkb:DERL2(gene name)|psi-mi:DERL2(display_short)|uniprotkb:DER2(gene name synonym)|uniprotkb:FLANA(gene name synonym)|uniprotkb:CGI-101(orf name)|uniprotkb:SBBI53(orf name)|uniprotkb:Der1-like protein 2(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 2(gene name synonym)|uniprotkb:F-LAN-1(gene name synonym)|uniprotkb:F-LANa(gene name synonym)	psi-mi:ubxn4_human(display_long)|uniprotkb:Erasin(gene name synonym)|uniprotkb:UBXN4(gene name)|psi-mi:UBXN4(display_short)|uniprotkb:KIAA0242(gene name synonym)|uniprotkb:UBXDC1(gene name synonym)|uniprotkb:UBXD2(gene name synonym)|uniprotkb:UBX domain-containing protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770670|imex:IM-28143-94	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001291708.1|refseq:NP_057125.2|ensembl:ENSG00000072849(gene)|ensembl:ENST00000158771(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0001967"(suckling behavior)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032	refseq:NP_055422.1|ensembl:ENSG00000144224(gene)|ensembl:ENST00000272638(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|interpro:IPR001012(UBX)|interpro:IPR029071|interpro:IPR036249|rcsb pdb:2KXJ|ensembl:ENSP00000272638|genbank_nucl_gi:30913402(identity)	-	comment:mint|function:"Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate. In contrast to DERL1, it is not involved in the degradation of MHC class I heavy chains following infection by cytomegaloviruses. May play a role in cell proliferation"	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:hoayS/Xn9+pq/C61NYRu/1aOm6s9606	rogid:rWCmtHlje9EFw7YVQQNJBBH4bLE9606	rigid:QdSPx1Pc16nJkNVVcMVp9hWQImY	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9GZP9	uniprotkb:P16435	intact:EBI-7962814|uniprotkb:Q9Y3A7|intact:MINT-3065126|ensembl:ENSP00000158771	intact:EBI-726554|uniprotkb:Q9UDT3|uniprotkb:Q16455|uniprotkb:Q8N181|uniprotkb:Q9H3M8|uniprotkb:Q197M5|ensembl:ENSP00000378355|ensembl:ENSP00000389409|ensembl:ENSP00000389719|ensembl:ENSP00000390540|ensembl:ENSP00000395813|ensembl:ENSP00000399327|ensembl:ENSP00000399556|ensembl:ENSP00000404731|ensembl:ENSP00000409238|ensembl:ENSP00000414263|ensembl:ENSP00000419970	psi-mi:derl2_human(display_long)|uniprotkb:DERL2(gene name)|psi-mi:DERL2(display_short)|uniprotkb:DER2(gene name synonym)|uniprotkb:FLANA(gene name synonym)|uniprotkb:CGI-101(orf name)|uniprotkb:SBBI53(orf name)|uniprotkb:Der1-like protein 2(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 2(gene name synonym)|uniprotkb:F-LAN-1(gene name synonym)|uniprotkb:F-LANa(gene name synonym)	psi-mi:ncpr_human(display_long)|uniprotkb:POR(gene name)|psi-mi:POR(display_short)|uniprotkb:CYPOR(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770670|imex:IM-28143-94	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001291708.1|refseq:NP_057125.2|ensembl:ENSG00000072849(gene)|ensembl:ENST00000158771(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0001967"(suckling behavior)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032	refseq:NP_000932.3|ensembl:ENSG00000127948(gene)|ensembl:ENST00000394893(transcript)|ensembl:ENST00000412064(transcript)|ensembl:ENST00000412521(transcript)|ensembl:ENST00000414186(transcript)|ensembl:ENST00000418341(transcript)|ensembl:ENST00000432753(transcript)|ensembl:ENST00000439963(transcript)|ensembl:ENST00000449920(transcript)|ensembl:ENST00000453773(transcript)|ensembl:ENST00000454934(transcript)|ensembl:ENST00000461988(transcript)|go:"GO:0003420"(regulation of growth plate cartilage chondrocyte proliferation)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008941"(nitric oxide dioxygenase activity)|go:"GO:0009055"(electron transfer activity)|go:"GO:0009437"(carnitine metabolic process)|go:"GO:0009725"(response to hormone)|go:"GO:0009812"(flavonoid metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0016787"(hydrolase activity)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0019899"(enzyme binding)|go:"GO:0022900"(electron transport chain)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032770"(positive regulation of monooxygenase activity)|go:"GO:0042493"|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043602"(nitrate catabolic process)|go:"GO:0045542"(positive regulation of cholesterol biosynthetic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046210"(nitric oxide catabolic process)|go:"GO:0047726"(iron-cytochrome-c reductase activity)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:0060192"(negative regulation of lipase activity)|go:"GO:0070988"(demethylation)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090031"(positive regulation of steroid hormone biosynthetic process)|go:"GO:0090346"(cellular organofluorine metabolic process)|interpro:IPR001094(Flavodoxin-like)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023173|interpro:IPR023208|interpro:IPR029039|interpro:IPR039261|rcsb pdb:1B1C|rcsb pdb:3FJO|rcsb pdb:3QE2|rcsb pdb:3QFC|rcsb pdb:3QFR|rcsb pdb:3QFS|rcsb pdb:3QFT|rcsb pdb:5EMN|rcsb pdb:5FA6|reactome:R-HSA-211897|dip:DIP-29682N|genbank_nucl_gi:2851393(identity)	-	comment:mint|function:"Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate. In contrast to DERL1, it is not involved in the degradation of MHC class I heavy chains following infection by cytomegaloviruses. May play a role in cell proliferation"	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:hoayS/Xn9+pq/C61NYRu/1aOm6s9606	rogid:Tgl0hfwgwo16Yw+kH4JIdIaRPpM9606	rigid:QdSPx1Pc16nJkNVVcMVp9hWQImY	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9GZP9	uniprotkb:P46977	intact:EBI-7962814|uniprotkb:Q9Y3A7|intact:MINT-3065126|ensembl:ENSP00000158771	intact:EBI-719212|uniprotkb:Q86XU9|uniprotkb:Q8TE35|uniprotkb:Q8WUB4|ensembl:ENSP00000376472|ensembl:ENSP00000436962|ensembl:ENSP00000497336|uniprotkb:B4DJ24|uniprotkb:E9PNQ1	psi-mi:derl2_human(display_long)|uniprotkb:DERL2(gene name)|psi-mi:DERL2(display_short)|uniprotkb:DER2(gene name synonym)|uniprotkb:FLANA(gene name synonym)|uniprotkb:CGI-101(orf name)|uniprotkb:SBBI53(orf name)|uniprotkb:Der1-like protein 2(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 2(gene name synonym)|uniprotkb:F-LAN-1(gene name synonym)|uniprotkb:F-LANa(gene name synonym)	psi-mi:stt3a_human(display_long)|uniprotkb:TMC(gene name synonym)|uniprotkb:B5(gene name synonym)|uniprotkb:Integral membrane protein 1(gene name synonym)|uniprotkb:Transmembrane protein TMC(gene name synonym)|uniprotkb:STT3A(gene name)|psi-mi:STT3A(display_short)|uniprotkb:ITM1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770670|imex:IM-28143-94	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001291708.1|refseq:NP_057125.2|ensembl:ENSG00000072849(gene)|ensembl:ENST00000158771(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0001967"(suckling behavior)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032	refseq:NP_689926.1|ensembl:ENSG00000134910(gene)|ensembl:ENST00000392708(transcript)|ensembl:ENST00000529196(transcript)|ensembl:ENST00000649491(transcript)|go:"GO:0004579"(dolichyl-diphosphooligosaccharide-protein glycotransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0035000"(oligosaccharyltransferase III complex)|go:"GO:0043686"(co-translational protein modification)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0046872"(metal ion binding)|interpro:IPR003674(Oligosaccharyl transferase, STT3 subunit)|mint:P46977|rcsb pdb:6S7O|reactome:R-HSA-446203|reactome:R-HSA-9694548|refseq:XP_011541109.1|refseq:NP_001265432.1|refseq:NP_001265433.1|genbank_nucl_gi:22749415(identity)	-	comment:mint|function:"Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate. In contrast to DERL1, it is not involved in the degradation of MHC class I heavy chains following infection by cytomegaloviruses. May play a role in cell proliferation"	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:hoayS/Xn9+pq/C61NYRu/1aOm6s9606	rogid:DS4CIkIc7Ib6qxOFDBQNVRmmytU9606	rigid:QdSPx1Pc16nJkNVVcMVp9hWQImY	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BUN8	uniprotkb:Q8N766	intact:EBI-398977|uniprotkb:B3KW41|uniprotkb:E9PH19|ensembl:ENSP00000259512	intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62	psi-mi:derl1_human(display_long)|uniprotkb:DERL1(gene name)|psi-mi:DERL1(display_short)|uniprotkb:UNQ243/PRO276(orf name)|uniprotkb:Der1-like protein 1(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:DER1(gene name synonym)	psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770511|imex:IM-28143-92	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128143.1|refseq:NP_077271.1|ensembl:ENSG00000136986(gene)|ensembl:ENST00000259512(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002020"(protease binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0036502"(Derlin-1-VIMP complex)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|rcsb pdb:5GLF|rcsb pdb:7CZB|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5678895|reactome:R-HSA-8866654	go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1|genbank_nucl_gi:74751081(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:M35Ah+CuYuV7RP1edsda6vU7Bgo9606	rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606	rigid:m2e0zgR13NeDG4MUhAuIcF+LZLc	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BUN8	uniprotkb:Q9BSJ8	intact:EBI-398977|uniprotkb:B3KW41|uniprotkb:E9PH19|ensembl:ENSP00000259512	intact:EBI-355956|ensembl:ENSP00000377612|uniprotkb:A0FGR7|uniprotkb:A8K2S2|uniprotkb:O94848|uniprotkb:Q6PJN4|uniprotkb:Q9H6J1|uniprotkb:Q9H6W2|uniprotkb:Q9Y416|intact:EBI-4399548	psi-mi:derl1_human(display_long)|uniprotkb:DERL1(gene name)|psi-mi:DERL1(display_short)|uniprotkb:UNQ243/PRO276(orf name)|uniprotkb:Der1-like protein 1(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:DER1(gene name synonym)	psi-mi:esyt1_human(display_long)|uniprotkb:KIAA0747(gene name synonym)|uniprotkb:MBC2(gene name synonym)|uniprotkb:ESYT1(gene name)|psi-mi:ESYT1(display_short)|uniprotkb:Membrane-bound C2 domain-containing protein(gene name synonym)|uniprotkb:FAM62A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770511|imex:IM-28143-92	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128143.1|refseq:NP_077271.1|ensembl:ENSG00000136986(gene)|ensembl:ENST00000259512(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002020"(protease binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0036502"(Derlin-1-VIMP complex)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|rcsb pdb:5GLF|rcsb pdb:7CZB|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5678895|reactome:R-HSA-8866654	interpro:IPR037752|interpro:IPR039010|mint:Q9BSJ8|reactome:R-HSA-1660662|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9035034|interpro:IPR037749|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037733|go:"GO:0005544"(calcium-dependent phospholipid binding)|ensembl:ENSG00000139641(gene)|ensembl:ENST00000394048(transcript)|go:"GO:0005509"(calcium ion binding)|refseq:NP_001171725.1|refseq:NP_056107.1|dip:DIP-57197N|genbank_nucl_gi:74733019(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:M35Ah+CuYuV7RP1edsda6vU7Bgo9606	rogid:MYbYK3357LLH0TP1qU7CsvJenGk9606	rigid:m2e0zgR13NeDG4MUhAuIcF+LZLc	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BUN8	uniprotkb:Q96CS3	intact:EBI-398977|uniprotkb:B3KW41|uniprotkb:E9PH19|ensembl:ENSP00000259512	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	psi-mi:derl1_human(display_long)|uniprotkb:DERL1(gene name)|psi-mi:DERL1(display_short)|uniprotkb:UNQ243/PRO276(orf name)|uniprotkb:Der1-like protein 1(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:DER1(gene name synonym)	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770511|imex:IM-28143-92	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128143.1|refseq:NP_077271.1|ensembl:ENSG00000136986(gene)|ensembl:ENST00000259512(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002020"(protease binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0036502"(Derlin-1-VIMP complex)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|rcsb pdb:5GLF|rcsb pdb:7CZB|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5678895|reactome:R-HSA-8866654	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N|genbank_nucl_gi:74731375(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:M35Ah+CuYuV7RP1edsda6vU7Bgo9606	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rigid:m2e0zgR13NeDG4MUhAuIcF+LZLc	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BUN8	uniprotkb:O15173	intact:EBI-398977|uniprotkb:B3KW41|uniprotkb:E9PH19|ensembl:ENSP00000259512	intact:EBI-1050125|uniprotkb:Q569H1|ensembl:ENSP00000296425|ensembl:ENSP00000429301	psi-mi:derl1_human(display_long)|uniprotkb:DERL1(gene name)|psi-mi:DERL1(display_short)|uniprotkb:UNQ243/PRO276(orf name)|uniprotkb:Der1-like protein 1(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:DER1(gene name synonym)	psi-mi:pgrc2_human(display_long)|uniprotkb:Progesterone membrane-binding protein(gene name synonym)|uniprotkb:Steroid receptor protein DG6(gene name synonym)|uniprotkb:PGRMC2(gene name)|psi-mi:PGRMC2(display_short)|uniprotkb:DG6(gene name synonym)|uniprotkb:PMBP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770511|imex:IM-28143-92	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128143.1|refseq:NP_077271.1|ensembl:ENSG00000136986(gene)|ensembl:ENST00000259512(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002020"(protease binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0036502"(Derlin-1-VIMP complex)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|rcsb pdb:5GLF|rcsb pdb:7CZB|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5678895|reactome:R-HSA-8866654	refseq:NP_006311.2|ensembl:ENSG00000164040(gene)|ensembl:ENST00000296425(transcript)|ensembl:ENST00000520121(transcript)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0012505"(endomembrane system)|go:"GO:0015232"(heme transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0060612"(adipose tissue development)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|mint:O15173|reactome:R-HSA-8980692|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|genbank_nucl_gi:6647832(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:M35Ah+CuYuV7RP1edsda6vU7Bgo9606	rogid:y8PU98eUcxnJLxobBcFL40xaprw9606	rigid:m2e0zgR13NeDG4MUhAuIcF+LZLc	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BUN8	uniprotkb:P55072	intact:EBI-398977|uniprotkb:B3KW41|uniprotkb:E9PH19|ensembl:ENSP00000259512	intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777	psi-mi:derl1_human(display_long)|uniprotkb:DERL1(gene name)|psi-mi:DERL1(display_short)|uniprotkb:UNQ243/PRO276(orf name)|uniprotkb:Der1-like protein 1(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:DER1(gene name synonym)	psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770511|imex:IM-28143-92	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128143.1|refseq:NP_077271.1|ensembl:ENSG00000136986(gene)|ensembl:ENST00000259512(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002020"(protease binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0036502"(Derlin-1-VIMP complex)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|rcsb pdb:5GLF|rcsb pdb:7CZB|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5678895|reactome:R-HSA-8866654	refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N|genbank_nucl_gi:6094447(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:M35Ah+CuYuV7RP1edsda6vU7Bgo9606	rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606	rigid:m2e0zgR13NeDG4MUhAuIcF+LZLc	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BUN8	uniprotkb:O75915	intact:EBI-398977|uniprotkb:B3KW41|uniprotkb:E9PH19|ensembl:ENSP00000259512	intact:EBI-2860752|uniprotkb:B2R6V5|uniprotkb:Q53ES3|uniprotkb:Q5KU08|ensembl:ENSP00000273258	psi-mi:derl1_human(display_long)|uniprotkb:DERL1(gene name)|psi-mi:DERL1(display_short)|uniprotkb:UNQ243/PRO276(orf name)|uniprotkb:Der1-like protein 1(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:DER1(gene name synonym)	psi-mi:praf3_human(display_long)|uniprotkb:ARL6IP5(gene name)|psi-mi:ARL6IP5(display_short)|uniprotkb:DERP11(gene name synonym)|uniprotkb:JWA(gene name synonym)|uniprotkb:PRA2(gene name synonym)|uniprotkb:PRAF3(gene name synonym)|uniprotkb:ADP-ribosylation factor-like protein 6-interacting protein 5(gene name synonym)|uniprotkb:Cytoskeleton-related vitamin A-responsive protein(gene name synonym)|uniprotkb:Dermal papilla-derived protein 11(gene name synonym)|uniprotkb:GTRAP3-18(gene name synonym)|uniprotkb:Glutamate transporter EAAC1-interacting protein(gene name synonym)|uniprotkb:JM5(gene name synonym)|uniprotkb:Prenylated Rab acceptor protein 2(gene name synonym)|uniprotkb:Protein JWa(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM27(gene name synonym)|uniprotkb:HSPC127(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770511|imex:IM-28143-92	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128143.1|refseq:NP_077271.1|ensembl:ENSG00000136986(gene)|ensembl:ENST00000259512(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002020"(protease binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0036502"(Derlin-1-VIMP complex)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|rcsb pdb:5GLF|rcsb pdb:7CZB|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5678895|reactome:R-HSA-8866654	refseq:NP_006398.1|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051051"(negative regulation of transport)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098712"(L-glutamate import across plasma membrane)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:O75915|reactome:R-HSA-210500|ensembl:ENSG00000144746(gene)|ensembl:ENST00000273258(transcript)|go:"GO:0002037"(negative regulation of L-glutamate import across plasma membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0007611"(learning or memory)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0015031"(protein transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036475"(neuron death in response to oxidative stress)|go:"GO:0043065"(positive regulation of apoptotic process)|genbank_nucl_gi:57012996(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:M35Ah+CuYuV7RP1edsda6vU7Bgo9606	rogid:TG2yH1gqzVhFgxBtuZqsE1dLAvQ9606	rigid:m2e0zgR13NeDG4MUhAuIcF+LZLc	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BUN8	uniprotkb:O75396	intact:EBI-398977|uniprotkb:B3KW41|uniprotkb:E9PH19|ensembl:ENSP00000259512	intact:EBI-1058865|ensembl:ENSP00000463393|uniprotkb:A8K1G0	psi-mi:derl1_human(display_long)|uniprotkb:DERL1(gene name)|psi-mi:DERL1(display_short)|uniprotkb:UNQ243/PRO276(orf name)|uniprotkb:Der1-like protein 1(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:DER1(gene name synonym)	psi-mi:sc22b_human(display_long)|uniprotkb:SEC22B(gene name)|psi-mi:SEC22B(display_short)|uniprotkb:SEC22L1(gene name synonym)|uniprotkb:SEC22 vesicle-trafficking protein homolog B(gene name synonym)|uniprotkb:SEC22 vesicle-trafficking protein-like 1(gene name synonym)|uniprotkb:ER-Golgi SNARE of 24 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770511|imex:IM-28143-92	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128143.1|refseq:NP_077271.1|ensembl:ENSG00000136986(gene)|ensembl:ENST00000259512(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002020"(protease binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0036502"(Derlin-1-VIMP complex)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|rcsb pdb:5GLF|rcsb pdb:7CZB|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5678895|reactome:R-HSA-8866654	ensembl:ENSG00000265808(gene)|ensembl:ENST00000578049(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042470"(melanosome)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR001388(Synaptobrevin)|interpro:IPR010908(Longin)|interpro:IPR011012(Longin-like)|interpro:IPR042855|interpro:IPR044565|mint:O75396|rcsb pdb:2NUP|rcsb pdb:2NUT|rcsb pdb:3EGD|rcsb pdb:3EGX|refseq:NP_004883.3|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6811434|reactome:R-HSA-1236974|dip:DIP-50458N|genbank_nucl_gi:46397702(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:M35Ah+CuYuV7RP1edsda6vU7Bgo9606	rogid:DRKtD169T9eYZ2kFufLapidvcKs9606	rigid:m2e0zgR13NeDG4MUhAuIcF+LZLc	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BUN8	uniprotkb:Q9NQC3	intact:EBI-398977|uniprotkb:B3KW41|uniprotkb:E9PH19|ensembl:ENSP00000259512	intact:EBI-715945|intact:EBI-1753019|uniprotkb:O94962|uniprotkb:Q9BXG5|uniprotkb:Q9H212|uniprotkb:Q9H3I3|uniprotkb:Q9UQ42|uniprotkb:Q9Y293|uniprotkb:Q9Y2Y7|uniprotkb:Q9Y5U6|intact:EBI-1958210|intact:EBI-1056082|uniprotkb:Q7L7Q8|uniprotkb:Q96B16|intact:EBI-28967519|ensembl:ENSP00000337838|uniprotkb:Q7L7Q5|uniprotkb:Q7L7Q6|uniprotkb:Q8IUA4	psi-mi:derl1_human(display_long)|uniprotkb:DERL1(gene name)|psi-mi:DERL1(display_short)|uniprotkb:UNQ243/PRO276(orf name)|uniprotkb:Der1-like protein 1(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:DER1(gene name synonym)	psi-mi:rtn4_human(display_long)|uniprotkb:Neurite outgrowth inhibitor(gene name synonym)|uniprotkb:Foocen(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:Neuroendocrine-specific protein C homolog(gene name synonym)|uniprotkb:RTN-x(gene name synonym)|uniprotkb:Reticulon-5(gene name synonym)|uniprotkb:RTN4(gene name)|psi-mi:RTN4(display_short)|uniprotkb:KIAA0886(gene name synonym)|uniprotkb:NOGO(gene name synonym)|uniprotkb:My043(orf name)|uniprotkb:SP1507(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770511|imex:IM-28143-92	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128143.1|refseq:NP_077271.1|ensembl:ENSG00000136986(gene)|ensembl:ENST00000259512(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002020"(protease binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0036502"(Derlin-1-VIMP complex)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|rcsb pdb:5GLF|rcsb pdb:7CZB|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5678895|reactome:R-HSA-8866654	ensembl:ENST00000317610|ensembl:ENSP00000322147|ensembl:ENSP00000337838|ensembl:ENST00000357376|ensembl:ENSP00000349944|ensembl:ENST00000357732|ensembl:ENSP00000350365|ensembl:ENST00000394609|ensembl:ENSP00000378107|ensembl:ENST00000394611|ensembl:ENSP00000378109|ensembl:ENST00000404909|ensembl:ENSP00000385650|ensembl:ENST00000405240|ensembl:ENSP00000384471|refseq:NP_008939.1|refseq:NP_065393.1|refseq:NP_722550.1|refseq:NP_997403.1|refseq:NP_997404.1|ensembl:ENSG00000115310(gene)|ensembl:ENST00000337526(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0014069"(postsynaptic density)|go:"GO:0021801"(cerebral cortex radial glia-guided migration)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0035441"(cell migration involved in vasculogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0042995"(cell projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:0098826"(endoplasmic reticulum tubular network membrane)|go:"GO:0120078"(cell adhesion involved in sprouting angiogenesis)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902624"(positive regulation of neutrophil migration)|go:"GO:1905523"(positive regulation of macrophage migration)|go:"GO:1905552"(positive regulation of protein localization to endoplasmic reticulum)|go:"GO:1905580"(positive regulation of ERBB3 signaling pathway)|go:"GO:1905653"(positive regulation of artery morphogenesis)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|go:"GO:2000172"(regulation of branching morphogenesis of a nerve)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001213"(negative regulation of vasculogenesis)|interpro:IPR003388(Reticulon)|mint:Q9NQC3|rcsb pdb:2G31|rcsb pdb:2JV5|reactome:R-HSA-193634|refseq:XP_005264491.1|refseq:NP_001308788.1|refseq:NP_001308789.1|refseq:NP_001308790.1|refseq:NP_001308791.1|refseq:NP_001308792.1|refseq:NP_001308833.1|refseq:XP_016860007.1|refseq:XP_016860008.1|dip:DIP-42003N|genbank_nucl_gi:24431933(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:M35Ah+CuYuV7RP1edsda6vU7Bgo9606	rogid:uhivTNOPdC7+q81CliY0Ozu0EwA9606	rigid:m2e0zgR13NeDG4MUhAuIcF+LZLc	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BUN8	uniprotkb:Q5BJH7	intact:EBI-398977|uniprotkb:B3KW41|uniprotkb:E9PH19|ensembl:ENSP00000259512	intact:EBI-11288011|uniprotkb:H7BXS8|uniprotkb:Q5JPC2|uniprotkb:Q8WY70|uniprotkb:Q96C02|uniprotkb:Q96IC4|ensembl:ENSP00000343435	psi-mi:derl1_human(display_long)|uniprotkb:DERL1(gene name)|psi-mi:DERL1(display_short)|uniprotkb:UNQ243/PRO276(orf name)|uniprotkb:Der1-like protein 1(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:DER1(gene name synonym)	psi-mi:yif1b_human(display_long)|uniprotkb:YIF1B(gene name)|psi-mi:YIF1B(display_short)|uniprotkb:YIP1-interacting factor homolog B(gene name synonym)|uniprotkb:PP4519(orf name)|uniprotkb:UNQ3073/PRO9905(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770511|imex:IM-28143-92	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128143.1|refseq:NP_077271.1|ensembl:ENSG00000136986(gene)|ensembl:ENST00000259512(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002020"(protease binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0036502"(Derlin-1-VIMP complex)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|rcsb pdb:5GLF|rcsb pdb:7CZB|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5678895|reactome:R-HSA-8866654	refseq:NP_001034761.1|refseq:NP_001034762.1|refseq:NP_001138934.1|refseq:NP_001138935.1|refseq:XP_005259442.1|refseq:XP_016882938.1|ensembl:ENSG00000167645(gene)|ensembl:ENST00000339413(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|interpro:IPR005578(Hrf1)|mint:Q5BJH7|genbank_nucl_gi:24308364(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:M35Ah+CuYuV7RP1edsda6vU7Bgo9606	rogid:Vq4GGKQqOKq1sydz+NMnUNcriWQ9606	rigid:m2e0zgR13NeDG4MUhAuIcF+LZLc	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BUN8	uniprotkb:P16435	intact:EBI-398977|uniprotkb:B3KW41|uniprotkb:E9PH19|ensembl:ENSP00000259512	intact:EBI-726554|uniprotkb:Q9UDT3|uniprotkb:Q16455|uniprotkb:Q8N181|uniprotkb:Q9H3M8|uniprotkb:Q197M5|ensembl:ENSP00000378355|ensembl:ENSP00000389409|ensembl:ENSP00000389719|ensembl:ENSP00000390540|ensembl:ENSP00000395813|ensembl:ENSP00000399327|ensembl:ENSP00000399556|ensembl:ENSP00000404731|ensembl:ENSP00000409238|ensembl:ENSP00000414263|ensembl:ENSP00000419970	psi-mi:derl1_human(display_long)|uniprotkb:DERL1(gene name)|psi-mi:DERL1(display_short)|uniprotkb:UNQ243/PRO276(orf name)|uniprotkb:Der1-like protein 1(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:DER1(gene name synonym)	psi-mi:ncpr_human(display_long)|uniprotkb:POR(gene name)|psi-mi:POR(display_short)|uniprotkb:CYPOR(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770511|imex:IM-28143-92	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128143.1|refseq:NP_077271.1|ensembl:ENSG00000136986(gene)|ensembl:ENST00000259512(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002020"(protease binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0036502"(Derlin-1-VIMP complex)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|rcsb pdb:5GLF|rcsb pdb:7CZB|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5678895|reactome:R-HSA-8866654	refseq:NP_000932.3|ensembl:ENSG00000127948(gene)|ensembl:ENST00000394893(transcript)|ensembl:ENST00000412064(transcript)|ensembl:ENST00000412521(transcript)|ensembl:ENST00000414186(transcript)|ensembl:ENST00000418341(transcript)|ensembl:ENST00000432753(transcript)|ensembl:ENST00000439963(transcript)|ensembl:ENST00000449920(transcript)|ensembl:ENST00000453773(transcript)|ensembl:ENST00000454934(transcript)|ensembl:ENST00000461988(transcript)|go:"GO:0003420"(regulation of growth plate cartilage chondrocyte proliferation)|go:"GO:0003958"(NADPH-hemoprotein reductase activity)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008941"(nitric oxide dioxygenase activity)|go:"GO:0009055"(electron transfer activity)|go:"GO:0009437"(carnitine metabolic process)|go:"GO:0009725"(response to hormone)|go:"GO:0009812"(flavonoid metabolic process)|go:"GO:0010181"(FMN binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0016787"(hydrolase activity)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0019899"(enzyme binding)|go:"GO:0022900"(electron transport chain)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032770"(positive regulation of monooxygenase activity)|go:"GO:0042493"|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043602"(nitrate catabolic process)|go:"GO:0045542"(positive regulation of cholesterol biosynthetic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046210"(nitric oxide catabolic process)|go:"GO:0047726"(iron-cytochrome-c reductase activity)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:0060192"(negative regulation of lipase activity)|go:"GO:0070988"(demethylation)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090031"(positive regulation of steroid hormone biosynthetic process)|go:"GO:0090346"(cellular organofluorine metabolic process)|interpro:IPR001094(Flavodoxin-like)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023173|interpro:IPR023208|interpro:IPR029039|interpro:IPR039261|rcsb pdb:1B1C|rcsb pdb:3FJO|rcsb pdb:3QE2|rcsb pdb:3QFC|rcsb pdb:3QFR|rcsb pdb:3QFS|rcsb pdb:3QFT|rcsb pdb:5EMN|rcsb pdb:5FA6|reactome:R-HSA-211897|dip:DIP-29682N|genbank_nucl_gi:127139033(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:M35Ah+CuYuV7RP1edsda6vU7Bgo9606	rogid:Tgl0hfwgwo16Yw+kH4JIdIaRPpM9606	rigid:m2e0zgR13NeDG4MUhAuIcF+LZLc	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BUN8	uniprotkb:P07099	intact:EBI-398977|uniprotkb:B3KW41|uniprotkb:E9PH19|ensembl:ENSP00000259512	intact:EBI-6138796|uniprotkb:B2R8N0|uniprotkb:Q5VTJ6|uniprotkb:Q9NP75|uniprotkb:Q9NPE7|uniprotkb:Q9NQU6|uniprotkb:Q9NQU7|uniprotkb:Q9NQU8|uniprotkb:Q9NQU9|uniprotkb:Q9NQV0|uniprotkb:Q9NQV1|uniprotkb:Q9NQV2|ensembl:ENSP00000272167|ensembl:ENSP00000355802|ensembl:ENSP00000480004	psi-mi:derl1_human(display_long)|uniprotkb:DERL1(gene name)|psi-mi:DERL1(display_short)|uniprotkb:UNQ243/PRO276(orf name)|uniprotkb:Der1-like protein 1(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:DER1(gene name synonym)	psi-mi:hyep_human(display_long)|uniprotkb:EPHX1(gene name)|psi-mi:EPHX1(display_short)|uniprotkb:EPHX(gene name synonym)|uniprotkb:EPOX(gene name synonym)|uniprotkb:Epoxide hydratase(gene name synonym)|uniprotkb:Microsomal epoxide hydrolase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770511|imex:IM-28143-92	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128143.1|refseq:NP_077271.1|ensembl:ENSG00000136986(gene)|ensembl:ENST00000259512(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002020"(protease binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0036502"(Derlin-1-VIMP complex)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|rcsb pdb:5GLF|rcsb pdb:7CZB|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5678895|reactome:R-HSA-8866654	refseq:NP_001278092.1|refseq:NP_000111.1|refseq:NP_001129490.1|ensembl:ENSG00000143819(gene)|ensembl:ENST00000272167(transcript)|ensembl:ENST00000366837(transcript)|ensembl:ENST00000614058(transcript)|go:"GO:0004301"(epoxide hydrolase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019439"(aromatic compound catabolic process)|go:"GO:0033961"(cis-stilbene-oxide hydrolase activity)|go:"GO:0097176"(epoxide metabolic process)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000639(Epoxide hydrolase-like)|interpro:IPR016292(Epoxide hydrolase)|interpro:IPR029058|reactome:R-HSA-211945|genbank_nucl_gi:123926(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:M35Ah+CuYuV7RP1edsda6vU7Bgo9606	rogid:VtIgDuQpQQbLSdFLOBBx9yHHiBE9606	rigid:m2e0zgR13NeDG4MUhAuIcF+LZLc	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BUN8	uniprotkb:P09601	intact:EBI-398977|uniprotkb:B3KW41|uniprotkb:E9PH19|ensembl:ENSP00000259512	intact:EBI-2806151|ensembl:ENSP00000216117	psi-mi:derl1_human(display_long)|uniprotkb:DERL1(gene name)|psi-mi:DERL1(display_short)|uniprotkb:UNQ243/PRO276(orf name)|uniprotkb:Der1-like protein 1(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:DER1(gene name synonym)	psi-mi:hmox1_human(display_long)|uniprotkb:HO(gene name synonym)|uniprotkb:HO1(gene name synonym)|uniprotkb:HMOX1(gene name)|psi-mi:HMOX1(display_short)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770511|imex:IM-28143-92	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128143.1|refseq:NP_077271.1|ensembl:ENSG00000136986(gene)|ensembl:ENST00000259512(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002020"(protease binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0036502"(Derlin-1-VIMP complex)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|rcsb pdb:5GLF|rcsb pdb:7CZB|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5678895|reactome:R-HSA-8866654	rcsb pdb:6EHA|reactome:R-HSA-189483|reactome:R-HSA-6785807|reactome:R-HSA-844456|reactome:R-HSA-917937|reactome:R-HSA-9609523|reactome:R-HSA-9660826|reactome:R-HSA-9707564|reactome:R-HSA-9707587|reactome:R-HSA-9707616|refseq:NP_002124.1|ensembl:ENSG00000100292(gene)|ensembl:ENST00000216117(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002246"(wound healing involved in inflammatory response)|go:"GO:0002686"(negative regulation of leukocyte migration)|go:"GO:0004392"("heme oxygenase (decyclizing) activity")|go:"GO:0004630"(phospholipase D activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005901"(caveola)|go:"GO:0006788"(heme oxidation)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007588"(excretion)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008219"(cell death)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010656"(negative regulation of muscle cell apoptotic process)|go:"GO:0014806"(smooth muscle hyperplasia)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032764"(negative regulation of mast cell cytokine production)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0034395"(regulation of transcription from RNA polymerase II promoter in response to iron)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035094"(response to nicotine)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043305"(negative regulation of mast cell degranulation)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0043627"(response to estrogen)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072719"(cellular response to cisplatin)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0097421"(liver regeneration)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903589"(positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1904036"(negative regulation of epithelial cell apoptotic process)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|interpro:IPR002051(Haem oxygenase)|interpro:IPR016053(Haem oxygenase-like)|interpro:IPR016084(Haem oxygenase-like, multi-helical)|interpro:IPR018207|rcsb pdb:1N3U|rcsb pdb:1N45|rcsb pdb:1NI6|rcsb pdb:1OYK|rcsb pdb:1OYL|rcsb pdb:1OZE|rcsb pdb:1OZL|rcsb pdb:1OZR|rcsb pdb:1OZW|rcsb pdb:1S13|rcsb pdb:1S8C|rcsb pdb:1T5P|rcsb pdb:1TWN|rcsb pdb:1TWR|rcsb pdb:1XJZ|rcsb pdb:1XK0|rcsb pdb:1XK1|rcsb pdb:1XK2|rcsb pdb:1XK3|rcsb pdb:3CZY|rcsb pdb:3HOK|rcsb pdb:3K4F|rcsb pdb:3TGM|rcsb pdb:4WD4|rcsb pdb:5BTQ|go:"GO:0042167"(heme catabolic process)|genbank_nucl_gi:123446(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:M35Ah+CuYuV7RP1edsda6vU7Bgo9606	rogid:Qrwo0mQGREIpHf3DLrvyO6DOLKM9606	rigid:m2e0zgR13NeDG4MUhAuIcF+LZLc	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BUN8	uniprotkb:A0FGR8	intact:EBI-398977|uniprotkb:B3KW41|uniprotkb:E9PH19|ensembl:ENSP00000259512	intact:EBI-3184170|uniprotkb:Q9ULJ2|uniprotkb:Q9NW47|uniprotkb:Q69YJ2|uniprotkb:Q6ZVU1|uniprotkb:Q6UKI4|uniprotkb:Q6ZTU0|uniprotkb:Q9BQS0|uniprotkb:A4D229	psi-mi:derl1_human(display_long)|uniprotkb:DERL1(gene name)|psi-mi:DERL1(display_short)|uniprotkb:UNQ243/PRO276(orf name)|uniprotkb:Der1-like protein 1(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:DER1(gene name synonym)	psi-mi:esyt2_human(display_long)|uniprotkb:ESYT2(gene name)|psi-mi:ESYT2(display_short)|uniprotkb:FAM62B(gene name synonym)|uniprotkb:KIAA1228(gene name synonym)|uniprotkb:Chr2Syt(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770511|imex:IM-28143-92	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128143.1|refseq:NP_077271.1|ensembl:ENSG00000136986(gene)|ensembl:ENST00000259512(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002020"(protease binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0036502"(Derlin-1-VIMP complex)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|rcsb pdb:5GLF|rcsb pdb:7CZB|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5678895|reactome:R-HSA-8866654	go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016020"(membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0045296"(cadherin binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0140268"(endoplasmic reticulum-plasma membrane contact site)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR031468|interpro:IPR035892|go:"GO:0005789"(endoplasmic reticulum membrane)|interpro:IPR037733|interpro:IPR037749|interpro:IPR037752|interpro:IPR039010|rcsb pdb:2DMG|rcsb pdb:4NPJ|rcsb pdb:4NPK|rcsb pdb:4P42|reactome:R-HSA-1660662|refseq:NP_065779.1|mint:A0FGR8|dip:DIP-61039N|genbank_nucl_gi:121949310(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:M35Ah+CuYuV7RP1edsda6vU7Bgo9606	rogid:mOkUWt8oia02xtJYM6gQz3tsav89606	rigid:m2e0zgR13NeDG4MUhAuIcF+LZLc	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:Q8NBM4	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770556|imex:IM-28143-54	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1|genbank_nucl_gi:74751173(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rigid:8QncLEDtQka2UPArlxRdoqCX8Ys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:Q96CS3	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770556|imex:IM-28143-54	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N|genbank_nucl_gi:74731375(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rigid:8QncLEDtQka2UPArlxRdoqCX8Ys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:Q8WY22	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-359348|uniprotkb:Q8WY23|ensembl:ENSP00000340761|ensembl:ENSP00000500359	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:bri3b_human(display_long)|uniprotkb:BRI3BP(gene name)|psi-mi:BRI3BP(display_short)|uniprotkb:KG19(gene name synonym)|uniprotkb:Cervical cancer 1 proto-oncogene-binding protein KG19(gene name synonym)|uniprotkb:HCCRBP-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770556|imex:IM-28143-54	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_542193.3|ensembl:ENSG00000184992(gene)|ensembl:ENST00000341446(transcript)|ensembl:ENST00000672415(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR033367|genbank_nucl_gi:74730999(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:O9epHcfM1m7xNvrm6ELo0fRRGV49606	rigid:8QncLEDtQka2UPArlxRdoqCX8Ys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:O75477	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-359299|uniprotkb:B0QZ42|uniprotkb:Q53HV0|ensembl:ENSP00000384900|ensembl:ENSP00000410964|intact:EBI-21351077|uniprotkb:D3DR65	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:erln1_human(display_long)|uniprotkb:KEO4(gene name synonym)|uniprotkb:ERLIN1(gene name)|psi-mi:ERLIN1(display_short)|uniprotkb:C10orf69(gene name synonym)|uniprotkb:KE04(gene name synonym)|uniprotkb:SPFH1(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 1(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1(gene name synonym)|uniprotkb:Protein KE04(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770556|imex:IM-28143-54	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_001094096.1|refseq:NP_006450.2|ensembl:ENSG00000107566(gene)|ensembl:ENST00000407654(transcript)|ensembl:ENST00000421367(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O75477|reactome:R-HSA-382556|reactome:R-HSA-5678895|refseq:NP_001334786.1|refseq:NP_001334788.1|refseq:NP_001334789.1|refseq:NP_001334790.1|genbank_nucl_gi:67461552(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:HycFhL5qL5GLmaIIc9NtTcBbu1M9606	rigid:8QncLEDtQka2UPArlxRdoqCX8Ys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:P35579	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-350338|uniprotkb:O60805|ensembl:ENSP00000216181|uniprotkb:Q86T83|intact:EBI-1054343|uniprotkb:A8K6E4|uniprotkb:Q60FE2	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:myh9_human(display_long)|uniprotkb:MYH9(gene name)|psi-mi:MYH9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770556|imex:IM-28143-54	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_002464.1|ensembl:ENSG00000100345(gene)|ensembl:ENST00000216181(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001931"(uropod)|go:"GO:0003723"(RNA binding)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|refseq:XP_011528499.1|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030220"(platelet formation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032418"(lysosome localization)|go:"GO:0032506"(cytokinetic process)|go:"GO:0032796"(uropod organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045296"(cadherin binding)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051015"(actin filament binding)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0097513"(myosin II filament)|go:"GO:1903919"(negative regulation of actin filament severing)|rcsb pdb:4CFR|rcsb pdb:4ETO|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9662834|reactome:R-HSA-9664422|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1905684"(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036305|interpro:IPR036961|mint:P35579|rcsb pdb:2LNK|rcsb pdb:3ZWH|rcsb pdb:4CFQ|refseq:XP_016884292.1|refseq:XP_016884293.1|refseq:XP_016884294.1|refseq:XP_016884295.1|dip:DIP-33103N|genbank_nucl_gi:6166599(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:fSOtpFpr8PSnAG5UdAr/khwkzJs9606	rigid:8QncLEDtQka2UPArlxRdoqCX8Ys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:P55072	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770556|imex:IM-28143-54	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N|genbank_nucl_gi:6094447(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606	rigid:8QncLEDtQka2UPArlxRdoqCX8Ys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:P35998	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-359710|uniprotkb:B7Z5E2|uniprotkb:A4D0Q1|uniprotkb:Q3LIA5|uniprotkb:Q9UDI3|ensembl:ENSP00000292644|ensembl:ENSP00000391211|ensembl:ENSP00000502939|ensembl:ENSP00000503179|ensembl:ENSP00000504608	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:prs7_human(display_long)|uniprotkb:PSMC2(gene name)|psi-mi:PSMC2(display_short)|uniprotkb:MSS1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 2(gene name synonym)|uniprotkb:Protein MSS1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770556|imex:IM-28143-54	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_001191382.1|refseq:NP_002794.1|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR035245|interpro:IPR041569|mint:P35998|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|interpro:IPR003960(AAA ATPase, conserved site)|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|ensembl:ENSG00000161057(gene)|ensembl:ENST00000292644(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|ensembl:ENST00000435765(transcript)|ensembl:ENST00000678493(transcript)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|ensembl:ENST00000679205(transcript)|ensembl:ENST00000679341(transcript)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0043197"(dendritic spine)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5VHQ|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5610780|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|dip:DIP-27554N|genbank_nucl_gi:547930(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:ahQfjPKywP5DWNq3FB5XCjuqkJ09606	rigid:8QncLEDtQka2UPArlxRdoqCX8Ys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:O00487	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-722193|uniprotkb:O00176|uniprotkb:B3KNW2|ensembl:ENSP00000386541	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:psde_human(display_long)|uniprotkb:26S proteasome regulatory subunit RPN11(gene name synonym)|uniprotkb:26S proteasome-associated PAD1 homolog 1(gene name synonym)|uniprotkb:PSMD14(gene name)|psi-mi:PSMD14(display_short)|uniprotkb:POH1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770556|imex:IM-28143-54	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_005796.1|ensembl:ENSG00000115233(gene)|ensembl:ENST00000409682(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070628"(proteasome binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR035299|interpro:IPR037518|mint:O00487|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|genbank_nucl_gi:51701716(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:pSM+755ZbQisR5S0ZivcYBu9Bc49606	rigid:8QncLEDtQka2UPArlxRdoqCX8Ys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:P60900	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-357793|uniprotkb:P34062|uniprotkb:Q6IB60|uniprotkb:B2R7J9|uniprotkb:B4DQR4|uniprotkb:B4DXJ9|ensembl:ENSP00000261479	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:psa6_human(display_long)|uniprotkb:PSMA6(gene name)|psi-mi:PSMA6(display_short)|uniprotkb:PROS27(gene name synonym)|uniprotkb:Proteasome iota chain(gene name synonym)|uniprotkb:Macropain iota chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex iota chain(gene name synonym)|uniprotkb:27 kDa prosomal protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770556|imex:IM-28143-54	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_002782.1|refseq:NP_001269162.1|refseq:NP_001269163.1|refseq:XP_016876957.1|refseq:NP_001269161.1|ensembl:ENSG00000100902(gene)|ensembl:ENST00000261479(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0035639"(purine ribonucleoside triphosphate binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034642|mint:P60900|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-29367N|genbank_nucl_gi:46397659(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:F+Kwr6rnDS3jD53gBGHDIn7HV/89606	rigid:8QncLEDtQka2UPArlxRdoqCX8Ys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:P28074	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-357828|uniprotkb:Q16242|uniprotkb:Q6PEW2|intact:EBI-1237472|uniprotkb:Q7Z3B5|uniprotkb:Q9TNN9|uniprotkb:B2R4N9|uniprotkb:D3DS43|uniprotkb:B4DUM9|uniprotkb:Q86T01|uniprotkb:E9PAV2|ensembl:ENSP00000355325	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:psb5_human(display_long)|uniprotkb:PSMB5(gene name)|psi-mi:PSMB5(display_short)|uniprotkb:LMPX(gene name synonym)|uniprotkb:Proteasome epsilon chain(gene name synonym)|uniprotkb:Macropain epsilon chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex epsilon chain(gene name synonym)|uniprotkb:Proteasome subunit X(gene name synonym)|uniprotkb:Proteasome chain 6(gene name synonym)|uniprotkb:Proteasome subunit MB1(gene name synonym)|uniprotkb:MB1(gene name synonym)|uniprotkb:X(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770556|imex:IM-28143-54	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_001124197.1|refseq:NP_001138404.1|refseq:NP_002788.1|dip:DIP-27540N|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5610785|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|ensembl:ENSG00000100804(gene)|ensembl:ENST00000361611(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006508"(proteolysis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008233"(peptidase activity)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|mint:P28074|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|genbank_nucl_gi:4506201(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:73T59wniLri/465F3BhBvwL1/LM9606	rigid:8QncLEDtQka2UPArlxRdoqCX8Ys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:Q14997	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-1236916|uniprotkb:Q1XBG4|uniprotkb:Q1XBG5|uniprotkb:Q1XBG6|uniprotkb:Q2M1Z0|uniprotkb:Q6IPR2|uniprotkb:Q86XF8|ensembl:ENSP00000384211	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:psme4_human(display_long)|uniprotkb:PSME4(gene name)|psi-mi:PSME4(display_short)|uniprotkb:KIAA0077(gene name synonym)|uniprotkb:Proteasome activator PA200(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770556|imex:IM-28143-54	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_055429.2|dip:DIP-38203N|ensembl:ENSG00000068878(gene)|ensembl:ENST00000404125(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0035093"(spermatogenesis, exchange of chromosomal proteins)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070628"(proteasome binding)|go:"GO:1990111"(spermatoproteasome complex)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021843|interpro:IPR032430|interpro:IPR035309|mint:Q14997|rcsb pdb:6KWX|rcsb pdb:6KWY|rcsb pdb:6REY|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-983168|reactome:R-HSA-8932339|genbank_nucl_gi:40788003(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:wKVv+GwMVpoOZZS1eNP+rDe85tE9606	rigid:8QncLEDtQka2UPArlxRdoqCX8Ys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:Q9BZF1	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-2684038|uniprotkb:Q52LQ3|uniprotkb:Q9P277|uniprotkb:Q8WXP8|uniprotkb:A8K1T2|uniprotkb:E9PE66|uniprotkb:E9PE68|uniprotkb:Q68D75|ensembl:ENSP00000261183	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:osbl8_human(display_long)|uniprotkb:KIAA1451(gene name synonym)|uniprotkb:ORP8(gene name synonym)|uniprotkb:OSBP10(gene name synonym)|uniprotkb:OSBPL8(gene name)|psi-mi:OSBPL8(display_short)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770556|imex:IM-28143-54	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_001003712.1|refseq:NP_065892.1|refseq:NP_001306581.1|refseq:NP_001306584.1|ensembl:ENSG00000091039(gene)|ensembl:ENST00000261183(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015914"(phospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0036150"(phosphatidylserine acyl-chain remodeling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0090204"(protein localization to nuclear pore)|go:"GO:0140343"(phosphatidylserine transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|mint:Q9BZF1|rcsb pdb:1V88|rcsb pdb:5U77|rcsb pdb:5U78|reactome:R-HSA-1482801|refseq:XP_005268678.1|refseq:XP_006719287.1|dip:DIP-56130N|genbank_nucl_gi:39932732(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:KwZ5DFeGTIM3p/yP3XBNgr/v3O09606	rigid:8QncLEDtQka2UPArlxRdoqCX8Ys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:P28066	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-355475|uniprotkb:B4E2V4|uniprotkb:Q6IBF7|uniprotkb:Q3T1C1|uniprotkb:B2R8F6|ensembl:ENSP00000271308	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:psa5_human(display_long)|uniprotkb:PSMA5(gene name)|psi-mi:PSMA5(display_short)|uniprotkb:Proteasome zeta chain(gene name synonym)|uniprotkb:Macropain zeta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex zeta chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770556|imex:IM-28143-54	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_001186701.1|refseq:NP_001186702.1|refseq:NP_001186703.1|refseq:NP_002781.2|ensembl:ENSG00000143106(gene)|ensembl:ENST00000271308(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR033812|mint:P28066|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEY|rcsb pdb:5LEX|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-29368N|genbank_nucl_gi:38258905(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:bfMG3npzVetUH1tahr2MAI4R+3g9606	rigid:8QncLEDtQka2UPArlxRdoqCX8Ys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:O94905	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-4400770|uniprotkb:A0JLQ1|uniprotkb:A8K5S9|uniprotkb:B4DM38|uniprotkb:D3DSW0|uniprotkb:Q6NW21|uniprotkb:Q86VS6|uniprotkb:Q86W49|ensembl:ENSP00000428112	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:erln2_human(display_long)|uniprotkb:ERLIN2(gene name)|psi-mi:ERLIN2(display_short)|uniprotkb:C8orf2(gene name synonym)|uniprotkb:SPFH2(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 2(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2(gene name synonym)|uniprotkb:UNQ2441/PRO5003/PRO9924(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770556|imex:IM-28143-54	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_001003790.1|refseq:NP_001003791.1|refseq:NP_009106.1|refseq:XP_016868489.1|refseq:XP_005273449.1|ensembl:ENSG00000147475(gene)|ensembl:ENST00000519638(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045121"(membrane raft)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O94905|reactome:R-HSA-382556|reactome:R-HSA-5655302|reactome:R-HSA-5678895|reactome:R-HSA-8853336|genbank_nucl_gi:38257366(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:Evjg3G0FFeQ499BNlJxpK6t8to89606	rigid:8QncLEDtQka2UPArlxRdoqCX8Ys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:Q9BVT8	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-11425701|uniprotkb:D3DX06|uniprotkb:Q53AQ2|ensembl:ENSP00000297533|ensembl:ENSP00000376565|ensembl:ENSP00000417519|ensembl:ENSP00000418709|ensembl:ENSP00000419214	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:tmub1_human(display_long)|uniprotkb:TMUB1(gene name)|psi-mi:TMUB1(display_short)|uniprotkb:C7orf21(gene name synonym)|uniprotkb:DULP(gene name synonym)|uniprotkb:HOPS(gene name synonym)|uniprotkb:Dendritic cell-derived ubiquitin-like protein(gene name synonym)|uniprotkb:Hepatocyte odd protein shuttling protein(gene name synonym)|uniprotkb:Ubiquitin-like protein SB144(gene name synonym)|uniprotkb:SB144(orf name)|uniprotkb:UNQ763/PRO1555(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770556|imex:IM-28143-54	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_001129516.1|refseq:NP_113622.1|ensembl:ENSG00000164897(gene)|ensembl:ENST00000297533(transcript)|ensembl:ENST00000392818(transcript)|ensembl:ENST00000462940(transcript)|ensembl:ENST00000476627(transcript)|ensembl:ENST00000482202(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0055037"(recycling endosome)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR040352|genbank_nucl_gi:34922062(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:n89Hgo8fzSg9u5u2upp7+Prodiw9606	rigid:8QncLEDtQka2UPArlxRdoqCX8Ys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:P60604	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-1051028|uniprotkb:P56554|uniprotkb:A8K3L4|uniprotkb:D3DSL7|uniprotkb:A6NMQ7|ensembl:ENSP00000338348	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:ub2g2_human(display_long)|uniprotkb:Ubiquitin-protein ligase G2(gene name synonym)|uniprotkb:Ubiquitin carrier protein G2(gene name synonym)|uniprotkb:UBE2G2(gene name)|psi-mi:UBE2G2(display_short)|uniprotkb:E2 ubiquitin-conjugating enzyme G2(gene name synonym)|uniprotkb:UBC7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770556|imex:IM-28143-54	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_001189418.1|refseq:NP_003334.2|refseq:NP_872630.1|refseq:XP_016883958.1|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2CYX|rcsb pdb:2KLY|rcsb pdb:2LXP|rcsb pdb:3H8K|rcsb pdb:4LAD|reactome:R-HSA-8866652|reactome:R-HSA-983168|ensembl:ENSG00000184787(gene)|ensembl:ENST00000345496(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-50750N|genbank_nucl_gi:33359701(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:Q/uslqX/WH/SxKEPYeMmU9CjTBI9606	rigid:8QncLEDtQka2UPArlxRdoqCX8Ys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:Q15008	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-359701|uniprotkb:E9PHI9|uniprotkb:A8K2E0|ensembl:ENSP00000295901|uniprotkb:Q6UV22	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:psmd6_human(display_long)|uniprotkb:PSMD6(gene name)|psi-mi:PSMD6(display_short)|uniprotkb:KIAA0107(gene name synonym)|uniprotkb:PFAAP4(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S10(gene name synonym)|uniprotkb:p42A(gene name synonym)|uniprotkb:Proteasome regulatory particle subunit p44S10(gene name synonym)|uniprotkb:Phosphonoformate immuno-associated protein 4(gene name synonym)|uniprotkb:Breast cancer-associated protein SGA-113M(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770556|imex:IM-28143-54	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_055629.1|ensembl:ENSG00000163636(gene)|ensembl:ENST00000295901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019585|interpro:IPR035268|interpro:IPR036390|mint:Q15008|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|reactome:R-HSA-5358346|reactome:R-HSA-1236978|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-1236974|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-69601|reactome:R-HSA-69481|refseq:NP_001258708.1|refseq:NP_001258709.1|refseq:NP_001258710.1|dip:DIP-27590N|genbank_nucl_gi:2494625(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:ULOM02v6J56vZLlAGn7wN3N6Efw9606	rigid:8QncLEDtQka2UPArlxRdoqCX8Ys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:P49720	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-603340|uniprotkb:P31147|uniprotkb:Q0P6J7|uniprotkb:Q96E27|ensembl:ENSP00000483688|ensembl:ENSP00000483956	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:psb3_human(display_long)|uniprotkb:PSMB3(gene name)|psi-mi:PSMB3(display_short)|uniprotkb:Proteasome theta chain(gene name synonym)|uniprotkb:Proteasome chain 13(gene name synonym)|uniprotkb:Proteasome component C10-II(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770556|imex:IM-28143-54	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_002786.2|dip:DIP-33846N|ensembl:ENSG00000275903(gene)|ensembl:ENSG00000277791(gene)|ensembl:ENST00000619426(transcript)|ensembl:ENST00000619951(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR033811|mint:P49720|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|genbank_nucl_gi:20532411(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:H4UDdXV1BaXHp6mEPafNy+Iv8389606	rigid:8QncLEDtQka2UPArlxRdoqCX8Ys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:P28072	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-359288|uniprotkb:Q96J55|ensembl:ENSP00000270586	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:psb6_human(display_long)|uniprotkb:PSMB6(gene name)|psi-mi:PSMB6(display_short)|uniprotkb:LMPY(gene name synonym)|uniprotkb:Proteasome delta chain(gene name synonym)|uniprotkb:Macropain delta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex delta chain(gene name synonym)|uniprotkb:Proteasome subunit Y(gene name synonym)|uniprotkb:Y(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770556|imex:IM-28143-54	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_002789.1|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035140|mint:P28072|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|go:"GO:0005737"(cytoplasm)|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000142507(gene)|ensembl:ENST00000270586(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-33847N|genbank_nucl_gi:20532407(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:4LRxYA6/tM2hsc96iP29c5J7ew49606	rigid:8QncLEDtQka2UPArlxRdoqCX8Ys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:O43242	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-357622|uniprotkb:Q96EI2|uniprotkb:Q9BQA4|ensembl:ENSP00000264639|uniprotkb:B4DT72|uniprotkb:B3KMW9	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:psmd3_human(display_long)|uniprotkb:PSMD3(gene name)|psi-mi:PSMD3(display_short)|uniprotkb:Proteasome subunit p58(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S3(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770556|imex:IM-28143-54	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	ensembl:ENSG00000108344(gene)|ensembl:ENST00000264639(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013586(26S proteasome regulatory subunit, C-terminal)|interpro:IPR035267|interpro:IPR036390|mint:O43242|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|reactome:R-HSA-174113|reactome:R-HSA-174154|rcsb pdb:5VHH|rcsb pdb:5VHI|reactome:R-HSA-174178|rcsb pdb:5VHS|reactome:R-HSA-174184|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|reactome:R-HSA-180534|rcsb pdb:6MSJ|reactome:R-HSA-180585|reactome:R-HSA-187577|rcsb pdb:6MSK|reactome:R-HSA-195253|reactome:R-HSA-202424|rcsb pdb:6WJD|reactome:R-HSA-211733|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-174084|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5607761|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-8854050|refseq:NP_002800.2|dip:DIP-27571N|genbank_nucl_gi:20532405(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:C6CStW89nIAA3mzubyv5wfBwPHk9606	rigid:8QncLEDtQka2UPArlxRdoqCX8Ys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:Q99436	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-603319|uniprotkb:Q96AG8|uniprotkb:Q9BWA7|uniprotkb:B4E0P1|uniprotkb:Q5TBG6|ensembl:ENSP00000259457	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:psb7_human(display_long)|uniprotkb:PSMB7(gene name)|psi-mi:PSMB7(display_short)|uniprotkb:Proteasome subunit Z(gene name synonym)|uniprotkb:Macropain chain Z(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain Z(gene name synonym)|uniprotkb:Z(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770556|imex:IM-28143-54	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_002790.1|dip:DIP-33843N|ensembl:ENSG00000136930(gene)|ensembl:ENST00000259457(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016604"(nuclear body)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR024689|interpro:IPR029055|interpro:IPR035216|mint:Q99436|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|genbank_nucl_gi:17380263(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:w880QftOor3RdaGvhCup7apz2OM9606	rigid:8QncLEDtQka2UPArlxRdoqCX8Ys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:P49721	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-359335|uniprotkb:P31145|uniprotkb:Q9BWZ9|uniprotkb:D3DPS0|ensembl:ENSP00000362334	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:psb2_human(display_long)|uniprotkb:PSMB2(gene name)|psi-mi:PSMB2(display_short)|uniprotkb:Multicatalytic endopeptidase complex subunit C7-I(gene name synonym)|uniprotkb:Proteasome component C7-I(gene name synonym)|uniprotkb:Macropain subunit C7-I(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770556|imex:IM-28143-54	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_002785.1|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5GJR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-5689603|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000126067(gene)|ensembl:ENST00000373237(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|mint:P49721|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|dip:DIP-33848N|genbank_nucl_gi:1709762(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:PvXrk6RLayQ1zqmavn1cONfA9/A9606	rigid:8QncLEDtQka2UPArlxRdoqCX8Ys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:P35580	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-351758|intact:EBI-7850240|intact:MINT-8330016|uniprotkb:B2RWP9|uniprotkb:D3DTS1|uniprotkb:Q9BWG0|uniprotkb:Q12989|uniprotkb:Q16087|uniprotkb:Q149N3|ensembl:ENSP00000269243|uniprotkb:Q149N4|uniprotkb:Q6PK16|uniprotkb:F8VTL3|uniprotkb:Q4LE45	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:myh10_human(display_long)|uniprotkb:MYH10(gene name)|psi-mi:MYH10(display_short)|uniprotkb:Myosin heavy chain 10(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIb(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIb(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type B(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770556|imex:IM-28143-54	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_001243024.1|refseq:NP_001242941.1|refseq:NP_005955.3|ensembl:ENSG00000133026(gene)|ensembl:ENST00000269243(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016459"(myosin complex)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030496"(midbody)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0042641"(actomyosin)|go:"GO:0043531"(ADP binding)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097513"(myosin II filament)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036961|mint:P35580|rcsb pdb:4PD3|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|refseq:XP_016880169.1|refseq:XP_016880170.1|refseq:XP_016880171.1|dip:DIP-31110N|genbank_nucl_gi:1346640(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:iSHfJZbrWg1L+vSpu1n7RmTTNN49606	rigid:8QncLEDtQka2UPArlxRdoqCX8Ys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:P25789	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-359310|uniprotkb:Q8TBD1|uniprotkb:Q53XP2|ensembl:ENSP00000044462|ensembl:ENSP00000453887|uniprotkb:D3DW86|uniprotkb:Q567Q5	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:psa4_human(display_long)|uniprotkb:PSMA4(gene name)|psi-mi:PSMA4(display_short)|uniprotkb:PSC9(gene name synonym)|uniprotkb:Proteasome component C9(gene name synonym)|uniprotkb:Macropain subunit C9(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C9(gene name synonym)|uniprotkb:Proteasome subunit L(gene name synonym)|uniprotkb:HC9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770556|imex:IM-28143-54	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_001096137.1|refseq:NP_002780.1|rcsb pdb:6XMJ|reactome:R-HSA-2467813|reactome:R-HSA-2871837|rcsb pdb:7AWE|reactome:R-HSA-349425|reactome:R-HSA-1169091|reactome:R-HSA-350562|reactome:R-HSA-1234176|reactome:R-HSA-382556|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-450408|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-4641258|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5358346|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000041357(gene)|ensembl:ENST00000044462(transcript)|ensembl:ENST00000559082(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034647|mint:P25789|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|refseq:NP_001096138.1|refseq:NP_001317605.1|dip:DIP-29365N|genbank_nucl_gi:130861(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:u+wKxvIa9JKb4Zu9K+tnY3d26tw9606	rigid:8QncLEDtQka2UPArlxRdoqCX8Ys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:P25788	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-348380|ensembl:ENSP00000216455|uniprotkb:Q86U83|uniprotkb:Q8N1D8|uniprotkb:Q9BS70|uniprotkb:B2RCK6	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:psa3_human(display_long)|uniprotkb:PSMA3(gene name)|psi-mi:PSMA3(display_short)|uniprotkb:PSC8(gene name synonym)|uniprotkb:Proteasome component C8(gene name synonym)|uniprotkb:Macropain subunit C8(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C8(gene name synonym)|uniprotkb:HC8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770556|imex:IM-28143-54	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_002779.1|refseq:NP_687033.1|ensembl:ENSG00000100567(gene)|ensembl:ENST00000216455(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0045202"(synapse)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR037555|mint:P25788|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|rcsb pdb:5DSV|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|rcsb pdb:7E55|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|rcsb pdb:5T0H|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-174084|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-174113|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|dip:DIP-29366N|genbank_nucl_gi:130859(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:9Er/PY50/GVoCr5yAPXlkfxtP0k9606	rigid:8QncLEDtQka2UPArlxRdoqCX8Ys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:P20618	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-372273|uniprotkb:Q9BWA8|ensembl:ENSP00000262193|uniprotkb:B5BU76	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:psb1_human(display_long)|uniprotkb:PSMB1(gene name)|psi-mi:PSMB1(display_short)|uniprotkb:PSC5(gene name synonym)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Macropain subunit C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym)|uniprotkb:Proteasome gamma chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770556|imex:IM-28143-54	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	ensembl:ENSG00000008018(gene)|ensembl:ENST00000262193(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|mint:P20618|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|refseq:NP_002784.1|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M2B|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5LF1|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4608870|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-983168|reactome:R-HSA-9604323|dip:DIP-31193N|genbank_nucl_gi:130853(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:DfIS480BUnqbXus9/KoojdkWgw09606	rigid:8QncLEDtQka2UPArlxRdoqCX8Ys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:P25787	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-603262|uniprotkb:Q9BU45|ensembl:ENSP00000223321|intact:EBI-1237095|uniprotkb:Q6ICS6	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:psa2_human(display_long)|uniprotkb:PSMA2(gene name)|psi-mi:PSMA2(display_short)|uniprotkb:PSC3(gene name synonym)|uniprotkb:Proteasome component C3(gene name synonym)|uniprotkb:Macropain subunit C3(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C3(gene name synonym)|uniprotkb:HC3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770556|imex:IM-28143-54	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	mint:P25787|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|ensembl:ENSG00000106588(gene)|ensembl:ENST00000223321(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0009615"(response to virus)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|refseq:NP_002778.1|dip:DIP-29364N|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|genbank_nucl_gi:130850(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:COncAMXXqT+zAHA/nK+7dweRg9A9606	rigid:8QncLEDtQka2UPArlxRdoqCX8Ys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:P25786	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-359352|uniprotkb:Q9BRV9|uniprotkb:A8K400|uniprotkb:Q53YE8|ensembl:ENSP00000379676	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:psa1_human(display_long)|uniprotkb:PSMA1(gene name)|psi-mi:PSMA1(display_short)|uniprotkb:PROS30(gene name synonym)|uniprotkb:PSC2(gene name synonym)|uniprotkb:Proteasome component C2(gene name synonym)|uniprotkb:Macropain subunit C2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C2(gene name synonym)|uniprotkb:Proteasome nu chain(gene name synonym)|uniprotkb:30 kDa prosomal protein(gene name synonym)|uniprotkb:HC2(gene name synonym)|uniprotkb:NU(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770556|imex:IM-28143-54	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_002777.1|refseq:NP_683877.1|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000129084(gene)|ensembl:ENST00000396394(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|mint:P25786|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|dip:DIP-29369N|genbank_nucl_gi:130848(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:tAADzZ1G9E/0BBeS8vybNx97v7k9606	rigid:8QncLEDtQka2UPArlxRdoqCX8Ys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:O14818	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-603272|uniprotkb:Q9BR53|uniprotkb:Q9H4K5|uniprotkb:Q9UEU8|uniprotkb:B2R515|uniprotkb:Q5JXJ2|ensembl:ENSP00000359910	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:psa7_human(display_long)|uniprotkb:PSMA7(gene name)|psi-mi:PSMA7(display_short)|uniprotkb:Proteasome subunit RC6-1(gene name synonym)|uniprotkb:Proteasome subunit XAPC7(gene name synonym)|uniprotkb:HSPC(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770556|imex:IM-28143-54	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_002783.1|dip:DIP-29363N|ensembl:ENSG00000101182(gene)|ensembl:ENST00000370873(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098794"(postsynapse)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035190|mint:O14818|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|genbank_nucl_gi:12643540(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:J1M+b+VK02BAn2OnZISjjlmO8dc9606	rigid:8QncLEDtQka2UPArlxRdoqCX8Ys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9UKV5	uniprotkb:P28070	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	intact:EBI-603350|uniprotkb:P31148|uniprotkb:Q5SZS5|uniprotkb:Q969L6|uniprotkb:B2R9L3|uniprotkb:Q6IBI4|ensembl:ENSP00000290541	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:psb4_human(display_long)|uniprotkb:PSMB4(gene name)|psi-mi:PSMB4(display_short)|uniprotkb:Macropain beta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex beta chain(gene name synonym)|uniprotkb:Proteasome chain 3(gene name synonym)|uniprotkb:26 kDa prosomal protein(gene name synonym)|uniprotkb:PROS26(gene name synonym)|uniprotkb:Proteasome beta chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770556|imex:IM-28143-54	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	refseq:NP_002787.2|dip:DIP-33844N|ensembl:ENSG00000159377(gene)|ensembl:ENST00000290541(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR016295(Proteasome endopeptidase complex, beta subunit)|interpro:IPR023333|interpro:IPR029055|mint:P28070|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|genbank_nucl_gi:116242733(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rogid:drR+ktPXQK9ep6hs7OYb5SmQnXU9606	rigid:8QncLEDtQka2UPArlxRdoqCX8Ys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15006	uniprotkb:Q8N4V1	intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853	intact:EBI-6163737|ensembl:ENSP00000306220|ensembl:ENSP00000505226|uniprotkb:B2R625|uniprotkb:B4DIY3|uniprotkb:D3DWG7|uniprotkb:Q5JPP7	psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym)	psi-mi:emc5_human(display_long)|uniprotkb:MMGT1(gene name)|psi-mi:MMGT1(display_short)|uniprotkb:TMEM32(gene name synonym)|uniprotkb:Transmembrane protein 32(gene name synonym)|uniprotkb:EMC5(gene name synonym)|uniprotkb:Membrane magnesium transporter 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771009|imex:IM-28143-100	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP	go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-5223345|ensembl:ENSG00000169446(gene)|ensembl:ENST00000305963(transcript)|ensembl:ENST00000679621(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|refseq:NP_775741.1|refseq:NP_001316929.1|genbank_nucl_gi:74751006(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606	rogid:Kq+VEYt+fwoOsEfcgZ1K1vkFFN49606	rigid:DaVpayWmVl38vxZ1ER7C4BDnjLk	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15006	uniprotkb:Q9NPA0	intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853	intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5	psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym)	psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771009|imex:IM-28143-100	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP	ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1|genbank_nucl_gi:74752878(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606	rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606	rigid:DaVpayWmVl38vxZ1ER7C4BDnjLk	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15006	uniprotkb:Q8N766	intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853	intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62	psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym)	psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771009|imex:IM-28143-100	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP	go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1|genbank_nucl_gi:74751081(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606	rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606	rigid:DaVpayWmVl38vxZ1ER7C4BDnjLk	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15006	uniprotkb:Q9BV81	intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853	intact:EBI-2820492|ensembl:ENSP00000248378|ensembl:ENSP00000380322	psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym)	psi-mi:emc6_human(display_long)|uniprotkb:EMC6(gene name)|psi-mi:EMC6(display_short)|uniprotkb:TMEM93(gene name synonym)|uniprotkb:Transmembrane protein 93(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771009|imex:IM-28143-100	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP	refseq:NP_001014764.1|refseq:NP_112588.1|ensembl:ENSG00000127774(gene)|ensembl:ENST00000248378(transcript)|ensembl:ENST00000397133(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0097631"(integral component of omegasome membrane)|interpro:IPR008504(Protein of unknown function DUF786)|interpro:IPR029008|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|go:"GO:0072546"(EMC complex)|genbank_nucl_gi:74733294(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606	rogid:GPnTCJqAA2eIiiP17pgtIhGnpsA9606	rigid:DaVpayWmVl38vxZ1ER7C4BDnjLk	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15006	uniprotkb:Q5UCC4	intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853	intact:EBI-11284388|uniprotkb:Q5UCC6|uniprotkb:Q69YT5|uniprotkb:Q6UWP3|uniprotkb:Q86YL4|uniprotkb:Q8N541|ensembl:ENSP00000334037	psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym)	psi-mi:emc10_human(display_long)|uniprotkb:EMC10(gene name)|psi-mi:EMC10(display_short)|uniprotkb:C19orf63(gene name synonym)|uniprotkb:Hematopoietic signal peptide-containing membrane domain-containing protein 1(gene name synonym)|uniprotkb:INM02(gene name synonym)|uniprotkb:UNQ764/PRO1556(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771009|imex:IM-28143-100	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP	refseq:NP_778233.4|refseq:NP_996261.1|ensembl:ENSG00000161671(gene)|ensembl:ENST00000334976(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005576"(extracellular region)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR029615|mint:Q5UCC4|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|genbank_nucl_gi:74708213(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606	rogid:NEJjkw5uEJnzNUW7MkZIm/ELpA89606	rigid:DaVpayWmVl38vxZ1ER7C4BDnjLk	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q15006	uniprotkb:Q9P0I2	intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853	intact:EBI-1054670|uniprotkb:Q53GH8|uniprotkb:Q6ZMC2|uniprotkb:B2R4Z9|ensembl:ENSP00000245046	psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym)	psi-mi:emc3_human(display_long)|uniprotkb:EMC3(gene name)|psi-mi:EMC3(display_short)|uniprotkb:TMEM111(gene name synonym)|uniprotkb:Transmembrane protein 111(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771009|imex:IM-28143-100	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP	refseq:NP_060917.1|ensembl:ENSG00000125037(gene)|ensembl:ENST00000245046(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008568(Protein of unknown function DUF850, transmembrane eukaryotic)|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-8980692|genbank_nucl_gi:71153383(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606	rogid:VbIl0nFhcDMIPTxmBclaIMtbVU09606	rigid:DaVpayWmVl38vxZ1ER7C4BDnjLk	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y679	uniprotkb:Q9UBV2	intact:EBI-1058701|ensembl:ENSP00000366748|uniprotkb:Q9H866|uniprotkb:Q9UNQ6|uniprotkb:Q9Y685|uniprotkb:C0H5W8	intact:EBI-358766|uniprotkb:Q6UWT6|uniprotkb:Q9P1T9|uniprotkb:Q9UHK7|ensembl:ENSP00000337053	psi-mi:aup1_human(display_long)|uniprotkb:AUP1(gene name)|psi-mi:AUP1(display_short)|uniprotkb:Ancient ubiquitous protein 1(gene name synonym)	psi-mi:se1l1_human(display_long)|uniprotkb:SEL1L(gene name)|psi-mi:SEL1L(display_short)|uniprotkb:TSA305(gene name synonym)|uniprotkb:UNQ128/PRO1063(orf name)|uniprotkb:Suppressor of lin-12-like protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770979|imex:IM-28143-98	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115307(gene)|ensembl:ENST00000377526(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:NP_853553.1|go:"GO:0034389"(lipid droplet organization)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061724"(lipophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:0140042"(lipid droplet formation)|go:"GO:1990044"(protein localization to lipid droplet)|interpro:IPR003892(Ubiquitin system component Cue)|rcsb pdb:2EKF	refseq:NP_001231913.1|refseq:NP_005056.3|ensembl:ENSG00000071537(gene)|ensembl:ENST00000336735(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0050821"(protein stabilization)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|mint:Q9UBV2|reactome:R-HSA-1912420|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-46259N|genbank_nucl_gi:62512184(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:6yySfIPpRUlnm0upBDYyfBUOtIY9606	rogid:eufE+8nfcHK8CDl+AQ5G+3NtL+09606	rigid:N2mLxc11JyPJrBt/iK3wWw2nV0s	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y679	uniprotkb:Q9P265	intact:EBI-1058701|ensembl:ENSP00000366748|uniprotkb:Q9H866|uniprotkb:Q9UNQ6|uniprotkb:Q9Y685|uniprotkb:C0H5W8	intact:EBI-3197808|ensembl:ENSP00000301180|uniprotkb:Q8NB38|uniprotkb:Q6B011|uniprotkb:Q8N1L5	psi-mi:aup1_human(display_long)|uniprotkb:AUP1(gene name)|psi-mi:AUP1(display_short)|uniprotkb:Ancient ubiquitous protein 1(gene name synonym)	psi-mi:dip2b_human(display_long)|uniprotkb:DIP2B(gene name)|psi-mi:DIP2B(display_short)|uniprotkb:KIAA1463(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770979|imex:IM-28143-98	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115307(gene)|ensembl:ENST00000377526(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:NP_853553.1|go:"GO:0034389"(lipid droplet organization)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061724"(lipophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:0140042"(lipid droplet formation)|go:"GO:1990044"(protein localization to lipid droplet)|interpro:IPR003892(Ubiquitin system component Cue)|rcsb pdb:2EKF	ensembl:ENSG00000066084(gene)|ensembl:ENST00000301180(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR010506(DMAP1-binding)|interpro:IPR037337|interpro:IPR042099|refseq:NP_775873.2|genbank_nucl_gi:55749758(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:6yySfIPpRUlnm0upBDYyfBUOtIY9606	rogid:X7jNpAW56irfpaRe6fX95p/ensg9606	rigid:N2mLxc11JyPJrBt/iK3wWw2nV0s	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y679	uniprotkb:P60604	intact:EBI-1058701|ensembl:ENSP00000366748|uniprotkb:Q9H866|uniprotkb:Q9UNQ6|uniprotkb:Q9Y685|uniprotkb:C0H5W8	intact:EBI-1051028|uniprotkb:P56554|uniprotkb:A8K3L4|uniprotkb:D3DSL7|uniprotkb:A6NMQ7|ensembl:ENSP00000338348	psi-mi:aup1_human(display_long)|uniprotkb:AUP1(gene name)|psi-mi:AUP1(display_short)|uniprotkb:Ancient ubiquitous protein 1(gene name synonym)	psi-mi:ub2g2_human(display_long)|uniprotkb:Ubiquitin-protein ligase G2(gene name synonym)|uniprotkb:Ubiquitin carrier protein G2(gene name synonym)|uniprotkb:UBE2G2(gene name)|psi-mi:UBE2G2(display_short)|uniprotkb:E2 ubiquitin-conjugating enzyme G2(gene name synonym)|uniprotkb:UBC7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770979|imex:IM-28143-98	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115307(gene)|ensembl:ENST00000377526(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:NP_853553.1|go:"GO:0034389"(lipid droplet organization)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061724"(lipophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:0140042"(lipid droplet formation)|go:"GO:1990044"(protein localization to lipid droplet)|interpro:IPR003892(Ubiquitin system component Cue)|rcsb pdb:2EKF	refseq:NP_001189418.1|refseq:NP_003334.2|refseq:NP_872630.1|refseq:XP_016883958.1|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2CYX|rcsb pdb:2KLY|rcsb pdb:2LXP|rcsb pdb:3H8K|rcsb pdb:4LAD|reactome:R-HSA-8866652|reactome:R-HSA-983168|ensembl:ENSG00000184787(gene)|ensembl:ENST00000345496(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-50750N|genbank_nucl_gi:33359701(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:6yySfIPpRUlnm0upBDYyfBUOtIY9606	rogid:Q/uslqX/WH/SxKEPYeMmU9CjTBI9606	rigid:N2mLxc11JyPJrBt/iK3wWw2nV0s	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9Y679	uniprotkb:Q6IMN6	intact:EBI-1058701|ensembl:ENSP00000366748|uniprotkb:Q9H866|uniprotkb:Q9UNQ6|uniprotkb:Q9Y685|uniprotkb:C0H5W8	intact:EBI-6918449|uniprotkb:E4NKG2|uniprotkb:Q149P6|uniprotkb:Q149P7|uniprotkb:Q6IMN5|uniprotkb:Q7Z371|uniprotkb:Q8TE70|uniprotkb:Q8TE71|uniprotkb:Q96RN6|uniprotkb:Q9H667|uniprotkb:Q9HAL4	psi-mi:aup1_human(display_long)|uniprotkb:AUP1(gene name)|psi-mi:AUP1(display_short)|uniprotkb:Ancient ubiquitous protein 1(gene name synonym)	psi-mi:capr2_human(display_long)|uniprotkb:CAPRIN2(gene name)|psi-mi:CAPRIN2(display_short)|uniprotkb:C1QDC1(gene name synonym)|uniprotkb:EEG1(gene name synonym)|uniprotkb:KIAA1873(gene name synonym)|uniprotkb:RNG140(gene name synonym)|uniprotkb:C1q domain-containing protein 1(gene name synonym)|uniprotkb:Cytoplasmic activation/proliferation-associated protein 2(gene name synonym)|uniprotkb:Gastric cancer multidrug resistance-associated protein(gene name synonym)|uniprotkb:Protein EEG-1(gene name synonym)|uniprotkb:RNA granule protein 140(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770979|imex:IM-28143-98	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000115307(gene)|ensembl:ENST00000377526(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:NP_853553.1|go:"GO:0034389"(lipid droplet organization)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061724"(lipophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:0140042"(lipid droplet formation)|go:"GO:1990044"(protein localization to lipid droplet)|interpro:IPR003892(Ubiquitin system component Cue)|rcsb pdb:2EKF	rcsb pdb:4OUL|rcsb pdb:4OUM|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0043235"(receptor complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0017148"(negative regulation of translation)|interpro:IPR028816|refseq:NP_001306771.1|refseq:NP_001306772.1|interpro:IPR001073(Complement C1q protein)|interpro:IPR022070|interpro:IPR008983(Tumour necrosis factor-like)|refseq:NP_001002259.1|refseq:NP_001193785.1|refseq:NP_076414.2|refseq:NP_115532.3|refseq:XP_006719210.1|rcsb pdb:5J97|interpro:IPR041637|genbank_nucl_gi:23503235(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:6yySfIPpRUlnm0upBDYyfBUOtIY9606	rogid:doFlseJcb6jzptDJuo58S3EOO309606	rigid:N2mLxc11JyPJrBt/iK3wWw2nV0s	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:Q9GZP9	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-7962814|uniprotkb:Q9Y3A7|intact:MINT-3065126|ensembl:ENSP00000158771	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:derl2_human(display_long)|uniprotkb:DERL2(gene name)|psi-mi:DERL2(display_short)|uniprotkb:DER2(gene name synonym)|uniprotkb:FLANA(gene name synonym)|uniprotkb:CGI-101(orf name)|uniprotkb:SBBI53(orf name)|uniprotkb:Der1-like protein 2(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 2(gene name synonym)|uniprotkb:F-LAN-1(gene name synonym)|uniprotkb:F-LANa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770808|imex:IM-28143-114	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_001291708.1|refseq:NP_057125.2|ensembl:ENSG00000072849(gene)|ensembl:ENST00000158771(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0001967"(suckling behavior)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|genbank_nucl_gi:50400648(identity)	-	-	comment:mint|function:"Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate. In contrast to DERL1, it is not involved in the degradation of MHC class I heavy chains following infection by cytomegaloviruses. May play a role in cell proliferation"	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:hoayS/Xn9+pq/C61NYRu/1aOm6s9606	rigid:HoJhp23F8bxaWswx4D8hkavDfpg	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:Q8NBM4	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770808|imex:IM-28143-114	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1|genbank_nucl_gi:74751173(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rigid:HoJhp23F8bxaWswx4D8hkavDfpg	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:Q9BTV4	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-721293|uniprotkb:Q7L4N5|uniprotkb:Q8NC30|uniprotkb:Q96A63|uniprotkb:Q96F19|uniprotkb:Q96JX0|uniprotkb:Q9H076|ensembl:ENSP00000303992	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:tmm43_human(display_long)|uniprotkb:TMEM43(gene name)|psi-mi:TMEM43(display_short)|uniprotkb:UNQ2564/PRO6244(orf name)|uniprotkb:Protein LUMA(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770808|imex:IM-28143-114	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_077310.1|ensembl:ENSG00000170876(gene)|ensembl:ENST00000306077(transcript)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0071763"(nuclear membrane organization)|interpro:IPR012430(Protein of unknown function DUF1625)|genbank_nucl_gi:74733151(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:8VCyVNtrzh7J9uJ2EjQLBhJGrfc9606	rigid:HoJhp23F8bxaWswx4D8hkavDfpg	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:Q9BSJ8	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-355956|ensembl:ENSP00000377612|uniprotkb:A0FGR7|uniprotkb:A8K2S2|uniprotkb:O94848|uniprotkb:Q6PJN4|uniprotkb:Q9H6J1|uniprotkb:Q9H6W2|uniprotkb:Q9Y416|intact:EBI-4399548	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:esyt1_human(display_long)|uniprotkb:KIAA0747(gene name synonym)|uniprotkb:MBC2(gene name synonym)|uniprotkb:ESYT1(gene name)|psi-mi:ESYT1(display_short)|uniprotkb:Membrane-bound C2 domain-containing protein(gene name synonym)|uniprotkb:FAM62A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770808|imex:IM-28143-114	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	interpro:IPR037752|interpro:IPR039010|mint:Q9BSJ8|reactome:R-HSA-1660662|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9035034|interpro:IPR037749|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037733|go:"GO:0005544"(calcium-dependent phospholipid binding)|ensembl:ENSG00000139641(gene)|ensembl:ENST00000394048(transcript)|go:"GO:0005509"(calcium ion binding)|refseq:NP_001171725.1|refseq:NP_056107.1|dip:DIP-57197N|genbank_nucl_gi:74733019(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:MYbYK3357LLH0TP1qU7CsvJenGk9606	rigid:HoJhp23F8bxaWswx4D8hkavDfpg	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:P40855	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-594747|uniprotkb:Q8NI97|intact:EBI-981972|uniprotkb:Q5QNY4|uniprotkb:D3DVE7|ensembl:ENSP00000357051	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:pex19_human(display_long)|uniprotkb:PEX19(gene name)|psi-mi:PEX19(display_short)|uniprotkb:HK33(gene name synonym)|uniprotkb:PXF(gene name synonym)|uniprotkb:OK/SW-cl.22(orf name)|uniprotkb:Peroxin-19(gene name synonym)|uniprotkb:Peroxisomal farnesylated protein(gene name synonym)|uniprotkb:33 kDa housekeeping protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770808|imex:IM-28143-114	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_001180573.1|refseq:NP_002848.1|dip:DIP-24172N|ensembl:ENSG00000162735(gene)|ensembl:ENST00000368072(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006625"(protein targeting to peroxisome)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016557"(peroxisome membrane biogenesis)|go:"GO:0016559"(peroxisome fission)|go:"GO:0031526"(brush border membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033328"(peroxisome membrane targeting sequence binding)|go:"GO:0036105"(peroxisome membrane class-1 targeting sequence binding)|go:"GO:0045046"(protein import into peroxisome membrane)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0072663"(establishment of protein localization to peroxisome)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:1900131"(negative regulation of lipid binding)|interpro:IPR006708(Pex19 protein)|interpro:IPR038322|mint:P40855|rcsb pdb:2W85|rcsb pdb:2WL8|rcsb pdb:3AJB|rcsb pdb:3MK4|rcsb pdb:5LNF|reactome:R-HSA-1369062|reactome:R-HSA-9603798|genbank_nucl_gi:729723(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:yNnX2hPPJ7miGaz2Req0qFn0L189606	rigid:HoJhp23F8bxaWswx4D8hkavDfpg	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:O75477	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-359299|uniprotkb:B0QZ42|uniprotkb:Q53HV0|ensembl:ENSP00000384900|ensembl:ENSP00000410964|intact:EBI-21351077|uniprotkb:D3DR65	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:erln1_human(display_long)|uniprotkb:KEO4(gene name synonym)|uniprotkb:ERLIN1(gene name)|psi-mi:ERLIN1(display_short)|uniprotkb:C10orf69(gene name synonym)|uniprotkb:KE04(gene name synonym)|uniprotkb:SPFH1(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 1(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1(gene name synonym)|uniprotkb:Protein KE04(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770808|imex:IM-28143-114	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_001094096.1|refseq:NP_006450.2|ensembl:ENSG00000107566(gene)|ensembl:ENST00000407654(transcript)|ensembl:ENST00000421367(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O75477|reactome:R-HSA-382556|reactome:R-HSA-5678895|refseq:NP_001334786.1|refseq:NP_001334788.1|refseq:NP_001334789.1|refseq:NP_001334790.1|genbank_nucl_gi:67461552(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:HycFhL5qL5GLmaIIc9NtTcBbu1M9606	rigid:HoJhp23F8bxaWswx4D8hkavDfpg	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:Q86VP6	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-456077|uniprotkb:O94918|uniprotkb:Q6PIY4|uniprotkb:Q8NDJ4|uniprotkb:Q96JZ9|uniprotkb:Q96T19|uniprotkb:Q9BTC4|uniprotkb:Q9H0G2|uniprotkb:Q9P0H7|uniprotkb:Q9UF85|uniprotkb:B2RAU3|ensembl:ENSP00000442318	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:cand1_human(display_long)|uniprotkb:KIAA0829(gene name synonym)|uniprotkb:TIP120(gene name synonym)|uniprotkb:TIP120A(gene name synonym)|uniprotkb:Cullin-associated and neddylation-dissociated protein 1(gene name synonym)|uniprotkb:p120 CAND1(gene name synonym)|uniprotkb:TBP-interacting protein of 120 kDa A(gene name synonym)|uniprotkb:CAND1(gene name)|psi-mi:CAND1(display_short)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770808|imex:IM-28143-114	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_060918.2|dip:DIP-31608N|ensembl:ENSG00000111530(gene)|ensembl:ENST00000545606(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010265"(SCF complex assembly)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR013932("TATA-binding protein interacting (TIP20)")|interpro:IPR039852|mint:Q86VP6|rcsb pdb:1U6G|rcsb pdb:4A0C|reactome:R-HSA-6798695|reactome:R-HSA-8951664|reactome:R-HSA-917937|interpro:IPR016024(Armadillo-type fold)|genbank_nucl_gi:67460541(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:2lBY8xJXlGZL+xyo/dyB2WzuNqs9606	rigid:HoJhp23F8bxaWswx4D8hkavDfpg	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:O96011	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-594824|uniprotkb:Q96ET2|uniprotkb:B3KN85|uniprotkb:B4DXH9|ensembl:ENSP00000358312	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:px11b_human(display_long)|uniprotkb:Peroxisomal biogenesis factor 11B(gene name synonym)|uniprotkb:Protein PEX11 homolog beta(gene name synonym)|uniprotkb:PEX11B(gene name)|psi-mi:PEX11B(display_short)|uniprotkb:Peroxin-11B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770808|imex:IM-28143-114	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_003837.1|refseq:NP_001171724.1|ensembl:ENSG00000131779(gene)|ensembl:ENST00000369306(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007031"(peroxisome organization)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044375"(regulation of peroxisome size)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|reactome:R-HSA-9603798|genbank_nucl_gi:62901069(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:5/6FYSwT/s0zO+x+5vM73A1sCsA9606	rigid:HoJhp23F8bxaWswx4D8hkavDfpg	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:Q9UBV2	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-358766|uniprotkb:Q6UWT6|uniprotkb:Q9P1T9|uniprotkb:Q9UHK7|ensembl:ENSP00000337053	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:se1l1_human(display_long)|uniprotkb:SEL1L(gene name)|psi-mi:SEL1L(display_short)|uniprotkb:TSA305(gene name synonym)|uniprotkb:UNQ128/PRO1063(orf name)|uniprotkb:Suppressor of lin-12-like protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770808|imex:IM-28143-114	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_001231913.1|refseq:NP_005056.3|ensembl:ENSG00000071537(gene)|ensembl:ENST00000336735(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0050821"(protein stabilization)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|mint:Q9UBV2|reactome:R-HSA-1912420|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-46259N|genbank_nucl_gi:62512184(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:eufE+8nfcHK8CDl+AQ5G+3NtL+09606	rigid:HoJhp23F8bxaWswx4D8hkavDfpg	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:P55060	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-286709|uniprotkb:O75432|uniprotkb:Q32M40|uniprotkb:Q9H5B7|uniprotkb:Q9NTS0|uniprotkb:Q9UP98|uniprotkb:Q9UP99|uniprotkb:Q9UPA0|uniprotkb:B2R5T4|uniprotkb:E1P5Y0|uniprotkb:A3RLL6|uniprotkb:F8W904|ensembl:ENSP00000262982	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:xpo2_human(display_long)|uniprotkb:Importin-alpha re-exporter(gene name synonym)|uniprotkb:Chromosome segregation 1-like protein(gene name synonym)|uniprotkb:Cellular apoptosis susceptibility protein(gene name synonym)|uniprotkb:CSE1L(gene name)|psi-mi:CSE1L(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:XPO2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770808|imex:IM-28143-114	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:XP_011526901.1|refseq:NP_001307.2|refseq:NP_001243064.1|dip:DIP-32573N|ensembl:ENSG00000124207(gene)|ensembl:ENST00000262982(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR005043(CAS/CSE, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:P55060|genbank_nucl_gi:62297557(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:5MlTHLE2eN8Cj5K4xhSt6lCheVs9606	rigid:HoJhp23F8bxaWswx4D8hkavDfpg	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:P55072	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770808|imex:IM-28143-114	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N|genbank_nucl_gi:6094447(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606	rigid:HoJhp23F8bxaWswx4D8hkavDfpg	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:Q71U36	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770808|imex:IM-28143-114	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|genbank_nucl_gi:55977864(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606	rigid:HoJhp23F8bxaWswx4D8hkavDfpg	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:Q92616	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-356221|ensembl:ENSP00000300648|uniprotkb:O95001|uniprotkb:O95651|uniprotkb:Q6P2S3|uniprotkb:Q86X65|uniprotkb:Q8N5I5|uniprotkb:Q8WU80|uniprotkb:Q99736|uniprotkb:Q9UE60|uniprotkb:A8KAY1|intact:EBI-1058692	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:gcn1_human(display_long)|uniprotkb:GCN1(gene name)|psi-mi:GCN1(display_short)|uniprotkb:GCN1 eIF-2-alpha kinase activator homolog(gene name synonym)|uniprotkb:GCN1-like protein 1(gene name synonym)|uniprotkb:GCN1L1(gene name synonym)|uniprotkb:General control of amino-acid synthesis 1-like protein 1(gene name synonym)|uniprotkb:KIAA0219(gene name synonym)|uniprotkb:Translational activator GCN1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770808|imex:IM-28143-114	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	ensembl:ENSG00000089154(gene)|ensembl:ENST00000300648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0043022"(ribosome binding)|go:"GO:0045296"(cadherin binding)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR033173|interpro:IPR034085|mint:Q92616|reactome:R-HSA-9633012|go:"GO:0005844"(polysome)|refseq:NP_006827.1|genbank_nucl_gi:54607053(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:NtSEW6xjvCkUyb40cnk0JdL5PcA9606	rigid:HoJhp23F8bxaWswx4D8hkavDfpg	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:P55786	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-1046129|uniprotkb:Q6P145|uniprotkb:Q9NP16|uniprotkb:Q9UEM2|ensembl:ENSP00000320324|ensembl:ENSP00000503682|uniprotkb:B7Z463	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:psa_human(display_long)|uniprotkb:NPEPPS(gene name)|psi-mi:NPEPPS(display_short)|uniprotkb:PSA(gene name synonym)|uniprotkb:Cytosol alanyl aminopeptidase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770808|imex:IM-28143-114	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_006301.3|ensembl:ENSG00000141279(gene)|ensembl:ENST00000322157(transcript)|ensembl:ENST00000677120(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042277"(peptide binding)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR024571|interpro:IPR027268|interpro:IPR034016|interpro:IPR042097|reactome:R-HSA-983168|refseq:NP_001317186.1|genbank_nucl_gi:51704228(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:gDl9SPlJhCOhA8uF4OEw+lIPh2M9606	rigid:HoJhp23F8bxaWswx4D8hkavDfpg	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:P84085	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-4289908|uniprotkb:P26437|ensembl:ENSP00000000233	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:arf5_human(display_long)|uniprotkb:ARF5(gene name)|psi-mi:ARF5(display_short)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770808|imex:IM-28143-114	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	ensembl:ENSG00000004059(gene)|ensembl:ENST00000000233(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P84085|rcsb pdb:2B6H|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:NP_001653.1|dip:DIP-61289N|genbank_nucl_gi:51316990(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:da8exbGR3MGxZ6CPZqLvqJbyUYI9606	rigid:HoJhp23F8bxaWswx4D8hkavDfpg	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:Q9BUN8	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-398977|uniprotkb:B3KW41|uniprotkb:E9PH19|ensembl:ENSP00000259512	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:derl1_human(display_long)|uniprotkb:DERL1(gene name)|psi-mi:DERL1(display_short)|uniprotkb:UNQ243/PRO276(orf name)|uniprotkb:Der1-like protein 1(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:DER1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770808|imex:IM-28143-114	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_001128143.1|refseq:NP_077271.1|ensembl:ENSG00000136986(gene)|ensembl:ENST00000259512(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002020"(protease binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0036502"(Derlin-1-VIMP complex)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|rcsb pdb:5GLF|rcsb pdb:7CZB|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5678895|reactome:R-HSA-8866654|genbank_nucl_gi:50400630(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:M35Ah+CuYuV7RP1edsda6vU7Bgo9606	rigid:HoJhp23F8bxaWswx4D8hkavDfpg	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:P17858	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-487243|uniprotkb:Q96A64|uniprotkb:Q96IH4|uniprotkb:Q9BR91|ensembl:ENSP00000269848	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:pfkal_human(display_long)|uniprotkb:PFKL(gene name)|psi-mi:PFKL(display_short)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:Phosphofructo-1-kinase isozyme B(gene name synonym)|uniprotkb:6-phosphofructokinase type B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770808|imex:IM-28143-114	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_001002021.2|refseq:NP_002617.3|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0009749"(response to glucose)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070095"(fructose-6-phosphate binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070061"(fructose binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000023(Phosphofructokinase)|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR022953|interpro:IPR035966|interpro:IPR041914|mint:P17858|reactome:R-HSA-6798695|reactome:R-HSA-70171|ensembl:ENSG00000141959(gene)|ensembl:ENST00000349048(transcript)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005945"(6-phosphofructokinase complex)|genbank_nucl_gi:48762920(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:lP9/V5WcCl5rLpy4QEZnWkLCCcQ9606	rigid:HoJhp23F8bxaWswx4D8hkavDfpg	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:Q9P2J5	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-356077|uniprotkb:Q9NSE1|uniprotkb:A2RRR4|uniprotkb:B4DJ10|uniprotkb:Q2TU79|uniprotkb:A7E266|ensembl:ENSP00000377954	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:sylc_human(display_long)|uniprotkb:LARS1(gene name)|psi-mi:LARS1(display_short)|uniprotkb:KIAA1352(gene name synonym)|uniprotkb:LARS(gene name synonym)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770808|imex:IM-28143-114	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_064502.9|refseq:NP_001304893.1|refseq:NP_001304894.1|refseq:NP_057544.2|refseq:XP_011535958.1|ensembl:ENSG00000133706(gene)|ensembl:ENST00000394434(transcript)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004819"(glutamine-tRNA ligase activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006425"(glutaminyl-tRNA aminoacylation)|go:"GO:0006429"(leucyl-tRNA aminoacylation)|go:"GO:0008361"(regulation of cell size)|go:"GO:0012505"(endomembrane system)|go:"GO:0016604"(nuclear body)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071233"(cellular response to leucine)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR004493(Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|mint:Q9P2J5|rcsb pdb:2WFD|rcsb pdb:6KID|rcsb pdb:6KIE|rcsb pdb:6KQY|rcsb pdb:6KR7|rcsb pdb:6LPF|rcsb pdb:6LR6|reactome:R-HSA-2408522|reactome:R-HSA-379716|genbank_nucl_gi:48428689(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:nlK4kRCik2LLC3VNl0sryrLLnqA9606	rigid:HoJhp23F8bxaWswx4D8hkavDfpg	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:Q9UBE0	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-743154|ensembl:ENSP00000270225|uniprotkb:O95717|uniprotkb:Q9P020|uniprotkb:B2RDP5|uniprotkb:B3KMQ2|uniprotkb:F5GXX7|uniprotkb:G3XAK6	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:sae1_human(display_long)|uniprotkb:Ubiquitin-like 1-activating enzyme E1A(gene name synonym)|uniprotkb:SAE1(gene name)|psi-mi:SAE1(display_short)|uniprotkb:AOS1(gene name synonym)|uniprotkb:UBLE1A(gene name synonym)|uniprotkb:SUA1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770808|imex:IM-28143-114	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	ensembl:ENSG00000142230(gene)|ensembl:ENST00000270225(transcript)|go:"GO:0004839"(ubiquitin activating enzyme activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0031510"(SUMO activating enzyme complex)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000011(Ubiquitin-activating enzyme, E1)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR035985|mint:Q9UBE0|rcsb pdb:1Y8Q|rcsb pdb:1Y8R|rcsb pdb:3KYC|rcsb pdb:3KYD|rcsb pdb:6CWY|rcsb pdb:6CWZ|rcsb pdb:6XOG|rcsb pdb:6XOH|rcsb pdb:6XOI|reactome:R-HSA-3065676|reactome:R-HSA-3065678|refseq:NP_005491.1|refseq:NP_001139185.1|refseq:NP_001139186.1|dip:DIP-34587N|genbank_nucl_gi:42559897(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:8Az5p8NJ5XfF1pxbyynnYrQLFN89606	rigid:HoJhp23F8bxaWswx4D8hkavDfpg	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:P49736	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-374819|uniprotkb:Q14577|uniprotkb:Q15023|uniprotkb:Q8N2V1|uniprotkb:Q969W7|uniprotkb:Q96AE1|uniprotkb:Q9BRM7|ensembl:ENSP00000265056	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:mcm2_human(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:BM28(gene name synonym)|uniprotkb:CDCL1(gene name synonym)|uniprotkb:KIAA0030(gene name synonym)|uniprotkb:Minichromosome maintenance protein 2 homolog(gene name synonym)|uniprotkb:Nuclear protein BM28(gene name synonym)|uniprotkb:CCNL1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770808|imex:IM-28143-114	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	ensembl:ENSG00000073111(gene)|ensembl:ENST00000265056(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006915"(apoptotic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0042393"(histone binding)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090102"(cochlea development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P49736|rcsb pdb:4UUZ|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5JA4|rcsb pdb:6XTX|rcsb pdb:6XTY|rcsb pdb:6YA7|rcsb pdb:7CIZ|rcsb pdb:7CJ0|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|refseq:NP_004517.2|dip:DIP-31732N|genbank_nucl_gi:41019490(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:Jt9ODNyJBwtwQ0pb/+X46vtHfE09606	rigid:HoJhp23F8bxaWswx4D8hkavDfpg	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:Q9BVK6	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-1056827|uniprotkb:Q8WZ61|uniprotkb:Q14437|ensembl:ENSP00000330945	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:tmed9_human(display_long)|uniprotkb:TMED9(gene name)|psi-mi:TMED9(display_short)|uniprotkb:GP25L2(gene name synonym)|uniprotkb:Glycoprotein 25L2(gene name synonym)|uniprotkb:p25(gene name synonym)|uniprotkb:p24 family protein alpha-2(gene name synonym)|uniprotkb:GMP25(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770808|imex:IM-28143-114	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_059980.2|ensembl:ENSG00000184840(gene)|ensembl:ENST00000332598(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|mint:Q9BVK6|reactome:R-HSA-6807878|reactome:R-HSA-6811434|genbank_nucl_gi:39725636(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:z5YDyY6mtnc4WGWU9G9sNgp+Ga09606	rigid:HoJhp23F8bxaWswx4D8hkavDfpg	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:O94905	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-4400770|uniprotkb:A0JLQ1|uniprotkb:A8K5S9|uniprotkb:B4DM38|uniprotkb:D3DSW0|uniprotkb:Q6NW21|uniprotkb:Q86VS6|uniprotkb:Q86W49|ensembl:ENSP00000428112	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:erln2_human(display_long)|uniprotkb:ERLIN2(gene name)|psi-mi:ERLIN2(display_short)|uniprotkb:C8orf2(gene name synonym)|uniprotkb:SPFH2(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 2(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2(gene name synonym)|uniprotkb:UNQ2441/PRO5003/PRO9924(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770808|imex:IM-28143-114	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_001003790.1|refseq:NP_001003791.1|refseq:NP_009106.1|refseq:XP_016868489.1|refseq:XP_005273449.1|ensembl:ENSG00000147475(gene)|ensembl:ENST00000519638(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045121"(membrane raft)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O94905|reactome:R-HSA-382556|reactome:R-HSA-5655302|reactome:R-HSA-5678895|reactome:R-HSA-8853336|genbank_nucl_gi:38257366(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:Evjg3G0FFeQ499BNlJxpK6t8to89606	rigid:HoJhp23F8bxaWswx4D8hkavDfpg	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:Q9BQE4	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-398970|uniprotkb:Q3B771|uniprotkb:Q9P0I6|ensembl:ENSP00000381282|ensembl:ENSP00000433541	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:sels_human(display_long)|uniprotkb:SELENOS(gene name)|psi-mi:SELENOS(display_short)|uniprotkb:SELS(gene name synonym)|uniprotkb:VCP-interacting membrane protein(gene name synonym)|uniprotkb:VIMP(gene name synonym)|uniprotkb:AD-015(orf name)|uniprotkb:SBBI8(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770808|imex:IM-28143-114	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_060915.2|refseq:NP_982298.2|ensembl:ENSG00000131871(gene)|ensembl:ENST00000398226(transcript)|ensembl:ENST00000526049(transcript)|go:"GO:0002865"(negative regulation of acute inflammatory response to antigenic stimulus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006983"(ER overload response)|go:"GO:0009749"(response to glucose)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036502"(Derlin-1-VIMP complex)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051117"(ATPase binding)|go:"GO:0051775"(response to redox state)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080164"(regulation of nitric oxide metabolic process)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR009703(Selenoprotein S)|rcsb pdb:2Q2F|rcsb pdb:5KIU|rcsb pdb:5KIY|rcsb pdb:6DO4|reactome:R-HSA-8866654|go:"GO:0051771"(negative regulation of nitric-oxide synthase biosynthetic process)|genbank_nucl_gi:33285002(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:bg+Gf++/TqIgpUErI5PgcLomcCQ9606	rigid:HoJhp23F8bxaWswx4D8hkavDfpg	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:Q13438	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-725454|intact:EBI-1174342|uniprotkb:A6NDD1|uniprotkb:A6NFR7|uniprotkb:A6NLB2|uniprotkb:A8K5Q9|uniprotkb:B4DPX1|uniprotkb:B4E1I6|uniprotkb:E7ENT8|uniprotkb:F8VUH2|uniprotkb:O00579|uniprotkb:Q6IBL2|uniprotkb:Q8IZ58|uniprotkb:Q9BW99|uniprotkb:B4DE28|ensembl:ENSP00000318165|uniprotkb:E7EW91|uniprotkb:G3XA88	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:os9_human(display_long)|uniprotkb:OS9(gene name)|psi-mi:OS9(display_short)|uniprotkb:Amplified in osteosarcoma 9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770808|imex:IM-28143-114	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_006803.1|refseq:NP_001017956.1|refseq:NP_001017957.1|refseq:NP_001017958.1|refseq:NP_001248349.1|refseq:NP_001248350.1|refseq:NP_001248351.1|refseq:NP_001248352.1|ensembl:ENSG00000135506(gene)|ensembl:ENST00000315970(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0002020"(protease binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006605"(protein targeting)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|interpro:IPR044865|rcsb pdb:3AIH|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-37493N|genbank_nucl_gi:3024310(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:Ntc3geE7th+rBeIp0MxuUuu/28Y9606	rigid:HoJhp23F8bxaWswx4D8hkavDfpg	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:Q15388	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-711636|uniprotkb:A8K195|uniprotkb:Q498B3|uniprotkb:Q6IBT4|ensembl:ENSP00000355566	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:tom20_human(display_long)|uniprotkb:Outer mitochondrial membrane receptor Tom20(gene name synonym)|uniprotkb:TOMM20(gene name)|psi-mi:TOMM20(display_short)|uniprotkb:KIAA0016(gene name synonym)|uniprotkb:Mitochondrial 20 kDa outer membrane protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770808|imex:IM-28143-114	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_055580.1|dip:DIP-46735N|ensembl:ENSG00000173726(gene)|ensembl:ENST00000366607(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016031"(tRNA import into mitochondrion)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0030943"(mitochondrion targeting sequence binding)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1905242"(response to 3,3',5-triiodo-L-thyronine)|interpro:IPR002056(Protein import receptor MAS20)|interpro:IPR022422|interpro:IPR023392|rcsb pdb:4APO|reactome:R-HSA-1268020|reactome:R-HSA-5205685|reactome:R-HSA-5689880|genbank_nucl_gi:2498697(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:+wNh1qTU0NtgQekYJjhfj6O3UoA9606	rigid:HoJhp23F8bxaWswx4D8hkavDfpg	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:O95292	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-1188298|uniprotkb:O95293|uniprotkb:Q9P0H0|uniprotkb:A2A2F2|ensembl:ENSP00000417175	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:vapb_human(display_long)|uniprotkb:VAPB(gene name)|psi-mi:VAPB(display_short)|uniprotkb:UNQ484/PRO983(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770808|imex:IM-28143-114	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_001182606.1|refseq:NP_004729.1|ensembl:ENSG00000124164(gene)|ensembl:ENST00000475243(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044790"(suppression of viral release by host)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:O95292|rcsb pdb:2MDK|rcsb pdb:3IKK|reactome:R-HSA-1660661|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|dip:DIP-39816N|genbank_nucl_gi:24638339(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:+TuApjAmnGF1UZonXIsrPaIN4Ak9606	rigid:HoJhp23F8bxaWswx4D8hkavDfpg	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:Q9NS69	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-1047508|intact:EBI-1180569|ensembl:ENSP00000216034	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:tom22_human(display_long)|uniprotkb:TOMM22(gene name)|psi-mi:TOMM22(display_short)|uniprotkb:TOM22(gene name synonym)|uniprotkb:Translocase of outer membrane 22 kDa subunit homolog(gene name synonym)|uniprotkb:1C9-2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770808|imex:IM-28143-114	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_064628.1|ensembl:ENSG00000100216(gene)|ensembl:ENST00000216034(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|interpro:IPR005683(Mitochondrial import translocase, subunit Tom22)|mint:Q9NS69|rcsb pdb:7CK6|rcsb pdb:7CP9|reactome:R-HSA-1268020|reactome:R-HSA-5205685|genbank_nucl_gi:24212074(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:DI3BGFSB04B1/mMHJsBpOsCxrYk9606	rigid:HoJhp23F8bxaWswx4D8hkavDfpg	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:P51149	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-1056089|uniprotkb:A8K3V6|uniprotkb:Q9NWJ0|uniprotkb:Q9UPB0|ensembl:ENSP00000265062|ensembl:ENSP00000501618|ensembl:ENSP00000502000|ensembl:ENSP00000502088|ensembl:ENSP00000502486	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:rab7a_human(display_long)|uniprotkb:RAB7A(gene name)|psi-mi:RAB7A(display_short)|uniprotkb:RAB7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770808|imex:IM-28143-114	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_004628.4|ensembl:ENSG00000075785(gene)|ensembl:ENST00000265062(transcript)|ensembl:ENST00000674589(transcript)|ensembl:ENST00000675342(transcript)|ensembl:ENST00000675497(transcript)|ensembl:ENST00000676214(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006897"(endocytosis)|go:"GO:0007174"(epidermal growth factor catabolic process)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0019003"(GDP binding)|go:"GO:0019076"(viral release from host cell)|go:"GO:0022615"(protein to membrane docking)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032419"(extrinsic component of lysosome membrane)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0061724"(lipophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090382"(phagosome maturation)|go:"GO:0090383"(phagosome acidification)|go:"GO:0090385"(phagosome-lysosome fusion)|go:"GO:0099638"(endosome to plasma membrane protein transport)|go:"GO:1902586"(obsolete multi-organism intercellular transport)|go:"GO:1903542"(negative regulation of exosomal secretion)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1905366"(negative regulation of intralumenal vesicle formation)|go:"GO:1905394"(retromer complex binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51149|rcsb pdb:1T91|rcsb pdb:1YHN|rcsb pdb:6IYB|rcsb pdb:6WCW|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9636383|reactome:R-HSA-9636569|rcsb pdb:3LAW|dip:DIP-39879N|genbank_nucl_gi:1709999(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:AJbKizzw4zCAn+roRF2Im1Tt4xE9606	rigid:HoJhp23F8bxaWswx4D8hkavDfpg	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:Q15041	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-714543|ensembl:ENSP00000306788|uniprotkb:B7Z6S5|uniprotkb:B7Z791|uniprotkb:F5GXP4	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:ar6p1_human(display_long)|uniprotkb:ARL6IP(gene name synonym)|uniprotkb:ARL6IP1(gene name)|psi-mi:ARL6IP1(display_short)|uniprotkb:KIAA0069(gene name synonym)|uniprotkb:ARMER(gene name synonym)|uniprotkb:Apoptotic regulator in the membrane of the endoplasmic reticulum(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770808|imex:IM-28143-114	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_055976.1|ensembl:ENSG00000170540(gene)|ensembl:ENST00000304414(transcript)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1903371"(regulation of endoplasmic reticulum tubular network organization)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR033301|mint:Q15041|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|refseq:NP_001300787.1|genbank_nucl_gi:14424435(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:3fjkoyvUx25po7xsPcXgpjEeLJg9606	rigid:HoJhp23F8bxaWswx4D8hkavDfpg	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:Q01813	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-359022|uniprotkb:B3KS15|uniprotkb:Q5VSR7|uniprotkb:Q5VSR8|ensembl:ENSP00000370517	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:pfkap_human(display_long)|uniprotkb:PFKP(gene name)|psi-mi:PFKP(display_short)|uniprotkb:PFKF(gene name synonym)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:Phosphofructo-1-kinase isozyme C(gene name synonym)|uniprotkb:6-phosphofructokinase type C(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770808|imex:IM-28143-114	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_002618.1|ensembl:ENSG00000067057(gene)|ensembl:ENST00000381125(transcript)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005945"(6-phosphofructokinase complex)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070095"(fructose-6-phosphate binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000023(Phosphofructokinase)|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR022953|interpro:IPR035966|interpro:IPR041914|mint:Q01813|rcsb pdb:4RH3|rcsb pdb:4U1R|rcsb pdb:4WL0|rcsb pdb:4XYJ|rcsb pdb:4XYK|rcsb pdb:4XZ2|reactome:R-HSA-70171|refseq:NP_001229268.1|dip:DIP-45850N|genbank_nucl_gi:1346355(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:GNmWbFrQsTMRdVphWG+3DK3wxaA9606	rigid:HoJhp23F8bxaWswx4D8hkavDfpg	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:P28288	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-80992|ensembl:ENSP00000359233|uniprotkb:Q15271|uniprotkb:Q9H529|uniprotkb:Q6NUN5|uniprotkb:Q96DA3|uniprotkb:D3DT46	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:abcd3_human(display_long)|uniprotkb:ABCD3(gene name)|psi-mi:ABCD3(display_short)|uniprotkb:PMP70(gene name synonym)|uniprotkb:PXMP1(gene name synonym)|uniprotkb:70 kDa peroxisomal membrane protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770808|imex:IM-28143-114	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	ensembl:ENSG00000117528(gene)|ensembl:ENST00000370214(transcript)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0007031"(peroxisome organization)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015910"(long-chain fatty acid import into peroxisome)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042493"|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|refseq:NP_001116146.1|refseq:NP_002849.1|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005283(Peroxysomal long chain fatty acyl transporter)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR036640|mint:P28288|reactome:R-HSA-1369062|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9603798|genbank_nucl_gi:130358(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:aUTR1BDihIx1JxtsC5V4vmFAwA49606	rigid:HoJhp23F8bxaWswx4D8hkavDfpg	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:P04181	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-721662|uniprotkb:Q68CS0|uniprotkb:Q16068|uniprotkb:Q16069|uniprotkb:Q9UD03|intact:EBI-1237002|uniprotkb:Q6IAV9|uniprotkb:D3DRF0|ensembl:ENSP00000357838	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:oat_human(display_long)|uniprotkb:Ornithine--oxo-acid aminotransferase(gene name synonym)|uniprotkb:OAT(gene name)|psi-mi:OAT(display_short)|uniprotkb:Ornithine delta-aminotransferase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770808|imex:IM-28143-114	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_000265.1|refseq:NP_001165285.1|refseq:NP_001309894.1|refseq:NP_001309895.1|refseq:NP_001309896.1|refseq:NP_001309897.1|refseq:NP_001309898.1|refseq:NP_001309899.1|refseq:NP_001309900.1|rcsb pdb:6OIA|rcsb pdb:6V8C|rcsb pdb:6V8D|rcsb pdb:7JX9|reactome:R-HSA-8964539|ensembl:ENSG00000065154(gene)|ensembl:ENST00000368845(transcript)|go:"GO:0004587"(ornithine-oxo-acid transaminase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007601"(visual perception)|go:"GO:0010121"(arginine catabolic process to proline via ornithine)|go:"GO:0019544"(arginine catabolic process to glutamate)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0050155"("ornithine(lysine) transaminase activity")|go:"GO:0055129"(L-proline biosynthetic process)|interpro:IPR005814(Aminotransferase class-III)|interpro:IPR010164(Ornithine aminotransferase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|rcsb pdb:1GBN|rcsb pdb:1OAT|rcsb pdb:2BYJ|rcsb pdb:2BYL|rcsb pdb:2CAN|rcsb pdb:2OAT|rcsb pdb:5VWO|rcsb pdb:6HX7|genbank_nucl_gi:129018(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:j+e5fOgz5Yv7lLp2NV8Uq+eR6909606	rigid:HoJhp23F8bxaWswx4D8hkavDfpg	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:Q9Y277	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-354196|uniprotkb:Q9UIS0|ensembl:ENSP00000022615	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:vdac3_human(display_long)|uniprotkb:VDAC3(gene name)|psi-mi:VDAC3(display_short)|uniprotkb:Outer mitochondrial membrane protein porin 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770808|imex:IM-28143-114	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_001129166.1|refseq:NP_005653.3|ensembl:ENSG00000078668(gene)|ensembl:ENST00000022615(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015853"(adenine transport)|go:"GO:0016020"(membrane)|go:"GO:0046930"(pore complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902017"(regulation of cilium assembly)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030271|mint:Q9Y277|reactome:R-HSA-5689880|reactome:R-HSA-8949215|genbank_nucl_gi:12643945(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:En6g89Dp+C4s1ArGYJyVfUBVsO09606	rigid:HoJhp23F8bxaWswx4D8hkavDfpg	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:O96008	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-1057581|uniprotkb:Q86VW4|uniprotkb:Q8WY09|uniprotkb:Q8WY10|uniprotkb:Q8WY11|uniprotkb:Q9BR95|uniprotkb:A0A024R0P9|ensembl:ENSP00000252487|ensembl:ENSP00000385184|ensembl:ENSP00000410339	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:tom40_human(display_long)|uniprotkb:TOMM40(gene name)|psi-mi:TOMM40(display_short)|uniprotkb:PEREC1(gene name synonym)|uniprotkb:TOM40(gene name synonym)|uniprotkb:C19orf1(gene name synonym)|uniprotkb:Translocase of outer membrane 40 kDa subunit homolog(gene name synonym)|uniprotkb:Protein Haymaker(gene name synonym)|uniprotkb:p38.5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770808|imex:IM-28143-114	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_001122388.1|refseq:NP_001122389.1|refseq:NP_006105.1|ensembl:ENSG00000130204(gene)|ensembl:ENST00000252487(transcript)|ensembl:ENST00000405636(transcript)|ensembl:ENST00000426677(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006811"(ion transport)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015288"(porin activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0046930"(pore complex)|interpro:IPR023614|interpro:IPR027246|interpro:IPR037930|rcsb pdb:7CK6|rcsb pdb:7CP9|reactome:R-HSA-1268020|reactome:R-HSA-5205685|go:"GO:0005741"(mitochondrial outer membrane)|genbank_nucl_gi:12230369(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:BBV//Cb2ekmDNGHNrZuAXRgS++Y9606	rigid:HoJhp23F8bxaWswx4D8hkavDfpg	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96CS3	uniprotkb:P06733	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25770808|imex:IM-28143-114	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|genbank_nucl_gi:119339(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	rigid:HoJhp23F8bxaWswx4D8hkavDfpg	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9P2K2	uniprotkb:P29966	intact:EBI-11126467|uniprotkb:Q9H9W7|uniprotkb:A7E260|uniprotkb:A7MD07|uniprotkb:B9EH67|uniprotkb:A5PKW9|ensembl:ENSP00000281741	intact:EBI-1047781|uniprotkb:E1P560|uniprotkb:Q2LA83|uniprotkb:Q5TDB7|ensembl:ENSP00000478061	psi-mi:txd16_human(display_long)|uniprotkb:TXNDC16(gene name)|psi-mi:TXNDC16(display_short)|uniprotkb:KIAA1344(gene name synonym)|uniprotkb:ERP90(gene name synonym)	psi-mi:marcs_human(display_long)|uniprotkb:Protein kinase C substrate, 80 kDa protein, light chain(gene name synonym)|uniprotkb:MARCKS(gene name)|psi-mi:MARCKS(display_short)|uniprotkb:MACS(gene name synonym)|uniprotkb:PRKCSL(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771267|imex:IM-28143-86	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153519.1|refseq:NP_065835.2|ensembl:ENSG00000087301(gene)|ensembl:ENST00000281741(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR040090	refseq:NP_002347.5|ensembl:ENSG00000277443(gene)|ensembl:ENST00000612661(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007417"(central nervous system development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032432"(actin filament bundle)|go:"GO:0042585"(germinal vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002101(Myristoylated alanine-rich C-kinase substrate MARCKS)|mint:P29966|reactome:R-HSA-399997|genbank_nucl_gi:76803798(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:zzfV8NEefGI6L0ra5Z/bEg3WfEU9606	rogid:28v6sOqwULr0AvfJr7yAal9Yh1g9606	rigid:hhHVBRAkxdDgE5iPNo38wi8ZMFw	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9P2K2	uniprotkb:Q8IWF2	intact:EBI-11126467|uniprotkb:Q9H9W7|uniprotkb:A7E260|uniprotkb:A7MD07|uniprotkb:B9EH67|uniprotkb:A5PKW9|ensembl:ENSP00000281741	intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401	psi-mi:txd16_human(display_long)|uniprotkb:TXNDC16(gene name)|psi-mi:TXNDC16(display_short)|uniprotkb:KIAA1344(gene name synonym)|uniprotkb:ERP90(gene name synonym)	psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771267|imex:IM-28143-86	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153519.1|refseq:NP_065835.2|ensembl:ENSG00000087301(gene)|ensembl:ENST00000281741(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR040090	refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N|genbank_nucl_gi:74759632(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:zzfV8NEefGI6L0ra5Z/bEg3WfEU9606	rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606	rigid:hhHVBRAkxdDgE5iPNo38wi8ZMFw	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9P2K2	uniprotkb:P37802	intact:EBI-11126467|uniprotkb:Q9H9W7|uniprotkb:A7E260|uniprotkb:A7MD07|uniprotkb:B9EH67|uniprotkb:A5PKW9|ensembl:ENSP00000281741	intact:EBI-1056740|intact:EBI-2825986|uniprotkb:Q5JRQ6|uniprotkb:Q5JRQ7|uniprotkb:Q9BUH5|uniprotkb:Q9H4P0|uniprotkb:Q6FGI1|uniprotkb:E9KL39|ensembl:ENSP00000357075|ensembl:ENSP00000357077	psi-mi:txd16_human(display_long)|uniprotkb:TXNDC16(gene name)|psi-mi:TXNDC16(display_short)|uniprotkb:KIAA1344(gene name synonym)|uniprotkb:ERP90(gene name synonym)	psi-mi:tagl2_human(display_long)|uniprotkb:TAGLN2(gene name)|psi-mi:TAGLN2(display_short)|uniprotkb:KIAA0120(gene name synonym)|uniprotkb:SM22-alpha homolog(gene name synonym)|uniprotkb:CDABP0035(orf name)|uniprotkb:Epididymis tissue protein Li 7e(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771267|imex:IM-28143-86	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153519.1|refseq:NP_065835.2|ensembl:ENSG00000087301(gene)|ensembl:ENST00000281741(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR040090	refseq:NP_003555.1|refseq:NP_001264152.1|refseq:NP_001264153.1|ensembl:ENSG00000158710(gene)|ensembl:ENST00000320307(transcript)|ensembl:ENST00000368097(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031982"(vesicle)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000557(Calponin repeat)|interpro:IPR001061("Transgelin (SM22-alpha)")|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR036872|mint:P37802|rcsb pdb:1WYM|reactome:R-HSA-114608|genbank_nucl_gi:586000(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:zzfV8NEefGI6L0ra5Z/bEg3WfEU9606	rogid:JxbMK5SbZWQd+XA9iYc/xuNaVQc9606	rigid:hhHVBRAkxdDgE5iPNo38wi8ZMFw	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9P2K2	uniprotkb:P49736	intact:EBI-11126467|uniprotkb:Q9H9W7|uniprotkb:A7E260|uniprotkb:A7MD07|uniprotkb:B9EH67|uniprotkb:A5PKW9|ensembl:ENSP00000281741	intact:EBI-374819|uniprotkb:Q14577|uniprotkb:Q15023|uniprotkb:Q8N2V1|uniprotkb:Q969W7|uniprotkb:Q96AE1|uniprotkb:Q9BRM7|ensembl:ENSP00000265056	psi-mi:txd16_human(display_long)|uniprotkb:TXNDC16(gene name)|psi-mi:TXNDC16(display_short)|uniprotkb:KIAA1344(gene name synonym)|uniprotkb:ERP90(gene name synonym)	psi-mi:mcm2_human(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:BM28(gene name synonym)|uniprotkb:CDCL1(gene name synonym)|uniprotkb:KIAA0030(gene name synonym)|uniprotkb:Minichromosome maintenance protein 2 homolog(gene name synonym)|uniprotkb:Nuclear protein BM28(gene name synonym)|uniprotkb:CCNL1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771267|imex:IM-28143-86	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153519.1|refseq:NP_065835.2|ensembl:ENSG00000087301(gene)|ensembl:ENST00000281741(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR040090	ensembl:ENSG00000073111(gene)|ensembl:ENST00000265056(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006915"(apoptotic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0042393"(histone binding)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090102"(cochlea development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P49736|rcsb pdb:4UUZ|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5JA4|rcsb pdb:6XTX|rcsb pdb:6XTY|rcsb pdb:6YA7|rcsb pdb:7CIZ|rcsb pdb:7CJ0|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|refseq:NP_004517.2|dip:DIP-31732N|genbank_nucl_gi:41019490(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:zzfV8NEefGI6L0ra5Z/bEg3WfEU9606	rogid:Jt9ODNyJBwtwQ0pb/+X46vtHfE09606	rigid:hhHVBRAkxdDgE5iPNo38wi8ZMFw	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9P2K2	uniprotkb:P24539	intact:EBI-11126467|uniprotkb:Q9H9W7|uniprotkb:A7E260|uniprotkb:A7MD07|uniprotkb:B9EH67|uniprotkb:A5PKW9|ensembl:ENSP00000281741	intact:EBI-1044810|uniprotkb:Q9BQ68|uniprotkb:Q9BRU8|ensembl:ENSP00000358737	psi-mi:txd16_human(display_long)|uniprotkb:TXNDC16(gene name)|psi-mi:TXNDC16(display_short)|uniprotkb:KIAA1344(gene name synonym)|uniprotkb:ERP90(gene name synonym)	psi-mi:at5f1_human(display_long)|uniprotkb:ATP5PB(gene name)|psi-mi:ATP5PB(display_short)|uniprotkb:ATP synthase peripheral stalk-membrane subunit b(gene name synonym)|uniprotkb:"ATP synthase proton-transporting mitochondrial F(0) complex subunit B1"(gene name synonym)|uniprotkb:ATP synthase subunit b(gene name synonym)|uniprotkb:ATP5F1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771267|imex:IM-28143-86	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153519.1|refseq:NP_065835.2|ensembl:ENSG00000087301(gene)|ensembl:ENST00000281741(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR040090	refseq:NP_001679.2|ensembl:ENSG00000116459(gene)|ensembl:ENST00000369722(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0021762"(substantia nigra development)|interpro:IPR008688(ATPase, F0 complex, subunit B, mitochondrial)|interpro:IPR013837(ATPase, F0 complex subunit B, mitochondrial, metazoa)|mint:P24539|reactome:R-HSA-163210|reactome:R-HSA-8949613|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|genbank_nucl_gi:20455474(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:zzfV8NEefGI6L0ra5Z/bEg3WfEU9606	rogid:n1HuorsLzONcID7ccOL9qEsODLE9606	rigid:hhHVBRAkxdDgE5iPNo38wi8ZMFw	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9P2K2	uniprotkb:P22626	intact:EBI-11126467|uniprotkb:Q9H9W7|uniprotkb:A7E260|uniprotkb:A7MD07|uniprotkb:B9EH67|uniprotkb:A5PKW9|ensembl:ENSP00000281741	intact:EBI-299649|ensembl:ENSP00000346694|ensembl:ENSP00000349101|ensembl:ENSP00000354021|ensembl:ENSP00000503360|ensembl:ENSP00000503476|ensembl:ENSP00000503514|ensembl:ENSP00000503885|ensembl:ENSP00000504329|uniprotkb:P22627|uniprotkb:A8K064|uniprotkb:Q9UC98|uniprotkb:Q9UDJ2|uniprotkb:A0A024RA27|uniprotkb:A0A024RA61	psi-mi:txd16_human(display_long)|uniprotkb:TXNDC16(gene name)|psi-mi:TXNDC16(display_short)|uniprotkb:KIAA1344(gene name synonym)|uniprotkb:ERP90(gene name synonym)	psi-mi:roa2_human(display_long)|uniprotkb:HNRNPA2B1(gene name)|psi-mi:HNRNPA2B1(display_short)|uniprotkb:HNRPA2B1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771267|imex:IM-28143-86	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153519.1|refseq:NP_065835.2|ensembl:ENSG00000087301(gene)|ensembl:ENST00000281741(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR040090	go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|ensembl:ENST00000679001(transcript)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0050658"(RNA transport)|ensembl:ENST00000679021(transcript)|go:"GO:0070062"(extracellular exosome)|ensembl:ENST00000679123(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:1990428"(miRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034486|interpro:IPR034489|interpro:IPR035979|mint:P22626|rcsb pdb:1X4B|rcsb pdb:5EN1|rcsb pdb:5HO4|rcsb pdb:5WWE|rcsb pdb:5WWF|rcsb pdb:5WWG|rcsb pdb:6WPQ|rcsb pdb:6WQK|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|ensembl:ENSG00000122566(gene)|ensembl:ENST00000354667(transcript)|ensembl:ENST00000356674(transcript)|ensembl:ENST00000360787(transcript)|ensembl:ENST00000676746(transcript)|ensembl:ENST00000678675(transcript)|refseq:NP_002128.1|refseq:NP_112533.1|dip:DIP-32877N|refseq:XP_005249786.1|refseq:XP_016867598.1|refseq:XP_016867599.1|genbank_nucl_gi:133257(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:zzfV8NEefGI6L0ra5Z/bEg3WfEU9606	rogid:N2NeJVio9eYQULNcdE1KXtd2KPw9606	rigid:hhHVBRAkxdDgE5iPNo38wi8ZMFw	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9P2K2	uniprotkb:Q00839	intact:EBI-11126467|uniprotkb:Q9H9W7|uniprotkb:A7E260|uniprotkb:A7MD07|uniprotkb:B9EH67|uniprotkb:A5PKW9|ensembl:ENSP00000281741	intact:EBI-351126|uniprotkb:O75507|uniprotkb:Q8N174|uniprotkb:Q96HY9|uniprotkb:Q9BQ09|ensembl:ENSP00000491215	psi-mi:txd16_human(display_long)|uniprotkb:TXNDC16(gene name)|psi-mi:TXNDC16(display_short)|uniprotkb:KIAA1344(gene name synonym)|uniprotkb:ERP90(gene name synonym)	psi-mi:hnrpu_human(display_long)|uniprotkb:HNRNPU(gene name)|psi-mi:HNRNPU(display_short)|uniprotkb:SAFA(gene name synonym)|uniprotkb:U21.1(gene name synonym)|uniprotkb:HNRPU(gene name synonym)|uniprotkb:p120(gene name synonym)|uniprotkb:pp120(gene name synonym)|uniprotkb:C1orf199(gene name synonym)|uniprotkb:GRIP120(gene name synonym)|uniprotkb:Nuclear p120 ribonucleoprotein(gene name synonym)|uniprotkb:Scaffold-attachment factor A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771267|imex:IM-28143-86	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153519.1|refseq:NP_065835.2|ensembl:ENSG00000087301(gene)|ensembl:ENST00000281741(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR040090	refseq:NP_004492.2|refseq:NP_114032.2|ensembl:ENSG00000153187(gene)|ensembl:ENST00000640218(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:1990498"(mitotic spindle microtubule)|go:"GO:0098577"(inactive sex chromosome)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR026745|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q00839|rcsb pdb:1ZRJ|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902275"(regulation of chromatin organization)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902889"(protein localization to spindle microtubule)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990280"(RNA localization to chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005813"(centrosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0006396"(RNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008143"("poly(A) binding")|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0017069"(snRNA binding)|go:"GO:0017130"("poly(C) RNA binding")|go:"GO:0030496"(midbody)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034046"("poly(G) binding")|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051301"(cell division)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|refseq:XP_016856604.1|refseq:XP_016856605.1|refseq:XP_016856606.1|dip:DIP-684N|genbank_nucl_gi:126302554(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:zzfV8NEefGI6L0ra5Z/bEg3WfEU9606	rogid:n73PY0Vis+D5Iq0q77h5Ck2V4789606	rigid:hhHVBRAkxdDgE5iPNo38wi8ZMFw	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9P2K2	uniprotkb:P06733	intact:EBI-11126467|uniprotkb:Q9H9W7|uniprotkb:A7E260|uniprotkb:A7MD07|uniprotkb:B9EH67|uniprotkb:A5PKW9|ensembl:ENSP00000281741	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	psi-mi:txd16_human(display_long)|uniprotkb:TXNDC16(gene name)|psi-mi:TXNDC16(display_short)|uniprotkb:KIAA1344(gene name synonym)|uniprotkb:ERP90(gene name synonym)	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771267|imex:IM-28143-86	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153519.1|refseq:NP_065835.2|ensembl:ENSG00000087301(gene)|ensembl:ENST00000281741(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR040090	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667|genbank_nucl_gi:119339(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:zzfV8NEefGI6L0ra5Z/bEg3WfEU9606	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	rigid:hhHVBRAkxdDgE5iPNo38wi8ZMFw	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9P2K2	uniprotkb:P23284	intact:EBI-11126467|uniprotkb:Q9H9W7|uniprotkb:A7E260|uniprotkb:A7MD07|uniprotkb:B9EH67|uniprotkb:A5PKW9|ensembl:ENSP00000281741	intact:EBI-359252|uniprotkb:Q9BVK5|uniprotkb:A8K534|uniprotkb:Q6IBH5|ensembl:ENSP00000300026	psi-mi:txd16_human(display_long)|uniprotkb:TXNDC16(gene name)|psi-mi:TXNDC16(display_short)|uniprotkb:KIAA1344(gene name synonym)|uniprotkb:ERP90(gene name synonym)	psi-mi:ppib_human(display_long)|uniprotkb:PPIB(gene name)|psi-mi:PPIB(display_short)|uniprotkb:CYPB(gene name synonym)|uniprotkb:Cyclophilin B(gene name synonym)|uniprotkb:S-cyclophilin(gene name synonym)|uniprotkb:CYP-S1(gene name synonym)|uniprotkb:Rotamase B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771267|imex:IM-28143-86	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153519.1|refseq:NP_065835.2|ensembl:ENSG00000087301(gene)|ensembl:ENST00000281741(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR040090	refseq:NP_000933.1|ensembl:ENSG00000166794(gene)|ensembl:ENST00000300026(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016020"(membrane)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042470"(melanosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0060348"(bone development)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|mint:P23284|rcsb pdb:1CYN|rcsb pdb:3ICH|rcsb pdb:3ICI|reactome:R-HSA-1650814|genbank_nucl_gi:118090(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:zzfV8NEefGI6L0ra5Z/bEg3WfEU9606	rogid:h6nKaPUyEYUctYuu/3XfFhM4y9c9606	rigid:hhHVBRAkxdDgE5iPNo38wi8ZMFw	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9P2K2	uniprotkb:P42766	intact:EBI-11126467|uniprotkb:Q9H9W7|uniprotkb:A7E260|uniprotkb:A7MD07|uniprotkb:B9EH67|uniprotkb:A5PKW9|ensembl:ENSP00000281741	intact:EBI-356819|uniprotkb:Q4VBY5|uniprotkb:Q9BYF4|uniprotkb:Q5JTN5|uniprotkb:Q6IBC7|uniprotkb:Q96QJ7|uniprotkb:A8K4V7|ensembl:ENSP00000259469	psi-mi:txd16_human(display_long)|uniprotkb:TXNDC16(gene name)|psi-mi:TXNDC16(display_short)|uniprotkb:KIAA1344(gene name synonym)|uniprotkb:ERP90(gene name synonym)	psi-mi:rl35_human(display_long)|uniprotkb:RPL35(gene name)|psi-mi:RPL35(display_short)|uniprotkb:Large ribosomal subunit protein uL29(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771267|imex:IM-28143-86	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153519.1|refseq:NP_065835.2|ensembl:ENSG00000087301(gene)|ensembl:ENST00000281741(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR040090	refseq:NP_009140.1|ensembl:ENSG00000136942(gene)|ensembl:ENST00000348462(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR001854(Ribosomal protein L29)|interpro:IPR018254|interpro:IPR036049|mint:P42766|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|genbank_nucl_gi:1173039(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:zzfV8NEefGI6L0ra5Z/bEg3WfEU9606	rogid:jhzt7gCff2vdUb1Ff/VTBF698Pg9606	rigid:hhHVBRAkxdDgE5iPNo38wi8ZMFw	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9P2K2	uniprotkb:P21333	intact:EBI-11126467|uniprotkb:Q9H9W7|uniprotkb:A7E260|uniprotkb:A7MD07|uniprotkb:B9EH67|uniprotkb:A5PKW9|ensembl:ENSP00000281741	intact:EBI-350432|uniprotkb:Q8NF52|intact:EBI-1103234|ensembl:ENSP00000358866|uniprotkb:Q5HY53|uniprotkb:Q5HY55|uniprotkb:E9KL45	psi-mi:txd16_human(display_long)|uniprotkb:TXNDC16(gene name)|psi-mi:TXNDC16(display_short)|uniprotkb:KIAA1344(gene name synonym)|uniprotkb:ERP90(gene name synonym)	psi-mi:flna_human(display_long)|uniprotkb:FLNA(gene name)|psi-mi:FLNA(display_short)|uniprotkb:FLN(gene name synonym)|uniprotkb:FLN1(gene name synonym)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771267|imex:IM-28143-86	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153519.1|refseq:NP_065835.2|ensembl:ENSG00000087301(gene)|ensembl:ENST00000281741(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR040090	go:"GO:0007195"(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:"GO:1902396"(protein localization to bicellular tight junction)|refseq:NP_001104026.1|refseq:NP_001447.2|ensembl:ENSG00000196924(gene)|ensembl:ENST00000369850(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097368"(establishment of Sertoli cell barrier)|go:"GO:0097440"(apical dendrite)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:0046332"(SMAD binding)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0019900"(kinase binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031523"(Myb complex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045296"(cadherin binding)|reactome:R-HSA-114608|reactome:R-HSA-430116|reactome:R-HSA-446353|reactome:R-HSA-5627123|reactome:R-HSA-8983711|rcsb pdb:6EW1|go:"GO:1905031"(regulation of membrane repolarization during cardiac muscle cell action potential)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:P21333|rcsb pdb:2AAV|rcsb pdb:2BP3|rcsb pdb:2BRQ|rcsb pdb:2J3S|rcsb pdb:2JF1|rcsb pdb:2K3T|rcsb pdb:2K7P|rcsb pdb:2K7Q|rcsb pdb:2MTP|rcsb pdb:2W0P|rcsb pdb:2WFN|rcsb pdb:3CNK|rcsb pdb:3HOC|rcsb pdb:3HOP|rcsb pdb:3HOR|rcsb pdb:3ISW|rcsb pdb:3RGH|rcsb pdb:4M9P|rcsb pdb:4P3W|rcsb pdb:5XR1|rcsb pdb:6D8C|go:"GO:1905000"(regulation of membrane repolarization during atrial cardiac muscle cell action potential)|dip:DIP-1136N|genbank_nucl_gi:116241365(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:zzfV8NEefGI6L0ra5Z/bEg3WfEU9606	rogid:ZxGK5OSMy8cNsyt7Ax2KXb8bn9M9606	rigid:hhHVBRAkxdDgE5iPNo38wi8ZMFw	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BQE4	uniprotkb:Q9GZP9	intact:EBI-398970|uniprotkb:Q3B771|uniprotkb:Q9P0I6|ensembl:ENSP00000381282|ensembl:ENSP00000433541	intact:EBI-7962814|uniprotkb:Q9Y3A7|intact:MINT-3065126|ensembl:ENSP00000158771	psi-mi:sels_human(display_long)|uniprotkb:SELENOS(gene name)|psi-mi:SELENOS(display_short)|uniprotkb:SELS(gene name synonym)|uniprotkb:VCP-interacting membrane protein(gene name synonym)|uniprotkb:VIMP(gene name synonym)|uniprotkb:AD-015(orf name)|uniprotkb:SBBI8(orf name)	psi-mi:derl2_human(display_long)|uniprotkb:DERL2(gene name)|psi-mi:DERL2(display_short)|uniprotkb:DER2(gene name synonym)|uniprotkb:FLANA(gene name synonym)|uniprotkb:CGI-101(orf name)|uniprotkb:SBBI53(orf name)|uniprotkb:Der1-like protein 2(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 2(gene name synonym)|uniprotkb:F-LAN-1(gene name synonym)|uniprotkb:F-LANa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771216|imex:IM-28143-82	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060915.2|refseq:NP_982298.2|ensembl:ENSG00000131871(gene)|ensembl:ENST00000398226(transcript)|ensembl:ENST00000526049(transcript)|go:"GO:0002865"(negative regulation of acute inflammatory response to antigenic stimulus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006983"(ER overload response)|go:"GO:0009749"(response to glucose)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036502"(Derlin-1-VIMP complex)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051117"(ATPase binding)|go:"GO:0051775"(response to redox state)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080164"(regulation of nitric oxide metabolic process)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR009703(Selenoprotein S)|rcsb pdb:2Q2F|rcsb pdb:5KIU|rcsb pdb:5KIY|rcsb pdb:6DO4|reactome:R-HSA-8866654|go:"GO:0051771"(negative regulation of nitric-oxide synthase biosynthetic process)	refseq:NP_001291708.1|refseq:NP_057125.2|ensembl:ENSG00000072849(gene)|ensembl:ENST00000158771(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0001967"(suckling behavior)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|genbank_nucl_gi:50400648(identity)	-	-	comment:mint|function:"Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate. In contrast to DERL1, it is not involved in the degradation of MHC class I heavy chains following infection by cytomegaloviruses. May play a role in cell proliferation"	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:bg+Gf++/TqIgpUErI5PgcLomcCQ9606	rogid:hoayS/Xn9+pq/C61NYRu/1aOm6s9606	rigid:eqqne2gA6K7W5tERV3OZe3Mrl0o	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BQE4	uniprotkb:Q96CS3	intact:EBI-398970|uniprotkb:Q3B771|uniprotkb:Q9P0I6|ensembl:ENSP00000381282|ensembl:ENSP00000433541	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	psi-mi:sels_human(display_long)|uniprotkb:SELENOS(gene name)|psi-mi:SELENOS(display_short)|uniprotkb:SELS(gene name synonym)|uniprotkb:VCP-interacting membrane protein(gene name synonym)|uniprotkb:VIMP(gene name synonym)|uniprotkb:AD-015(orf name)|uniprotkb:SBBI8(orf name)	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771216|imex:IM-28143-82	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060915.2|refseq:NP_982298.2|ensembl:ENSG00000131871(gene)|ensembl:ENST00000398226(transcript)|ensembl:ENST00000526049(transcript)|go:"GO:0002865"(negative regulation of acute inflammatory response to antigenic stimulus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006983"(ER overload response)|go:"GO:0009749"(response to glucose)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036502"(Derlin-1-VIMP complex)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051117"(ATPase binding)|go:"GO:0051775"(response to redox state)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080164"(regulation of nitric oxide metabolic process)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR009703(Selenoprotein S)|rcsb pdb:2Q2F|rcsb pdb:5KIU|rcsb pdb:5KIY|rcsb pdb:6DO4|reactome:R-HSA-8866654|go:"GO:0051771"(negative regulation of nitric-oxide synthase biosynthetic process)	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N|genbank_nucl_gi:74731375(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:bg+Gf++/TqIgpUErI5PgcLomcCQ9606	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rigid:eqqne2gA6K7W5tERV3OZe3Mrl0o	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BQE4	uniprotkb:Q14139	intact:EBI-398970|uniprotkb:Q3B771|uniprotkb:Q9P0I6|ensembl:ENSP00000381282|ensembl:ENSP00000433541	intact:EBI-1048119|uniprotkb:Q2M1H0|uniprotkb:Q6P5T4|uniprotkb:Q7Z639|uniprotkb:B0YJB6|ensembl:ENSP00000252108	psi-mi:sels_human(display_long)|uniprotkb:SELENOS(gene name)|psi-mi:SELENOS(display_short)|uniprotkb:SELS(gene name synonym)|uniprotkb:VCP-interacting membrane protein(gene name synonym)|uniprotkb:VIMP(gene name synonym)|uniprotkb:AD-015(orf name)|uniprotkb:SBBI8(orf name)	psi-mi:ube4a_human(display_long)|uniprotkb:UBE4A(gene name)|psi-mi:UBE4A(display_short)|uniprotkb:KIAA0126(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase E4 A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771216|imex:IM-28143-82	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060915.2|refseq:NP_982298.2|ensembl:ENSG00000131871(gene)|ensembl:ENST00000398226(transcript)|ensembl:ENST00000526049(transcript)|go:"GO:0002865"(negative regulation of acute inflammatory response to antigenic stimulus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006983"(ER overload response)|go:"GO:0009749"(response to glucose)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036502"(Derlin-1-VIMP complex)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051117"(ATPase binding)|go:"GO:0051775"(response to redox state)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080164"(regulation of nitric oxide metabolic process)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR009703(Selenoprotein S)|rcsb pdb:2Q2F|rcsb pdb:5KIU|rcsb pdb:5KIY|rcsb pdb:6DO4|reactome:R-HSA-8866654|go:"GO:0051771"(negative regulation of nitric-oxide synthase biosynthetic process)	refseq:NP_001191006.1|refseq:NP_004779.2|ensembl:ENSG00000110344(gene)|ensembl:ENST00000252108(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019474|rcsb pdb:1WGM|reactome:R-HSA-983168|genbank_nucl_gi:71164791(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:bg+Gf++/TqIgpUErI5PgcLomcCQ9606	rogid:nk+uYWQ8ytS/qOjUkCDf9dAymPU9606	rigid:eqqne2gA6K7W5tERV3OZe3Mrl0o	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BQE4	uniprotkb:P55072	intact:EBI-398970|uniprotkb:Q3B771|uniprotkb:Q9P0I6|ensembl:ENSP00000381282|ensembl:ENSP00000433541	intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777	psi-mi:sels_human(display_long)|uniprotkb:SELENOS(gene name)|psi-mi:SELENOS(display_short)|uniprotkb:SELS(gene name synonym)|uniprotkb:VCP-interacting membrane protein(gene name synonym)|uniprotkb:VIMP(gene name synonym)|uniprotkb:AD-015(orf name)|uniprotkb:SBBI8(orf name)	psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771216|imex:IM-28143-82	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060915.2|refseq:NP_982298.2|ensembl:ENSG00000131871(gene)|ensembl:ENST00000398226(transcript)|ensembl:ENST00000526049(transcript)|go:"GO:0002865"(negative regulation of acute inflammatory response to antigenic stimulus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006983"(ER overload response)|go:"GO:0009749"(response to glucose)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036502"(Derlin-1-VIMP complex)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051117"(ATPase binding)|go:"GO:0051775"(response to redox state)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080164"(regulation of nitric oxide metabolic process)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR009703(Selenoprotein S)|rcsb pdb:2Q2F|rcsb pdb:5KIU|rcsb pdb:5KIY|rcsb pdb:6DO4|reactome:R-HSA-8866654|go:"GO:0051771"(negative regulation of nitric-oxide synthase biosynthetic process)	refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N|genbank_nucl_gi:6094447(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:bg+Gf++/TqIgpUErI5PgcLomcCQ9606	rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606	rigid:eqqne2gA6K7W5tERV3OZe3Mrl0o	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BQE4	uniprotkb:Q9BUN8	intact:EBI-398970|uniprotkb:Q3B771|uniprotkb:Q9P0I6|ensembl:ENSP00000381282|ensembl:ENSP00000433541	intact:EBI-398977|uniprotkb:B3KW41|uniprotkb:E9PH19|ensembl:ENSP00000259512	psi-mi:sels_human(display_long)|uniprotkb:SELENOS(gene name)|psi-mi:SELENOS(display_short)|uniprotkb:SELS(gene name synonym)|uniprotkb:VCP-interacting membrane protein(gene name synonym)|uniprotkb:VIMP(gene name synonym)|uniprotkb:AD-015(orf name)|uniprotkb:SBBI8(orf name)	psi-mi:derl1_human(display_long)|uniprotkb:DERL1(gene name)|psi-mi:DERL1(display_short)|uniprotkb:UNQ243/PRO276(orf name)|uniprotkb:Der1-like protein 1(gene name synonym)|uniprotkb:Degradation in endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:DER1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771216|imex:IM-28143-82	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060915.2|refseq:NP_982298.2|ensembl:ENSG00000131871(gene)|ensembl:ENST00000398226(transcript)|ensembl:ENST00000526049(transcript)|go:"GO:0002865"(negative regulation of acute inflammatory response to antigenic stimulus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006983"(ER overload response)|go:"GO:0009749"(response to glucose)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036502"(Derlin-1-VIMP complex)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051117"(ATPase binding)|go:"GO:0051775"(response to redox state)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080164"(regulation of nitric oxide metabolic process)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR009703(Selenoprotein S)|rcsb pdb:2Q2F|rcsb pdb:5KIU|rcsb pdb:5KIY|rcsb pdb:6DO4|reactome:R-HSA-8866654|go:"GO:0051771"(negative regulation of nitric-oxide synthase biosynthetic process)	refseq:NP_001128143.1|refseq:NP_077271.1|ensembl:ENSG00000136986(gene)|ensembl:ENST00000259512(transcript)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0002020"(protease binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0036502"(Derlin-1-VIMP complex)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007599(Der1-like)|interpro:IPR035952|rcsb pdb:5GLF|rcsb pdb:7CZB|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5678895|reactome:R-HSA-8866654|genbank_nucl_gi:50400630(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:bg+Gf++/TqIgpUErI5PgcLomcCQ9606	rogid:M35Ah+CuYuV7RP1edsda6vU7Bgo9606	rigid:eqqne2gA6K7W5tERV3OZe3Mrl0o	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BQE4	uniprotkb:O00124	intact:EBI-398970|uniprotkb:Q3B771|uniprotkb:Q9P0I6|ensembl:ENSP00000381282|ensembl:ENSP00000433541	intact:EBI-1993850|uniprotkb:Q7Z6F2	psi-mi:sels_human(display_long)|uniprotkb:SELENOS(gene name)|psi-mi:SELENOS(display_short)|uniprotkb:SELS(gene name synonym)|uniprotkb:VCP-interacting membrane protein(gene name synonym)|uniprotkb:VIMP(gene name synonym)|uniprotkb:AD-015(orf name)|uniprotkb:SBBI8(orf name)	psi-mi:ubxn8_human(display_long)|uniprotkb:UBXN8(gene name)|psi-mi:UBXN8(display_short)|uniprotkb:D8S2298E(gene name synonym)|uniprotkb:REP8(gene name synonym)|uniprotkb:UBXD6(gene name synonym)|uniprotkb:UBX domain-containing protein 6(gene name synonym)|uniprotkb:Reproduction 8 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771216|imex:IM-28143-82	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060915.2|refseq:NP_982298.2|ensembl:ENSG00000131871(gene)|ensembl:ENST00000398226(transcript)|ensembl:ENST00000526049(transcript)|go:"GO:0002865"(negative regulation of acute inflammatory response to antigenic stimulus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006983"(ER overload response)|go:"GO:0009749"(response to glucose)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036502"(Derlin-1-VIMP complex)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051117"(ATPase binding)|go:"GO:0051775"(response to redox state)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080164"(regulation of nitric oxide metabolic process)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR009703(Selenoprotein S)|rcsb pdb:2Q2F|rcsb pdb:5KIU|rcsb pdb:5KIY|rcsb pdb:6DO4|reactome:R-HSA-8866654|go:"GO:0051771"(negative regulation of nitric-oxide synthase biosynthetic process)	refseq:NP_005662.1|interpro:IPR001012(UBX)|interpro:IPR017247(UBX , Rep6)|interpro:IPR029071|refseq:NP_001269118.1|refseq:NP_001269128.1|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007338"(single fertilization)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|genbank_nucl_gi:3915830(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:bg+Gf++/TqIgpUErI5PgcLomcCQ9606	rogid:trPGnzbb5gS67+tqyKRObciKV8M9606	rigid:eqqne2gA6K7W5tERV3OZe3Mrl0o	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BQE4	uniprotkb:Q9Y2U9	intact:EBI-398970|uniprotkb:Q3B771|uniprotkb:Q9P0I6|ensembl:ENSP00000381282|ensembl:ENSP00000433541	intact:EBI-715326|uniprotkb:Q86TY9|uniprotkb:Q6IAF0|uniprotkb:B3KPF9|ensembl:ENSP00000298307	psi-mi:sels_human(display_long)|uniprotkb:SELENOS(gene name)|psi-mi:SELENOS(display_short)|uniprotkb:SELS(gene name synonym)|uniprotkb:VCP-interacting membrane protein(gene name synonym)|uniprotkb:VIMP(gene name synonym)|uniprotkb:AD-015(orf name)|uniprotkb:SBBI8(orf name)	psi-mi:kldc2_human(display_long)|uniprotkb:Hepatocellular carcinoma-associated antigen 33(gene name synonym)|uniprotkb:Host cell factor homolog LCP(gene name synonym)|uniprotkb:Host cell factor-like protein 1(gene name synonym)|uniprotkb:KLHDC2(gene name)|psi-mi:KLHDC2(display_short)|uniprotkb:HCA33(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771216|imex:IM-28143-82	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060915.2|refseq:NP_982298.2|ensembl:ENSG00000131871(gene)|ensembl:ENST00000398226(transcript)|ensembl:ENST00000526049(transcript)|go:"GO:0002865"(negative regulation of acute inflammatory response to antigenic stimulus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006983"(ER overload response)|go:"GO:0009749"(response to glucose)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036502"(Derlin-1-VIMP complex)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051117"(ATPase binding)|go:"GO:0051775"(response to redox state)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080164"(regulation of nitric oxide metabolic process)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR009703(Selenoprotein S)|rcsb pdb:2Q2F|rcsb pdb:5KIU|rcsb pdb:5KIY|rcsb pdb:6DO4|reactome:R-HSA-8866654|go:"GO:0051771"(negative regulation of nitric-oxide synthase biosynthetic process)	refseq:NP_055130.1|ensembl:ENSG00000165516(gene)|ensembl:ENST00000298307(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0140627"(ubiquitin-dependent protein catabolic process via the C-end degron rule pathway)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR015915(Kelch-type beta propeller)|mint:Q9Y2U9|rcsb pdb:6DO3|rcsb pdb:6DO4|rcsb pdb:6DO5|go:"GO:0016604"(nuclear body)|genbank_nucl_gi:28380093(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:bg+Gf++/TqIgpUErI5PgcLomcCQ9606	rogid:YWJMGSX2MqvROFP492LhtVCjgrw9606	rigid:eqqne2gA6K7W5tERV3OZe3Mrl0o	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9BQE4	uniprotkb:Q9Y6D0	intact:EBI-398970|uniprotkb:Q3B771|uniprotkb:Q9P0I6|ensembl:ENSP00000381282|ensembl:ENSP00000433541	intact:EBI-9679163|uniprotkb:Q8IZQ3|uniprotkb:Q9P085|ensembl:ENSP00000418813	psi-mi:sels_human(display_long)|uniprotkb:SELENOS(gene name)|psi-mi:SELENOS(display_short)|uniprotkb:SELS(gene name synonym)|uniprotkb:VCP-interacting membrane protein(gene name synonym)|uniprotkb:VIMP(gene name synonym)|uniprotkb:AD-015(orf name)|uniprotkb:SBBI8(orf name)	psi-mi:selk_human(display_long)|uniprotkb:SELENOK(gene name)|psi-mi:SELENOK(display_short)|uniprotkb:SELK(gene name synonym)|uniprotkb:HSPC030(orf name)|uniprotkb:HSPC297(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771216|imex:IM-28143-82	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060915.2|refseq:NP_982298.2|ensembl:ENSG00000131871(gene)|ensembl:ENST00000398226(transcript)|ensembl:ENST00000526049(transcript)|go:"GO:0002865"(negative regulation of acute inflammatory response to antigenic stimulus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006983"(ER overload response)|go:"GO:0009749"(response to glucose)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036502"(Derlin-1-VIMP complex)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051117"(ATPase binding)|go:"GO:0051775"(response to redox state)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080164"(regulation of nitric oxide metabolic process)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000110"(negative regulation of macrophage apoptotic process)|interpro:IPR009703(Selenoprotein S)|rcsb pdb:2Q2F|rcsb pdb:5KIU|rcsb pdb:5KIY|rcsb pdb:6DO4|reactome:R-HSA-8866654|go:"GO:0051771"(negative regulation of nitric-oxide synthase biosynthetic process)	refseq:NP_067060.2|ensembl:ENSG00000113811(gene)|ensembl:ENST00000495461(transcript)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045728"(respiratory burst after phagocytosis)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:2000406"(positive regulation of T cell migration)|interpro:IPR024491|rcsb pdb:6DO3|genbank_nucl_gi:25014099(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:bg+Gf++/TqIgpUErI5PgcLomcCQ9606	rogid:e0SoDHprfiTOiInNeRHt0mWfPWU9606	rigid:eqqne2gA6K7W5tERV3OZe3Mrl0o	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NPA0	uniprotkb:Q8N4V1	intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5	intact:EBI-6163737|ensembl:ENSP00000306220|ensembl:ENSP00000505226|uniprotkb:B2R625|uniprotkb:B4DIY3|uniprotkb:D3DWG7|uniprotkb:Q5JPP7	psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name)	psi-mi:emc5_human(display_long)|uniprotkb:MMGT1(gene name)|psi-mi:MMGT1(display_short)|uniprotkb:TMEM32(gene name synonym)|uniprotkb:Transmembrane protein 32(gene name synonym)|uniprotkb:EMC5(gene name synonym)|uniprotkb:Membrane magnesium transporter 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771078|imex:IM-28143-80	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1	go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-5223345|ensembl:ENSG00000169446(gene)|ensembl:ENST00000305963(transcript)|ensembl:ENST00000679621(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|refseq:NP_775741.1|refseq:NP_001316929.1|genbank_nucl_gi:74751006(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606	rogid:Kq+VEYt+fwoOsEfcgZ1K1vkFFN49606	rigid:RWxg9biJhNt5U6eq9LVTKPSEq/w	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NPA0	uniprotkb:Q8N766	intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5	intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62	psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name)	psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771078|imex:IM-28143-80	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1	go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1|genbank_nucl_gi:74751081(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606	rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606	rigid:RWxg9biJhNt5U6eq9LVTKPSEq/w	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NPA0	uniprotkb:Q9BV81	intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5	intact:EBI-2820492|ensembl:ENSP00000248378|ensembl:ENSP00000380322	psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name)	psi-mi:emc6_human(display_long)|uniprotkb:EMC6(gene name)|psi-mi:EMC6(display_short)|uniprotkb:TMEM93(gene name synonym)|uniprotkb:Transmembrane protein 93(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771078|imex:IM-28143-80	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1	refseq:NP_001014764.1|refseq:NP_112588.1|ensembl:ENSG00000127774(gene)|ensembl:ENST00000248378(transcript)|ensembl:ENST00000397133(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0097631"(integral component of omegasome membrane)|interpro:IPR008504(Protein of unknown function DUF786)|interpro:IPR029008|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|go:"GO:0072546"(EMC complex)|genbank_nucl_gi:74733294(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606	rogid:GPnTCJqAA2eIiiP17pgtIhGnpsA9606	rigid:RWxg9biJhNt5U6eq9LVTKPSEq/w	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NPA0	uniprotkb:Q96KA5	intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5	intact:EBI-3216282|ensembl:ENSP00000313854|ensembl:ENSP00000480372|uniprotkb:Q96AZ0|uniprotkb:Q7LG29|uniprotkb:Q9H3N4|uniprotkb:Q658W6|uniprotkb:D3DTC1	psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name)	psi-mi:clp1l_human(display_long)|uniprotkb:CLPTM1L(gene name)|psi-mi:CLPTM1L(display_short)|uniprotkb:CRR9(gene name synonym)|uniprotkb:Cisplatin resistance-related protein 9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771078|imex:IM-28143-80	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1	ensembl:ENSG00000049656(gene)|ensembl:ENSG00000274811(gene)|ensembl:ENST00000320895(transcript)|ensembl:ENST00000620010(transcript)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR008429(Cleft lip and palate transmembrane 1)|interpro:IPR030434|mint:Q96KA5|refseq:NP_110409.2|genbank_nucl_gi:74732209(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606	rogid:G5sRyV1/Kt1rgQ4usxNWoa4MFFU9606	rigid:RWxg9biJhNt5U6eq9LVTKPSEq/w	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NPA0	uniprotkb:Q5UCC4	intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5	intact:EBI-11284388|uniprotkb:Q5UCC6|uniprotkb:Q69YT5|uniprotkb:Q6UWP3|uniprotkb:Q86YL4|uniprotkb:Q8N541|ensembl:ENSP00000334037	psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name)	psi-mi:emc10_human(display_long)|uniprotkb:EMC10(gene name)|psi-mi:EMC10(display_short)|uniprotkb:C19orf63(gene name synonym)|uniprotkb:Hematopoietic signal peptide-containing membrane domain-containing protein 1(gene name synonym)|uniprotkb:INM02(gene name synonym)|uniprotkb:UNQ764/PRO1556(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771078|imex:IM-28143-80	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1	refseq:NP_778233.4|refseq:NP_996261.1|ensembl:ENSG00000161671(gene)|ensembl:ENST00000334976(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005576"(extracellular region)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR029615|mint:Q5UCC4|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|genbank_nucl_gi:74708213(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606	rogid:NEJjkw5uEJnzNUW7MkZIm/ELpA89606	rigid:RWxg9biJhNt5U6eq9LVTKPSEq/w	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NPA0	uniprotkb:Q9P0I2	intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5	intact:EBI-1054670|uniprotkb:Q53GH8|uniprotkb:Q6ZMC2|uniprotkb:B2R4Z9|ensembl:ENSP00000245046	psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name)	psi-mi:emc3_human(display_long)|uniprotkb:EMC3(gene name)|psi-mi:EMC3(display_short)|uniprotkb:TMEM111(gene name synonym)|uniprotkb:Transmembrane protein 111(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771078|imex:IM-28143-80	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1	refseq:NP_060917.1|ensembl:ENSG00000125037(gene)|ensembl:ENST00000245046(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008568(Protein of unknown function DUF850, transmembrane eukaryotic)|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-8980692|genbank_nucl_gi:71153383(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606	rogid:VbIl0nFhcDMIPTxmBclaIMtbVU09606	rigid:RWxg9biJhNt5U6eq9LVTKPSEq/w	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NPA0	uniprotkb:Q15006	intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5	intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853	psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name)	psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771078|imex:IM-28143-80	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1	refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|genbank_nucl_gi:3183217(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606	rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606	rigid:RWxg9biJhNt5U6eq9LVTKPSEq/w	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NPA0	uniprotkb:O43402	intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5	intact:EBI-741841|ensembl:ENSP00000253457|uniprotkb:C9JB21	psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name)	psi-mi:emc8_human(display_long)|uniprotkb:EMC8(gene name)|psi-mi:EMC8(display_short)|uniprotkb:C16orf2(gene name synonym)|uniprotkb:C16orf4(gene name synonym)|uniprotkb:COX4AL(gene name synonym)|uniprotkb:COX4NB(gene name synonym)|uniprotkb:FAM158B(gene name synonym)|uniprotkb:NOC4(gene name synonym)|uniprotkb:Neighbor of COX4(gene name synonym)|uniprotkb:Protein FAM158B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771078|imex:IM-28143-80	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1	refseq:NP_006058.1|ensembl:ENSG00000131148(gene)|ensembl:ENST00000253457(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6WW7|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_001135760.1|genbank_nucl_gi:18202040(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606	rogid:cGQFR1ZU2L/KgikqLELVUzplhTU9606	rigid:RWxg9biJhNt5U6eq9LVTKPSEq/w	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NPA0	uniprotkb:Q9UHD9	intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5	intact:EBI-947187|uniprotkb:O94798|uniprotkb:Q9H3W6|uniprotkb:Q9HAZ4|uniprotkb:Q5D027|intact:EBI-28967571|ensembl:ENSP00000345195	psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name)	psi-mi:ubql2_human(display_long)|uniprotkb:UBQLN2(gene name)|psi-mi:UBQLN2(display_short)|uniprotkb:PLIC2(gene name synonym)|uniprotkb:HRIHFB2157(orf name)|uniprotkb:N4BP4(gene name synonym)|uniprotkb:Protein linking IAP with cytoskeleton 2(gene name synonym)|uniprotkb:Ubiquitin-like product Chap1/Dsk2(gene name synonym)|uniprotkb:DSK2 homolog(gene name synonym)|uniprotkb:Chap1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771078|imex:IM-28143-80	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1	ensembl:ENSP00000345195|refseq:NP_038472.2|dip:DIP-42116N|ensembl:ENSG00000188021(gene)|ensembl:ENST00000338222(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:1900186"(negative regulation of clathrin-dependent endocytosis)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1904021"(negative regulation of G protein-coupled receptor internalization)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR000626(Ubiquitin)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028430|interpro:IPR029071|mint:Q9UHD9|rcsb pdb:1J8C|rcsb pdb:2NBV|rcsb pdb:6MUN|reactome:R-HSA-8856825|genbank_nucl_gi:124056593(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606	rogid:tElcz7gHFkKFVDTz3PXeNcaBP7U9606	rigid:RWxg9biJhNt5U6eq9LVTKPSEq/w	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9NPA0	uniprotkb:Q9Y3B6	intact:EBI-6309137|ensembl:ENSP00000256545|uniprotkb:B2RC00|uniprotkb:Q96ED5	intact:EBI-748366|uniprotkb:Q9BUM3|uniprotkb:D3DS60|ensembl:ENSP00000216799|ensembl:ENSP00000403210|ensembl:ENSP00000494976|ensembl:ENSP00000495623	psi-mi:emc7_human(display_long)|uniprotkb:EMC7(gene name)|psi-mi:EMC7(display_short)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:C15orf24(gene name synonym)|uniprotkb:HT022(orf name)|uniprotkb:UNQ905/PRO1926(orf name)	psi-mi:emc9_human(display_long)|uniprotkb:EMC9(gene name)|psi-mi:EMC9(display_short)|uniprotkb:C14orf122(gene name synonym)|uniprotkb:FAM158A(gene name synonym)|uniprotkb:Protein FAM158A(gene name synonym)|uniprotkb:CGI-112(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771078|imex:IM-28143-80	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000134153(gene)|ensembl:ENST00000256545(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR019008|interpro:IPR039163|rcsb pdb:1B0G|rcsb pdb:1LP9|rcsb pdb:2J8U|rcsb pdb:2JCC|rcsb pdb:2UWE|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|refseq:NP_064539.1	refseq:NP_057133.2|refseq:XP_005267778.1|ensembl:ENSG00000100908(gene)|ensembl:ENSG00000285377(gene)|ensembl:ENST00000216799(transcript)|ensembl:ENST00000419198(transcript)|ensembl:ENST00000642147(transcript)|ensembl:ENST00000646772(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6Y4L|rcsb pdb:6Z3W|genbank_nucl_gi:116241305(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:XBg97fKNpvbssNf6YFewsWDmiBE9606	rogid:ZMbNxmOKb2r2KzWdB5JF/kGPSaU9606	rigid:RWxg9biJhNt5U6eq9LVTKPSEq/w	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q13438	uniprotkb:Q86WA8	intact:EBI-725454|intact:EBI-1174342|uniprotkb:A6NDD1|uniprotkb:A6NFR7|uniprotkb:A6NLB2|uniprotkb:A8K5Q9|uniprotkb:B4DPX1|uniprotkb:B4E1I6|uniprotkb:E7ENT8|uniprotkb:F8VUH2|uniprotkb:O00579|uniprotkb:Q6IBL2|uniprotkb:Q8IZ58|uniprotkb:Q9BW99|uniprotkb:B4DE28|ensembl:ENSP00000318165|uniprotkb:E7EW91|uniprotkb:G3XA88	intact:EBI-2513996|ensembl:ENSP00000285737|uniprotkb:Q96K43|uniprotkb:Q8N3B9|uniprotkb:Q0D2H6|uniprotkb:Q8NCE9|uniprotkb:B7ZKL7	psi-mi:os9_human(display_long)|uniprotkb:OS9(gene name)|psi-mi:OS9(display_short)|uniprotkb:Amplified in osteosarcoma 9(gene name synonym)	psi-mi:lonp2_human(display_long)|uniprotkb:LONP2(gene name)|psi-mi:LONP2(display_short)|uniprotkb:LONP(gene name synonym)|uniprotkb:Lon protease-like protein 2(gene name synonym)|uniprotkb:Peroxisomal Lon protease(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771060|imex:IM-28143-104	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006803.1|refseq:NP_001017956.1|refseq:NP_001017957.1|refseq:NP_001017958.1|refseq:NP_001248349.1|refseq:NP_001248350.1|refseq:NP_001248351.1|refseq:NP_001248352.1|ensembl:ENSG00000135506(gene)|ensembl:ENST00000315970(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0002020"(protease binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006605"(protein targeting)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|interpro:IPR044865|rcsb pdb:3AIH|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-37493N	ensembl:ENSG00000102910(gene)|ensembl:ENST00000285737(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006625"(protein targeting to peroxisome)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008233"(peptidase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0019899"(enzyme binding)|go:"GO:0031998"(regulation of fatty acid beta-oxidation)|interpro:IPR003111(Peptidase S16, lon N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR004815(Peptidase S16, ATP-dependent protease La)|interpro:IPR008268(Peptidase S16, active site)|interpro:IPR008269(Peptidase S16, lon C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR015947(PUA-like)|interpro:IPR020568|interpro:IPR027065|interpro:IPR027417|interpro:IPR027501|reactome:R-HSA-390471|reactome:R-HSA-9033241|refseq:NP_001287877.1|refseq:NP_113678.2|genbank_nucl_gi:74727668(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:Ntc3geE7th+rBeIp0MxuUuu/28Y9606	rogid:WyZglDz2aZOpnRVtWTrAf62G0pA9606	rigid:IetFC9WaB0PvB9sHbhx0xqrvimQ	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q13438	uniprotkb:Q9UBV2	intact:EBI-725454|intact:EBI-1174342|uniprotkb:A6NDD1|uniprotkb:A6NFR7|uniprotkb:A6NLB2|uniprotkb:A8K5Q9|uniprotkb:B4DPX1|uniprotkb:B4E1I6|uniprotkb:E7ENT8|uniprotkb:F8VUH2|uniprotkb:O00579|uniprotkb:Q6IBL2|uniprotkb:Q8IZ58|uniprotkb:Q9BW99|uniprotkb:B4DE28|ensembl:ENSP00000318165|uniprotkb:E7EW91|uniprotkb:G3XA88	intact:EBI-358766|uniprotkb:Q6UWT6|uniprotkb:Q9P1T9|uniprotkb:Q9UHK7|ensembl:ENSP00000337053	psi-mi:os9_human(display_long)|uniprotkb:OS9(gene name)|psi-mi:OS9(display_short)|uniprotkb:Amplified in osteosarcoma 9(gene name synonym)	psi-mi:se1l1_human(display_long)|uniprotkb:SEL1L(gene name)|psi-mi:SEL1L(display_short)|uniprotkb:TSA305(gene name synonym)|uniprotkb:UNQ128/PRO1063(orf name)|uniprotkb:Suppressor of lin-12-like protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771060|imex:IM-28143-104	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006803.1|refseq:NP_001017956.1|refseq:NP_001017957.1|refseq:NP_001017958.1|refseq:NP_001248349.1|refseq:NP_001248350.1|refseq:NP_001248351.1|refseq:NP_001248352.1|ensembl:ENSG00000135506(gene)|ensembl:ENST00000315970(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0002020"(protease binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006605"(protein targeting)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|interpro:IPR044865|rcsb pdb:3AIH|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-37493N	refseq:NP_001231913.1|refseq:NP_005056.3|ensembl:ENSG00000071537(gene)|ensembl:ENST00000336735(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0050821"(protein stabilization)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|mint:Q9UBV2|reactome:R-HSA-1912420|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-46259N|genbank_nucl_gi:62512184(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:Ntc3geE7th+rBeIp0MxuUuu/28Y9606	rogid:eufE+8nfcHK8CDl+AQ5G+3NtL+09606	rigid:IetFC9WaB0PvB9sHbhx0xqrvimQ	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q13438	uniprotkb:P35579	intact:EBI-725454|intact:EBI-1174342|uniprotkb:A6NDD1|uniprotkb:A6NFR7|uniprotkb:A6NLB2|uniprotkb:A8K5Q9|uniprotkb:B4DPX1|uniprotkb:B4E1I6|uniprotkb:E7ENT8|uniprotkb:F8VUH2|uniprotkb:O00579|uniprotkb:Q6IBL2|uniprotkb:Q8IZ58|uniprotkb:Q9BW99|uniprotkb:B4DE28|ensembl:ENSP00000318165|uniprotkb:E7EW91|uniprotkb:G3XA88	intact:EBI-350338|uniprotkb:O60805|ensembl:ENSP00000216181|uniprotkb:Q86T83|intact:EBI-1054343|uniprotkb:A8K6E4|uniprotkb:Q60FE2	psi-mi:os9_human(display_long)|uniprotkb:OS9(gene name)|psi-mi:OS9(display_short)|uniprotkb:Amplified in osteosarcoma 9(gene name synonym)	psi-mi:myh9_human(display_long)|uniprotkb:MYH9(gene name)|psi-mi:MYH9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771060|imex:IM-28143-104	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006803.1|refseq:NP_001017956.1|refseq:NP_001017957.1|refseq:NP_001017958.1|refseq:NP_001248349.1|refseq:NP_001248350.1|refseq:NP_001248351.1|refseq:NP_001248352.1|ensembl:ENSG00000135506(gene)|ensembl:ENST00000315970(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0002020"(protease binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006605"(protein targeting)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|interpro:IPR044865|rcsb pdb:3AIH|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-37493N	refseq:NP_002464.1|ensembl:ENSG00000100345(gene)|ensembl:ENST00000216181(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001931"(uropod)|go:"GO:0003723"(RNA binding)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|refseq:XP_011528499.1|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030220"(platelet formation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032418"(lysosome localization)|go:"GO:0032506"(cytokinetic process)|go:"GO:0032796"(uropod organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045296"(cadherin binding)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051015"(actin filament binding)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0097513"(myosin II filament)|go:"GO:1903919"(negative regulation of actin filament severing)|rcsb pdb:4CFR|rcsb pdb:4ETO|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9662834|reactome:R-HSA-9664422|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1905684"(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036305|interpro:IPR036961|mint:P35579|rcsb pdb:2LNK|rcsb pdb:3ZWH|rcsb pdb:4CFQ|refseq:XP_016884292.1|refseq:XP_016884293.1|refseq:XP_016884294.1|refseq:XP_016884295.1|dip:DIP-33103N|genbank_nucl_gi:6166599(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:Ntc3geE7th+rBeIp0MxuUuu/28Y9606	rogid:fSOtpFpr8PSnAG5UdAr/khwkzJs9606	rigid:IetFC9WaB0PvB9sHbhx0xqrvimQ	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q13438	uniprotkb:P14625	intact:EBI-725454|intact:EBI-1174342|uniprotkb:A6NDD1|uniprotkb:A6NFR7|uniprotkb:A6NLB2|uniprotkb:A8K5Q9|uniprotkb:B4DPX1|uniprotkb:B4E1I6|uniprotkb:E7ENT8|uniprotkb:F8VUH2|uniprotkb:O00579|uniprotkb:Q6IBL2|uniprotkb:Q8IZ58|uniprotkb:Q9BW99|uniprotkb:B4DE28|ensembl:ENSP00000318165|uniprotkb:E7EW91|uniprotkb:G3XA88	intact:EBI-359129|uniprotkb:Q96A97|ensembl:ENSP00000299767	psi-mi:os9_human(display_long)|uniprotkb:OS9(gene name)|psi-mi:OS9(display_short)|uniprotkb:Amplified in osteosarcoma 9(gene name synonym)	psi-mi:enpl_human(display_long)|uniprotkb:HSP90B1(gene name)|psi-mi:HSP90B1(display_short)|uniprotkb:TRA1(gene name synonym)|uniprotkb:Heat shock protein 90 kDa beta member 1(gene name synonym)|uniprotkb:94 kDa glucose-regulated protein(gene name synonym)|uniprotkb:GRP94(gene name synonym)|uniprotkb:gp96 homolog(gene name synonym)|uniprotkb:Tumor rejection antigen 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771060|imex:IM-28143-104	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006803.1|refseq:NP_001017956.1|refseq:NP_001017957.1|refseq:NP_001017958.1|refseq:NP_001248349.1|refseq:NP_001248350.1|refseq:NP_001248351.1|refseq:NP_001248352.1|ensembl:ENSG00000135506(gene)|ensembl:ENST00000315970(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0002020"(protease binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006605"(protein targeting)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR012913(Glucosidase II beta subunit-like)|interpro:IPR044865|rcsb pdb:3AIH|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-37493N	refseq:NP_003290.1|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051208"(sequestering of calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071682"(endocytic vesicle lumen)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P14625|rcsb pdb:4NH9|reactome:R-HSA-1679131|reactome:R-HSA-3000480|reactome:R-HSA-381183|reactome:R-HSA-381426|reactome:R-HSA-6785807|reactome:R-HSA-8957275|ensembl:ENSG00000166598(gene)|ensembl:ENST00000299767(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031247"(actin rod assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|dip:DIP-36060N|genbank_nucl_gi:119360(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:Ntc3geE7th+rBeIp0MxuUuu/28Y9606	rogid:m5CdlplqVyMUWYe75aKDuMzztMY9606	rigid:IetFC9WaB0PvB9sHbhx0xqrvimQ	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWF2	uniprotkb:O75445	intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401	intact:EBI-9996372|uniprotkb:Q5VVM9|uniprotkb:Q6S362|uniprotkb:Q9NS27|ensembl:ENSP00000305941	psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym)	psi-mi:ush2a_human(display_long)|uniprotkb:USH2A(gene name)|psi-mi:USH2A(display_short)|uniprotkb:Usher syndrome type IIa protein(gene name synonym)|uniprotkb:Usher syndrome type-2A protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771114|imex:IM-28143-62	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N	refseq:NP_009054.5|refseq:NP_996816.2|ensembl:ENSG00000042781(gene)|ensembl:ENST00000307340(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002141"(stereocilia ankle link)|go:"GO:0002142"(stereocilia ankle link complex)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0017022"(myosin binding)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0050896"(response to stimulus)|go:"GO:0050953"(sensory perception of light stimulus)|go:"GO:0060113"(inner ear receptor cell differentiation)|go:"GO:0060171"(stereocilium membrane)|go:"GO:1990696"(USH2 complex)|interpro:IPR001791(Laminin G)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006558(LamG-like jellyroll fold)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR026915|interpro:IPR036116|go:"GO:1990075"(periciliary membrane compartment)|genbank_nucl_gi:91207975(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606	rogid:VnMdoTos3yfkcuy8wI6XTJrq+Go9606	rigid:C4TpH/vx6vdJ4LhXeaQzMwUuuys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWF2	uniprotkb:Q14697	intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401	intact:EBI-348004|ensembl:ENSP00000349053|uniprotkb:A6NC20|uniprotkb:Q8WTS9|uniprotkb:Q9P0X0	psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym)	psi-mi:ganab_human(display_long)|uniprotkb:GANAB(gene name)|psi-mi:GANAB(display_short)|uniprotkb:G2AN(gene name synonym)|uniprotkb:KIAA0088(gene name synonym)|uniprotkb:Glucosidase II subunit alpha(gene name synonym)|uniprotkb:Alpha-glucosidase 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771114|imex:IM-28143-62	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N	ensembl:ENSG00000089597(gene)|ensembl:ENST00000356638(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004553"(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006491"(N-glycan processing)|go:"GO:0016020"(membrane)|go:"GO:0017177"(glucosidase II complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0033919"(glucan 1,3-alpha-glucosidase activity)|go:"GO:0042470"(melanosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090599"(alpha-glucosidase activity)|interpro:IPR000322(Glycoside hydrolase, family 31)|interpro:IPR011013(Glycoside hydrolase-type carbohydrate-binding)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR025887|interpro:IPR030458|interpro:IPR030459|mint:Q14697|reactome:R-HSA-532668|reactome:R-HSA-901042|reactome:R-HSA-9694548|reactome:R-HSA-9683686|refseq:NP_938148.1|refseq:NP_938149.2|refseq:NP_001265121.1|refseq:NP_001265122.1|refseq:NP_001265123.1|genbank_nucl_gi:88900491(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606	rogid:663u1GYwNTZrodoVqwzFjSDGCqs9606	rigid:C4TpH/vx6vdJ4LhXeaQzMwUuuys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWF2	uniprotkb:Q9UBV2	intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401	intact:EBI-358766|uniprotkb:Q6UWT6|uniprotkb:Q9P1T9|uniprotkb:Q9UHK7|ensembl:ENSP00000337053	psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym)	psi-mi:se1l1_human(display_long)|uniprotkb:SEL1L(gene name)|psi-mi:SEL1L(display_short)|uniprotkb:TSA305(gene name synonym)|uniprotkb:UNQ128/PRO1063(orf name)|uniprotkb:Suppressor of lin-12-like protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771114|imex:IM-28143-62	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N	refseq:NP_001231913.1|refseq:NP_005056.3|ensembl:ENSG00000071537(gene)|ensembl:ENST00000336735(transcript)|go:"GO:0000836"(Hrd1p ubiquitin ligase complex)|go:"GO:0000839"(Hrd1p ubiquitin ligase ERAD-L complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009306"(protein secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0050821"(protein stabilization)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR006597(Sel1-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|mint:Q9UBV2|reactome:R-HSA-1912420|reactome:R-HSA-382556|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-901032|dip:DIP-46259N|genbank_nucl_gi:62512184(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606	rogid:eufE+8nfcHK8CDl+AQ5G+3NtL+09606	rigid:C4TpH/vx6vdJ4LhXeaQzMwUuuys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWF2	uniprotkb:Q9NUP9	intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401	intact:EBI-1171517|ensembl:ENSP00000278193	psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym)	psi-mi:lin7c_human(display_long)|uniprotkb:Mammalian lin-seven protein 3(gene name synonym)|uniprotkb:Vertebrate lin-7 homolog 3(gene name synonym)|uniprotkb:LIN7C(gene name)|psi-mi:LIN7C(display_short)|uniprotkb:MALS3(gene name synonym)|uniprotkb:VELI3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771114|imex:IM-28143-62	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N	refseq:NP_060832.1|ensembl:ENSG00000148943(gene)|ensembl:ENST00000278193(transcript)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006887"(exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0098793"(presynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR014775(L27, C-terminal)|interpro:IPR017365(Lin-7 homologue)|interpro:IPR036034|interpro:IPR036892|mint:Q9NUP9|rcsb pdb:3LRA|reactome:R-HSA-212676|reactome:R-HSA-6794361|reactome:R-HSA-9609736|genbank_nucl_gi:59798474(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606	rogid:F2rasaJ64Olc9qScN79LJRqsUEE9606	rigid:C4TpH/vx6vdJ4LhXeaQzMwUuuys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWF2	uniprotkb:P27824	intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401	intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000421434|ensembl:ENSP00000421813|ensembl:ENSP00000424063|ensembl:ENSP00000424745|ensembl:ENSP00000491760|ensembl:ENSP00000492372|ensembl:ENSP00000492868|ensembl:ENSP00000505013|ensembl:ENSP00000505202|ensembl:ENSP00000505526|ensembl:ENSP00000505960|ensembl:ENSP00000506003|ensembl:ENSP00000506021|ensembl:ENSP00000506061|ensembl:ENSP00000506078|ensembl:ENSP00000506509|ensembl:ENSP00000506568|ensembl:ENSP00000506583|ensembl:ENSP00000247461|ensembl:ENSP00000391646|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3	psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym)	psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771114|imex:IM-28143-62	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N	refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|go:"GO:0099059"(integral component of presynaptic active zone membrane)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|ensembl:ENST00000452673(transcript)|ensembl:ENST00000502296(transcript)|ensembl:ENST00000504734(transcript)|ensembl:ENST00000509563(transcript)|ensembl:ENST00000513246(transcript)|ensembl:ENST00000638425(transcript)|ensembl:ENST00000638706(transcript)|ensembl:ENST00000639938(transcript)|ensembl:ENST00000680013(transcript)|ensembl:ENST00000680042(transcript)|ensembl:ENST00000680092(transcript)|ensembl:ENST00000680618(transcript)|ensembl:ENST00000681072(transcript)|ensembl:ENST00000681168(transcript)|ensembl:ENST00000681476(transcript)|ensembl:ENST00000681674(transcript)|ensembl:ENST00000681712(transcript)|ensembl:ENST00000681733(transcript)|ensembl:ENST00000681903(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|ensembl:ENST00000247461(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0006457"(protein folding)|go:"GO:0007568"(aging)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|ensembl:ENSG00000127022(gene)|ensembl:ENSG00000283777(gene)|dip:DIP-457N|genbank_nucl_gi:543920(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606	rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606	rigid:C4TpH/vx6vdJ4LhXeaQzMwUuuys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWF2	uniprotkb:P63267	intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401	intact:EBI-297795|uniprotkb:P12718|uniprotkb:Q504R1|uniprotkb:Q6FI22|ensembl:ENSP00000295137|ensembl:ENSP00000386857|uniprotkb:B2R7E7|uniprotkb:D6W5H8|uniprotkb:B4E315|uniprotkb:E9PG30	psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym)	psi-mi:acth_human(display_long)|uniprotkb:ACTG2(gene name)|psi-mi:ACTG2(display_short)|uniprotkb:ACTA3(gene name synonym)|uniprotkb:ACTSG(gene name synonym)|uniprotkb:Smooth muscle gamma-actin(gene name synonym)|uniprotkb:Gamma-2-actin(gene name synonym)|uniprotkb:Alpha-actin-3(gene name synonym)|uniprotkb:ACTL3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771114|imex:IM-28143-62	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N	go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0032982"(myosin filament)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0072562"(blood microparticle)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:6JAT|reactome:R-HSA-445355|go:"GO:0010628"(positive regulation of gene expression)|ensembl:ENST00000345517(transcript)|ensembl:ENST00000409624(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|ensembl:ENSG00000163017(gene)|refseq:NP_001186822.1|refseq:NP_001606.1|genbank_nucl_gi:54036679(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606	rogid:tp0JsXhrGsRl5i4Wg2dyaPGUPxA9606	rigid:C4TpH/vx6vdJ4LhXeaQzMwUuuys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWF2	uniprotkb:P27635	intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401	intact:EBI-352398|uniprotkb:A3KQT0|uniprotkb:Q16470|uniprotkb:Q2HXT7|uniprotkb:Q53FH7|uniprotkb:Q6FGN8|uniprotkb:Q8TDA5|intact:EBI-3046680|uniprotkb:D3DWW6|ensembl:ENSP00000341730|ensembl:ENSP00000358832	psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym)	psi-mi:rl10_human(display_long)|uniprotkb:RPL10(gene name)|psi-mi:RPL10(display_short)|uniprotkb:QM(gene name synonym)|uniprotkb:Protein QM(gene name synonym)|uniprotkb:Tumor suppressor QM(gene name synonym)|uniprotkb:Laminin receptor homolog(gene name synonym)|uniprotkb:DXS648E(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL16(gene name synonym)|uniprotkb:Ribosomal protein L10(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771114|imex:IM-28143-62	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N	refseq:NP_001243506.2|refseq:NP_001243509.2|refseq:NP_001290553.1|refseq:NP_001290554.1|refseq:NP_001290555.1|ensembl:ENSG00000147403(gene)|ensembl:ENST00000344746(transcript)|ensembl:ENST00000369817(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|refseq:NP_006004.3|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045182"(translation regulator activity)|go:"GO:1990403"(embryonic brain development)|interpro:IPR001197(Ribosomal protein L10e)|interpro:IPR016180(Ribosomal protein L10e/L16)|interpro:IPR018255|interpro:IPR036920|mint:P27635|rcsb pdb:2PA2|rcsb pdb:5AJ0|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6W6L|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|go:"GO:0016020"(membrane)|reactome:R-HSA-975957|dip:DIP-1133N|genbank_nucl_gi:223890243(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606	rogid:wJnBcv39yvVz2CaZq8UKgxIpJeE9606	rigid:C4TpH/vx6vdJ4LhXeaQzMwUuuys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWF2	uniprotkb:O14936	intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401	intact:EBI-1215506|uniprotkb:Q5VT18|uniprotkb:Q5VT19|uniprotkb:Q66T42|uniprotkb:A6NES1|uniprotkb:O43215|uniprotkb:Q17RI4|uniprotkb:Q59HA0|uniprotkb:Q5VT16|uniprotkb:Q5VT17|uniprotkb:Q9BYH6|uniprotkb:Q9NYB2|uniprotkb:Q9NYB3|uniprotkb:B7ZKY0|ensembl:ENSP00000367405	psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym)	psi-mi:cskp_human(display_long)|uniprotkb:CASK(gene name)|psi-mi:CASK(display_short)|uniprotkb:LIN2(gene name synonym)|uniprotkb:Calcium/calmodulin-dependent serine protein kinase(gene name synonym)|uniprotkb:Protein lin-2 homolog(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771114|imex:IM-28143-62	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N	refseq:NP_001119526.1|refseq:NP_001119527.1|refseq:NP_003679.2|dip:DIP-38727N|ensembl:ENSG00000147044(gene)|ensembl:ENST00000378163(transcript)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031982"(vesicle)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060170"(ciliary membrane)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0070509"(calcium ion import)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0090288"(negative regulation of cellular response to growth factor stimulus)|rcsb pdb:3MFT|rcsb pdb:3MFU|rcsb pdb:3TAC|rcsb pdb:6KMH|rcsb pdb:7OAI|rcsb pdb:7OAJ|rcsb pdb:7OAK|rcsb pdb:7OAL|reactome:R-HSA-212676|reactome:R-HSA-3000170|reactome:R-HSA-373753|reactome:R-HSA-6794361|reactome:R-HSA-9609736|reactome:R-HSA-9662360|reactome:R-HSA-9662361|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014775(L27, C-terminal)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035473|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:O14936|rcsb pdb:1KGD|rcsb pdb:1KWA|rcsb pdb:1ZL8|rcsb pdb:3C0G|rcsb pdb:3C0H|rcsb pdb:3C0I|rcsb pdb:3MFR|rcsb pdb:3MFS|genbank_nucl_gi:186700627(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606	rogid:zTaBgQexJON3EVgJq9FHjf+aSCY9606	rigid:C4TpH/vx6vdJ4LhXeaQzMwUuuys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWF2	uniprotkb:Q9BPW8	intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401	intact:EBI-307125|uniprotkb:O43800|uniprotkb:B2RAY3|ensembl:ENSP00000216121	psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym)	psi-mi:nips1_human(display_long)|uniprotkb:NIPSNAP1(gene name)|psi-mi:NIPSNAP1(display_short)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771114|imex:IM-28143-62	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N	refseq:NP_001189431.1|refseq:NP_003625.2|ensembl:ENSG00000184117(gene)|ensembl:ENST00000216121(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0097060"(synaptic membrane)|interpro:IPR011008(Dimeric alpha-beta barrel)|interpro:IPR012577(NIPSNAP)|mint:Q9BPW8|genbank_nucl_gi:17380144(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606	rogid:mOosuRNhEeYvVB5cUbkMzTJ7X7s9606	rigid:C4TpH/vx6vdJ4LhXeaQzMwUuuys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWF2	uniprotkb:P51570	intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401	intact:EBI-2269932|uniprotkb:B2RC07|intact:EBI-6190170|uniprotkb:B4E1G6|ensembl:ENSP00000225614|ensembl:ENSP00000465930	psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym)	psi-mi:galk1_human(display_long)|uniprotkb:GALK1(gene name)|psi-mi:GALK1(display_short)|uniprotkb:GALK(gene name synonym)|uniprotkb:Galactose kinase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771114|imex:IM-28143-62	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N	go:"GO:0019388"(galactose catabolic process)|go:"GO:0019402"(galactitol metabolic process)|go:"GO:0061623"(glycolytic process from galactose)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000705(Galactokinase)|interpro:IPR006203(GHMP kinase, ATP-binding, conserved site)|interpro:IPR006204(GHMP kinase)|interpro:IPR006206(Mevalonate and galactokinase)|interpro:IPR013750(GHMP kinase, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR019539|interpro:IPR019741|interpro:IPR020568|interpro:IPR036554|mint:P51570|ensembl:ENSG00000108479(gene)|ensembl:ENST00000225614(transcript)|ensembl:ENST00000588479(transcript)|go:"GO:0004335"(galactokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005534"(galactose binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0016020"(membrane)|rcsb pdb:1WUU|rcsb pdb:1YH7|rcsb pdb:6GR2|rcsb pdb:6Q3W|rcsb pdb:6Q3X|rcsb pdb:6Q8Z|rcsb pdb:6Q90|rcsb pdb:6Q91|rcsb pdb:6QJE|rcsb pdb:6ZFH|rcsb pdb:6ZGV|rcsb pdb:6ZGW|rcsb pdb:6ZGX|rcsb pdb:6ZGY|rcsb pdb:6ZGZ|reactome:R-HSA-5609976|reactome:R-HSA-70370|genbank_nucl_gi:1730187(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606	rogid:TtFcTQq+nspsst+xInA/huo/ZbU9606	rigid:C4TpH/vx6vdJ4LhXeaQzMwUuuys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWF2	uniprotkb:P50402	intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401	intact:EBI-489887|uniprotkb:Q6FI02|ensembl:ENSP00000358857|ensembl:ENSP00000507533	psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym)	psi-mi:emd_human(display_long)|uniprotkb:EDMD(gene name synonym)|uniprotkb:STA(gene name synonym)|uniprotkb:EMD(gene name)|psi-mi:EMD(display_short)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771114|imex:IM-28143-62	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N	refseq:NP_000108.1|ensembl:ENSP00000358857|ensembl:ENSP00000507533|ensembl:ENSG00000102119(gene)|ensembl:ENST00000369842(transcript)|ensembl:ENST00000683627(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR011015(LEM-like fold)|interpro:IPR034989|interpro:IPR035004|mint:P50402|rcsb pdb:1JEI|rcsb pdb:2ODC|rcsb pdb:2ODG|rcsb pdb:6GHD|rcsb pdb:6RPR|rcsb pdb:7NDY|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609523|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|dip:DIP-34638N|genbank_nucl_gi:1706639(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606	rogid:hqH2sFjAGwjIGtGX/rjVVFgaYsE9606	rigid:C4TpH/vx6vdJ4LhXeaQzMwUuuys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWF2	uniprotkb:Q9C005	intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401	intact:EBI-744973|uniprotkb:D6W578|ensembl:ENSP00000295066|ensembl:ENSP00000345837	psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym)	psi-mi:dpy30_human(display_long)|uniprotkb:DPY30(gene name)|psi-mi:DPY30(display_short)|uniprotkb:Dpy-30-like protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771114|imex:IM-28143-62	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N	refseq:NP_115963.1|ensembl:ENSG00000162961(gene)|ensembl:ENST00000295066(transcript)|ensembl:ENST00000342166(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006348"|go:"GO:0016197"(endosomal transport)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|mint:Q9C005|rcsb pdb:3G36|rcsb pdb:4RIQ|rcsb pdb:4RT4|rcsb pdb:4RTA|rcsb pdb:6E2H|rcsb pdb:6PWV|reactome:R-HSA-3214841|reactome:R-HSA-8936459|refseq:NP_001308138.1|dip:DIP-34476N|genbank_nucl_gi:14916555(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606	rogid:yC9NJhTfEIT+YyfWRSJLGbRsQkc9606	rigid:C4TpH/vx6vdJ4LhXeaQzMwUuuys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWF2	uniprotkb:P21796	intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401	intact:EBI-354158|uniprotkb:Q5FVE7|uniprotkb:Q9UIQ5|uniprotkb:Q9UPL0|uniprotkb:B3KVK4|uniprotkb:D3DQ93|ensembl:ENSP00000265333|ensembl:ENSP00000378484|ensembl:ENSP00000378487	psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym)	psi-mi:vdac1_human(display_long)|uniprotkb:VDAC1(gene name)|psi-mi:VDAC1(display_short)|uniprotkb:VDAC(gene name synonym)|uniprotkb:Outer mitochondrial membrane protein porin 1(gene name synonym)|uniprotkb:Plasmalemmal porin(gene name synonym)|uniprotkb:Porin 31HL(gene name synonym)|uniprotkb:Porin 31HM(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771114|imex:IM-28143-62	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N	refseq:NP_003365.1|refseq:XP_005272132.1|refseq:XP_016865310.1|refseq:XP_016865311.1|refseq:XP_016865312.1|dip:DIP-32862N|ensembl:ENSG00000213585(gene)|ensembl:ENST00000265333(transcript)|ensembl:ENST00000395044(transcript)|ensembl:ENST00000395047(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006820"(anion transport)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007612"(learning)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046930"(pore complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097001"(ceramide binding)|go:"GO:0110099"(negative regulation of calcium import into the mitochondrion)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030270|mint:P21796|rcsb pdb:2JK4|rcsb pdb:2K4T|rcsb pdb:5JDP|rcsb pdb:5XDN|rcsb pdb:5XDO|rcsb pdb:6G6U|rcsb pdb:6G73|rcsb pdb:6TIQ|rcsb pdb:6TIR|reactome:R-HSA-1268020|reactome:R-HSA-5205685|reactome:R-HSA-5689880|reactome:R-HSA-70268|reactome:R-HSA-8949215|genbank_nucl_gi:130683(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606	rogid:8Fqe6Ga3NmwwuICa4L45ga2i1nk9606	rigid:C4TpH/vx6vdJ4LhXeaQzMwUuuys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8IWF2	uniprotkb:Q9P2K2	intact:EBI-10763361|uniprotkb:B2RDI4|uniprotkb:Q8N378|uniprotkb:Q96BD1|uniprotkb:Q9H5L5|uniprotkb:Q9H6M8|ensembl:ENSP00000216187|ensembl:ENSP00000380400|ensembl:ENSP00000380401	intact:EBI-11126467|uniprotkb:Q9H9W7|uniprotkb:A7E260|uniprotkb:A7MD07|uniprotkb:B9EH67|uniprotkb:A5PKW9|ensembl:ENSP00000281741	psi-mi:fxrd2_human(display_long)|uniprotkb:Endoplasmic reticulum flavoprotein associated with degradation(gene name synonym)|uniprotkb:FOXRED2(gene name)|psi-mi:FOXRED2(display_short)|uniprotkb:ERFAD(gene name synonym)	psi-mi:txd16_human(display_long)|uniprotkb:TXNDC16(gene name)|psi-mi:TXNDC16(display_short)|uniprotkb:KIAA1344(gene name synonym)|uniprotkb:ERP90(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771114|imex:IM-28143-62	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001095841.1|refseq:NP_079231.4|ensembl:ENSG00000100350(gene)|ensembl:ENST00000216187(transcript)|ensembl:ENST00000397223(transcript)|ensembl:ENST00000397224(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR036188|dip:DIP-48946N	refseq:NP_001153519.1|refseq:NP_065835.2|ensembl:ENSG00000087301(gene)|ensembl:ENST00000281741(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR040090|genbank_nucl_gi:117949599(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:rZ4tKHGgxYdUAaFjXW+4qTisPzs9606	rogid:zzfV8NEefGI6L0ra5Z/bEg3WfEU9606	rigid:C4TpH/vx6vdJ4LhXeaQzMwUuuys	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96IV0	uniprotkb:Q96IV0	intact:EBI-6165879|ensembl:ENSP00000280700|uniprotkb:B4DJE9|uniprotkb:Q59FB1|uniprotkb:Q6PJD8|uniprotkb:Q9BVR8|uniprotkb:Q9NR70	intact:EBI-6165879|ensembl:ENSP00000280700|uniprotkb:B4DJE9|uniprotkb:Q59FB1|uniprotkb:Q6PJD8|uniprotkb:Q9BVR8|uniprotkb:Q9NR70	psi-mi:ngly1_human(display_long)|uniprotkb:NGLY1(gene name)|psi-mi:NGLY1(display_short)|uniprotkb:N-glycanase 1(gene name synonym)|uniprotkb:PNG1(gene name synonym)|uniprotkb:"Peptide:N-glycanase"(gene name synonym)	psi-mi:ngly1_human(display_long)|uniprotkb:NGLY1(gene name)|psi-mi:NGLY1(display_short)|uniprotkb:N-glycanase 1(gene name synonym)|uniprotkb:PNG1(gene name synonym)|uniprotkb:"Peptide:N-glycanase"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771306|imex:IM-28143-116	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000151092(gene)|ensembl:ENST00000280700(transcript)|go:"GO:0000224"("peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006517"(protein deglycosylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|interpro:IPR002931(Transglutaminase-like)|interpro:IPR006588(Protein of unknown function PAW)|interpro:IPR008979(Galactose-binding like)|interpro:IPR018997|interpro:IPR036339|interpro:IPR038680|interpro:IPR038765|mint:Q96IV0|rcsb pdb:2CCQ|rcsb pdb:2CM0|reactome:R-HSA-532668|refseq:NP_001138767.1|refseq:NP_060767.2|refseq:NP_001138765.1|refseq:NP_001138766.1	ensembl:ENSG00000151092(gene)|ensembl:ENST00000280700(transcript)|go:"GO:0000224"("peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006517"(protein deglycosylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|interpro:IPR002931(Transglutaminase-like)|interpro:IPR006588(Protein of unknown function PAW)|interpro:IPR008979(Galactose-binding like)|interpro:IPR018997|interpro:IPR036339|interpro:IPR038680|interpro:IPR038765|mint:Q96IV0|rcsb pdb:2CCQ|rcsb pdb:2CM0|reactome:R-HSA-532668|refseq:NP_001138767.1|refseq:NP_060767.2|refseq:NP_001138765.1|refseq:NP_001138766.1|genbank_nucl_gi:114152093(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:CujOKLkvqxGmWpFvJM3B894PHqc9606	rogid:CujOKLkvqxGmWpFvJM3B894PHqc9606	rigid:TCZoC/QtCWph3IyqpstrAijxMTQ	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96IV0	uniprotkb:P55072	intact:EBI-6165879|ensembl:ENSP00000280700|uniprotkb:B4DJE9|uniprotkb:Q59FB1|uniprotkb:Q6PJD8|uniprotkb:Q9BVR8|uniprotkb:Q9NR70	intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777	psi-mi:ngly1_human(display_long)|uniprotkb:NGLY1(gene name)|psi-mi:NGLY1(display_short)|uniprotkb:N-glycanase 1(gene name synonym)|uniprotkb:PNG1(gene name synonym)|uniprotkb:"Peptide:N-glycanase"(gene name synonym)	psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771306|imex:IM-28143-116	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000151092(gene)|ensembl:ENST00000280700(transcript)|go:"GO:0000224"("peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006517"(protein deglycosylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|interpro:IPR002931(Transglutaminase-like)|interpro:IPR006588(Protein of unknown function PAW)|interpro:IPR008979(Galactose-binding like)|interpro:IPR018997|interpro:IPR036339|interpro:IPR038680|interpro:IPR038765|mint:Q96IV0|rcsb pdb:2CCQ|rcsb pdb:2CM0|reactome:R-HSA-532668|refseq:NP_001138767.1|refseq:NP_060767.2|refseq:NP_001138765.1|refseq:NP_001138766.1	refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N|genbank_nucl_gi:6094447(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:CujOKLkvqxGmWpFvJM3B894PHqc9606	rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606	rigid:TCZoC/QtCWph3IyqpstrAijxMTQ	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96IV0	uniprotkb:P54727	intact:EBI-6165879|ensembl:ENSP00000280700|uniprotkb:B4DJE9|uniprotkb:Q59FB1|uniprotkb:Q6PJD8|uniprotkb:Q9BVR8|uniprotkb:Q9NR70	intact:EBI-954531|uniprotkb:Q8WUB0|uniprotkb:B3KWK8|ensembl:ENSP00000350708|uniprotkb:G5E9P0|uniprotkb:Q7Z5K8	psi-mi:ngly1_human(display_long)|uniprotkb:NGLY1(gene name)|psi-mi:NGLY1(display_short)|uniprotkb:N-glycanase 1(gene name synonym)|uniprotkb:PNG1(gene name synonym)|uniprotkb:"Peptide:N-glycanase"(gene name synonym)	psi-mi:rd23b_human(display_long)|uniprotkb:XP-C repair-complementing complex 58 kDa protein(gene name synonym)|uniprotkb:RAD23B(gene name)|psi-mi:RAD23B(display_short)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771306|imex:IM-28143-116	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000151092(gene)|ensembl:ENST00000280700(transcript)|go:"GO:0000224"("peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0006517"(protein deglycosylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|interpro:IPR002931(Transglutaminase-like)|interpro:IPR006588(Protein of unknown function PAW)|interpro:IPR008979(Galactose-binding like)|interpro:IPR018997|interpro:IPR036339|interpro:IPR038680|interpro:IPR038765|mint:Q96IV0|rcsb pdb:2CCQ|rcsb pdb:2CM0|reactome:R-HSA-532668|refseq:NP_001138767.1|refseq:NP_060767.2|refseq:NP_001138765.1|refseq:NP_001138766.1	refseq:NP_002865.1|refseq:NP_001231653.1|ensembl:ENSG00000119318(gene)|ensembl:ENST00000358015(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR036353|interpro:IPR041811|mint:P54727|rcsb pdb:1P1A|rcsb pdb:1PVE|rcsb pdb:1UEL|reactome:R-HSA-532668|reactome:R-HSA-5689877|reactome:R-HSA-5696394|reactome:R-HSA-5696395|interpro:IPR029071|dip:DIP-39944N|genbank_nucl_gi:1709985(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2020/08/14	rogid:CujOKLkvqxGmWpFvJM3B894PHqc9606	rogid:msyh4+G2TzDW+xgGjixPKWWrjRE9606	rigid:TCZoC/QtCWph3IyqpstrAijxMTQ	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:Q01484	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-941975|uniprotkb:Q01485|uniprotkb:Q08AC7|uniprotkb:Q08AC8|uniprotkb:Q7Z3L5|ensembl:ENSP00000349588	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:ank2_human(display_long)|uniprotkb:ANKB(gene name synonym)|uniprotkb:ANK2(gene name)|psi-mi:ANK2(display_short)|uniprotkb:Brain ankyrin(gene name synonym)|uniprotkb:Ankyrin-B(gene name synonym)|uniprotkb:Non-erythroid ankyrin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771384|imex:IM-28143-66	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	refseq:NP_001120965.1|refseq:NP_001139.3|refseq:NP_066187.2|dip:DIP-37425N|ensembl:ENSG00000145362(gene)|ensembl:ENST00000357077(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003283"(atrial septum development)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006897"(endocytosis)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030507"(spectrin binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030913"(paranodal junction assembly)|go:"GO:0031430"(M band)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031672"(A band)|go:"GO:0033292"(T-tubule organization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034613"(cellular protein localization)|go:"GO:0036309"(protein localization to M-band)|go:"GO:0036371"(protein localization to T-tubule)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043034"(costamere)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051597"(response to methylmercury)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086015"(SA node cell action potential)|go:"GO:0086046"(membrane depolarization during SA node cell action potential)|go:"GO:0086066"(atrial cardiac muscle cell to AV node cell communication)|go:"GO:0086070"(SA node cell to atrial cardiac muscle cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0140031"(phosphorylation-dependent protein binding)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901021"(positive regulation of calcium ion transmembrane transporter activity)|go:"GO:2001259"(positive regulation of cation channel activity)|interpro:IPR000488(Death)|interpro:IPR000906(ZU5)|interpro:IPR002110(Ankyrin)|interpro:IPR011029(DEATH-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR040745|mint:Q01484|rcsb pdb:4D8O|rcsb pdb:4RLV|rcsb pdb:4RLY|rcsb pdb:5Y4D|rcsb pdb:5Y4E|rcsb pdb:5Y4F|rcsb pdb:5YIR|rcsb pdb:5YIS|rcsb pdb:6KZJ|rcsb pdb:6M3Q|reactome:R-HSA-445095|reactome:R-HSA-6807878|genbank_nucl_gi:1703310(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:wHoFDw3CIP2xOUZj9WzEMGm/z8k9606	rigid:mcJzgn5rqR/TFNV6emc8qDtu1HI	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:O96005	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-2873194|ensembl:ENSP00000336994|uniprotkb:Q53ET6|uniprotkb:Q9BSS5|uniprotkb:B3KQH2|uniprotkb:B4DDS3|uniprotkb:B4E2X9|uniprotkb:B7Z9X9|uniprotkb:F5H8J3	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:clpt1_human(display_long)|uniprotkb:CLPTM1(gene name)|psi-mi:CLPTM1(display_short)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771384|imex:IM-28143-66	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	ensembl:ENSG00000104853(gene)|ensembl:ENST00000337392(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007275"(multicellular organism development)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0033081"(regulation of T cell differentiation in thymus)|interpro:IPR008429(Cleft lip and palate transmembrane 1)|interpro:IPR030434|mint:O96005|refseq:NP_001285.1|refseq:NP_001269104.1|refseq:NP_001269105.1|genbank_nucl_gi:74735596(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:CFQ2o5QzCYtIDaxlVtJlA6FEMgU9606	rigid:mcJzgn5rqR/TFNV6emc8qDtu1HI	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:Q9BTV4	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-721293|uniprotkb:Q7L4N5|uniprotkb:Q8NC30|uniprotkb:Q96A63|uniprotkb:Q96F19|uniprotkb:Q96JX0|uniprotkb:Q9H076|ensembl:ENSP00000303992	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:tmm43_human(display_long)|uniprotkb:TMEM43(gene name)|psi-mi:TMEM43(display_short)|uniprotkb:UNQ2564/PRO6244(orf name)|uniprotkb:Protein LUMA(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771384|imex:IM-28143-66	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	refseq:NP_077310.1|ensembl:ENSG00000170876(gene)|ensembl:ENST00000306077(transcript)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0071763"(nuclear membrane organization)|interpro:IPR012430(Protein of unknown function DUF1625)|genbank_nucl_gi:74733151(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:8VCyVNtrzh7J9uJ2EjQLBhJGrfc9606	rigid:mcJzgn5rqR/TFNV6emc8qDtu1HI	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:Q96CS3	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771384|imex:IM-28143-66	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N|genbank_nucl_gi:74731375(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606	rigid:mcJzgn5rqR/TFNV6emc8qDtu1HI	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:P40855	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-594747|uniprotkb:Q8NI97|intact:EBI-981972|uniprotkb:Q5QNY4|uniprotkb:D3DVE7|ensembl:ENSP00000357051	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:pex19_human(display_long)|uniprotkb:PEX19(gene name)|psi-mi:PEX19(display_short)|uniprotkb:HK33(gene name synonym)|uniprotkb:PXF(gene name synonym)|uniprotkb:OK/SW-cl.22(orf name)|uniprotkb:Peroxin-19(gene name synonym)|uniprotkb:Peroxisomal farnesylated protein(gene name synonym)|uniprotkb:33 kDa housekeeping protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771384|imex:IM-28143-66	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	refseq:NP_001180573.1|refseq:NP_002848.1|dip:DIP-24172N|ensembl:ENSG00000162735(gene)|ensembl:ENST00000368072(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006625"(protein targeting to peroxisome)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016557"(peroxisome membrane biogenesis)|go:"GO:0016559"(peroxisome fission)|go:"GO:0031526"(brush border membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033328"(peroxisome membrane targeting sequence binding)|go:"GO:0036105"(peroxisome membrane class-1 targeting sequence binding)|go:"GO:0045046"(protein import into peroxisome membrane)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0072663"(establishment of protein localization to peroxisome)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:1900131"(negative regulation of lipid binding)|interpro:IPR006708(Pex19 protein)|interpro:IPR038322|mint:P40855|rcsb pdb:2W85|rcsb pdb:2WL8|rcsb pdb:3AJB|rcsb pdb:3MK4|rcsb pdb:5LNF|reactome:R-HSA-1369062|reactome:R-HSA-9603798|genbank_nucl_gi:729723(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:yNnX2hPPJ7miGaz2Req0qFn0L189606	rigid:mcJzgn5rqR/TFNV6emc8qDtu1HI	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:Q9P0I2	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-1054670|uniprotkb:Q53GH8|uniprotkb:Q6ZMC2|uniprotkb:B2R4Z9|ensembl:ENSP00000245046	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:emc3_human(display_long)|uniprotkb:EMC3(gene name)|psi-mi:EMC3(display_short)|uniprotkb:TMEM111(gene name synonym)|uniprotkb:Transmembrane protein 111(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771384|imex:IM-28143-66	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	refseq:NP_060917.1|ensembl:ENSG00000125037(gene)|ensembl:ENST00000245046(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008568(Protein of unknown function DUF850, transmembrane eukaryotic)|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-8980692|genbank_nucl_gi:71153383(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:VbIl0nFhcDMIPTxmBclaIMtbVU09606	rigid:mcJzgn5rqR/TFNV6emc8qDtu1HI	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:O75477	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-359299|uniprotkb:B0QZ42|uniprotkb:Q53HV0|ensembl:ENSP00000384900|ensembl:ENSP00000410964|intact:EBI-21351077|uniprotkb:D3DR65	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:erln1_human(display_long)|uniprotkb:KEO4(gene name synonym)|uniprotkb:ERLIN1(gene name)|psi-mi:ERLIN1(display_short)|uniprotkb:C10orf69(gene name synonym)|uniprotkb:KE04(gene name synonym)|uniprotkb:SPFH1(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 1(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1(gene name synonym)|uniprotkb:Protein KE04(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771384|imex:IM-28143-66	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	refseq:NP_001094096.1|refseq:NP_006450.2|ensembl:ENSG00000107566(gene)|ensembl:ENST00000407654(transcript)|ensembl:ENST00000421367(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O75477|reactome:R-HSA-382556|reactome:R-HSA-5678895|refseq:NP_001334786.1|refseq:NP_001334788.1|refseq:NP_001334789.1|refseq:NP_001334790.1|genbank_nucl_gi:67461552(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:HycFhL5qL5GLmaIIc9NtTcBbu1M9606	rigid:mcJzgn5rqR/TFNV6emc8qDtu1HI	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:Q92616	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-356221|ensembl:ENSP00000300648|uniprotkb:O95001|uniprotkb:O95651|uniprotkb:Q6P2S3|uniprotkb:Q86X65|uniprotkb:Q8N5I5|uniprotkb:Q8WU80|uniprotkb:Q99736|uniprotkb:Q9UE60|uniprotkb:A8KAY1|intact:EBI-1058692	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:gcn1_human(display_long)|uniprotkb:GCN1(gene name)|psi-mi:GCN1(display_short)|uniprotkb:GCN1 eIF-2-alpha kinase activator homolog(gene name synonym)|uniprotkb:GCN1-like protein 1(gene name synonym)|uniprotkb:GCN1L1(gene name synonym)|uniprotkb:General control of amino-acid synthesis 1-like protein 1(gene name synonym)|uniprotkb:KIAA0219(gene name synonym)|uniprotkb:Translational activator GCN1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771384|imex:IM-28143-66	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	ensembl:ENSG00000089154(gene)|ensembl:ENST00000300648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0043022"(ribosome binding)|go:"GO:0045296"(cadherin binding)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR033173|interpro:IPR034085|mint:Q92616|reactome:R-HSA-9633012|go:"GO:0005844"(polysome)|refseq:NP_006827.1|genbank_nucl_gi:60390211(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:NtSEW6xjvCkUyb40cnk0JdL5PcA9606	rigid:mcJzgn5rqR/TFNV6emc8qDtu1HI	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:Q71U36	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771384|imex:IM-28143-66	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|genbank_nucl_gi:55977864(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606	rigid:mcJzgn5rqR/TFNV6emc8qDtu1HI	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:Q9BVK6	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-1056827|uniprotkb:Q8WZ61|uniprotkb:Q14437|ensembl:ENSP00000330945	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:tmed9_human(display_long)|uniprotkb:TMED9(gene name)|psi-mi:TMED9(display_short)|uniprotkb:GP25L2(gene name synonym)|uniprotkb:Glycoprotein 25L2(gene name synonym)|uniprotkb:p25(gene name synonym)|uniprotkb:p24 family protein alpha-2(gene name synonym)|uniprotkb:GMP25(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771384|imex:IM-28143-66	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	refseq:NP_059980.2|ensembl:ENSG00000184840(gene)|ensembl:ENST00000332598(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|mint:Q9BVK6|reactome:R-HSA-6807878|reactome:R-HSA-6811434|genbank_nucl_gi:39725636(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:z5YDyY6mtnc4WGWU9G9sNgp+Ga09606	rigid:mcJzgn5rqR/TFNV6emc8qDtu1HI	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:O94905	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-4400770|uniprotkb:A0JLQ1|uniprotkb:A8K5S9|uniprotkb:B4DM38|uniprotkb:D3DSW0|uniprotkb:Q6NW21|uniprotkb:Q86VS6|uniprotkb:Q86W49|ensembl:ENSP00000428112	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:erln2_human(display_long)|uniprotkb:ERLIN2(gene name)|psi-mi:ERLIN2(display_short)|uniprotkb:C8orf2(gene name synonym)|uniprotkb:SPFH2(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 2(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2(gene name synonym)|uniprotkb:UNQ2441/PRO5003/PRO9924(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771384|imex:IM-28143-66	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	refseq:NP_001003790.1|refseq:NP_001003791.1|refseq:NP_009106.1|refseq:XP_016868489.1|refseq:XP_005273449.1|ensembl:ENSG00000147475(gene)|ensembl:ENST00000519638(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045121"(membrane raft)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:O94905|reactome:R-HSA-382556|reactome:R-HSA-5655302|reactome:R-HSA-5678895|reactome:R-HSA-8853336|genbank_nucl_gi:38257366(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:Evjg3G0FFeQ499BNlJxpK6t8to89606	rigid:mcJzgn5rqR/TFNV6emc8qDtu1HI	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:O14686	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-996065|uniprotkb:O14687|intact:EBI-28986759|ensembl:ENSP00000301067	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:kmt2d_human(display_long)|uniprotkb:KMT2D(gene name)|psi-mi:KMT2D(display_short)|uniprotkb:ALL1-related protein(gene name synonym)|uniprotkb:ALR(gene name synonym)|uniprotkb:MLL2(gene name synonym)|uniprotkb:MLL4(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771384|imex:IM-28143-66	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	refseq:NP_003473.3|refseq:XP_006719677.1|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0043627"(response to estrogen)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:1904837"(beta-catenin-TCF complex assembly)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR009071(High mobility group box, HMG)|ensembl:ENSG00000167548(gene)|ensembl:ENST00000301067(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001555"(oocyte growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|interpro:IPR036910|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR037890|interpro:IPR041961|interpro:IPR041964|mint:O14686|rcsb pdb:3UVK|rcsb pdb:4ERQ|rcsb pdb:4Z4P|rcsb pdb:6O7G|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR034732|ensembl:ENSP00000301067|refseq:XP_005269219.1|dip:DIP-37875N|genbank_nucl_gi:37999860(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:eaCGHR6OqxzL66VYfOrzBWJApHY9606	rigid:mcJzgn5rqR/TFNV6emc8qDtu1HI	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:Q9UKV5	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771384|imex:IM-28143-66	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N|genbank_nucl_gi:34922250(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rigid:mcJzgn5rqR/TFNV6emc8qDtu1HI	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:Q15006	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-359031|uniprotkb:Q8WUE1|ensembl:ENSP00000220853	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:emc2_human(display_long)|uniprotkb:EMC2(gene name)|psi-mi:EMC2(display_short)|uniprotkb:KIAA0103(gene name synonym)|uniprotkb:TTC35(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 35(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771384|imex:IM-28143-66	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	refseq:NP_055488.1|ensembl:ENSG00000104412(gene)|ensembl:ENST00000220853(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039856|mint:Q15006|rcsb pdb:6WW7|rcsb pdb:6Y4L|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|genbank_nucl_gi:3183217(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:HMRmqsVdjJybM/A4VCzAFbGsHu09606	rigid:mcJzgn5rqR/TFNV6emc8qDtu1HI	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:Q8TCT9	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-347472|uniprotkb:Q540H8|uniprotkb:Q5JWP2|uniprotkb:Q5JWP3|uniprotkb:Q5JWP4|uniprotkb:Q5JWP5|uniprotkb:Q7Z4F2|uniprotkb:Q86Y35|uniprotkb:Q95H87|uniprotkb:Q9H110|uniprotkb:Q9H111|uniprotkb:Q15K36|uniprotkb:B2RAY5|uniprotkb:E1P5L3|ensembl:ENSP00000343032	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:hm13_human(display_long)|uniprotkb:HM13(gene name)|psi-mi:HM13(display_short)|uniprotkb:H13(gene name synonym)|uniprotkb:PSL3(gene name synonym)|uniprotkb:SPP(gene name synonym)|uniprotkb:Signal peptide peptidase(gene name synonym)|uniprotkb:Presenilin-like protein 3(gene name synonym)|uniprotkb:Intramembrane protease 1(gene name synonym)|uniprotkb:IMP1(gene name synonym)|uniprotkb:MSTP086(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771384|imex:IM-28143-66	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	refseq:NP_110416.1|refseq:NP_848695.1|refseq:NP_848696.1|refseq:NP_848697.1|ensembl:ENSG00000101294(gene)|ensembl:ENST00000340852(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006465"(signal peptide processing)|go:"GO:0008233"(peptidase activity)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033619"(membrane protein proteolysis)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042500"(aspartic endopeptidase activity, intramembrane cleaving)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0061960"(regulation of heme oxygenase activity)|go:"GO:0071458"(integral component of cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:1904211"(membrane protein proteolysis involved in retrograde protein transport, ER to cytosol)|interpro:IPR006639(Peptidase A22, presenilin signal peptide)|interpro:IPR007369(Peptidase A22B, signal peptide peptidase)|reactome:R-HSA-9707587|genbank_nucl_gi:25008563(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:DxNjJDcc+zomfXAj0TEaByKeNqc9606	rigid:mcJzgn5rqR/TFNV6emc8qDtu1HI	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:P27635	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-352398|uniprotkb:A3KQT0|uniprotkb:Q16470|uniprotkb:Q2HXT7|uniprotkb:Q53FH7|uniprotkb:Q6FGN8|uniprotkb:Q8TDA5|intact:EBI-3046680|uniprotkb:D3DWW6|ensembl:ENSP00000341730|ensembl:ENSP00000358832	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:rl10_human(display_long)|uniprotkb:RPL10(gene name)|psi-mi:RPL10(display_short)|uniprotkb:QM(gene name synonym)|uniprotkb:Protein QM(gene name synonym)|uniprotkb:Tumor suppressor QM(gene name synonym)|uniprotkb:Laminin receptor homolog(gene name synonym)|uniprotkb:DXS648E(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL16(gene name synonym)|uniprotkb:Ribosomal protein L10(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771384|imex:IM-28143-66	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	refseq:NP_001243506.2|refseq:NP_001243509.2|refseq:NP_001290553.1|refseq:NP_001290554.1|refseq:NP_001290555.1|ensembl:ENSG00000147403(gene)|ensembl:ENST00000344746(transcript)|ensembl:ENST00000369817(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|refseq:NP_006004.3|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045182"(translation regulator activity)|go:"GO:1990403"(embryonic brain development)|interpro:IPR001197(Ribosomal protein L10e)|interpro:IPR016180(Ribosomal protein L10e/L16)|interpro:IPR018255|interpro:IPR036920|mint:P27635|rcsb pdb:2PA2|rcsb pdb:5AJ0|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6W6L|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|go:"GO:0016020"(membrane)|reactome:R-HSA-975957|dip:DIP-1133N|genbank_nucl_gi:223890243(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:wJnBcv39yvVz2CaZq8UKgxIpJeE9606	rigid:mcJzgn5rqR/TFNV6emc8qDtu1HI	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:P51149	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-1056089|uniprotkb:A8K3V6|uniprotkb:Q9NWJ0|uniprotkb:Q9UPB0|ensembl:ENSP00000265062|ensembl:ENSP00000501618|ensembl:ENSP00000502000|ensembl:ENSP00000502088|ensembl:ENSP00000502486	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:rab7a_human(display_long)|uniprotkb:RAB7A(gene name)|psi-mi:RAB7A(display_short)|uniprotkb:RAB7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771384|imex:IM-28143-66	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	refseq:NP_004628.4|ensembl:ENSG00000075785(gene)|ensembl:ENST00000265062(transcript)|ensembl:ENST00000674589(transcript)|ensembl:ENST00000675342(transcript)|ensembl:ENST00000675497(transcript)|ensembl:ENST00000676214(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006897"(endocytosis)|go:"GO:0007174"(epidermal growth factor catabolic process)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0019003"(GDP binding)|go:"GO:0019076"(viral release from host cell)|go:"GO:0022615"(protein to membrane docking)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032419"(extrinsic component of lysosome membrane)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0061724"(lipophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090382"(phagosome maturation)|go:"GO:0090383"(phagosome acidification)|go:"GO:0090385"(phagosome-lysosome fusion)|go:"GO:0099638"(endosome to plasma membrane protein transport)|go:"GO:1902586"(obsolete multi-organism intercellular transport)|go:"GO:1903542"(negative regulation of exosomal secretion)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1905366"(negative regulation of intralumenal vesicle formation)|go:"GO:1905394"(retromer complex binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51149|rcsb pdb:1T91|rcsb pdb:1YHN|rcsb pdb:6IYB|rcsb pdb:6WCW|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9636383|reactome:R-HSA-9636569|rcsb pdb:3LAW|dip:DIP-39879N|genbank_nucl_gi:1709999(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:AJbKizzw4zCAn+roRF2Im1Tt4xE9606	rigid:mcJzgn5rqR/TFNV6emc8qDtu1HI	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:P50402	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-489887|uniprotkb:Q6FI02|ensembl:ENSP00000358857|ensembl:ENSP00000507533	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:emd_human(display_long)|uniprotkb:EDMD(gene name synonym)|uniprotkb:STA(gene name synonym)|uniprotkb:EMD(gene name)|psi-mi:EMD(display_short)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771384|imex:IM-28143-66	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	refseq:NP_000108.1|ensembl:ENSP00000358857|ensembl:ENSP00000507533|ensembl:ENSG00000102119(gene)|ensembl:ENST00000369842(transcript)|ensembl:ENST00000683627(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR011015(LEM-like fold)|interpro:IPR034989|interpro:IPR035004|mint:P50402|rcsb pdb:1JEI|rcsb pdb:2ODC|rcsb pdb:2ODG|rcsb pdb:6GHD|rcsb pdb:6RPR|rcsb pdb:7NDY|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609523|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|dip:DIP-34638N|genbank_nucl_gi:1706639(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:hqH2sFjAGwjIGtGX/rjVVFgaYsE9606	rigid:mcJzgn5rqR/TFNV6emc8qDtu1HI	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:Q8TC07	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-1048247|uniprotkb:B9A6L6|intact:EBI-6190229|uniprotkb:B4DMT9|uniprotkb:J3KNI9|uniprotkb:Q9HA83|intact:EBI-28984447|ensembl:ENSP00000448182	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:tbc15_human(display_long)|uniprotkb:TBC1D15(gene name)|psi-mi:TBC1D15(display_short)|uniprotkb:GTPase-activating protein RAB7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771384|imex:IM-28143-66	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	refseq:NP_001139685.2|refseq:NP_001139686.1|refseq:NP_073608.4|ensembl:ENST00000319106|ensembl:ENSP00000318262|ensembl:ENST00000485960|ensembl:ENSP00000420678|ensembl:ENSP00000448182|ensembl:ENSG00000121749(gene)|ensembl:ENST00000550746(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR021935|interpro:IPR035969|reactome:R-HSA-8854214|genbank_nucl_gi:143811467(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:3tlqjLtZ/Bq5H6M00sHIwqNqqw49606	rigid:mcJzgn5rqR/TFNV6emc8qDtu1HI	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:P52272	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-486809|uniprotkb:Q9Y492|uniprotkb:Q15584|uniprotkb:Q8WZ44|uniprotkb:Q96H56|uniprotkb:Q9BWL9|intact:EBI-28985795|ensembl:ENSP00000325376	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:hnrpm_human(display_long)|uniprotkb:HNRNPM(gene name)|psi-mi:HNRNPM(display_short)|uniprotkb:HNRPM(gene name synonym)|uniprotkb:NAGR1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771384|imex:IM-28143-66	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	refseq:NP_005959.2|refseq:NP_112480.2|ensembl:ENSG00000099783(gene)|ensembl:ENST00000325495(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042382"(paraspeckles)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000815"(regulation of mRNA stability involved in response to oxidative stress)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR024666|interpro:IPR024667|interpro:IPR034990|interpro:IPR035979|mint:P52272|rcsb pdb:2DGV|rcsb pdb:2DH9|rcsb pdb:2DO0|rcsb pdb:2OT8|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|dip:DIP-29336N|ensembl:ENSP00000325376|ensembl:ENST00000348943|ensembl:ENSP00000325732|genbank_nucl_gi:14141152(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:5FnCgrz0xltEkgw3yh70KP2jz5g9606	rigid:mcJzgn5rqR/TFNV6emc8qDtu1HI	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:P21796	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-354158|uniprotkb:Q5FVE7|uniprotkb:Q9UIQ5|uniprotkb:Q9UPL0|uniprotkb:B3KVK4|uniprotkb:D3DQ93|ensembl:ENSP00000265333|ensembl:ENSP00000378484|ensembl:ENSP00000378487	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:vdac1_human(display_long)|uniprotkb:VDAC1(gene name)|psi-mi:VDAC1(display_short)|uniprotkb:VDAC(gene name synonym)|uniprotkb:Outer mitochondrial membrane protein porin 1(gene name synonym)|uniprotkb:Plasmalemmal porin(gene name synonym)|uniprotkb:Porin 31HL(gene name synonym)|uniprotkb:Porin 31HM(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771384|imex:IM-28143-66	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	refseq:NP_003365.1|refseq:XP_005272132.1|refseq:XP_016865310.1|refseq:XP_016865311.1|refseq:XP_016865312.1|dip:DIP-32862N|ensembl:ENSG00000213585(gene)|ensembl:ENST00000265333(transcript)|ensembl:ENST00000395044(transcript)|ensembl:ENST00000395047(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006820"(anion transport)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007612"(learning)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046930"(pore complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097001"(ceramide binding)|go:"GO:0110099"(negative regulation of calcium import into the mitochondrion)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030270|mint:P21796|rcsb pdb:2JK4|rcsb pdb:2K4T|rcsb pdb:5JDP|rcsb pdb:5XDN|rcsb pdb:5XDO|rcsb pdb:6G6U|rcsb pdb:6G73|rcsb pdb:6TIQ|rcsb pdb:6TIR|reactome:R-HSA-1268020|reactome:R-HSA-5205685|reactome:R-HSA-5689880|reactome:R-HSA-70268|reactome:R-HSA-8949215|genbank_nucl_gi:130683(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:8Fqe6Ga3NmwwuICa4L45ga2i1nk9606	rigid:mcJzgn5rqR/TFNV6emc8qDtu1HI	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:A0A183YE00	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-6120064	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:a0a183ye00_human(display_long)|uniprotkb:TUB4q(gene name)|psi-mi:TUB4q(display_short)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771384|imex:IM-28143-66	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	interpro:IPR036525|interpro:IPR037103|interpro:IPR023123|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|genbank_nucl_gi:12643363(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:EMEs4Iq1Sb0jVzxy4Zri77EoG249606	rigid:mcJzgn5rqR/TFNV6emc8qDtu1HI	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:Q9NY65	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-356246|ensembl:ENSP00000333326|uniprotkb:B3KPW9|uniprotkb:Q2M3N4|uniprotkb:B2RCX2|uniprotkb:B4DWG3	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:tba8_human(display_long)|uniprotkb:TUBA8(gene name)|psi-mi:TUBA8(display_short)|uniprotkb:TUBAL2(gene name synonym)|uniprotkb:Alpha-tubulin 8(gene name synonym)|uniprotkb:Tubulin alpha chain-like 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771384|imex:IM-28143-66	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_001180343.1|refseq:NP_061816.1|ensembl:ENSG00000183785(gene)|ensembl:ENST00000330423(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5617833|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|dip:DIP-40751N|genbank_nucl_gi:12585376(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:OGRoBAwLchNlK3LtAWkbSbCcxPQ9606	rigid:mcJzgn5rqR/TFNV6emc8qDtu1HI	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:Q9P0L0	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771384|imex:IM-28143-66	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	refseq:NP_003565.4|refseq:NP_919415.2|dip:DIP-41135N|go:"GO:0031982"(vesicle)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|ensembl:ENSG00000101558(gene)|ensembl:ENST00000400000(transcript)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008017"(microtubule binding)|go:"GO:0008219"(cell death)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane)|genbank_nucl_gi:94721250(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606	rigid:mcJzgn5rqR/TFNV6emc8qDtu1HI	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:O75396	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-1058865|ensembl:ENSP00000463393|uniprotkb:A8K1G0	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:sc22b_human(display_long)|uniprotkb:SEC22B(gene name)|psi-mi:SEC22B(display_short)|uniprotkb:SEC22L1(gene name synonym)|uniprotkb:SEC22 vesicle-trafficking protein homolog B(gene name synonym)|uniprotkb:SEC22 vesicle-trafficking protein-like 1(gene name synonym)|uniprotkb:ER-Golgi SNARE of 24 kDa(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771384|imex:IM-28143-66	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	ensembl:ENSG00000265808(gene)|ensembl:ENST00000578049(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042470"(melanosome)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR001388(Synaptobrevin)|interpro:IPR010908(Longin)|interpro:IPR011012(Longin-like)|interpro:IPR042855|interpro:IPR044565|mint:O75396|rcsb pdb:2NUP|rcsb pdb:2NUT|rcsb pdb:3EGD|rcsb pdb:3EGX|refseq:NP_004883.3|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6811434|reactome:R-HSA-1236974|dip:DIP-50458N|genbank_nucl_gi:94429050(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:DRKtD169T9eYZ2kFufLapidvcKs9606	rigid:mcJzgn5rqR/TFNV6emc8qDtu1HI	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:P04844	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-719731|uniprotkb:Q5JYR6|uniprotkb:Q9UBE1|uniprotkb:Q6IBA5|uniprotkb:Q96E21|uniprotkb:Q9BUQ3|ensembl:ENSP00000237530	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:rpn2_human(display_long)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit(gene name synonym)|uniprotkb:Ribophorin-2(gene name synonym)|uniprotkb:Ribophorin II(gene name synonym)|uniprotkb:RIBIIR(gene name synonym)|uniprotkb:RPN2(gene name)|psi-mi:RPN2(display_short)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771384|imex:IM-28143-66	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	refseq:NP_001129243.1|refseq:NP_002942.2|ensembl:ENSG00000118705(gene)|ensembl:ENST00000237530(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0007568"(aging)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0042493"|go:"GO:0043022"(ribosome binding)|interpro:IPR008814(Ribophorin II)|mint:P04844|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-9694548|refseq:NP_001311234.1|refseq:NP_001311235.1|refseq:NP_001311228.1|refseq:NP_001311230.1|refseq:NP_001311231.1|refseq:NP_001311232.1|refseq:NP_001311233.1|genbank_nucl_gi:9297108(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:7bTuuEb3ykWQvkI/5DKpga48s/w9606	rigid:mcJzgn5rqR/TFNV6emc8qDtu1HI	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:Q96AG4	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-358888|uniprotkb:Q9P189|uniprotkb:D3DTX8|ensembl:ENSP00000225972|uniprotkb:B2RE83	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:lrc59_human(display_long)|uniprotkb:LRRC59(gene name)|psi-mi:LRRC59(display_short)|uniprotkb:Ribosome-binding protein p34(gene name synonym)|uniprotkb:PRO1855(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771384|imex:IM-28143-66	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	refseq:NP_060979.2|ensembl:ENSG00000108829(gene)|ensembl:ENST00000225972(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045296"(cadherin binding)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|mint:Q96AG4|genbank_nucl_gi:74760704(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:gAtWed9Jv69oHdkEFgpWGFnvcWE9606	rigid:mcJzgn5rqR/TFNV6emc8qDtu1HI	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:Q8N766	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771384|imex:IM-28143-66	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1|genbank_nucl_gi:74751081(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606	rigid:mcJzgn5rqR/TFNV6emc8qDtu1HI	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8NBM4	uniprotkb:Q5SNT2	intact:EBI-724045|uniprotkb:Q0VAB5|uniprotkb:Q5W0W6|uniprotkb:Q5W0W9|uniprotkb:Q6GQR2|uniprotkb:Q6P4B0|uniprotkb:Q8N2E8|uniprotkb:Q96NW2|uniprotkb:B3KNV7|ensembl:ENSP00000383911	intact:EBI-10986145|ensembl:ENSP00000344503|uniprotkb:Q5SNT3|uniprotkb:B9EH90	psi-mi:ubac2_human(display_long)|uniprotkb:PHGDHL1(gene name synonym)|uniprotkb:Phosphoglycerate dehydrogenase-like protein 1(gene name synonym)|uniprotkb:UBAC2(gene name)|psi-mi:UBAC2(display_short)|uniprotkb:PSEC0110(orf name)	psi-mi:tm201_human(display_long)|uniprotkb:TMEM201(gene name)|psi-mi:TMEM201(display_short)|uniprotkb:NET5(gene name synonym)|uniprotkb:SAMP1(gene name synonym)|uniprotkb:Spindle-associated membrane protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Christianson et al. (2011)	doi:10.1038/ncb2383|imex:IM-28143|pubmed:22119785	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25771384|imex:IM-28143-66	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137544.1|refseq:NP_808882.1|ensembl:ENSG00000134882(gene)|ensembl:ENST00000403766(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR035952|interpro:IPR041928|mint:Q8NBM4|refseq:XP_011519386.1|refseq:XP_006720011.1	refseq:NP_001010866.1|refseq:NP_001124396.2|refseq:XP_011539212.1|ensembl:ENSG00000188807(gene)|ensembl:ENST00000340381(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005521"(lamin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0010761"(fibroblast migration)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051015"(actin filament binding)|go:"GO:0051642"(centrosome localization)|go:"GO:0090435"(protein localization to nuclear envelope)|interpro:IPR018617|interpro:IPR018861|interpro:IPR040041|genbank_nucl_gi:74743441(identity)	-	-	-	figure legend:TableS2A, Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293s)|taxid:9606(Human 293S cell line)	-	2020/06/30	2021/11/30	rogid:wOJ8u9ZDDuqYRij5EjsFm4hLRUQ9606	rogid:YAYQ9viEL2HvpBxeStvJQrQ/z2c9606	rigid:mcJzgn5rqR/TFNV6emc8qDtu1HI	false	s tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)