#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q04651 uniprotkb:P39727 intact:EBI-27850|uniprotkb:E9PAD9|uniprotkb:D6VZA6|ensemblfungi:YML067C intact:EBI-20659|uniprotkb:D6VPH4|ensemblfungi:YAL042W psi-mi:erv41_yeast(display_long)|uniprotkb:YML067C(locus name)|uniprotkb:ERV41(gene name)|psi-mi:ERV41(display_short) psi-mi:erv46_yeast(display_long)|uniprotkb:FUN9(orf name)|uniprotkb:YAL042W(locus name)|uniprotkb:ERV46(gene name)|psi-mi:ERV46(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318094|imex:IM-26944-161 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013644.1|sgd:S000004532|dip:DIP-6791N|mint:Q04651|ensemblfungi:YML067C(gene)|ensemblfungi:YML067C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542|rcsb pdb:3ZLC|ensemblgenomes:YML067C(identity) refseq:NP_009358.1|sgd:S000000040|ensemblfungi:YAL042W(gene)|ensemblfungi:YAL042W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542|dip:DIP-3792N|mint:P39727|ensemblgenomes:YAL042W(identity) - - crc64:FB7BC171B88BB5EA figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:IpGpvBxckHz1ExXTnTsKEHU2su8559292 rogid:tVyaLk7odK7bfnaz1FMv0E9lgtU559292 rigid:RxRVkGV0ee3X9a8C2VOpR6zOqbo false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53176 uniprotkb:P39552 intact:EBI-6205|uniprotkb:D6VU89|ensemblfungi:YGL051W intact:EBI-20785|uniprotkb:D6VPN3|ensemblfungi:YAR033W psi-mi:mst27_yeast(display_long)|uniprotkb:MST27(gene name)|psi-mi:MST27(display_short)|uniprotkb:DUP2(gene name synonym)|uniprotkb:DUP240 protein MST27(gene name synonym)|uniprotkb:YGL051W(locus name) psi-mi:mst28_yeast(display_long)|uniprotkb:MST28(gene name)|psi-mi:MST28(display_short)|uniprotkb:YAR033W(locus name)|uniprotkb:FUN59(orf name)|uniprotkb:DUP240 protein MST28(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318106|imex:IM-26944-261 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003019|refseq:NP_011464.1|dip:DIP-1852N|ensemblfungi:YGL051W(gene)|ensemblfungi:YGL051W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030663"(COPI-coated vesicle membrane)|interpro:IPR001142(Yeast membrane protein DUP)|ensemblgenomes:YGL051W(identity) sgd:S000000079|refseq:NP_009419.1|ensemblfungi:YAR033W(gene)|ensemblfungi:YAR033W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030663"(COPI-coated vesicle membrane)|interpro:IPR001142(Yeast membrane protein DUP)|dip:DIP-1853N|ensemblgenomes:YAR033W(identity) - - crc64:B23AAD4D26831319 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:Vt2rgCK0Q+Ia3/1xU5hD7i+OCvg559292 rogid:7qnoPryvC2NJOfEusnJS0//rzhs559292 rigid:Um3F0fVy2zpQcM18bqOXdh6IUWc false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06169 uniprotkb:P38292 intact:EBI-31008|intact:EBI-937900|uniprotkb:Q66R43|uniprotkb:D6VYW6|ensemblfungi:YLR324W intact:EBI-20873|uniprotkb:D6VQG4|uniprotkb:E9P8W7|ensemblfungi:YBR168W psi-mi:pex30_yeast(display_long)|uniprotkb:PEX30(gene name)|psi-mi:PEX30(display_short)|uniprotkb:Peroxin-30(gene name synonym)|uniprotkb:YLR324W(locus name) psi-mi:pex32_yeast(display_long)|uniprotkb:YBR168W(locus name)|uniprotkb:YBR1220(orf name)|uniprotkb:Peroxin-32(gene name synonym)|uniprotkb:PEX32(gene name)|psi-mi:PEX32(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318130|imex:IM-26944-601 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013428.1|sgd:S000004316|dip:DIP-1800N|mint:Q06169|ensemblfungi:YLR324W(gene)|ensemblfungi:YLR324W_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005933"(cellular bud)|go:"GO:0007031"(peroxisome organization)|go:"GO:0032581"(ER-dependent peroxisome organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071944"(cell periphery)|go:"GO:0097749"(membrane tubulation)|go:"GO:1900063"(regulation of peroxisome organization)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR010482(Integral peroxisomal membrane peroxin)|ensemblgenomes:YLR324W(identity) refseq:NP_009727.3|sgd:S000000372|mint:P38292|ensemblfungi:YBR168W(gene)|ensemblfungi:YBR168W_mRNA(transcript)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR010482(Integral peroxisomal membrane peroxin)|interpro:IPR029953|dip:DIP-5361N|ensemblgenomes:YBR168W(identity) - crc64:417DBE56B1C8B1D5 - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:vkvJ4GqSW60wMG0m3ChlSzwcC3c559292 rogid:DEkpv9G4QcIIVjSPELA0mWW1tIk559292 rigid:xk3uf+LEuYSBM8pt2Bf7y1me1ds false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25376 uniprotkb:P38085 intact:EBI-2357|uniprotkb:D6VQZ1|ensemblfungi:YCL025C intact:EBI-20222|uniprotkb:D6VQ68|ensemblfungi:YBR069C psi-mi:agp1_yeast(display_long)|uniprotkb:AGP1(gene name)|psi-mi:AGP1(display_short)|uniprotkb:YCL025C(locus name)|uniprotkb:YCL25C(orf name)|uniprotkb:Asparagine/glutamine permease(gene name synonym) psi-mi:tat1_yeast(display_long)|uniprotkb:TAT1(gene name)|psi-mi:TAT1(display_short)|uniprotkb:TAP1(gene name synonym)|uniprotkb:VAP1(gene name synonym)|uniprotkb:YBR069C(locus name)|uniprotkb:YBR0710(orf name)|uniprotkb:Tyrosine and tryptophan amino acid transporter 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318118|imex:IM-26944-421 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009905.3|sgd:S000000530|dip:DIP-4973N|mint:P25376|ensemblfungi:YCL025C(gene)|ensemblfungi:YCL025C_mRNA(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015192"(L-phenylalanine transmembrane transporter activity)|go:"GO:0015193"(L-proline transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0098718"(serine import across plasma membrane)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region)|ensemblgenomes:YCL025C(identity) refseq:NP_009625.1|sgd:S000000273|mint:P38085|ensemblfungi:YBR069C(gene)|ensemblfungi:YBR069C_mRNA(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015827"(tryptophan transport)|go:"GO:0015828"(tyrosine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022893"(low-affinity tryptophan transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region)|dip:DIP-4912N|ensemblgenomes:YBR069C(identity) - crc64:8E19A836C2F6C50F crc64:7A575A9BF2A084F8 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:bB5pBnaoMUTwxlz8v5MAjCWc4Mg559292 rogid:J/bUE0sAFk7WkiPOXHMXQHfI618559292 rigid:X/8FCtdFaqViUzLoToVScFfjdjA false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32915 uniprotkb:P38353 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 intact:EBI-18175|uniprotkb:D6VQS8|ensemblfungi:YBR283C psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:ssh1_yeast(display_long)|uniprotkb:SSH1(gene name)|psi-mi:SSH1(display_short)|uniprotkb:Ssh1 complex subunit alpha(gene name synonym)|uniprotkb:Ssh1 complex subunit SSH1(gene name synonym)|uniprotkb:YBR2020(orf name)|uniprotkb:YBR283C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318154|imex:IM-26944-163 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915|ensemblgenomes:YLR378C(identity) refseq:NP_009842.1|sgd:S000000487|ensemblfungi:YBR283C(gene)|ensemblfungi:YBR283C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:2WW9|rcsb pdb:2WWA|dip:DIP-4962N|mint:P38353|ensemblgenomes:YBR283C(identity) - - crc64:48267EEA3E0191BD figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 rogid:76wvZIdv7W5BQn6wI+sHOGQAyuc559292 rigid:B9+rfc4HejFPHcTjrdVwUndp3WM false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40088 uniprotkb:P38310 intact:EBI-7138|uniprotkb:D3DM52|ensemblfungi:YER145C intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W psi-mi:ftr1_yeast(display_long)|uniprotkb:FTR1(gene name)|psi-mi:FTR1(display_short)|uniprotkb:YER145C(locus name) psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318142|imex:IM-26944-81 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-5376N|refseq:NP_011072.1|sgd:S000000947|mint:P40088|ensemblfungi:YER145C(gene)|ensemblfungi:YER145C_mRNA(transcript)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:1901684"(arsenate ion transmembrane transport)|interpro:IPR004923(Iron permease FTR1)|interpro:IPR005217(Conserved hypothetical protein CHP00145)|ensemblgenomes:YER145C(identity) refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1)|ensemblgenomes:YBR207W(identity) - - crc64:7B4E620ABC39A053 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:fhDKp2YYbK7C+ACjHx1AuPCyts4559292 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 rigid:Nru5IGj6UNGc37K7TjbdKi47FUY false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12335 uniprotkb:P25349 intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 intact:EBI-21840|uniprotkb:D6VR14|ensemblfungi:YCR004C psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:ycp4_yeast(display_long)|uniprotkb:YCR042(orf name)|uniprotkb:YCR4C(orf name)|uniprotkb:YCR004C(locus name)|uniprotkb:YCP4(gene name)|psi-mi:YCP4(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318178|imex:IM-26944-603 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N|ensemblgenomes:YDR032C(identity) refseq:NP_009930.1|sgd:S000000597|dip:DIP-1781N|ensemblfungi:YCR004C(gene)|ensemblfungi:YCR004C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|ensemblgenomes:YCR004C(identity) - crc64:1056E7A1F3E82288 - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 rogid:l7d0Z9G9F/3vOnI80MPKdsll1aI559292 rigid:bHXQKmNq5b9C9KtPiDu97Y+U1GU false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01560 uniprotkb:P25555 intact:EBI-12114|uniprotkb:D6VT60|ensemblfungi:YDR432W intact:EBI-7410|uniprotkb:D6VR01|ensemblfungi:YCL011C psi-mi:nop3_yeast(display_long)|uniprotkb:MTR13(gene name synonym)|uniprotkb:MTS1(gene name synonym)|uniprotkb:Mitochondrial targeting suppressor 1 protein(gene name synonym)|uniprotkb:Nuclear polyadenylated RNA-binding protein 1(gene name synonym)|uniprotkb:NPL3(gene name)|psi-mi:NPL3(display_short)|uniprotkb:NAB1(gene name synonym)|uniprotkb:YDR432W(locus name)|uniprotkb:D9461.19(orf name)|uniprotkb:NOP3(gene name synonym) psi-mi:gbp2_yeast(display_long)|uniprotkb:GBP2(gene name)|psi-mi:GBP2(display_short)|uniprotkb:RLF6(gene name synonym)|uniprotkb:YCL011C(locus name)|uniprotkb:YCL11C(orf name)|uniprotkb:RAP1 localization factor 6(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318166|imex:IM-26944-181 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDR432W(gene)|ensemblfungi:YDR432W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006415"(translational termination)|go:"GO:0008143"("poly(A) binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:2000805"("negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034166|interpro:IPR035979|rcsb pdb:2JD5|rcsb pdb:2JVO|rcsb pdb:2JVR|rcsb pdb:2OSQ|rcsb pdb:2OSR|refseq:NP_010720.3|sgd:S000002840|dip:DIP-6464N|ensemblgenomes:YDR432W(identity) refseq:NP_009916.1|sgd:S000000517|ensemblfungi:YCL011C(gene)|ensemblfungi:YCL011C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|mint:P25555|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:1990904"(ribonucleoprotein complex)|dip:DIP-2735N|go:"GO:2000815"(regulation of mRNA stability involved in response to oxidative stress)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:2MZQ|ensemblgenomes:YCL011C(identity) - crc64:024439E4B6578787 crc64:5341D7A0E07F208C figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:R/g8r9x82rdG8AThC5VQcbgY6u4559292 rogid:0fURlZ6JcMWvS0mSxpR2LZ8uDrE559292 rigid:HzTgQU80t2OWIfB4zMWWDkFVXuM false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38426 uniprotkb:P31688 intact:EBI-19448|uniprotkb:D6W087|uniprotkb:Q6B1W2|ensemblfungi:YMR261C intact:EBI-19440|uniprotkb:D6VS60|ensemblfungi:YDR074W psi-mi:tps3_yeast(display_long)|uniprotkb:TPS3(gene name)|psi-mi:TPS3(display_short)|uniprotkb:YMR261C(locus name)|uniprotkb:YM8156.03C(orf name)|uniprotkb:Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 115 kDa subunit(gene name synonym) psi-mi:tps2_yeast(display_long)|uniprotkb:TPS2(gene name)|psi-mi:TPS2(display_short)|uniprotkb:PFK3(gene name synonym)|uniprotkb:YDR074W(locus name)|uniprotkb:YD8554.07(orf name)|uniprotkb:Trehalose-6-phosphate phosphatase(gene name synonym)|uniprotkb:Trehalose synthase complex catalytic subunit TPS2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318202|imex:IM-26944-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013988.1|sgd:S000004874|ensemblfungi:YMR261C(gene)|ensemblfungi:YMR261C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005946"("alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)")|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0016311"(dephosphorylation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR001830(Glycosyl transferase, family 20)|interpro:IPR003337(Trehalose-phosphatase)|interpro:IPR036412|dip:DIP-891N|mint:P38426|ensemblgenomes:YMR261C(identity) refseq:NP_010359.1|sgd:S000002481|ensemblfungi:YDR074W(gene)|ensemblfungi:YDR074W_mRNA(transcript)|go:"GO:0004805"(trehalose-phosphatase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005946"("alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)")|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0070413"(trehalose metabolism in response to stress)|interpro:IPR001830(Glycosyl transferase, family 20)|interpro:IPR003337(Trehalose-phosphatase)|interpro:IPR006379(HAD-superfamily hydrolase, subfamily IIB)|interpro:IPR023214|interpro:IPR036412|dip:DIP-823N|mint:P31688|ensemblgenomes:YDR074W(identity) - - crc64:E349672CCCDA9349 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:aY+Gu2+xxYxfe40pjJ1KTaYbDxM559292 rogid:kfEKVrS0+2MOIcLy9XDHbAdFFCI559292 rigid:dCmfkr5wucCtZPPaTiiHLwdZcdI false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04894 uniprotkb:P25377 intact:EBI-27680|uniprotkb:D6W0E6|ensemblfungi:YMR318C intact:EBI-2347652|uniprotkb:D6VRA5|ensemblfungi:YCR105W psi-mi:adh6_yeast(display_long)|uniprotkb:ADH6(gene name)|psi-mi:ADH6(display_short)|uniprotkb:YMR318C(locus name)|uniprotkb:YM9924.10C(orf name)|uniprotkb:NADP-dependent alcohol dehydrogenase VI(gene name synonym)|uniprotkb:ScADHVI(gene name synonym) psi-mi:adh7_yeast(display_long)|uniprotkb:ADH7(gene name)|psi-mi:ADH7(display_short)|uniprotkb:NADP-dependent alcohol dehydrogenase VII(gene name synonym)|uniprotkb:YCR105W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318190|imex:IM-26944-183 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004937|refseq:NP_014051.3|dip:DIP-6308N|ensemblfungi:YMR318C(gene)|ensemblfungi:YMR318C_mRNA(transcript)|go:"GO:0006066"(alcohol metabolic process)|go:"GO:0006081"(cellular aldehyde metabolic process)|go:"GO:0008106"("alcohol dehydrogenase (NADP+) activity")|go:"GO:0008270"(zinc ion binding)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0033833"("hydroxymethylfurfural reductase (NADH) activity")|go:"GO:0033845"("hydroxymethylfurfural reductase (NADPH) activity")|go:"GO:0033859"(furaldehyde metabolic process)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR036291|rcsb pdb:1PIW|rcsb pdb:1PS0|rcsb pdb:1Q1N|ensemblgenomes:YMR318C(identity) refseq:NP_010030.1|sgd:S000000702|dip:DIP-7661N|mint:P25377|ensemblfungi:YCR105W(gene)|ensemblfungi:YCR105W_mRNA(transcript)|go:"GO:0006066"(alcohol metabolic process)|go:"GO:0008106"("alcohol dehydrogenase (NADP+) activity")|go:"GO:0008270"(zinc ion binding)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR029752|interpro:IPR036291|ensemblgenomes:YCR105W(identity) - crc64:3F785BE0C5ED8CF1 crc64:BFB0E6C5F93D3F07 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:kzlFYzXPLaaojbVGYkA5qWN/ZPA559292 rogid:PGCt+bqhn63vUVgS5IKrrOukXgg559292 rigid:E0+3x8Ro6kWbP5w8MZjFR5oyj5o false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53834 uniprotkb:Q12449 intact:EBI-28288|uniprotkb:D6W0R3|ensemblfungi:YNL281W intact:EBI-37072|uniprotkb:Q02565|uniprotkb:Q7LIE3|uniprotkb:D6VSJ8|ensemblfungi:YDR214W psi-mi:hch1_yeast(display_long)|uniprotkb:HCH1(gene name)|psi-mi:HCH1(display_short)|uniprotkb:YNL281W(locus name)|uniprotkb:N0589(orf name)|uniprotkb:High-copy Hsp90 suppressor protein 1(gene name synonym) psi-mi:aha1_yeast(display_long)|uniprotkb:AHA1(gene name)|psi-mi:AHA1(display_short)|uniprotkb:YDR214W(locus name)|uniprotkb:YD8142.16(orf name)|uniprotkb:YD8142B.06(orf name)|uniprotkb:Activator of Hsp90 ATPase protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318214|imex:IM-26944-83 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014118.1|sgd:S000005225|dip:DIP-4395N|mint:P53834|ensemblfungi:YNL281W(gene)|ensemblfungi:YNL281W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|interpro:IPR015310(Activator of Hsp90 ATPase, N-terminal)|interpro:IPR036338|interpro:IPR039981|ensemblgenomes:YNL281W(identity) sgd:S000002622|refseq:NP_010500.3|mint:Q12449|dip:DIP-1831N|ensemblfungi:YDR214W(gene)|ensemblfungi:YDR214W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|interpro:IPR013538(Activator of Hsp90 ATPase homologue 1-like)|interpro:IPR015310(Activator of Hsp90 ATPase, N-terminal)|interpro:IPR023393|interpro:IPR036338|interpro:IPR039981|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:6XLB|rcsb pdb:6XLD|rcsb pdb:6XLE|rcsb pdb:6XLF|rcsb pdb:6XLG|rcsb pdb:6XLH|ensemblgenomes:YDR214W(identity) - crc64:DAD84DBF9BF5DC9F crc64:06DF6B40EB5050BE figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:f1gS31qqt1jGRycD4GVoWw043Cs559292 rogid:jCVFPwj0+auPVB/BJ/OwlMSBWUM559292 rigid:nqoKmaO6wN6zDqcL88DH8xdb/LY false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P05319 uniprotkb:P02400 intact:EBI-15456|uniprotkb:D6W227|ensemblfungi:YOL039W intact:EBI-15464|uniprotkb:D6VT16|ensemblfungi:YDR382W psi-mi:rla2_yeast(display_long)|uniprotkb:RPP2A(gene name)|psi-mi:RPP2A(display_short)|uniprotkb:L12EIB(gene name synonym)|uniprotkb:RPA2(gene name synonym)|uniprotkb:RPL44(gene name synonym)|uniprotkb:RPLA2(gene name synonym)|uniprotkb:L12eIB(gene name synonym)|uniprotkb:YP2alpha(gene name synonym)|uniprotkb:L44(gene name synonym)|uniprotkb:YOL039W(locus name)|uniprotkb:Large ribosomal subunit protein P2-A(gene name synonym) psi-mi:rla4_yeast(display_long)|uniprotkb:RPP2B(gene name)|psi-mi:RPP2B(display_short)|uniprotkb:L12EIA(gene name synonym)|uniprotkb:RPL45(gene name synonym)|uniprotkb:RPLA4(gene name synonym)|uniprotkb:L12eIA(gene name synonym)|uniprotkb:YP2beta(gene name synonym)|uniprotkb:L45(gene name synonym)|uniprotkb:YL44C(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:YDR382W(locus name)|uniprotkb:Large ribosomal subunit protein P2-B(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318226|imex:IM-26944-85 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014603.1|sgd:S000005399|ensemblfungi:YOL039W(gene)|ensemblfungi:YOL039W_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002182"(cytoplasmic translational elongation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030295"(protein kinase activator activity)|interpro:IPR027534|interpro:IPR038716|interpro:IPR044076|rcsb pdb:4V6I|dip:DIP-2506N|ensemblgenomes:YOL039W(identity) sgd:S000002790|reactome:R-SCE-156827|reactome:R-SCE-1799339|reactome:R-SCE-72689|reactome:R-SCE-72706|reactome:R-SCE-975956|reactome:R-SCE-975957|refseq:NP_010670.3|ensemblfungi:YDR382W(gene)|ensemblfungi:YDR382W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002182"(cytoplasmic translational elongation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0045860"(positive regulation of protein kinase activity)|interpro:IPR027534|interpro:IPR038716|interpro:IPR044076|rcsb pdb:3N2D|rcsb pdb:3N3X|dip:DIP-580N|ensemblgenomes:YDR382W(identity) - - crc64:EC45406CB5F199F4 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:bvmZbhGsNuMJEdAv9ac1wD6Y+Rs559292 rogid:dvY8zJb/i5nIRnNekgTQdY9Novs559292 rigid:UhwAY+TyMb9nYVug9e2Fm27cgKw false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14359 uniprotkb:P56508 intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C intact:EBI-22135|uniprotkb:D6VTE7|ensemblfungi:YDR525W-A psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:sna2_yeast(display_long)|uniprotkb:YDR525BW(orf name)|uniprotkb:YDR525W-A(locus name)|uniprotkb:SNA2(gene name)|psi-mi:SNA2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318238|imex:IM-26944-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD|ensemblgenomes:YJL151C(identity) refseq:NP_010814.1|sgd:S000007236|interpro:IPR000612(Protein of unknown function UPF0057)|ensemblfungi:YDR525W-A(gene)|ensemblfungi:YDR525W-A_mRNA(transcript)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|ensemblgenomes:YDR525W-A(identity) - crc64:DBA26AF5B769C02A - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 rogid:zqjXp3iXSEELPlEPJCNgQgsCr+o559292 rigid:ZAcX49Pzwa7p12g3YyDqWCWtYwI false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P13586 uniprotkb:P38929 intact:EBI-3091|uniprotkb:D6VTY5|ensemblfungi:YGL167C intact:EBI-3097|uniprotkb:D6VUD2|ensemblfungi:YGL006W psi-mi:atc1_yeast(display_long)|uniprotkb:PMR1(gene name)|psi-mi:PMR1(display_short)|uniprotkb:BSD1(gene name synonym)|uniprotkb:SCC1(gene name synonym)|uniprotkb:YGL167C(locus name)|uniprotkb:G1666(orf name)|uniprotkb:Bypass SOD defects protein 1(gene name synonym)|uniprotkb:"Golgi Ca(2+)-ATPase"(gene name synonym) psi-mi:atc2_yeast(display_long)|uniprotkb:PMC1(gene name)|psi-mi:PMC1(display_short)|uniprotkb:"Vacuolar Ca(2+)-ATPase"(gene name synonym)|uniprotkb:YGL006W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318250|imex:IM-26944-87 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011348.1|sgd:S000003135|dip:DIP-7899N|mint:P13586|ensemblfungi:YGL167C(gene)|ensemblfungi:YGL167C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006828"(manganese ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0015410"(ABC-type manganese transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030026"(cellular manganese ion homeostasis)|go:"GO:0070588"(calcium ion transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006413(Calcium-transporting P-type ATPase, PMR1-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-936837|ensemblgenomes:YGL167C(identity) refseq:NP_011509.1|sgd:S000002974|dip:DIP-5901N|mint:P38929|ensemblfungi:YGL006W(gene)|ensemblfungi:YGL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-418359|reactome:R-SCE-5578775|reactome:R-SCE-936837|ensemblgenomes:YGL006W(identity) - - crc64:5BD9ECFF8508F396 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:FUAnYBfq0rUKxq1wSTgwAx7W6yA559292 rogid:pvI8E79lFI1hRPK/jgugzIH5LI0559292 rigid:NRaZPg+UXoZDRJOUlPKdx3cbjUU false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12436 uniprotkb:P32804 intact:EBI-36677|uniprotkb:D6VYC5|ensemblfungi:YLR130C intact:EBI-29677|uniprotkb:D6VV80|ensemblfungi:YGL255W psi-mi:zrt2_yeast(display_long)|uniprotkb:ZRT2(gene name)|psi-mi:ZRT2(display_short)|uniprotkb:YLR130C(locus name)|uniprotkb:L9606.9(orf name)|uniprotkb:L3120(orf name)|uniprotkb:Low-affinity zinc transport protein ZRT2(gene name synonym) psi-mi:zrt1_yeast(display_long)|uniprotkb:High-affinity zinc transport protein ZRT1(gene name synonym)|uniprotkb:ZRT1(gene name)|psi-mi:ZRT1(display_short)|uniprotkb:YGL255W(locus name)|uniprotkb:NRC376(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318262|imex:IM-26944-89 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013231.1|sgd:S000004120|dip:DIP-2924N|ensemblfungi:YLR130C(gene)|ensemblfungi:YLR130C_mRNA(transcript)|go:"GO:0000007"(low-affinity zinc ion transmembrane transporter activity)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071577"(zinc ion transmembrane transport)|go:"GO:0071578"(zinc ion import across plasma membrane)|interpro:IPR003689(Zinc/iron permease)|interpro:IPR004698(Zinc/iron permease, fungal and plant)|ensemblgenomes:YLR130C(identity) refseq:NP_011259.1|sgd:S000003224|interpro:IPR003689(Zinc/iron permease)|interpro:IPR004698(Zinc/iron permease, fungal and plant)|mint:P32804|ensemblfungi:YGL255W(gene)|ensemblfungi:YGL255W_mRNA(transcript)|go:"GO:0000006"(high-affinity zinc transmembrane transporter activity)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0071577"(zinc ion transmembrane transport)|go:"GO:0071578"(zinc ion import across plasma membrane)|go:"GO:0071944"(cell periphery)|ensemblgenomes:YGL255W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:aHv+Gj0O1owdhsVMGqhNpcm+L3U559292 rogid:O+iQXV9JDMwMi4oLx4yZp/DYdIM559292 rigid:m0muTNqd/yOrOujZfSJIHqugeYo false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06103 uniprotkb:P53235 intact:EBI-8973|ensemblfungi:YOR361C|uniprotkb:D6W356 intact:EBI-23172|uniprotkb:D6VUI9|uniprotkb:Q45U32|ensemblfungi:YGR054W psi-mi:eif3b_yeast(display_long)|uniprotkb:YOR361C(locus name)|uniprotkb:PRT1(gene name)|psi-mi:PRT1(display_short)|uniprotkb:CDC63(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 90 kDa subunit(gene name synonym)|uniprotkb:Translation initiation factor eIF3 p90 subunit(gene name synonym)|uniprotkb:Cell cycle regulation and translation initiation protein(gene name synonym) psi-mi:eif2a_yeast(display_long)|uniprotkb:YGR054W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318274|imex:IM-26944-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR361C(gene)|ensemblfungi:YOR361C_mRNA(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043614"(multi-eIF complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR011400(Translation initiation factor eIF-3b)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR034363|interpro:IPR035979|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:3NS5|rcsb pdb:3NS6|rcsb pdb:3ZWL|rcsb pdb:4U1E|rcsb pdb:4U1F|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6ZCE|rcsb pdb:6ZU9|reactome:R-SCE-156827|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|refseq:NP_015006.3|sgd:S000005888|mint:P06103|dip:DIP-2519N|ensemblgenomes:YOR361C(identity) sgd:S000003286|refseq:NP_011568.3|dip:DIP-5518N|mint:P53235|ensemblfungi:YGR054W(gene)|ensemblfungi:YGR054W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0006413"(translational initiation)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|interpro:IPR011387(Translation initiation factor eIF-2A)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|ensemblgenomes:YGR054W(identity) - crc64:F5E4E783408EE948 crc64:F3C2E78504D83418 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:KeOY80g2TW3axiQNc1iJhsqEUPM559292 rogid:x8zDCH5W5GusC7qYd0mDATXhGVI559292 rigid:oiKVP+X6b1csKg94+npxD4lo38Q false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P16862 uniprotkb:P16861 intact:EBI-9435|ensemblfungi:YMR205C|uniprotkb:D6W030 intact:EBI-9428|ensemblfungi:YGR240C|uniprotkb:D6VV20 psi-mi:pfka2_yeast(display_long)|uniprotkb:PFK2(gene name)|psi-mi:PFK2(display_short)|uniprotkb:YMR205C(locus name)|uniprotkb:YM8325.06C(orf name)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:ATP-dependent 6-phosphofructokinase(gene name synonym) psi-mi:pfka1_yeast(display_long)|uniprotkb:PFK1(gene name)|psi-mi:PFK1(display_short)|uniprotkb:YGR240C(locus name)|uniprotkb:G8599(orf name)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:ATP-dependent 6-phosphofructokinase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318310|imex:IM-26944-185 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR205C(gene)|ensemblfungi:YMR205C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005945"(6-phosphofructokinase complex)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016208"(AMP binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070072"(vacuolar proton-transporting V-type ATPase complex assembly)|go:"GO:0070095"(fructose-6-phosphate binding)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000023(Phosphofructokinase)|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR022953|interpro:IPR029068|interpro:IPR035966|rcsb pdb:3O8O|reactome:R-SCE-6798695|reactome:R-SCE-70171|refseq:NP_013932.1|sgd:S000004818|mint:P16862|dip:DIP-2619N|ensemblgenomes:YMR205C(identity) refseq:NP_011756.1|sgd:S000003472|ensemblfungi:YGR240C(gene)|ensemblfungi:YGR240C_mRNA(transcript)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005945"(6-phosphofructokinase complex)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0016208"(AMP binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070095"(fructose-6-phosphate binding)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000023(Phosphofructokinase)|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR022953|interpro:IPR035966|interpro:IPR040712|rcsb pdb:3O8O|reactome:R-SCE-6798695|reactome:R-SCE-70171|mint:P16861|dip:DIP-1505N|ensemblgenomes:YGR240C(identity) - crc64:82CE6402CEDBBCB2 crc64:995B3DF7C7781B29 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:PurR+sy8cBMAoGxl0dMMcxuz8wI559292 rogid:mqqXE8Cvcp019pDQsU01zBYUsCc559292 rigid:YztK6VVRt09yLhYY9LvzXnu5ov0 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q00582 uniprotkb:P53290 intact:EBI-7954|uniprotkb:D6W0G3|ensemblfungi:YML121W intact:EBI-7962|uniprotkb:D6VUU7|ensemblfungi:YGR163W psi-mi:gtr1_yeast(display_long)|uniprotkb:YM7056.05(orf name)|uniprotkb:YML121W(locus name)|uniprotkb:GTR1(gene name)|psi-mi:GTR1(display_short) psi-mi:gtr2_yeast(display_long)|uniprotkb:YGR163W(locus name)|uniprotkb:GTR2(gene name)|psi-mi:GTR2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318298|imex:IM-26944-605 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013585.1|sgd:S000004590|mint:Q00582|dip:DIP-1358N|ensemblfungi:YML121W(gene)|ensemblfungi:YML121W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006348"|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990131"(Gtr1-Gtr2 GTPase complex)|interpro:IPR006762(Gtr1/RagA G protein)|interpro:IPR027417|interpro:IPR039397|rcsb pdb:3R7W|rcsb pdb:4ARZ|rcsb pdb:6JWP|reactome:R-SCE-165159|reactome:R-SCE-9639288|ensemblgenomes:YML121W(identity) sgd:S000003395|refseq:NP_011679.3|mint:P53290|dip:DIP-4521N|ensemblfungi:YGR163W(gene)|ensemblfungi:YGR163W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000785"(chromatin)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990131"(Gtr1-Gtr2 GTPase complex)|interpro:IPR006762(Gtr1/RagA G protein)|interpro:IPR027417|interpro:IPR039400|rcsb pdb:3R7W|rcsb pdb:4ARZ|rcsb pdb:6JWP|reactome:R-SCE-165159|reactome:R-SCE-9639288|ensemblgenomes:YGR163W(identity) - crc64:B79CE7FE7AD2FDBE crc64:0A0D16C81F73184D figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:5LJU5zMF4NDDY9Bmndu0Q+JIm54559292 rogid:+b9bPvzin/YUc5fOZZVCcFu/GEM559292 rigid:LVXxv4cLIEbNVWFQnXnwzP/YAus false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41948 uniprotkb:P40260 intact:EBI-10721|ensemblfungi:YNL142W|uniprotkb:D6W140 intact:EBI-10714|ensemblfungi:YGR121C|uniprotkb:D6VUQ2 psi-mi:mep2_yeast(display_long)|uniprotkb:MEP2(gene name)|psi-mi:MEP2(display_short)|uniprotkb:YNL142W(locus name)|uniprotkb:N1207(orf name)|uniprotkb:N1820(orf name)|uniprotkb:AMT2(gene name synonym) psi-mi:mep1_yeast(display_long)|uniprotkb:MEP1(gene name)|psi-mi:MEP1(display_short)|uniprotkb:YGR121C(locus name)|uniprotkb:G6331(orf name)|uniprotkb:AMT1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318286|imex:IM-26944-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL142W(gene)|ensemblfungi:YNL142W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|go:"GO:1900430"(positive regulation of filamentous growth of a population of unicellular organisms)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|rcsb pdb:5AEX|refseq:NP_014257.1|sgd:S000005086|dip:DIP-4340N|ensemblgenomes:YNL142W(identity) ensemblfungi:YGR121C(gene)|ensemblfungi:YGR121C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|sgd:S000003353|refseq:NP_011636.3|mint:P40260|dip:DIP-5530N|ensemblgenomes:YGR121C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:3UqhhEzAfYLfblLgaIyu9opa9RI559292 rogid:VnoBl5jhQD24N0SbCLv68HCwl1U559292 rigid:NjHR+x1gFffiXta3L9g64SVe3lg false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53198 uniprotkb:Q05359 intact:EBI-2058104|uniprotkb:D6VUD6|uniprotkb:E9P916|ensemblfungi:YGL002W intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A psi-mi:erp6_yeast(display_long)|uniprotkb:ERP6(gene name)|psi-mi:ERP6(display_short)|uniprotkb:YGL002W(locus name) psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318346|imex:IM-26944-423 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011513.1|sgd:S000002970|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|mint:P53198|ensemblfungi:YGL002W(gene)|ensemblfungi:YGL002W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|reactome:R-SCE-6811434|ensemblgenomes:YGL002W(identity) refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434|ensemblgenomes:YAR002C-A(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:pM23btPgVfhIqmxeV0jxQGSX4/8559292 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 rigid:q0/7fyhKzf+QajF3J70ErU0L76E false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P22202 uniprotkb:P09435 intact:EBI-8621|uniprotkb:D3DM10|ensemblfungi:YER103W intact:EBI-8611|uniprotkb:P18862|uniprotkb:D6VPS7|ensemblfungi:YBL075C psi-mi:hsp74_yeast(display_long)|uniprotkb:YER103W(locus name)|uniprotkb:SSA4(gene name)|psi-mi:SSA4(display_short) psi-mi:hsp73_yeast(display_long)|uniprotkb:YBL06.07(orf name)|uniprotkb:YBL0610(orf name)|uniprotkb:YBL075C(locus name)|uniprotkb:SSA3(gene name)|psi-mi:SSA3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318358|imex:IM-26944-91 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000905|refseq:NP_011029.3|mint:P22202|dip:DIP-3916N|ensemblfungi:YER103W(gene)|ensemblfungi:YER103W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:3UPV|ensemblgenomes:YER103W(identity) refseq:NP_009478.1|sgd:S000000171|mint:P09435|dip:DIP-2266N|ensemblfungi:YBL075C(gene)|ensemblfungi:YBL075C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|ensemblgenomes:YBL075C(identity) - crc64:7A976357AC35C352 crc64:F4B136759B7D4636 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:QiL3U6hhfGX8ulZBYuNAL68zI2s559292 rogid:u3ayjvFHnVNMMrDZdrB7NWaGzBg559292 rigid:kjYO+blRqrPGswWxiGuT609FGak false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23254 uniprotkb:P33315 intact:EBI-19291|uniprotkb:D6W478|ensemblfungi:YPR074C intact:EBI-19297|uniprotkb:D6VQB5|ensemblfungi:YBR117C psi-mi:tkt1_yeast(display_long)|uniprotkb:YP9499.29C(orf name)|uniprotkb:YPR074C(locus name)|uniprotkb:TKL1(gene name)|psi-mi:TKL1(display_short) psi-mi:tkt2_yeast(display_long)|uniprotkb:YBR0912(orf name)|uniprotkb:YBR117C(locus name)|uniprotkb:TKL2(gene name)|psi-mi:TKL2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318370|imex:IM-26944-263 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015399.1|sgd:S000006278|interpro:IPR029061|interpro:IPR033247|interpro:IPR033248|rcsb pdb:1AY0|rcsb pdb:1GPU|rcsb pdb:1NGS|rcsb pdb:1TKA|rcsb pdb:1TKB|rcsb pdb:1TKC|rcsb pdb:1TRK|interpro:IPR020826|ensemblfungi:YPR074C(gene)|ensemblfungi:YPR074C_mRNA(transcript)|go:"GO:0004802"(transketolase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0046872"(metal ion binding)|interpro:IPR005474(Transketolase, N-terminal)|interpro:IPR005475(Transketolase, central region)|interpro:IPR005478(Bacterial transketolase)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|dip:DIP-6765N|mint:P23254|ensemblgenomes:YPR074C(identity) sgd:S000000321|ensemblfungi:YBR117C(gene)|ensemblfungi:YBR117C_mRNA(transcript)|go:"GO:0004802"(transketolase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0046872"(metal ion binding)|interpro:IPR005474(Transketolase, N-terminal)|interpro:IPR005475(Transketolase, central region)|interpro:IPR005478(Bacterial transketolase)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR020826|interpro:IPR029061|interpro:IPR033247|interpro:IPR033248|refseq:NP_009675.3|dip:DIP-757N|mint:P33315|ensemblgenomes:YBR117C(identity) - crc64:40225EAA23A63835 - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:rRfdYF2q76Mp6FJzwkOGeefxbOQ559292 rogid:Sjs+DFWJRPK+Xd6PoO/CHVNniVE559292 rigid:94pv+/yqRIUvAnGY7Hv23ZLXGjw false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O13516 uniprotkb:P05755 intact:EBI-16176|ensemblfungi:YPL081W|uniprotkb:D6W3T6 intact:EBI-16181|ensemblfungi:YBR189W|uniprotkb:D6VQI4 psi-mi:rs9a_yeast(display_long)|uniprotkb:RPS9A(gene name)|psi-mi:RPS9A(display_short)|uniprotkb:RPS13A(gene name synonym)|uniprotkb:YS11A(gene name synonym)|uniprotkb:YPL081W(locus name)|uniprotkb:S13(gene name synonym)|uniprotkb:YS11(gene name synonym)|uniprotkb:RP21(gene name synonym)|uniprotkb:YP28(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS4-A(gene name synonym) psi-mi:rs9b_yeast(display_long)|uniprotkb:RPS9B(gene name)|psi-mi:RPS9B(display_short)|uniprotkb:RPS13B(gene name synonym)|uniprotkb:SUP46(gene name synonym)|uniprotkb:YBR189W(locus name)|uniprotkb:YBR1317(orf name)|uniprotkb:S13(gene name synonym)|uniprotkb:YS11(gene name synonym)|uniprotkb:RP21(gene name synonym)|uniprotkb:YP28(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS4-B(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318382|imex:IM-26944-93 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL081W(gene)|ensemblfungi:YPL081W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0019843"(rRNA binding)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0045903"(positive regulation of translational fidelity)|rcsb pdb:1K5X|rcsb pdb:3J6X|rcsb pdb:3J6Y|rcsb pdb:3J78|rcsb pdb:4U3M|rcsb pdb:4U3N|rcsb pdb:4U3U|rcsb pdb:4U4N|rcsb pdb:4U4O|rcsb pdb:4U4Q|rcsb pdb:4U4R|rcsb pdb:4U4U|rcsb pdb:4U4Y|rcsb pdb:4U4Z|rcsb pdb:4U50|rcsb pdb:4U51|rcsb pdb:4U52|rcsb pdb:4U53|rcsb pdb:3J77|rcsb pdb:4U55|rcsb pdb:4U56|rcsb pdb:4U6F|rcsb pdb:6Z6K|rcsb pdb:6ZCE|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:6ZQG|rcsb pdb:6ZU9|rcsb pdb:6ZVI|rcsb pdb:7A1G|rcsb pdb:7AJT|rcsb pdb:7AJU|rcsb pdb:7B7D|rcsb pdb:7NRC|rcsb pdb:7NRD|rcsb pdb:4V6I|rcsb pdb:4V7R|rcsb pdb:4V88|rcsb pdb:4V8Y|rcsb pdb:4V8Z|rcsb pdb:4V92|rcsb pdb:5DAT|rcsb pdb:5DC3|rcsb pdb:5DGE|rcsb pdb:5DGF|rcsb pdb:5DGV|rcsb pdb:5FCI|rcsb pdb:5FCJ|rcsb pdb:5I4L|rcsb pdb:5JPQ|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:5LL6|rcsb pdb:4V4B|rcsb pdb:5LYB|rcsb pdb:5M1J|rcsb pdb:5MC6|rcsb pdb:5MEI|rcsb pdb:5NDG|rcsb pdb:5NDV|rcsb pdb:5NDW|rcsb pdb:5OBM|rcsb pdb:5ON6|rcsb pdb:5TBW|rcsb pdb:5TGA|rcsb pdb:5TGM|rcsb pdb:5TZS|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6EML|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6Q8Y|rcsb pdb:6RBD|rcsb pdb:6RBE|rcsb pdb:6S47|rcsb pdb:6SNT|rcsb pdb:6SV4|rcsb pdb:6FAI|rcsb pdb:6T4Q|rcsb pdb:6T7I|rcsb pdb:6GQ1|rcsb pdb:6T7T|rcsb pdb:6T83|rcsb pdb:6GQB|rcsb pdb:6GQV|rcsb pdb:6HHQ|rcsb pdb:6I7O|rcsb pdb:6KE6|rcsb pdb:6TB3|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6TNU|rcsb pdb:6WDR|rcsb pdb:6XIQ|rcsb pdb:6XIR|rcsb pdb:6Y7C|rcsb pdb:6Z6J|refseq:NP_015244.1|sgd:S000006002|interpro:IPR022801|interpro:IPR005710(Ribosomal protein S4/S9, eukaryotic/archaeal)|interpro:IPR001912(Ribosomal protein S4)|interpro:IPR018079|interpro:IPR002942(RNA-binding S4)|mint:O13516|interpro:IPR036986|ensemblgenomes:YPL081W(identity) ensemblfungi:YBR189W(gene)|rcsb pdb:6WOO|ensemblfungi:YBR189W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|reactome:R-SCE-156827|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0019843"(rRNA binding)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0045903"(positive regulation of translational fidelity)|reactome:R-SCE-1799339|reactome:R-SCE-6791226|reactome:R-SCE-72649|reactome:R-SCE-72689|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72706|reactome:R-SCE-975956|reactome:R-SCE-975957|sgd:S000000393|interpro:IPR022801|interpro:IPR005710(Ribosomal protein S4/S9, eukaryotic/archaeal)|interpro:IPR001912(Ribosomal protein S4)|interpro:IPR018079|interpro:IPR002942(RNA-binding S4)|refseq:NP_009748.3|mint:P05755|interpro:IPR036986|ensemblgenomes:YBR189W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:vAdW2QQWeep7eysGfwdrph+099Q559292 rogid:VVaUiekAztpO7wESU7DqtLDIb7E559292 rigid:T9aIfgy0eymGhEsM5lv+yF91TgU false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05031 uniprotkb:P36091 intact:EBI-27512|uniprotkb:D6W064|ensemblfungi:YMR238W intact:EBI-2052781|uniprotkb:D6VXP1|uniprotkb:Q66R60|ensemblfungi:YKL046C psi-mi:dfg5_yeast(display_long)|uniprotkb:DFG5(gene name)|psi-mi:DFG5(display_short)|uniprotkb:YMR238W(locus name)|uniprotkb:YM9959.20(orf name)|uniprotkb:Endo-alpha-1->6-D-mannanase DFG5(gene name synonym) psi-mi:dcw1_yeast(display_long)|uniprotkb:Endo-alpha-1->6-D-mannanase DCW1(gene name synonym)|uniprotkb:Defective cell wall 1(gene name synonym)|uniprotkb:YKL259(orf name)|uniprotkb:YKL046C(locus name)|uniprotkb:DCW1(gene name)|psi-mi:DCW1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318322|imex:IM-26944-501 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q05031|refseq:NP_013965.1|sgd:S000004851|dip:DIP-2739N|ensemblfungi:YMR238W(gene)|ensemblfungi:YMR238W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007117"(budding cell bud growth)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008496"(mannan endo-1,6-alpha-mannosidase activity)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0016052"(carbohydrate catabolic process)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0071555"(cell wall organization)|interpro:IPR005198(Glycoside hydrolase, family 76)|interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR014480(Mannan endo-1,6-alpha-mannosidase)|ensemblgenomes:YMR238W(identity) refseq:NP_012878.1|sgd:S000001529|interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR005198(Glycoside hydrolase, family 76)|interpro:IPR014480(Mannan endo-1,6-alpha-mannosidase)|mint:P36091|ensemblfungi:YKL046C(gene)|ensemblfungi:YKL046C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005933"(cellular bud)|go:"GO:0007117"(budding cell bud growth)|go:"GO:0008496"(mannan endo-1,6-alpha-mannosidase activity)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0016052"(carbohydrate catabolic process)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0071555"(cell wall organization)|ensemblgenomes:YKL046C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:nnHGptBCE3g8JbHRaiJvIbe4Nw8559292 rogid:cUTmFkcG9XK4BwQ2VebK5tm10Dw559292 rigid:vz9bV3kb+2w6aMtw7BGHMfLZOyw false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12450 uniprotkb:P39704 intact:EBI-6598|uniprotkb:D6W282|ensemblfungi:YOR016C intact:EBI-6587|uniprotkb:D6VPL1|ensemblfungi:YAL007C psi-mi:erp4_yeast(display_long)|uniprotkb:ERP4(gene name)|psi-mi:ERP4(display_short)|uniprotkb:YOR016C(locus name) psi-mi:erp2_yeast(display_long)|uniprotkb:ERP2(gene name)|psi-mi:ERP2(display_short)|uniprotkb:FUN54(orf name)|uniprotkb:YAL007C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318334|imex:IM-26944-607 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014659.1|sgd:S000005542|mint:Q12450|dip:DIP-7868N|ensemblfungi:YOR016C(gene)|ensemblfungi:YOR016C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|reactome:R-SCE-6811434|ensemblgenomes:YOR016C(identity) refseq:NP_009395.1|sgd:S000000005|mint:P39704|dip:DIP-5808N|ensemblfungi:YAL007C(gene)|ensemblfungi:YAL007C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|reactome:R-SCE-6811434|ensemblgenomes:YAL007C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:An7as6LjEDUYrLvEbua3xSL6bEk559292 rogid:qe1as0AJSSRC8SOKfxboQA2VKtY559292 rigid:tY4FxBS/0vLA1IzGM1DQtDL4MdQ false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48813 uniprotkb:P25376 intact:EBI-7758|uniprotkb:D6VTD0|ensemblfungi:YDR508C intact:EBI-2357|uniprotkb:D6VQZ1|ensemblfungi:YCL025C psi-mi:gnp1_yeast(display_long)|uniprotkb:GNP1(gene name)|psi-mi:GNP1(display_short)|uniprotkb:D9719.14(orf name)|uniprotkb:YDR508C(locus name) psi-mi:agp1_yeast(display_long)|uniprotkb:AGP1(gene name)|psi-mi:AGP1(display_short)|uniprotkb:YCL025C(locus name)|uniprotkb:YCL25C(orf name)|uniprotkb:Asparagine/glutamine permease(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318406|imex:IM-26944-523 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010796.1|sgd:S000002916|dip:DIP-1616N|ensemblfungi:YDR508C(gene)|ensemblfungi:YDR508C_mRNA(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015193"(L-proline transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:0098718"(serine import across plasma membrane)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region)|ensemblgenomes:YDR508C(identity) refseq:NP_009905.3|sgd:S000000530|dip:DIP-4973N|mint:P25376|ensemblfungi:YCL025C(gene)|ensemblfungi:YCL025C_mRNA(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015192"(L-phenylalanine transmembrane transporter activity)|go:"GO:0015193"(L-proline transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0098718"(serine import across plasma membrane)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region)|ensemblgenomes:YCL025C(identity) - crc64:9A5ED9CF7C1DD977 crc64:8E19A836C2F6C50F figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:ViyFFdYNUSkZx7fowfIivmwwM/k559292 rogid:bB5pBnaoMUTwxlz8v5MAjCWc4Mg559292 rigid:EYyMuL9YQiZtkLRy0tTIYOQL9wk false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12034 uniprotkb:P25567 intact:EBI-17335|uniprotkb:D6VTD6|uniprotkb:E9P8Z6|ensemblfungi:YDR515W intact:EBI-18084|uniprotkb:D6VQX8|ensemblfungi:YCL037C psi-mi:slf1_yeast(display_long)|uniprotkb:D9719.20(orf name)|uniprotkb:YDR515W(locus name)|uniprotkb:SLF1(gene name)|psi-mi:SLF1(display_short) psi-mi:sro9_yeast(display_long)|uniprotkb:SRO9(gene name)|psi-mi:SRO9(display_short)|uniprotkb:YCL037C(locus name)|uniprotkb:YCL37C(orf name)|uniprotkb:Suppressor of RHO3 protein 9(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318418|imex:IM-26944-525 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010803.3|sgd:S000002923|ensemblfungi:YDR515W(gene)|ensemblfungi:YDR515W_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006417"(regulation of translation)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0010494"(cytoplasmic stress granule)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390|dip:DIP-2938N|mint:Q12034|ensemblgenomes:YDR515W(identity) refseq:NP_009893.2|sgd:S000000542|ensemblfungi:YCL037C(gene)|ensemblfungi:YCL037C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005844"(polysome)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390|dip:DIP-6638N|mint:P25567|ensemblgenomes:YCL037C(identity) - - crc64:B1B720D40C7B9914 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:XBjQud6beJKzvJeWksARACuczoY559292 rogid:CouwiBsK7S3Tm6CoBsu3LdWfelg559292 rigid:3q/ohIcjcL4C6FzCotgwNfPnF4k false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03790 uniprotkb:Q05166 intact:EBI-27321|uniprotkb:D6VZX4|ensemblfungi:YMR153W intact:EBI-3035|uniprotkb:Q12456|uniprotkb:E9P903|uniprotkb:D6VRR0|ensemblfungi:YDL088C psi-mi:nup53_yeast(display_long)|uniprotkb:Nuclear pore protein NUP53(gene name synonym)|uniprotkb:NUP53(gene name)|psi-mi:NUP53(display_short)|uniprotkb:YMR153W(locus name)|uniprotkb:YM8520.02(orf name) psi-mi:nup59_yeast(display_long)|uniprotkb:ASM4(gene name)|psi-mi:ASM4(display_short)|uniprotkb:Nuclear pore protein NUP59(gene name synonym)|uniprotkb:NUP59(gene name synonym)|uniprotkb:D2420(orf name)|uniprotkb:YDL088C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318430|imex:IM-26944-341 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013873.1|sgd:S000004762|dip:DIP-1467N|ensemblfungi:YMR153W(gene)|ensemblfungi:YMR153W_mRNA(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|go:"GO:0060188"(regulation of protein desumoylation)|go:"GO:0072417"(response to spindle checkpoint signaling)|interpro:IPR007846(MPPN)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017389(Nucleoporin, NUP53)|interpro:IPR035979|rcsb pdb:3W3Y|rcsb pdb:5UAZ|ensemblgenomes:YMR153W(identity) refseq:NP_010195.1|sgd:S000002246|dip:DIP-1466N|mint:Q05166|ensemblfungi:YDL088C(gene)|ensemblfungi:YDL088C_mRNA(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007049"(cell cycle)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0051301"(cell division)|interpro:IPR007846(MPPN)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017389(Nucleoporin, NUP53)|interpro:IPR035979|ensemblgenomes:YDL088C(identity) - crc64:2ECE0C561D27E523 - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:csq2oRFswkgY2JkT+dmz/L7Zpfk559292 rogid:t8/JWDKB0Spe2P8qdZnKs/RB3SY559292 rigid:173SyJisU911RF7Xnxlhei7EsIg false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P01098 uniprotkb:P01097 intact:EBI-8080380|intact:MINT-2785764|uniprotkb:D6VRL9|ensemblfungi:YDL130W-A intact:EBI-8874|ensemblfungi:YDL181W|uniprotkb:D6VRH1 psi-mi:stf1_yeast(display_long)|uniprotkb:STF1(gene name)|psi-mi:STF1(display_short)|uniprotkb:AIS2(gene name synonym)|uniprotkb:ATP synthase F1 subunit epsilon(gene name synonym)|uniprotkb:YDL130BW(orf name)|uniprotkb:YDL130W-A(locus name) psi-mi:atif_yeast(display_long)|uniprotkb:INH1(gene name)|psi-mi:INH1(display_short)|uniprotkb:ATP synthase F1 subunit epsilon(gene name synonym)|uniprotkb:D1305(orf name)|uniprotkb:YDL181W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318442|imex:IM-26944-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010152.1|mint:P01098|interpro:IPR007648(Mitochondrial ATPase inhibitor, IATP)|sgd:S000007232|ensemblfungi:YDL130W-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051117"(ATPase binding)|ensemblfungi:YDL130W-A(gene)|ensemblgenomes:YDL130W-A(identity) ensemblfungi:YDL181W(gene)|ensemblfungi:YDL181W_mRNA(transcript)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0042030"(ATPase inhibitor activity)|interpro:IPR007648(Mitochondrial ATPase inhibitor, IATP)|rcsb pdb:3ZIA|refseq:NP_010100.1|sgd:S000002340|mint:P01097|dip:DIP-2985N|ensemblgenomes:YDL181W(identity) - comment:mint|function:This is 1 of 2 proteins that can stabilize the ATPase-inhibitor complex, which normally dissociates when externally added ATP has been consumed crc64:E1AF73A47F63CE58 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:YxrqEhb1G8Ln3oLqBYbVRmFM7E4559292 rogid:3wsu4TOLAZdm97Kfhla8l4UKFEk559292 rigid:LIGNnzVvA74xi0UM5JQwIougdM8 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11154 uniprotkb:P32327 intact:EBI-14358|uniprotkb:D6VU79|ensemblfungi:YGL062W intact:EBI-14365|uniprotkb:D6VQL4|ensemblfungi:YBR218C psi-mi:pyc1_yeast(display_long)|uniprotkb:PYV(gene name synonym)|uniprotkb:YGL062W(locus name)|uniprotkb:PYC1(gene name)|psi-mi:PYC1(display_short)|uniprotkb:Pyruvic carboxylase 1(gene name synonym) psi-mi:pyc2_yeast(display_long)|uniprotkb:PYC2(gene name)|psi-mi:PYC2(display_short)|uniprotkb:YBR218C(locus name)|uniprotkb:YBR1507(orf name)|uniprotkb:Pyruvic carboxylase 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318394|imex:IM-26944-521 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL062W(gene)|go:"GO:0004736"(pyruvate carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0009374"(biotin binding)|go:"GO:0046872"(metal ion binding)|ensemblfungi:YGL062W_mRNA(transcript)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR001882(Biotin-binding site)|interpro:IPR003379(Conserved carboxylase region)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR005930(Pyruvate carboxylase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016185(PreATP-grasp-like fold)|reactome:R-SCE-196780|reactome:R-SCE-70263|refseq:NP_011453.1|sgd:S000003030|mint:P11154|dip:DIP-6425N|ensemblgenomes:YGL062W(identity) refseq:NP_009777.1|sgd:S000000422|ensemblfungi:YBR218C(gene)|ensemblfungi:YBR218C_mRNA(transcript)|go:"GO:0004736"(pyruvate carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0009374"(biotin binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR001882(Biotin-binding site)|interpro:IPR003379(Conserved carboxylase region)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR005930(Pyruvate carboxylase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|mint:P32327|dip:DIP-6426N|ensemblgenomes:YBR218C(identity) - crc64:BC7110A8AFB23E04 crc64:AD60DA3A60F5E001 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:YleVCYfwUsqRJy5ua02EuklzpkQ559292 rogid:FvnnWuplwrt91+684m4fpfW2su8559292 rigid:oLwK7o8/13CAY3E++XQ5xwXJCxk false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32660 uniprotkb:Q12675 intact:EBI-3121|uniprotkb:D3DM74|ensemblfungi:YER166W intact:EBI-3114|uniprotkb:D6VS80|ensemblfungi:YDR093W psi-mi:atc5_yeast(display_long)|uniprotkb:DNF1(gene name)|psi-mi:DNF1(display_short)|uniprotkb:YER166W(locus name)|uniprotkb:SYGP-ORF7(orf name)|uniprotkb:Flippase DNF1(gene name synonym) psi-mi:atc4_yeast(display_long)|uniprotkb:DNF2(gene name)|psi-mi:DNF2(display_short)|uniprotkb:YDR093W(locus name)|uniprotkb:YD8557.01(orf name)|uniprotkb:Flippase DNF2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318490|imex:IM-26944-427 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000968|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR026871|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:7KY6|rcsb pdb:7KYB|rcsb pdb:7KYC|refseq:NP_011093.3|dip:DIP-7949N|mint:P32660|ensemblfungi:YER166W(gene)|ensemblfungi:YER166W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|ensemblgenomes:YER166W(identity) refseq:NP_010378.1|sgd:S000002500|dip:DIP-8055N|mint:Q12675|ensemblfungi:YDR093W(gene)|ensemblfungi:YDR093W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0015031"(protein transport)|go:"GO:0015247"(aminophospholipid flippase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140346"(phosphatidylserine flippase activity)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR026871|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:7KY5|rcsb pdb:7KY7|rcsb pdb:7KY8|rcsb pdb:7KY9|rcsb pdb:7KYA|ensemblgenomes:YDR093W(identity) - crc64:3CC3FBA8ADDE8960 - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:4ciEaV0aGjDqtpexkFJ0l737SpA559292 rogid:yfYH/L8WpAsxluGHGiYw3loRtRM559292 rigid:JHOki/TpxXmMpRQ/Eq8bAQpVpw4 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11076 uniprotkb:P19146 intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W intact:EBI-2820|uniprotkb:A2TBP3|uniprotkb:D6VRL1|ensemblfungi:YDL137W psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:arf2_yeast(display_long)|uniprotkb:ARF2(gene name)|psi-mi:ARF2(display_short)|uniprotkb:D2165(orf name)|uniprotkb:YDL137W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318454|imex:IM-26944-343 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438|ensemblgenomes:YDL192W(identity) refseq:NP_010144.1|sgd:S000002296|dip:DIP-2215N|mint:P19146|ensemblfungi:YDL137W(gene)|ensemblfungi:YDL137W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:1MR3|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438|ensemblgenomes:YDL137W(identity) - crc64:796859026AC63CC0 crc64:7E43FF792E8D64E8 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 rogid:I4V9cXleaZ2sAE2DXGKt8zpAPzw559292 rigid:AT1OwijMU0sHBxGzKEBnmNTCjC8 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34761 uniprotkb:Q07655 intact:EBI-20537|uniprotkb:D6W0Z0|ensemblfungi:YNL197C intact:EBI-31312|uniprotkb:D6VRD1|ensemblfungi:YDL224C psi-mi:whi3_yeast(display_long)|uniprotkb:WHI3(gene name)|psi-mi:WHI3(display_short)|uniprotkb:N1382(orf name)|uniprotkb:YNL197C(locus name) psi-mi:whi4_yeast(display_long)|uniprotkb:WHI4(gene name)|psi-mi:WHI4(display_short)|uniprotkb:D0839(orf name)|uniprotkb:YDL224C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318478|imex:IM-26944-95 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014202.1|sgd:S000005141|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|ensemblfungi:YNL197C(gene)|ensemblfungi:YNL197C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0032106"(positive regulation of response to extracellular stimulus)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0061013"(regulation of mRNA catabolic process)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071554"(cell wall organization or biogenesis)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:P34761|ensemblgenomes:YNL197C(identity) refseq:NP_010057.1|sgd:S000002383|dip:DIP-4321N|mint:Q07655|ensemblfungi:YDL224C(gene)|ensemblfungi:YDL224C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008361"(regulation of cell size)|go:"GO:0061157"(mRNA destabilization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|ensemblgenomes:YDL224C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:Xpn0uJiaylcupy9qYDLa0V++z6A559292 rogid:zPUzt32TQkMfrkafLvfsgHhZbYA559292 rigid:Mna4GPDmxgppt18JTgCWcZKWvYc false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04947 uniprotkb:Q12443 intact:EBI-38020|uniprotkb:D6VSL4|ensemblfungi:YDR233C intact:EBI-32591|uniprotkb:D6VRF0|ensemblfungi:YDL204W psi-mi:rtn1_yeast(display_long)|uniprotkb:RTN1(gene name)|psi-mi:RTN1(display_short)|uniprotkb:YDR233C(locus name) psi-mi:rtn2_yeast(display_long)|uniprotkb:RTN2(gene name)|psi-mi:RTN2(display_short)|uniprotkb:D1062(orf name)|uniprotkb:YDL204W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318466|imex:IM-26944-425 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002641|refseq:NP_010519.3|dip:DIP-4090N|mint:Q04947|ensemblfungi:YDR233C(gene)|ensemblfungi:YDR233C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032581"(ER-dependent peroxisome organization)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0071458"(integral component of cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0071788"(endoplasmic reticulum tubular network maintenance)|go:"GO:0071944"(cell periphery)|interpro:IPR003388(Reticulon)|ensemblgenomes:YDR233C(identity) refseq:NP_010077.1|sgd:S000002363|dip:DIP-4231N|mint:Q12443|ensemblfungi:YDL204W(gene)|ensemblfungi:YDL204W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032581"(ER-dependent peroxisome organization)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0071788"(endoplasmic reticulum tubular network maintenance)|go:"GO:0071944"(cell periphery)|interpro:IPR003388(Reticulon)|ensemblgenomes:YDL204W(identity) - crc64:245575E65D3C2193 crc64:E937E2B77759DFF5 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:EEXsl6gyB0GVuwAEwN1AAOF8h1E559292 rogid:jF49AeaM5t7a5TBw3/+tJ7H251g559292 rigid:Ln4rdPGXf97soYcHhQQU5ulx6Cg false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38695 uniprotkb:P32466 intact:EBI-8778|ensemblfungi:YHR096C|uniprotkb:D3DL46 intact:EBI-8770|ensemblfungi:YDR345C|uniprotkb:D6VSX5 psi-mi:hxt5_yeast(display_long)|uniprotkb:YHR096C(locus name)|uniprotkb:HXT5(gene name)|psi-mi:HXT5(display_short) psi-mi:hxt3_yeast(display_long)|uniprotkb:D9651.14(orf name)|uniprotkb:YDR345C(locus name)|uniprotkb:HXT3(gene name)|psi-mi:HXT3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318526|imex:IM-26944-97 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR096C(gene)|ensemblfungi:YHR096C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011964.1|sgd:S000001138|mint:P38695|dip:DIP-5594N|ensemblgenomes:YHR096C(identity) interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|interpro:IPR005828(General substrate transporter)|ensemblfungi:YDR345C(gene)|ensemblfungi:YDR345C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|refseq:NP_010632.1|sgd:S000002753|mint:P32466|dip:DIP-4178N|ensemblgenomes:YDR345C(identity) - crc64:6906721BAC1A5F87 - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:aZGrWmUu+AZ4G6qmTG+Z+p6i7hs559292 rogid:sklAjpmtbPADWjK3sLElxkiGw6k559292 rigid:pI5IgrKnGiyoZ9f0mHIuCvggfzE false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08412 uniprotkb:Q05610 intact:EBI-37580|uniprotkb:D6W2A8|ensemblfungi:YOR042W intact:EBI-31191|uniprotkb:Q66RE0|uniprotkb:D6VSQ5|ensemblfungi:YDR273W psi-mi:cue5_yeast(display_long)|uniprotkb:YOR042W(locus name)|uniprotkb:CUE5(gene name)|psi-mi:CUE5(display_short)|uniprotkb:Coupling of ubiquitin conjugation to ER degradation protein 5(gene name synonym) psi-mi:don1_yeast(display_long)|uniprotkb:DON1(gene name)|psi-mi:DON1(display_short)|uniprotkb:D9954.4(orf name)|uniprotkb:YDR273W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318514|imex:IM-26944-609 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014685.1|sgd:S000005568|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|mint:Q08412|interpro:IPR041807|ensemblfungi:YOR042W(gene)|ensemblfungi:YOR042W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0043130"(ubiquitin binding)|reactome:R-SCE-6798695|ensemblgenomes:YOR042W(identity) refseq:NP_010559.3|sgd:S000002681|dip:DIP-1577N|ensemblfungi:YDR273W(gene)|ensemblfungi:YDR273W_mRNA(transcript)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0051301"(cell division)|go:"GO:0070056"(prospore membrane leading edge)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR041807|ensemblgenomes:YDR273W(identity) - crc64:0D455F9AD637AC8D crc64:6E13542050862709 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:bUu2kNMFibdM8RUj460pMdBr2UA559292 rogid:lwba8lbFDuhj4kIx6JdrOVlRF0s559292 rigid:swkE5thr9agJeVmTwqHky8B4OzE false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29311 uniprotkb:P34730 intact:EBI-3661|uniprotkb:Q06854|uniprotkb:D3DM86|ensemblfungi:YER177W intact:EBI-3672|uniprotkb:A2TBP2|uniprotkb:Q06HN5|uniprotkb:D6VS86|ensemblfungi:YDR099W psi-mi:bmh1_yeast(display_long)|uniprotkb:YER177W(locus name)|uniprotkb:BMH1(gene name)|psi-mi:BMH1(display_short) psi-mi:bmh2_yeast(display_long)|uniprotkb:YD8557.08(orf name)|uniprotkb:YDR099W(locus name)|uniprotkb:BMH2(gene name)|psi-mi:BMH2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318502|imex:IM-26944-281 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000979|refseq:NP_011104.3|dip:DIP-4313N|mint:P29311|ensemblfungi:YER177W(gene)|ensemblfungi:YER177W_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030437"(ascospore formation)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0034221"(fungal-type cell wall chitin biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070842"(aggresome assembly)|go:"GO:0070873"(regulation of glycogen metabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:5N6N|rcsb pdb:6QK8|ensemblgenomes:YER177W(identity) sgd:S000002506|refseq:NP_010384.3|dip:DIP-1212N|mint:P34730|ensemblfungi:YDR099W(gene)|ensemblfungi:YDR099W_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0030437"(ascospore formation)|go:"GO:0034221"(fungal-type cell wall chitin biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0070873"(regulation of glycogen metabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|ensemblgenomes:YDR099W(identity) - crc64:0A234167E313688B crc64:74788A9103F129FB figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:RnX8tqsjlxM+7Mi+Thlhc1XrTy4559292 rogid:trVbn5NvV8o+49WbsQrvedJbAZI559292 rigid:cqqoPxCXDucOzgZgXn+VFzDqMu0 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38816 uniprotkb:P29509 intact:EBI-19502|uniprotkb:D3DL56|ensemblfungi:YHR106W intact:EBI-19497|uniprotkb:D6VSY3|ensemblfungi:YDR353W psi-mi:trxb2_yeast(display_long)|uniprotkb:YHR106W(locus name)|uniprotkb:TRR2(gene name)|psi-mi:TRR2(display_short) psi-mi:trxb1_yeast(display_long)|uniprotkb:D9476.5(orf name)|uniprotkb:YDR353W(locus name)|uniprotkb:TRR1(gene name)|psi-mi:TRR1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318538|imex:IM-26944-527 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011974.1|sgd:S000001148|ensemblfungi:YHR106W_mRNA(transcript)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0045454"(cell redox homeostasis)|interpro:IPR005982(Thioredoxin reductase)|interpro:IPR008255(Pyridine nucleotide-disulphide oxidoreductase, class-II, active site)|interpro:IPR023753|interpro:IPR036188|ensemblfungi:YHR106W(gene)|dip:DIP-1942N|mint:P38816|ensemblgenomes:YHR106W(identity) refseq:NP_010640.1|sgd:S000002761|ensemblfungi:YDR353W(gene)|ensemblfungi:YDR353W_mRNA(transcript)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0045454"(cell redox homeostasis)|interpro:IPR005982(Thioredoxin reductase)|interpro:IPR008255(Pyridine nucleotide-disulphide oxidoreductase, class-II, active site)|interpro:IPR023753|interpro:IPR036188|rcsb pdb:3D8X|rcsb pdb:3ITJ|dip:DIP-4319N|mint:P29509|ensemblgenomes:YDR353W(identity) - - crc64:9F9E58A4BAD859E1 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:MAzmQD74M9HfIswXAdQazKDYJvo559292 rogid:mDyO+A1dOgzMtGEDZ5D6nQfqHkw559292 rigid:dbmYS33+eeb9FG8nMXWiZDsgDk4 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12396 uniprotkb:P43555 intact:EBI-38641|uniprotkb:D6VY80|ensemblfungi:YLR080W intact:EBI-6439|uniprotkb:D6VTI2|ensemblfungi:YFL048C psi-mi:emp46_yeast(display_long)|uniprotkb:46 kDa endomembrane protein(gene name synonym)|uniprotkb:EMP46(gene name)|psi-mi:EMP46(display_short)|uniprotkb:YLR080W(locus name) psi-mi:emp47_yeast(display_long)|uniprotkb:YFL048C(locus name)|uniprotkb:EMP47(gene name)|psi-mi:EMP47(display_short)|uniprotkb:47 kDa endomembrane protein(gene name synonym)|uniprotkb:Endosomal P44 protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318622|imex:IM-26944-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013181.1|sgd:S000004070|dip:DIP-4209N|ensemblfungi:YLR080W(gene)|ensemblfungi:YLR080W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR016710(L-type lectin, fungi)|interpro:IPR035661|rcsb pdb:2A6V|rcsb pdb:2A6W|rcsb pdb:2A6X|ensemblgenomes:YLR080W(identity) refseq:NP_116606.1|sgd:S000001846|mint:P43555|dip:DIP-7675N|ensemblfungi:YFL048C(gene)|ensemblfungi:YFL048C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0097367"(carbohydrate derivative binding)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR016710(L-type lectin, fungi)|interpro:IPR035661|rcsb pdb:2A6Y|rcsb pdb:2A6Z|rcsb pdb:2A70|rcsb pdb:2A71|ensemblgenomes:YFL048C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:hCrYOuwXR3XzkMA6UecPqkakMn8559292 rogid:gq6bd7YuqqXJ+mHOhe1OZ0WU3K4559292 rigid:ted8vbJvUcUkHmQciYQZWS452uk false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40510 uniprotkb:P40054 intact:EBI-16821|ensemblfungi:YIL074C|uniprotkb:D6VVL0 intact:EBI-16961|uniprotkb:D3DLY8|ensemblfungi:YER081W psi-mi:ser33_yeast(display_long)|uniprotkb:SER33(gene name)|psi-mi:SER33(display_short)|uniprotkb:2-oxoglutarate reductase(gene name synonym)|uniprotkb:YIL074C(locus name) psi-mi:sera_yeast(display_long)|uniprotkb:SER3(gene name)|psi-mi:SER3(display_short)|uniprotkb:2-oxoglutarate reductase(gene name synonym)|uniprotkb:YER081W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318610|imex:IM-26944-431 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|refseq:NP_012191.1|sgd:S000001336|ensemblfungi:YIL074C(gene)|ensemblfungi:YIL074C_mRNA(transcript)|go:"GO:0004617"(phosphoglycerate dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0009070"(serine family amino acid biosynthetic process)|go:"GO:0016618"(hydroxypyruvate reductase activity)|go:"GO:0030267"("glyoxylate reductase (NADP+) activity")|go:"GO:0042802"(identical protein binding)|go:"GO:0051287"(NAD binding)|go:"GO:0061759"(alpha-ketoglutarate reductase activity)|interpro:IPR002912(Amino acid-binding ACT)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|dip:DIP-4483N|mint:P40510|ensemblgenomes:YIL074C(identity) refseq:NP_011004.3|sgd:S000000883|ensemblfungi:YER081W(gene)|ensemblfungi:YER081W_mRNA(transcript)|go:"GO:0004617"(phosphoglycerate dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0009070"(serine family amino acid biosynthetic process)|go:"GO:0016618"(hydroxypyruvate reductase activity)|go:"GO:0030267"("glyoxylate reductase (NADP+) activity")|go:"GO:0051287"(NAD binding)|go:"GO:0061759"(alpha-ketoglutarate reductase activity)|interpro:IPR002912(Amino acid-binding ACT)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|dip:DIP-5336N|mint:P40054|ensemblgenomes:YER081W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:EL+xZKwWXRcTkChe3CLKM+/WIzI559292 rogid:liGD7+FpTgCZYiHWbejPHNYk6As559292 rigid:mBKQPGn7agf1dJ0JQb/YOedJuig false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21373 uniprotkb:P32622 intact:EBI-20174|uniprotkb:Q54AD8|uniprotkb:D6VWM0|uniprotkb:E9P8Y8|ensemblfungi:YJR049C intact:EBI-22350|uniprotkb:D3DLK8|ensemblfungi:YEL041W psi-mi:utr1_yeast(display_long)|uniprotkb:UTR1(gene name)|psi-mi:UTR1(display_short)|uniprotkb:YJR049C(locus name)|uniprotkb:J1655(orf name)|uniprotkb:Unknown transcript 1 protein(gene name synonym) psi-mi:yef1_yeast(display_long)|uniprotkb:YEF1(gene name)|psi-mi:YEF1(display_short)|uniprotkb:SYGP-ORF17(orf name)|uniprotkb:YEL041W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318598|imex:IM-26944-187 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012583.1|sgd:S000003810|ensemblfungi:YJR049C(gene)|ensemblfungi:YJR049C_mRNA(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0042736"(NADH kinase activity)|interpro:IPR002504(ATP-NAD/AcoX kinase)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017437(ATP-NAD kinase, PpnK-type, all-beta)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|reactome:R-SCE-196807|mint:P21373|dip:DIP-4479N|ensemblgenomes:YJR049C(identity) refseq:NP_010873.1|sgd:S000000767|dip:DIP-1885N|mint:P32622|ensemblfungi:YEL041W(gene)|ensemblfungi:YEL041W_mRNA(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0042736"(NADH kinase activity)|interpro:IPR002504(ATP-NAD/AcoX kinase)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017437(ATP-NAD kinase, PpnK-type, all-beta)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|ensemblgenomes:YEL041W(identity) - crc64:1BF4F01D7213B94B crc64:E8301D466249DA27 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:l/mDQcBTaLoGMxT50H2W7npbw2g559292 rogid:HAL9emGKdVRCmdDG9CMzn68CGUI559292 rigid:40Q3rHri2jb0bgcJCtCNaU+vH8c false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10659 uniprotkb:P19358 intact:EBI-10789|ensemblfungi:YLR180W|uniprotkb:D6VYI4 intact:EBI-10795|uniprotkb:E9P927|ensemblfungi:YDR502C|uniprotkb:D6VTC4 psi-mi:metk1_yeast(display_long)|uniprotkb:SAM1(gene name)|psi-mi:SAM1(display_short)|uniprotkb:ETH10(gene name synonym)|uniprotkb:YLR180W(locus name)|uniprotkb:L9470.9(orf name)|uniprotkb:Methionine adenosyltransferase 1(gene name synonym) psi-mi:metk2_yeast(display_long)|uniprotkb:SAM2(gene name)|psi-mi:SAM2(display_short)|uniprotkb:ETH2(gene name synonym)|uniprotkb:YDR502C(locus name)|uniprotkb:D9719.8(orf name)|uniprotkb:Methionine adenosyltransferase 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318586|imex:IM-26944-429 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR180W(gene)|ensemblfungi:YLR180W_mRNA(transcript)|go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006555"(methionine metabolic process)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0046872"(metal ion binding)|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022628|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636|reactome:R-SCE-156581|reactome:R-SCE-1614635|reactome:R-SCE-2408508|refseq:NP_013281.1|sgd:S000004170|mint:P10659|dip:DIP-6667N|ensemblgenomes:YLR180W(identity) ensemblfungi:YDR502C(gene)|ensemblfungi:YDR502C_mRNA(transcript)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0046872"(metal ion binding)|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022628|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636|reactome:R-SCE-156581|reactome:R-SCE-1614635|reactome:R-SCE-2408508|go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006555"(methionine metabolic process)|sgd:S000002910|refseq:NP_010790.3|mint:P19358|dip:DIP-4001N|ensemblgenomes:YDR502C(identity) - crc64:18F82FC809EE4706 crc64:0AFCB0BA386F088B figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:PmIeDsMIksGSxihwmK1DqLFOItc559292 rogid:fLg9TMOk+nR4ZuRNqkqur0qzv/E559292 rigid:yn3DNVCSSXgU0gO6Y/BV7nnUvuY false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P26570 uniprotkb:P33329 intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 intact:EBI-13815|ensemblfungi:YDR436W|uniprotkb:D6VT63 psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:ppz2_yeast(display_long)|uniprotkb:PPZ2(gene name)|psi-mi:PPZ2(display_short)|uniprotkb:D9461.22(orf name)|uniprotkb:YDR436W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318562|imex:IM-26944-345 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N|ensemblgenomes:YML016C(identity) ensemblfungi:YDR436W(gene)|ensemblfungi:YDR436W_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0046872"(metal ion binding)|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|go:"GO:0106306"|refseq:NP_010724.1|sgd:S000002844|mint:P33329|dip:DIP-6355N|ensemblgenomes:YDR436W(identity) - crc64:8B7F009521F72C15 crc64:3095F37046489AFB figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 rogid:WpYxSWimbMNz9ZdZHpezPp/B2Sc559292 rigid:/ZVn70UXbyyBm8DdVD/tUqmpM7U false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32324 uniprotkb:P32324 intact:EBI-6333|uniprotkb:Q6JEF7|uniprotkb:D6VT19|ensemblfungi:YDR385W|ensemblfungi:YOR133W intact:EBI-6333|uniprotkb:Q6JEF7|uniprotkb:D6VT19|ensemblfungi:YDR385W|ensemblfungi:YOR133W psi-mi:ef2_yeast(display_long)|uniprotkb:EFT1(gene name)|psi-mi:EFT1(display_short)|uniprotkb:YOR133W(locus name)|uniprotkb:O3317(orf name)|uniprotkb:YOR3317W(orf name)|uniprotkb:EFT2(gene name)|psi-mi:EFT2(display_short)|uniprotkb:YDR385W(locus name)|uniprotkb:Translation elongation factor 2(gene name synonym)|uniprotkb:Eukaryotic elongation factor 2(gene name synonym)|uniprotkb:Ribosomal translocase(gene name synonym) psi-mi:ef2_yeast(display_long)|uniprotkb:EFT1(gene name)|psi-mi:EFT1(display_short)|uniprotkb:YOR133W(locus name)|uniprotkb:O3317(orf name)|uniprotkb:YOR3317W(orf name)|uniprotkb:EFT2(gene name)|psi-mi:EFT2(display_short)|uniprotkb:YDR385W(locus name)|uniprotkb:Translation elongation factor 2(gene name synonym)|uniprotkb:Eukaryotic elongation factor 2(gene name synonym)|uniprotkb:Ribosomal translocase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318550|imex:IM-26944-611 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010673.1|refseq:NP_014776.1|sgd:S000005659|sgd:S000002793|ensemblfungi:YDR385W(gene)|ensemblfungi:YDR385W_mRNA(transcript)|ensemblfungi:YOR133W(gene)|ensemblfungi:YOR133W_mRNA(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0019843"(rRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0051087"(chaperone binding)|go:"GO:1990145"(maintenance of translational fidelity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|mint:P32324|dip:DIP-4911N|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|rcsb pdb:1N0U|rcsb pdb:1N0V|rcsb pdb:1U2R|rcsb pdb:1ZM2|rcsb pdb:1ZM3|rcsb pdb:1ZM4|rcsb pdb:1ZM9|rcsb pdb:2E1R|rcsb pdb:2NPF|rcsb pdb:2P8W|rcsb pdb:2P8X|rcsb pdb:2P8Y|rcsb pdb:2P8Z|rcsb pdb:2ZIT|rcsb pdb:3B78|rcsb pdb:3B82|rcsb pdb:3B8H|rcsb pdb:3DNY|rcsb pdb:4V4B|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|reactome:R-SCE-156902|reactome:R-SCE-5358493|reactome:R-SCE-6798695|ensemblgenomes:YOR133W(identity) refseq:NP_010673.1|refseq:NP_014776.1|sgd:S000005659|sgd:S000002793|ensemblfungi:YDR385W(gene)|ensemblfungi:YDR385W_mRNA(transcript)|ensemblfungi:YOR133W(gene)|ensemblfungi:YOR133W_mRNA(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0019843"(rRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0051087"(chaperone binding)|go:"GO:1990145"(maintenance of translational fidelity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|mint:P32324|dip:DIP-4911N|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|rcsb pdb:1N0U|rcsb pdb:1N0V|rcsb pdb:1U2R|rcsb pdb:1ZM2|rcsb pdb:1ZM3|rcsb pdb:1ZM4|rcsb pdb:1ZM9|rcsb pdb:2E1R|rcsb pdb:2NPF|rcsb pdb:2P8W|rcsb pdb:2P8X|rcsb pdb:2P8Y|rcsb pdb:2P8Z|rcsb pdb:2ZIT|rcsb pdb:3B78|rcsb pdb:3B82|rcsb pdb:3B8H|rcsb pdb:3DNY|rcsb pdb:4V4B|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|reactome:R-SCE-156902|reactome:R-SCE-5358493|reactome:R-SCE-6798695|ensemblgenomes:YDR385W(identity) - crc64:FD2F8073CB9B66AA crc64:FD2F8073CB9B66AA figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:mlyt9YKZrGhGbsSlvxNJ0p1C67I559292 rogid:mlyt9YKZrGhGbsSlvxNJ0p1C67I559292 rigid:jWPbFhrzSUX8llcuPU1CyVbbIq4 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12236 uniprotkb:Q03407 intact:EBI-9844|intact:EBI-2935811|uniprotkb:D6W1W8|ensemblfungi:YOL100W intact:EBI-32467|uniprotkb:D6VTB3|ensemblfungi:YDR490C psi-mi:pkh2_yeast(display_long)|uniprotkb:YOL100W(locus name)|uniprotkb:HRC1081(orf name)|uniprotkb:PKH2(gene name)|psi-mi:PKH2(display_short)|uniprotkb:PKB-activating kinase homolog 2(gene name synonym) psi-mi:pkh1_yeast(display_long)|uniprotkb:3-phosphoinositide-dependent protein kinase 1(gene name synonym)|uniprotkb:PKH1(gene name)|psi-mi:PKH1(display_short)|uniprotkb:YDR490C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318574|imex:IM-26944-347 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014541.1|sgd:S000005460|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0060211"("regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|ensemblfungi:YOL100W(gene)|ensemblfungi:YOL100W_mRNA(transcript)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039046|reactome:R-SCE-114604|reactome:R-SCE-1257604|reactome:R-SCE-165158|reactome:R-SCE-202424|reactome:R-SCE-2730905|reactome:R-SCE-389357|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0004672"(protein kinase activity)|reactome:R-SCE-392451|reactome:R-SCE-5218920|reactome:R-SCE-5218921|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-6804757|reactome:R-SCE-9634635|reactome:R-SCE-5625740|dip:DIP-6295N|mint:Q12236|ensemblgenomes:YOL100W(identity) sgd:S000002898|refseq:NP_010778.3|dip:DIP-1518N|mint:Q03407|ensemblfungi:YDR490C(gene)|ensemblfungi:YDR490C_mRNA(transcript)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0060211"("regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039046|ensemblgenomes:YDR490C(identity) - crc64:BE0DD9D49AC2EBC3 crc64:7FFD32E8BE8BC367 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:KzJ+WGY+PylRDsK1olfak8IyuXM559292 rogid:hpsrmcmAD7P9gkV3cPpXuTNgTMc559292 rigid:xMvj3RRoGcUpOuRbl0GxoOtkkPo false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32793 uniprotkb:P43603 intact:EBI-24460|uniprotkb:D3DKW1|ensemblfungi:YHR016C intact:EBI-22980|uniprotkb:D6VTQ4|ensemblfungi:YFR024C-A psi-mi:ysc84_yeast(display_long)|uniprotkb:YSC84(gene name)|psi-mi:YSC84(display_short)|uniprotkb:LSB4(gene name synonym)|uniprotkb:LAS seventeen-binding protein 4(gene name synonym)|uniprotkb:YHR016C(locus name) psi-mi:lsb3_yeast(display_long)|uniprotkb:LSB3(gene name)|psi-mi:LSB3(display_short)|uniprotkb:YFR024C(orf name)|uniprotkb:YFR024C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318646|imex:IM-26944-349 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011880.1|sgd:S000001058|dip:DIP-2026N|mint:P32793|ensemblfungi:YHR016C(gene)|ensemblfungi:YHR016C_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization)|interpro:IPR001452(Src homology-3)|interpro:IPR007461(Protein of unknown function DUF500)|interpro:IPR033643|interpro:IPR036028|rcsb pdb:2A08|ensemblgenomes:YHR016C(identity) sgd:S000002968|refseq:NP_219497.4|dip:DIP-6259N|mint:P43603|ensemblfungi:YFR024C-A(gene)|ensemblfungi:YFR024C-A_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005935"(cellular bud neck)|go:"GO:0030479"(actin cortical patch)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization)|interpro:IPR001452(Src homology-3)|interpro:IPR007461(Protein of unknown function DUF500)|interpro:IPR033643|interpro:IPR036028|rcsb pdb:1OOT|rcsb pdb:1SSH|ensemblgenomes:YFR024C-A(identity) - crc64:DE42E8ECF5B83C92 crc64:F486C787B5771AAC figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:hirm/OlqdPxvJNPbha68BSFIvmQ559292 rogid:zKMZQRpG4d/at/NecQDyEi/kVKg559292 rigid:R8pjxQemMdqoLMS4NXpZfJUH2mE false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P04807 uniprotkb:P04806 intact:EBI-8738|ensemblfungi:YGL253W|uniprotkb:Q05838|uniprotkb:D6VV82 intact:EBI-8732|ensemblfungi:YFR053C|uniprotkb:D6VTT6 psi-mi:hxkb_yeast(display_long)|uniprotkb:HKB(gene name synonym)|uniprotkb:NRB486(orf name)|uniprotkb:YGL253W(locus name)|uniprotkb:HXK2(gene name)|psi-mi:HXK2(display_short)|uniprotkb:HEX1(gene name synonym)|uniprotkb:Hexokinase-B(gene name synonym)|uniprotkb:Hexokinase PII(gene name synonym) psi-mi:hxka_yeast(display_long)|uniprotkb:HKA(gene name synonym)|uniprotkb:YFR053C(locus name)|uniprotkb:HXK1(gene name)|psi-mi:HXK1(display_short)|uniprotkb:Hexokinase-A(gene name synonym)|uniprotkb:Hexokinase PI(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318658|imex:IM-26944-613 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL253W(gene)|ensemblfungi:YGL253W_mRNA(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0004340"(glucokinase activity)|go:"GO:0004396"(hexokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005536"(glucose binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006013"(mannose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008361"(regulation of cell size)|go:"GO:0008865"(fructokinase activity)|go:"GO:0019158"(mannokinase activity)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032445"(fructose import)|go:"GO:0046015"(regulation of transcription by glucose)|go:"GO:0046323"(glucose import)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001312(Hexokinase)|interpro:IPR019807|interpro:IPR022672|interpro:IPR022673|interpro:IPR043129|rcsb pdb:1IG8|rcsb pdb:2YHX|rcsb pdb:5UWT|reactome:R-SCE-170822|reactome:R-SCE-6798695|reactome:R-SCE-70171|refseq:NP_011261.1|sgd:S000003222|mint:P04807|dip:DIP-2380N|ensemblgenomes:YGL253W(identity) ensemblfungi:YFR053C(gene)|ensemblfungi:YFR053C_mRNA(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0004340"(glucokinase activity)|go:"GO:0004396"(hexokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005536"(glucose binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006013"(mannose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008865"(fructokinase activity)|go:"GO:0019158"(mannokinase activity)|go:"GO:0032445"(fructose import)|go:"GO:0046323"(glucose import)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|interpro:IPR001312(Hexokinase)|interpro:IPR019807|interpro:IPR022672|interpro:IPR022673|interpro:IPR043129|rcsb pdb:1HKG|rcsb pdb:3B8A|reactome:R-SCE-170822|reactome:R-SCE-6798695|reactome:R-SCE-70171|refseq:NP_116711.3|sgd:S000001949|mint:P04806|dip:DIP-5377N|ensemblgenomes:YFR053C(identity) - crc64:D55FF3F8992B2FEF crc64:AF5C9DA8F17BC3D0 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:DGycg0nxbxnH7W3sJoM9k4t3qYc559292 rogid:zsmpb9CuEStI8OqnH/VF1X/c40A559292 rigid:JPGZ9XjXD5FMzrWyhWWlQNuWnro false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06169 uniprotkb:P53203 intact:EBI-31008|intact:EBI-937900|uniprotkb:Q66R43|uniprotkb:D6VYW6|ensemblfungi:YLR324W intact:EBI-23069|uniprotkb:D6VUE1|ensemblfungi:YGR004W psi-mi:pex30_yeast(display_long)|uniprotkb:PEX30(gene name)|psi-mi:PEX30(display_short)|uniprotkb:Peroxin-30(gene name synonym)|uniprotkb:YLR324W(locus name) psi-mi:pex31_yeast(display_long)|uniprotkb:Peroxin-31(gene name synonym)|uniprotkb:PEX31(gene name)|psi-mi:PEX31(display_short)|uniprotkb:YGR004W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318670|imex:IM-26944-99 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013428.1|sgd:S000004316|dip:DIP-1800N|mint:Q06169|ensemblfungi:YLR324W(gene)|ensemblfungi:YLR324W_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005933"(cellular bud)|go:"GO:0007031"(peroxisome organization)|go:"GO:0032581"(ER-dependent peroxisome organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071944"(cell periphery)|go:"GO:0097749"(membrane tubulation)|go:"GO:1900063"(regulation of peroxisome organization)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR010482(Integral peroxisomal membrane peroxin)|ensemblgenomes:YLR324W(identity) refseq:NP_011518.1|sgd:S000003236|dip:DIP-5455N|ensemblfungi:YGR004W(gene)|ensemblfungi:YGR004W_mRNA(transcript)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007031"(peroxisome organization)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071944"(cell periphery)|go:"GO:0097749"(membrane tubulation)|go:"GO:1900063"(regulation of peroxisome organization)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR010482(Integral peroxisomal membrane peroxin)|ensemblgenomes:YGR004W(identity) - crc64:417DBE56B1C8B1D5 - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:vkvJ4GqSW60wMG0m3ChlSzwcC3c559292 rogid:A8m6e08wcV/TdPj9ks1r34U8G80559292 rigid:EiYd1PA6jGzHbdk58lvSJeSO6Zk false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06178 uniprotkb:P53204 intact:EBI-11803|ensemblfungi:YLR328W|uniprotkb:D6VYX0 intact:EBI-23073|uniprotkb:D6VUE7|ensemblfungi:YGR010W psi-mi:nma1_yeast(display_long)|uniprotkb:NMA1(gene name)|psi-mi:NMA1(display_short)|uniprotkb:"NAD(+) pyrophosphorylase 1"(gene name synonym)|uniprotkb:"NAD(+) diphosphorylase 1"(gene name synonym)|uniprotkb:Nicotinamide-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:Nicotinate-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:L8543.16(orf name)|uniprotkb:YLR328W(locus name) psi-mi:nma2_yeast(display_long)|uniprotkb:NMA2(gene name)|psi-mi:NMA2(display_short)|uniprotkb:"NAD(+) pyrophosphorylase 2"(gene name synonym)|uniprotkb:"NAD(+) diphosphorylase 2"(gene name synonym)|uniprotkb:Nicotinamide-nucleotide adenylyltransferase 2(gene name synonym)|uniprotkb:Nicotinate-nucleotide adenylyltransferase 2(gene name synonym)|uniprotkb:YGR010W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318682|imex:IM-26944-351 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR328W(gene)|ensemblfungi:YLR328W_mRNA(transcript)|go:"GO:0000309"(nicotinamide-nucleotide adenylyltransferase activity)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|reactome:R-SCE-196807|refseq:NP_013432.1|sgd:S000004320|dip:DIP-1228N|mint:Q06178|ensemblgenomes:YLR328W(identity) refseq:NP_011524.1|sgd:S000003242|dip:DIP-1227N|mint:P53204|ensemblfungi:YGR010W(gene)|ensemblfungi:YGR010W_mRNA(transcript)|go:"GO:0000309"(nicotinamide-nucleotide adenylyltransferase activity)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0009435"(NAD biosynthetic process)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|reactome:R-SCE-196807|ensemblgenomes:YGR010W(identity) - crc64:A176964E56A30DD8 - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:VzrKsykGbQsR8Eh7CHCwn/bCID8559292 rogid:AdSZgVYoChR4aYSPC7gsAQ5Pws0559292 rigid:kWSUw3O+zKVlUCxmrFscRQB1Qpk false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27472 uniprotkb:P23337 intact:EBI-8036|uniprotkb:D6VYQ5|ensemblfungi:YLR258W intact:EBI-8031|uniprotkb:D6VTP6|ensemblfungi:YFR015C psi-mi:gys2_yeast(display_long)|uniprotkb:L8479.8(orf name)|uniprotkb:YLR258W(locus name)|uniprotkb:GSY2(gene name)|psi-mi:GSY2(display_short) psi-mi:gys1_yeast(display_long)|uniprotkb:YFR015C(locus name)|uniprotkb:GSY1(gene name)|psi-mi:GSY1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318634|imex:IM-26944-283 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013359.1|sgd:S000004248|mint:P27472|dip:DIP-1255N|ensemblfungi:YLR258W(gene)|ensemblfungi:YLR258W_mRNA(transcript)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR008631(Glycogen synthase)|rcsb pdb:3NAZ|rcsb pdb:3NB0|rcsb pdb:3NCH|rcsb pdb:3O3C|rcsb pdb:3RSZ|rcsb pdb:3RT1|rcsb pdb:4KQ2|rcsb pdb:4KQM|rcsb pdb:5SUK|rcsb pdb:5SUL|rcsb pdb:5UW0|rcsb pdb:5UW1|rcsb pdb:5UW4|rcsb pdb:5UX7|rcsb pdb:5VNC|rcsb pdb:6U77|reactome:R-SCE-3322077|ensemblgenomes:YLR258W(identity) refseq:NP_116670.1|sgd:S000001911|mint:P23337|dip:DIP-5354N|ensemblfungi:YFR015C(gene)|ensemblfungi:YFR015C_mRNA(transcript)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005978"(glycogen biosynthetic process)|interpro:IPR008631(Glycogen synthase)|reactome:R-SCE-3322077|ensemblgenomes:YFR015C(identity) - crc64:4670D8328CEDB0D2 crc64:9EF2D3858529E68A figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:K8l8dzJOtoIWZHpDN8Bq31o6ahA559292 rogid:YDyqS1ELi4nkwAfLsPv+FNzh87k559292 rigid:WF0tBT7W556EEiv449ZQg/LMtTI false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53390 uniprotkb:P40260 intact:EBI-10729|uniprotkb:Q6B2F5|ensemblfungi:YPR138C|uniprotkb:D6W4D6 intact:EBI-10714|ensemblfungi:YGR121C|uniprotkb:D6VUQ2 psi-mi:mep3_yeast(display_long)|uniprotkb:MEP3(gene name)|psi-mi:MEP3(display_short)|uniprotkb:YPR138C(locus name)|uniprotkb:P9659.14(orf name)|uniprotkb:AMT3(gene name synonym) psi-mi:mep1_yeast(display_long)|uniprotkb:MEP1(gene name)|psi-mi:MEP1(display_short)|uniprotkb:YGR121C(locus name)|uniprotkb:G6331(orf name)|uniprotkb:AMT1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318709|imex:IM-26944-189 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015464.1|sgd:S000006342|ensemblfungi:YPR138C(gene)|ensemblfungi:YPR138C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|mint:P53390|dip:DIP-4909N|ensemblgenomes:YPR138C(identity) ensemblfungi:YGR121C(gene)|ensemblfungi:YGR121C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|sgd:S000003353|refseq:NP_011636.3|mint:P40260|dip:DIP-5530N|ensemblgenomes:YGR121C(identity) - crc64:2309338F36D96258 - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:UajvXf1E8FU957+oquLoPeSfTjk559292 rogid:VnoBl5jhQD24N0SbCLv68HCwl1U559292 rigid:O/pzYx4h6t3Hrvh/1WrZd98IUwA false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06449 uniprotkb:P53281 intact:EBI-35523|uniprotkb:D6W4F0|ensemblfungi:YPR154W intact:EBI-23329|uniprotkb:D6VUR8|ensemblfungi:YGR136W psi-mi:pin3_yeast(display_long)|uniprotkb:PIN3(gene name)|psi-mi:PIN3(display_short)|uniprotkb:LAS seventeen-binding protein 2(gene name synonym)|uniprotkb:LSB2(gene name synonym)|uniprotkb:YPR154W(locus name) psi-mi:lsb1_yeast(display_long)|uniprotkb:LSB1(gene name)|psi-mi:LSB1(display_short)|uniprotkb:YGR136W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318721|imex:IM-26944-617 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015480.1|sgd:S000006358|dip:DIP-6257N|ensemblfungi:YPR154W(gene)|ensemblfungi:YPR154W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|rcsb pdb:1YNZ|rcsb pdb:1ZX6|go:"GO:0030479"(actin cortical patch)|ensemblgenomes:YPR154W(identity) refseq:NP_011652.1|sgd:S000003368|dip:DIP-1863N|mint:P53281|ensemblfungi:YGR136W(gene)|ensemblfungi:YGR136W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030479"(actin cortical patch)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|ensemblgenomes:YGR136W(identity) - - crc64:5F0B1361AF84AA79 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:JeNsn3H/VROp194KQLL/o9IhY6Q559292 rogid:R1HwHYkR6yeO64d9A2xUBxvijvU559292 rigid:3ByB/AKfcFKzBUOjJPJ9pdyv0ZQ false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06451 uniprotkb:P53283 intact:EBI-34275|uniprotkb:D6W4F2|ensemblfungi:YPR156C intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C psi-mi:tpo3_yeast(display_long)|uniprotkb:TPO3(gene name)|psi-mi:TPO3(display_short)|uniprotkb:P9584.7(orf name)|uniprotkb:YPR156C(locus name) psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318733|imex:IM-26944-621 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015482.1|sgd:S000006360|mint:Q06451|dip:DIP-3907N|ensemblfungi:YPR156C(gene)|ensemblfungi:YPR156C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259|ensemblgenomes:YPR156C(identity) refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259|ensemblgenomes:YGR138C(identity) - crc64:D260ED161F800502 - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:oVpx7Bjk/mK2Q7+/j05tX3gHw7k559292 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 rigid:vxufMYEfF3yv/hxJ0HlG7+0KsJw false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06144 uniprotkb:P53224 intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W intact:EBI-12592|uniprotkb:D6VUH5|ensemblfungi:YGR038W psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:orm1_yeast(display_long)|uniprotkb:YGR038W(locus name)|uniprotkb:ORM1(gene name)|psi-mi:ORM1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318697|imex:IM-26944-615 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695|ensemblgenomes:YLR350W(identity) ensemblfungi:YGR038W(gene)|ensemblfungi:YGR038W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|refseq:NP_011552.1|sgd:S000003270|reactome:R-SCE-6798695|dip:DIP-8124N|ensemblgenomes:YGR038W(identity) - crc64:2F474503CAB7C195 crc64:4387D00ACE4F3A1D figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 rogid:HsbGN/V/sSXpez8xOIDmVo6oiSk559292 rigid:ZzX1dvxCkbh0tATcrDK+deJMMrU false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23292 uniprotkb:P23291 intact:EBI-4729|uniprotkb:D6W129|ensemblfungi:YNL154C intact:EBI-4718|uniprotkb:E9P958|uniprotkb:D3DL84|ensemblfungi:YHR135C psi-mi:kc12_yeast(display_long)|uniprotkb:YCK2(gene name)|psi-mi:YCK2(display_short)|uniprotkb:CKI1(gene name synonym)|uniprotkb:YNL154C(locus name)|uniprotkb:N1755(orf name) psi-mi:kc11_yeast(display_long)|uniprotkb:YCK1(gene name)|psi-mi:YCK1(display_short)|uniprotkb:CKI2(gene name synonym)|uniprotkb:YHR135C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318793|imex:IM-26944-363 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014245.1|sgd:S000005098|ensemblfungi:YNL154C(gene)|ensemblfungi:YNL154C_mRNA(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|dip:DIP-720N|mint:P23292|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005937"(mating projection)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0009749"(response to glucose)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|ensemblgenomes:YNL154C(identity) refseq:NP_012003.1|sgd:S000001177|dip:DIP-719N|mint:P23291|ensemblfungi:YHR135C(gene)|ensemblfungi:YHR135C_mRNA(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0009749"(response to glucose)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:5X18|ensemblgenomes:YHR135C(identity) - crc64:A88D99BC265BF4FA crc64:77344717818C2D17 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:1nUIikls1l+co991K+hA3Njzmuc559292 rogid:pFpwRNbvvNZ1NPc7VMVXSivwMeI559292 rigid:38nNhU2IJ8BwFisxQrh/6sfGtUk false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P22217 uniprotkb:P22803 intact:EBI-19607|uniprotkb:D6VY45|ensemblfungi:YLR043C intact:EBI-19598|uniprotkb:D6VUZ2|ensemblfungi:YGR209C psi-mi:trx1_yeast(display_long)|uniprotkb:TRX1(gene name)|psi-mi:TRX1(display_short)|uniprotkb:TRX2(gene name synonym)|uniprotkb:YLR043C(locus name)|uniprotkb:Thioredoxin I(gene name synonym)|uniprotkb:Thioredoxin-2(gene name synonym) psi-mi:trx2_yeast(display_long)|uniprotkb:TRX2(gene name)|psi-mi:TRX2(display_short)|uniprotkb:TRX1(gene name synonym)|uniprotkb:G7746(orf name)|uniprotkb:YGR209C(locus name)|uniprotkb:Thioredoxin II(gene name synonym)|uniprotkb:Thioredoxin-1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318745|imex:IM-26944-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013144.1|sgd:S000004033|interpro:IPR005746(Thioredoxin)|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|ensemblfungi:YLR043C(gene)|ensemblfungi:YLR043C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0015031"(protein transport)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0080058"(protein deglutathionylation)|rcsb pdb:2I9H|rcsb pdb:2N5A|rcsb pdb:2N5B|rcsb pdb:3F3Q|rcsb pdb:3F3R|go:"GO:0006662"(glycerol ether metabolic process)|mint:P22217|interpro:IPR036249|ensemblgenomes:YLR043C(identity) sgd:S000003441|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0015031"(protein transport)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0080058"(protein deglutathionylation)|interpro:IPR005746(Thioredoxin)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|rcsb pdb:2FA4|rcsb pdb:2HSY|rcsb pdb:3PIN|rcsb pdb:4DSS|rcsb pdb:7BVV|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|ensemblfungi:YGR209C(gene)|ensemblfungi:YGR209C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000103"(sulfate assimilation)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006662"(glycerol ether metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|refseq:NP_011725.3|dip:DIP-5552N|mint:P22803|ensemblgenomes:YGR209C(identity) - - crc64:071503762C90D451 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:HTTjl3NGIuQllhjAI5NASyqqIlc559292 rogid:pRt9fGROPXW+o4g6ynOmCDiclFk559292 rigid:wIlIWFYYid3t71hgPsUZjoLgyn4 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38853 uniprotkb:P50090 intact:EBI-9619|ensemblfungi:YHR158C|uniprotkb:D3DLA7|uniprotkb:E9P8X4 intact:EBI-9630|ensemblfungi:YGR238C|uniprotkb:D6VV18 psi-mi:kel1_yeast(display_long)|uniprotkb:KEL1(gene name)|psi-mi:KEL1(display_short)|uniprotkb:YHR158C(locus name) psi-mi:kel2_yeast(display_long)|uniprotkb:KEL2(gene name)|psi-mi:KEL2(display_short)|uniprotkb:G8585(orf name)|uniprotkb:YGR238C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318757|imex:IM-26944-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR158C(gene)|ensemblfungi:YHR158C_mRNA(transcript)|go:"GO:0000755"(cytogamy)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0090337"(regulation of formin-nucleated actin cable assembly)|go:"GO:1990615"(Kelch-containing formin regulatory complex)|interpro:IPR015915(Kelch-type beta propeller)|refseq:NP_012028.1|sgd:S000001201|dip:DIP-1403N|mint:P38853|ensemblgenomes:YHR158C(identity) go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0090337"(regulation of formin-nucleated actin cable assembly)|go:"GO:1990615"(Kelch-containing formin regulatory complex)|interpro:IPR015915(Kelch-type beta propeller)|ensemblfungi:YGR238C(gene)|ensemblfungi:YGR238C_mRNA(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0008360"(regulation of cell shape)|refseq:NP_011754.3|sgd:S000003470|dip:DIP-4229N|mint:P50090|ensemblgenomes:YGR238C(identity) - crc64:43D0FC570F1D5E4D crc64:63B9772FF017E6D9 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:pdHtsxpdf1r7G2K9e9EPHajJS3w559292 rogid:lSnioafH7gyCBHbl539AXlWBAxE559292 rigid:j3fxfssltKjMoDuiB8X1j+KatoQ false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02201 uniprotkb:P38755 intact:EBI-12636|uniprotkb:D6VXT9|ensemblfungi:YKR003W intact:EBI-12641|uniprotkb:D3DKR7|ensemblfungi:YHR001W psi-mi:osh6_yeast(display_long)|uniprotkb:YK102(orf name)|uniprotkb:YKR003W(locus name)|uniprotkb:OSH6(gene name)|psi-mi:OSH6(display_short) psi-mi:osh7_yeast(display_long)|uniprotkb:YHR001W(locus name)|uniprotkb:OSH7(gene name)|psi-mi:OSH7(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318769|imex:IM-26944-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0015914"(phospholipid transport)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0120015"(sterol transfer activity)|rcsb pdb:4B2Z|rcsb pdb:4PH7|reactome:R-SCE-1482801|reactome:R-SCE-192105|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|ensemblfungi:YKR003W(gene)|ensemblfungi:YKR003W_mRNA(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|refseq:NP_012928.1|sgd:S000001711|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|mint:Q02201|ensemblgenomes:YKR003W(identity) ensemblfungi:YHR001W(gene)|ensemblfungi:YHR001W_mRNA(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0015914"(phospholipid transport)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|reactome:R-SCE-1482801|reactome:R-SCE-192105|refseq:NP_011863.1|sgd:S000001043|mint:P38755|dip:DIP-6363N|ensemblgenomes:YHR001W(identity) - - crc64:1C972ED6517D529B figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:aOZdSdLn96ns0C9w9E3r62iNyYo559292 rogid:CnsyJOWY7SpdJZ6GeUshxYiBNJk559292 rigid:wCMg5liTIRV0d/oNIgl7oivu7KM false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17898 uniprotkb:P22140 intact:EBI-2050738|uniprotkb:D6W152|ensemblfungi:YNL130C intact:EBI-6494|uniprotkb:D3DL73|ensemblfungi:YHR123W psi-mi:cpt1_yeast(display_long)|uniprotkb:Diacylglycerol cholinephosphotransferase 1(gene name synonym)|uniprotkb:Sn-1,2-diacylglycerol cholinephosphotransferase(gene name synonym)|uniprotkb:N1218(orf name)|uniprotkb:N1867(orf name)|uniprotkb:YNL130C(locus name)|uniprotkb:CPT1(gene name)|psi-mi:CPT1(display_short)|uniprotkb:Aminoalcohol phosphotransferase CPT1(gene name synonym) psi-mi:ept1_yeast(display_long)|uniprotkb:EPT1(gene name)|psi-mi:EPT1(display_short)|uniprotkb:Aminoalcohol phosphotransferase EPT1(gene name synonym)|uniprotkb:YHR123W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318781|imex:IM-26944-361 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005074|refseq:NP_014269.4|dip:DIP-7848N|mint:P17898|ensemblfungi:YNL130C(gene)|ensemblfungi:YNL130C_mRNA(transcript)|go:"GO:0004142"(diacylglycerol cholinephosphotransferase activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006657"(CDP-choline pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014472(Choline/ethanolaminephosphotransferase)|interpro:IPR043130|reactome:R-SCE-1483191|reactome:R-SCE-1483213|ensemblgenomes:YNL130C(identity) refseq:NP_011991.1|sgd:S000001165|mint:P22140|dip:DIP-5619N|ensemblfungi:YHR123W(gene)|ensemblfungi:YHR123W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004142"(diacylglycerol cholinephosphotransferase activity)|go:"GO:0004307"(ethanolaminephosphotransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006646"(phosphatidylethanolamine biosynthetic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR043130|reactome:R-SCE-1483191|reactome:R-SCE-1483213|interpro:IPR014472(Choline/ethanolaminephosphotransferase)|ensemblgenomes:YHR123W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:PsU8UELFPsbtbzOS6oBnXJAuk/A559292 rogid:CWeN5fKw1tHLle/Vgn+jmL/zrQk559292 rigid:cfvCSbgRZoDpyqKmb4ZXoIbaCsc false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38009 uniprotkb:P54113 intact:EBI-14223|ensemblfungi:YMR120C|uniprotkb:D6VZU3 intact:EBI-14213|uniprotkb:E9PAG6|ensemblfungi:YLR028C|uniprotkb:D6VY30 psi-mi:pur92_yeast(display_long)|uniprotkb:ADE17(gene name)|psi-mi:ADE17(display_short)|uniprotkb:YM8564.02C(orf name)|uniprotkb:YMR120C(locus name) psi-mi:pur91_yeast(display_long)|uniprotkb:ADE16(gene name)|psi-mi:ADE16(display_short)|uniprotkb:YLR028C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318853|imex:IM-26944-191 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013839.1|sgd:S000004727|ensemblfungi:YMR120C(gene)|ensemblfungi:YMR120C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|reactome:R-SCE-73817|interpro:IPR036914|mint:P38009|dip:DIP-6288N|ensemblgenomes:YMR120C(identity) mint:P54113|refseq:NP_013128.1|sgd:S000004018|ensemblfungi:YLR028C(gene)|ensemblfungi:YLR028C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|interpro:IPR036914|dip:DIP-4657N|ensemblgenomes:YLR028C(identity) - crc64:8ABA71761B512242 - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:Bwp78WXy91CpBBXEqmM7MQV7XJk559292 rogid:SbZvY+c2tg098pE/sezKQp+3cFE559292 rigid:4p+2fbkcYZWPnZ/Hz+TVa+/s+Xw false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12043 uniprotkb:P36165 intact:EBI-34845|uniprotkb:Q7LH13|uniprotkb:D6W2E4|ensemblfungi:YOR081C intact:EBI-26531|uniprotkb:D6VXE9|ensemblfungi:YKR089C psi-mi:tgl5_yeast(display_long)|uniprotkb:TGL5(gene name)|psi-mi:TGL5(display_short)|uniprotkb:STC2(gene name synonym)|uniprotkb:YOR29-32(orf name)|uniprotkb:YOR2964C(orf name)|uniprotkb:YOR081C(locus name)|uniprotkb:Lipase 5(gene name synonym) psi-mi:tgl4_yeast(display_long)|uniprotkb:YKR089C(locus name)|uniprotkb:YKR409(orf name)|uniprotkb:TGL4(gene name)|psi-mi:TGL4(display_short)|uniprotkb:STC1(gene name synonym)|uniprotkb:Lipase 4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318841|imex:IM-26944-435 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014724.1|sgd:S000005607|mint:Q12043|dip:DIP-6280N|ensemblfungi:YOR081C(gene)|ensemblfungi:YOR081C_mRNA(transcript)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042171"(lysophosphatidic acid acyltransferase activity)|interpro:IPR002641(Patatin)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR021771|ensemblgenomes:YOR081C(identity) refseq:NP_013015.1|sgd:S000001797|mint:P36165|dip:DIP-5588N|ensemblfungi:YKR089C(gene)|ensemblfungi:YKR089C_mRNA(transcript)|go:"GO:0004771"(sterol esterase activity)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0007114"(cell budding)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042171"(lysophosphatidic acid acyltransferase activity)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|interpro:IPR002641(Patatin)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR021771|ensemblgenomes:YKR089C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:ccHxygbWfyyQXKaSbOL4iYhikms559292 rogid:VEfeOj6QZCY2MIMeme5kaVZBQx8559292 rigid:0S1qggrwBpCfpH7+pxbbm9xI2Cg false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53955 uniprotkb:P40485 intact:EBI-28706|uniprotkb:Q2VQW4|uniprotkb:D6W1D2|ensemblfungi:YNL047C intact:EBI-25172|uniprotkb:D6VVI2|ensemblfungi:YIL105C psi-mi:slm2_yeast(display_long)|uniprotkb:YNL047C(locus name)|uniprotkb:N2515(orf name)|uniprotkb:YNL2515P(orf name)|uniprotkb:SLM2(gene name)|psi-mi:SLM2(display_short)|uniprotkb:LIT1(gene name synonym)|uniprotkb:Synthetic lethal with MSS4 protein 2(gene name synonym)|uniprotkb:TORC2 effector protein SLM2(gene name synonym) psi-mi:slm1_yeast(display_long)|uniprotkb:TORC2 effector protein SLM1(gene name synonym)|uniprotkb:Synthetic lethal with MSS4 protein 1(gene name synonym)|uniprotkb:YIL105C(locus name)|uniprotkb:SLM1(gene name)|psi-mi:SLM1(display_short)|uniprotkb:LIT2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318805|imex:IM-26944-285 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004992|refseq:NP_014351.3|dip:DIP-1269N|mint:P53955|ensemblfungi:YNL047C(gene)|ensemblfungi:YNL047C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031929"(TOR signaling)|go:"GO:0031932"(TORC2 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR033191|interpro:IPR043453|ensemblgenomes:YNL047C(identity) refseq:NP_012161.1|sgd:S000001367|mint:P40485|dip:DIP-1353N|ensemblfungi:YIL105C(gene)|ensemblfungi:YIL105C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031929"(TOR signaling)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070941"(eisosome assembly)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR033191|interpro:IPR043453|rcsb pdb:3NSU|rcsb pdb:4A5K|rcsb pdb:4A6F|rcsb pdb:4A6H|rcsb pdb:4A6K|ensemblgenomes:YIL105C(identity) - crc64:85E65FE60312B875 crc64:849C82CC0960014B figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:z4U8XXxSP0OQE589yaovSrrcVwg559292 rogid:f0Gtntpff7Oav37jlVaggG2VI30559292 rigid:ip8e6wl47SGupdo9ZpEmYBXI1FE false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36122 uniprotkb:P40955 intact:EBI-26374|uniprotkb:D6VX92|ensemblfungi:YKR027W intact:EBI-4649|uniprotkb:D6VW85|ensemblfungi:YJL099W psi-mi:bch2_yeast(display_long)|uniprotkb:YKR027W(locus name)|uniprotkb:BUD7 and CHS6 homolog 2(gene name synonym)|uniprotkb:BCH2(gene name)|psi-mi:BCH2(display_short)|uniprotkb:FMP50(gene name synonym) psi-mi:chs6_yeast(display_long)|uniprotkb:CHS6(gene name)|psi-mi:CHS6(display_short)|uniprotkb:CSD3(gene name synonym)|uniprotkb:YJL099W(locus name)|uniprotkb:J0838(orf name)|uniprotkb:Protein CSD3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318817|imex:IM-26944-623 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001735|interpro:IPR015374(Chs5p-Arf1p binding)|interpro:IPR011990(Tetratricopeptide-like helical)|refseq:NP_012952.3|mint:P36122|ensemblfungi:YKR027W(gene)|ensemblfungi:YKR027W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0034044"(exomer complex)|go:"GO:0034221"(fungal-type cell wall chitin biosynthetic process)|ensemblgenomes:YKR027W(identity) refseq:NP_012436.1|sgd:S000003635|dip:DIP-5682N|ensemblfungi:YJL099W(gene)|ensemblfungi:YJL099W_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0034044"(exomer complex)|go:"GO:0034221"(fungal-type cell wall chitin biosynthetic process)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015374(Chs5p-Arf1p binding)|rcsb pdb:4WJW|rcsb pdb:4YG8|ensemblgenomes:YJL099W(identity) - - crc64:BD92DADA3D5396BC figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:qslkZkP7uV5VCA3xouTfbs5IW9Q559292 rogid:Y8OojYpAni4fbeoZN5eaJaBGISM559292 rigid:pmsYYTHE9AvodqCuIIkCkvp1yn0 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08438 uniprotkb:P36024 intact:EBI-30482|uniprotkb:O00019|uniprotkb:D6W2B8|ensemblfungi:YOR054C intact:EBI-17250|uniprotkb:D6VXD3|ensemblfungi:YKR072C psi-mi:vhs3_yeast(display_long)|uniprotkb:Viable in a HAL3 SIT4 background protein 3(gene name synonym)|uniprotkb:VHS3(gene name)|psi-mi:VHS3(display_short)|uniprotkb:YOR054C(locus name)|uniprotkb:YOR29-05(orf name) psi-mi:sis2_yeast(display_long)|uniprotkb:SIS2(gene name)|psi-mi:SIS2(display_short)|uniprotkb:HAL3(gene name synonym)|uniprotkb:YKR072C(locus name)|uniprotkb:Halotolerance protein HAL3(gene name synonym)|uniprotkb:Sit4 suppressor 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318829|imex:IM-26944-433 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014697.1|sgd:S000005580|dip:DIP-4172N|mint:Q08438|ensemblfungi:YOR054C(gene)|ensemblfungi:YOR054C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0007049"(cell cycle)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0030004"(cellular monovalent inorganic cation homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|ensemblgenomes:YOR054C(identity) refseq:NP_012998.1|sgd:S000001780|ensemblfungi:YKR072C(gene)|ensemblfungi:YKR072C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003824"(catalytic activity)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0009651"(response to salt stress)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|dip:DIP-2521N|mint:P36024|ensemblgenomes:YKR072C(identity) - crc64:A97623473CB6F605 - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:xBrkL/88mlDFkk10q3ASQnr0rv0559292 rogid:oiDiGYmZy7PE7zchnyTa2x4g9zo559292 rigid:g6uo5MivvWVo5qnpBLk0rVGtZBE false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12123 uniprotkb:Q06151 intact:EBI-38701|uniprotkb:D6W2M9|ensemblfungi:YOR173W intact:EBI-38973|uniprotkb:Q6Q5L1|uniprotkb:D6VYR7|ensemblfungi:YLR270W psi-mi:dcs2_yeast(display_long)|uniprotkb:Histidine triad protein(gene name synonym)|uniprotkb:DCS2(gene name)|psi-mi:DCS2(display_short)|uniprotkb:Protein Dcs2p(gene name synonym)|uniprotkb:O3625(orf name)|uniprotkb:YOR173W(locus name) psi-mi:dcps_yeast(display_long)|uniprotkb:DCS-1(gene name synonym)|uniprotkb:Hint-related 7meGMP-directed hydrolase 1(gene name synonym)|uniprotkb:DCS1(gene name)|psi-mi:DCS1(display_short)|uniprotkb:Scavenger mRNA-decapping enzyme DcpS(gene name synonym)|uniprotkb:YLR270W(locus name)|uniprotkb:Protein Dcs1p(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318865|imex:IM-26944-101 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014816.2|sgd:S000005699|mint:Q12123|dip:DIP-4135N|ensemblfungi:YOR173W(gene)|ensemblfungi:YOR173W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007584"(response to nutrient)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009408"(response to heat)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0090342"(regulation of cell aging)|interpro:IPR008594(Scavenger mRNA decapping enzyme)|interpro:IPR011145(Scavenger mRNA decapping enzyme, N-terminal)|interpro:IPR019808|interpro:IPR036265|ensemblgenomes:YOR173W(identity) refseq:NP_013372.1|sgd:S000004260|mint:Q06151|dip:DIP-1480N|ensemblfungi:YLR270W(gene)|ensemblfungi:YLR270W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007584"(response to nutrient)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009408"(response to heat)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0031086"(nuclear-transcribed mRNA catabolic process, deadenylation-independent decay)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044692"(exoribonuclease activator activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0090342"(regulation of cell aging)|go:"GO:1901919"(positive regulation of exoribonuclease activity)|interpro:IPR008594(Scavenger mRNA decapping enzyme)|interpro:IPR011145(Scavenger mRNA decapping enzyme, N-terminal)|interpro:IPR019808|interpro:IPR036265|rcsb pdb:5BV3|rcsb pdb:6TRQ|reactome:R-SCE-429958|ensemblgenomes:YLR270W(identity) - crc64:B76D89C0816019A4 crc64:06A57C2344A3580A figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:aQPcvWgnqKehPYywuexsUkmjU9Q559292 rogid:63HqohkJUuNuZVKy4HcD1f0gGCg559292 rigid:pily5hY7v8hqzDFwVnYJPZ/CsMk false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50094 uniprotkb:P50095 intact:EBI-9195|ensemblfungi:YML056C|uniprotkb:Q2VQW8|uniprotkb:D6VZB8 intact:EBI-9190|ensemblfungi:YLR432W|uniprotkb:D6VZ67 psi-mi:imdh4_yeast(display_long)|uniprotkb:IMD4(gene name)|psi-mi:IMD4(display_short)|uniprotkb:YM9958.06C(orf name)|uniprotkb:YML056C(locus name) psi-mi:imdh3_yeast(display_long)|uniprotkb:IMD3(gene name)|psi-mi:IMD3(display_short)|uniprotkb:L9753.4(orf name)|uniprotkb:YLR432W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318877|imex:IM-26944-529 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML056C(gene)|ensemblfungi:YML056C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|reactome:R-SCE-6798695|reactome:R-SCE-73817|refseq:NP_013656.1|sgd:S000004520|dip:DIP-6458N|mint:P50094|ensemblgenomes:YML056C(identity) ensemblfungi:YLR432W(gene)|ensemblfungi:YLR432W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|reactome:R-SCE-6798695|reactome:R-SCE-73817|refseq:NP_013536.3|sgd:S000004424|dip:DIP-1947N|mint:P50095|ensemblgenomes:YLR432W(identity) - crc64:A73D1E4EFE8AEAD9 crc64:A0C84C22527AAEA6 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:S70ravpil5p+waXS1zst4Ii27dY559292 rogid:UUEyn+zhL8Z1aasK3r/inGhtO1c559292 rigid:gwC+jW4uS2Uppr5O3GHhTj871WM false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P12683 uniprotkb:P12684 intact:EBI-8377|uniprotkb:D6W0K8|ensemblfungi:YML075C intact:EBI-8384|uniprotkb:E9P8X3|uniprotkb:D6VZ84|ensemblfungi:YLR450W psi-mi:hmdh1_yeast(display_long)|uniprotkb:YML075C(locus name)|uniprotkb:HMG1(gene name)|psi-mi:HMG1(display_short) psi-mi:hmdh2_yeast(display_long)|uniprotkb:L9324.2(orf name)|uniprotkb:YLR450W(locus name)|uniprotkb:HMG2(gene name)|psi-mi:HMG2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318901|imex:IM-26944-625 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013636.1|sgd:S000004540|mint:P12683|dip:DIP-4529N|ensemblfungi:YML075C(gene)|ensemblfungi:YML075C_mRNA(transcript)|go:"GO:0004420"("hydroxymethylglutaryl-CoA reductase (NADPH) activity")|go:"GO:0005635"(nuclear envelope)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008299"(isoprenoid biosynthetic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0019287"(isopentenyl diphosphate biosynthetic process, mevalonate pathway)|go:"GO:0034399"(nuclear periphery)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR002202(Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic)|interpro:IPR004554(Hydroxymethylglutaryl-CoA reductase, class I, catalytic)|interpro:IPR009023(Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding)|interpro:IPR009029(Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding)|interpro:IPR023074|interpro:IPR023076|interpro:IPR023282|interpro:IPR025583|reactome:R-SCE-191273|ensemblgenomes:YML075C(identity) refseq:NP_013555.1|sgd:S000004442|mint:P12684|dip:DIP-6277N|ensemblfungi:YLR450W(gene)|ensemblfungi:YLR450W_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004420"("hydroxymethylglutaryl-CoA reductase (NADPH) activity")|go:"GO:0005635"(nuclear envelope)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008299"(isoprenoid biosynthetic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0034399"(nuclear periphery)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR002202(Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic)|interpro:IPR004554(Hydroxymethylglutaryl-CoA reductase, class I, catalytic)|interpro:IPR009023(Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding)|interpro:IPR009029(Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding)|interpro:IPR023074|interpro:IPR023076|interpro:IPR023282|interpro:IPR025583|ensemblgenomes:YLR450W(identity) - - crc64:1FD9DCD3AC01B15E figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:S+uIZsMovFNW2+PxvV7m76Jbh+o559292 rogid:6q1hM5csy4DSYUsSGyTr8M6b9r0559292 rigid:Hz3lN9+lbJc7Nrj6KunRgryHPjc false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38911 uniprotkb:Q06205 intact:EBI-6951|uniprotkb:D6W0K9|ensemblfungi:YML074C intact:EBI-6956|uniprotkb:D6VZ83|ensemblfungi:YLR449W psi-mi:fkbp3_yeast(display_long)|uniprotkb:YML074C(locus name)|uniprotkb:FPR3(gene name)|psi-mi:FPR3(display_short)|uniprotkb:NPI46(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Proline rotamase(gene name synonym)|uniprotkb:Nucleolar proline isomerase(gene name synonym)|uniprotkb:FKBP-70(gene name synonym) psi-mi:fkbp4_yeast(display_long)|uniprotkb:FPR4(gene name)|psi-mi:FPR4(display_short)|uniprotkb:YLR449W(locus name)|uniprotkb:L9324.3(orf name)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:Histone proline isomerase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318889|imex:IM-26944-437 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013637.1|sgd:S000004539|dip:DIP-6578N|ensemblfungi:YML074C(gene)|ensemblfungi:YML074C_mRNA(transcript)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR023566|interpro:IPR041232|ensemblgenomes:YML074C(identity) sgd:S000004441|refseq:NP_013554.3|dip:DIP-909N|mint:Q06205|ensemblfungi:YLR449W(gene)|ensemblfungi:YLR449W_mRNA(transcript)|go:"GO:0000412"(histone peptidyl-prolyl isomerization)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR023566|interpro:IPR041232|rcsb pdb:4BF8|ensemblgenomes:YLR449W(identity) - crc64:A01D24DE0078FE11 crc64:CF90C6714F04572E figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:4xZebf94akWQyMgPLbH6ExNGjoY559292 rogid:rDmDSGEgRbtgkLBoJTzmzxxY7B4559292 rigid:gtgkkxFhLnG/KFfcilKsuHcS9Y8 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32798 uniprotkb:P20107 intact:EBI-5006|uniprotkb:D6W314|ensemblfungi:YOR316C intact:EBI-29667|uniprotkb:D6W070|ensemblfungi:YMR243C psi-mi:cot1_yeast(display_long)|uniprotkb:COT1(gene name)|psi-mi:COT1(display_short)|uniprotkb:O6131(orf name)|uniprotkb:YOR316C(locus name) psi-mi:zrc1_yeast(display_long)|uniprotkb:ZRC1(gene name)|psi-mi:ZRC1(display_short)|uniprotkb:YM9408.05C(orf name)|uniprotkb:YMR243C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318949|imex:IM-26944-531 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005843|refseq:NP_014961.3|dip:DIP-7554N|mint:P32798|ensemblfungi:YOR316C(gene)|ensemblfungi:YOR316C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006824"(cobalt ion transport)|go:"GO:0006829"(zinc ion transport)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0015087"(cobalt ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|reactome:R-SCE-425410|ensemblgenomes:YOR316C(identity) refseq:NP_013970.1|sgd:S000004856|dip:DIP-2030N|mint:P20107|ensemblfungi:YMR243C(gene)|ensemblfungi:YMR243C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|reactome:R-SCE-425410|reactome:R-SCE-435368|ensemblgenomes:YMR243C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:HEIg6lhS698E9H3BJeESYAipNwA559292 rogid:ZZlCJ2Xj5Hiumdl3BNStZFS9qM4559292 rigid:4brok8qxir9FTn7Sb3de9BeVDyQ false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12344 uniprotkb:Q04322 intact:EBI-38508|uniprotkb:D6W3C2|ensemblfungi:YPL249C intact:EBI-27427|uniprotkb:D6W016|ensemblfungi:YMR192W psi-mi:gyp5_yeast(display_long)|uniprotkb:GYP5(gene name)|psi-mi:GYP5(display_short)|uniprotkb:YPL249C(locus name) psi-mi:gyl1_yeast(display_long)|uniprotkb:YMR192W(locus name)|uniprotkb:YM9646.04(orf name)|uniprotkb:GYL1(gene name)|psi-mi:GYL1(display_short)|uniprotkb:APP2(gene name synonym)|uniprotkb:GYP5-like protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318937|imex:IM-26944-103 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015075.1|sgd:S000006170|mint:Q12344|dip:DIP-8946N|ensemblfungi:YPL249C(gene)|ensemblfungi:YPL249C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|ensemblgenomes:YPL249C(identity) mint:Q04322|refseq:NP_013917.1|sgd:S000004804|dip:DIP-2891N|ensemblfungi:YMR192W(gene)|ensemblfungi:YMR192W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0017157"(regulation of exocytosis)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|ensemblgenomes:YMR192W(identity) - crc64:67BAAC39B2A51859 - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:oHovDOB1prsJfQnQBfIBxNOFdNw559292 rogid:JXXEUKwB+ysZExb+8We4yeNrftM559292 rigid:o+JsWEIAq0/lN0vmSg5GylNi6nc false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02829 uniprotkb:P15108 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 intact:EBI-8666|ensemblfungi:YMR186W|uniprotkb:D6W010 psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:hsc82_yeast(display_long)|uniprotkb:HSC82(gene name)|psi-mi:HSC82(display_short)|uniprotkb:YMR186W(locus name)|uniprotkb:YM8010.16(orf name)|uniprotkb:Heat shock protein Hsp90 constitutive isoform(gene name synonym)|uniprotkb:82 kDa heat shock cognate protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318925|imex:IM-26944-441 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N|ensemblgenomes:YPL240C(identity) interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:6XLB|rcsb pdb:6XLC|rcsb pdb:6XLD|rcsb pdb:6XLE|rcsb pdb:6XLF|ensemblfungi:YMR186W(gene)|ensemblfungi:YMR186W_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000723"(telomere maintenance)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|rcsb pdb:6XLG|rcsb pdb:6XLH|reactome:R-SCE-1474151|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-9009391|refseq:NP_013911.1|sgd:S000004798|mint:P15108|dip:DIP-1524N|ensemblgenomes:YMR186W(identity) - crc64:D7C35676D668FB63 crc64:DBD41524091B1F9B figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 rogid:A0Na3L9N4cl7acd9lSGiwKAYK1o559292 rigid:mkf5N3WU6LcBcEt0O0SlG6HEVaI false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38426 uniprotkb:P38427 intact:EBI-19448|uniprotkb:D6W087|uniprotkb:Q6B1W2|ensemblfungi:YMR261C intact:EBI-19638|uniprotkb:D6W0I5|ensemblfungi:YML100W psi-mi:tps3_yeast(display_long)|uniprotkb:TPS3(gene name)|psi-mi:TPS3(display_short)|uniprotkb:YMR261C(locus name)|uniprotkb:YM8156.03C(orf name)|uniprotkb:Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 115 kDa subunit(gene name synonym) psi-mi:tsl1_yeast(display_long)|uniprotkb:TSL1(gene name)|psi-mi:TSL1(display_short)|uniprotkb:YML100W(locus name)|uniprotkb:Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 123 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318913|imex:IM-26944-193 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013988.1|sgd:S000004874|ensemblfungi:YMR261C(gene)|ensemblfungi:YMR261C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005946"("alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)")|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0016311"(dephosphorylation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR001830(Glycosyl transferase, family 20)|interpro:IPR003337(Trehalose-phosphatase)|interpro:IPR036412|dip:DIP-891N|mint:P38426|ensemblgenomes:YMR261C(identity) refseq:NP_013608.1|sgd:S000004566|ensemblfungi:YML100W(gene)|ensemblfungi:YML100W_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005946"("alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)")|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0016311"(dephosphorylation)|go:"GO:0030234"(enzyme regulator activity)|interpro:IPR001830(Glycosyl transferase, family 20)|interpro:IPR003337(Trehalose-phosphatase)|interpro:IPR036412|dip:DIP-753N|mint:P38427|ensemblgenomes:YML100W(identity) - - crc64:EA0A8A86AF178F04 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:aY+Gu2+xxYxfe40pjJ1KTaYbDxM559292 rogid:c83+6JC2tSJt4Z06mI3KDmHI1iM559292 rigid:dxxYNbt5LFQ2eZOAZZ7swyPpip8 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01560 uniprotkb:P25555 intact:EBI-12114|uniprotkb:D6VT60|ensemblfungi:YDR432W intact:EBI-7410|uniprotkb:D6VR01|ensemblfungi:YCL011C psi-mi:nop3_yeast(display_long)|uniprotkb:MTR13(gene name synonym)|uniprotkb:MTS1(gene name synonym)|uniprotkb:Mitochondrial targeting suppressor 1 protein(gene name synonym)|uniprotkb:Nuclear polyadenylated RNA-binding protein 1(gene name synonym)|uniprotkb:NPL3(gene name)|psi-mi:NPL3(display_short)|uniprotkb:NAB1(gene name synonym)|uniprotkb:YDR432W(locus name)|uniprotkb:D9461.19(orf name)|uniprotkb:NOP3(gene name synonym) psi-mi:gbp2_yeast(display_long)|uniprotkb:GBP2(gene name)|psi-mi:GBP2(display_short)|uniprotkb:RLF6(gene name synonym)|uniprotkb:YCL011C(locus name)|uniprotkb:YCL11C(orf name)|uniprotkb:RAP1 localization factor 6(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319052|imex:IM-26944-197 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDR432W(gene)|ensemblfungi:YDR432W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006415"(translational termination)|go:"GO:0008143"("poly(A) binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:2000805"("negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034166|interpro:IPR035979|rcsb pdb:2JD5|rcsb pdb:2JVO|rcsb pdb:2JVR|rcsb pdb:2OSQ|rcsb pdb:2OSR|refseq:NP_010720.3|sgd:S000002840|dip:DIP-6464N|ensemblgenomes:YDR432W(identity) refseq:NP_009916.1|sgd:S000000517|ensemblfungi:YCL011C(gene)|ensemblfungi:YCL011C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|mint:P25555|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:1990904"(ribonucleoprotein complex)|dip:DIP-2735N|go:"GO:2000815"(regulation of mRNA stability involved in response to oxidative stress)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:2MZQ|ensemblgenomes:YCL011C(identity) - crc64:024439E4B6578787 crc64:5341D7A0E07F208C figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:R/g8r9x82rdG8AThC5VQcbgY6u4559292 rogid:0fURlZ6JcMWvS0mSxpR2LZ8uDrE559292 rigid:HzTgQU80t2OWIfB4zMWWDkFVXuM false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12335 uniprotkb:P25349 intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 intact:EBI-21840|uniprotkb:D6VR14|ensemblfungi:YCR004C psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:ycp4_yeast(display_long)|uniprotkb:YCR042(orf name)|uniprotkb:YCR4C(orf name)|uniprotkb:YCR004C(locus name)|uniprotkb:YCP4(gene name)|psi-mi:YCP4(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319064|imex:IM-26944-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N|ensemblgenomes:YDR032C(identity) refseq:NP_009930.1|sgd:S000000597|dip:DIP-1781N|ensemblfungi:YCR004C(gene)|ensemblfungi:YCR004C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|ensemblgenomes:YCR004C(identity) - crc64:1056E7A1F3E82288 - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 rogid:l7d0Z9G9F/3vOnI80MPKdsll1aI559292 rigid:bHXQKmNq5b9C9KtPiDu97Y+U1GU false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32915 uniprotkb:P38353 intact:EBI-16400|ensemblfungi:YLR378C|uniprotkb:D6VZ14 intact:EBI-18175|uniprotkb:D6VQS8|ensemblfungi:YBR283C psi-mi:sc61a_yeast(display_long)|uniprotkb:Sec61 complex subunit SEC61(gene name synonym)|uniprotkb:L3502.5(orf name)|uniprotkb:YLR378C(locus name)|uniprotkb:SEC61(gene name)|psi-mi:SEC61(display_short)|uniprotkb:Sec61 complex subunit alpha(gene name synonym) psi-mi:ssh1_yeast(display_long)|uniprotkb:SSH1(gene name)|psi-mi:SSH1(display_short)|uniprotkb:Ssh1 complex subunit alpha(gene name synonym)|uniprotkb:Ssh1 complex subunit SSH1(gene name synonym)|uniprotkb:YBR2020(orf name)|uniprotkb:YBR283C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319040|imex:IM-26944-195 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070843"(misfolded protein transport)|go:"GO:1904680"(peptide transmembrane transporter activity)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:6N3Q|rcsb pdb:6ND1|rcsb pdb:7AFT|rcsb pdb:7KAH|rcsb pdb:7KAI|rcsb pdb:7KAJ|rcsb pdb:7KAO|rcsb pdb:7KAP|rcsb pdb:7KAQ|rcsb pdb:7KAR|rcsb pdb:7KAS|rcsb pdb:7KAT|rcsb pdb:7KAU|rcsb pdb:7KB5|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|ensemblfungi:YLR378C(gene)|ensemblfungi:YLR378C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015450"(protein-transporting ATPase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|refseq:NP_013482.1|sgd:S000004370|dip:DIP-2433N|mint:P32915|ensemblgenomes:YLR378C(identity) refseq:NP_009842.1|sgd:S000000487|ensemblfungi:YBR283C(gene)|ensemblfungi:YBR283C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:2WW9|rcsb pdb:2WWA|dip:DIP-4962N|mint:P38353|ensemblgenomes:YBR283C(identity) - - crc64:48267EEA3E0191BD figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:Gi0aAi/lO9gi5h6LMgke4advNsM559292 rogid:76wvZIdv7W5BQn6wI+sHOGQAyuc559292 rigid:B9+rfc4HejFPHcTjrdVwUndp3WM false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40088 uniprotkb:P38310 intact:EBI-7138|uniprotkb:D3DM52|ensemblfungi:YER145C intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W psi-mi:ftr1_yeast(display_long)|uniprotkb:FTR1(gene name)|psi-mi:FTR1(display_short)|uniprotkb:YER145C(locus name) psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319028|imex:IM-26944-287 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-5376N|refseq:NP_011072.1|sgd:S000000947|mint:P40088|ensemblfungi:YER145C(gene)|ensemblfungi:YER145C_mRNA(transcript)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:1901684"(arsenate ion transmembrane transport)|interpro:IPR004923(Iron permease FTR1)|interpro:IPR005217(Conserved hypothetical protein CHP00145)|ensemblgenomes:YER145C(identity) refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1)|ensemblgenomes:YBR207W(identity) - - crc64:7B4E620ABC39A053 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:fhDKp2YYbK7C+ACjHx1AuPCyts4559292 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 rigid:Nru5IGj6UNGc37K7TjbdKi47FUY false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12166 uniprotkb:P06208-1 intact:EBI-37359|uniprotkb:D6W2G7|ensemblfungi:YOR108W intact:EBI-21318961 psi-mi:leu9_yeast(display_long)|uniprotkb:LEU9(gene name)|psi-mi:LEU9(display_short)|uniprotkb:YOR3227w(orf name)|uniprotkb:Alpha-isopropylmalate synthase 2(gene name synonym)|uniprotkb:Alpha-IPM synthase 2(gene name synonym)|uniprotkb:Alpha-isopropylmalate synthase II(gene name synonym)|uniprotkb:YOR108W(locus name) psi-mi:p062081(display_long)|uniprotkb:LEU4(gene name)|psi-mi:LEU4(display_short)|uniprotkb:N2173(orf name)|uniprotkb:YNL104C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318968|imex:IM-26944-627 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014751.1|sgd:S000005634|mint:Q12166|dip:DIP-4153N|ensemblfungi:YOR108W(gene)|ensemblfungi:YOR108W_mRNA(transcript)|go:"GO:0003852"(2-isopropylmalate synthase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0009082"(branched-chain amino acid biosynthetic process)|go:"GO:0009098"(leucine biosynthetic process)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR002034(Alpha-isopropylmalate/homocitrate synthase, conserved site)|interpro:IPR005668(Yeast 2-isopropylmalate synthase)|interpro:IPR013709("2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain")|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR036230|interpro:IPR039371|ensemblgenomes:YOR108W(identity) uniprotkb:P06208-1(isoform-parent)|ensemblgenomes:YNL104C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:xem/K524HzAGsD4IT+y2KU/l7gI559292 rogid:qysUHIGQ5iB9CaOQvK2/+iVHuyQ559292 rigid:iJt24QLrRMwck3tocexJ1sMvl5U false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04651 uniprotkb:P39727 intact:EBI-27850|uniprotkb:E9PAD9|uniprotkb:D6VZA6|ensemblfungi:YML067C intact:EBI-20659|uniprotkb:D6VPH4|ensemblfungi:YAL042W psi-mi:erv41_yeast(display_long)|uniprotkb:YML067C(locus name)|uniprotkb:ERV41(gene name)|psi-mi:ERV41(display_short) psi-mi:erv46_yeast(display_long)|uniprotkb:FUN9(orf name)|uniprotkb:YAL042W(locus name)|uniprotkb:ERV46(gene name)|psi-mi:ERV46(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319004|imex:IM-26944-535 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013644.1|sgd:S000004532|dip:DIP-6791N|mint:Q04651|ensemblfungi:YML067C(gene)|ensemblfungi:YML067C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542|rcsb pdb:3ZLC|ensemblgenomes:YML067C(identity) refseq:NP_009358.1|sgd:S000000040|ensemblfungi:YAL042W(gene)|ensemblfungi:YAL042W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542|dip:DIP-3792N|mint:P39727|ensemblgenomes:YAL042W(identity) - - crc64:FB7BC171B88BB5EA figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:IpGpvBxckHz1ExXTnTsKEHU2su8559292 rogid:tVyaLk7odK7bfnaz1FMv0E9lgtU559292 rigid:RxRVkGV0ee3X9a8C2VOpR6zOqbo false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P24784 uniprotkb:P06634 intact:EBI-5596|uniprotkb:P20446|uniprotkb:D6W3P9|ensemblfungi:YPL119C intact:EBI-5744|uniprotkb:D6W2R0|ensemblfungi:YOR204W psi-mi:dbp1_yeast(display_long)|uniprotkb:DBP1(gene name)|psi-mi:DBP1(display_short)|uniprotkb:YPL119C(locus name)|uniprotkb:LPH8C(orf name)|uniprotkb:DEAD box protein 1(gene name synonym)|uniprotkb:Helicase CA1(gene name synonym) psi-mi:ded1_yeast(display_long)|uniprotkb:DED1(gene name)|psi-mi:DED1(display_short)|uniprotkb:SPP81(gene name synonym)|uniprotkb:YOR204W(locus name)|uniprotkb:DEAD box protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318992|imex:IM-26944-533 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015206.1|sgd:S000006040|dip:DIP-2576N|mint:P24784|ensemblfungi:YPL119C(gene)|ensemblfungi:YPL119C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044763|ensemblgenomes:YPL119C(identity) sgd:S000005730|refseq:NP_014847.3|dip:DIP-5820N|mint:P06634|ensemblfungi:YOR204W(gene)|ensemblfungi:YOR204W_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044763|reactome:R-SCE-6798695|ensemblgenomes:YOR204W(identity) - - crc64:B6722D94C03BFA4B figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:8TFwSQq3dopTasOH0G/KZ12DDGE559292 rogid:FkldumX6m5gBuuaG09aTJ0kuMZM559292 rigid:ViW4daqDyjZldSTusJ5qfTWmLYs false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02969 uniprotkb:Q08580 intact:EBI-37452|uniprotkb:Q6B2A9|uniprotkb:D6W3Q5|ensemblfungi:YPL112C intact:EBI-34476|uniprotkb:D6W2Q2|ensemblfungi:YOR193W psi-mi:pex25_yeast(display_long)|uniprotkb:YPL112C(locus name)|uniprotkb:PEX25(gene name)|psi-mi:PEX25(display_short)|uniprotkb:Peroxin-25(gene name synonym) psi-mi:pex27_yeast(display_long)|uniprotkb:PEX27(gene name)|psi-mi:PEX27(display_short)|uniprotkb:Peroxin-27(gene name synonym)|uniprotkb:YOR193W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21318980|imex:IM-26944-443 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000006033|refseq:NP_015213.1|dip:DIP-5292N|mint:Q02969|ensemblfungi:YPL112C(gene)|ensemblfungi:YPL112C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0016559"(peroxisome fission)|go:"GO:0044375"(regulation of peroxisome size)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|ensemblgenomes:YPL112C(identity) sgd:S000005719|mint:Q08580|refseq:NP_014836.3|ensemblfungi:YOR193W(gene)|ensemblfungi:YOR193W_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016559"(peroxisome fission)|go:"GO:0044375"(regulation of peroxisome size)|ensemblgenomes:YOR193W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:42Jce4KR0S5WehK1GVfqhG+Cqbo559292 rogid:4KDjn/JFPYAMsOKZxfT5DiKQWyE559292 rigid:vVnRLT8ibKeBGZj8ce7RgqWxRzI false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25376 uniprotkb:P38085 intact:EBI-2357|uniprotkb:D6VQZ1|ensemblfungi:YCL025C intact:EBI-20222|uniprotkb:D6VQ68|ensemblfungi:YBR069C psi-mi:agp1_yeast(display_long)|uniprotkb:AGP1(gene name)|psi-mi:AGP1(display_short)|uniprotkb:YCL025C(locus name)|uniprotkb:YCL25C(orf name)|uniprotkb:Asparagine/glutamine permease(gene name synonym) psi-mi:tat1_yeast(display_long)|uniprotkb:TAT1(gene name)|psi-mi:TAT1(display_short)|uniprotkb:TAP1(gene name synonym)|uniprotkb:VAP1(gene name synonym)|uniprotkb:YBR069C(locus name)|uniprotkb:YBR0710(orf name)|uniprotkb:Tyrosine and tryptophan amino acid transporter 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319016|imex:IM-26944-629 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009905.3|sgd:S000000530|dip:DIP-4973N|mint:P25376|ensemblfungi:YCL025C(gene)|ensemblfungi:YCL025C_mRNA(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015192"(L-phenylalanine transmembrane transporter activity)|go:"GO:0015193"(L-proline transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0098718"(serine import across plasma membrane)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region)|ensemblgenomes:YCL025C(identity) refseq:NP_009625.1|sgd:S000000273|mint:P38085|ensemblfungi:YBR069C(gene)|ensemblfungi:YBR069C_mRNA(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015827"(tryptophan transport)|go:"GO:0015828"(tyrosine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022893"(low-affinity tryptophan transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region)|dip:DIP-4912N|ensemblgenomes:YBR069C(identity) - crc64:8E19A836C2F6C50F crc64:7A575A9BF2A084F8 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:bB5pBnaoMUTwxlz8v5MAjCWc4Mg559292 rogid:J/bUE0sAFk7WkiPOXHMXQHfI618559292 rigid:X/8FCtdFaqViUzLoToVScFfjdjA false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11154 uniprotkb:P32327 intact:EBI-14358|uniprotkb:D6VU79|ensemblfungi:YGL062W intact:EBI-14365|uniprotkb:D6VQL4|ensemblfungi:YBR218C psi-mi:pyc1_yeast(display_long)|uniprotkb:PYV(gene name synonym)|uniprotkb:YGL062W(locus name)|uniprotkb:PYC1(gene name)|psi-mi:PYC1(display_short)|uniprotkb:Pyruvic carboxylase 1(gene name synonym) psi-mi:pyc2_yeast(display_long)|uniprotkb:PYC2(gene name)|psi-mi:PYC2(display_short)|uniprotkb:YBR218C(locus name)|uniprotkb:YBR1507(orf name)|uniprotkb:Pyruvic carboxylase 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319292|imex:IM-26944-111 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL062W(gene)|go:"GO:0004736"(pyruvate carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0009374"(biotin binding)|go:"GO:0046872"(metal ion binding)|ensemblfungi:YGL062W_mRNA(transcript)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR001882(Biotin-binding site)|interpro:IPR003379(Conserved carboxylase region)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR005930(Pyruvate carboxylase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016185(PreATP-grasp-like fold)|reactome:R-SCE-196780|reactome:R-SCE-70263|refseq:NP_011453.1|sgd:S000003030|mint:P11154|dip:DIP-6425N|ensemblgenomes:YGL062W(identity) refseq:NP_009777.1|sgd:S000000422|ensemblfungi:YBR218C(gene)|ensemblfungi:YBR218C_mRNA(transcript)|go:"GO:0004736"(pyruvate carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0009374"(biotin binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR001882(Biotin-binding site)|interpro:IPR003379(Conserved carboxylase region)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR005930(Pyruvate carboxylase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|mint:P32327|dip:DIP-6426N|ensemblgenomes:YBR218C(identity) - crc64:BC7110A8AFB23E04 crc64:AD60DA3A60F5E001 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:YleVCYfwUsqRJy5ua02EuklzpkQ559292 rogid:FvnnWuplwrt91+684m4fpfW2su8559292 rigid:oLwK7o8/13CAY3E++XQ5xwXJCxk false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38426 uniprotkb:P31688 intact:EBI-19448|uniprotkb:D6W087|uniprotkb:Q6B1W2|ensemblfungi:YMR261C intact:EBI-19440|uniprotkb:D6VS60|ensemblfungi:YDR074W psi-mi:tps3_yeast(display_long)|uniprotkb:TPS3(gene name)|psi-mi:TPS3(display_short)|uniprotkb:YMR261C(locus name)|uniprotkb:YM8156.03C(orf name)|uniprotkb:Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 115 kDa subunit(gene name synonym) psi-mi:tps2_yeast(display_long)|uniprotkb:TPS2(gene name)|psi-mi:TPS2(display_short)|uniprotkb:PFK3(gene name synonym)|uniprotkb:YDR074W(locus name)|uniprotkb:YD8554.07(orf name)|uniprotkb:Trehalose-6-phosphate phosphatase(gene name synonym)|uniprotkb:Trehalose synthase complex catalytic subunit TPS2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319076|imex:IM-26944-199 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013988.1|sgd:S000004874|ensemblfungi:YMR261C(gene)|ensemblfungi:YMR261C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005946"("alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)")|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0016311"(dephosphorylation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR001830(Glycosyl transferase, family 20)|interpro:IPR003337(Trehalose-phosphatase)|interpro:IPR036412|dip:DIP-891N|mint:P38426|ensemblgenomes:YMR261C(identity) refseq:NP_010359.1|sgd:S000002481|ensemblfungi:YDR074W(gene)|ensemblfungi:YDR074W_mRNA(transcript)|go:"GO:0004805"(trehalose-phosphatase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005946"("alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)")|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0070413"(trehalose metabolism in response to stress)|interpro:IPR001830(Glycosyl transferase, family 20)|interpro:IPR003337(Trehalose-phosphatase)|interpro:IPR006379(HAD-superfamily hydrolase, subfamily IIB)|interpro:IPR023214|interpro:IPR036412|dip:DIP-823N|mint:P31688|ensemblgenomes:YDR074W(identity) - - crc64:E349672CCCDA9349 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:aY+Gu2+xxYxfe40pjJ1KTaYbDxM559292 rogid:kfEKVrS0+2MOIcLy9XDHbAdFFCI559292 rigid:dCmfkr5wucCtZPPaTiiHLwdZcdI false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23254 uniprotkb:P33315 intact:EBI-19291|uniprotkb:D6W478|ensemblfungi:YPR074C intact:EBI-19297|uniprotkb:D6VQB5|ensemblfungi:YBR117C psi-mi:tkt1_yeast(display_long)|uniprotkb:YP9499.29C(orf name)|uniprotkb:YPR074C(locus name)|uniprotkb:TKL1(gene name)|psi-mi:TKL1(display_short) psi-mi:tkt2_yeast(display_long)|uniprotkb:YBR0912(orf name)|uniprotkb:YBR117C(locus name)|uniprotkb:TKL2(gene name)|psi-mi:TKL2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319268|imex:IM-26944-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015399.1|sgd:S000006278|interpro:IPR029061|interpro:IPR033247|interpro:IPR033248|rcsb pdb:1AY0|rcsb pdb:1GPU|rcsb pdb:1NGS|rcsb pdb:1TKA|rcsb pdb:1TKB|rcsb pdb:1TKC|rcsb pdb:1TRK|interpro:IPR020826|ensemblfungi:YPR074C(gene)|ensemblfungi:YPR074C_mRNA(transcript)|go:"GO:0004802"(transketolase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0046872"(metal ion binding)|interpro:IPR005474(Transketolase, N-terminal)|interpro:IPR005475(Transketolase, central region)|interpro:IPR005478(Bacterial transketolase)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|dip:DIP-6765N|mint:P23254|ensemblgenomes:YPR074C(identity) sgd:S000000321|ensemblfungi:YBR117C(gene)|ensemblfungi:YBR117C_mRNA(transcript)|go:"GO:0004802"(transketolase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0046872"(metal ion binding)|interpro:IPR005474(Transketolase, N-terminal)|interpro:IPR005475(Transketolase, central region)|interpro:IPR005478(Bacterial transketolase)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR020826|interpro:IPR029061|interpro:IPR033247|interpro:IPR033248|refseq:NP_009675.3|dip:DIP-757N|mint:P33315|ensemblgenomes:YBR117C(identity) - crc64:40225EAA23A63835 - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:rRfdYF2q76Mp6FJzwkOGeefxbOQ559292 rogid:Sjs+DFWJRPK+Xd6PoO/CHVNniVE559292 rigid:94pv+/yqRIUvAnGY7Hv23ZLXGjw false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P22202 uniprotkb:P09435 intact:EBI-8621|uniprotkb:D3DM10|ensemblfungi:YER103W intact:EBI-8611|uniprotkb:P18862|uniprotkb:D6VPS7|ensemblfungi:YBL075C psi-mi:hsp74_yeast(display_long)|uniprotkb:YER103W(locus name)|uniprotkb:SSA4(gene name)|psi-mi:SSA4(display_short) psi-mi:hsp73_yeast(display_long)|uniprotkb:YBL06.07(orf name)|uniprotkb:YBL0610(orf name)|uniprotkb:YBL075C(locus name)|uniprotkb:SSA3(gene name)|psi-mi:SSA3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319256|imex:IM-26944-109 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000905|refseq:NP_011029.3|mint:P22202|dip:DIP-3916N|ensemblfungi:YER103W(gene)|ensemblfungi:YER103W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:3UPV|ensemblgenomes:YER103W(identity) refseq:NP_009478.1|sgd:S000000171|mint:P09435|dip:DIP-2266N|ensemblfungi:YBL075C(gene)|ensemblfungi:YBL075C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|ensemblgenomes:YBL075C(identity) - crc64:7A976357AC35C352 crc64:F4B136759B7D4636 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:QiL3U6hhfGX8ulZBYuNAL68zI2s559292 rogid:u3ayjvFHnVNMMrDZdrB7NWaGzBg559292 rigid:kjYO+blRqrPGswWxiGuT609FGak false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38627 uniprotkb:P28274 intact:EBI-20133|uniprotkb:D6VWS2|ensemblfungi:YJR103W intact:EBI-20128|uniprotkb:D6VPW0|ensemblfungi:YBL039C psi-mi:ura8_yeast(display_long)|uniprotkb:URA8(gene name)|psi-mi:URA8(display_short)|uniprotkb:YJR103W(locus name)|uniprotkb:J1962(orf name)|uniprotkb:UTP--ammonia ligase 2(gene name synonym)|uniprotkb:CTP synthetase 2(gene name synonym) psi-mi:ura7_yeast(display_long)|uniprotkb:YBL039C(locus name)|uniprotkb:YBL0410(orf name)|uniprotkb:URA7(gene name)|psi-mi:URA7(display_short)|uniprotkb:UTP--ammonia ligase 1(gene name synonym)|uniprotkb:CTP synthetase 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319244|imex:IM-26944-291 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003864|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0019856"(pyrimidine nucleobase biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044210"('de novo' CTP biosynthetic process)|go:"GO:0097268"(cytoophidium)|interpro:IPR004468(CTP synthase)|interpro:IPR017456(CTP synthase, N-terminal)|interpro:IPR017926|interpro:IPR027417|interpro:IPR029062|interpro:IPR033828|reactome:R-SCE-499943|go:"GO:0003883"(CTP synthase activity)|refseq:NP_012637.4|mint:P38627|ensemblfungi:YJR103W(gene)|ensemblfungi:YJR103W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|dip:DIP-3941N|ensemblgenomes:YJR103W(identity) refseq:NP_009514.1|sgd:S000000135|mint:P28274|ensemblfungi:YBL039C(gene)|ensemblfungi:YBL039C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0003883"(CTP synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0019856"(pyrimidine nucleobase biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044210"('de novo' CTP biosynthetic process)|go:"GO:0097268"(cytoophidium)|interpro:IPR004468(CTP synthase)|interpro:IPR017456(CTP synthase, N-terminal)|interpro:IPR017926|interpro:IPR027417|interpro:IPR029062|interpro:IPR033828|reactome:R-SCE-499943|dip:DIP-2954N|ensemblgenomes:YBL039C(identity) - crc64:6381F30814CC2D57 crc64:EC3766C83B22ED92 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:G2YBZFIatg3KvRcjPSdGc/5JjOM559292 rogid:O/aH071giuopuWAjtGPdWti19NQ559292 rigid:J5NA2gmbAWHM0vMn/euF833YX9k false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53198 uniprotkb:Q05359 intact:EBI-2058104|uniprotkb:D6VUD6|uniprotkb:E9P916|ensemblfungi:YGL002W intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A psi-mi:erp6_yeast(display_long)|uniprotkb:ERP6(gene name)|psi-mi:ERP6(display_short)|uniprotkb:YGL002W(locus name) psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319232|imex:IM-26944-637 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011513.1|sgd:S000002970|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|mint:P53198|ensemblfungi:YGL002W(gene)|ensemblfungi:YGL002W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|reactome:R-SCE-6811434|ensemblgenomes:YGL002W(identity) refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434|ensemblgenomes:YAR002C-A(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:pM23btPgVfhIqmxeV0jxQGSX4/8559292 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 rigid:q0/7fyhKzf+QajF3J70ErU0L76E false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12450 uniprotkb:P39704 intact:EBI-6598|uniprotkb:D6W282|ensemblfungi:YOR016C intact:EBI-6587|uniprotkb:D6VPL1|ensemblfungi:YAL007C psi-mi:erp4_yeast(display_long)|uniprotkb:ERP4(gene name)|psi-mi:ERP4(display_short)|uniprotkb:YOR016C(locus name) psi-mi:erp2_yeast(display_long)|uniprotkb:ERP2(gene name)|psi-mi:ERP2(display_short)|uniprotkb:FUN54(orf name)|uniprotkb:YAL007C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319220|imex:IM-26944-371 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014659.1|sgd:S000005542|mint:Q12450|dip:DIP-7868N|ensemblfungi:YOR016C(gene)|ensemblfungi:YOR016C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|reactome:R-SCE-6811434|ensemblgenomes:YOR016C(identity) refseq:NP_009395.1|sgd:S000000005|mint:P39704|dip:DIP-5808N|ensemblfungi:YAL007C(gene)|ensemblfungi:YAL007C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|reactome:R-SCE-6811434|ensemblgenomes:YAL007C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:An7as6LjEDUYrLvEbua3xSL6bEk559292 rogid:qe1as0AJSSRC8SOKfxboQA2VKtY559292 rigid:tY4FxBS/0vLA1IzGM1DQtDL4MdQ false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33760 uniprotkb:P24004 intact:EBI-13178|uniprotkb:D6W0L8|ensemblfungi:YNL329C intact:EBI-13155|uniprotkb:D6VX03|ensemblfungi:YKL197C psi-mi:pex6_yeast(display_long)|uniprotkb:PEX6(gene name)|psi-mi:PEX6(display_short)|uniprotkb:PAS8(gene name synonym)|uniprotkb:YNL329C(locus name)|uniprotkb:N0310(orf name)|uniprotkb:Peroxin-6(gene name synonym)|uniprotkb:Peroxisome biosynthesis protein PAS8(gene name synonym)|uniprotkb:Peroxisomal assembly protein 8(gene name synonym) psi-mi:pex1_yeast(display_long)|uniprotkb:YKL197C(locus name)|uniprotkb:PEX1(gene name)|psi-mi:PEX1(display_short)|uniprotkb:PAS1(gene name synonym)|uniprotkb:Peroxin-1(gene name synonym)|uniprotkb:Peroxisome biogenesis protein PAS1(gene name synonym)|uniprotkb:Peroxisomal assembly protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319208|imex:IM-26944-107 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014070.1|sgd:S000005273|mint:P33760|dip:DIP-2621N|ensemblfungi:YNL329C(gene)|ensemblfungi:YNL329C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0016562"(protein import into peroxisome matrix, receptor recycling)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0043335"(protein unfolding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|ensemblgenomes:YNL329C(identity) refseq:NP_012724.1|sgd:S000001680|dip:DIP-4266N|ensemblfungi:YKL197C(gene)|ensemblfungi:YKL197C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0016562"(protein import into peroxisome matrix, receptor recycling)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0043335"(protein unfolding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR015342(Peroxisome biogenesis factor 1, N-terminal)|interpro:IPR025653|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|ensemblgenomes:YKL197C(identity) - crc64:736FECB57BBFF8F8 - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:vonluDQS+We5JMYERfce8BzCIVk559292 rogid:dk1kX5xmVl+XC0YkOgFnrrx5wG4559292 rigid:3WZIwzPbiWcG5hcftoN1hMrTls4 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05031 uniprotkb:P36091 intact:EBI-27512|uniprotkb:D6W064|ensemblfungi:YMR238W intact:EBI-2052781|uniprotkb:D6VXP1|uniprotkb:Q66R60|ensemblfungi:YKL046C psi-mi:dfg5_yeast(display_long)|uniprotkb:DFG5(gene name)|psi-mi:DFG5(display_short)|uniprotkb:YMR238W(locus name)|uniprotkb:YM9959.20(orf name)|uniprotkb:Endo-alpha-1->6-D-mannanase DFG5(gene name synonym) psi-mi:dcw1_yeast(display_long)|uniprotkb:Endo-alpha-1->6-D-mannanase DCW1(gene name synonym)|uniprotkb:Defective cell wall 1(gene name synonym)|uniprotkb:YKL259(orf name)|uniprotkb:YKL046C(locus name)|uniprotkb:DCW1(gene name)|psi-mi:DCW1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319196|imex:IM-26944-369 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q05031|refseq:NP_013965.1|sgd:S000004851|dip:DIP-2739N|ensemblfungi:YMR238W(gene)|ensemblfungi:YMR238W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007117"(budding cell bud growth)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008496"(mannan endo-1,6-alpha-mannosidase activity)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0016052"(carbohydrate catabolic process)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0071555"(cell wall organization)|interpro:IPR005198(Glycoside hydrolase, family 76)|interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR014480(Mannan endo-1,6-alpha-mannosidase)|ensemblgenomes:YMR238W(identity) refseq:NP_012878.1|sgd:S000001529|interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR005198(Glycoside hydrolase, family 76)|interpro:IPR014480(Mannan endo-1,6-alpha-mannosidase)|mint:P36091|ensemblfungi:YKL046C(gene)|ensemblfungi:YKL046C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005933"(cellular bud)|go:"GO:0007117"(budding cell bud growth)|go:"GO:0008496"(mannan endo-1,6-alpha-mannosidase activity)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0016052"(carbohydrate catabolic process)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0071555"(cell wall organization)|ensemblgenomes:YKL046C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:nnHGptBCE3g8JbHRaiJvIbe4Nw8559292 rogid:cUTmFkcG9XK4BwQ2VebK5tm10Dw559292 rigid:vz9bV3kb+2w6aMtw7BGHMfLZOyw false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P16862 uniprotkb:P16861 intact:EBI-9435|ensemblfungi:YMR205C|uniprotkb:D6W030 intact:EBI-9428|ensemblfungi:YGR240C|uniprotkb:D6VV20 psi-mi:pfka2_yeast(display_long)|uniprotkb:PFK2(gene name)|psi-mi:PFK2(display_short)|uniprotkb:YMR205C(locus name)|uniprotkb:YM8325.06C(orf name)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:ATP-dependent 6-phosphofructokinase(gene name synonym) psi-mi:pfka1_yeast(display_long)|uniprotkb:PFK1(gene name)|psi-mi:PFK1(display_short)|uniprotkb:YGR240C(locus name)|uniprotkb:G8599(orf name)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:ATP-dependent 6-phosphofructokinase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319184|imex:IM-26944-201 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR205C(gene)|ensemblfungi:YMR205C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005945"(6-phosphofructokinase complex)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016208"(AMP binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070072"(vacuolar proton-transporting V-type ATPase complex assembly)|go:"GO:0070095"(fructose-6-phosphate binding)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000023(Phosphofructokinase)|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR022953|interpro:IPR029068|interpro:IPR035966|rcsb pdb:3O8O|reactome:R-SCE-6798695|reactome:R-SCE-70171|refseq:NP_013932.1|sgd:S000004818|mint:P16862|dip:DIP-2619N|ensemblgenomes:YMR205C(identity) refseq:NP_011756.1|sgd:S000003472|ensemblfungi:YGR240C(gene)|ensemblfungi:YGR240C_mRNA(transcript)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005945"(6-phosphofructokinase complex)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0016208"(AMP binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070095"(fructose-6-phosphate binding)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000023(Phosphofructokinase)|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR022953|interpro:IPR035966|interpro:IPR040712|rcsb pdb:3O8O|reactome:R-SCE-6798695|reactome:R-SCE-70171|mint:P16861|dip:DIP-1505N|ensemblgenomes:YGR240C(identity) - crc64:82CE6402CEDBBCB2 crc64:995B3DF7C7781B29 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:PurR+sy8cBMAoGxl0dMMcxuz8wI559292 rogid:mqqXE8Cvcp019pDQsU01zBYUsCc559292 rigid:YztK6VVRt09yLhYY9LvzXnu5ov0 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q00582 uniprotkb:P53290 intact:EBI-7954|uniprotkb:D6W0G3|ensemblfungi:YML121W intact:EBI-7962|uniprotkb:D6VUU7|ensemblfungi:YGR163W psi-mi:gtr1_yeast(display_long)|uniprotkb:YM7056.05(orf name)|uniprotkb:YML121W(locus name)|uniprotkb:GTR1(gene name)|psi-mi:GTR1(display_short) psi-mi:gtr2_yeast(display_long)|uniprotkb:YGR163W(locus name)|uniprotkb:GTR2(gene name)|psi-mi:GTR2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319172|imex:IM-26944-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013585.1|sgd:S000004590|mint:Q00582|dip:DIP-1358N|ensemblfungi:YML121W(gene)|ensemblfungi:YML121W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006348"|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990131"(Gtr1-Gtr2 GTPase complex)|interpro:IPR006762(Gtr1/RagA G protein)|interpro:IPR027417|interpro:IPR039397|rcsb pdb:3R7W|rcsb pdb:4ARZ|rcsb pdb:6JWP|reactome:R-SCE-165159|reactome:R-SCE-9639288|ensemblgenomes:YML121W(identity) sgd:S000003395|refseq:NP_011679.3|mint:P53290|dip:DIP-4521N|ensemblfungi:YGR163W(gene)|ensemblfungi:YGR163W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000785"(chromatin)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990131"(Gtr1-Gtr2 GTPase complex)|interpro:IPR006762(Gtr1/RagA G protein)|interpro:IPR027417|interpro:IPR039400|rcsb pdb:3R7W|rcsb pdb:4ARZ|rcsb pdb:6JWP|reactome:R-SCE-165159|reactome:R-SCE-9639288|ensemblgenomes:YGR163W(identity) - crc64:B79CE7FE7AD2FDBE crc64:0A0D16C81F73184D figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:5LJU5zMF4NDDY9Bmndu0Q+JIm54559292 rogid:+b9bPvzin/YUc5fOZZVCcFu/GEM559292 rigid:LVXxv4cLIEbNVWFQnXnwzP/YAus false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41948 uniprotkb:P40260 intact:EBI-10721|ensemblfungi:YNL142W|uniprotkb:D6W140 intact:EBI-10714|ensemblfungi:YGR121C|uniprotkb:D6VUQ2 psi-mi:mep2_yeast(display_long)|uniprotkb:MEP2(gene name)|psi-mi:MEP2(display_short)|uniprotkb:YNL142W(locus name)|uniprotkb:N1207(orf name)|uniprotkb:N1820(orf name)|uniprotkb:AMT2(gene name synonym) psi-mi:mep1_yeast(display_long)|uniprotkb:MEP1(gene name)|psi-mi:MEP1(display_short)|uniprotkb:YGR121C(locus name)|uniprotkb:G6331(orf name)|uniprotkb:AMT1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319160|imex:IM-26944-635 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL142W(gene)|ensemblfungi:YNL142W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|go:"GO:1900430"(positive regulation of filamentous growth of a population of unicellular organisms)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|rcsb pdb:5AEX|refseq:NP_014257.1|sgd:S000005086|dip:DIP-4340N|ensemblgenomes:YNL142W(identity) ensemblfungi:YGR121C(gene)|ensemblfungi:YGR121C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|sgd:S000003353|refseq:NP_011636.3|mint:P40260|dip:DIP-5530N|ensemblgenomes:YGR121C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:3UqhhEzAfYLfblLgaIyu9opa9RI559292 rogid:VnoBl5jhQD24N0SbCLv68HCwl1U559292 rigid:NjHR+x1gFffiXta3L9g64SVe3lg false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06103 uniprotkb:P53235 intact:EBI-8973|ensemblfungi:YOR361C|uniprotkb:D6W356 intact:EBI-23172|uniprotkb:D6VUI9|uniprotkb:Q45U32|ensemblfungi:YGR054W psi-mi:eif3b_yeast(display_long)|uniprotkb:YOR361C(locus name)|uniprotkb:PRT1(gene name)|psi-mi:PRT1(display_short)|uniprotkb:CDC63(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 90 kDa subunit(gene name synonym)|uniprotkb:Translation initiation factor eIF3 p90 subunit(gene name synonym)|uniprotkb:Cell cycle regulation and translation initiation protein(gene name synonym) psi-mi:eif2a_yeast(display_long)|uniprotkb:YGR054W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319148|imex:IM-26944-289 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR361C(gene)|ensemblfungi:YOR361C_mRNA(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043614"(multi-eIF complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR011400(Translation initiation factor eIF-3b)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR034363|interpro:IPR035979|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:3NS5|rcsb pdb:3NS6|rcsb pdb:3ZWL|rcsb pdb:4U1E|rcsb pdb:4U1F|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6ZCE|rcsb pdb:6ZU9|reactome:R-SCE-156827|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|refseq:NP_015006.3|sgd:S000005888|mint:P06103|dip:DIP-2519N|ensemblgenomes:YOR361C(identity) sgd:S000003286|refseq:NP_011568.3|dip:DIP-5518N|mint:P53235|ensemblfungi:YGR054W(gene)|ensemblfungi:YGR054W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0006413"(translational initiation)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|interpro:IPR011387(Translation initiation factor eIF-2A)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|ensemblgenomes:YGR054W(identity) - crc64:F5E4E783408EE948 crc64:F3C2E78504D83418 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:KeOY80g2TW3axiQNc1iJhsqEUPM559292 rogid:x8zDCH5W5GusC7qYd0mDATXhGVI559292 rigid:oiKVP+X6b1csKg94+npxD4lo38Q false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14359 uniprotkb:P56508 intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C intact:EBI-22135|uniprotkb:D6VTE7|ensemblfungi:YDR525W-A psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:sna2_yeast(display_long)|uniprotkb:YDR525BW(orf name)|uniprotkb:YDR525W-A(locus name)|uniprotkb:SNA2(gene name)|psi-mi:SNA2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319136|imex:IM-26944-367 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD|ensemblgenomes:YJL151C(identity) refseq:NP_010814.1|sgd:S000007236|interpro:IPR000612(Protein of unknown function UPF0057)|ensemblfungi:YDR525W-A(gene)|ensemblfungi:YDR525W-A_mRNA(transcript)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|ensemblgenomes:YDR525W-A(identity) - crc64:DBA26AF5B769C02A - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 rogid:zqjXp3iXSEELPlEPJCNgQgsCr+o559292 rigid:ZAcX49Pzwa7p12g3YyDqWCWtYwI false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34166 uniprotkb:P34165 intact:EBI-10821|ensemblfungi:YNL145W|uniprotkb:D6W138 intact:EBI-10814|ensemblfungi:YDR461W|uniprotkb:D6VT85 psi-mi:mfa2_yeast(display_long)|uniprotkb:N1204(orf name)|uniprotkb:N1787(orf name)|uniprotkb:YNL145W(locus name)|uniprotkb:MFA2(gene name)|psi-mi:MFA2(display_short) psi-mi:mfa1_yeast(display_long)|uniprotkb:D8035.5(orf name)|uniprotkb:YDR461W(locus name)|uniprotkb:MFA1(gene name)|psi-mi:MFA1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319124|imex:IM-26944-105 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL145W(gene)|ensemblfungi:YNL145W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0000772"(mating pheromone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006113"(fermentation)|interpro:IPR035296|go:"GO:0005886"(plasma membrane)|sgd:S000005089|refseq:NP_014254.1|dip:DIP-2140N|ensemblgenomes:YNL145W(identity) ensemblfungi:YDR461W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0000772"(mating pheromone activity)|ensemblfungi:YDR461W(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|interpro:IPR035296|sgd:S000002869|refseq:NP_010749.3|dip:DIP-4646N|ensemblgenomes:YDR461W(identity) - - crc64:03E051D7D6C2522F figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:SopqK/s1f2PoCn7RWS8fsSZNZ1k559292 rogid:sVc3qoMFihhQ0zG3wEDg9eyMc9g559292 rigid:oIagLPfkIIWUIMKJF24lqsWInMU false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47165 uniprotkb:Q04178 intact:EBI-25682|uniprotkb:D6VWV1|ensemblfungi:YJR133W intact:EBI-29727|uniprotkb:D6VT32|ensemblfungi:YDR399W psi-mi:xpt1_yeast(display_long)|uniprotkb:XPT1(gene name)|psi-mi:XPT1(display_short)|uniprotkb:J2118(orf name)|uniprotkb:YJR133W(locus name) psi-mi:hprt_yeast(display_long)|uniprotkb:BRA6(gene name synonym)|uniprotkb:YDR399W(locus name)|uniprotkb:Bypass of repression by adenine protein 6(gene name synonym)|uniprotkb:HPT1(gene name)|psi-mi:HPT1(display_short)|uniprotkb:D9509.18(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319112|imex:IM-26944-365 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012667.1|sgd:S000003894|mint:P47165|dip:DIP-1576N|ensemblfungi:YJR133W(gene)|ensemblfungi:YJR133W_mRNA(transcript)|go:"GO:0000310"(xanthine phosphoribosyltransferase activity)|go:"GO:0004422"(hypoxanthine phosphoribosyltransferase activity)|go:"GO:0004615"(phosphomannomutase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0032263"(GMP salvage)|go:"GO:0032264"(IMP salvage)|go:"GO:0032265"(XMP salvage)|go:"GO:0046100"(hypoxanthine metabolic process)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR029057|ensemblgenomes:YJR133W(identity) sgd:S000002807|refseq:NP_010687.3|dip:DIP-4318N|ensemblfungi:YDR399W(gene)|ensemblfungi:YDR399W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0004422"(hypoxanthine phosphoribosyltransferase activity)|go:"GO:0004615"(phosphomannomutase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0032263"(GMP salvage)|go:"GO:0032264"(IMP salvage)|go:"GO:0032265"(XMP salvage)|go:"GO:0046100"(hypoxanthine metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0052657"(guanine phosphoribosyltransferase activity)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR029057|rcsb pdb:2JKY|rcsb pdb:2JKZ|rcsb pdb:2XBU|ensemblgenomes:YDR399W(identity) - - crc64:0D18A02BAF8F5390 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:hjdGDsZ62F5m8o7QAcZMoVVXWVc559292 rogid:5WavMdg6hpLH/ODtat1kRkPknSk559292 rigid:N7uZxyBKzf1ELQI34CM5t4XbCqU false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P05319 uniprotkb:P02400 intact:EBI-15456|uniprotkb:D6W227|ensemblfungi:YOL039W intact:EBI-15464|uniprotkb:D6VT16|ensemblfungi:YDR382W psi-mi:rla2_yeast(display_long)|uniprotkb:RPP2A(gene name)|psi-mi:RPP2A(display_short)|uniprotkb:L12EIB(gene name synonym)|uniprotkb:RPA2(gene name synonym)|uniprotkb:RPL44(gene name synonym)|uniprotkb:RPLA2(gene name synonym)|uniprotkb:L12eIB(gene name synonym)|uniprotkb:YP2alpha(gene name synonym)|uniprotkb:L44(gene name synonym)|uniprotkb:YOL039W(locus name)|uniprotkb:Large ribosomal subunit protein P2-A(gene name synonym) psi-mi:rla4_yeast(display_long)|uniprotkb:RPP2B(gene name)|psi-mi:RPP2B(display_short)|uniprotkb:L12EIA(gene name synonym)|uniprotkb:RPL45(gene name synonym)|uniprotkb:RPLA4(gene name synonym)|uniprotkb:L12eIA(gene name synonym)|uniprotkb:YP2beta(gene name synonym)|uniprotkb:L45(gene name synonym)|uniprotkb:YL44C(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:YDR382W(locus name)|uniprotkb:Large ribosomal subunit protein P2-B(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319100|imex:IM-26944-633 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014603.1|sgd:S000005399|ensemblfungi:YOL039W(gene)|ensemblfungi:YOL039W_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002182"(cytoplasmic translational elongation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030295"(protein kinase activator activity)|interpro:IPR027534|interpro:IPR038716|interpro:IPR044076|rcsb pdb:4V6I|dip:DIP-2506N|ensemblgenomes:YOL039W(identity) sgd:S000002790|reactome:R-SCE-156827|reactome:R-SCE-1799339|reactome:R-SCE-72689|reactome:R-SCE-72706|reactome:R-SCE-975956|reactome:R-SCE-975957|refseq:NP_010670.3|ensemblfungi:YDR382W(gene)|ensemblfungi:YDR382W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002182"(cytoplasmic translational elongation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0045860"(positive regulation of protein kinase activity)|interpro:IPR027534|interpro:IPR038716|interpro:IPR044076|rcsb pdb:3N2D|rcsb pdb:3N3X|dip:DIP-580N|ensemblgenomes:YDR382W(identity) - - crc64:EC45406CB5F199F4 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:bvmZbhGsNuMJEdAv9ac1wD6Y+Rs559292 rogid:dvY8zJb/i5nIRnNekgTQdY9Novs559292 rigid:UhwAY+TyMb9nYVug9e2Fm27cgKw false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53834 uniprotkb:Q12449 intact:EBI-28288|uniprotkb:D6W0R3|ensemblfungi:YNL281W intact:EBI-37072|uniprotkb:Q02565|uniprotkb:Q7LIE3|uniprotkb:D6VSJ8|ensemblfungi:YDR214W psi-mi:hch1_yeast(display_long)|uniprotkb:HCH1(gene name)|psi-mi:HCH1(display_short)|uniprotkb:YNL281W(locus name)|uniprotkb:N0589(orf name)|uniprotkb:High-copy Hsp90 suppressor protein 1(gene name synonym) psi-mi:aha1_yeast(display_long)|uniprotkb:AHA1(gene name)|psi-mi:AHA1(display_short)|uniprotkb:YDR214W(locus name)|uniprotkb:YD8142.16(orf name)|uniprotkb:YD8142B.06(orf name)|uniprotkb:Activator of Hsp90 ATPase protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319088|imex:IM-26944-631 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014118.1|sgd:S000005225|dip:DIP-4395N|mint:P53834|ensemblfungi:YNL281W(gene)|ensemblfungi:YNL281W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|interpro:IPR015310(Activator of Hsp90 ATPase, N-terminal)|interpro:IPR036338|interpro:IPR039981|ensemblgenomes:YNL281W(identity) sgd:S000002622|refseq:NP_010500.3|mint:Q12449|dip:DIP-1831N|ensemblfungi:YDR214W(gene)|ensemblfungi:YDR214W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|interpro:IPR013538(Activator of Hsp90 ATPase homologue 1-like)|interpro:IPR015310(Activator of Hsp90 ATPase, N-terminal)|interpro:IPR023393|interpro:IPR036338|interpro:IPR039981|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:6XLB|rcsb pdb:6XLD|rcsb pdb:6XLE|rcsb pdb:6XLF|rcsb pdb:6XLG|rcsb pdb:6XLH|ensemblgenomes:YDR214W(identity) - crc64:DAD84DBF9BF5DC9F crc64:06DF6B40EB5050BE figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:f1gS31qqt1jGRycD4GVoWw043Cs559292 rogid:jCVFPwj0+auPVB/BJ/OwlMSBWUM559292 rigid:nqoKmaO6wN6zDqcL88DH8xdb/LY false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O13516 uniprotkb:P05755 intact:EBI-16176|ensemblfungi:YPL081W|uniprotkb:D6W3T6 intact:EBI-16181|ensemblfungi:YBR189W|uniprotkb:D6VQI4 psi-mi:rs9a_yeast(display_long)|uniprotkb:RPS9A(gene name)|psi-mi:RPS9A(display_short)|uniprotkb:RPS13A(gene name synonym)|uniprotkb:YS11A(gene name synonym)|uniprotkb:YPL081W(locus name)|uniprotkb:S13(gene name synonym)|uniprotkb:YS11(gene name synonym)|uniprotkb:RP21(gene name synonym)|uniprotkb:YP28(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS4-A(gene name synonym) psi-mi:rs9b_yeast(display_long)|uniprotkb:RPS9B(gene name)|psi-mi:RPS9B(display_short)|uniprotkb:RPS13B(gene name synonym)|uniprotkb:SUP46(gene name synonym)|uniprotkb:YBR189W(locus name)|uniprotkb:YBR1317(orf name)|uniprotkb:S13(gene name synonym)|uniprotkb:YS11(gene name synonym)|uniprotkb:RP21(gene name synonym)|uniprotkb:YP28(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS4-B(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319280|imex:IM-26944-445 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL081W(gene)|ensemblfungi:YPL081W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0019843"(rRNA binding)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0045903"(positive regulation of translational fidelity)|rcsb pdb:1K5X|rcsb pdb:3J6X|rcsb pdb:3J6Y|rcsb pdb:3J78|rcsb pdb:4U3M|rcsb pdb:4U3N|rcsb pdb:4U3U|rcsb pdb:4U4N|rcsb pdb:4U4O|rcsb pdb:4U4Q|rcsb pdb:4U4R|rcsb pdb:4U4U|rcsb pdb:4U4Y|rcsb pdb:4U4Z|rcsb pdb:4U50|rcsb pdb:4U51|rcsb pdb:4U52|rcsb pdb:4U53|rcsb pdb:3J77|rcsb pdb:4U55|rcsb pdb:4U56|rcsb pdb:4U6F|rcsb pdb:6Z6K|rcsb pdb:6ZCE|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:6ZQG|rcsb pdb:6ZU9|rcsb pdb:6ZVI|rcsb pdb:7A1G|rcsb pdb:7AJT|rcsb pdb:7AJU|rcsb pdb:7B7D|rcsb pdb:7NRC|rcsb pdb:7NRD|rcsb pdb:4V6I|rcsb pdb:4V7R|rcsb pdb:4V88|rcsb pdb:4V8Y|rcsb pdb:4V8Z|rcsb pdb:4V92|rcsb pdb:5DAT|rcsb pdb:5DC3|rcsb pdb:5DGE|rcsb pdb:5DGF|rcsb pdb:5DGV|rcsb pdb:5FCI|rcsb pdb:5FCJ|rcsb pdb:5I4L|rcsb pdb:5JPQ|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:5LL6|rcsb pdb:4V4B|rcsb pdb:5LYB|rcsb pdb:5M1J|rcsb pdb:5MC6|rcsb pdb:5MEI|rcsb pdb:5NDG|rcsb pdb:5NDV|rcsb pdb:5NDW|rcsb pdb:5OBM|rcsb pdb:5ON6|rcsb pdb:5TBW|rcsb pdb:5TGA|rcsb pdb:5TGM|rcsb pdb:5TZS|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6EML|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6Q8Y|rcsb pdb:6RBD|rcsb pdb:6RBE|rcsb pdb:6S47|rcsb pdb:6SNT|rcsb pdb:6SV4|rcsb pdb:6FAI|rcsb pdb:6T4Q|rcsb pdb:6T7I|rcsb pdb:6GQ1|rcsb pdb:6T7T|rcsb pdb:6T83|rcsb pdb:6GQB|rcsb pdb:6GQV|rcsb pdb:6HHQ|rcsb pdb:6I7O|rcsb pdb:6KE6|rcsb pdb:6TB3|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6TNU|rcsb pdb:6WDR|rcsb pdb:6XIQ|rcsb pdb:6XIR|rcsb pdb:6Y7C|rcsb pdb:6Z6J|refseq:NP_015244.1|sgd:S000006002|interpro:IPR022801|interpro:IPR005710(Ribosomal protein S4/S9, eukaryotic/archaeal)|interpro:IPR001912(Ribosomal protein S4)|interpro:IPR018079|interpro:IPR002942(RNA-binding S4)|mint:O13516|interpro:IPR036986|ensemblgenomes:YPL081W(identity) ensemblfungi:YBR189W(gene)|rcsb pdb:6WOO|ensemblfungi:YBR189W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|reactome:R-SCE-156827|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0019843"(rRNA binding)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0045903"(positive regulation of translational fidelity)|reactome:R-SCE-1799339|reactome:R-SCE-6791226|reactome:R-SCE-72649|reactome:R-SCE-72689|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72706|reactome:R-SCE-975956|reactome:R-SCE-975957|sgd:S000000393|interpro:IPR022801|interpro:IPR005710(Ribosomal protein S4/S9, eukaryotic/archaeal)|interpro:IPR001912(Ribosomal protein S4)|interpro:IPR018079|interpro:IPR002942(RNA-binding S4)|refseq:NP_009748.3|mint:P05755|interpro:IPR036986|ensemblgenomes:YBR189W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:vAdW2QQWeep7eysGfwdrph+099Q559292 rogid:VVaUiekAztpO7wESU7DqtLDIb7E559292 rigid:T9aIfgy0eymGhEsM5lv+yF91TgU false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34761 uniprotkb:Q07655 intact:EBI-20537|uniprotkb:D6W0Z0|ensemblfungi:YNL197C intact:EBI-31312|uniprotkb:D6VRD1|ensemblfungi:YDL224C psi-mi:whi3_yeast(display_long)|uniprotkb:WHI3(gene name)|psi-mi:WHI3(display_short)|uniprotkb:N1382(orf name)|uniprotkb:YNL197C(locus name) psi-mi:whi4_yeast(display_long)|uniprotkb:WHI4(gene name)|psi-mi:WHI4(display_short)|uniprotkb:D0839(orf name)|uniprotkb:YDL224C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319388|imex:IM-26944-539 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014202.1|sgd:S000005141|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|ensemblfungi:YNL197C(gene)|ensemblfungi:YNL197C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0032106"(positive regulation of response to extracellular stimulus)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0061013"(regulation of mRNA catabolic process)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071554"(cell wall organization or biogenesis)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:P34761|ensemblgenomes:YNL197C(identity) refseq:NP_010057.1|sgd:S000002383|dip:DIP-4321N|mint:Q07655|ensemblfungi:YDL224C(gene)|ensemblfungi:YDL224C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008361"(regulation of cell size)|go:"GO:0061157"(mRNA destabilization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|ensemblgenomes:YDL224C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:Xpn0uJiaylcupy9qYDLa0V++z6A559292 rogid:zPUzt32TQkMfrkafLvfsgHhZbYA559292 rigid:Mna4GPDmxgppt18JTgCWcZKWvYc false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04947 uniprotkb:Q12443 intact:EBI-38020|uniprotkb:D6VSL4|ensemblfungi:YDR233C intact:EBI-32591|uniprotkb:D6VRF0|ensemblfungi:YDL204W psi-mi:rtn1_yeast(display_long)|uniprotkb:RTN1(gene name)|psi-mi:RTN1(display_short)|uniprotkb:YDR233C(locus name) psi-mi:rtn2_yeast(display_long)|uniprotkb:RTN2(gene name)|psi-mi:RTN2(display_short)|uniprotkb:D1062(orf name)|uniprotkb:YDL204W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319376|imex:IM-26944-115 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002641|refseq:NP_010519.3|dip:DIP-4090N|mint:Q04947|ensemblfungi:YDR233C(gene)|ensemblfungi:YDR233C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032581"(ER-dependent peroxisome organization)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0071458"(integral component of cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0071788"(endoplasmic reticulum tubular network maintenance)|go:"GO:0071944"(cell periphery)|interpro:IPR003388(Reticulon)|ensemblgenomes:YDR233C(identity) refseq:NP_010077.1|sgd:S000002363|dip:DIP-4231N|mint:Q12443|ensemblfungi:YDL204W(gene)|ensemblfungi:YDL204W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032581"(ER-dependent peroxisome organization)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0071788"(endoplasmic reticulum tubular network maintenance)|go:"GO:0071944"(cell periphery)|interpro:IPR003388(Reticulon)|ensemblgenomes:YDL204W(identity) - crc64:245575E65D3C2193 crc64:E937E2B77759DFF5 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:EEXsl6gyB0GVuwAEwN1AAOF8h1E559292 rogid:jF49AeaM5t7a5TBw3/+tJ7H251g559292 rigid:Ln4rdPGXf97soYcHhQQU5ulx6Cg false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11076 uniprotkb:P19146 intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W intact:EBI-2820|uniprotkb:A2TBP3|uniprotkb:D6VRL1|ensemblfungi:YDL137W psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:arf2_yeast(display_long)|uniprotkb:ARF2(gene name)|psi-mi:ARF2(display_short)|uniprotkb:D2165(orf name)|uniprotkb:YDL137W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319364|imex:IM-26944-537 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438|ensemblgenomes:YDL192W(identity) refseq:NP_010144.1|sgd:S000002296|dip:DIP-2215N|mint:P19146|ensemblfungi:YDL137W(gene)|ensemblfungi:YDL137W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:1MR3|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438|ensemblgenomes:YDL137W(identity) - crc64:796859026AC63CC0 crc64:7E43FF792E8D64E8 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 rogid:I4V9cXleaZ2sAE2DXGKt8zpAPzw559292 rigid:AT1OwijMU0sHBxGzKEBnmNTCjC8 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48813 uniprotkb:P25376 intact:EBI-7758|uniprotkb:D6VTD0|ensemblfungi:YDR508C intact:EBI-2357|uniprotkb:D6VQZ1|ensemblfungi:YCL025C psi-mi:gnp1_yeast(display_long)|uniprotkb:GNP1(gene name)|psi-mi:GNP1(display_short)|uniprotkb:D9719.14(orf name)|uniprotkb:YDR508C(locus name) psi-mi:agp1_yeast(display_long)|uniprotkb:AGP1(gene name)|psi-mi:AGP1(display_short)|uniprotkb:YCL025C(locus name)|uniprotkb:YCL25C(orf name)|uniprotkb:Asparagine/glutamine permease(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319304|imex:IM-26944-639 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010796.1|sgd:S000002916|dip:DIP-1616N|ensemblfungi:YDR508C(gene)|ensemblfungi:YDR508C_mRNA(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015193"(L-proline transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:0098718"(serine import across plasma membrane)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region)|ensemblgenomes:YDR508C(identity) refseq:NP_009905.3|sgd:S000000530|dip:DIP-4973N|mint:P25376|ensemblfungi:YCL025C(gene)|ensemblfungi:YCL025C_mRNA(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015192"(L-phenylalanine transmembrane transporter activity)|go:"GO:0015193"(L-proline transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0098718"(serine import across plasma membrane)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region)|ensemblgenomes:YCL025C(identity) - crc64:9A5ED9CF7C1DD977 crc64:8E19A836C2F6C50F figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:ViyFFdYNUSkZx7fowfIivmwwM/k559292 rogid:bB5pBnaoMUTwxlz8v5MAjCWc4Mg559292 rigid:EYyMuL9YQiZtkLRy0tTIYOQL9wk false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03790 uniprotkb:Q05166 intact:EBI-27321|uniprotkb:D6VZX4|ensemblfungi:YMR153W intact:EBI-3035|uniprotkb:Q12456|uniprotkb:E9P903|uniprotkb:D6VRR0|ensemblfungi:YDL088C psi-mi:nup53_yeast(display_long)|uniprotkb:Nuclear pore protein NUP53(gene name synonym)|uniprotkb:NUP53(gene name)|psi-mi:NUP53(display_short)|uniprotkb:YMR153W(locus name)|uniprotkb:YM8520.02(orf name) psi-mi:nup59_yeast(display_long)|uniprotkb:ASM4(gene name)|psi-mi:ASM4(display_short)|uniprotkb:Nuclear pore protein NUP59(gene name synonym)|uniprotkb:NUP59(gene name synonym)|uniprotkb:D2420(orf name)|uniprotkb:YDL088C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319340|imex:IM-26944-643 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013873.1|sgd:S000004762|dip:DIP-1467N|ensemblfungi:YMR153W(gene)|ensemblfungi:YMR153W_mRNA(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|go:"GO:0060188"(regulation of protein desumoylation)|go:"GO:0072417"(response to spindle checkpoint signaling)|interpro:IPR007846(MPPN)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017389(Nucleoporin, NUP53)|interpro:IPR035979|rcsb pdb:3W3Y|rcsb pdb:5UAZ|ensemblgenomes:YMR153W(identity) refseq:NP_010195.1|sgd:S000002246|dip:DIP-1466N|mint:Q05166|ensemblfungi:YDL088C(gene)|ensemblfungi:YDL088C_mRNA(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007049"(cell cycle)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0051301"(cell division)|interpro:IPR007846(MPPN)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017389(Nucleoporin, NUP53)|interpro:IPR035979|ensemblgenomes:YDL088C(identity) - crc64:2ECE0C561D27E523 - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:csq2oRFswkgY2JkT+dmz/L7Zpfk559292 rogid:t8/JWDKB0Spe2P8qdZnKs/RB3SY559292 rigid:173SyJisU911RF7Xnxlhei7EsIg false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39540 uniprotkb:P25358 intact:EBI-7745012|ensemblfungi:YJL196C|uniprotkb:D6VVZ6|intact:MINT-1357650 intact:EBI-6415|uniprotkb:D6VR44|ensemblfungi:YCR034W psi-mi:elo1_yeast(display_long)|uniprotkb:ELO1(gene name)|psi-mi:ELO1(display_short)|uniprotkb:3-keto acyl-CoA synthase ELO1(gene name synonym)|uniprotkb:Very-long-chain 3-oxoacyl-CoA synthase 1(gene name synonym)|uniprotkb:J0343(orf name)|uniprotkb:YJL196C(locus name) psi-mi:elo2_yeast(display_long)|uniprotkb:ELO2(gene name)|psi-mi:ELO2(display_short)|uniprotkb:3-keto acyl-CoA synthase ELO2(gene name synonym)|uniprotkb:FEN1(gene name synonym)|uniprotkb:Fenpropimorph resistance protein 1(gene name synonym)|uniprotkb:GNS1(gene name synonym)|uniprotkb:Glucan synthesis protein 1(gene name synonym)|uniprotkb:VBM2(gene name synonym)|uniprotkb:Very-long-chain 3-oxoacyl-CoA synthase 2(gene name synonym)|uniprotkb:v-SNARE bypass mutant gene 2 protein(gene name synonym)|uniprotkb:YCR34W(orf name)|uniprotkb:YCR521(orf name)|uniprotkb:YCR034W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319328|imex:IM-26944-203 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YJL196C(gene)|ensemblfungi:YJL196C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0009922"(fatty acid elongase activity)|go:"GO:0019367"(fatty acid elongation, saturated fatty acid)|go:"GO:0019368"(fatty acid elongation, unsaturated fatty acid)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034625"(fatty acid elongation, monounsaturated fatty acid)|go:"GO:0034626"(fatty acid elongation, polyunsaturated fatty acid)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0102336"(3-oxo-arachidoyl-CoA synthase activity)|go:"GO:0102337"(3-oxo-cerotoyl-CoA synthase activity)|go:"GO:0102338"(3-oxo-lignoceronyl-CoA synthase activity)|go:"GO:0102756"(very-long-chain 3-ketoacyl-CoA synthase activity)|interpro:IPR002076(GNS1/SUR4 membrane protein)|interpro:IPR030457|sgd:S000003732|refseq:NP_012339.1|dip:DIP-8755N|ensemblgenomes:YJL196C(identity) refseq:NP_009963.1|sgd:S000000630|dip:DIP-4176N|ensemblfungi:YCR034W(gene)|ensemblfungi:YCR034W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0009922"(fatty acid elongase activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019367"(fatty acid elongation, saturated fatty acid)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030497"(fatty acid elongation)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0034625"(fatty acid elongation, monounsaturated fatty acid)|go:"GO:0034626"(fatty acid elongation, polyunsaturated fatty acid)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0102336"(3-oxo-arachidoyl-CoA synthase activity)|go:"GO:0102337"(3-oxo-cerotoyl-CoA synthase activity)|go:"GO:0102338"(3-oxo-lignoceronyl-CoA synthase activity)|go:"GO:0102756"(very-long-chain 3-ketoacyl-CoA synthase activity)|interpro:IPR002076(GNS1/SUR4 membrane protein)|interpro:IPR030457|ensemblgenomes:YCR034W(identity) - comment:mint|function:"May be a membrane bound enzyme involved in the highly specific elongation of saturated 14-carbon fatty acids (14:0) to 16-carbon species (16:0)" - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:ZTgAn3eBkLQSYokr0UxYXfg1rqs559292 rogid:jsOgGXbO4Dc/VC/WL/k4r/S9Acs559292 rigid:WPAP+iLO7hYBhKGKqk+BE0DgPk8 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12034 uniprotkb:P25567 intact:EBI-17335|uniprotkb:D6VTD6|uniprotkb:E9P8Z6|ensemblfungi:YDR515W intact:EBI-18084|uniprotkb:D6VQX8|ensemblfungi:YCL037C psi-mi:slf1_yeast(display_long)|uniprotkb:D9719.20(orf name)|uniprotkb:YDR515W(locus name)|uniprotkb:SLF1(gene name)|psi-mi:SLF1(display_short) psi-mi:sro9_yeast(display_long)|uniprotkb:SRO9(gene name)|psi-mi:SRO9(display_short)|uniprotkb:YCL037C(locus name)|uniprotkb:YCL37C(orf name)|uniprotkb:Suppressor of RHO3 protein 9(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319316|imex:IM-26944-641 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010803.3|sgd:S000002923|ensemblfungi:YDR515W(gene)|ensemblfungi:YDR515W_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006417"(regulation of translation)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0010494"(cytoplasmic stress granule)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390|dip:DIP-2938N|mint:Q12034|ensemblgenomes:YDR515W(identity) refseq:NP_009893.2|sgd:S000000542|ensemblfungi:YCL037C(gene)|ensemblfungi:YCL037C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005844"(polysome)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390|dip:DIP-6638N|mint:P25567|ensemblgenomes:YCL037C(identity) - - crc64:B1B720D40C7B9914 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:XBjQud6beJKzvJeWksARACuczoY559292 rogid:CouwiBsK7S3Tm6CoBsu3LdWfelg559292 rigid:3q/ohIcjcL4C6FzCotgwNfPnF4k false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P01098 uniprotkb:P01097 intact:EBI-8080380|intact:MINT-2785764|uniprotkb:D6VRL9|ensemblfungi:YDL130W-A intact:EBI-8874|ensemblfungi:YDL181W|uniprotkb:D6VRH1 psi-mi:stf1_yeast(display_long)|uniprotkb:STF1(gene name)|psi-mi:STF1(display_short)|uniprotkb:AIS2(gene name synonym)|uniprotkb:ATP synthase F1 subunit epsilon(gene name synonym)|uniprotkb:YDL130BW(orf name)|uniprotkb:YDL130W-A(locus name) psi-mi:atif_yeast(display_long)|uniprotkb:INH1(gene name)|psi-mi:INH1(display_short)|uniprotkb:ATP synthase F1 subunit epsilon(gene name synonym)|uniprotkb:D1305(orf name)|uniprotkb:YDL181W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319352|imex:IM-26944-113 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010152.1|mint:P01098|interpro:IPR007648(Mitochondrial ATPase inhibitor, IATP)|sgd:S000007232|ensemblfungi:YDL130W-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051117"(ATPase binding)|ensemblfungi:YDL130W-A(gene)|ensemblgenomes:YDL130W-A(identity) ensemblfungi:YDL181W(gene)|ensemblfungi:YDL181W_mRNA(transcript)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0042030"(ATPase inhibitor activity)|interpro:IPR007648(Mitochondrial ATPase inhibitor, IATP)|rcsb pdb:3ZIA|refseq:NP_010100.1|sgd:S000002340|mint:P01097|dip:DIP-2985N|ensemblgenomes:YDL181W(identity) - comment:mint|function:This is 1 of 2 proteins that can stabilize the ATPase-inhibitor complex, which normally dissociates when externally added ATP has been consumed crc64:E1AF73A47F63CE58 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:YxrqEhb1G8Ln3oLqBYbVRmFM7E4559292 rogid:3wsu4TOLAZdm97Kfhla8l4UKFEk559292 rigid:LIGNnzVvA74xi0UM5JQwIougdM8 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36122 uniprotkb:P40955 intact:EBI-26374|uniprotkb:D6VX92|ensemblfungi:YKR027W intact:EBI-4649|uniprotkb:D6VW85|ensemblfungi:YJL099W psi-mi:bch2_yeast(display_long)|uniprotkb:YKR027W(locus name)|uniprotkb:BUD7 and CHS6 homolog 2(gene name synonym)|uniprotkb:BCH2(gene name)|psi-mi:BCH2(display_short)|uniprotkb:FMP50(gene name synonym) psi-mi:chs6_yeast(display_long)|uniprotkb:CHS6(gene name)|psi-mi:CHS6(display_short)|uniprotkb:CSD3(gene name synonym)|uniprotkb:YJL099W(locus name)|uniprotkb:J0838(orf name)|uniprotkb:Protein CSD3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319736|imex:IM-26944-211 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001735|interpro:IPR015374(Chs5p-Arf1p binding)|interpro:IPR011990(Tetratricopeptide-like helical)|refseq:NP_012952.3|mint:P36122|ensemblfungi:YKR027W(gene)|ensemblfungi:YKR027W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0034044"(exomer complex)|go:"GO:0034221"(fungal-type cell wall chitin biosynthetic process)|ensemblgenomes:YKR027W(identity) refseq:NP_012436.1|sgd:S000003635|dip:DIP-5682N|ensemblfungi:YJL099W(gene)|ensemblfungi:YJL099W_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0034044"(exomer complex)|go:"GO:0034221"(fungal-type cell wall chitin biosynthetic process)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015374(Chs5p-Arf1p binding)|rcsb pdb:4WJW|rcsb pdb:4YG8|ensemblgenomes:YJL099W(identity) - - crc64:BD92DADA3D5396BC figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:qslkZkP7uV5VCA3xouTfbs5IW9Q559292 rogid:Y8OojYpAni4fbeoZN5eaJaBGISM559292 rigid:pmsYYTHE9AvodqCuIIkCkvp1yn0 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32660 uniprotkb:Q12675 intact:EBI-3121|uniprotkb:D3DM74|ensemblfungi:YER166W intact:EBI-3114|uniprotkb:D6VS80|ensemblfungi:YDR093W psi-mi:atc5_yeast(display_long)|uniprotkb:DNF1(gene name)|psi-mi:DNF1(display_short)|uniprotkb:YER166W(locus name)|uniprotkb:SYGP-ORF7(orf name)|uniprotkb:Flippase DNF1(gene name synonym) psi-mi:atc4_yeast(display_long)|uniprotkb:DNF2(gene name)|psi-mi:DNF2(display_short)|uniprotkb:YDR093W(locus name)|uniprotkb:YD8557.01(orf name)|uniprotkb:Flippase DNF2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319412|imex:IM-26944-447 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000968|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR026871|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:7KY6|rcsb pdb:7KYB|rcsb pdb:7KYC|refseq:NP_011093.3|dip:DIP-7949N|mint:P32660|ensemblfungi:YER166W(gene)|ensemblfungi:YER166W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|ensemblgenomes:YER166W(identity) refseq:NP_010378.1|sgd:S000002500|dip:DIP-8055N|mint:Q12675|ensemblfungi:YDR093W(gene)|ensemblfungi:YDR093W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0015031"(protein transport)|go:"GO:0015247"(aminophospholipid flippase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140346"(phosphatidylserine flippase activity)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR026871|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:7KY5|rcsb pdb:7KY7|rcsb pdb:7KY8|rcsb pdb:7KY9|rcsb pdb:7KYA|ensemblgenomes:YDR093W(identity) - crc64:3CC3FBA8ADDE8960 - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:4ciEaV0aGjDqtpexkFJ0l737SpA559292 rogid:yfYH/L8WpAsxluGHGiYw3loRtRM559292 rigid:JHOki/TpxXmMpRQ/Eq8bAQpVpw4 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40092 uniprotkb:Q01589 intact:EBI-22721|uniprotkb:D3DM57|ensemblfungi:YER150W intact:EBI-16917|uniprotkb:D6VS63|uniprotkb:Q6Q5U8|uniprotkb:Q8J057|uniprotkb:Q8J270|uniprotkb:Q8J271|uniprotkb:Q8J272|uniprotkb:Q8J273|uniprotkb:Q8J274|uniprotkb:Q8J275|ensemblfungi:YDR077W psi-mi:spi1_yeast(display_long)|uniprotkb:YER150W(locus name)|uniprotkb:SPI1(gene name)|psi-mi:SPI1(display_short)|uniprotkb:Stationary phase-induced protein 1(gene name synonym) psi-mi:sed1_yeast(display_long)|uniprotkb:SED1(gene name)|psi-mi:SED1(display_short)|uniprotkb:YDR077W(locus name)|uniprotkb:D4431(orf name)|uniprotkb:Glycoprotein GP260(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319400|imex:IM-26944-645 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000952|refseq:NP_011077.1|dip:DIP-2064N|go:"GO:0071944"(cell periphery)|interpro:IPR038843|go:"GO:0031505"(fungal-type cell wall organization)|ensemblfungi:YER150W(gene)|ensemblfungi:YER150W_mRNA(transcript)|go:"GO:0005199"(structural constituent of cell wall)|go:"GO:0005576"(extracellular region)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0010447"(response to acidic pH)|go:"GO:0031225"(anchored component of membrane)|ensemblgenomes:YER150W(identity) refseq:NP_010362.3|sgd:S000002484|ensemblfungi:YDR077W(gene)|ensemblfungi:YDR077W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005199"(structural constituent of cell wall)|go:"GO:0005576"(extracellular region)|go:"GO:0005739"(mitochondrion)|go:"GO:0005840"(ribosome)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0071944"(cell periphery)|interpro:IPR038843|dip:DIP-1613N|ensemblgenomes:YDR077W(identity) - crc64:F65B20225FE2A5ED - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:0S1OQwJ9EXGKjALQ4oF2uW7KCjc559292 rogid:4Oyb3fialIFuwCLzsRFRcTML3ng559292 rigid:yiTQzeCT7auR0YEKea1+8Kv11Es false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53955 uniprotkb:P40485 intact:EBI-28706|uniprotkb:Q2VQW4|uniprotkb:D6W1D2|ensemblfungi:YNL047C intact:EBI-25172|uniprotkb:D6VVI2|ensemblfungi:YIL105C psi-mi:slm2_yeast(display_long)|uniprotkb:YNL047C(locus name)|uniprotkb:N2515(orf name)|uniprotkb:YNL2515P(orf name)|uniprotkb:SLM2(gene name)|psi-mi:SLM2(display_short)|uniprotkb:LIT1(gene name synonym)|uniprotkb:Synthetic lethal with MSS4 protein 2(gene name synonym)|uniprotkb:TORC2 effector protein SLM2(gene name synonym) psi-mi:slm1_yeast(display_long)|uniprotkb:TORC2 effector protein SLM1(gene name synonym)|uniprotkb:Synthetic lethal with MSS4 protein 1(gene name synonym)|uniprotkb:YIL105C(locus name)|uniprotkb:SLM1(gene name)|psi-mi:SLM1(display_short)|uniprotkb:LIT2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319712|imex:IM-26944-303 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004992|refseq:NP_014351.3|dip:DIP-1269N|mint:P53955|ensemblfungi:YNL047C(gene)|ensemblfungi:YNL047C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031929"(TOR signaling)|go:"GO:0031932"(TORC2 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070941"(eisosome assembly)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR033191|interpro:IPR043453|ensemblgenomes:YNL047C(identity) refseq:NP_012161.1|sgd:S000001367|mint:P40485|dip:DIP-1353N|ensemblfungi:YIL105C(gene)|ensemblfungi:YIL105C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031929"(TOR signaling)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070941"(eisosome assembly)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR033191|interpro:IPR043453|rcsb pdb:3NSU|rcsb pdb:4A5K|rcsb pdb:4A6F|rcsb pdb:4A6H|rcsb pdb:4A6K|ensemblgenomes:YIL105C(identity) - crc64:85E65FE60312B875 crc64:849C82CC0960014B figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:z4U8XXxSP0OQE589yaovSrrcVwg559292 rogid:f0Gtntpff7Oav37jlVaggG2VI30559292 rigid:ip8e6wl47SGupdo9ZpEmYBXI1FE false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23292 uniprotkb:P23291 intact:EBI-4729|uniprotkb:D6W129|ensemblfungi:YNL154C intact:EBI-4718|uniprotkb:E9P958|uniprotkb:D3DL84|ensemblfungi:YHR135C psi-mi:kc12_yeast(display_long)|uniprotkb:YCK2(gene name)|psi-mi:YCK2(display_short)|uniprotkb:CKI1(gene name synonym)|uniprotkb:YNL154C(locus name)|uniprotkb:N1755(orf name) psi-mi:kc11_yeast(display_long)|uniprotkb:YCK1(gene name)|psi-mi:YCK1(display_short)|uniprotkb:CKI2(gene name synonym)|uniprotkb:YHR135C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319700|imex:IM-26944-653 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014245.1|sgd:S000005098|ensemblfungi:YNL154C(gene)|ensemblfungi:YNL154C_mRNA(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|dip:DIP-720N|mint:P23292|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005937"(mating projection)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0009749"(response to glucose)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|ensemblgenomes:YNL154C(identity) refseq:NP_012003.1|sgd:S000001177|dip:DIP-719N|mint:P23291|ensemblfungi:YHR135C(gene)|ensemblfungi:YHR135C_mRNA(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0009749"(response to glucose)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:5X18|ensemblgenomes:YHR135C(identity) - crc64:A88D99BC265BF4FA crc64:77344717818C2D17 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:1nUIikls1l+co991K+hA3Njzmuc559292 rogid:pFpwRNbvvNZ1NPc7VMVXSivwMeI559292 rigid:38nNhU2IJ8BwFisxQrh/6sfGtUk false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17898 uniprotkb:P22140 intact:EBI-2050738|uniprotkb:D6W152|ensemblfungi:YNL130C intact:EBI-6494|uniprotkb:D3DL73|ensemblfungi:YHR123W psi-mi:cpt1_yeast(display_long)|uniprotkb:Diacylglycerol cholinephosphotransferase 1(gene name synonym)|uniprotkb:Sn-1,2-diacylglycerol cholinephosphotransferase(gene name synonym)|uniprotkb:N1218(orf name)|uniprotkb:N1867(orf name)|uniprotkb:YNL130C(locus name)|uniprotkb:CPT1(gene name)|psi-mi:CPT1(display_short)|uniprotkb:Aminoalcohol phosphotransferase CPT1(gene name synonym) psi-mi:ept1_yeast(display_long)|uniprotkb:EPT1(gene name)|psi-mi:EPT1(display_short)|uniprotkb:Aminoalcohol phosphotransferase EPT1(gene name synonym)|uniprotkb:YHR123W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319688|imex:IM-26944-377 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005074|refseq:NP_014269.4|dip:DIP-7848N|mint:P17898|ensemblfungi:YNL130C(gene)|ensemblfungi:YNL130C_mRNA(transcript)|go:"GO:0004142"(diacylglycerol cholinephosphotransferase activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006657"(CDP-choline pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014472(Choline/ethanolaminephosphotransferase)|interpro:IPR043130|reactome:R-SCE-1483191|reactome:R-SCE-1483213|ensemblgenomes:YNL130C(identity) refseq:NP_011991.1|sgd:S000001165|mint:P22140|dip:DIP-5619N|ensemblfungi:YHR123W(gene)|ensemblfungi:YHR123W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004142"(diacylglycerol cholinephosphotransferase activity)|go:"GO:0004307"(ethanolaminephosphotransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006646"(phosphatidylethanolamine biosynthetic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR043130|reactome:R-SCE-1483191|reactome:R-SCE-1483213|interpro:IPR014472(Choline/ethanolaminephosphotransferase)|ensemblgenomes:YHR123W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:PsU8UELFPsbtbzOS6oBnXJAuk/A559292 rogid:CWeN5fKw1tHLle/Vgn+jmL/zrQk559292 rigid:cfvCSbgRZoDpyqKmb4ZXoIbaCsc false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38853 uniprotkb:P50090 intact:EBI-9619|ensemblfungi:YHR158C|uniprotkb:D3DLA7|uniprotkb:E9P8X4 intact:EBI-9630|ensemblfungi:YGR238C|uniprotkb:D6VV18 psi-mi:kel1_yeast(display_long)|uniprotkb:KEL1(gene name)|psi-mi:KEL1(display_short)|uniprotkb:YHR158C(locus name) psi-mi:kel2_yeast(display_long)|uniprotkb:KEL2(gene name)|psi-mi:KEL2(display_short)|uniprotkb:G8585(orf name)|uniprotkb:YGR238C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319676|imex:IM-26944-457 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR158C(gene)|ensemblfungi:YHR158C_mRNA(transcript)|go:"GO:0000755"(cytogamy)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0090337"(regulation of formin-nucleated actin cable assembly)|go:"GO:1990615"(Kelch-containing formin regulatory complex)|interpro:IPR015915(Kelch-type beta propeller)|refseq:NP_012028.1|sgd:S000001201|dip:DIP-1403N|mint:P38853|ensemblgenomes:YHR158C(identity) go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0090337"(regulation of formin-nucleated actin cable assembly)|go:"GO:1990615"(Kelch-containing formin regulatory complex)|interpro:IPR015915(Kelch-type beta propeller)|ensemblfungi:YGR238C(gene)|ensemblfungi:YGR238C_mRNA(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0008360"(regulation of cell shape)|refseq:NP_011754.3|sgd:S000003470|dip:DIP-4229N|mint:P50090|ensemblgenomes:YGR238C(identity) - crc64:43D0FC570F1D5E4D crc64:63B9772FF017E6D9 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:pdHtsxpdf1r7G2K9e9EPHajJS3w559292 rogid:lSnioafH7gyCBHbl539AXlWBAxE559292 rigid:j3fxfssltKjMoDuiB8X1j+KatoQ false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P22217 uniprotkb:P22803 intact:EBI-19607|uniprotkb:D6VY45|ensemblfungi:YLR043C intact:EBI-19598|uniprotkb:D6VUZ2|ensemblfungi:YGR209C psi-mi:trx1_yeast(display_long)|uniprotkb:TRX1(gene name)|psi-mi:TRX1(display_short)|uniprotkb:TRX2(gene name synonym)|uniprotkb:YLR043C(locus name)|uniprotkb:Thioredoxin I(gene name synonym)|uniprotkb:Thioredoxin-2(gene name synonym) psi-mi:trx2_yeast(display_long)|uniprotkb:TRX2(gene name)|psi-mi:TRX2(display_short)|uniprotkb:TRX1(gene name synonym)|uniprotkb:G7746(orf name)|uniprotkb:YGR209C(locus name)|uniprotkb:Thioredoxin II(gene name synonym)|uniprotkb:Thioredoxin-1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319664|imex:IM-26944-301 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013144.1|sgd:S000004033|interpro:IPR005746(Thioredoxin)|interpro:IPR017937|interpro:IPR013766(Thioredoxin domain)|ensemblfungi:YLR043C(gene)|ensemblfungi:YLR043C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0015031"(protein transport)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0080058"(protein deglutathionylation)|rcsb pdb:2I9H|rcsb pdb:2N5A|rcsb pdb:2N5B|rcsb pdb:3F3Q|rcsb pdb:3F3R|go:"GO:0006662"(glycerol ether metabolic process)|mint:P22217|interpro:IPR036249|ensemblgenomes:YLR043C(identity) sgd:S000003441|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0015031"(protein transport)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0080058"(protein deglutathionylation)|interpro:IPR005746(Thioredoxin)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|rcsb pdb:2FA4|rcsb pdb:2HSY|rcsb pdb:3PIN|rcsb pdb:4DSS|rcsb pdb:7BVV|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|ensemblfungi:YGR209C(gene)|ensemblfungi:YGR209C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000103"(sulfate assimilation)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006662"(glycerol ether metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|refseq:NP_011725.3|dip:DIP-5552N|mint:P22803|ensemblgenomes:YGR209C(identity) - - crc64:071503762C90D451 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:HTTjl3NGIuQllhjAI5NASyqqIlc559292 rogid:pRt9fGROPXW+o4g6ynOmCDiclFk559292 rigid:wIlIWFYYid3t71hgPsUZjoLgyn4 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06451 uniprotkb:P53283 intact:EBI-34275|uniprotkb:D6W4F2|ensemblfungi:YPR156C intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C psi-mi:tpo3_yeast(display_long)|uniprotkb:TPO3(gene name)|psi-mi:TPO3(display_short)|uniprotkb:P9584.7(orf name)|uniprotkb:YPR156C(locus name) psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319652|imex:IM-26944-651 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015482.1|sgd:S000006360|mint:Q06451|dip:DIP-3907N|ensemblfungi:YPR156C(gene)|ensemblfungi:YPR156C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259|ensemblgenomes:YPR156C(identity) refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259|ensemblgenomes:YGR138C(identity) - crc64:D260ED161F800502 - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:oVpx7Bjk/mK2Q7+/j05tX3gHw7k559292 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 rigid:vxufMYEfF3yv/hxJ0HlG7+0KsJw false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06449 uniprotkb:P53281 intact:EBI-35523|uniprotkb:D6W4F0|ensemblfungi:YPR154W intact:EBI-23329|uniprotkb:D6VUR8|ensemblfungi:YGR136W psi-mi:pin3_yeast(display_long)|uniprotkb:PIN3(gene name)|psi-mi:PIN3(display_short)|uniprotkb:LAS seventeen-binding protein 2(gene name synonym)|uniprotkb:LSB2(gene name synonym)|uniprotkb:YPR154W(locus name) psi-mi:lsb1_yeast(display_long)|uniprotkb:LSB1(gene name)|psi-mi:LSB1(display_short)|uniprotkb:YGR136W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319640|imex:IM-26944-455 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015480.1|sgd:S000006358|dip:DIP-6257N|ensemblfungi:YPR154W(gene)|ensemblfungi:YPR154W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|rcsb pdb:1YNZ|rcsb pdb:1ZX6|go:"GO:0030479"(actin cortical patch)|ensemblgenomes:YPR154W(identity) refseq:NP_011652.1|sgd:S000003368|dip:DIP-1863N|mint:P53281|ensemblfungi:YGR136W(gene)|ensemblfungi:YGR136W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030479"(actin cortical patch)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|ensemblgenomes:YGR136W(identity) - - crc64:5F0B1361AF84AA79 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:JeNsn3H/VROp194KQLL/o9IhY6Q559292 rogid:R1HwHYkR6yeO64d9A2xUBxvijvU559292 rigid:3ByB/AKfcFKzBUOjJPJ9pdyv0ZQ false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53390 uniprotkb:P40260 intact:EBI-10729|uniprotkb:Q6B2F5|ensemblfungi:YPR138C|uniprotkb:D6W4D6 intact:EBI-10714|ensemblfungi:YGR121C|uniprotkb:D6VUQ2 psi-mi:mep3_yeast(display_long)|uniprotkb:MEP3(gene name)|psi-mi:MEP3(display_short)|uniprotkb:YPR138C(locus name)|uniprotkb:P9659.14(orf name)|uniprotkb:AMT3(gene name synonym) psi-mi:mep1_yeast(display_long)|uniprotkb:MEP1(gene name)|psi-mi:MEP1(display_short)|uniprotkb:YGR121C(locus name)|uniprotkb:G6331(orf name)|uniprotkb:AMT1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319628|imex:IM-26944-453 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015464.1|sgd:S000006342|ensemblfungi:YPR138C(gene)|ensemblfungi:YPR138C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|mint:P53390|dip:DIP-4909N|ensemblgenomes:YPR138C(identity) ensemblfungi:YGR121C(gene)|ensemblfungi:YGR121C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|sgd:S000003353|refseq:NP_011636.3|mint:P40260|dip:DIP-5530N|ensemblgenomes:YGR121C(identity) - crc64:2309338F36D96258 - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:UajvXf1E8FU957+oquLoPeSfTjk559292 rogid:VnoBl5jhQD24N0SbCLv68HCwl1U559292 rigid:O/pzYx4h6t3Hrvh/1WrZd98IUwA false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06144 uniprotkb:P53224 intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W intact:EBI-12592|uniprotkb:D6VUH5|ensemblfungi:YGR038W psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:orm1_yeast(display_long)|uniprotkb:YGR038W(locus name)|uniprotkb:ORM1(gene name)|psi-mi:ORM1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319616|imex:IM-26944-209 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695|ensemblgenomes:YLR350W(identity) ensemblfungi:YGR038W(gene)|ensemblfungi:YGR038W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|refseq:NP_011552.1|sgd:S000003270|reactome:R-SCE-6798695|dip:DIP-8124N|ensemblgenomes:YGR038W(identity) - crc64:2F474503CAB7C195 crc64:4387D00ACE4F3A1D figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 rogid:HsbGN/V/sSXpez8xOIDmVo6oiSk559292 rigid:ZzX1dvxCkbh0tATcrDK+deJMMrU false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06178 uniprotkb:P53204 intact:EBI-11803|ensemblfungi:YLR328W|uniprotkb:D6VYX0 intact:EBI-23073|uniprotkb:D6VUE7|ensemblfungi:YGR010W psi-mi:nma1_yeast(display_long)|uniprotkb:NMA1(gene name)|psi-mi:NMA1(display_short)|uniprotkb:"NAD(+) pyrophosphorylase 1"(gene name synonym)|uniprotkb:"NAD(+) diphosphorylase 1"(gene name synonym)|uniprotkb:Nicotinamide-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:Nicotinate-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:L8543.16(orf name)|uniprotkb:YLR328W(locus name) psi-mi:nma2_yeast(display_long)|uniprotkb:NMA2(gene name)|psi-mi:NMA2(display_short)|uniprotkb:"NAD(+) pyrophosphorylase 2"(gene name synonym)|uniprotkb:"NAD(+) diphosphorylase 2"(gene name synonym)|uniprotkb:Nicotinamide-nucleotide adenylyltransferase 2(gene name synonym)|uniprotkb:Nicotinate-nucleotide adenylyltransferase 2(gene name synonym)|uniprotkb:YGR010W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319604|imex:IM-26944-299 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR328W(gene)|ensemblfungi:YLR328W_mRNA(transcript)|go:"GO:0000309"(nicotinamide-nucleotide adenylyltransferase activity)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|reactome:R-SCE-196807|refseq:NP_013432.1|sgd:S000004320|dip:DIP-1228N|mint:Q06178|ensemblgenomes:YLR328W(identity) refseq:NP_011524.1|sgd:S000003242|dip:DIP-1227N|mint:P53204|ensemblfungi:YGR010W(gene)|ensemblfungi:YGR010W_mRNA(transcript)|go:"GO:0000309"(nicotinamide-nucleotide adenylyltransferase activity)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0009435"(NAD biosynthetic process)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|reactome:R-SCE-196807|ensemblgenomes:YGR010W(identity) - crc64:A176964E56A30DD8 - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:VzrKsykGbQsR8Eh7CHCwn/bCID8559292 rogid:AdSZgVYoChR4aYSPC7gsAQ5Pws0559292 rigid:kWSUw3O+zKVlUCxmrFscRQB1Qpk false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06169 uniprotkb:P53203 intact:EBI-31008|intact:EBI-937900|uniprotkb:Q66R43|uniprotkb:D6VYW6|ensemblfungi:YLR324W intact:EBI-23069|uniprotkb:D6VUE1|ensemblfungi:YGR004W psi-mi:pex30_yeast(display_long)|uniprotkb:PEX30(gene name)|psi-mi:PEX30(display_short)|uniprotkb:Peroxin-30(gene name synonym)|uniprotkb:YLR324W(locus name) psi-mi:pex31_yeast(display_long)|uniprotkb:Peroxin-31(gene name synonym)|uniprotkb:PEX31(gene name)|psi-mi:PEX31(display_short)|uniprotkb:YGR004W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319592|imex:IM-26944-297 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013428.1|sgd:S000004316|dip:DIP-1800N|mint:Q06169|ensemblfungi:YLR324W(gene)|ensemblfungi:YLR324W_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005933"(cellular bud)|go:"GO:0007031"(peroxisome organization)|go:"GO:0032581"(ER-dependent peroxisome organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071944"(cell periphery)|go:"GO:0097749"(membrane tubulation)|go:"GO:1900063"(regulation of peroxisome organization)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR010482(Integral peroxisomal membrane peroxin)|ensemblgenomes:YLR324W(identity) refseq:NP_011518.1|sgd:S000003236|dip:DIP-5455N|ensemblfungi:YGR004W(gene)|ensemblfungi:YGR004W_mRNA(transcript)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007031"(peroxisome organization)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071944"(cell periphery)|go:"GO:0097749"(membrane tubulation)|go:"GO:1900063"(regulation of peroxisome organization)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR010482(Integral peroxisomal membrane peroxin)|ensemblgenomes:YGR004W(identity) - crc64:417DBE56B1C8B1D5 - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:vkvJ4GqSW60wMG0m3ChlSzwcC3c559292 rogid:A8m6e08wcV/TdPj9ks1r34U8G80559292 rigid:EiYd1PA6jGzHbdk58lvSJeSO6Zk false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P04807 uniprotkb:P04806 intact:EBI-8738|ensemblfungi:YGL253W|uniprotkb:Q05838|uniprotkb:D6VV82 intact:EBI-8732|ensemblfungi:YFR053C|uniprotkb:D6VTT6 psi-mi:hxkb_yeast(display_long)|uniprotkb:HKB(gene name synonym)|uniprotkb:NRB486(orf name)|uniprotkb:YGL253W(locus name)|uniprotkb:HXK2(gene name)|psi-mi:HXK2(display_short)|uniprotkb:HEX1(gene name synonym)|uniprotkb:Hexokinase-B(gene name synonym)|uniprotkb:Hexokinase PII(gene name synonym) psi-mi:hxka_yeast(display_long)|uniprotkb:HKA(gene name synonym)|uniprotkb:YFR053C(locus name)|uniprotkb:HXK1(gene name)|psi-mi:HXK1(display_short)|uniprotkb:Hexokinase-A(gene name synonym)|uniprotkb:Hexokinase PI(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319580|imex:IM-26944-207 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL253W(gene)|ensemblfungi:YGL253W_mRNA(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0004340"(glucokinase activity)|go:"GO:0004396"(hexokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005536"(glucose binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006013"(mannose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008361"(regulation of cell size)|go:"GO:0008865"(fructokinase activity)|go:"GO:0019158"(mannokinase activity)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032445"(fructose import)|go:"GO:0046015"(regulation of transcription by glucose)|go:"GO:0046323"(glucose import)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001312(Hexokinase)|interpro:IPR019807|interpro:IPR022672|interpro:IPR022673|interpro:IPR043129|rcsb pdb:1IG8|rcsb pdb:2YHX|rcsb pdb:5UWT|reactome:R-SCE-170822|reactome:R-SCE-6798695|reactome:R-SCE-70171|refseq:NP_011261.1|sgd:S000003222|mint:P04807|dip:DIP-2380N|ensemblgenomes:YGL253W(identity) ensemblfungi:YFR053C(gene)|ensemblfungi:YFR053C_mRNA(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0004340"(glucokinase activity)|go:"GO:0004396"(hexokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005536"(glucose binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006013"(mannose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008865"(fructokinase activity)|go:"GO:0019158"(mannokinase activity)|go:"GO:0032445"(fructose import)|go:"GO:0046323"(glucose import)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|interpro:IPR001312(Hexokinase)|interpro:IPR019807|interpro:IPR022672|interpro:IPR022673|interpro:IPR043129|rcsb pdb:1HKG|rcsb pdb:3B8A|reactome:R-SCE-170822|reactome:R-SCE-6798695|reactome:R-SCE-70171|refseq:NP_116711.3|sgd:S000001949|mint:P04806|dip:DIP-5377N|ensemblgenomes:YFR053C(identity) - crc64:D55FF3F8992B2FEF crc64:AF5C9DA8F17BC3D0 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:DGycg0nxbxnH7W3sJoM9k4t3qYc559292 rogid:zsmpb9CuEStI8OqnH/VF1X/c40A559292 rigid:JPGZ9XjXD5FMzrWyhWWlQNuWnro false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32793 uniprotkb:P43603 intact:EBI-24460|uniprotkb:D3DKW1|ensemblfungi:YHR016C intact:EBI-22980|uniprotkb:D6VTQ4|ensemblfungi:YFR024C-A psi-mi:ysc84_yeast(display_long)|uniprotkb:YSC84(gene name)|psi-mi:YSC84(display_short)|uniprotkb:LSB4(gene name synonym)|uniprotkb:LAS seventeen-binding protein 4(gene name synonym)|uniprotkb:YHR016C(locus name) psi-mi:lsb3_yeast(display_long)|uniprotkb:LSB3(gene name)|psi-mi:LSB3(display_short)|uniprotkb:YFR024C(orf name)|uniprotkb:YFR024C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319568|imex:IM-26944-295 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011880.1|sgd:S000001058|dip:DIP-2026N|mint:P32793|ensemblfungi:YHR016C(gene)|ensemblfungi:YHR016C_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization)|interpro:IPR001452(Src homology-3)|interpro:IPR007461(Protein of unknown function DUF500)|interpro:IPR033643|interpro:IPR036028|rcsb pdb:2A08|ensemblgenomes:YHR016C(identity) sgd:S000002968|refseq:NP_219497.4|dip:DIP-6259N|mint:P43603|ensemblfungi:YFR024C-A(gene)|ensemblfungi:YFR024C-A_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005935"(cellular bud neck)|go:"GO:0030479"(actin cortical patch)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization)|interpro:IPR001452(Src homology-3)|interpro:IPR007461(Protein of unknown function DUF500)|interpro:IPR033643|interpro:IPR036028|rcsb pdb:1OOT|rcsb pdb:1SSH|ensemblgenomes:YFR024C-A(identity) - crc64:DE42E8ECF5B83C92 crc64:F486C787B5771AAC figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:hirm/OlqdPxvJNPbha68BSFIvmQ559292 rogid:zKMZQRpG4d/at/NecQDyEi/kVKg559292 rigid:R8pjxQemMdqoLMS4NXpZfJUH2mE false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27472 uniprotkb:P23337 intact:EBI-8036|uniprotkb:D6VYQ5|ensemblfungi:YLR258W intact:EBI-8031|uniprotkb:D6VTP6|ensemblfungi:YFR015C psi-mi:gys2_yeast(display_long)|uniprotkb:L8479.8(orf name)|uniprotkb:YLR258W(locus name)|uniprotkb:GSY2(gene name)|psi-mi:GSY2(display_short) psi-mi:gys1_yeast(display_long)|uniprotkb:YFR015C(locus name)|uniprotkb:GSY1(gene name)|psi-mi:GSY1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319556|imex:IM-26944-293 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013359.1|sgd:S000004248|mint:P27472|dip:DIP-1255N|ensemblfungi:YLR258W(gene)|ensemblfungi:YLR258W_mRNA(transcript)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR008631(Glycogen synthase)|rcsb pdb:3NAZ|rcsb pdb:3NB0|rcsb pdb:3NCH|rcsb pdb:3O3C|rcsb pdb:3RSZ|rcsb pdb:3RT1|rcsb pdb:4KQ2|rcsb pdb:4KQM|rcsb pdb:5SUK|rcsb pdb:5SUL|rcsb pdb:5UW0|rcsb pdb:5UW1|rcsb pdb:5UW4|rcsb pdb:5UX7|rcsb pdb:5VNC|rcsb pdb:6U77|reactome:R-SCE-3322077|ensemblgenomes:YLR258W(identity) refseq:NP_116670.1|sgd:S000001911|mint:P23337|dip:DIP-5354N|ensemblfungi:YFR015C(gene)|ensemblfungi:YFR015C_mRNA(transcript)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005978"(glycogen biosynthetic process)|interpro:IPR008631(Glycogen synthase)|reactome:R-SCE-3322077|ensemblgenomes:YFR015C(identity) - crc64:4670D8328CEDB0D2 crc64:9EF2D3858529E68A figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:K8l8dzJOtoIWZHpDN8Bq31o6ahA559292 rogid:YDyqS1ELi4nkwAfLsPv+FNzh87k559292 rigid:WF0tBT7W556EEiv449ZQg/LMtTI false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12396 uniprotkb:P43555 intact:EBI-38641|uniprotkb:D6VY80|ensemblfungi:YLR080W intact:EBI-6439|uniprotkb:D6VTI2|ensemblfungi:YFL048C psi-mi:emp46_yeast(display_long)|uniprotkb:46 kDa endomembrane protein(gene name synonym)|uniprotkb:EMP46(gene name)|psi-mi:EMP46(display_short)|uniprotkb:YLR080W(locus name) psi-mi:emp47_yeast(display_long)|uniprotkb:YFL048C(locus name)|uniprotkb:EMP47(gene name)|psi-mi:EMP47(display_short)|uniprotkb:47 kDa endomembrane protein(gene name synonym)|uniprotkb:Endosomal P44 protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319544|imex:IM-26944-205 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013181.1|sgd:S000004070|dip:DIP-4209N|ensemblfungi:YLR080W(gene)|ensemblfungi:YLR080W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR016710(L-type lectin, fungi)|interpro:IPR035661|rcsb pdb:2A6V|rcsb pdb:2A6W|rcsb pdb:2A6X|ensemblgenomes:YLR080W(identity) refseq:NP_116606.1|sgd:S000001846|mint:P43555|dip:DIP-7675N|ensemblfungi:YFL048C(gene)|ensemblfungi:YFL048C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0097367"(carbohydrate derivative binding)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR016710(L-type lectin, fungi)|interpro:IPR035661|rcsb pdb:2A6Y|rcsb pdb:2A6Z|rcsb pdb:2A70|rcsb pdb:2A71|ensemblgenomes:YFL048C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:hCrYOuwXR3XzkMA6UecPqkakMn8559292 rogid:gq6bd7YuqqXJ+mHOhe1OZ0WU3K4559292 rigid:ted8vbJvUcUkHmQciYQZWS452uk false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40510 uniprotkb:P40054 intact:EBI-16821|ensemblfungi:YIL074C|uniprotkb:D6VVL0 intact:EBI-16961|uniprotkb:D3DLY8|ensemblfungi:YER081W psi-mi:ser33_yeast(display_long)|uniprotkb:SER33(gene name)|psi-mi:SER33(display_short)|uniprotkb:2-oxoglutarate reductase(gene name synonym)|uniprotkb:YIL074C(locus name) psi-mi:sera_yeast(display_long)|uniprotkb:SER3(gene name)|psi-mi:SER3(display_short)|uniprotkb:2-oxoglutarate reductase(gene name synonym)|uniprotkb:YER081W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319532|imex:IM-26944-375 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|refseq:NP_012191.1|sgd:S000001336|ensemblfungi:YIL074C(gene)|ensemblfungi:YIL074C_mRNA(transcript)|go:"GO:0004617"(phosphoglycerate dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0009070"(serine family amino acid biosynthetic process)|go:"GO:0016618"(hydroxypyruvate reductase activity)|go:"GO:0030267"("glyoxylate reductase (NADP+) activity")|go:"GO:0042802"(identical protein binding)|go:"GO:0051287"(NAD binding)|go:"GO:0061759"(alpha-ketoglutarate reductase activity)|interpro:IPR002912(Amino acid-binding ACT)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|dip:DIP-4483N|mint:P40510|ensemblgenomes:YIL074C(identity) refseq:NP_011004.3|sgd:S000000883|ensemblfungi:YER081W(gene)|ensemblfungi:YER081W_mRNA(transcript)|go:"GO:0004617"(phosphoglycerate dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0009070"(serine family amino acid biosynthetic process)|go:"GO:0016618"(hydroxypyruvate reductase activity)|go:"GO:0030267"("glyoxylate reductase (NADP+) activity")|go:"GO:0051287"(NAD binding)|go:"GO:0061759"(alpha-ketoglutarate reductase activity)|interpro:IPR002912(Amino acid-binding ACT)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|dip:DIP-5336N|mint:P40054|ensemblgenomes:YER081W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:EL+xZKwWXRcTkChe3CLKM+/WIzI559292 rogid:liGD7+FpTgCZYiHWbejPHNYk6As559292 rigid:mBKQPGn7agf1dJ0JQb/YOedJuig false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21373 uniprotkb:P32622 intact:EBI-20174|uniprotkb:Q54AD8|uniprotkb:D6VWM0|uniprotkb:E9P8Y8|ensemblfungi:YJR049C intact:EBI-22350|uniprotkb:D3DLK8|ensemblfungi:YEL041W psi-mi:utr1_yeast(display_long)|uniprotkb:UTR1(gene name)|psi-mi:UTR1(display_short)|uniprotkb:YJR049C(locus name)|uniprotkb:J1655(orf name)|uniprotkb:Unknown transcript 1 protein(gene name synonym) psi-mi:yef1_yeast(display_long)|uniprotkb:YEF1(gene name)|psi-mi:YEF1(display_short)|uniprotkb:SYGP-ORF17(orf name)|uniprotkb:YEL041W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319520|imex:IM-26944-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012583.1|sgd:S000003810|ensemblfungi:YJR049C(gene)|ensemblfungi:YJR049C_mRNA(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0042736"(NADH kinase activity)|interpro:IPR002504(ATP-NAD/AcoX kinase)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017437(ATP-NAD kinase, PpnK-type, all-beta)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|reactome:R-SCE-196807|mint:P21373|dip:DIP-4479N|ensemblgenomes:YJR049C(identity) refseq:NP_010873.1|sgd:S000000767|dip:DIP-1885N|mint:P32622|ensemblfungi:YEL041W(gene)|ensemblfungi:YEL041W_mRNA(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0042736"(NADH kinase activity)|interpro:IPR002504(ATP-NAD/AcoX kinase)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017437(ATP-NAD kinase, PpnK-type, all-beta)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|ensemblgenomes:YEL041W(identity) - crc64:1BF4F01D7213B94B crc64:E8301D466249DA27 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:l/mDQcBTaLoGMxT50H2W7npbw2g559292 rogid:HAL9emGKdVRCmdDG9CMzn68CGUI559292 rigid:40Q3rHri2jb0bgcJCtCNaU+vH8c false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10659 uniprotkb:P19358 intact:EBI-10789|ensemblfungi:YLR180W|uniprotkb:D6VYI4 intact:EBI-10795|uniprotkb:E9P927|ensemblfungi:YDR502C|uniprotkb:D6VTC4 psi-mi:metk1_yeast(display_long)|uniprotkb:SAM1(gene name)|psi-mi:SAM1(display_short)|uniprotkb:ETH10(gene name synonym)|uniprotkb:YLR180W(locus name)|uniprotkb:L9470.9(orf name)|uniprotkb:Methionine adenosyltransferase 1(gene name synonym) psi-mi:metk2_yeast(display_long)|uniprotkb:SAM2(gene name)|psi-mi:SAM2(display_short)|uniprotkb:ETH2(gene name synonym)|uniprotkb:YDR502C(locus name)|uniprotkb:D9719.8(orf name)|uniprotkb:Methionine adenosyltransferase 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319508|imex:IM-26944-649 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR180W(gene)|ensemblfungi:YLR180W_mRNA(transcript)|go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006555"(methionine metabolic process)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0046872"(metal ion binding)|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022628|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636|reactome:R-SCE-156581|reactome:R-SCE-1614635|reactome:R-SCE-2408508|refseq:NP_013281.1|sgd:S000004170|mint:P10659|dip:DIP-6667N|ensemblgenomes:YLR180W(identity) ensemblfungi:YDR502C(gene)|ensemblfungi:YDR502C_mRNA(transcript)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0046872"(metal ion binding)|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022628|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636|reactome:R-SCE-156581|reactome:R-SCE-1614635|reactome:R-SCE-2408508|go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006555"(methionine metabolic process)|sgd:S000002910|refseq:NP_010790.3|mint:P19358|dip:DIP-4001N|ensemblgenomes:YDR502C(identity) - crc64:18F82FC809EE4706 crc64:0AFCB0BA386F088B figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:PmIeDsMIksGSxihwmK1DqLFOItc559292 rogid:fLg9TMOk+nR4ZuRNqkqur0qzv/E559292 rigid:yn3DNVCSSXgU0gO6Y/BV7nnUvuY false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12236 uniprotkb:Q03407 intact:EBI-9844|intact:EBI-2935811|uniprotkb:D6W1W8|ensemblfungi:YOL100W intact:EBI-32467|uniprotkb:D6VTB3|ensemblfungi:YDR490C psi-mi:pkh2_yeast(display_long)|uniprotkb:YOL100W(locus name)|uniprotkb:HRC1081(orf name)|uniprotkb:PKH2(gene name)|psi-mi:PKH2(display_short)|uniprotkb:PKB-activating kinase homolog 2(gene name synonym) psi-mi:pkh1_yeast(display_long)|uniprotkb:3-phosphoinositide-dependent protein kinase 1(gene name synonym)|uniprotkb:PKH1(gene name)|psi-mi:PKH1(display_short)|uniprotkb:YDR490C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319496|imex:IM-26944-373 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014541.1|sgd:S000005460|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0060211"("regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|ensemblfungi:YOL100W(gene)|ensemblfungi:YOL100W_mRNA(transcript)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039046|reactome:R-SCE-114604|reactome:R-SCE-1257604|reactome:R-SCE-165158|reactome:R-SCE-202424|reactome:R-SCE-2730905|reactome:R-SCE-389357|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0004672"(protein kinase activity)|reactome:R-SCE-392451|reactome:R-SCE-5218920|reactome:R-SCE-5218921|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-6804757|reactome:R-SCE-9634635|reactome:R-SCE-5625740|dip:DIP-6295N|mint:Q12236|ensemblgenomes:YOL100W(identity) sgd:S000002898|refseq:NP_010778.3|dip:DIP-1518N|mint:Q03407|ensemblfungi:YDR490C(gene)|ensemblfungi:YDR490C_mRNA(transcript)|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0060211"("regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039046|ensemblgenomes:YDR490C(identity) - crc64:BE0DD9D49AC2EBC3 crc64:7FFD32E8BE8BC367 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:KzJ+WGY+PylRDsK1olfak8IyuXM559292 rogid:hpsrmcmAD7P9gkV3cPpXuTNgTMc559292 rigid:xMvj3RRoGcUpOuRbl0GxoOtkkPo false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P26570 uniprotkb:P33329 intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 intact:EBI-13815|ensemblfungi:YDR436W|uniprotkb:D6VT63 psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:ppz2_yeast(display_long)|uniprotkb:PPZ2(gene name)|psi-mi:PPZ2(display_short)|uniprotkb:D9461.22(orf name)|uniprotkb:YDR436W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319484|imex:IM-26944-647 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N|ensemblgenomes:YML016C(identity) ensemblfungi:YDR436W(gene)|ensemblfungi:YDR436W_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0046872"(metal ion binding)|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|go:"GO:0106306"|refseq:NP_010724.1|sgd:S000002844|mint:P33329|dip:DIP-6355N|ensemblgenomes:YDR436W(identity) - crc64:8B7F009521F72C15 crc64:3095F37046489AFB figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 rogid:WpYxSWimbMNz9ZdZHpezPp/B2Sc559292 rigid:/ZVn70UXbyyBm8DdVD/tUqmpM7U false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32324 uniprotkb:P32324 intact:EBI-6333|uniprotkb:Q6JEF7|uniprotkb:D6VT19|ensemblfungi:YDR385W|ensemblfungi:YOR133W intact:EBI-6333|uniprotkb:Q6JEF7|uniprotkb:D6VT19|ensemblfungi:YDR385W|ensemblfungi:YOR133W psi-mi:ef2_yeast(display_long)|uniprotkb:EFT1(gene name)|psi-mi:EFT1(display_short)|uniprotkb:YOR133W(locus name)|uniprotkb:O3317(orf name)|uniprotkb:YOR3317W(orf name)|uniprotkb:EFT2(gene name)|psi-mi:EFT2(display_short)|uniprotkb:YDR385W(locus name)|uniprotkb:Translation elongation factor 2(gene name synonym)|uniprotkb:Eukaryotic elongation factor 2(gene name synonym)|uniprotkb:Ribosomal translocase(gene name synonym) psi-mi:ef2_yeast(display_long)|uniprotkb:EFT1(gene name)|psi-mi:EFT1(display_short)|uniprotkb:YOR133W(locus name)|uniprotkb:O3317(orf name)|uniprotkb:YOR3317W(orf name)|uniprotkb:EFT2(gene name)|psi-mi:EFT2(display_short)|uniprotkb:YDR385W(locus name)|uniprotkb:Translation elongation factor 2(gene name synonym)|uniprotkb:Eukaryotic elongation factor 2(gene name synonym)|uniprotkb:Ribosomal translocase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319472|imex:IM-26944-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010673.1|refseq:NP_014776.1|sgd:S000005659|sgd:S000002793|ensemblfungi:YDR385W(gene)|ensemblfungi:YDR385W_mRNA(transcript)|ensemblfungi:YOR133W(gene)|ensemblfungi:YOR133W_mRNA(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0019843"(rRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0051087"(chaperone binding)|go:"GO:1990145"(maintenance of translational fidelity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|mint:P32324|dip:DIP-4911N|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|rcsb pdb:1N0U|rcsb pdb:1N0V|rcsb pdb:1U2R|rcsb pdb:1ZM2|rcsb pdb:1ZM3|rcsb pdb:1ZM4|rcsb pdb:1ZM9|rcsb pdb:2E1R|rcsb pdb:2NPF|rcsb pdb:2P8W|rcsb pdb:2P8X|rcsb pdb:2P8Y|rcsb pdb:2P8Z|rcsb pdb:2ZIT|rcsb pdb:3B78|rcsb pdb:3B82|rcsb pdb:3B8H|rcsb pdb:3DNY|rcsb pdb:4V4B|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|reactome:R-SCE-156902|reactome:R-SCE-5358493|reactome:R-SCE-6798695|ensemblgenomes:YOR133W(identity) refseq:NP_010673.1|refseq:NP_014776.1|sgd:S000005659|sgd:S000002793|ensemblfungi:YDR385W(gene)|ensemblfungi:YDR385W_mRNA(transcript)|ensemblfungi:YOR133W(gene)|ensemblfungi:YOR133W_mRNA(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0019843"(rRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0051087"(chaperone binding)|go:"GO:1990145"(maintenance of translational fidelity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|mint:P32324|dip:DIP-4911N|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|rcsb pdb:1N0U|rcsb pdb:1N0V|rcsb pdb:1U2R|rcsb pdb:1ZM2|rcsb pdb:1ZM3|rcsb pdb:1ZM4|rcsb pdb:1ZM9|rcsb pdb:2E1R|rcsb pdb:2NPF|rcsb pdb:2P8W|rcsb pdb:2P8X|rcsb pdb:2P8Y|rcsb pdb:2P8Z|rcsb pdb:2ZIT|rcsb pdb:3B78|rcsb pdb:3B82|rcsb pdb:3B8H|rcsb pdb:3DNY|rcsb pdb:4V4B|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|reactome:R-SCE-156902|reactome:R-SCE-5358493|reactome:R-SCE-6798695|ensemblgenomes:YDR385W(identity) - crc64:FD2F8073CB9B66AA crc64:FD2F8073CB9B66AA figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:mlyt9YKZrGhGbsSlvxNJ0p1C67I559292 rogid:mlyt9YKZrGhGbsSlvxNJ0p1C67I559292 rigid:jWPbFhrzSUX8llcuPU1CyVbbIq4 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38816 uniprotkb:P29509 intact:EBI-19502|uniprotkb:D3DL56|ensemblfungi:YHR106W intact:EBI-19497|uniprotkb:D6VSY3|ensemblfungi:YDR353W psi-mi:trxb2_yeast(display_long)|uniprotkb:YHR106W(locus name)|uniprotkb:TRR2(gene name)|psi-mi:TRR2(display_short) psi-mi:trxb1_yeast(display_long)|uniprotkb:D9476.5(orf name)|uniprotkb:YDR353W(locus name)|uniprotkb:TRR1(gene name)|psi-mi:TRR1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319460|imex:IM-26944-451 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011974.1|sgd:S000001148|ensemblfungi:YHR106W_mRNA(transcript)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0045454"(cell redox homeostasis)|interpro:IPR005982(Thioredoxin reductase)|interpro:IPR008255(Pyridine nucleotide-disulphide oxidoreductase, class-II, active site)|interpro:IPR023753|interpro:IPR036188|ensemblfungi:YHR106W(gene)|dip:DIP-1942N|mint:P38816|ensemblgenomes:YHR106W(identity) refseq:NP_010640.1|sgd:S000002761|ensemblfungi:YDR353W(gene)|ensemblfungi:YDR353W_mRNA(transcript)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0045454"(cell redox homeostasis)|interpro:IPR005982(Thioredoxin reductase)|interpro:IPR008255(Pyridine nucleotide-disulphide oxidoreductase, class-II, active site)|interpro:IPR023753|interpro:IPR036188|rcsb pdb:3D8X|rcsb pdb:3ITJ|dip:DIP-4319N|mint:P29509|ensemblgenomes:YDR353W(identity) - - crc64:9F9E58A4BAD859E1 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:MAzmQD74M9HfIswXAdQazKDYJvo559292 rogid:mDyO+A1dOgzMtGEDZ5D6nQfqHkw559292 rigid:dbmYS33+eeb9FG8nMXWiZDsgDk4 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38695 uniprotkb:P32466 intact:EBI-8778|ensemblfungi:YHR096C|uniprotkb:D3DL46 intact:EBI-8770|ensemblfungi:YDR345C|uniprotkb:D6VSX5 psi-mi:hxt5_yeast(display_long)|uniprotkb:YHR096C(locus name)|uniprotkb:HXT5(gene name)|psi-mi:HXT5(display_short) psi-mi:hxt3_yeast(display_long)|uniprotkb:D9651.14(orf name)|uniprotkb:YDR345C(locus name)|uniprotkb:HXT3(gene name)|psi-mi:HXT3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319448|imex:IM-26944-541 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR096C(gene)|ensemblfungi:YHR096C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011964.1|sgd:S000001138|mint:P38695|dip:DIP-5594N|ensemblgenomes:YHR096C(identity) interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|interpro:IPR005828(General substrate transporter)|ensemblfungi:YDR345C(gene)|ensemblfungi:YDR345C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|refseq:NP_010632.1|sgd:S000002753|mint:P32466|dip:DIP-4178N|ensemblgenomes:YDR345C(identity) - crc64:6906721BAC1A5F87 - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:aZGrWmUu+AZ4G6qmTG+Z+p6i7hs559292 rogid:sklAjpmtbPADWjK3sLElxkiGw6k559292 rigid:pI5IgrKnGiyoZ9f0mHIuCvggfzE false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08412 uniprotkb:Q05610 intact:EBI-37580|uniprotkb:D6W2A8|ensemblfungi:YOR042W intact:EBI-31191|uniprotkb:Q66RE0|uniprotkb:D6VSQ5|ensemblfungi:YDR273W psi-mi:cue5_yeast(display_long)|uniprotkb:YOR042W(locus name)|uniprotkb:CUE5(gene name)|psi-mi:CUE5(display_short)|uniprotkb:Coupling of ubiquitin conjugation to ER degradation protein 5(gene name synonym) psi-mi:don1_yeast(display_long)|uniprotkb:DON1(gene name)|psi-mi:DON1(display_short)|uniprotkb:D9954.4(orf name)|uniprotkb:YDR273W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319436|imex:IM-26944-449 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014685.1|sgd:S000005568|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|mint:Q08412|interpro:IPR041807|ensemblfungi:YOR042W(gene)|ensemblfungi:YOR042W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0043130"(ubiquitin binding)|reactome:R-SCE-6798695|ensemblgenomes:YOR042W(identity) refseq:NP_010559.3|sgd:S000002681|dip:DIP-1577N|ensemblfungi:YDR273W(gene)|ensemblfungi:YDR273W_mRNA(transcript)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030476"(ascospore wall assembly)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0051301"(cell division)|go:"GO:0070056"(prospore membrane leading edge)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|interpro:IPR041807|ensemblgenomes:YDR273W(identity) - crc64:0D455F9AD637AC8D crc64:6E13542050862709 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:bUu2kNMFibdM8RUj460pMdBr2UA559292 rogid:lwba8lbFDuhj4kIx6JdrOVlRF0s559292 rigid:swkE5thr9agJeVmTwqHky8B4OzE false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29311 uniprotkb:P34730 intact:EBI-3661|uniprotkb:Q06854|uniprotkb:D3DM86|ensemblfungi:YER177W intact:EBI-3672|uniprotkb:A2TBP2|uniprotkb:Q06HN5|uniprotkb:D6VS86|ensemblfungi:YDR099W psi-mi:bmh1_yeast(display_long)|uniprotkb:YER177W(locus name)|uniprotkb:BMH1(gene name)|psi-mi:BMH1(display_short) psi-mi:bmh2_yeast(display_long)|uniprotkb:YD8557.08(orf name)|uniprotkb:YDR099W(locus name)|uniprotkb:BMH2(gene name)|psi-mi:BMH2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319424|imex:IM-26944-117 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000979|refseq:NP_011104.3|dip:DIP-4313N|mint:P29311|ensemblfungi:YER177W(gene)|ensemblfungi:YER177W_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030437"(ascospore formation)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0034221"(fungal-type cell wall chitin biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070842"(aggresome assembly)|go:"GO:0070873"(regulation of glycogen metabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:5N6N|rcsb pdb:6QK8|ensemblgenomes:YER177W(identity) sgd:S000002506|refseq:NP_010384.3|dip:DIP-1212N|mint:P34730|ensemblfungi:YDR099W(gene)|ensemblfungi:YDR099W_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0030437"(ascospore formation)|go:"GO:0034221"(fungal-type cell wall chitin biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0070873"(regulation of glycogen metabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|ensemblgenomes:YDR099W(identity) - crc64:0A234167E313688B crc64:74788A9103F129FB figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:RnX8tqsjlxM+7Mi+Thlhc1XrTy4559292 rogid:trVbn5NvV8o+49WbsQrvedJbAZI559292 rigid:cqqoPxCXDucOzgZgXn+VFzDqMu0 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02208 uniprotkb:P47035 intact:EBI-27048|uniprotkb:D6VX76|ensemblfungi:YKR010C intact:EBI-25953|uniprotkb:D6VWA8|ensemblfungi:YJL076W psi-mi:tof2_yeast(display_long)|uniprotkb:TOF2(gene name)|psi-mi:TOF2(display_short)|uniprotkb:YK109(orf name)|uniprotkb:YKR010C(locus name) psi-mi:net1_yeast(display_long)|uniprotkb:YJL076W(locus name)|uniprotkb:J1038(orf name)|uniprotkb:NET1(gene name)|psi-mi:NET1(display_short)|uniprotkb:CFI1(gene name synonym)|uniprotkb:ESC5(gene name synonym)|uniprotkb:SRM8(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319724|imex:IM-26944-543 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001718|refseq:NP_012935.3|mint:Q02208|dip:DIP-3803N|ensemblfungi:YKR010C(gene)|ensemblfungi:YKR010C_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007000"(nucleolus organization)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0070550"(rDNA condensation)|interpro:IPR018844|interpro:IPR043185|rcsb pdb:5HOI|rcsb pdb:5V3N|ensemblgenomes:YKR010C(identity) refseq:NP_012459.1|sgd:S000003612|mint:P47035|dip:DIP-5153N|ensemblfungi:YJL076W(gene)|ensemblfungi:YJL076W_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0007000"(nucleolus organization)|go:"GO:0007049"(cell cycle)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0030869"(RENT complex)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0051301"(cell division)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|interpro:IPR018844|interpro:IPR043185|ensemblgenomes:YJL076W(identity) - - crc64:80EDF9A8065EB5A2 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:JSZUcVEWUE0GXXKxkdC/l5MWeLc559292 rogid:yjUIbOfA/bCZE9nMIjYS1QTn6EI559292 rigid:9BuOg/53clKoial703CrkNj6MVU false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02829 uniprotkb:P15108 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 intact:EBI-8666|ensemblfungi:YMR186W|uniprotkb:D6W010 psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:hsc82_yeast(display_long)|uniprotkb:HSC82(gene name)|psi-mi:HSC82(display_short)|uniprotkb:YMR186W(locus name)|uniprotkb:YM8010.16(orf name)|uniprotkb:Heat shock protein Hsp90 constitutive isoform(gene name synonym)|uniprotkb:82 kDa heat shock cognate protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319856|imex:IM-26944-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N|ensemblgenomes:YPL240C(identity) interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:6XLB|rcsb pdb:6XLC|rcsb pdb:6XLD|rcsb pdb:6XLE|rcsb pdb:6XLF|ensemblfungi:YMR186W(gene)|ensemblfungi:YMR186W_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000723"(telomere maintenance)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|rcsb pdb:6XLG|rcsb pdb:6XLH|reactome:R-SCE-1474151|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-9009391|refseq:NP_013911.1|sgd:S000004798|mint:P15108|dip:DIP-1524N|ensemblgenomes:YMR186W(identity) - crc64:D7C35676D668FB63 crc64:DBD41524091B1F9B figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 rogid:A0Na3L9N4cl7acd9lSGiwKAYK1o559292 rigid:mkf5N3WU6LcBcEt0O0SlG6HEVaI false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38426 uniprotkb:P38427 intact:EBI-19448|uniprotkb:D6W087|uniprotkb:Q6B1W2|ensemblfungi:YMR261C intact:EBI-19638|uniprotkb:D6W0I5|ensemblfungi:YML100W psi-mi:tps3_yeast(display_long)|uniprotkb:TPS3(gene name)|psi-mi:TPS3(display_short)|uniprotkb:YMR261C(locus name)|uniprotkb:YM8156.03C(orf name)|uniprotkb:Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 115 kDa subunit(gene name synonym) psi-mi:tsl1_yeast(display_long)|uniprotkb:TSL1(gene name)|psi-mi:TSL1(display_short)|uniprotkb:YML100W(locus name)|uniprotkb:Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 123 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319844|imex:IM-26944-127 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013988.1|sgd:S000004874|ensemblfungi:YMR261C(gene)|ensemblfungi:YMR261C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005946"("alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)")|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0016311"(dephosphorylation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR001830(Glycosyl transferase, family 20)|interpro:IPR003337(Trehalose-phosphatase)|interpro:IPR036412|dip:DIP-891N|mint:P38426|ensemblgenomes:YMR261C(identity) refseq:NP_013608.1|sgd:S000004566|ensemblfungi:YML100W(gene)|ensemblfungi:YML100W_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005946"("alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)")|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0016311"(dephosphorylation)|go:"GO:0030234"(enzyme regulator activity)|interpro:IPR001830(Glycosyl transferase, family 20)|interpro:IPR003337(Trehalose-phosphatase)|interpro:IPR036412|dip:DIP-753N|mint:P38427|ensemblgenomes:YML100W(identity) - - crc64:EA0A8A86AF178F04 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:aY+Gu2+xxYxfe40pjJ1KTaYbDxM559292 rogid:c83+6JC2tSJt4Z06mI3KDmHI1iM559292 rigid:dxxYNbt5LFQ2eZOAZZ7swyPpip8 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P12683 uniprotkb:P12684 intact:EBI-8377|uniprotkb:D6W0K8|ensemblfungi:YML075C intact:EBI-8384|uniprotkb:E9P8X3|uniprotkb:D6VZ84|ensemblfungi:YLR450W psi-mi:hmdh1_yeast(display_long)|uniprotkb:YML075C(locus name)|uniprotkb:HMG1(gene name)|psi-mi:HMG1(display_short) psi-mi:hmdh2_yeast(display_long)|uniprotkb:L9324.2(orf name)|uniprotkb:YLR450W(locus name)|uniprotkb:HMG2(gene name)|psi-mi:HMG2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319832|imex:IM-26944-125 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013636.1|sgd:S000004540|mint:P12683|dip:DIP-4529N|ensemblfungi:YML075C(gene)|ensemblfungi:YML075C_mRNA(transcript)|go:"GO:0004420"("hydroxymethylglutaryl-CoA reductase (NADPH) activity")|go:"GO:0005635"(nuclear envelope)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008299"(isoprenoid biosynthetic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0019287"(isopentenyl diphosphate biosynthetic process, mevalonate pathway)|go:"GO:0034399"(nuclear periphery)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR002202(Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic)|interpro:IPR004554(Hydroxymethylglutaryl-CoA reductase, class I, catalytic)|interpro:IPR009023(Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding)|interpro:IPR009029(Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding)|interpro:IPR023074|interpro:IPR023076|interpro:IPR023282|interpro:IPR025583|reactome:R-SCE-191273|ensemblgenomes:YML075C(identity) refseq:NP_013555.1|sgd:S000004442|mint:P12684|dip:DIP-6277N|ensemblfungi:YLR450W(gene)|ensemblfungi:YLR450W_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004420"("hydroxymethylglutaryl-CoA reductase (NADPH) activity")|go:"GO:0005635"(nuclear envelope)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008299"(isoprenoid biosynthetic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0034399"(nuclear periphery)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR002202(Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic)|interpro:IPR004554(Hydroxymethylglutaryl-CoA reductase, class I, catalytic)|interpro:IPR009023(Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding)|interpro:IPR009029(Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding)|interpro:IPR023074|interpro:IPR023076|interpro:IPR023282|interpro:IPR025583|ensemblgenomes:YLR450W(identity) - - crc64:1FD9DCD3AC01B15E figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:S+uIZsMovFNW2+PxvV7m76Jbh+o559292 rogid:6q1hM5csy4DSYUsSGyTr8M6b9r0559292 rigid:Hz3lN9+lbJc7Nrj6KunRgryHPjc false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38911 uniprotkb:Q06205 intact:EBI-6951|uniprotkb:D6W0K9|ensemblfungi:YML074C intact:EBI-6956|uniprotkb:D6VZ83|ensemblfungi:YLR449W psi-mi:fkbp3_yeast(display_long)|uniprotkb:YML074C(locus name)|uniprotkb:FPR3(gene name)|psi-mi:FPR3(display_short)|uniprotkb:NPI46(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Proline rotamase(gene name synonym)|uniprotkb:Nucleolar proline isomerase(gene name synonym)|uniprotkb:FKBP-70(gene name synonym) psi-mi:fkbp4_yeast(display_long)|uniprotkb:FPR4(gene name)|psi-mi:FPR4(display_short)|uniprotkb:YLR449W(locus name)|uniprotkb:L9324.3(orf name)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:Histone proline isomerase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319820|imex:IM-26944-123 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013637.1|sgd:S000004539|dip:DIP-6578N|ensemblfungi:YML074C(gene)|ensemblfungi:YML074C_mRNA(transcript)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR023566|interpro:IPR041232|ensemblgenomes:YML074C(identity) sgd:S000004441|refseq:NP_013554.3|dip:DIP-909N|mint:Q06205|ensemblfungi:YLR449W(gene)|ensemblfungi:YLR449W_mRNA(transcript)|go:"GO:0000412"(histone peptidyl-prolyl isomerization)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR023566|interpro:IPR041232|rcsb pdb:4BF8|ensemblgenomes:YLR449W(identity) - crc64:A01D24DE0078FE11 crc64:CF90C6714F04572E figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:4xZebf94akWQyMgPLbH6ExNGjoY559292 rogid:rDmDSGEgRbtgkLBoJTzmzxxY7B4559292 rigid:gtgkkxFhLnG/KFfcilKsuHcS9Y8 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50094 uniprotkb:P50095 intact:EBI-9195|ensemblfungi:YML056C|uniprotkb:Q2VQW8|uniprotkb:D6VZB8 intact:EBI-9190|ensemblfungi:YLR432W|uniprotkb:D6VZ67 psi-mi:imdh4_yeast(display_long)|uniprotkb:IMD4(gene name)|psi-mi:IMD4(display_short)|uniprotkb:YM9958.06C(orf name)|uniprotkb:YML056C(locus name) psi-mi:imdh3_yeast(display_long)|uniprotkb:IMD3(gene name)|psi-mi:IMD3(display_short)|uniprotkb:L9753.4(orf name)|uniprotkb:YLR432W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319808|imex:IM-26944-121 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML056C(gene)|ensemblfungi:YML056C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|reactome:R-SCE-6798695|reactome:R-SCE-73817|refseq:NP_013656.1|sgd:S000004520|dip:DIP-6458N|mint:P50094|ensemblgenomes:YML056C(identity) ensemblfungi:YLR432W(gene)|ensemblfungi:YLR432W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|reactome:R-SCE-6798695|reactome:R-SCE-73817|refseq:NP_013536.3|sgd:S000004424|dip:DIP-1947N|mint:P50095|ensemblgenomes:YLR432W(identity) - crc64:A73D1E4EFE8AEAD9 crc64:A0C84C22527AAEA6 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:S70ravpil5p+waXS1zst4Ii27dY559292 rogid:UUEyn+zhL8Z1aasK3r/inGhtO1c559292 rigid:gwC+jW4uS2Uppr5O3GHhTj871WM false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38009 uniprotkb:P54113 intact:EBI-14223|ensemblfungi:YMR120C|uniprotkb:D6VZU3 intact:EBI-14213|uniprotkb:E9PAG6|ensemblfungi:YLR028C|uniprotkb:D6VY30 psi-mi:pur92_yeast(display_long)|uniprotkb:ADE17(gene name)|psi-mi:ADE17(display_short)|uniprotkb:YM8564.02C(orf name)|uniprotkb:YMR120C(locus name) psi-mi:pur91_yeast(display_long)|uniprotkb:ADE16(gene name)|psi-mi:ADE16(display_short)|uniprotkb:YLR028C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319784|imex:IM-26944-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013839.1|sgd:S000004727|ensemblfungi:YMR120C(gene)|ensemblfungi:YMR120C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|reactome:R-SCE-73817|interpro:IPR036914|mint:P38009|dip:DIP-6288N|ensemblgenomes:YMR120C(identity) mint:P54113|refseq:NP_013128.1|sgd:S000004018|ensemblfungi:YLR028C(gene)|ensemblfungi:YLR028C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|interpro:IPR036914|dip:DIP-4657N|ensemblgenomes:YLR028C(identity) - crc64:8ABA71761B512242 - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:Bwp78WXy91CpBBXEqmM7MQV7XJk559292 rogid:SbZvY+c2tg098pE/sezKQp+3cFE559292 rigid:4p+2fbkcYZWPnZ/Hz+TVa+/s+Xw false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12123 uniprotkb:Q06151 intact:EBI-38701|uniprotkb:D6W2M9|ensemblfungi:YOR173W intact:EBI-38973|uniprotkb:Q6Q5L1|uniprotkb:D6VYR7|ensemblfungi:YLR270W psi-mi:dcs2_yeast(display_long)|uniprotkb:Histidine triad protein(gene name synonym)|uniprotkb:DCS2(gene name)|psi-mi:DCS2(display_short)|uniprotkb:Protein Dcs2p(gene name synonym)|uniprotkb:O3625(orf name)|uniprotkb:YOR173W(locus name) psi-mi:dcps_yeast(display_long)|uniprotkb:DCS-1(gene name synonym)|uniprotkb:Hint-related 7meGMP-directed hydrolase 1(gene name synonym)|uniprotkb:DCS1(gene name)|psi-mi:DCS1(display_short)|uniprotkb:Scavenger mRNA-decapping enzyme DcpS(gene name synonym)|uniprotkb:YLR270W(locus name)|uniprotkb:Protein Dcs1p(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319796|imex:IM-26944-213 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014816.2|sgd:S000005699|mint:Q12123|dip:DIP-4135N|ensemblfungi:YOR173W(gene)|ensemblfungi:YOR173W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007584"(response to nutrient)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009408"(response to heat)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0090342"(regulation of cell aging)|interpro:IPR008594(Scavenger mRNA decapping enzyme)|interpro:IPR011145(Scavenger mRNA decapping enzyme, N-terminal)|interpro:IPR019808|interpro:IPR036265|ensemblgenomes:YOR173W(identity) refseq:NP_013372.1|sgd:S000004260|mint:Q06151|dip:DIP-1480N|ensemblfungi:YLR270W(gene)|ensemblfungi:YLR270W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007584"(response to nutrient)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009408"(response to heat)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0031086"(nuclear-transcribed mRNA catabolic process, deadenylation-independent decay)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044692"(exoribonuclease activator activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0090342"(regulation of cell aging)|go:"GO:1901919"(positive regulation of exoribonuclease activity)|interpro:IPR008594(Scavenger mRNA decapping enzyme)|interpro:IPR011145(Scavenger mRNA decapping enzyme, N-terminal)|interpro:IPR019808|interpro:IPR036265|rcsb pdb:5BV3|rcsb pdb:6TRQ|reactome:R-SCE-429958|ensemblgenomes:YLR270W(identity) - crc64:B76D89C0816019A4 crc64:06A57C2344A3580A figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:aQPcvWgnqKehPYywuexsUkmjU9Q559292 rogid:63HqohkJUuNuZVKy4HcD1f0gGCg559292 rigid:pily5hY7v8hqzDFwVnYJPZ/CsMk false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12043 uniprotkb:P36165 intact:EBI-34845|uniprotkb:Q7LH13|uniprotkb:D6W2E4|ensemblfungi:YOR081C intact:EBI-26531|uniprotkb:D6VXE9|ensemblfungi:YKR089C psi-mi:tgl5_yeast(display_long)|uniprotkb:TGL5(gene name)|psi-mi:TGL5(display_short)|uniprotkb:STC2(gene name synonym)|uniprotkb:YOR29-32(orf name)|uniprotkb:YOR2964C(orf name)|uniprotkb:YOR081C(locus name)|uniprotkb:Lipase 5(gene name synonym) psi-mi:tgl4_yeast(display_long)|uniprotkb:YKR089C(locus name)|uniprotkb:YKR409(orf name)|uniprotkb:TGL4(gene name)|psi-mi:TGL4(display_short)|uniprotkb:STC1(gene name synonym)|uniprotkb:Lipase 4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319772|imex:IM-26944-459 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014724.1|sgd:S000005607|mint:Q12043|dip:DIP-6280N|ensemblfungi:YOR081C(gene)|ensemblfungi:YOR081C_mRNA(transcript)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042171"(lysophosphatidic acid acyltransferase activity)|interpro:IPR002641(Patatin)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR021771|ensemblgenomes:YOR081C(identity) refseq:NP_013015.1|sgd:S000001797|mint:P36165|dip:DIP-5588N|ensemblfungi:YKR089C(gene)|ensemblfungi:YKR089C_mRNA(transcript)|go:"GO:0004771"(sterol esterase activity)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0007114"(cell budding)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042171"(lysophosphatidic acid acyltransferase activity)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|interpro:IPR002641(Patatin)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR021771|ensemblgenomes:YKR089C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:ccHxygbWfyyQXKaSbOL4iYhikms559292 rogid:VEfeOj6QZCY2MIMeme5kaVZBQx8559292 rigid:0S1qggrwBpCfpH7+pxbbm9xI2Cg false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08438 uniprotkb:P36024 intact:EBI-30482|uniprotkb:O00019|uniprotkb:D6W2B8|ensemblfungi:YOR054C intact:EBI-17250|uniprotkb:D6VXD3|ensemblfungi:YKR072C psi-mi:vhs3_yeast(display_long)|uniprotkb:Viable in a HAL3 SIT4 background protein 3(gene name synonym)|uniprotkb:VHS3(gene name)|psi-mi:VHS3(display_short)|uniprotkb:YOR054C(locus name)|uniprotkb:YOR29-05(orf name) psi-mi:sis2_yeast(display_long)|uniprotkb:SIS2(gene name)|psi-mi:SIS2(display_short)|uniprotkb:HAL3(gene name synonym)|uniprotkb:YKR072C(locus name)|uniprotkb:Halotolerance protein HAL3(gene name synonym)|uniprotkb:Sit4 suppressor 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319760|imex:IM-26944-655 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014697.1|sgd:S000005580|dip:DIP-4172N|mint:Q08438|ensemblfungi:YOR054C(gene)|ensemblfungi:YOR054C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0007049"(cell cycle)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0030004"(cellular monovalent inorganic cation homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|ensemblgenomes:YOR054C(identity) refseq:NP_012998.1|sgd:S000001780|ensemblfungi:YKR072C(gene)|ensemblfungi:YKR072C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003824"(catalytic activity)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0009651"(response to salt stress)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|dip:DIP-2521N|mint:P36024|ensemblgenomes:YKR072C(identity) - crc64:A97623473CB6F605 - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:xBrkL/88mlDFkk10q3ASQnr0rv0559292 rogid:oiDiGYmZy7PE7zchnyTa2x4g9zo559292 rigid:g6uo5MivvWVo5qnpBLk0rVGtZBE false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36130 uniprotkb:P47025 intact:EBI-26394|uniprotkb:D6VX99|ensemblfungi:YKR036C intact:EBI-26032|uniprotkb:D6VW72|ensemblfungi:YJL112W psi-mi:caf4_yeast(display_long)|uniprotkb:YKR036C(locus name)|uniprotkb:CAF4(gene name)|psi-mi:CAF4(display_short) psi-mi:mdv1_yeast(display_long)|uniprotkb:YJL112W(locus name)|uniprotkb:J0802(orf name)|uniprotkb:MDV1(gene name)|psi-mi:MDV1(display_short)|uniprotkb:FIS2(gene name synonym)|uniprotkb:GAG3(gene name synonym)|uniprotkb:NET2(gene name synonym)|uniprotkb:Mitochondria fission 2 protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319748|imex:IM-26944-119 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012962.3|sgd:S000001744|mint:P36130|dip:DIP-5945N|ensemblfungi:YKR036C(gene)|ensemblfungi:YKR036C_mRNA(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016559"(peroxisome fission)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030687"(preribosome, large subunit precursor)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021653|interpro:IPR036322|rcsb pdb:2PQR|ensemblgenomes:YKR036C(identity) refseq:NP_012423.1|sgd:S000003648|dip:DIP-1907N|ensemblfungi:YJL112W(gene)|ensemblfungi:YJL112W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021061|interpro:IPR036322|rcsb pdb:2PQN|rcsb pdb:2XU6|rcsb pdb:3UUX|rcsb pdb:5JST|ensemblgenomes:YJL112W(identity) - crc64:2C6B472CCC2340D3 crc64:CA8A23DBB06193A6 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:vszAMkJRFSZe1PGavlyTsfEcvkI559292 rogid:+OUNA41DE2s5K5VZ1d6F7ZffK+M559292 rigid:t9SmlmP6EYoM87SPwQD1V0h9eqA false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12166 uniprotkb:P06208-1 intact:EBI-37359|uniprotkb:D6W2G7|ensemblfungi:YOR108W intact:EBI-21318961 psi-mi:leu9_yeast(display_long)|uniprotkb:LEU9(gene name)|psi-mi:LEU9(display_short)|uniprotkb:YOR3227w(orf name)|uniprotkb:Alpha-isopropylmalate synthase 2(gene name synonym)|uniprotkb:Alpha-IPM synthase 2(gene name synonym)|uniprotkb:Alpha-isopropylmalate synthase II(gene name synonym)|uniprotkb:YOR108W(locus name) psi-mi:p062081(display_long)|uniprotkb:LEU4(gene name)|psi-mi:LEU4(display_short)|uniprotkb:N2173(orf name)|uniprotkb:YNL104C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319892|imex:IM-26944-657 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014751.1|sgd:S000005634|mint:Q12166|dip:DIP-4153N|ensemblfungi:YOR108W(gene)|ensemblfungi:YOR108W_mRNA(transcript)|go:"GO:0003852"(2-isopropylmalate synthase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0009082"(branched-chain amino acid biosynthetic process)|go:"GO:0009098"(leucine biosynthetic process)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR002034(Alpha-isopropylmalate/homocitrate synthase, conserved site)|interpro:IPR005668(Yeast 2-isopropylmalate synthase)|interpro:IPR013709("2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain")|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR036230|interpro:IPR039371|ensemblgenomes:YOR108W(identity) uniprotkb:P06208-1(isoform-parent)|ensemblgenomes:YNL104C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:xem/K524HzAGsD4IT+y2KU/l7gI559292 rogid:qysUHIGQ5iB9CaOQvK2/+iVHuyQ559292 rigid:iJt24QLrRMwck3tocexJ1sMvl5U false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32798 uniprotkb:P20107 intact:EBI-5006|uniprotkb:D6W314|ensemblfungi:YOR316C intact:EBI-29667|uniprotkb:D6W070|ensemblfungi:YMR243C psi-mi:cot1_yeast(display_long)|uniprotkb:COT1(gene name)|psi-mi:COT1(display_short)|uniprotkb:O6131(orf name)|uniprotkb:YOR316C(locus name) psi-mi:zrc1_yeast(display_long)|uniprotkb:ZRC1(gene name)|psi-mi:ZRC1(display_short)|uniprotkb:YM9408.05C(orf name)|uniprotkb:YMR243C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319880|imex:IM-26944-379 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005843|refseq:NP_014961.3|dip:DIP-7554N|mint:P32798|ensemblfungi:YOR316C(gene)|ensemblfungi:YOR316C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006824"(cobalt ion transport)|go:"GO:0006829"(zinc ion transport)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0015087"(cobalt ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|reactome:R-SCE-425410|ensemblgenomes:YOR316C(identity) refseq:NP_013970.1|sgd:S000004856|dip:DIP-2030N|mint:P20107|ensemblfungi:YMR243C(gene)|ensemblfungi:YMR243C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|reactome:R-SCE-425410|reactome:R-SCE-435368|ensemblgenomes:YMR243C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:HEIg6lhS698E9H3BJeESYAipNwA559292 rogid:ZZlCJ2Xj5Hiumdl3BNStZFS9qM4559292 rigid:4brok8qxir9FTn7Sb3de9BeVDyQ false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12344 uniprotkb:Q04322 intact:EBI-38508|uniprotkb:D6W3C2|ensemblfungi:YPL249C intact:EBI-27427|uniprotkb:D6W016|ensemblfungi:YMR192W psi-mi:gyp5_yeast(display_long)|uniprotkb:GYP5(gene name)|psi-mi:GYP5(display_short)|uniprotkb:YPL249C(locus name) psi-mi:gyl1_yeast(display_long)|uniprotkb:YMR192W(locus name)|uniprotkb:YM9646.04(orf name)|uniprotkb:GYL1(gene name)|psi-mi:GYL1(display_short)|uniprotkb:APP2(gene name synonym)|uniprotkb:GYP5-like protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319868|imex:IM-26944-305 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015075.1|sgd:S000006170|mint:Q12344|dip:DIP-8946N|ensemblfungi:YPL249C(gene)|ensemblfungi:YPL249C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|ensemblgenomes:YPL249C(identity) mint:Q04322|refseq:NP_013917.1|sgd:S000004804|dip:DIP-2891N|ensemblfungi:YMR192W(gene)|ensemblfungi:YMR192W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0017157"(regulation of exocytosis)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|ensemblgenomes:YMR192W(identity) - crc64:67BAAC39B2A51859 - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:oHovDOB1prsJfQnQBfIBxNOFdNw559292 rogid:JXXEUKwB+ysZExb+8We4yeNrftM559292 rigid:o+JsWEIAq0/lN0vmSg5GylNi6nc false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38041 uniprotkb:P38041 intact:EBI-3719|uniprotkb:D6VPR9|ensemblfungi:YBL085W intact:EBI-3719|uniprotkb:D6VPR9|ensemblfungi:YBL085W psi-mi:bob1_yeast(display_long)|uniprotkb:BOI1(gene name)|psi-mi:BOI1(display_short)|uniprotkb:BOB1(gene name synonym)|uniprotkb:YBL085W(locus name)|uniprotkb:YBL0717(orf name)|uniprotkb:GIN7(gene name synonym)|uniprotkb:Growth inhibitory protein 7(gene name synonym)|uniprotkb:BEM1-binding protein(gene name synonym) psi-mi:bob1_yeast(display_long)|uniprotkb:BOI1(gene name)|psi-mi:BOI1(display_short)|uniprotkb:BOB1(gene name synonym)|uniprotkb:YBL085W(locus name)|uniprotkb:YBL0717(orf name)|uniprotkb:GIN7(gene name synonym)|uniprotkb:Growth inhibitory protein 7(gene name synonym)|uniprotkb:BEM1-binding protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319940|imex:IM-26944-307 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009468.1|sgd:S000000181|dip:DIP-2226N|mint:P38041|ensemblfungi:YBL085W(gene)|ensemblfungi:YBL085W_mRNA(transcript)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0001881"(receptor recycling)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007015"(actin filament organization)|go:"GO:0007032"(endosome organization)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0030427"(site of polarized growth)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043332"(mating projection tip)|go:"GO:0055037"(recycling endosome)|interpro:IPR001452(Src homology-3)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR035551|interpro:IPR036028|ensemblgenomes:YBL085W(identity) refseq:NP_009468.1|sgd:S000000181|dip:DIP-2226N|mint:P38041|ensemblfungi:YBL085W(gene)|ensemblfungi:YBL085W_mRNA(transcript)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0001881"(receptor recycling)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005933"(cellular bud)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007015"(actin filament organization)|go:"GO:0007032"(endosome organization)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0030427"(site of polarized growth)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043332"(mating projection tip)|go:"GO:0055037"(recycling endosome)|interpro:IPR001452(Src homology-3)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR035551|interpro:IPR036028|ensemblgenomes:YBL085W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:WcK0gGhMeNGTOtDIXkYjqtOuLl4559292 rogid:WcK0gGhMeNGTOtDIXkYjqtOuLl4559292 rigid:agZjUVQVPK+wjrLwnfB+uiu1nz0 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02969 uniprotkb:Q08580 intact:EBI-37452|uniprotkb:Q6B2A9|uniprotkb:D6W3Q5|ensemblfungi:YPL112C intact:EBI-34476|uniprotkb:D6W2Q2|ensemblfungi:YOR193W psi-mi:pex25_yeast(display_long)|uniprotkb:YPL112C(locus name)|uniprotkb:PEX25(gene name)|psi-mi:PEX25(display_short)|uniprotkb:Peroxin-25(gene name synonym) psi-mi:pex27_yeast(display_long)|uniprotkb:PEX27(gene name)|psi-mi:PEX27(display_short)|uniprotkb:Peroxin-27(gene name synonym)|uniprotkb:YOR193W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319904|imex:IM-26944-129 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000006033|refseq:NP_015213.1|dip:DIP-5292N|mint:Q02969|ensemblfungi:YPL112C(gene)|ensemblfungi:YPL112C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0016559"(peroxisome fission)|go:"GO:0044375"(regulation of peroxisome size)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|ensemblgenomes:YPL112C(identity) sgd:S000005719|mint:Q08580|refseq:NP_014836.3|ensemblfungi:YOR193W(gene)|ensemblfungi:YOR193W_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016559"(peroxisome fission)|go:"GO:0044375"(regulation of peroxisome size)|ensemblgenomes:YOR193W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:42Jce4KR0S5WehK1GVfqhG+Cqbo559292 rogid:4KDjn/JFPYAMsOKZxfT5DiKQWyE559292 rigid:vVnRLT8ibKeBGZj8ce7RgqWxRzI false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38310 uniprotkb:P38310 intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W intact:EBI-20959|uniprotkb:Q9URQ1|uniprotkb:D6VQK4|ensemblfungi:YBR207W psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:fth1_yeast(display_long)|uniprotkb:YBR1446(orf name)|uniprotkb:YBR207W(locus name)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319964|imex:IM-26944-215 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1)|ensemblgenomes:YBR207W(identity) refseq:NP_009766.4|sgd:S000000411|mint:P38310|dip:DIP-4165N|ensemblfungi:YBR207W(gene)|ensemblfungi:YBR207W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR004923(Iron permease FTR1)|ensemblgenomes:YBR207W(identity) - crc64:7B4E620ABC39A053 crc64:7B4E620ABC39A053 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 rogid:I8IlcdwivLRr6CY2IflcYTCdIAc559292 rigid:HSeD7tDZYNbGEOrp/r1ez4UO3fE false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38143 uniprotkb:P38143 intact:EBI-7863|uniprotkb:D6VQP0|ensemblfungi:YBR244W intact:EBI-7863|uniprotkb:D6VQP0|ensemblfungi:YBR244W psi-mi:gpx2_yeast(display_long)|uniprotkb:GPX2(gene name)|psi-mi:GPX2(display_short)|uniprotkb:Glutathione peroxidase homolog 2(gene name synonym)|uniprotkb:YBR1632(orf name)|uniprotkb:YBR244W(locus name) psi-mi:gpx2_yeast(display_long)|uniprotkb:GPX2(gene name)|psi-mi:GPX2(display_short)|uniprotkb:Glutathione peroxidase homolog 2(gene name synonym)|uniprotkb:YBR1632(orf name)|uniprotkb:YBR244W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319976|imex:IM-26944-381 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000448|refseq:NP_009803.3|mint:P38143|dip:DIP-8180N|ensemblfungi:YBR244W(gene)|ensemblfungi:YBR244W_mRNA(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0047066"(phospholipid-hydroperoxide glutathione peroxidase activity)|go:"GO:0051920"(peroxiredoxin activity)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR029759|interpro:IPR029760|interpro:IPR036249|reactome:R-SCE-2142712|reactome:R-SCE-9018676|reactome:R-SCE-9018896|reactome:R-SCE-9020265|reactome:R-SCE-9023661|ensemblgenomes:YBR244W(identity) sgd:S000000448|refseq:NP_009803.3|mint:P38143|dip:DIP-8180N|ensemblfungi:YBR244W(gene)|ensemblfungi:YBR244W_mRNA(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0047066"(phospholipid-hydroperoxide glutathione peroxidase activity)|go:"GO:0051920"(peroxiredoxin activity)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR029759|interpro:IPR029760|interpro:IPR036249|reactome:R-SCE-2142712|reactome:R-SCE-9018676|reactome:R-SCE-9018896|reactome:R-SCE-9020265|reactome:R-SCE-9023661|ensemblgenomes:YBR244W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:cL8rm6IttRi0QYzWVEooubWkZN8559292 rogid:cL8rm6IttRi0QYzWVEooubWkZN8559292 rigid:dYQLHP7pdb0TbhaBrz9vVXurYG4 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38353 uniprotkb:P38353 intact:EBI-18175|uniprotkb:D6VQS8|ensemblfungi:YBR283C intact:EBI-18175|uniprotkb:D6VQS8|ensemblfungi:YBR283C psi-mi:ssh1_yeast(display_long)|uniprotkb:SSH1(gene name)|psi-mi:SSH1(display_short)|uniprotkb:Ssh1 complex subunit alpha(gene name synonym)|uniprotkb:Ssh1 complex subunit SSH1(gene name synonym)|uniprotkb:YBR2020(orf name)|uniprotkb:YBR283C(locus name) psi-mi:ssh1_yeast(display_long)|uniprotkb:SSH1(gene name)|psi-mi:SSH1(display_short)|uniprotkb:Ssh1 complex subunit alpha(gene name synonym)|uniprotkb:Ssh1 complex subunit SSH1(gene name synonym)|uniprotkb:YBR2020(orf name)|uniprotkb:YBR283C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319988|imex:IM-26944-461 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009842.1|sgd:S000000487|ensemblfungi:YBR283C(gene)|ensemblfungi:YBR283C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:2WW9|rcsb pdb:2WWA|dip:DIP-4962N|mint:P38353|ensemblgenomes:YBR283C(identity) refseq:NP_009842.1|sgd:S000000487|ensemblfungi:YBR283C(gene)|ensemblfungi:YBR283C_mRNA(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0043022"(ribosome binding)|go:"GO:0071261"(Ssh1 translocon complex)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|rcsb pdb:2WW9|rcsb pdb:2WWA|dip:DIP-4962N|mint:P38353|ensemblgenomes:YBR283C(identity) - crc64:48267EEA3E0191BD crc64:48267EEA3E0191BD figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:76wvZIdv7W5BQn6wI+sHOGQAyuc559292 rogid:76wvZIdv7W5BQn6wI+sHOGQAyuc559292 rigid:zpd/lbywD1NOxiWad8yUUD2X8hs false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25349 uniprotkb:P25349 intact:EBI-21840|uniprotkb:D6VR14|ensemblfungi:YCR004C intact:EBI-21840|uniprotkb:D6VR14|ensemblfungi:YCR004C psi-mi:ycp4_yeast(display_long)|uniprotkb:YCR042(orf name)|uniprotkb:YCR4C(orf name)|uniprotkb:YCR004C(locus name)|uniprotkb:YCP4(gene name)|psi-mi:YCP4(display_short) psi-mi:ycp4_yeast(display_long)|uniprotkb:YCR042(orf name)|uniprotkb:YCR4C(orf name)|uniprotkb:YCR004C(locus name)|uniprotkb:YCP4(gene name)|psi-mi:YCP4(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320000|imex:IM-26944-133 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009930.1|sgd:S000000597|dip:DIP-1781N|ensemblfungi:YCR004C(gene)|ensemblfungi:YCR004C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|ensemblgenomes:YCR004C(identity) refseq:NP_009930.1|sgd:S000000597|dip:DIP-1781N|ensemblfungi:YCR004C(gene)|ensemblfungi:YCR004C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0045121"(membrane raft)|go:"GO:0071944"(cell periphery)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|ensemblgenomes:YCR004C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:l7d0Z9G9F/3vOnI80MPKdsll1aI559292 rogid:l7d0Z9G9F/3vOnI80MPKdsll1aI559292 rigid:VmidBfDKlOad7vm2b7N9XO53RfA false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03435 uniprotkb:Q03435 intact:EBI-12010|ensemblfungi:YDL002C|uniprotkb:D6VRY6 intact:EBI-12010|ensemblfungi:YDL002C|uniprotkb:D6VRY6 psi-mi:nhp10_yeast(display_long)|uniprotkb:HMO2(gene name synonym)|uniprotkb:YD8119.05C(orf name)|uniprotkb:YDL002C(locus name)|uniprotkb:NHP10(gene name)|psi-mi:NHP10(display_short)|uniprotkb:High mobility group protein 2(gene name synonym) psi-mi:nhp10_yeast(display_long)|uniprotkb:HMO2(gene name synonym)|uniprotkb:YD8119.05C(orf name)|uniprotkb:YDL002C(locus name)|uniprotkb:NHP10(gene name)|psi-mi:NHP10(display_short)|uniprotkb:High mobility group protein 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320012|imex:IM-26944-309 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDL002C(gene)|ensemblfungi:YDL002C_mRNA(transcript)|go:"GO:0000404"(heteroduplex DNA loop binding)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0031011"(Ino80 complex)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0045027"(DNA end binding)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR030483|interpro:IPR036910|reactome:R-SCE-140342|reactome:R-SCE-5620971|reactome:R-SCE-5686938|reactome:R-SCE-6798695|refseq:NP_010282.3|sgd:S000002160|mint:Q03435|dip:DIP-1387N|ensemblgenomes:YDL002C(identity) ensemblfungi:YDL002C(gene)|ensemblfungi:YDL002C_mRNA(transcript)|go:"GO:0000404"(heteroduplex DNA loop binding)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0031011"(Ino80 complex)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0045027"(DNA end binding)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR030483|interpro:IPR036910|reactome:R-SCE-140342|reactome:R-SCE-5620971|reactome:R-SCE-5686938|reactome:R-SCE-6798695|refseq:NP_010282.3|sgd:S000002160|mint:Q03435|dip:DIP-1387N|ensemblgenomes:YDL002C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:d80vaGqvQrja5QSpys5lAbGbZLU559292 rogid:d80vaGqvQrja5QSpys5lAbGbZLU559292 rigid:4M+QMBUotUnTXNStcFK/csQi+YI false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07528 uniprotkb:Q07528 intact:EBI-36894|uniprotkb:D6VRN7|ensemblfungi:YDL113C intact:EBI-36894|uniprotkb:D6VRN7|ensemblfungi:YDL113C psi-mi:atg20_yeast(display_long)|uniprotkb:ATG20(gene name)|psi-mi:ATG20(display_short)|uniprotkb:YDL113C(locus name)|uniprotkb:Cytoplasm to vacuole targeting protein 20(gene name synonym)|uniprotkb:Sorting nexin-42(gene name synonym)|uniprotkb:CVT20(gene name synonym)|uniprotkb:SNX42(gene name synonym) psi-mi:atg20_yeast(display_long)|uniprotkb:ATG20(gene name)|psi-mi:ATG20(display_short)|uniprotkb:YDL113C(locus name)|uniprotkb:Cytoplasm to vacuole targeting protein 20(gene name synonym)|uniprotkb:Sorting nexin-42(gene name synonym)|uniprotkb:CVT20(gene name synonym)|uniprotkb:SNX42(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320024|imex:IM-26944-545 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010170.1|sgd:S000002271|mint:Q07528|dip:DIP-1593N|ensemblfungi:YDL113C(gene)|ensemblfungi:YDL113C_mRNA(transcript)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034498"(early endosome to Golgi transport)|interpro:IPR001683(Phox-like)|interpro:IPR027267|interpro:IPR036871|interpro:IPR044106|ensemblgenomes:YDL113C(identity) refseq:NP_010170.1|sgd:S000002271|mint:Q07528|dip:DIP-1593N|ensemblfungi:YDL113C(gene)|ensemblfungi:YDL113C_mRNA(transcript)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034498"(early endosome to Golgi transport)|interpro:IPR001683(Phox-like)|interpro:IPR027267|interpro:IPR036871|interpro:IPR044106|ensemblgenomes:YDL113C(identity) - crc64:160977A8BECB6D93 crc64:160977A8BECB6D93 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:BWykOKWex5TB/nRzSUOXdZlM8yk559292 rogid:BWykOKWex5TB/nRzSUOXdZlM8yk559292 rigid:EAgNQ+kFK88WGTzoWmI1NAtzjzc false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04344 uniprotkb:Q04344 intact:EBI-8416|uniprotkb:D6VRM5|ensemblfungi:YDL125C intact:EBI-8416|uniprotkb:D6VRM5|ensemblfungi:YDL125C psi-mi:hnt1_yeast(display_long)|uniprotkb:HNT1(gene name)|psi-mi:HNT1(display_short)|uniprotkb:HIT1(gene name synonym)|uniprotkb:Histidine triad nucleotide-binding protein HNT1(gene name synonym)|uniprotkb:Hit family protein 1(gene name synonym)|uniprotkb:YDL125C(locus name) psi-mi:hnt1_yeast(display_long)|uniprotkb:HNT1(gene name)|psi-mi:HNT1(display_short)|uniprotkb:HIT1(gene name synonym)|uniprotkb:Histidine triad nucleotide-binding protein HNT1(gene name synonym)|uniprotkb:Hit family protein 1(gene name synonym)|uniprotkb:YDL125C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320036|imex:IM-26944-463 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010158.1|sgd:S000002283|dip:DIP-2760N|mint:Q04344|ensemblfungi:YDL125C(gene)|ensemblfungi:YDL125C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0010043"(response to zinc ion)|go:"GO:0043530"(adenosine 5'-monophosphoramidase activity)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR001310("Histidine triad (HIT) protein")|interpro:IPR011146(Histidine triad-like motif)|interpro:IPR019808|interpro:IPR036265|interpro:IPR039384|ensemblgenomes:YDL125C(identity) refseq:NP_010158.1|sgd:S000002283|dip:DIP-2760N|mint:Q04344|ensemblfungi:YDL125C(gene)|ensemblfungi:YDL125C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0010043"(response to zinc ion)|go:"GO:0043530"(adenosine 5'-monophosphoramidase activity)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR001310("Histidine triad (HIT) protein")|interpro:IPR011146(Histidine triad-like motif)|interpro:IPR019808|interpro:IPR036265|interpro:IPR039384|ensemblgenomes:YDL125C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:93se/ObwboPzYXLyIpTm7RrKhl0559292 rogid:93se/ObwboPzYXLyIpTm7RrKhl0559292 rigid:Xk4yQSO9F18mB5wPI3oi0WWHiTk false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12176 uniprotkb:Q12176 intact:EBI-10944|ensemblfungi:YDR060W|uniprotkb:D6VS46 intact:EBI-10944|ensemblfungi:YDR060W|uniprotkb:D6VS46 psi-mi:mak21_yeast(display_long)|uniprotkb:MAK21(gene name)|psi-mi:MAK21(display_short)|uniprotkb:YDR060W(locus name)|uniprotkb:D4237(orf name)|uniprotkb:YD9609.14(orf name)|uniprotkb:NOC1(gene name synonym)|uniprotkb:Maintenance of killer protein 21(gene name synonym)|uniprotkb:Nucleolar complex protein 1(gene name synonym) psi-mi:mak21_yeast(display_long)|uniprotkb:MAK21(gene name)|psi-mi:MAK21(display_short)|uniprotkb:YDR060W(locus name)|uniprotkb:D4237(orf name)|uniprotkb:YD9609.14(orf name)|uniprotkb:NOC1(gene name synonym)|uniprotkb:Maintenance of killer protein 21(gene name synonym)|uniprotkb:Nucleolar complex protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320048|imex:IM-26944-661 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDR060W(gene)|ensemblfungi:YDR060W_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030690"(Noc1p-Noc2p complex)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|interpro:IPR005612(CBF)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040155|sgd:S000002467|refseq:NP_010345.3|mint:Q12176|dip:DIP-4040N|ensemblgenomes:YDR060W(identity) ensemblfungi:YDR060W(gene)|ensemblfungi:YDR060W_mRNA(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030690"(Noc1p-Noc2p complex)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|interpro:IPR005612(CBF)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040155|sgd:S000002467|refseq:NP_010345.3|mint:Q12176|dip:DIP-4040N|ensemblgenomes:YDR060W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:Y5IkqRgw551Db48w/pnXZm0AtvQ559292 rogid:Y5IkqRgw551Db48w/pnXZm0AtvQ559292 rigid:n0lqgjd1JeIK9/Egos44TlbjCp4 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P31688 uniprotkb:P31688 intact:EBI-19440|uniprotkb:D6VS60|ensemblfungi:YDR074W intact:EBI-19440|uniprotkb:D6VS60|ensemblfungi:YDR074W psi-mi:tps2_yeast(display_long)|uniprotkb:TPS2(gene name)|psi-mi:TPS2(display_short)|uniprotkb:PFK3(gene name synonym)|uniprotkb:YDR074W(locus name)|uniprotkb:YD8554.07(orf name)|uniprotkb:Trehalose-6-phosphate phosphatase(gene name synonym)|uniprotkb:Trehalose synthase complex catalytic subunit TPS2(gene name synonym) psi-mi:tps2_yeast(display_long)|uniprotkb:TPS2(gene name)|psi-mi:TPS2(display_short)|uniprotkb:PFK3(gene name synonym)|uniprotkb:YDR074W(locus name)|uniprotkb:YD8554.07(orf name)|uniprotkb:Trehalose-6-phosphate phosphatase(gene name synonym)|uniprotkb:Trehalose synthase complex catalytic subunit TPS2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320060|imex:IM-26944-465 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010359.1|sgd:S000002481|ensemblfungi:YDR074W(gene)|ensemblfungi:YDR074W_mRNA(transcript)|go:"GO:0004805"(trehalose-phosphatase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005946"("alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)")|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0070413"(trehalose metabolism in response to stress)|interpro:IPR001830(Glycosyl transferase, family 20)|interpro:IPR003337(Trehalose-phosphatase)|interpro:IPR006379(HAD-superfamily hydrolase, subfamily IIB)|interpro:IPR023214|interpro:IPR036412|dip:DIP-823N|mint:P31688|ensemblgenomes:YDR074W(identity) refseq:NP_010359.1|sgd:S000002481|ensemblfungi:YDR074W(gene)|ensemblfungi:YDR074W_mRNA(transcript)|go:"GO:0004805"(trehalose-phosphatase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005946"("alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)")|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0070413"(trehalose metabolism in response to stress)|interpro:IPR001830(Glycosyl transferase, family 20)|interpro:IPR003337(Trehalose-phosphatase)|interpro:IPR006379(HAD-superfamily hydrolase, subfamily IIB)|interpro:IPR023214|interpro:IPR036412|dip:DIP-823N|mint:P31688|ensemblgenomes:YDR074W(identity) - crc64:E349672CCCDA9349 crc64:E349672CCCDA9349 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:kfEKVrS0+2MOIcLy9XDHbAdFFCI559292 rogid:kfEKVrS0+2MOIcLy9XDHbAdFFCI559292 rigid:HvqvKGkts41UsAoJq1gsV7xfve8 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12449 uniprotkb:Q12449 intact:EBI-37072|uniprotkb:Q02565|uniprotkb:Q7LIE3|uniprotkb:D6VSJ8|ensemblfungi:YDR214W intact:EBI-37072|uniprotkb:Q02565|uniprotkb:Q7LIE3|uniprotkb:D6VSJ8|ensemblfungi:YDR214W psi-mi:aha1_yeast(display_long)|uniprotkb:AHA1(gene name)|psi-mi:AHA1(display_short)|uniprotkb:YDR214W(locus name)|uniprotkb:YD8142.16(orf name)|uniprotkb:YD8142B.06(orf name)|uniprotkb:Activator of Hsp90 ATPase protein 1(gene name synonym) psi-mi:aha1_yeast(display_long)|uniprotkb:AHA1(gene name)|psi-mi:AHA1(display_short)|uniprotkb:YDR214W(locus name)|uniprotkb:YD8142.16(orf name)|uniprotkb:YD8142B.06(orf name)|uniprotkb:Activator of Hsp90 ATPase protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320072|imex:IM-26944-311 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002622|refseq:NP_010500.3|mint:Q12449|dip:DIP-1831N|ensemblfungi:YDR214W(gene)|ensemblfungi:YDR214W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|interpro:IPR013538(Activator of Hsp90 ATPase homologue 1-like)|interpro:IPR015310(Activator of Hsp90 ATPase, N-terminal)|interpro:IPR023393|interpro:IPR036338|interpro:IPR039981|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:6XLB|rcsb pdb:6XLD|rcsb pdb:6XLE|rcsb pdb:6XLF|rcsb pdb:6XLG|rcsb pdb:6XLH|ensemblgenomes:YDR214W(identity) sgd:S000002622|refseq:NP_010500.3|mint:Q12449|dip:DIP-1831N|ensemblfungi:YDR214W(gene)|ensemblfungi:YDR214W_mRNA(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|interpro:IPR013538(Activator of Hsp90 ATPase homologue 1-like)|interpro:IPR015310(Activator of Hsp90 ATPase, N-terminal)|interpro:IPR023393|interpro:IPR036338|interpro:IPR039981|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:6XLB|rcsb pdb:6XLD|rcsb pdb:6XLE|rcsb pdb:6XLF|rcsb pdb:6XLG|rcsb pdb:6XLH|ensemblgenomes:YDR214W(identity) - crc64:06DF6B40EB5050BE crc64:06DF6B40EB5050BE figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:jCVFPwj0+auPVB/BJ/OwlMSBWUM559292 rogid:jCVFPwj0+auPVB/BJ/OwlMSBWUM559292 rigid:N/aS8zY7aXcAuVO2c1QpBD9gp2Y false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05521 uniprotkb:Q05521 intact:EBI-2054360|uniprotkb:D6VSR4|ensemblfungi:YDR284C intact:EBI-2054360|uniprotkb:D6VSR4|ensemblfungi:YDR284C psi-mi:dpp1_yeast(display_long)|uniprotkb:ZRG1(gene name synonym)|uniprotkb:Phosphatidate phosphatase(gene name synonym)|uniprotkb:YDR284C(locus name)|uniprotkb:DPP1(gene name)|psi-mi:DPP1(display_short)|uniprotkb:Lysophosphatidate phosphatase(gene name synonym) psi-mi:dpp1_yeast(display_long)|uniprotkb:ZRG1(gene name synonym)|uniprotkb:Phosphatidate phosphatase(gene name synonym)|uniprotkb:YDR284C(locus name)|uniprotkb:DPP1(gene name)|psi-mi:DPP1(display_short)|uniprotkb:Lysophosphatidate phosphatase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320084|imex:IM-26944-135 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010570.1|sgd:S000002692|dip:DIP-8807N|mint:Q05521|ensemblfungi:YDR284C(gene)|ensemblfungi:YDR284C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000810"(diacylglycerol diphosphate phosphatase activity)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042577"(lipid phosphatase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR036938|interpro:IPR043216|reactome:R-SCE-1660661|reactome:R-SCE-2029485|reactome:R-SCE-419408|ensemblgenomes:YDR284C(identity) refseq:NP_010570.1|sgd:S000002692|dip:DIP-8807N|mint:Q05521|ensemblfungi:YDR284C(gene)|ensemblfungi:YDR284C_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000810"(diacylglycerol diphosphate phosphatase activity)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042577"(lipid phosphatase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR036938|interpro:IPR043216|reactome:R-SCE-1660661|reactome:R-SCE-2029485|reactome:R-SCE-419408|ensemblgenomes:YDR284C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:Hj9zgQNj43XlykGFSKPcXJ28Lqg559292 rogid:Hj9zgQNj43XlykGFSKPcXJ28Lqg559292 rigid:ey0f688vAQwsinujA7MQ/ThW0wM false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02400 uniprotkb:P02400 intact:EBI-15464|uniprotkb:D6VT16|ensemblfungi:YDR382W intact:EBI-15464|uniprotkb:D6VT16|ensemblfungi:YDR382W psi-mi:rla4_yeast(display_long)|uniprotkb:RPP2B(gene name)|psi-mi:RPP2B(display_short)|uniprotkb:L12EIA(gene name synonym)|uniprotkb:RPL45(gene name synonym)|uniprotkb:RPLA4(gene name synonym)|uniprotkb:L12eIA(gene name synonym)|uniprotkb:YP2beta(gene name synonym)|uniprotkb:L45(gene name synonym)|uniprotkb:YL44C(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:YDR382W(locus name)|uniprotkb:Large ribosomal subunit protein P2-B(gene name synonym) psi-mi:rla4_yeast(display_long)|uniprotkb:RPP2B(gene name)|psi-mi:RPP2B(display_short)|uniprotkb:L12EIA(gene name synonym)|uniprotkb:RPL45(gene name synonym)|uniprotkb:RPLA4(gene name synonym)|uniprotkb:L12eIA(gene name synonym)|uniprotkb:YP2beta(gene name synonym)|uniprotkb:L45(gene name synonym)|uniprotkb:YL44C(gene name synonym)|uniprotkb:YPA1(gene name synonym)|uniprotkb:YDR382W(locus name)|uniprotkb:Large ribosomal subunit protein P2-B(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320096|imex:IM-26944-547 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002790|reactome:R-SCE-156827|reactome:R-SCE-1799339|reactome:R-SCE-72689|reactome:R-SCE-72706|reactome:R-SCE-975956|reactome:R-SCE-975957|refseq:NP_010670.3|ensemblfungi:YDR382W(gene)|ensemblfungi:YDR382W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002182"(cytoplasmic translational elongation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0045860"(positive regulation of protein kinase activity)|interpro:IPR027534|interpro:IPR038716|interpro:IPR044076|rcsb pdb:3N2D|rcsb pdb:3N3X|dip:DIP-580N|ensemblgenomes:YDR382W(identity) sgd:S000002790|reactome:R-SCE-156827|reactome:R-SCE-1799339|reactome:R-SCE-72689|reactome:R-SCE-72706|reactome:R-SCE-975956|reactome:R-SCE-975957|refseq:NP_010670.3|ensemblfungi:YDR382W(gene)|ensemblfungi:YDR382W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002182"(cytoplasmic translational elongation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0045860"(positive regulation of protein kinase activity)|interpro:IPR027534|interpro:IPR038716|interpro:IPR044076|rcsb pdb:3N2D|rcsb pdb:3N3X|dip:DIP-580N|ensemblgenomes:YDR382W(identity) - crc64:EC45406CB5F199F4 crc64:EC45406CB5F199F4 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:dvY8zJb/i5nIRnNekgTQdY9Novs559292 rogid:dvY8zJb/i5nIRnNekgTQdY9Novs559292 rigid:uyqeJppclrYQktOv/K5o9EP1c7Q false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04178 uniprotkb:Q04178 intact:EBI-29727|uniprotkb:D6VT32|ensemblfungi:YDR399W intact:EBI-29727|uniprotkb:D6VT32|ensemblfungi:YDR399W psi-mi:hprt_yeast(display_long)|uniprotkb:BRA6(gene name synonym)|uniprotkb:YDR399W(locus name)|uniprotkb:Bypass of repression by adenine protein 6(gene name synonym)|uniprotkb:HPT1(gene name)|psi-mi:HPT1(display_short)|uniprotkb:D9509.18(orf name) psi-mi:hprt_yeast(display_long)|uniprotkb:BRA6(gene name synonym)|uniprotkb:YDR399W(locus name)|uniprotkb:Bypass of repression by adenine protein 6(gene name synonym)|uniprotkb:HPT1(gene name)|psi-mi:HPT1(display_short)|uniprotkb:D9509.18(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320108|imex:IM-26944-383 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002807|refseq:NP_010687.3|dip:DIP-4318N|ensemblfungi:YDR399W(gene)|ensemblfungi:YDR399W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0004422"(hypoxanthine phosphoribosyltransferase activity)|go:"GO:0004615"(phosphomannomutase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0032263"(GMP salvage)|go:"GO:0032264"(IMP salvage)|go:"GO:0032265"(XMP salvage)|go:"GO:0046100"(hypoxanthine metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0052657"(guanine phosphoribosyltransferase activity)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR029057|rcsb pdb:2JKY|rcsb pdb:2JKZ|rcsb pdb:2XBU|ensemblgenomes:YDR399W(identity) sgd:S000002807|refseq:NP_010687.3|dip:DIP-4318N|ensemblfungi:YDR399W(gene)|ensemblfungi:YDR399W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0004422"(hypoxanthine phosphoribosyltransferase activity)|go:"GO:0004615"(phosphomannomutase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0032263"(GMP salvage)|go:"GO:0032264"(IMP salvage)|go:"GO:0032265"(XMP salvage)|go:"GO:0046100"(hypoxanthine metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0052657"(guanine phosphoribosyltransferase activity)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR029057|rcsb pdb:2JKY|rcsb pdb:2JKZ|rcsb pdb:2XBU|ensemblgenomes:YDR399W(identity) - crc64:0D18A02BAF8F5390 crc64:0D18A02BAF8F5390 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:5WavMdg6hpLH/ODtat1kRkPknSk559292 rogid:5WavMdg6hpLH/ODtat1kRkPknSk559292 rigid:fXR0L4ricr+dGc8/7VAPPMBIQgI false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P56508 uniprotkb:P56508 intact:EBI-22135|uniprotkb:D6VTE7|ensemblfungi:YDR525W-A intact:EBI-22135|uniprotkb:D6VTE7|ensemblfungi:YDR525W-A psi-mi:sna2_yeast(display_long)|uniprotkb:YDR525BW(orf name)|uniprotkb:YDR525W-A(locus name)|uniprotkb:SNA2(gene name)|psi-mi:SNA2(display_short) psi-mi:sna2_yeast(display_long)|uniprotkb:YDR525BW(orf name)|uniprotkb:YDR525W-A(locus name)|uniprotkb:SNA2(gene name)|psi-mi:SNA2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320120|imex:IM-26944-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010814.1|sgd:S000007236|interpro:IPR000612(Protein of unknown function UPF0057)|ensemblfungi:YDR525W-A(gene)|ensemblfungi:YDR525W-A_mRNA(transcript)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|ensemblgenomes:YDR525W-A(identity) refseq:NP_010814.1|sgd:S000007236|interpro:IPR000612(Protein of unknown function UPF0057)|ensemblfungi:YDR525W-A(gene)|ensemblfungi:YDR525W-A_mRNA(transcript)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|ensemblgenomes:YDR525W-A(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:zqjXp3iXSEELPlEPJCNgQgsCr+o559292 rogid:zqjXp3iXSEELPlEPJCNgQgsCr+o559292 rigid:TZ8TJIVpKGE0FYJ9v/lETKxq6vc false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40002 uniprotkb:P40002 intact:EBI-22284|uniprotkb:D3DLP0|ensemblfungi:YEL007W intact:EBI-22284|uniprotkb:D3DLP0|ensemblfungi:YEL007W psi-mi:mit1_yeast(display_long)|uniprotkb:MIT1(gene name)|psi-mi:MIT1(display_short)|uniprotkb:YEL007W(locus name) psi-mi:mit1_yeast(display_long)|uniprotkb:MIT1(gene name)|psi-mi:MIT1(display_short)|uniprotkb:YEL007W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320132|imex:IM-26944-137 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000733|interpro:IPR018608|refseq:NP_010909.1|ensemblfungi:YEL007W(gene)|ensemblfungi:YEL007W_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|ensemblgenomes:YEL007W(identity) sgd:S000000733|interpro:IPR018608|refseq:NP_010909.1|ensemblfungi:YEL007W(gene)|ensemblfungi:YEL007W_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|ensemblgenomes:YEL007W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:mEFDva2f4e8fDG+b0Ydo7tXmUIg559292 rogid:mEFDva2f4e8fDG+b0Ydo7tXmUIg559292 rigid:rPBKkvGuceAcLUjtyf1AzurFF18 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39727 uniprotkb:P39727 intact:EBI-20659|uniprotkb:D6VPH4|ensemblfungi:YAL042W intact:EBI-20659|uniprotkb:D6VPH4|ensemblfungi:YAL042W psi-mi:erv46_yeast(display_long)|uniprotkb:FUN9(orf name)|uniprotkb:YAL042W(locus name)|uniprotkb:ERV46(gene name)|psi-mi:ERV46(display_short) psi-mi:erv46_yeast(display_long)|uniprotkb:FUN9(orf name)|uniprotkb:YAL042W(locus name)|uniprotkb:ERV46(gene name)|psi-mi:ERV46(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319928|imex:IM-26944-131 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009358.1|sgd:S000000040|ensemblfungi:YAL042W(gene)|ensemblfungi:YAL042W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542|dip:DIP-3792N|mint:P39727|ensemblgenomes:YAL042W(identity) refseq:NP_009358.1|sgd:S000000040|ensemblfungi:YAL042W(gene)|ensemblfungi:YAL042W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542|dip:DIP-3792N|mint:P39727|ensemblgenomes:YAL042W(identity) - crc64:FB7BC171B88BB5EA crc64:FB7BC171B88BB5EA figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:tVyaLk7odK7bfnaz1FMv0E9lgtU559292 rogid:tVyaLk7odK7bfnaz1FMv0E9lgtU559292 rigid:1gqABSAoO+3hdk4fqw83M2n0xRs false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P24784 uniprotkb:P06634 intact:EBI-5596|uniprotkb:P20446|uniprotkb:D6W3P9|ensemblfungi:YPL119C intact:EBI-5744|uniprotkb:D6W2R0|ensemblfungi:YOR204W psi-mi:dbp1_yeast(display_long)|uniprotkb:DBP1(gene name)|psi-mi:DBP1(display_short)|uniprotkb:YPL119C(locus name)|uniprotkb:LPH8C(orf name)|uniprotkb:DEAD box protein 1(gene name synonym)|uniprotkb:Helicase CA1(gene name synonym) psi-mi:ded1_yeast(display_long)|uniprotkb:DED1(gene name)|psi-mi:DED1(display_short)|uniprotkb:SPP81(gene name synonym)|uniprotkb:YOR204W(locus name)|uniprotkb:DEAD box protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319916|imex:IM-26944-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015206.1|sgd:S000006040|dip:DIP-2576N|mint:P24784|ensemblfungi:YPL119C(gene)|ensemblfungi:YPL119C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044763|ensemblgenomes:YPL119C(identity) sgd:S000005730|refseq:NP_014847.3|dip:DIP-5820N|mint:P06634|ensemblfungi:YOR204W(gene)|ensemblfungi:YOR204W_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044763|reactome:R-SCE-6798695|ensemblgenomes:YOR204W(identity) - - crc64:B6722D94C03BFA4B figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:8TFwSQq3dopTasOH0G/KZ12DDGE559292 rogid:FkldumX6m5gBuuaG09aTJ0kuMZM559292 rigid:ViW4daqDyjZldSTusJ5qfTWmLYs false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P00817 uniprotkb:P00817 intact:EBI-9338|ensemblfungi:YBR011C|uniprotkb:D6VQ12 intact:EBI-9338|ensemblfungi:YBR011C|uniprotkb:D6VQ12 psi-mi:ipyr_yeast(display_long)|uniprotkb:IPP1(gene name)|psi-mi:IPP1(display_short)|uniprotkb:PPA(gene name synonym)|uniprotkb:PPA1(gene name synonym)|uniprotkb:YBR011C(locus name)|uniprotkb:YBR0202(orf name)|uniprotkb:Pyrophosphate phospho-hydrolase(gene name synonym) psi-mi:ipyr_yeast(display_long)|uniprotkb:IPP1(gene name)|psi-mi:IPP1(display_short)|uniprotkb:PPA(gene name synonym)|uniprotkb:PPA1(gene name synonym)|uniprotkb:YBR011C(locus name)|uniprotkb:YBR0202(orf name)|uniprotkb:Pyrophosphate phospho-hydrolase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21319952|imex:IM-26944-659 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004427"(inorganic diphosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006796"(phosphate-containing compound metabolic process)|ensemblfungi:YBR011C(gene)|interpro:IPR008162(Inorganic pyrophosphatase)|ensemblfungi:YBR011C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|interpro:IPR036649|rcsb pdb:117E|rcsb pdb:1E6A|rcsb pdb:1E9G|rcsb pdb:1HUJ|rcsb pdb:1HUK|rcsb pdb:1M38|rcsb pdb:1PYP|rcsb pdb:1WGI|rcsb pdb:1WGJ|rcsb pdb:1YPP|rcsb pdb:2IHP|rcsb pdb:2IK0|rcsb pdb:2IK1|rcsb pdb:2IK2|rcsb pdb:2IK4|rcsb pdb:2IK6|rcsb pdb:2IK7|rcsb pdb:2IK9|reactome:R-SCE-379716|reactome:R-SCE-379726|reactome:R-SCE-71737|rcsb pdb:8PRK|refseq:NP_009565.1|sgd:S000000215|dip:DIP-5753N|mint:P00817|ensemblgenomes:YBR011C(identity) go:"GO:0004427"(inorganic diphosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006796"(phosphate-containing compound metabolic process)|ensemblfungi:YBR011C(gene)|interpro:IPR008162(Inorganic pyrophosphatase)|ensemblfungi:YBR011C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|interpro:IPR036649|rcsb pdb:117E|rcsb pdb:1E6A|rcsb pdb:1E9G|rcsb pdb:1HUJ|rcsb pdb:1HUK|rcsb pdb:1M38|rcsb pdb:1PYP|rcsb pdb:1WGI|rcsb pdb:1WGJ|rcsb pdb:1YPP|rcsb pdb:2IHP|rcsb pdb:2IK0|rcsb pdb:2IK1|rcsb pdb:2IK2|rcsb pdb:2IK4|rcsb pdb:2IK6|rcsb pdb:2IK7|rcsb pdb:2IK9|reactome:R-SCE-379716|reactome:R-SCE-379726|reactome:R-SCE-71737|rcsb pdb:8PRK|refseq:NP_009565.1|sgd:S000000215|dip:DIP-5753N|mint:P00817|ensemblgenomes:YBR011C(identity) - crc64:1DC19A702A389BA9 crc64:1DC19A702A389BA9 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:ze8BQA6+oCsMJY9DFbVdukBCliY559292 rogid:ze8BQA6+oCsMJY9DFbVdukBCliY559292 rigid:Ogr0gQT0h09EIyyepEZE0JTqo/g false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53235 uniprotkb:P53235 intact:EBI-23172|uniprotkb:D6VUI9|uniprotkb:Q45U32|ensemblfungi:YGR054W intact:EBI-23172|uniprotkb:D6VUI9|uniprotkb:Q45U32|ensemblfungi:YGR054W psi-mi:eif2a_yeast(display_long)|uniprotkb:YGR054W(locus name) psi-mi:eif2a_yeast(display_long)|uniprotkb:YGR054W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320228|imex:IM-26944-549 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003286|refseq:NP_011568.3|dip:DIP-5518N|mint:P53235|ensemblfungi:YGR054W(gene)|ensemblfungi:YGR054W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0006413"(translational initiation)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|interpro:IPR011387(Translation initiation factor eIF-2A)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|ensemblgenomes:YGR054W(identity) sgd:S000003286|refseq:NP_011568.3|dip:DIP-5518N|mint:P53235|ensemblfungi:YGR054W(gene)|ensemblfungi:YGR054W_mRNA(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0006413"(translational initiation)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|interpro:IPR011387(Translation initiation factor eIF-2A)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|ensemblgenomes:YGR054W(identity) - crc64:F3C2E78504D83418 crc64:F3C2E78504D83418 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:x8zDCH5W5GusC7qYd0mDATXhGVI559292 rogid:x8zDCH5W5GusC7qYd0mDATXhGVI559292 rigid:RwT8pEFBNX7TDjSPular29DC5TE false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53223 uniprotkb:P53223 intact:EBI-23136|uniprotkb:D6VUH3|uniprotkb:Q45U47|ensemblfungi:YGR036C intact:EBI-23136|uniprotkb:D6VUH3|uniprotkb:Q45U47|ensemblfungi:YGR036C psi-mi:cax4_yeast(display_long)|uniprotkb:CAX4(gene name)|psi-mi:CAX4(display_short)|uniprotkb:CWH8(gene name synonym)|uniprotkb:Dolichyl pyrophosphate phosphatase(gene name synonym)|uniprotkb:YGR036C(locus name) psi-mi:cax4_yeast(display_long)|uniprotkb:CAX4(gene name)|psi-mi:CAX4(display_short)|uniprotkb:CWH8(gene name synonym)|uniprotkb:Dolichyl pyrophosphate phosphatase(gene name synonym)|uniprotkb:YGR036C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320216|imex:IM-26944-385 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003268|refseq:NP_011550.3|dip:DIP-5237N|mint:P53223|ensemblfungi:YGR036C(gene)|ensemblfungi:YGR036C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0047874"(dolichyldiphosphatase activity)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR036938|interpro:IPR039666|interpro:IPR039667|reactome:R-SCE-446199|ensemblgenomes:YGR036C(identity) sgd:S000003268|refseq:NP_011550.3|dip:DIP-5237N|mint:P53223|ensemblfungi:YGR036C(gene)|ensemblfungi:YGR036C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0047874"(dolichyldiphosphatase activity)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR036938|interpro:IPR039666|interpro:IPR039667|reactome:R-SCE-446199|ensemblgenomes:YGR036C(identity) - crc64:C8EC49CBFC08F8F8 crc64:C8EC49CBFC08F8F8 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:qhGZMd77fH1ChaW9F7B1Uxvf2M0559292 rogid:qhGZMd77fH1ChaW9F7B1Uxvf2M0559292 rigid:O9bAkTIza0DREqZ35yzftIQFOoo false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P07270 uniprotkb:P07270 intact:EBI-13378|uniprotkb:D6VTR7|ensemblfungi:YFR034C intact:EBI-13378|uniprotkb:D6VTR7|ensemblfungi:YFR034C psi-mi:pho4_yeast(display_long)|uniprotkb:PHO4(gene name)|psi-mi:PHO4(display_short)|uniprotkb:YFR034C(locus name) psi-mi:pho4_yeast(display_long)|uniprotkb:PHO4(gene name)|psi-mi:PHO4(display_short)|uniprotkb:YFR034C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320192|imex:IM-26944-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116692.1|sgd:S000001930|mint:P07270|dip:DIP-911N|ensemblfungi:YFR034C(gene)|ensemblfungi:YFR034C_mRNA(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016036"(cellular response to phosphate starvation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045937"(positive regulation of phosphate metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|rcsb pdb:1A0A|rcsb pdb:3W3X|ensemblgenomes:YFR034C(identity) refseq:NP_116692.1|sgd:S000001930|mint:P07270|dip:DIP-911N|ensemblfungi:YFR034C(gene)|ensemblfungi:YFR034C_mRNA(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016036"(cellular response to phosphate starvation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045937"(positive regulation of phosphate metabolic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|rcsb pdb:1A0A|rcsb pdb:3W3X|ensemblgenomes:YFR034C(identity) - crc64:6DB93C0DDDB4D741 crc64:6DB93C0DDDB4D741 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:OSNR+Irg2GrmxUdcBubYnrmHeKs559292 rogid:OSNR+Irg2GrmxUdcBubYnrmHeKs559292 rigid:0dkFvxBHnRlRS3l6Fy1a9ZVcywk false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43549 uniprotkb:P43549 intact:EBI-22863|uniprotkb:D6VTH6|ensemblfungi:YFL054C intact:EBI-22863|uniprotkb:D6VTH6|ensemblfungi:YFL054C psi-mi:aqy3_yeast(display_long)|uniprotkb:AQY3(gene name)|psi-mi:AQY3(display_short)|uniprotkb:Aquaporin-3(gene name synonym)|uniprotkb:YFL054C(locus name) psi-mi:aqy3_yeast(display_long)|uniprotkb:AQY3(gene name)|psi-mi:AQY3(display_short)|uniprotkb:Aquaporin-3(gene name synonym)|uniprotkb:YFL054C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320180|imex:IM-26944-313 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116601.1|sgd:S000001840|dip:DIP-4535N|mint:P43549|ensemblfungi:YFL054C(gene)|ensemblfungi:YFL054C_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015254"(glycerol channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR000425(Major intrinsic protein)|interpro:IPR022357|interpro:IPR023271|reactome:R-SCE-432030|reactome:R-SCE-432040|reactome:R-SCE-432047|ensemblgenomes:YFL054C(identity) refseq:NP_116601.1|sgd:S000001840|dip:DIP-4535N|mint:P43549|ensemblfungi:YFL054C(gene)|ensemblfungi:YFL054C_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015254"(glycerol channel activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR000425(Major intrinsic protein)|interpro:IPR022357|interpro:IPR023271|reactome:R-SCE-432030|reactome:R-SCE-432040|reactome:R-SCE-432047|ensemblgenomes:YFL054C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:7t5DbPLgmrxCzOvlCqMCUjjKHms559292 rogid:7t5DbPLgmrxCzOvlCqMCUjjKHms559292 rigid:SKVv7Z8G1lKQZQr1HJg/hDmadU8 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32660 uniprotkb:P32660 intact:EBI-3121|uniprotkb:D3DM74|ensemblfungi:YER166W intact:EBI-3121|uniprotkb:D3DM74|ensemblfungi:YER166W psi-mi:atc5_yeast(display_long)|uniprotkb:DNF1(gene name)|psi-mi:DNF1(display_short)|uniprotkb:YER166W(locus name)|uniprotkb:SYGP-ORF7(orf name)|uniprotkb:Flippase DNF1(gene name synonym) psi-mi:atc5_yeast(display_long)|uniprotkb:DNF1(gene name)|psi-mi:DNF1(display_short)|uniprotkb:YER166W(locus name)|uniprotkb:SYGP-ORF7(orf name)|uniprotkb:Flippase DNF1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320168|imex:IM-26944-467 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000968|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR026871|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:7KY6|rcsb pdb:7KYB|rcsb pdb:7KYC|refseq:NP_011093.3|dip:DIP-7949N|mint:P32660|ensemblfungi:YER166W(gene)|ensemblfungi:YER166W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|ensemblgenomes:YER166W(identity) sgd:S000000968|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR026871|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:7KY6|rcsb pdb:7KYB|rcsb pdb:7KYC|refseq:NP_011093.3|dip:DIP-7949N|mint:P32660|ensemblfungi:YER166W(gene)|ensemblfungi:YER166W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|ensemblgenomes:YER166W(identity) - crc64:3CC3FBA8ADDE8960 crc64:3CC3FBA8ADDE8960 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:4ciEaV0aGjDqtpexkFJ0l737SpA559292 rogid:4ciEaV0aGjDqtpexkFJ0l737SpA559292 rigid:fZ/KnLPKO/KfwbZaF2tBUbEUOV0 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40071 uniprotkb:P40071 intact:EBI-22657|uniprotkb:D3DM19|ensemblfungi:YER113C intact:EBI-22657|uniprotkb:D3DM19|ensemblfungi:YER113C psi-mi:tmn3_yeast(display_long)|uniprotkb:YER113C(locus name)|uniprotkb:TMN3(gene name)|psi-mi:TMN3(display_short) psi-mi:tmn3_yeast(display_long)|uniprotkb:YER113C(locus name)|uniprotkb:TMN3(gene name)|psi-mi:TMN3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320156|imex:IM-26944-217 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011038.3|sgd:S000000915|dip:DIP-849N|mint:P40071|ensemblfungi:YER113C(gene)|ensemblfungi:YER113C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006811"(ion transport)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0072657"(protein localization to membrane)|interpro:IPR004240("Nonaspanin (TM9SF)")|ensemblgenomes:YER113C(identity) refseq:NP_011038.3|sgd:S000000915|dip:DIP-849N|mint:P40071|ensemblfungi:YER113C(gene)|ensemblfungi:YER113C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006811"(ion transport)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0072657"(protein localization to membrane)|interpro:IPR004240("Nonaspanin (TM9SF)")|ensemblgenomes:YER113C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:8BxN4sGvO60kSO6ApFWZmiaQjAI559292 rogid:8BxN4sGvO60kSO6ApFWZmiaQjAI559292 rigid:5KoKz1M0nCT6/byFtTjOfpXCAOA false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39979 uniprotkb:P39979 intact:EBI-22400|uniprotkb:D3DLI4 intact:EBI-22400|uniprotkb:D3DLI4 psi-mi:hpa3_yeast(display_long)|uniprotkb:HPA3(gene name)|psi-mi:HPA3(display_short)|uniprotkb:Histone and other protein acetyltransferase 3(gene name synonym)|uniprotkb:YEL066W(locus name) psi-mi:hpa3_yeast(display_long)|uniprotkb:HPA3(gene name)|psi-mi:HPA3(display_short)|uniprotkb:Histone and other protein acetyltransferase 3(gene name synonym)|uniprotkb:YEL066W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320144|imex:IM-26944-663 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010848.1|sgd:S000000792|dip:DIP-2063N|reactome:R-SCE-351200|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006473"(protein acetylation)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0046416"(D-amino acid metabolic process)|go:"GO:0047812"(D-amino-acid N-acetyltransferase activity)|go:"GO:0070458"(cellular detoxification of nitrogen compound)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR032962|ensemblgenomes:YEL066W(identity) refseq:NP_010848.1|sgd:S000000792|dip:DIP-2063N|reactome:R-SCE-351200|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006473"(protein acetylation)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0046416"(D-amino acid metabolic process)|go:"GO:0047812"(D-amino-acid N-acetyltransferase activity)|go:"GO:0070458"(cellular detoxification of nitrogen compound)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR032962|ensemblgenomes:YEL066W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:xwuUua7JEGxbR+nQiKA9SHDDj6g559292 rogid:xwuUua7JEGxbR+nQiKA9SHDDj6g559292 rigid:RaJAbckIfoEGwOjKOpLuc1FJSFg false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40260 uniprotkb:P40260 intact:EBI-10714|ensemblfungi:YGR121C|uniprotkb:D6VUQ2 intact:EBI-10714|ensemblfungi:YGR121C|uniprotkb:D6VUQ2 psi-mi:mep1_yeast(display_long)|uniprotkb:MEP1(gene name)|psi-mi:MEP1(display_short)|uniprotkb:YGR121C(locus name)|uniprotkb:G6331(orf name)|uniprotkb:AMT1(gene name synonym) psi-mi:mep1_yeast(display_long)|uniprotkb:MEP1(gene name)|psi-mi:MEP1(display_short)|uniprotkb:YGR121C(locus name)|uniprotkb:G6331(orf name)|uniprotkb:AMT1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320240|imex:IM-26944-469 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR121C(gene)|ensemblfungi:YGR121C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|sgd:S000003353|refseq:NP_011636.3|mint:P40260|dip:DIP-5530N|ensemblgenomes:YGR121C(identity) ensemblfungi:YGR121C(gene)|ensemblfungi:YGR121C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|sgd:S000003353|refseq:NP_011636.3|mint:P40260|dip:DIP-5530N|ensemblgenomes:YGR121C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:VnoBl5jhQD24N0SbCLv68HCwl1U559292 rogid:VnoBl5jhQD24N0SbCLv68HCwl1U559292 rigid:zGJ3NHQkvmYeYIDPX6Oxhs5ln1Q false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53278 uniprotkb:P53278 intact:EBI-23314|uniprotkb:D6VUR2|ensemblfungi:YGR130C intact:EBI-23314|uniprotkb:D6VUR2|ensemblfungi:YGR130C psi-mi:yg3a_yeast(display_long)|uniprotkb:YGR130C(locus name) psi-mi:yg3a_yeast(display_long)|uniprotkb:YGR130C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320252|imex:IM-26944-315 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011646.1|sgd:S000003362|dip:DIP-3006N|mint:P53278|ensemblfungi:YGR130C(gene)|ensemblfungi:YGR130C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0032126"(eisosome)|ensemblgenomes:YGR130C(identity) refseq:NP_011646.1|sgd:S000003362|dip:DIP-3006N|mint:P53278|ensemblfungi:YGR130C(gene)|ensemblfungi:YGR130C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0032126"(eisosome)|ensemblgenomes:YGR130C(identity) - crc64:D482327C9274C026 crc64:D482327C9274C026 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:iTa1C3VXvI8QteEEgkfjQDp9gvY559292 rogid:iTa1C3VXvI8QteEEgkfjQDp9gvY559292 rigid:NxdzgWawk40FWc2Aw5EIb6UXiIE false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53290 uniprotkb:P53290 intact:EBI-7962|uniprotkb:D6VUU7|ensemblfungi:YGR163W intact:EBI-7962|uniprotkb:D6VUU7|ensemblfungi:YGR163W psi-mi:gtr2_yeast(display_long)|uniprotkb:YGR163W(locus name)|uniprotkb:GTR2(gene name)|psi-mi:GTR2(display_short) psi-mi:gtr2_yeast(display_long)|uniprotkb:YGR163W(locus name)|uniprotkb:GTR2(gene name)|psi-mi:GTR2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320264|imex:IM-26944-551 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003395|refseq:NP_011679.3|mint:P53290|dip:DIP-4521N|ensemblfungi:YGR163W(gene)|ensemblfungi:YGR163W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000785"(chromatin)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990131"(Gtr1-Gtr2 GTPase complex)|interpro:IPR006762(Gtr1/RagA G protein)|interpro:IPR027417|interpro:IPR039400|rcsb pdb:3R7W|rcsb pdb:4ARZ|rcsb pdb:6JWP|reactome:R-SCE-165159|reactome:R-SCE-9639288|ensemblgenomes:YGR163W(identity) sgd:S000003395|refseq:NP_011679.3|mint:P53290|dip:DIP-4521N|ensemblfungi:YGR163W(gene)|ensemblfungi:YGR163W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000785"(chromatin)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0016237"(lysosomal microautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990131"(Gtr1-Gtr2 GTPase complex)|interpro:IPR006762(Gtr1/RagA G protein)|interpro:IPR027417|interpro:IPR039400|rcsb pdb:3R7W|rcsb pdb:4ARZ|rcsb pdb:6JWP|reactome:R-SCE-165159|reactome:R-SCE-9639288|ensemblgenomes:YGR163W(identity) - crc64:0A0D16C81F73184D crc64:0A0D16C81F73184D figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:+b9bPvzin/YUc5fOZZVCcFu/GEM559292 rogid:+b9bPvzin/YUc5fOZZVCcFu/GEM559292 rigid:WJ1KpWgG4en4GY88ClJavXtKQDQ false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P16861 uniprotkb:P16861 intact:EBI-9428|ensemblfungi:YGR240C|uniprotkb:D6VV20 intact:EBI-9428|ensemblfungi:YGR240C|uniprotkb:D6VV20 psi-mi:pfka1_yeast(display_long)|uniprotkb:PFK1(gene name)|psi-mi:PFK1(display_short)|uniprotkb:YGR240C(locus name)|uniprotkb:G8599(orf name)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:ATP-dependent 6-phosphofructokinase(gene name synonym) psi-mi:pfka1_yeast(display_long)|uniprotkb:PFK1(gene name)|psi-mi:PFK1(display_short)|uniprotkb:YGR240C(locus name)|uniprotkb:G8599(orf name)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:ATP-dependent 6-phosphofructokinase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320276|imex:IM-26944-219 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011756.1|sgd:S000003472|ensemblfungi:YGR240C(gene)|ensemblfungi:YGR240C_mRNA(transcript)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005945"(6-phosphofructokinase complex)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0016208"(AMP binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070095"(fructose-6-phosphate binding)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000023(Phosphofructokinase)|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR022953|interpro:IPR035966|interpro:IPR040712|rcsb pdb:3O8O|reactome:R-SCE-6798695|reactome:R-SCE-70171|mint:P16861|dip:DIP-1505N|ensemblgenomes:YGR240C(identity) refseq:NP_011756.1|sgd:S000003472|ensemblfungi:YGR240C(gene)|ensemblfungi:YGR240C_mRNA(transcript)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005945"(6-phosphofructokinase complex)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0016208"(AMP binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070095"(fructose-6-phosphate binding)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000023(Phosphofructokinase)|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR022953|interpro:IPR035966|interpro:IPR040712|rcsb pdb:3O8O|reactome:R-SCE-6798695|reactome:R-SCE-70171|mint:P16861|dip:DIP-1505N|ensemblgenomes:YGR240C(identity) - crc64:995B3DF7C7781B29 crc64:995B3DF7C7781B29 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:mqqXE8Cvcp019pDQsU01zBYUsCc559292 rogid:mqqXE8Cvcp019pDQsU01zBYUsCc559292 rigid:w4jPF6OhTW6l7ZOPk9MBpxe4hpA false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47072 uniprotkb:P47072 intact:EBI-25803|uniprotkb:D6VWG2|uniprotkb:P47071|uniprotkb:Q86ZR5|ensemblfungi:YJL016W intact:EBI-25803|uniprotkb:D6VWG2|uniprotkb:P47071|uniprotkb:Q86ZR5|ensemblfungi:YJL016W psi-mi:yjb6_yeast(display_long)|uniprotkb:J1320(orf name)|uniprotkb:J1326(orf name)|uniprotkb:YJL017W(orf name)|uniprotkb:YJL016W(locus name) psi-mi:yjb6_yeast(display_long)|uniprotkb:J1320(orf name)|uniprotkb:J1326(orf name)|uniprotkb:YJL017W(orf name)|uniprotkb:YJL016W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320288|imex:IM-26944-553 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003553|refseq:NP_012518.2|mint:P47072|dip:DIP-4907N|ensemblfungi:YJL016W(gene)|ensemblfungi:YJL016W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|ensemblgenomes:YJL016W(identity) sgd:S000003553|refseq:NP_012518.2|mint:P47072|dip:DIP-4907N|ensemblfungi:YJL016W(gene)|ensemblfungi:YJL016W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|ensemblgenomes:YJL016W(identity) - crc64:21D1541BCFEFDFF6 crc64:21D1541BCFEFDFF6 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:XRf3g3pILUK7J16Tol90s1MoEY4559292 rogid:XRf3g3pILUK7J16Tol90s1MoEY4559292 rigid:rxMoOeboVfcwEtyOh+sdSyNWzMQ false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34163 uniprotkb:P34163 intact:EBI-19177|uniprotkb:D6VX56|ensemblfungi:YKL140W intact:EBI-19177|uniprotkb:D6VX56|ensemblfungi:YKL140W psi-mi:tgl1_yeast(display_long)|uniprotkb:TGL1(gene name)|psi-mi:TGL1(display_short)|uniprotkb:YKL140W(locus name)|uniprotkb:YKL5(orf name)|uniprotkb:Triglyceride lipase-cholesterol esterase 1(gene name synonym) psi-mi:tgl1_yeast(display_long)|uniprotkb:TGL1(gene name)|psi-mi:TGL1(display_short)|uniprotkb:YKL140W(locus name)|uniprotkb:YKL5(orf name)|uniprotkb:Triglyceride lipase-cholesterol esterase 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320300|imex:IM-26944-317 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012782.1|sgd:S000001623|ensemblfungi:YKL140W(gene)|ensemblfungi:YKL140W_mRNA(transcript)|go:"GO:0004771"(sterol esterase activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0044255"(cellular lipid metabolic process)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR029058|dip:DIP-6306N|mint:P34163|ensemblgenomes:YKL140W(identity) refseq:NP_012782.1|sgd:S000001623|ensemblfungi:YKL140W(gene)|ensemblfungi:YKL140W_mRNA(transcript)|go:"GO:0004771"(sterol esterase activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0044255"(cellular lipid metabolic process)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR029058|dip:DIP-6306N|mint:P34163|ensemblgenomes:YKL140W(identity) - crc64:32D1F230701CB083 crc64:32D1F230701CB083 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:/f3560MDciadPqvZ0iY9e9oVBH8559292 rogid:/f3560MDciadPqvZ0iY9e9oVBH8559292 rigid:dMAZdSMp7V20SbTxBSsfK7TqDUE false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P13134 uniprotkb:P13134 intact:EBI-9658|ensemblfungi:YNL238W|uniprotkb:D6W0V5 intact:EBI-9658|ensemblfungi:YNL238W|uniprotkb:D6W0V5 psi-mi:kex2_yeast(display_long)|uniprotkb:KEX2(gene name)|psi-mi:KEX2(display_short)|uniprotkb:QDS1(gene name synonym)|uniprotkb:YNL238W(locus name)|uniprotkb:N1122(orf name)|uniprotkb:Protease KEX2(gene name synonym)|uniprotkb:Proteinase YSCF(gene name synonym) psi-mi:kex2_yeast(display_long)|uniprotkb:KEX2(gene name)|psi-mi:KEX2(display_short)|uniprotkb:QDS1(gene name synonym)|uniprotkb:YNL238W(locus name)|uniprotkb:N1122(orf name)|uniprotkb:Protease KEX2(gene name synonym)|uniprotkb:Proteinase YSCF(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320312|imex:IM-26944-665 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|ensemblfungi:YNL238W(gene)|ensemblfungi:YNL238W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR034182|interpro:IPR036852|rcsb pdb:1OT5|rcsb pdb:1R64|rcsb pdb:2ID4|refseq:NP_014161.1|sgd:S000005182|dip:DIP-6287N|mint:P13134|ensemblgenomes:YNL238W(identity) interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|ensemblfungi:YNL238W(gene)|ensemblfungi:YNL238W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR034182|interpro:IPR036852|rcsb pdb:1OT5|rcsb pdb:1R64|rcsb pdb:2ID4|refseq:NP_014161.1|sgd:S000005182|dip:DIP-6287N|mint:P13134|ensemblgenomes:YNL238W(identity) - crc64:5DCEEDADCF439C78 crc64:5DCEEDADCF439C78 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:DI29wdB9fSIOhlHVEuVoRiDbzl8559292 rogid:DI29wdB9fSIOhlHVEuVoRiDbzl8559292 rigid:bBc/eRASjyAph7jCkwn62XSXjr0 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39704 uniprotkb:P39704 intact:EBI-6587|uniprotkb:D6VPL1|ensemblfungi:YAL007C intact:EBI-6587|uniprotkb:D6VPL1|ensemblfungi:YAL007C psi-mi:erp2_yeast(display_long)|uniprotkb:ERP2(gene name)|psi-mi:ERP2(display_short)|uniprotkb:FUN54(orf name)|uniprotkb:YAL007C(locus name) psi-mi:erp2_yeast(display_long)|uniprotkb:ERP2(gene name)|psi-mi:ERP2(display_short)|uniprotkb:FUN54(orf name)|uniprotkb:YAL007C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320324|imex:IM-26944-221 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009395.1|sgd:S000000005|mint:P39704|dip:DIP-5808N|ensemblfungi:YAL007C(gene)|ensemblfungi:YAL007C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|reactome:R-SCE-6811434|ensemblgenomes:YAL007C(identity) refseq:NP_009395.1|sgd:S000000005|mint:P39704|dip:DIP-5808N|ensemblfungi:YAL007C(gene)|ensemblfungi:YAL007C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|reactome:R-SCE-6811434|ensemblgenomes:YAL007C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:qe1as0AJSSRC8SOKfxboQA2VKtY559292 rogid:qe1as0AJSSRC8SOKfxboQA2VKtY559292 rigid:vuu28mPD7fFkZnfa/VutrHNN1mI false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05359 uniprotkb:Q05359 intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A intact:EBI-6581|uniprotkb:D6VPL7|uniprotkb:E9P8S8|ensemblfungi:YAR002C-A psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:erp1_yeast(display_long)|uniprotkb:ERP1(gene name)|psi-mi:ERP1(display_short)|uniprotkb:YAR002A(orf name)|uniprotkb:YAR002C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320336|imex:IM-26944-223 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434|ensemblgenomes:YAR002C-A(identity) refseq:NP_009402.1|sgd:S000002129|mint:Q05359|dip:DIP-5147N|ensemblfungi:YAR002C-A(gene)|ensemblfungi:YAR002C-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|reactome:R-SCE-6811434|ensemblgenomes:YAR002C-A(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 rogid:RX3ynMqEVNp4bRTVb16YoXaQW3U559292 rigid:BC4mZGXZHM+XfJwU2Kz2uvh8FIA false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35845 uniprotkb:P35845 intact:EBI-12611|uniprotkb:P39555|uniprotkb:P80234|uniprotkb:Q86ZC4|uniprotkb:Q86ZS1|uniprotkb:D6VPN6|ensemblfungi:YAR042W intact:EBI-12611|uniprotkb:P39555|uniprotkb:P80234|uniprotkb:Q86ZC4|uniprotkb:Q86ZS1|uniprotkb:D6VPN6|ensemblfungi:YAR042W psi-mi:osh1_yeast(display_long)|uniprotkb:SWH1(gene name)|psi-mi:SWH1(display_short)|uniprotkb:OSH1(gene name synonym)|uniprotkb:YAR044W(orf name)|uniprotkb:YAR042W(locus name) psi-mi:osh1_yeast(display_long)|uniprotkb:SWH1(gene name)|psi-mi:SWH1(display_short)|uniprotkb:OSH1(gene name synonym)|uniprotkb:YAR044W(orf name)|uniprotkb:YAR042W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320348|imex:IM-26944-667 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YAR042W(gene)|ensemblfungi:YAR042W_mRNA(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0005829"(cytosol)|go:"GO:0008289"(lipid binding)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR036770|interpro:IPR037239|rcsb pdb:5H28|rcsb pdb:5H2C|reactome:R-SCE-192105|refseq:NP_009421.3|sgd:S000000081|mint:P35845|dip:DIP-6839N|ensemblgenomes:YAR042W(identity) ensemblfungi:YAR042W(gene)|ensemblfungi:YAR042W_mRNA(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0005829"(cytosol)|go:"GO:0008289"(lipid binding)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0120015"(sterol transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR036770|interpro:IPR037239|rcsb pdb:5H28|rcsb pdb:5H2C|reactome:R-SCE-192105|refseq:NP_009421.3|sgd:S000000081|mint:P35845|dip:DIP-6839N|ensemblgenomes:YAR042W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:Uag2eKjjL7ua+oy/CfVq+g9FORU559292 rogid:Uag2eKjjL7ua+oy/CfVq+g9FORU559292 rigid:7TS0WwYO+AKd8qV6iycieJNrm5c false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28274 uniprotkb:P28274 intact:EBI-20128|uniprotkb:D6VPW0|ensemblfungi:YBL039C intact:EBI-20128|uniprotkb:D6VPW0|ensemblfungi:YBL039C psi-mi:ura7_yeast(display_long)|uniprotkb:YBL039C(locus name)|uniprotkb:YBL0410(orf name)|uniprotkb:URA7(gene name)|psi-mi:URA7(display_short)|uniprotkb:UTP--ammonia ligase 1(gene name synonym)|uniprotkb:CTP synthetase 1(gene name synonym) psi-mi:ura7_yeast(display_long)|uniprotkb:YBL039C(locus name)|uniprotkb:YBL0410(orf name)|uniprotkb:URA7(gene name)|psi-mi:URA7(display_short)|uniprotkb:UTP--ammonia ligase 1(gene name synonym)|uniprotkb:CTP synthetase 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320360|imex:IM-26944-471 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009514.1|sgd:S000000135|mint:P28274|ensemblfungi:YBL039C(gene)|ensemblfungi:YBL039C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0003883"(CTP synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0019856"(pyrimidine nucleobase biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044210"('de novo' CTP biosynthetic process)|go:"GO:0097268"(cytoophidium)|interpro:IPR004468(CTP synthase)|interpro:IPR017456(CTP synthase, N-terminal)|interpro:IPR017926|interpro:IPR027417|interpro:IPR029062|interpro:IPR033828|reactome:R-SCE-499943|dip:DIP-2954N|ensemblgenomes:YBL039C(identity) refseq:NP_009514.1|sgd:S000000135|mint:P28274|ensemblfungi:YBL039C(gene)|ensemblfungi:YBL039C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0003883"(CTP synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0019856"(pyrimidine nucleobase biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044210"('de novo' CTP biosynthetic process)|go:"GO:0097268"(cytoophidium)|interpro:IPR004468(CTP synthase)|interpro:IPR017456(CTP synthase, N-terminal)|interpro:IPR017926|interpro:IPR027417|interpro:IPR029062|interpro:IPR033828|reactome:R-SCE-499943|dip:DIP-2954N|ensemblgenomes:YBL039C(identity) - crc64:EC3766C83B22ED92 crc64:EC3766C83B22ED92 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:O/aH071giuopuWAjtGPdWti19NQ559292 rogid:O/aH071giuopuWAjtGPdWti19NQ559292 rigid:XYsRGoxzy+/AO0v6M8b+EnVImVQ false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09435 uniprotkb:P09435 intact:EBI-8611|uniprotkb:P18862|uniprotkb:D6VPS7|ensemblfungi:YBL075C intact:EBI-8611|uniprotkb:P18862|uniprotkb:D6VPS7|ensemblfungi:YBL075C psi-mi:hsp73_yeast(display_long)|uniprotkb:YBL06.07(orf name)|uniprotkb:YBL0610(orf name)|uniprotkb:YBL075C(locus name)|uniprotkb:SSA3(gene name)|psi-mi:SSA3(display_short) psi-mi:hsp73_yeast(display_long)|uniprotkb:YBL06.07(orf name)|uniprotkb:YBL0610(orf name)|uniprotkb:YBL075C(locus name)|uniprotkb:SSA3(gene name)|psi-mi:SSA3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320372|imex:IM-26944-473 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009478.1|sgd:S000000171|mint:P09435|dip:DIP-2266N|ensemblfungi:YBL075C(gene)|ensemblfungi:YBL075C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|ensemblgenomes:YBL075C(identity) refseq:NP_009478.1|sgd:S000000171|mint:P09435|dip:DIP-2266N|ensemblfungi:YBL075C(gene)|ensemblfungi:YBL075C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|ensemblgenomes:YBL075C(identity) - crc64:F4B136759B7D4636 crc64:F4B136759B7D4636 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:u3ayjvFHnVNMMrDZdrB7NWaGzBg559292 rogid:u3ayjvFHnVNMMrDZdrB7NWaGzBg559292 rigid:662odJ/6D5Zdpb9qxKBoimmV21Y false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38084 uniprotkb:P38084 intact:EBI-3414|uniprotkb:D6VQ67|ensemblfungi:YBR068C intact:EBI-3414|uniprotkb:D6VQ67|ensemblfungi:YBR068C psi-mi:bap2_yeast(display_long)|uniprotkb:Branched-chain amino-acid permease 2(gene name synonym)|uniprotkb:BAP2(gene name)|psi-mi:BAP2(display_short)|uniprotkb:YBR068C(locus name)|uniprotkb:YBR0629(orf name) psi-mi:bap2_yeast(display_long)|uniprotkb:Branched-chain amino-acid permease 2(gene name synonym)|uniprotkb:BAP2(gene name)|psi-mi:BAP2(display_short)|uniprotkb:YBR068C(locus name)|uniprotkb:YBR0629(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320384|imex:IM-26944-475 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000272|refseq:NP_009624.4|dip:DIP-4910N|mint:P38084|ensemblfungi:YBR068C(gene)|ensemblfungi:YBR068C_mRNA(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015192"(L-phenylalanine transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0098713"(leucine import across plasma membrane)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region)|ensemblgenomes:YBR068C(identity) sgd:S000000272|refseq:NP_009624.4|dip:DIP-4910N|mint:P38084|ensemblfungi:YBR068C(gene)|ensemblfungi:YBR068C_mRNA(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015192"(L-phenylalanine transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0098713"(leucine import across plasma membrane)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region)|ensemblgenomes:YBR068C(identity) - crc64:B87FD6A7464E07F5 crc64:B87FD6A7464E07F5 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:7Fw7+M5mBikZBztHE2tSDpvBi/M559292 rogid:7Fw7+M5mBikZBztHE2tSDpvBi/M559292 rigid:m1ccTPJFhneBln6waVuFdX1OHGE false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33315 uniprotkb:P33315 intact:EBI-19297|uniprotkb:D6VQB5|ensemblfungi:YBR117C intact:EBI-19297|uniprotkb:D6VQB5|ensemblfungi:YBR117C psi-mi:tkt2_yeast(display_long)|uniprotkb:YBR0912(orf name)|uniprotkb:YBR117C(locus name)|uniprotkb:TKL2(gene name)|psi-mi:TKL2(display_short) psi-mi:tkt2_yeast(display_long)|uniprotkb:YBR0912(orf name)|uniprotkb:YBR117C(locus name)|uniprotkb:TKL2(gene name)|psi-mi:TKL2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320396|imex:IM-26944-477 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000321|ensemblfungi:YBR117C(gene)|ensemblfungi:YBR117C_mRNA(transcript)|go:"GO:0004802"(transketolase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0046872"(metal ion binding)|interpro:IPR005474(Transketolase, N-terminal)|interpro:IPR005475(Transketolase, central region)|interpro:IPR005478(Bacterial transketolase)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR020826|interpro:IPR029061|interpro:IPR033247|interpro:IPR033248|refseq:NP_009675.3|dip:DIP-757N|mint:P33315|ensemblgenomes:YBR117C(identity) sgd:S000000321|ensemblfungi:YBR117C(gene)|ensemblfungi:YBR117C_mRNA(transcript)|go:"GO:0004802"(transketolase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0046872"(metal ion binding)|interpro:IPR005474(Transketolase, N-terminal)|interpro:IPR005475(Transketolase, central region)|interpro:IPR005478(Bacterial transketolase)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR020826|interpro:IPR029061|interpro:IPR033247|interpro:IPR033248|refseq:NP_009675.3|dip:DIP-757N|mint:P33315|ensemblgenomes:YBR117C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:Sjs+DFWJRPK+Xd6PoO/CHVNniVE559292 rogid:Sjs+DFWJRPK+Xd6PoO/CHVNniVE559292 rigid:WZLnkVWJdiEy1RhKm2rhKSCAKJM false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P18963 uniprotkb:P18963 intact:EBI-9344|ensemblfungi:YBR140C|uniprotkb:D6VQD6 intact:EBI-9344|ensemblfungi:YBR140C|uniprotkb:D6VQD6 psi-mi:ira1_yeast(display_long)|uniprotkb:IRA1(gene name)|psi-mi:IRA1(display_short)|uniprotkb:GLC1(gene name synonym)|uniprotkb:PPD1(gene name synonym)|uniprotkb:YBR140C(locus name)|uniprotkb:YBR1016(orf name) psi-mi:ira1_yeast(display_long)|uniprotkb:IRA1(gene name)|psi-mi:IRA1(display_short)|uniprotkb:GLC1(gene name synonym)|uniprotkb:PPD1(gene name synonym)|uniprotkb:YBR140C(locus name)|uniprotkb:YBR1016(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320408|imex:IM-26944-555 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YBR140C(gene)|ensemblfungi:YBR140C_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045761"(regulation of adenylate cyclase activity)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR036865|interpro:IPR039360|reactome:R-SCE-9696273|refseq:NP_009698.3|sgd:S000000344|mint:P18963|dip:DIP-2318N|ensemblgenomes:YBR140C(identity) ensemblfungi:YBR140C(gene)|ensemblfungi:YBR140C_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045761"(regulation of adenylate cyclase activity)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR036865|interpro:IPR039360|reactome:R-SCE-9696273|refseq:NP_009698.3|sgd:S000000344|mint:P18963|dip:DIP-2318N|ensemblgenomes:YBR140C(identity) - crc64:291339AE5BD26E08 crc64:291339AE5BD26E08 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:zj7u29Pn0lOWS+ftZ3+2/hFEXhw559292 rogid:zj7u29Pn0lOWS+ftZ3+2/hFEXhw559292 rigid:xHvOtvURK6EPI8S0GHiU6jsERR0 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P05755 uniprotkb:P05755 intact:EBI-16181|ensemblfungi:YBR189W|uniprotkb:D6VQI4 intact:EBI-16181|ensemblfungi:YBR189W|uniprotkb:D6VQI4 psi-mi:rs9b_yeast(display_long)|uniprotkb:RPS9B(gene name)|psi-mi:RPS9B(display_short)|uniprotkb:RPS13B(gene name synonym)|uniprotkb:SUP46(gene name synonym)|uniprotkb:YBR189W(locus name)|uniprotkb:YBR1317(orf name)|uniprotkb:S13(gene name synonym)|uniprotkb:YS11(gene name synonym)|uniprotkb:RP21(gene name synonym)|uniprotkb:YP28(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS4-B(gene name synonym) psi-mi:rs9b_yeast(display_long)|uniprotkb:RPS9B(gene name)|psi-mi:RPS9B(display_short)|uniprotkb:RPS13B(gene name synonym)|uniprotkb:SUP46(gene name synonym)|uniprotkb:YBR189W(locus name)|uniprotkb:YBR1317(orf name)|uniprotkb:S13(gene name synonym)|uniprotkb:YS11(gene name synonym)|uniprotkb:RP21(gene name synonym)|uniprotkb:YP28(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS4-B(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320420|imex:IM-26944-319 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YBR189W(gene)|rcsb pdb:6WOO|ensemblfungi:YBR189W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|reactome:R-SCE-156827|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0019843"(rRNA binding)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0045903"(positive regulation of translational fidelity)|reactome:R-SCE-1799339|reactome:R-SCE-6791226|reactome:R-SCE-72649|reactome:R-SCE-72689|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72706|reactome:R-SCE-975956|reactome:R-SCE-975957|sgd:S000000393|interpro:IPR022801|interpro:IPR005710(Ribosomal protein S4/S9, eukaryotic/archaeal)|interpro:IPR001912(Ribosomal protein S4)|interpro:IPR018079|interpro:IPR002942(RNA-binding S4)|refseq:NP_009748.3|mint:P05755|interpro:IPR036986|ensemblgenomes:YBR189W(identity) ensemblfungi:YBR189W(gene)|rcsb pdb:6WOO|ensemblfungi:YBR189W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|reactome:R-SCE-156827|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0019843"(rRNA binding)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0045903"(positive regulation of translational fidelity)|reactome:R-SCE-1799339|reactome:R-SCE-6791226|reactome:R-SCE-72649|reactome:R-SCE-72689|reactome:R-SCE-72695|reactome:R-SCE-72702|reactome:R-SCE-72706|reactome:R-SCE-975956|reactome:R-SCE-975957|sgd:S000000393|interpro:IPR022801|interpro:IPR005710(Ribosomal protein S4/S9, eukaryotic/archaeal)|interpro:IPR001912(Ribosomal protein S4)|interpro:IPR018079|interpro:IPR002942(RNA-binding S4)|refseq:NP_009748.3|mint:P05755|interpro:IPR036986|ensemblgenomes:YBR189W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:VVaUiekAztpO7wESU7DqtLDIb7E559292 rogid:VVaUiekAztpO7wESU7DqtLDIb7E559292 rigid:ockGLWr0IRjNotrXOlFj5pAjUwc false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32327 uniprotkb:P32327 intact:EBI-14365|uniprotkb:D6VQL4|ensemblfungi:YBR218C intact:EBI-14365|uniprotkb:D6VQL4|ensemblfungi:YBR218C psi-mi:pyc2_yeast(display_long)|uniprotkb:PYC2(gene name)|psi-mi:PYC2(display_short)|uniprotkb:YBR218C(locus name)|uniprotkb:YBR1507(orf name)|uniprotkb:Pyruvic carboxylase 2(gene name synonym) psi-mi:pyc2_yeast(display_long)|uniprotkb:PYC2(gene name)|psi-mi:PYC2(display_short)|uniprotkb:YBR218C(locus name)|uniprotkb:YBR1507(orf name)|uniprotkb:Pyruvic carboxylase 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320432|imex:IM-26944-387 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009777.1|sgd:S000000422|ensemblfungi:YBR218C(gene)|ensemblfungi:YBR218C_mRNA(transcript)|go:"GO:0004736"(pyruvate carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0009374"(biotin binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR001882(Biotin-binding site)|interpro:IPR003379(Conserved carboxylase region)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR005930(Pyruvate carboxylase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|mint:P32327|dip:DIP-6426N|ensemblgenomes:YBR218C(identity) refseq:NP_009777.1|sgd:S000000422|ensemblfungi:YBR218C(gene)|ensemblfungi:YBR218C_mRNA(transcript)|go:"GO:0004736"(pyruvate carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0009374"(biotin binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR001882(Biotin-binding site)|interpro:IPR003379(Conserved carboxylase region)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR005930(Pyruvate carboxylase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|mint:P32327|dip:DIP-6426N|ensemblgenomes:YBR218C(identity) - crc64:AD60DA3A60F5E001 crc64:AD60DA3A60F5E001 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:FvnnWuplwrt91+684m4fpfW2su8559292 rogid:FvnnWuplwrt91+684m4fpfW2su8559292 rigid:SIWVObIrPsAWCMNjIS+q4dw8GG8 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25376 uniprotkb:P25376 intact:EBI-2357|uniprotkb:D6VQZ1|ensemblfungi:YCL025C intact:EBI-2357|uniprotkb:D6VQZ1|ensemblfungi:YCL025C psi-mi:agp1_yeast(display_long)|uniprotkb:AGP1(gene name)|psi-mi:AGP1(display_short)|uniprotkb:YCL025C(locus name)|uniprotkb:YCL25C(orf name)|uniprotkb:Asparagine/glutamine permease(gene name synonym) psi-mi:agp1_yeast(display_long)|uniprotkb:AGP1(gene name)|psi-mi:AGP1(display_short)|uniprotkb:YCL025C(locus name)|uniprotkb:YCL25C(orf name)|uniprotkb:Asparagine/glutamine permease(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320444|imex:IM-26944-141 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009905.3|sgd:S000000530|dip:DIP-4973N|mint:P25376|ensemblfungi:YCL025C(gene)|ensemblfungi:YCL025C_mRNA(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015192"(L-phenylalanine transmembrane transporter activity)|go:"GO:0015193"(L-proline transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0098718"(serine import across plasma membrane)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region)|ensemblgenomes:YCL025C(identity) refseq:NP_009905.3|sgd:S000000530|dip:DIP-4973N|mint:P25376|ensemblfungi:YCL025C(gene)|ensemblfungi:YCL025C_mRNA(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015192"(L-phenylalanine transmembrane transporter activity)|go:"GO:0015193"(L-proline transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0098718"(serine import across plasma membrane)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region)|ensemblgenomes:YCL025C(identity) - crc64:8E19A836C2F6C50F crc64:8E19A836C2F6C50F figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:bB5pBnaoMUTwxlz8v5MAjCWc4Mg559292 rogid:bB5pBnaoMUTwxlz8v5MAjCWc4Mg559292 rigid:zXJbzaNdl/jIxnldAJEZRVDfqVY false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25567 uniprotkb:P25567 intact:EBI-18084|uniprotkb:D6VQX8|ensemblfungi:YCL037C intact:EBI-18084|uniprotkb:D6VQX8|ensemblfungi:YCL037C psi-mi:sro9_yeast(display_long)|uniprotkb:SRO9(gene name)|psi-mi:SRO9(display_short)|uniprotkb:YCL037C(locus name)|uniprotkb:YCL37C(orf name)|uniprotkb:Suppressor of RHO3 protein 9(gene name synonym) psi-mi:sro9_yeast(display_long)|uniprotkb:SRO9(gene name)|psi-mi:SRO9(display_short)|uniprotkb:YCL037C(locus name)|uniprotkb:YCL37C(orf name)|uniprotkb:Suppressor of RHO3 protein 9(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320456|imex:IM-26944-557 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009893.2|sgd:S000000542|ensemblfungi:YCL037C(gene)|ensemblfungi:YCL037C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005844"(polysome)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390|dip:DIP-6638N|mint:P25567|ensemblgenomes:YCL037C(identity) refseq:NP_009893.2|sgd:S000000542|ensemblfungi:YCL037C(gene)|ensemblfungi:YCL037C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005844"(polysome)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390|dip:DIP-6638N|mint:P25567|ensemblgenomes:YCL037C(identity) - crc64:B1B720D40C7B9914 crc64:B1B720D40C7B9914 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:CouwiBsK7S3Tm6CoBsu3LdWfelg559292 rogid:CouwiBsK7S3Tm6CoBsu3LdWfelg559292 rigid:OD4qrMXAbAD+6fsOQ4iR36X1C6o false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P08679 uniprotkb:P08679 intact:EBI-4713|uniprotkb:D6VR15|ensemblfungi:YCR005C intact:EBI-4713|uniprotkb:D6VR15|ensemblfungi:YCR005C psi-mi:cisy2_yeast(display_long)|uniprotkb:CIT2(gene name)|psi-mi:CIT2(display_short)|uniprotkb:YCR043(orf name)|uniprotkb:YCR5C(orf name)|uniprotkb:YCR005C(locus name) psi-mi:cisy2_yeast(display_long)|uniprotkb:CIT2(gene name)|psi-mi:CIT2(display_short)|uniprotkb:YCR043(orf name)|uniprotkb:YCR5C(orf name)|uniprotkb:YCR005C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320468|imex:IM-26944-559 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009931.1|sgd:S000000598|dip:DIP-1259N|mint:P08679|ensemblfungi:YCR005C(gene)|ensemblfungi:YCR005C_mRNA(transcript)|go:"GO:0004108"("citrate (Si)-synthase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005777"(peroxisome)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR002020(Citrate synthase-like)|interpro:IPR010109(Citrate synthase, eukaryotic)|interpro:IPR016142(Citrate synthase-like, large alpha subdomain)|interpro:IPR016143(Citrate synthase-like, small alpha subdomain)|interpro:IPR019810|interpro:IPR036969|ensemblgenomes:YCR005C(identity) refseq:NP_009931.1|sgd:S000000598|dip:DIP-1259N|mint:P08679|ensemblfungi:YCR005C(gene)|ensemblfungi:YCR005C_mRNA(transcript)|go:"GO:0004108"("citrate (Si)-synthase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005777"(peroxisome)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR002020(Citrate synthase-like)|interpro:IPR010109(Citrate synthase, eukaryotic)|interpro:IPR016142(Citrate synthase-like, large alpha subdomain)|interpro:IPR016143(Citrate synthase-like, small alpha subdomain)|interpro:IPR019810|interpro:IPR036969|ensemblgenomes:YCR005C(identity) - crc64:AB2F66AD9A9399EF crc64:AB2F66AD9A9399EF figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:/SK9j3zetaFxY17yqb9qFbRW4K0559292 rogid:/SK9j3zetaFxY17yqb9qFbRW4K0559292 rigid:bNFiU146qXjXpnaNCThQnWOYfbs false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38929 uniprotkb:P38929 intact:EBI-3097|uniprotkb:D6VUD2|ensemblfungi:YGL006W intact:EBI-3097|uniprotkb:D6VUD2|ensemblfungi:YGL006W psi-mi:atc2_yeast(display_long)|uniprotkb:PMC1(gene name)|psi-mi:PMC1(display_short)|uniprotkb:"Vacuolar Ca(2+)-ATPase"(gene name synonym)|uniprotkb:YGL006W(locus name) psi-mi:atc2_yeast(display_long)|uniprotkb:PMC1(gene name)|psi-mi:PMC1(display_short)|uniprotkb:"Vacuolar Ca(2+)-ATPase"(gene name synonym)|uniprotkb:YGL006W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320204|imex:IM-26944-139 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011509.1|sgd:S000002974|dip:DIP-5901N|mint:P38929|ensemblfungi:YGL006W(gene)|ensemblfungi:YGL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-418359|reactome:R-SCE-5578775|reactome:R-SCE-936837|ensemblgenomes:YGL006W(identity) refseq:NP_011509.1|sgd:S000002974|dip:DIP-5901N|mint:P38929|ensemblfungi:YGL006W(gene)|ensemblfungi:YGL006W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0055085"(transmembrane transport)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|reactome:R-SCE-418359|reactome:R-SCE-5578775|reactome:R-SCE-936837|ensemblgenomes:YGL006W(identity) - crc64:5BD9ECFF8508F396 crc64:5BD9ECFF8508F396 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:pvI8E79lFI1hRPK/jgugzIH5LI0559292 rogid:pvI8E79lFI1hRPK/jgugzIH5LI0559292 rigid:Ffzs19kp2f7PQi5RJ7WWUv4XGTA false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19146 uniprotkb:P19146 intact:EBI-2820|uniprotkb:A2TBP3|uniprotkb:D6VRL1|ensemblfungi:YDL137W intact:EBI-2820|uniprotkb:A2TBP3|uniprotkb:D6VRL1|ensemblfungi:YDL137W psi-mi:arf2_yeast(display_long)|uniprotkb:ARF2(gene name)|psi-mi:ARF2(display_short)|uniprotkb:D2165(orf name)|uniprotkb:YDL137W(locus name) psi-mi:arf2_yeast(display_long)|uniprotkb:ARF2(gene name)|psi-mi:ARF2(display_short)|uniprotkb:D2165(orf name)|uniprotkb:YDL137W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320492|imex:IM-26944-479 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010144.1|sgd:S000002296|dip:DIP-2215N|mint:P19146|ensemblfungi:YDL137W(gene)|ensemblfungi:YDL137W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:1MR3|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438|ensemblgenomes:YDL137W(identity) refseq:NP_010144.1|sgd:S000002296|dip:DIP-2215N|mint:P19146|ensemblfungi:YDL137W(gene)|ensemblfungi:YDL137W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:1MR3|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438|ensemblgenomes:YDL137W(identity) - crc64:7E43FF792E8D64E8 crc64:7E43FF792E8D64E8 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:I4V9cXleaZ2sAE2DXGKt8zpAPzw559292 rogid:I4V9cXleaZ2sAE2DXGKt8zpAPzw559292 rigid:trxY2f2Mrf4t/kctnCpnZRis8fQ false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P01098 uniprotkb:P01098 intact:EBI-8080380|intact:MINT-2785764|uniprotkb:D6VRL9|ensemblfungi:YDL130W-A intact:EBI-8080380|intact:MINT-2785764|uniprotkb:D6VRL9|ensemblfungi:YDL130W-A psi-mi:stf1_yeast(display_long)|uniprotkb:STF1(gene name)|psi-mi:STF1(display_short)|uniprotkb:AIS2(gene name synonym)|uniprotkb:ATP synthase F1 subunit epsilon(gene name synonym)|uniprotkb:YDL130BW(orf name)|uniprotkb:YDL130W-A(locus name) psi-mi:stf1_yeast(display_long)|uniprotkb:STF1(gene name)|psi-mi:STF1(display_short)|uniprotkb:AIS2(gene name synonym)|uniprotkb:ATP synthase F1 subunit epsilon(gene name synonym)|uniprotkb:YDL130BW(orf name)|uniprotkb:YDL130W-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320480|imex:IM-26944-561 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010152.1|mint:P01098|interpro:IPR007648(Mitochondrial ATPase inhibitor, IATP)|sgd:S000007232|ensemblfungi:YDL130W-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051117"(ATPase binding)|ensemblfungi:YDL130W-A(gene)|ensemblgenomes:YDL130W-A(identity) refseq:NP_010152.1|mint:P01098|interpro:IPR007648(Mitochondrial ATPase inhibitor, IATP)|sgd:S000007232|ensemblfungi:YDL130W-A_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0051117"(ATPase binding)|ensemblfungi:YDL130W-A(gene)|ensemblgenomes:YDL130W-A(identity) - comment:mint|function:This is 1 of 2 proteins that can stabilize the ATPase-inhibitor complex, which normally dissociates when externally added ATP has been consumed comment:mint|function:This is 1 of 2 proteins that can stabilize the ATPase-inhibitor complex, which normally dissociates when externally added ATP has been consumed figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:YxrqEhb1G8Ln3oLqBYbVRmFM7E4559292 rogid:YxrqEhb1G8Ln3oLqBYbVRmFM7E4559292 rigid:1AlHnUJtKL3I3+Nqn0qW9R9WMqs false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06407 uniprotkb:Q06407 intact:EBI-15060|uniprotkb:D6VT11|ensemblfungi:YDR379W intact:EBI-15060|uniprotkb:D6VT11|ensemblfungi:YDR379W psi-mi:rga2_yeast(display_long)|uniprotkb:RGA2(gene name)|psi-mi:RGA2(display_short)|uniprotkb:D9481.4(orf name)|uniprotkb:YDR379W(locus name) psi-mi:rga2_yeast(display_long)|uniprotkb:RGA2(gene name)|psi-mi:RGA2(display_short)|uniprotkb:D9481.4(orf name)|uniprotkb:YDR379W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320576|imex:IM-26944-229 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010667.1|sgd:S000002787|reactome:R-SCE-8980692|reactome:R-SCE-9013148|reactome:R-SCE-9013405|reactome:R-SCE-9013423|reactome:R-SCE-9035034|ensemblfungi:YDR379W(gene)|ensemblfungi:YDR379W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0031106"(septin ring organization)|go:"GO:0032177"(cellular bud neck split septin rings)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000198(RhoGAP)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-SCE-6798695|dip:DIP-2995N|mint:Q06407|ensemblgenomes:YDR379W(identity) refseq:NP_010667.1|sgd:S000002787|reactome:R-SCE-8980692|reactome:R-SCE-9013148|reactome:R-SCE-9013405|reactome:R-SCE-9013423|reactome:R-SCE-9035034|ensemblfungi:YDR379W(gene)|ensemblfungi:YDR379W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0031106"(septin ring organization)|go:"GO:0032177"(cellular bud neck split septin rings)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000198(RhoGAP)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-SCE-6798695|dip:DIP-2995N|mint:Q06407|ensemblgenomes:YDR379W(identity) - crc64:FA13BA1DF8B35D98 crc64:FA13BA1DF8B35D98 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:0nehE13u+4HaDfljPdHjDjR9znc559292 rogid:0nehE13u+4HaDfljPdHjDjR9znc559292 rigid:OsQ01g31a4Yd2qRWKYCWk9UcGJI false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29509 uniprotkb:P29509 intact:EBI-19497|uniprotkb:D6VSY3|ensemblfungi:YDR353W intact:EBI-19497|uniprotkb:D6VSY3|ensemblfungi:YDR353W psi-mi:trxb1_yeast(display_long)|uniprotkb:D9476.5(orf name)|uniprotkb:YDR353W(locus name)|uniprotkb:TRR1(gene name)|psi-mi:TRR1(display_short) psi-mi:trxb1_yeast(display_long)|uniprotkb:D9476.5(orf name)|uniprotkb:YDR353W(locus name)|uniprotkb:TRR1(gene name)|psi-mi:TRR1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320564|imex:IM-26944-227 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010640.1|sgd:S000002761|ensemblfungi:YDR353W(gene)|ensemblfungi:YDR353W_mRNA(transcript)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0045454"(cell redox homeostasis)|interpro:IPR005982(Thioredoxin reductase)|interpro:IPR008255(Pyridine nucleotide-disulphide oxidoreductase, class-II, active site)|interpro:IPR023753|interpro:IPR036188|rcsb pdb:3D8X|rcsb pdb:3ITJ|dip:DIP-4319N|mint:P29509|ensemblgenomes:YDR353W(identity) refseq:NP_010640.1|sgd:S000002761|ensemblfungi:YDR353W(gene)|ensemblfungi:YDR353W_mRNA(transcript)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0045454"(cell redox homeostasis)|interpro:IPR005982(Thioredoxin reductase)|interpro:IPR008255(Pyridine nucleotide-disulphide oxidoreductase, class-II, active site)|interpro:IPR023753|interpro:IPR036188|rcsb pdb:3D8X|rcsb pdb:3ITJ|dip:DIP-4319N|mint:P29509|ensemblgenomes:YDR353W(identity) - crc64:9F9E58A4BAD859E1 crc64:9F9E58A4BAD859E1 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:mDyO+A1dOgzMtGEDZ5D6nQfqHkw559292 rogid:mDyO+A1dOgzMtGEDZ5D6nQfqHkw559292 rigid:5o2WJTgoAwmiJ5WhXDdlKmPEetU false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P30605 uniprotkb:P30605 intact:EBI-2050956|uniprotkb:D6VTB9|ensemblfungi:YDR497C intact:EBI-2050956|uniprotkb:D6VTB9|ensemblfungi:YDR497C psi-mi:itr1_yeast(display_long)|uniprotkb:D9719.3(orf name)|uniprotkb:YDR497C(locus name)|uniprotkb:ITR1(gene name)|psi-mi:ITR1(display_short) psi-mi:itr1_yeast(display_long)|uniprotkb:D9719.3(orf name)|uniprotkb:YDR497C(locus name)|uniprotkb:ITR1(gene name)|psi-mi:ITR1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320600|imex:IM-26944-389 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010785.1|sgd:S000002905|dip:DIP-7406N|mint:P30605|ensemblfungi:YDR497C(gene)|ensemblfungi:YDR497C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005365"(myo-inositol transmembrane transporter activity)|go:"GO:0005366"("myo-inositol:proton symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0015798"(myo-inositol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|ensemblgenomes:YDR497C(identity) refseq:NP_010785.1|sgd:S000002905|dip:DIP-7406N|mint:P30605|ensemblfungi:YDR497C(gene)|ensemblfungi:YDR497C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005365"(myo-inositol transmembrane transporter activity)|go:"GO:0005366"("myo-inositol:proton symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0015798"(myo-inositol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|ensemblgenomes:YDR497C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:GgtK4YFe7ZCZcmVpV5q1KY2F0Ds559292 rogid:GgtK4YFe7ZCZcmVpV5q1KY2F0Ds559292 rigid:pNNutv5HL4tXqJ7JNj/RPN+pU28 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19358 uniprotkb:P19358 intact:EBI-10795|uniprotkb:E9P927|ensemblfungi:YDR502C|uniprotkb:D6VTC4 intact:EBI-10795|uniprotkb:E9P927|ensemblfungi:YDR502C|uniprotkb:D6VTC4 psi-mi:metk2_yeast(display_long)|uniprotkb:SAM2(gene name)|psi-mi:SAM2(display_short)|uniprotkb:ETH2(gene name synonym)|uniprotkb:YDR502C(locus name)|uniprotkb:D9719.8(orf name)|uniprotkb:Methionine adenosyltransferase 2(gene name synonym) psi-mi:metk2_yeast(display_long)|uniprotkb:SAM2(gene name)|psi-mi:SAM2(display_short)|uniprotkb:ETH2(gene name synonym)|uniprotkb:YDR502C(locus name)|uniprotkb:D9719.8(orf name)|uniprotkb:Methionine adenosyltransferase 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320612|imex:IM-26944-323 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDR502C(gene)|ensemblfungi:YDR502C_mRNA(transcript)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0046872"(metal ion binding)|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022628|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636|reactome:R-SCE-156581|reactome:R-SCE-1614635|reactome:R-SCE-2408508|go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006555"(methionine metabolic process)|sgd:S000002910|refseq:NP_010790.3|mint:P19358|dip:DIP-4001N|ensemblgenomes:YDR502C(identity) ensemblfungi:YDR502C(gene)|ensemblfungi:YDR502C_mRNA(transcript)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0046872"(metal ion binding)|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022628|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636|reactome:R-SCE-156581|reactome:R-SCE-1614635|reactome:R-SCE-2408508|go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006555"(methionine metabolic process)|sgd:S000002910|refseq:NP_010790.3|mint:P19358|dip:DIP-4001N|ensemblgenomes:YDR502C(identity) - crc64:0AFCB0BA386F088B crc64:0AFCB0BA386F088B figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:fLg9TMOk+nR4ZuRNqkqur0qzv/E559292 rogid:fLg9TMOk+nR4ZuRNqkqur0qzv/E559292 rigid:H2vqyIJEBImVPfMMXVNUpMK9AZg false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40036 uniprotkb:P40036 intact:EBI-7612|uniprotkb:D3DLV7|ensemblfungi:YER054C intact:EBI-7612|uniprotkb:D3DLV7|ensemblfungi:YER054C psi-mi:gip2_yeast(display_long)|uniprotkb:YER054C(locus name)|uniprotkb:GIP2(gene name)|psi-mi:GIP2(display_short) psi-mi:gip2_yeast(display_long)|uniprotkb:YER054C(locus name)|uniprotkb:GIP2(gene name)|psi-mi:GIP2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320624|imex:IM-26944-669 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010974.1|sgd:S000000856|mint:P40036|dip:DIP-2376N|ensemblfungi:YER054C(gene)|ensemblfungi:YER054C_mRNA(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:2001069"(glycogen binding)|interpro:IPR005036(Putative phosphatase regulatory subunit)|interpro:IPR016717(Protein phosphatase type 1-interacting protein)|interpro:IPR038175|reactome:R-SCE-3322077|ensemblgenomes:YER054C(identity) refseq:NP_010974.1|sgd:S000000856|mint:P40036|dip:DIP-2376N|ensemblfungi:YER054C(gene)|ensemblfungi:YER054C_mRNA(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:2001069"(glycogen binding)|interpro:IPR005036(Putative phosphatase regulatory subunit)|interpro:IPR016717(Protein phosphatase type 1-interacting protein)|interpro:IPR038175|reactome:R-SCE-3322077|ensemblgenomes:YER054C(identity) - crc64:B28EE5241989A9BF crc64:B28EE5241989A9BF figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:DU6TcuoGmo6v+YNFOGMozundYoE559292 rogid:DU6TcuoGmo6v+YNFOGMozundYoE559292 rigid:j6FaqYSIaBPWZjd+8Vf56TMVLzs false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40037 uniprotkb:P40037 intact:EBI-8389|uniprotkb:D3DLW1|ensemblfungi:YER057C intact:EBI-8389|uniprotkb:D3DLW1|ensemblfungi:YER057C psi-mi:hmf1_yeast(display_long)|uniprotkb:HMF1(gene name)|psi-mi:HMF1(display_short)|uniprotkb:HIG1(gene name synonym)|uniprotkb:High dosage growth inhibitor(gene name synonym)|uniprotkb:Homologous mitochondrial matrix factor 1(gene name synonym)|uniprotkb:YER057C(locus name) psi-mi:hmf1_yeast(display_long)|uniprotkb:HMF1(gene name)|psi-mi:HMF1(display_short)|uniprotkb:HIG1(gene name synonym)|uniprotkb:High dosage growth inhibitor(gene name synonym)|uniprotkb:Homologous mitochondrial matrix factor 1(gene name synonym)|uniprotkb:YER057C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320636|imex:IM-26944-147 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000859|refseq:NP_010978.3|dip:DIP-4314N|mint:P40037|ensemblfungi:YER057C(gene)|ensemblfungi:YER057C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0019239"(deaminase activity)|go:"GO:1901565"(organonitrogen compound catabolic process)|interpro:IPR006056(YjgF-like protein)|interpro:IPR006175(Endoribonuclease L-PSP)|interpro:IPR019897|interpro:IPR035959|rcsb pdb:1JD1|ensemblgenomes:YER057C(identity) sgd:S000000859|refseq:NP_010978.3|dip:DIP-4314N|mint:P40037|ensemblfungi:YER057C(gene)|ensemblfungi:YER057C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0019239"(deaminase activity)|go:"GO:1901565"(organonitrogen compound catabolic process)|interpro:IPR006056(YjgF-like protein)|interpro:IPR006175(Endoribonuclease L-PSP)|interpro:IPR019897|interpro:IPR035959|rcsb pdb:1JD1|ensemblgenomes:YER057C(identity) - crc64:D1D252BBA47F81E8 crc64:D1D252BBA47F81E8 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:XCScAuZc5h+pEgQlI2obiHQ+0w4559292 rogid:XCScAuZc5h+pEgQlI2obiHQ+0w4559292 rigid:8X2sItH+AMNi7NovgTiESh+Cd1c false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40043 uniprotkb:P40043 intact:EBI-22569|uniprotkb:D3DLX2|ensemblfungi:YER067W intact:EBI-22569|uniprotkb:D3DLX2|ensemblfungi:YER067W psi-mi:rgi1_yeast(display_long)|uniprotkb:YER067W(locus name)|uniprotkb:RGI1(gene name)|psi-mi:RGI1(display_short) psi-mi:rgi1_yeast(display_long)|uniprotkb:YER067W(locus name)|uniprotkb:RGI1(gene name)|psi-mi:RGI1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320648|imex:IM-26944-565 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010990.1|sgd:S000000869|dip:DIP-5346N|mint:P40043|ensemblfungi:YER067W(gene)|ensemblfungi:YER067W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0071944"(cell periphery)|interpro:IPR022554|interpro:IPR038235|rcsb pdb:3BCY|ensemblgenomes:YER067W(identity) refseq:NP_010990.1|sgd:S000000869|dip:DIP-5346N|mint:P40043|ensemblfungi:YER067W(gene)|ensemblfungi:YER067W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0071944"(cell periphery)|interpro:IPR022554|interpro:IPR038235|rcsb pdb:3BCY|ensemblgenomes:YER067W(identity) - crc64:31C2929EBB19BF37 crc64:31C2929EBB19BF37 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:yG26lstoIyZ/u3X4ZFkjvDvH7as559292 rogid:yG26lstoIyZ/u3X4ZFkjvDvH7as559292 rigid:ycmCa9BIg6iEtruwwjCpzvbMWzM false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40054 uniprotkb:P40054 intact:EBI-16961|uniprotkb:D3DLY8|ensemblfungi:YER081W intact:EBI-16961|uniprotkb:D3DLY8|ensemblfungi:YER081W psi-mi:sera_yeast(display_long)|uniprotkb:SER3(gene name)|psi-mi:SER3(display_short)|uniprotkb:2-oxoglutarate reductase(gene name synonym)|uniprotkb:YER081W(locus name) psi-mi:sera_yeast(display_long)|uniprotkb:SER3(gene name)|psi-mi:SER3(display_short)|uniprotkb:2-oxoglutarate reductase(gene name synonym)|uniprotkb:YER081W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320660|imex:IM-26944-483 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011004.3|sgd:S000000883|ensemblfungi:YER081W(gene)|ensemblfungi:YER081W_mRNA(transcript)|go:"GO:0004617"(phosphoglycerate dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0009070"(serine family amino acid biosynthetic process)|go:"GO:0016618"(hydroxypyruvate reductase activity)|go:"GO:0030267"("glyoxylate reductase (NADP+) activity")|go:"GO:0051287"(NAD binding)|go:"GO:0061759"(alpha-ketoglutarate reductase activity)|interpro:IPR002912(Amino acid-binding ACT)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|dip:DIP-5336N|mint:P40054|ensemblgenomes:YER081W(identity) refseq:NP_011004.3|sgd:S000000883|ensemblfungi:YER081W(gene)|ensemblfungi:YER081W_mRNA(transcript)|go:"GO:0004617"(phosphoglycerate dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0009070"(serine family amino acid biosynthetic process)|go:"GO:0016618"(hydroxypyruvate reductase activity)|go:"GO:0030267"("glyoxylate reductase (NADP+) activity")|go:"GO:0051287"(NAD binding)|go:"GO:0061759"(alpha-ketoglutarate reductase activity)|interpro:IPR002912(Amino acid-binding ACT)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|dip:DIP-5336N|mint:P40054|ensemblgenomes:YER081W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:liGD7+FpTgCZYiHWbejPHNYk6As559292 rogid:liGD7+FpTgCZYiHWbejPHNYk6As559292 rigid:AKRhPRcmn+S8XBNkHisbavbngVQ false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43555 uniprotkb:P43555 intact:EBI-6439|uniprotkb:D6VTI2|ensemblfungi:YFL048C intact:EBI-6439|uniprotkb:D6VTI2|ensemblfungi:YFL048C psi-mi:emp47_yeast(display_long)|uniprotkb:YFL048C(locus name)|uniprotkb:EMP47(gene name)|psi-mi:EMP47(display_short)|uniprotkb:47 kDa endomembrane protein(gene name synonym)|uniprotkb:Endosomal P44 protein(gene name synonym) psi-mi:emp47_yeast(display_long)|uniprotkb:YFL048C(locus name)|uniprotkb:EMP47(gene name)|psi-mi:EMP47(display_short)|uniprotkb:47 kDa endomembrane protein(gene name synonym)|uniprotkb:Endosomal P44 protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320672|imex:IM-26944-325 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116606.1|sgd:S000001846|mint:P43555|dip:DIP-7675N|ensemblfungi:YFL048C(gene)|ensemblfungi:YFL048C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0097367"(carbohydrate derivative binding)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR016710(L-type lectin, fungi)|interpro:IPR035661|rcsb pdb:2A6Y|rcsb pdb:2A6Z|rcsb pdb:2A70|rcsb pdb:2A71|ensemblgenomes:YFL048C(identity) refseq:NP_116606.1|sgd:S000001846|mint:P43555|dip:DIP-7675N|ensemblfungi:YFL048C(gene)|ensemblfungi:YFL048C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0097367"(carbohydrate derivative binding)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR016710(L-type lectin, fungi)|interpro:IPR035661|rcsb pdb:2A6Y|rcsb pdb:2A6Z|rcsb pdb:2A70|rcsb pdb:2A71|ensemblgenomes:YFL048C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:gq6bd7YuqqXJ+mHOhe1OZ0WU3K4559292 rogid:gq6bd7YuqqXJ+mHOhe1OZ0WU3K4559292 rigid:n+Ty6Un+FUlQ3EEhlEzPH+58M3E false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23337 uniprotkb:P23337 intact:EBI-8031|uniprotkb:D6VTP6|ensemblfungi:YFR015C intact:EBI-8031|uniprotkb:D6VTP6|ensemblfungi:YFR015C psi-mi:gys1_yeast(display_long)|uniprotkb:YFR015C(locus name)|uniprotkb:GSY1(gene name)|psi-mi:GSY1(display_short) psi-mi:gys1_yeast(display_long)|uniprotkb:YFR015C(locus name)|uniprotkb:GSY1(gene name)|psi-mi:GSY1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320684|imex:IM-26944-231 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116670.1|sgd:S000001911|mint:P23337|dip:DIP-5354N|ensemblfungi:YFR015C(gene)|ensemblfungi:YFR015C_mRNA(transcript)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005978"(glycogen biosynthetic process)|interpro:IPR008631(Glycogen synthase)|reactome:R-SCE-3322077|ensemblgenomes:YFR015C(identity) refseq:NP_116670.1|sgd:S000001911|mint:P23337|dip:DIP-5354N|ensemblfungi:YFR015C(gene)|ensemblfungi:YFR015C_mRNA(transcript)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005978"(glycogen biosynthetic process)|interpro:IPR008631(Glycogen synthase)|reactome:R-SCE-3322077|ensemblgenomes:YFR015C(identity) - crc64:9EF2D3858529E68A crc64:9EF2D3858529E68A figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:YDyqS1ELi4nkwAfLsPv+FNzh87k559292 rogid:YDyqS1ELi4nkwAfLsPv+FNzh87k559292 rigid:M6/6bKGtnj8aGzWG8ch9cBTFqAE false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43603 uniprotkb:P43603 intact:EBI-22980|uniprotkb:D6VTQ4|ensemblfungi:YFR024C-A intact:EBI-22980|uniprotkb:D6VTQ4|ensemblfungi:YFR024C-A psi-mi:lsb3_yeast(display_long)|uniprotkb:LSB3(gene name)|psi-mi:LSB3(display_short)|uniprotkb:YFR024C(orf name)|uniprotkb:YFR024C-A(locus name) psi-mi:lsb3_yeast(display_long)|uniprotkb:LSB3(gene name)|psi-mi:LSB3(display_short)|uniprotkb:YFR024C(orf name)|uniprotkb:YFR024C-A(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320696|imex:IM-26944-39 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002968|refseq:NP_219497.4|dip:DIP-6259N|mint:P43603|ensemblfungi:YFR024C-A(gene)|ensemblfungi:YFR024C-A_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005935"(cellular bud neck)|go:"GO:0030479"(actin cortical patch)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization)|interpro:IPR001452(Src homology-3)|interpro:IPR007461(Protein of unknown function DUF500)|interpro:IPR033643|interpro:IPR036028|rcsb pdb:1OOT|rcsb pdb:1SSH|ensemblgenomes:YFR024C-A(identity) sgd:S000002968|refseq:NP_219497.4|dip:DIP-6259N|mint:P43603|ensemblfungi:YFR024C-A(gene)|ensemblfungi:YFR024C-A_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005935"(cellular bud neck)|go:"GO:0030479"(actin cortical patch)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization)|interpro:IPR001452(Src homology-3)|interpro:IPR007461(Protein of unknown function DUF500)|interpro:IPR033643|interpro:IPR036028|rcsb pdb:1OOT|rcsb pdb:1SSH|ensemblgenomes:YFR024C-A(identity) - crc64:F486C787B5771AAC crc64:F486C787B5771AAC figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:zKMZQRpG4d/at/NecQDyEi/kVKg559292 rogid:zKMZQRpG4d/at/NecQDyEi/kVKg559292 rigid:mJIl1BGotMFDGU4tKTOkGMwOODk false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12443 uniprotkb:Q12443 intact:EBI-32591|uniprotkb:D6VRF0|ensemblfungi:YDL204W intact:EBI-32591|uniprotkb:D6VRF0|ensemblfungi:YDL204W psi-mi:rtn2_yeast(display_long)|uniprotkb:RTN2(gene name)|psi-mi:RTN2(display_short)|uniprotkb:D1062(orf name)|uniprotkb:YDL204W(locus name) psi-mi:rtn2_yeast(display_long)|uniprotkb:RTN2(gene name)|psi-mi:RTN2(display_short)|uniprotkb:D1062(orf name)|uniprotkb:YDL204W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320504|imex:IM-26944-143 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010077.1|sgd:S000002363|dip:DIP-4231N|mint:Q12443|ensemblfungi:YDL204W(gene)|ensemblfungi:YDL204W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032581"(ER-dependent peroxisome organization)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0071788"(endoplasmic reticulum tubular network maintenance)|go:"GO:0071944"(cell periphery)|interpro:IPR003388(Reticulon)|ensemblgenomes:YDL204W(identity) refseq:NP_010077.1|sgd:S000002363|dip:DIP-4231N|mint:Q12443|ensemblfungi:YDL204W(gene)|ensemblfungi:YDL204W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032581"(ER-dependent peroxisome organization)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0071788"(endoplasmic reticulum tubular network maintenance)|go:"GO:0071944"(cell periphery)|interpro:IPR003388(Reticulon)|ensemblgenomes:YDL204W(identity) - crc64:E937E2B77759DFF5 crc64:E937E2B77759DFF5 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:jF49AeaM5t7a5TBw3/+tJ7H251g559292 rogid:jF49AeaM5t7a5TBw3/+tJ7H251g559292 rigid:9q2+qwWOjsxi/BffVhZYCYlcQAA false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01589 uniprotkb:Q01589 intact:EBI-16917|uniprotkb:D6VS63|uniprotkb:Q6Q5U8|uniprotkb:Q8J057|uniprotkb:Q8J270|uniprotkb:Q8J271|uniprotkb:Q8J272|uniprotkb:Q8J273|uniprotkb:Q8J274|uniprotkb:Q8J275|ensemblfungi:YDR077W intact:EBI-16917|uniprotkb:D6VS63|uniprotkb:Q6Q5U8|uniprotkb:Q8J057|uniprotkb:Q8J270|uniprotkb:Q8J271|uniprotkb:Q8J272|uniprotkb:Q8J273|uniprotkb:Q8J274|uniprotkb:Q8J275|ensemblfungi:YDR077W psi-mi:sed1_yeast(display_long)|uniprotkb:SED1(gene name)|psi-mi:SED1(display_short)|uniprotkb:YDR077W(locus name)|uniprotkb:D4431(orf name)|uniprotkb:Glycoprotein GP260(gene name synonym) psi-mi:sed1_yeast(display_long)|uniprotkb:SED1(gene name)|psi-mi:SED1(display_short)|uniprotkb:YDR077W(locus name)|uniprotkb:D4431(orf name)|uniprotkb:Glycoprotein GP260(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320516|imex:IM-26944-563 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010362.3|sgd:S000002484|ensemblfungi:YDR077W(gene)|ensemblfungi:YDR077W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005199"(structural constituent of cell wall)|go:"GO:0005576"(extracellular region)|go:"GO:0005739"(mitochondrion)|go:"GO:0005840"(ribosome)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0071944"(cell periphery)|interpro:IPR038843|dip:DIP-1613N|ensemblgenomes:YDR077W(identity) refseq:NP_010362.3|sgd:S000002484|ensemblfungi:YDR077W(gene)|ensemblfungi:YDR077W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005199"(structural constituent of cell wall)|go:"GO:0005576"(extracellular region)|go:"GO:0005739"(mitochondrion)|go:"GO:0005840"(ribosome)|go:"GO:0009277"(fungal-type cell wall)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0071944"(cell periphery)|interpro:IPR038843|dip:DIP-1613N|ensemblgenomes:YDR077W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:4Oyb3fialIFuwCLzsRFRcTML3ng559292 rogid:4Oyb3fialIFuwCLzsRFRcTML3ng559292 rigid:kp9xfzGJgsbKEhBI+MkOltizoqs false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34730 uniprotkb:P34730 intact:EBI-3672|uniprotkb:A2TBP2|uniprotkb:Q06HN5|uniprotkb:D6VS86|ensemblfungi:YDR099W intact:EBI-3672|uniprotkb:A2TBP2|uniprotkb:Q06HN5|uniprotkb:D6VS86|ensemblfungi:YDR099W psi-mi:bmh2_yeast(display_long)|uniprotkb:YD8557.08(orf name)|uniprotkb:YDR099W(locus name)|uniprotkb:BMH2(gene name)|psi-mi:BMH2(display_short) psi-mi:bmh2_yeast(display_long)|uniprotkb:YD8557.08(orf name)|uniprotkb:YDR099W(locus name)|uniprotkb:BMH2(gene name)|psi-mi:BMH2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320540|imex:IM-26944-481 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002506|refseq:NP_010384.3|dip:DIP-1212N|mint:P34730|ensemblfungi:YDR099W(gene)|ensemblfungi:YDR099W_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0030437"(ascospore formation)|go:"GO:0034221"(fungal-type cell wall chitin biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0070873"(regulation of glycogen metabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|ensemblgenomes:YDR099W(identity) sgd:S000002506|refseq:NP_010384.3|dip:DIP-1212N|mint:P34730|ensemblfungi:YDR099W(gene)|ensemblfungi:YDR099W_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0030437"(ascospore formation)|go:"GO:0034221"(fungal-type cell wall chitin biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0070873"(regulation of glycogen metabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|ensemblgenomes:YDR099W(identity) - crc64:74788A9103F129FB crc64:74788A9103F129FB figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:trVbn5NvV8o+49WbsQrvedJbAZI559292 rogid:trVbn5NvV8o+49WbsQrvedJbAZI559292 rigid:xjNgo+p6NKUGP/QM1LtsSriirhs false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12675 uniprotkb:Q12675 intact:EBI-3114|uniprotkb:D6VS80|ensemblfungi:YDR093W intact:EBI-3114|uniprotkb:D6VS80|ensemblfungi:YDR093W psi-mi:atc4_yeast(display_long)|uniprotkb:DNF2(gene name)|psi-mi:DNF2(display_short)|uniprotkb:YDR093W(locus name)|uniprotkb:YD8557.01(orf name)|uniprotkb:Flippase DNF2(gene name synonym) psi-mi:atc4_yeast(display_long)|uniprotkb:DNF2(gene name)|psi-mi:DNF2(display_short)|uniprotkb:YDR093W(locus name)|uniprotkb:YD8557.01(orf name)|uniprotkb:Flippase DNF2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320528|imex:IM-26944-321 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010378.1|sgd:S000002500|dip:DIP-8055N|mint:Q12675|ensemblfungi:YDR093W(gene)|ensemblfungi:YDR093W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0015031"(protein transport)|go:"GO:0015247"(aminophospholipid flippase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140346"(phosphatidylserine flippase activity)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR026871|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:7KY5|rcsb pdb:7KY7|rcsb pdb:7KY8|rcsb pdb:7KY9|rcsb pdb:7KYA|ensemblgenomes:YDR093W(identity) refseq:NP_010378.1|sgd:S000002500|dip:DIP-8055N|mint:Q12675|ensemblfungi:YDR093W(gene)|ensemblfungi:YDR093W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0015031"(protein transport)|go:"GO:0015247"(aminophospholipid flippase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140346"(phosphatidylserine flippase activity)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR026871|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:7KY5|rcsb pdb:7KY7|rcsb pdb:7KY8|rcsb pdb:7KY9|rcsb pdb:7KYA|ensemblgenomes:YDR093W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:yfYH/L8WpAsxluGHGiYw3loRtRM559292 rogid:yfYH/L8WpAsxluGHGiYw3loRtRM559292 rigid:Zk2LvQHZ0xiM8U7L2+Iz/orUAtc false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32466 uniprotkb:P32466 intact:EBI-8770|ensemblfungi:YDR345C|uniprotkb:D6VSX5 intact:EBI-8770|ensemblfungi:YDR345C|uniprotkb:D6VSX5 psi-mi:hxt3_yeast(display_long)|uniprotkb:D9651.14(orf name)|uniprotkb:YDR345C(locus name)|uniprotkb:HXT3(gene name)|psi-mi:HXT3(display_short) psi-mi:hxt3_yeast(display_long)|uniprotkb:D9651.14(orf name)|uniprotkb:YDR345C(locus name)|uniprotkb:HXT3(gene name)|psi-mi:HXT3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320552|imex:IM-26944-225 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|interpro:IPR005828(General substrate transporter)|ensemblfungi:YDR345C(gene)|ensemblfungi:YDR345C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|refseq:NP_010632.1|sgd:S000002753|mint:P32466|dip:DIP-4178N|ensemblgenomes:YDR345C(identity) interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|interpro:IPR005828(General substrate transporter)|ensemblfungi:YDR345C(gene)|ensemblfungi:YDR345C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|refseq:NP_010632.1|sgd:S000002753|mint:P32466|dip:DIP-4178N|ensemblgenomes:YDR345C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:sklAjpmtbPADWjK3sLElxkiGw6k559292 rogid:sklAjpmtbPADWjK3sLElxkiGw6k559292 rigid:grdrqjNiJH3sLihVFTeww9aFJaQ false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32324 uniprotkb:P32324 intact:EBI-6333|uniprotkb:Q6JEF7|uniprotkb:D6VT19|ensemblfungi:YDR385W|ensemblfungi:YOR133W intact:EBI-6333|uniprotkb:Q6JEF7|uniprotkb:D6VT19|ensemblfungi:YDR385W|ensemblfungi:YOR133W psi-mi:ef2_yeast(display_long)|uniprotkb:EFT1(gene name)|psi-mi:EFT1(display_short)|uniprotkb:YOR133W(locus name)|uniprotkb:O3317(orf name)|uniprotkb:YOR3317W(orf name)|uniprotkb:EFT2(gene name)|psi-mi:EFT2(display_short)|uniprotkb:YDR385W(locus name)|uniprotkb:Translation elongation factor 2(gene name synonym)|uniprotkb:Eukaryotic elongation factor 2(gene name synonym)|uniprotkb:Ribosomal translocase(gene name synonym) psi-mi:ef2_yeast(display_long)|uniprotkb:EFT1(gene name)|psi-mi:EFT1(display_short)|uniprotkb:YOR133W(locus name)|uniprotkb:O3317(orf name)|uniprotkb:YOR3317W(orf name)|uniprotkb:EFT2(gene name)|psi-mi:EFT2(display_short)|uniprotkb:YDR385W(locus name)|uniprotkb:Translation elongation factor 2(gene name synonym)|uniprotkb:Eukaryotic elongation factor 2(gene name synonym)|uniprotkb:Ribosomal translocase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320588|imex:IM-26944-145 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010673.1|refseq:NP_014776.1|sgd:S000005659|sgd:S000002793|ensemblfungi:YDR385W(gene)|ensemblfungi:YDR385W_mRNA(transcript)|ensemblfungi:YOR133W(gene)|ensemblfungi:YOR133W_mRNA(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0019843"(rRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0051087"(chaperone binding)|go:"GO:1990145"(maintenance of translational fidelity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|mint:P32324|dip:DIP-4911N|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|rcsb pdb:1N0U|rcsb pdb:1N0V|rcsb pdb:1U2R|rcsb pdb:1ZM2|rcsb pdb:1ZM3|rcsb pdb:1ZM4|rcsb pdb:1ZM9|rcsb pdb:2E1R|rcsb pdb:2NPF|rcsb pdb:2P8W|rcsb pdb:2P8X|rcsb pdb:2P8Y|rcsb pdb:2P8Z|rcsb pdb:2ZIT|rcsb pdb:3B78|rcsb pdb:3B82|rcsb pdb:3B8H|rcsb pdb:3DNY|rcsb pdb:4V4B|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|reactome:R-SCE-156902|reactome:R-SCE-5358493|reactome:R-SCE-6798695|ensemblgenomes:YDR385W(identity) refseq:NP_010673.1|refseq:NP_014776.1|sgd:S000005659|sgd:S000002793|ensemblfungi:YDR385W(gene)|ensemblfungi:YDR385W_mRNA(transcript)|ensemblfungi:YOR133W(gene)|ensemblfungi:YOR133W_mRNA(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0019843"(rRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0051087"(chaperone binding)|go:"GO:1990145"(maintenance of translational fidelity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|mint:P32324|dip:DIP-4911N|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|rcsb pdb:1N0U|rcsb pdb:1N0V|rcsb pdb:1U2R|rcsb pdb:1ZM2|rcsb pdb:1ZM3|rcsb pdb:1ZM4|rcsb pdb:1ZM9|rcsb pdb:2E1R|rcsb pdb:2NPF|rcsb pdb:2P8W|rcsb pdb:2P8X|rcsb pdb:2P8Y|rcsb pdb:2P8Z|rcsb pdb:2ZIT|rcsb pdb:3B78|rcsb pdb:3B82|rcsb pdb:3B8H|rcsb pdb:3DNY|rcsb pdb:4V4B|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|reactome:R-SCE-156902|reactome:R-SCE-5358493|reactome:R-SCE-6798695|ensemblgenomes:YDR385W(identity) - crc64:FD2F8073CB9B66AA crc64:FD2F8073CB9B66AA figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:mlyt9YKZrGhGbsSlvxNJ0p1C67I559292 rogid:mlyt9YKZrGhGbsSlvxNJ0p1C67I559292 rigid:jWPbFhrzSUX8llcuPU1CyVbbIq4 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07804 uniprotkb:Q07804 intact:EBI-36254|uniprotkb:D6VXZ0|ensemblfungi:YLL012W intact:EBI-36254|uniprotkb:D6VXZ0|ensemblfungi:YLL012W psi-mi:yeh1_yeast(display_long)|uniprotkb:Steryl ester hydrolase 1(gene name synonym)|uniprotkb:YEH1(gene name)|psi-mi:YEH1(display_short)|uniprotkb:YLL012W(locus name)|uniprotkb:L1329(orf name) psi-mi:yeh1_yeast(display_long)|uniprotkb:Steryl ester hydrolase 1(gene name synonym)|uniprotkb:YEH1(gene name)|psi-mi:YEH1(display_short)|uniprotkb:YLL012W(locus name)|uniprotkb:L1329(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320936|imex:IM-26944-331 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013089.1|sgd:S000003935|mint:Q07804|dip:DIP-4156N|ensemblfungi:YLL012W(gene)|ensemblfungi:YLL012W_mRNA(transcript)|go:"GO:0004771"(sterol esterase activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016125"(sterol metabolic process)|interpro:IPR006693(AB-hydrolase associated lipase region)|interpro:IPR029058|reactome:R-SCE-192456|reactome:R-SCE-6809371|ensemblgenomes:YLL012W(identity) refseq:NP_013089.1|sgd:S000003935|mint:Q07804|dip:DIP-4156N|ensemblfungi:YLL012W(gene)|ensemblfungi:YLL012W_mRNA(transcript)|go:"GO:0004771"(sterol esterase activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016125"(sterol metabolic process)|interpro:IPR006693(AB-hydrolase associated lipase region)|interpro:IPR029058|reactome:R-SCE-192456|reactome:R-SCE-6809371|ensemblgenomes:YLL012W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:Fv+RBBi6c7i++sW0AISZDXDrlrI559292 rogid:Fv+RBBi6c7i++sW0AISZDXDrlrI559292 rigid:We4cfjVEHiqQRcomDN4RiLZbBDA false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36165 uniprotkb:P36165 intact:EBI-26531|uniprotkb:D6VXE9|ensemblfungi:YKR089C intact:EBI-26531|uniprotkb:D6VXE9|ensemblfungi:YKR089C psi-mi:tgl4_yeast(display_long)|uniprotkb:YKR089C(locus name)|uniprotkb:YKR409(orf name)|uniprotkb:TGL4(gene name)|psi-mi:TGL4(display_short)|uniprotkb:STC1(gene name synonym)|uniprotkb:Lipase 4(gene name synonym) psi-mi:tgl4_yeast(display_long)|uniprotkb:YKR089C(locus name)|uniprotkb:YKR409(orf name)|uniprotkb:TGL4(gene name)|psi-mi:TGL4(display_short)|uniprotkb:STC1(gene name synonym)|uniprotkb:Lipase 4(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320924|imex:IM-26944-151 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013015.1|sgd:S000001797|mint:P36165|dip:DIP-5588N|ensemblfungi:YKR089C(gene)|ensemblfungi:YKR089C_mRNA(transcript)|go:"GO:0004771"(sterol esterase activity)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0007114"(cell budding)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042171"(lysophosphatidic acid acyltransferase activity)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|interpro:IPR002641(Patatin)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR021771|ensemblgenomes:YKR089C(identity) refseq:NP_013015.1|sgd:S000001797|mint:P36165|dip:DIP-5588N|ensemblfungi:YKR089C(gene)|ensemblfungi:YKR089C_mRNA(transcript)|go:"GO:0004771"(sterol esterase activity)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0007114"(cell budding)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042171"(lysophosphatidic acid acyltransferase activity)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|interpro:IPR002641(Patatin)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR021771|ensemblgenomes:YKR089C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:VEfeOj6QZCY2MIMeme5kaVZBQx8559292 rogid:VEfeOj6QZCY2MIMeme5kaVZBQx8559292 rigid:hD+ORKZALU0au7LZnowP+jfhquk false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36024 uniprotkb:P36024 intact:EBI-17250|uniprotkb:D6VXD3|ensemblfungi:YKR072C intact:EBI-17250|uniprotkb:D6VXD3|ensemblfungi:YKR072C psi-mi:sis2_yeast(display_long)|uniprotkb:SIS2(gene name)|psi-mi:SIS2(display_short)|uniprotkb:HAL3(gene name synonym)|uniprotkb:YKR072C(locus name)|uniprotkb:Halotolerance protein HAL3(gene name synonym)|uniprotkb:Sit4 suppressor 2(gene name synonym) psi-mi:sis2_yeast(display_long)|uniprotkb:SIS2(gene name)|psi-mi:SIS2(display_short)|uniprotkb:HAL3(gene name synonym)|uniprotkb:YKR072C(locus name)|uniprotkb:Halotolerance protein HAL3(gene name synonym)|uniprotkb:Sit4 suppressor 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320912|imex:IM-26944-43 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012998.1|sgd:S000001780|ensemblfungi:YKR072C(gene)|ensemblfungi:YKR072C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003824"(catalytic activity)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0009651"(response to salt stress)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|dip:DIP-2521N|mint:P36024|ensemblgenomes:YKR072C(identity) refseq:NP_012998.1|sgd:S000001780|ensemblfungi:YKR072C(gene)|ensemblfungi:YKR072C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003824"(catalytic activity)|go:"GO:0004865"(protein serine/threonine phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0009651"(response to salt stress)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|dip:DIP-2521N|mint:P36024|ensemblgenomes:YKR072C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:oiDiGYmZy7PE7zchnyTa2x4g9zo559292 rogid:oiDiGYmZy7PE7zchnyTa2x4g9zo559292 rigid:0CU9nz1yBj2N3x8ksTEyp+YYVI4 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06244 uniprotkb:P06244 intact:EBI-9458|uniprotkb:P11595|ensemblfungi:YJL164C|uniprotkb:D6VW23|uniprotkb:Q2VQW1 intact:EBI-9458|uniprotkb:P11595|ensemblfungi:YJL164C|uniprotkb:D6VW23|uniprotkb:Q2VQW1 psi-mi:kapa_yeast(display_long)|uniprotkb:TPK1(gene name)|psi-mi:TPK1(display_short)|uniprotkb:PKA1(gene name synonym)|uniprotkb:SRA3(gene name synonym)|uniprotkb:YJL164C(locus name)|uniprotkb:J0541(orf name)|uniprotkb:CDC25-suppressing protein kinase(gene name synonym)|uniprotkb:PK-25(gene name synonym) psi-mi:kapa_yeast(display_long)|uniprotkb:TPK1(gene name)|psi-mi:TPK1(display_short)|uniprotkb:PKA1(gene name synonym)|uniprotkb:SRA3(gene name synonym)|uniprotkb:YJL164C(locus name)|uniprotkb:J0541(orf name)|uniprotkb:CDC25-suppressing protein kinase(gene name synonym)|uniprotkb:PK-25(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320900|imex:IM-26944-329 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000785"(chromatin)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:1FOT|ensemblfungi:YJL164C(gene)|ensemblfungi:YJL164C_mRNA(transcript)|refseq:NP_012371.2|sgd:S000003700|mint:P06244|dip:DIP-548N|ensemblgenomes:YJL164C(identity) go:"GO:0000785"(chromatin)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:1FOT|ensemblfungi:YJL164C(gene)|ensemblfungi:YJL164C_mRNA(transcript)|refseq:NP_012371.2|sgd:S000003700|mint:P06244|dip:DIP-548N|ensemblgenomes:YJL164C(identity) - crc64:D4E5C30D7F11458B crc64:D4E5C30D7F11458B figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:Xz1objgQPrWVbwXt82fc/VOJxaI559292 rogid:Xz1objgQPrWVbwXt82fc/VOJxaI559292 rigid:dOM1IzST1JRIddjwyigfugivmy4 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47025 uniprotkb:P47025 intact:EBI-26032|uniprotkb:D6VW72|ensemblfungi:YJL112W intact:EBI-26032|uniprotkb:D6VW72|ensemblfungi:YJL112W psi-mi:mdv1_yeast(display_long)|uniprotkb:YJL112W(locus name)|uniprotkb:J0802(orf name)|uniprotkb:MDV1(gene name)|psi-mi:MDV1(display_short)|uniprotkb:FIS2(gene name synonym)|uniprotkb:GAG3(gene name synonym)|uniprotkb:NET2(gene name synonym)|uniprotkb:Mitochondria fission 2 protein(gene name synonym) psi-mi:mdv1_yeast(display_long)|uniprotkb:YJL112W(locus name)|uniprotkb:J0802(orf name)|uniprotkb:MDV1(gene name)|psi-mi:MDV1(display_short)|uniprotkb:FIS2(gene name synonym)|uniprotkb:GAG3(gene name synonym)|uniprotkb:NET2(gene name synonym)|uniprotkb:Mitochondria fission 2 protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320888|imex:IM-26944-393 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012423.1|sgd:S000003648|dip:DIP-1907N|ensemblfungi:YJL112W(gene)|ensemblfungi:YJL112W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021061|interpro:IPR036322|rcsb pdb:2PQN|rcsb pdb:2XU6|rcsb pdb:3UUX|rcsb pdb:5JST|ensemblgenomes:YJL112W(identity) refseq:NP_012423.1|sgd:S000003648|dip:DIP-1907N|ensemblfungi:YJL112W(gene)|ensemblfungi:YJL112W_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021061|interpro:IPR036322|rcsb pdb:2PQN|rcsb pdb:2XU6|rcsb pdb:3UUX|rcsb pdb:5JST|ensemblgenomes:YJL112W(identity) - crc64:CA8A23DBB06193A6 crc64:CA8A23DBB06193A6 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:+OUNA41DE2s5K5VZ1d6F7ZffK+M559292 rogid:+OUNA41DE2s5K5VZ1d6F7ZffK+M559292 rigid:bj+stOhTRFctx+siyYM2ZRVEVYw false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47031 uniprotkb:P47031 intact:EBI-25966|uniprotkb:D6VWA1|ensemblfungi:YJL082W intact:EBI-25966|uniprotkb:D6VWA1|ensemblfungi:YJL082W psi-mi:iml2_yeast(display_long)|uniprotkb:YJL082W(locus name)|uniprotkb:J1007(orf name)|uniprotkb:Increased minichromosome loss protein 2(gene name synonym)|uniprotkb:IML2(gene name)|psi-mi:IML2(display_short) psi-mi:iml2_yeast(display_long)|uniprotkb:YJL082W(locus name)|uniprotkb:J1007(orf name)|uniprotkb:Increased minichromosome loss protein 2(gene name synonym)|uniprotkb:IML2(gene name)|psi-mi:IML2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320876|imex:IM-26944-677 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012453.1|sgd:S000003618|mint:P47031|dip:DIP-4836N|ensemblfungi:YJL082W(gene)|ensemblfungi:YJL082W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR019412|ensemblgenomes:YJL082W(identity) refseq:NP_012453.1|sgd:S000003618|mint:P47031|dip:DIP-4836N|ensemblfungi:YJL082W(gene)|ensemblfungi:YJL082W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR019412|ensemblgenomes:YJL082W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:m/5bx9Os1exjgSh/ARBYfJiwPWo559292 rogid:m/5bx9Os1exjgSh/ARBYfJiwPWo559292 rigid:JfWrqgqaDfTl1E+tGBXIALIQ+Fs false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47035 uniprotkb:P47035 intact:EBI-25953|uniprotkb:D6VWA8|ensemblfungi:YJL076W intact:EBI-25953|uniprotkb:D6VWA8|ensemblfungi:YJL076W psi-mi:net1_yeast(display_long)|uniprotkb:YJL076W(locus name)|uniprotkb:J1038(orf name)|uniprotkb:NET1(gene name)|psi-mi:NET1(display_short)|uniprotkb:CFI1(gene name synonym)|uniprotkb:ESC5(gene name synonym)|uniprotkb:SRM8(gene name synonym) psi-mi:net1_yeast(display_long)|uniprotkb:YJL076W(locus name)|uniprotkb:J1038(orf name)|uniprotkb:NET1(gene name)|psi-mi:NET1(display_short)|uniprotkb:CFI1(gene name synonym)|uniprotkb:ESC5(gene name synonym)|uniprotkb:SRM8(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320864|imex:IM-26944-237 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012459.1|sgd:S000003612|mint:P47035|dip:DIP-5153N|ensemblfungi:YJL076W(gene)|ensemblfungi:YJL076W_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0007000"(nucleolus organization)|go:"GO:0007049"(cell cycle)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0030869"(RENT complex)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0051301"(cell division)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|interpro:IPR018844|interpro:IPR043185|ensemblgenomes:YJL076W(identity) refseq:NP_012459.1|sgd:S000003612|mint:P47035|dip:DIP-5153N|ensemblfungi:YJL076W(gene)|ensemblfungi:YJL076W_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0007000"(nucleolus organization)|go:"GO:0007049"(cell cycle)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0030869"(RENT complex)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0051301"(cell division)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|interpro:IPR018844|interpro:IPR043185|ensemblgenomes:YJL076W(identity) - crc64:80EDF9A8065EB5A2 crc64:80EDF9A8065EB5A2 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:yjUIbOfA/bCZE9nMIjYS1QTn6EI559292 rogid:yjUIbOfA/bCZE9nMIjYS1QTn6EI559292 rigid:Xfb8YNuy9nYRPFZ+1qvPRuoAW6E false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40485 uniprotkb:P40485 intact:EBI-25172|uniprotkb:D6VVI2|ensemblfungi:YIL105C intact:EBI-25172|uniprotkb:D6VVI2|ensemblfungi:YIL105C psi-mi:slm1_yeast(display_long)|uniprotkb:TORC2 effector protein SLM1(gene name synonym)|uniprotkb:Synthetic lethal with MSS4 protein 1(gene name synonym)|uniprotkb:YIL105C(locus name)|uniprotkb:SLM1(gene name)|psi-mi:SLM1(display_short)|uniprotkb:LIT2(gene name synonym) psi-mi:slm1_yeast(display_long)|uniprotkb:TORC2 effector protein SLM1(gene name synonym)|uniprotkb:Synthetic lethal with MSS4 protein 1(gene name synonym)|uniprotkb:YIL105C(locus name)|uniprotkb:SLM1(gene name)|psi-mi:SLM1(display_short)|uniprotkb:LIT2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320852|imex:IM-26944-675 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012161.1|sgd:S000001367|mint:P40485|dip:DIP-1353N|ensemblfungi:YIL105C(gene)|ensemblfungi:YIL105C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031929"(TOR signaling)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070941"(eisosome assembly)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR033191|interpro:IPR043453|rcsb pdb:3NSU|rcsb pdb:4A5K|rcsb pdb:4A6F|rcsb pdb:4A6H|rcsb pdb:4A6K|ensemblgenomes:YIL105C(identity) refseq:NP_012161.1|sgd:S000001367|mint:P40485|dip:DIP-1353N|ensemblfungi:YIL105C(gene)|ensemblfungi:YIL105C_mRNA(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031929"(TOR signaling)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070941"(eisosome assembly)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR033191|interpro:IPR043453|rcsb pdb:3NSU|rcsb pdb:4A5K|rcsb pdb:4A6F|rcsb pdb:4A6H|rcsb pdb:4A6K|ensemblgenomes:YIL105C(identity) - crc64:849C82CC0960014B crc64:849C82CC0960014B figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:f0Gtntpff7Oav37jlVaggG2VI30559292 rogid:f0Gtntpff7Oav37jlVaggG2VI30559292 rigid://ESHpGgx+QDPkROL4a34FWFETQ false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38891 uniprotkb:P38891 intact:EBI-3455|uniprotkb:D3DLF7|ensemblfungi:YHR208W intact:EBI-3455|uniprotkb:D3DLF7|ensemblfungi:YHR208W psi-mi:bca1_yeast(display_long)|uniprotkb:Protein TWT1(gene name synonym)|uniprotkb:Protein ECA39(gene name synonym)|uniprotkb:BAT1(gene name)|psi-mi:BAT1(display_short)|uniprotkb:ECA39(gene name synonym)|uniprotkb:TWT1(gene name synonym)|uniprotkb:YHR208W(locus name) psi-mi:bca1_yeast(display_long)|uniprotkb:Protein TWT1(gene name synonym)|uniprotkb:Protein ECA39(gene name synonym)|uniprotkb:BAT1(gene name)|psi-mi:BAT1(display_short)|uniprotkb:ECA39(gene name synonym)|uniprotkb:TWT1(gene name synonym)|uniprotkb:YHR208W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320840|imex:IM-26944-569 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001251|reactome:R-SCE-70895|refseq:NP_012078.3|dip:DIP-6475N|ensemblfungi:YHR208W(gene)|ensemblfungi:YHR208W_mRNA(transcript)|go:"GO:0004084"(branched-chain-amino-acid transaminase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009082"(branched-chain amino acid biosynthetic process)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0009097"(isoleucine biosynthetic process)|go:"GO:0009098"(leucine biosynthetic process)|go:"GO:0009099"(valine biosynthetic process)|go:"GO:0019509"(L-methionine salvage from methylthioadenosine)|go:"GO:0050048"("L-leucine:2-oxoglutarate aminotransferase activity")|go:"GO:0052654"(L-leucine transaminase activity)|go:"GO:0052655"(L-valine transaminase activity)|go:"GO:0052656"(L-isoleucine transaminase activity)|interpro:IPR001544(Aminotransferase, class IV)|interpro:IPR005786(Branched-chain amino acid aminotransferase II)|interpro:IPR018300|interpro:IPR033939|interpro:IPR036038|interpro:IPR043131|interpro:IPR043132|ensemblgenomes:YHR208W(identity) sgd:S000001251|reactome:R-SCE-70895|refseq:NP_012078.3|dip:DIP-6475N|ensemblfungi:YHR208W(gene)|ensemblfungi:YHR208W_mRNA(transcript)|go:"GO:0004084"(branched-chain-amino-acid transaminase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009082"(branched-chain amino acid biosynthetic process)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0009097"(isoleucine biosynthetic process)|go:"GO:0009098"(leucine biosynthetic process)|go:"GO:0009099"(valine biosynthetic process)|go:"GO:0019509"(L-methionine salvage from methylthioadenosine)|go:"GO:0050048"("L-leucine:2-oxoglutarate aminotransferase activity")|go:"GO:0052654"(L-leucine transaminase activity)|go:"GO:0052655"(L-valine transaminase activity)|go:"GO:0052656"(L-isoleucine transaminase activity)|interpro:IPR001544(Aminotransferase, class IV)|interpro:IPR005786(Branched-chain amino acid aminotransferase II)|interpro:IPR018300|interpro:IPR033939|interpro:IPR036038|interpro:IPR043131|interpro:IPR043132|ensemblgenomes:YHR208W(identity) - crc64:E76604F326A7C674 crc64:E76604F326A7C674 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:Rz/okB+egLztOJhwPzzPpl8yXlc559292 rogid:Rz/okB+egLztOJhwPzzPpl8yXlc559292 rigid:72fAVMMdHThPLGpqZG6WHbrcPcw false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23291 uniprotkb:P23291 intact:EBI-4718|uniprotkb:E9P958|uniprotkb:D3DL84|ensemblfungi:YHR135C intact:EBI-4718|uniprotkb:E9P958|uniprotkb:D3DL84|ensemblfungi:YHR135C psi-mi:kc11_yeast(display_long)|uniprotkb:YCK1(gene name)|psi-mi:YCK1(display_short)|uniprotkb:CKI2(gene name synonym)|uniprotkb:YHR135C(locus name) psi-mi:kc11_yeast(display_long)|uniprotkb:YCK1(gene name)|psi-mi:YCK1(display_short)|uniprotkb:CKI2(gene name synonym)|uniprotkb:YHR135C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320828|imex:IM-26944-327 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012003.1|sgd:S000001177|dip:DIP-719N|mint:P23291|ensemblfungi:YHR135C(gene)|ensemblfungi:YHR135C_mRNA(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0009749"(response to glucose)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:5X18|ensemblgenomes:YHR135C(identity) refseq:NP_012003.1|sgd:S000001177|dip:DIP-719N|mint:P23291|ensemblfungi:YHR135C(gene)|ensemblfungi:YHR135C_mRNA(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0009749"(response to glucose)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:5X18|ensemblgenomes:YHR135C(identity) - crc64:77344717818C2D17 crc64:77344717818C2D17 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:pFpwRNbvvNZ1NPc7VMVXSivwMeI559292 rogid:pFpwRNbvvNZ1NPc7VMVXSivwMeI559292 rigid:taehIY3O4HhsF2pDlVTdHrQd6qk false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P22140 uniprotkb:P22140 intact:EBI-6494|uniprotkb:D3DL73|ensemblfungi:YHR123W intact:EBI-6494|uniprotkb:D3DL73|ensemblfungi:YHR123W psi-mi:ept1_yeast(display_long)|uniprotkb:EPT1(gene name)|psi-mi:EPT1(display_short)|uniprotkb:Aminoalcohol phosphotransferase EPT1(gene name synonym)|uniprotkb:YHR123W(locus name) psi-mi:ept1_yeast(display_long)|uniprotkb:EPT1(gene name)|psi-mi:EPT1(display_short)|uniprotkb:Aminoalcohol phosphotransferase EPT1(gene name synonym)|uniprotkb:YHR123W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320816|imex:IM-26944-487 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011991.1|sgd:S000001165|mint:P22140|dip:DIP-5619N|ensemblfungi:YHR123W(gene)|ensemblfungi:YHR123W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004142"(diacylglycerol cholinephosphotransferase activity)|go:"GO:0004307"(ethanolaminephosphotransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006646"(phosphatidylethanolamine biosynthetic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR043130|reactome:R-SCE-1483191|reactome:R-SCE-1483213|interpro:IPR014472(Choline/ethanolaminephosphotransferase)|ensemblgenomes:YHR123W(identity) refseq:NP_011991.1|sgd:S000001165|mint:P22140|dip:DIP-5619N|ensemblfungi:YHR123W(gene)|ensemblfungi:YHR123W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004142"(diacylglycerol cholinephosphotransferase activity)|go:"GO:0004307"(ethanolaminephosphotransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006646"(phosphatidylethanolamine biosynthetic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR043130|reactome:R-SCE-1483191|reactome:R-SCE-1483213|interpro:IPR014472(Choline/ethanolaminephosphotransferase)|ensemblgenomes:YHR123W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:CWeN5fKw1tHLle/Vgn+jmL/zrQk559292 rogid:CWeN5fKw1tHLle/Vgn+jmL/zrQk559292 rigid:F0R4HnIToGEaUTj9Sr8Wfe3Bgn0 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50090 uniprotkb:P50090 intact:EBI-9630|ensemblfungi:YGR238C|uniprotkb:D6VV18 intact:EBI-9630|ensemblfungi:YGR238C|uniprotkb:D6VV18 psi-mi:kel2_yeast(display_long)|uniprotkb:KEL2(gene name)|psi-mi:KEL2(display_short)|uniprotkb:G8585(orf name)|uniprotkb:YGR238C(locus name) psi-mi:kel2_yeast(display_long)|uniprotkb:KEL2(gene name)|psi-mi:KEL2(display_short)|uniprotkb:G8585(orf name)|uniprotkb:YGR238C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320804|imex:IM-26944-567 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0090337"(regulation of formin-nucleated actin cable assembly)|go:"GO:1990615"(Kelch-containing formin regulatory complex)|interpro:IPR015915(Kelch-type beta propeller)|ensemblfungi:YGR238C(gene)|ensemblfungi:YGR238C_mRNA(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0008360"(regulation of cell shape)|refseq:NP_011754.3|sgd:S000003470|dip:DIP-4229N|mint:P50090|ensemblgenomes:YGR238C(identity) go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0043332"(mating projection tip)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0090337"(regulation of formin-nucleated actin cable assembly)|go:"GO:1990615"(Kelch-containing formin regulatory complex)|interpro:IPR015915(Kelch-type beta propeller)|ensemblfungi:YGR238C(gene)|ensemblfungi:YGR238C_mRNA(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0008360"(regulation of cell shape)|refseq:NP_011754.3|sgd:S000003470|dip:DIP-4229N|mint:P50090|ensemblgenomes:YGR238C(identity) - crc64:63B9772FF017E6D9 crc64:63B9772FF017E6D9 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:lSnioafH7gyCBHbl539AXlWBAxE559292 rogid:lSnioafH7gyCBHbl539AXlWBAxE559292 rigid:nVtcMmnS6SDlXRmITTf3LBpPLvk false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P22803 uniprotkb:P22803 intact:EBI-19598|uniprotkb:D6VUZ2|ensemblfungi:YGR209C intact:EBI-19598|uniprotkb:D6VUZ2|ensemblfungi:YGR209C psi-mi:trx2_yeast(display_long)|uniprotkb:TRX2(gene name)|psi-mi:TRX2(display_short)|uniprotkb:TRX1(gene name synonym)|uniprotkb:G7746(orf name)|uniprotkb:YGR209C(locus name)|uniprotkb:Thioredoxin II(gene name synonym)|uniprotkb:Thioredoxin-1(gene name synonym) psi-mi:trx2_yeast(display_long)|uniprotkb:TRX2(gene name)|psi-mi:TRX2(display_short)|uniprotkb:TRX1(gene name synonym)|uniprotkb:G7746(orf name)|uniprotkb:YGR209C(locus name)|uniprotkb:Thioredoxin II(gene name synonym)|uniprotkb:Thioredoxin-1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320792|imex:IM-26944-149 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003441|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0015031"(protein transport)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0080058"(protein deglutathionylation)|interpro:IPR005746(Thioredoxin)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|rcsb pdb:2FA4|rcsb pdb:2HSY|rcsb pdb:3PIN|rcsb pdb:4DSS|rcsb pdb:7BVV|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|ensemblfungi:YGR209C(gene)|ensemblfungi:YGR209C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000103"(sulfate assimilation)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006662"(glycerol ether metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|refseq:NP_011725.3|dip:DIP-5552N|mint:P22803|ensemblgenomes:YGR209C(identity) sgd:S000003441|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0015031"(protein transport)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0042144"(vacuole fusion, non-autophagic)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0080058"(protein deglutathionylation)|interpro:IPR005746(Thioredoxin)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|rcsb pdb:2FA4|rcsb pdb:2HSY|rcsb pdb:3PIN|rcsb pdb:4DSS|rcsb pdb:7BVV|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|ensemblfungi:YGR209C(gene)|ensemblfungi:YGR209C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000103"(sulfate assimilation)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006662"(glycerol ether metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|refseq:NP_011725.3|dip:DIP-5552N|mint:P22803|ensemblgenomes:YGR209C(identity) - crc64:071503762C90D451 crc64:071503762C90D451 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:pRt9fGROPXW+o4g6ynOmCDiclFk559292 rogid:pRt9fGROPXW+o4g6ynOmCDiclFk559292 rigid:U89scUPM3GxNVGFVOlP/gr4V3y0 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53283 uniprotkb:P53283 intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C intact:EBI-2044753|uniprotkb:D6VUR9|ensemblfungi:YGR138C psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:tpo2_yeast(display_long)|uniprotkb:G6417(orf name)|uniprotkb:YGR138C(locus name)|uniprotkb:TPO2(gene name)|psi-mi:TPO2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320780|imex:IM-26944-41 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259|ensemblgenomes:YGR138C(identity) refseq:NP_011654.1|sgd:S000003370|dip:DIP-7902N|mint:P53283|ensemblfungi:YGR138C(gene)|ensemblfungi:YGR138C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259|ensemblgenomes:YGR138C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 rogid:UuyY7fJHoszA44v9O9c6T54xslg559292 rigid:I+RADXNiioe8GW2QbJhBAn9WktE false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53281 uniprotkb:P53281 intact:EBI-23329|uniprotkb:D6VUR8|ensemblfungi:YGR136W intact:EBI-23329|uniprotkb:D6VUR8|ensemblfungi:YGR136W psi-mi:lsb1_yeast(display_long)|uniprotkb:LSB1(gene name)|psi-mi:LSB1(display_short)|uniprotkb:YGR136W(locus name) psi-mi:lsb1_yeast(display_long)|uniprotkb:LSB1(gene name)|psi-mi:LSB1(display_short)|uniprotkb:YGR136W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320768|imex:IM-26944-485 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011652.1|sgd:S000003368|dip:DIP-1863N|mint:P53281|ensemblfungi:YGR136W(gene)|ensemblfungi:YGR136W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030479"(actin cortical patch)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|ensemblgenomes:YGR136W(identity) refseq:NP_011652.1|sgd:S000003368|dip:DIP-1863N|mint:P53281|ensemblfungi:YGR136W(gene)|ensemblfungi:YGR136W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030479"(actin cortical patch)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|ensemblgenomes:YGR136W(identity) - crc64:5F0B1361AF84AA79 crc64:5F0B1361AF84AA79 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:R1HwHYkR6yeO64d9A2xUBxvijvU559292 rogid:R1HwHYkR6yeO64d9A2xUBxvijvU559292 rigid:6LrcEpFj4NNtWwzCUD1eWmX4T98 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P54113 uniprotkb:P54113 intact:EBI-14213|uniprotkb:E9PAG6|ensemblfungi:YLR028C|uniprotkb:D6VY30 intact:EBI-14213|uniprotkb:E9PAG6|ensemblfungi:YLR028C|uniprotkb:D6VY30 psi-mi:pur91_yeast(display_long)|uniprotkb:ADE16(gene name)|psi-mi:ADE16(display_short)|uniprotkb:YLR028C(locus name) psi-mi:pur91_yeast(display_long)|uniprotkb:ADE16(gene name)|psi-mi:ADE16(display_short)|uniprotkb:YLR028C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320948|imex:IM-26944-45 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P54113|refseq:NP_013128.1|sgd:S000004018|ensemblfungi:YLR028C(gene)|ensemblfungi:YLR028C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|interpro:IPR036914|dip:DIP-4657N|ensemblgenomes:YLR028C(identity) mint:P54113|refseq:NP_013128.1|sgd:S000004018|ensemblfungi:YLR028C(gene)|ensemblfungi:YLR028C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|interpro:IPR036914|dip:DIP-4657N|ensemblgenomes:YLR028C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:SbZvY+c2tg098pE/sezKQp+3cFE559292 rogid:SbZvY+c2tg098pE/sezKQp+3cFE559292 rigid:fj/ApC3gYy+TIZU5EZycy1vzWiQ false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06151 uniprotkb:Q06151 intact:EBI-38973|uniprotkb:Q6Q5L1|uniprotkb:D6VYR7|ensemblfungi:YLR270W intact:EBI-38973|uniprotkb:Q6Q5L1|uniprotkb:D6VYR7|ensemblfungi:YLR270W psi-mi:dcps_yeast(display_long)|uniprotkb:DCS-1(gene name synonym)|uniprotkb:Hint-related 7meGMP-directed hydrolase 1(gene name synonym)|uniprotkb:DCS1(gene name)|psi-mi:DCS1(display_short)|uniprotkb:Scavenger mRNA-decapping enzyme DcpS(gene name synonym)|uniprotkb:YLR270W(locus name)|uniprotkb:Protein Dcs1p(gene name synonym) psi-mi:dcps_yeast(display_long)|uniprotkb:DCS-1(gene name synonym)|uniprotkb:Hint-related 7meGMP-directed hydrolase 1(gene name synonym)|uniprotkb:DCS1(gene name)|psi-mi:DCS1(display_short)|uniprotkb:Scavenger mRNA-decapping enzyme DcpS(gene name synonym)|uniprotkb:YLR270W(locus name)|uniprotkb:Protein Dcs1p(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320960|imex:IM-26944-571 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013372.1|sgd:S000004260|mint:Q06151|dip:DIP-1480N|ensemblfungi:YLR270W(gene)|ensemblfungi:YLR270W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007584"(response to nutrient)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009408"(response to heat)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0031086"(nuclear-transcribed mRNA catabolic process, deadenylation-independent decay)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044692"(exoribonuclease activator activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0090342"(regulation of cell aging)|go:"GO:1901919"(positive regulation of exoribonuclease activity)|interpro:IPR008594(Scavenger mRNA decapping enzyme)|interpro:IPR011145(Scavenger mRNA decapping enzyme, N-terminal)|interpro:IPR019808|interpro:IPR036265|rcsb pdb:5BV3|rcsb pdb:6TRQ|reactome:R-SCE-429958|ensemblgenomes:YLR270W(identity) refseq:NP_013372.1|sgd:S000004260|mint:Q06151|dip:DIP-1480N|ensemblfungi:YLR270W(gene)|ensemblfungi:YLR270W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007584"(response to nutrient)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009408"(response to heat)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0031086"(nuclear-transcribed mRNA catabolic process, deadenylation-independent decay)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044692"(exoribonuclease activator activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0090342"(regulation of cell aging)|go:"GO:1901919"(positive regulation of exoribonuclease activity)|interpro:IPR008594(Scavenger mRNA decapping enzyme)|interpro:IPR011145(Scavenger mRNA decapping enzyme, N-terminal)|interpro:IPR019808|interpro:IPR036265|rcsb pdb:5BV3|rcsb pdb:6TRQ|reactome:R-SCE-429958|ensemblgenomes:YLR270W(identity) - crc64:06A57C2344A3580A crc64:06A57C2344A3580A figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:63HqohkJUuNuZVKy4HcD1f0gGCg559292 rogid:63HqohkJUuNuZVKy4HcD1f0gGCg559292 rigid:bThnkfjUbckw6kNaIq7fHdpPcfE false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50095 uniprotkb:P50095 intact:EBI-9190|ensemblfungi:YLR432W|uniprotkb:D6VZ67 intact:EBI-9190|ensemblfungi:YLR432W|uniprotkb:D6VZ67 psi-mi:imdh3_yeast(display_long)|uniprotkb:IMD3(gene name)|psi-mi:IMD3(display_short)|uniprotkb:L9753.4(orf name)|uniprotkb:YLR432W(locus name) psi-mi:imdh3_yeast(display_long)|uniprotkb:IMD3(gene name)|psi-mi:IMD3(display_short)|uniprotkb:L9753.4(orf name)|uniprotkb:YLR432W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320972|imex:IM-26944-573 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR432W(gene)|ensemblfungi:YLR432W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|reactome:R-SCE-6798695|reactome:R-SCE-73817|refseq:NP_013536.3|sgd:S000004424|dip:DIP-1947N|mint:P50095|ensemblgenomes:YLR432W(identity) ensemblfungi:YLR432W(gene)|ensemblfungi:YLR432W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|reactome:R-SCE-6798695|reactome:R-SCE-73817|refseq:NP_013536.3|sgd:S000004424|dip:DIP-1947N|mint:P50095|ensemblgenomes:YLR432W(identity) - crc64:A0C84C22527AAEA6 crc64:A0C84C22527AAEA6 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:UUEyn+zhL8Z1aasK3r/inGhtO1c559292 rogid:UUEyn+zhL8Z1aasK3r/inGhtO1c559292 rigid:0uBhaESoc+BnQCiZDKffkzcK2z0 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06205 uniprotkb:Q06205 intact:EBI-6956|uniprotkb:D6VZ83|ensemblfungi:YLR449W intact:EBI-6956|uniprotkb:D6VZ83|ensemblfungi:YLR449W psi-mi:fkbp4_yeast(display_long)|uniprotkb:FPR4(gene name)|psi-mi:FPR4(display_short)|uniprotkb:YLR449W(locus name)|uniprotkb:L9324.3(orf name)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:Histone proline isomerase(gene name synonym) psi-mi:fkbp4_yeast(display_long)|uniprotkb:FPR4(gene name)|psi-mi:FPR4(display_short)|uniprotkb:YLR449W(locus name)|uniprotkb:L9324.3(orf name)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:Histone proline isomerase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320984|imex:IM-26944-153 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004441|refseq:NP_013554.3|dip:DIP-909N|mint:Q06205|ensemblfungi:YLR449W(gene)|ensemblfungi:YLR449W_mRNA(transcript)|go:"GO:0000412"(histone peptidyl-prolyl isomerization)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR023566|interpro:IPR041232|rcsb pdb:4BF8|ensemblgenomes:YLR449W(identity) sgd:S000004441|refseq:NP_013554.3|dip:DIP-909N|mint:Q06205|ensemblfungi:YLR449W(gene)|ensemblfungi:YLR449W_mRNA(transcript)|go:"GO:0000412"(histone peptidyl-prolyl isomerization)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR023566|interpro:IPR041232|rcsb pdb:4BF8|ensemblgenomes:YLR449W(identity) - crc64:CF90C6714F04572E crc64:CF90C6714F04572E figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:rDmDSGEgRbtgkLBoJTzmzxxY7B4559292 rogid:rDmDSGEgRbtgkLBoJTzmzxxY7B4559292 rigid:TWNsb9BZAbdxxXcUiooCWiiSZKg false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P12684 uniprotkb:P12684 intact:EBI-8384|uniprotkb:E9P8X3|uniprotkb:D6VZ84|ensemblfungi:YLR450W intact:EBI-8384|uniprotkb:E9P8X3|uniprotkb:D6VZ84|ensemblfungi:YLR450W psi-mi:hmdh2_yeast(display_long)|uniprotkb:L9324.2(orf name)|uniprotkb:YLR450W(locus name)|uniprotkb:HMG2(gene name)|psi-mi:HMG2(display_short) psi-mi:hmdh2_yeast(display_long)|uniprotkb:L9324.2(orf name)|uniprotkb:YLR450W(locus name)|uniprotkb:HMG2(gene name)|psi-mi:HMG2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320996|imex:IM-26944-395 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013555.1|sgd:S000004442|mint:P12684|dip:DIP-6277N|ensemblfungi:YLR450W(gene)|ensemblfungi:YLR450W_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004420"("hydroxymethylglutaryl-CoA reductase (NADPH) activity")|go:"GO:0005635"(nuclear envelope)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008299"(isoprenoid biosynthetic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0034399"(nuclear periphery)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR002202(Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic)|interpro:IPR004554(Hydroxymethylglutaryl-CoA reductase, class I, catalytic)|interpro:IPR009023(Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding)|interpro:IPR009029(Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding)|interpro:IPR023074|interpro:IPR023076|interpro:IPR023282|interpro:IPR025583|ensemblgenomes:YLR450W(identity) refseq:NP_013555.1|sgd:S000004442|mint:P12684|dip:DIP-6277N|ensemblfungi:YLR450W(gene)|ensemblfungi:YLR450W_mRNA(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004420"("hydroxymethylglutaryl-CoA reductase (NADPH) activity")|go:"GO:0005635"(nuclear envelope)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008299"(isoprenoid biosynthetic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0034399"(nuclear periphery)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR002202(Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic)|interpro:IPR004554(Hydroxymethylglutaryl-CoA reductase, class I, catalytic)|interpro:IPR009023(Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding)|interpro:IPR009029(Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding)|interpro:IPR023074|interpro:IPR023076|interpro:IPR023282|interpro:IPR025583|ensemblgenomes:YLR450W(identity) - crc64:1FD9DCD3AC01B15E crc64:1FD9DCD3AC01B15E figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:6q1hM5csy4DSYUsSGyTr8M6b9r0559292 rogid:6q1hM5csy4DSYUsSGyTr8M6b9r0559292 rigid:R6gc+9h0Iyurm8xBDMMU9B1oGHU false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38427 uniprotkb:P38427 intact:EBI-19638|uniprotkb:D6W0I5|ensemblfungi:YML100W intact:EBI-19638|uniprotkb:D6W0I5|ensemblfungi:YML100W psi-mi:tsl1_yeast(display_long)|uniprotkb:TSL1(gene name)|psi-mi:TSL1(display_short)|uniprotkb:YML100W(locus name)|uniprotkb:Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 123 kDa subunit(gene name synonym) psi-mi:tsl1_yeast(display_long)|uniprotkb:TSL1(gene name)|psi-mi:TSL1(display_short)|uniprotkb:YML100W(locus name)|uniprotkb:Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 123 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321008|imex:IM-26944-47 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013608.1|sgd:S000004566|ensemblfungi:YML100W(gene)|ensemblfungi:YML100W_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005946"("alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)")|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0016311"(dephosphorylation)|go:"GO:0030234"(enzyme regulator activity)|interpro:IPR001830(Glycosyl transferase, family 20)|interpro:IPR003337(Trehalose-phosphatase)|interpro:IPR036412|dip:DIP-753N|mint:P38427|ensemblgenomes:YML100W(identity) refseq:NP_013608.1|sgd:S000004566|ensemblfungi:YML100W(gene)|ensemblfungi:YML100W_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005946"("alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)")|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0016311"(dephosphorylation)|go:"GO:0030234"(enzyme regulator activity)|interpro:IPR001830(Glycosyl transferase, family 20)|interpro:IPR003337(Trehalose-phosphatase)|interpro:IPR036412|dip:DIP-753N|mint:P38427|ensemblgenomes:YML100W(identity) - crc64:EA0A8A86AF178F04 crc64:EA0A8A86AF178F04 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:c83+6JC2tSJt4Z06mI3KDmHI1iM559292 rogid:c83+6JC2tSJt4Z06mI3KDmHI1iM559292 rigid:wtpStMZ4lPuX4Dd2Lx/ZTS9iQWU false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P15108 uniprotkb:P15108 intact:EBI-8666|ensemblfungi:YMR186W|uniprotkb:D6W010 intact:EBI-8666|ensemblfungi:YMR186W|uniprotkb:D6W010 psi-mi:hsc82_yeast(display_long)|uniprotkb:HSC82(gene name)|psi-mi:HSC82(display_short)|uniprotkb:YMR186W(locus name)|uniprotkb:YM8010.16(orf name)|uniprotkb:Heat shock protein Hsp90 constitutive isoform(gene name synonym)|uniprotkb:82 kDa heat shock cognate protein(gene name synonym) psi-mi:hsc82_yeast(display_long)|uniprotkb:HSC82(gene name)|psi-mi:HSC82(display_short)|uniprotkb:YMR186W(locus name)|uniprotkb:YM8010.16(orf name)|uniprotkb:Heat shock protein Hsp90 constitutive isoform(gene name synonym)|uniprotkb:82 kDa heat shock cognate protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321020|imex:IM-26944-239 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:6XLB|rcsb pdb:6XLC|rcsb pdb:6XLD|rcsb pdb:6XLE|rcsb pdb:6XLF|ensemblfungi:YMR186W(gene)|ensemblfungi:YMR186W_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000723"(telomere maintenance)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|rcsb pdb:6XLG|rcsb pdb:6XLH|reactome:R-SCE-1474151|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-9009391|refseq:NP_013911.1|sgd:S000004798|mint:P15108|dip:DIP-1524N|ensemblgenomes:YMR186W(identity) interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:6XLB|rcsb pdb:6XLC|rcsb pdb:6XLD|rcsb pdb:6XLE|rcsb pdb:6XLF|ensemblfungi:YMR186W(gene)|ensemblfungi:YMR186W_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000723"(telomere maintenance)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|rcsb pdb:6XLG|rcsb pdb:6XLH|reactome:R-SCE-1474151|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-9009391|refseq:NP_013911.1|sgd:S000004798|mint:P15108|dip:DIP-1524N|ensemblgenomes:YMR186W(identity) - crc64:DBD41524091B1F9B crc64:DBD41524091B1F9B figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:A0Na3L9N4cl7acd9lSGiwKAYK1o559292 rogid:A0Na3L9N4cl7acd9lSGiwKAYK1o559292 rigid:K1BU5a4L6j88oP1Ypzyuv5uJsKk false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P20107 uniprotkb:P20107 intact:EBI-29667|uniprotkb:D6W070|ensemblfungi:YMR243C intact:EBI-29667|uniprotkb:D6W070|ensemblfungi:YMR243C psi-mi:zrc1_yeast(display_long)|uniprotkb:ZRC1(gene name)|psi-mi:ZRC1(display_short)|uniprotkb:YM9408.05C(orf name)|uniprotkb:YMR243C(locus name) psi-mi:zrc1_yeast(display_long)|uniprotkb:ZRC1(gene name)|psi-mi:ZRC1(display_short)|uniprotkb:YM9408.05C(orf name)|uniprotkb:YMR243C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321032|imex:IM-26944-241 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013970.1|sgd:S000004856|dip:DIP-2030N|mint:P20107|ensemblfungi:YMR243C(gene)|ensemblfungi:YMR243C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|reactome:R-SCE-425410|reactome:R-SCE-435368|ensemblgenomes:YMR243C(identity) refseq:NP_013970.1|sgd:S000004856|dip:DIP-2030N|mint:P20107|ensemblfungi:YMR243C(gene)|ensemblfungi:YMR243C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|reactome:R-SCE-425410|reactome:R-SCE-435368|ensemblgenomes:YMR243C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:ZZlCJ2Xj5Hiumdl3BNStZFS9qM4559292 rogid:ZZlCJ2Xj5Hiumdl3BNStZFS9qM4559292 rigid:nhgtizWzcTvp6c7vKCFpKBFJT5U false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06208-1 uniprotkb:P06208-1 intact:EBI-21318961 intact:EBI-21318961 psi-mi:p062081(display_long)|uniprotkb:LEU4(gene name)|psi-mi:LEU4(display_short)|uniprotkb:N2173(orf name)|uniprotkb:YNL104C(locus name) psi-mi:p062081(display_long)|uniprotkb:LEU4(gene name)|psi-mi:LEU4(display_short)|uniprotkb:N2173(orf name)|uniprotkb:YNL104C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321044|imex:IM-26944-397 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P06208-1(isoform-parent)|ensemblgenomes:YNL104C(identity) uniprotkb:P06208-1(isoform-parent)|ensemblgenomes:YNL104C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:qysUHIGQ5iB9CaOQvK2/+iVHuyQ559292 rogid:qysUHIGQ5iB9CaOQvK2/+iVHuyQ559292 rigid:MQV/kskPbqv6JXMFmppJVX7Jd50 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21965 uniprotkb:P21965 intact:EBI-10517|ensemblfungi:YNL307C|uniprotkb:D6W0N8 intact:EBI-10517|ensemblfungi:YNL307C|uniprotkb:D6W0N8 psi-mi:mck1_yeast(display_long)|uniprotkb:YPK1(gene name synonym)|uniprotkb:YNL307C(locus name)|uniprotkb:N0392(orf name)|uniprotkb:MCK1(gene name)|psi-mi:MCK1(display_short)|uniprotkb:Meiosis and centromere regulatory kinase(gene name synonym) psi-mi:mck1_yeast(display_long)|uniprotkb:YPK1(gene name synonym)|uniprotkb:YNL307C(locus name)|uniprotkb:N0392(orf name)|uniprotkb:MCK1(gene name)|psi-mi:MCK1(display_short)|uniprotkb:Meiosis and centromere regulatory kinase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321056|imex:IM-26944-679 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014092.1|sgd:S000005251|ensemblfungi:YNL307C(gene)|ensemblfungi:YNL307C_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030332"(cyclin binding)|go:"GO:0030437"(ascospore formation)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0071472"(cellular response to salt stress)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039192|reactome:R-SCE-3371453|go:"GO:0034605"(cellular response to heat)|mint:P21965|dip:DIP-5860N|ensemblgenomes:YNL307C(identity) refseq:NP_014092.1|sgd:S000005251|ensemblfungi:YNL307C(gene)|ensemblfungi:YNL307C_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030332"(cyclin binding)|go:"GO:0030437"(ascospore formation)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0071472"(cellular response to salt stress)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039192|reactome:R-SCE-3371453|go:"GO:0034605"(cellular response to heat)|mint:P21965|dip:DIP-5860N|ensemblgenomes:YNL307C(identity) - crc64:BCF0C776B6E3841B crc64:BCF0C776B6E3841B figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:smRz/MIn0un4L+VS7nVGNMe0/0E559292 rogid:smRz/MIn0un4L+VS7nVGNMe0/0E559292 rigid:j+0c2HXsCD+psDxNjL2M4mpAyW0 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06634 uniprotkb:P06634 intact:EBI-5744|uniprotkb:D6W2R0|ensemblfungi:YOR204W intact:EBI-5744|uniprotkb:D6W2R0|ensemblfungi:YOR204W psi-mi:ded1_yeast(display_long)|uniprotkb:DED1(gene name)|psi-mi:DED1(display_short)|uniprotkb:SPP81(gene name synonym)|uniprotkb:YOR204W(locus name)|uniprotkb:DEAD box protein 1(gene name synonym) psi-mi:ded1_yeast(display_long)|uniprotkb:DED1(gene name)|psi-mi:DED1(display_short)|uniprotkb:SPP81(gene name synonym)|uniprotkb:YOR204W(locus name)|uniprotkb:DEAD box protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321068|imex:IM-26944-399 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005730|refseq:NP_014847.3|dip:DIP-5820N|mint:P06634|ensemblfungi:YOR204W(gene)|ensemblfungi:YOR204W_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044763|reactome:R-SCE-6798695|ensemblgenomes:YOR204W(identity) sgd:S000005730|refseq:NP_014847.3|dip:DIP-5820N|mint:P06634|ensemblfungi:YOR204W(gene)|ensemblfungi:YOR204W_mRNA(transcript)|go:"GO:0000390"(spliceosomal complex disassembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044763|reactome:R-SCE-6798695|ensemblgenomes:YOR204W(identity) - crc64:B6722D94C03BFA4B crc64:B6722D94C03BFA4B figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:FkldumX6m5gBuuaG09aTJ0kuMZM559292 rogid:FkldumX6m5gBuuaG09aTJ0kuMZM559292 rigid:BaKSLgxrJJ28NdM/GZ4sPLk4Yw4 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04651 uniprotkb:Q04651 intact:EBI-27850|uniprotkb:E9PAD9|uniprotkb:D6VZA6|ensemblfungi:YML067C intact:EBI-27850|uniprotkb:E9PAD9|uniprotkb:D6VZA6|ensemblfungi:YML067C psi-mi:erv41_yeast(display_long)|uniprotkb:YML067C(locus name)|uniprotkb:ERV41(gene name)|psi-mi:ERV41(display_short) psi-mi:erv41_yeast(display_long)|uniprotkb:YML067C(locus name)|uniprotkb:ERV41(gene name)|psi-mi:ERV41(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321080|imex:IM-26944-243 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013644.1|sgd:S000004532|dip:DIP-6791N|mint:Q04651|ensemblfungi:YML067C(gene)|ensemblfungi:YML067C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542|rcsb pdb:3ZLC|ensemblgenomes:YML067C(identity) refseq:NP_013644.1|sgd:S000004532|dip:DIP-6791N|mint:Q04651|ensemblfungi:YML067C(gene)|ensemblfungi:YML067C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR012936(Protein of unknown function DUF1692)|interpro:IPR039542|rcsb pdb:3ZLC|ensemblgenomes:YML067C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:IpGpvBxckHz1ExXTnTsKEHU2su8559292 rogid:IpGpvBxckHz1ExXTnTsKEHU2su8559292 rigid:asEMriC0Q7TwsJO370qWf+LLicA false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17106 uniprotkb:P17106 intact:EBI-4096|uniprotkb:Q6Q5N1|uniprotkb:P17623|uniprotkb:D6VWN1|ensemblfungi:YJR060W intact:EBI-4096|uniprotkb:Q6Q5N1|uniprotkb:P17623|uniprotkb:D6VWN1|ensemblfungi:YJR060W psi-mi:cbf1_yeast(display_long)|uniprotkb:CEP1(gene name synonym)|uniprotkb:CP1(gene name synonym)|uniprotkb:CPF1(gene name synonym)|uniprotkb:J1730(orf name)|uniprotkb:YJR060W(locus name)|uniprotkb:CBF1(gene name)|psi-mi:CBF1(display_short)|uniprotkb:Centromere-binding factor 1(gene name synonym)|uniprotkb:Centromere promoter factor 1(gene name synonym) psi-mi:cbf1_yeast(display_long)|uniprotkb:CEP1(gene name synonym)|uniprotkb:CP1(gene name synonym)|uniprotkb:CPF1(gene name synonym)|uniprotkb:J1730(orf name)|uniprotkb:YJR060W(locus name)|uniprotkb:CBF1(gene name)|psi-mi:CBF1(display_short)|uniprotkb:Centromere-binding factor 1(gene name synonym)|uniprotkb:Centromere promoter factor 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321092|imex:IM-26944-49 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012594.1|sgd:S000003821|dip:DIP-2239N|mint:P17106|ensemblfungi:YJR060W(gene)|ensemblfungi:YJR060W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0089713"(Cbf1-Met4-Met28 complex)|go:"GO:0098781"(ncRNA transcription)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblgenomes:YJR060W(identity) refseq:NP_012594.1|sgd:S000003821|dip:DIP-2239N|mint:P17106|ensemblfungi:YJR060W(gene)|ensemblfungi:YJR060W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0089713"(Cbf1-Met4-Met28 complex)|go:"GO:0098781"(ncRNA transcription)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|ensemblgenomes:YJR060W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:SjrIzQ9f1rrxeycid/060/5MRY8559292 rogid:SjrIzQ9f1rrxeycid/060/5MRY8559292 rigid:d97uN/P9WUplrtc33d86FwZMaoE false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P04806 uniprotkb:P04806 intact:EBI-8732|ensemblfungi:YFR053C|uniprotkb:D6VTT6 intact:EBI-8732|ensemblfungi:YFR053C|uniprotkb:D6VTT6 psi-mi:hxka_yeast(display_long)|uniprotkb:HKA(gene name synonym)|uniprotkb:YFR053C(locus name)|uniprotkb:HXK1(gene name)|psi-mi:HXK1(display_short)|uniprotkb:Hexokinase-A(gene name synonym)|uniprotkb:Hexokinase PI(gene name synonym) psi-mi:hxka_yeast(display_long)|uniprotkb:HKA(gene name synonym)|uniprotkb:YFR053C(locus name)|uniprotkb:HXK1(gene name)|psi-mi:HXK1(display_short)|uniprotkb:Hexokinase-A(gene name synonym)|uniprotkb:Hexokinase PI(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320708|imex:IM-26944-233 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YFR053C(gene)|ensemblfungi:YFR053C_mRNA(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0004340"(glucokinase activity)|go:"GO:0004396"(hexokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005536"(glucose binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006013"(mannose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008865"(fructokinase activity)|go:"GO:0019158"(mannokinase activity)|go:"GO:0032445"(fructose import)|go:"GO:0046323"(glucose import)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|interpro:IPR001312(Hexokinase)|interpro:IPR019807|interpro:IPR022672|interpro:IPR022673|interpro:IPR043129|rcsb pdb:1HKG|rcsb pdb:3B8A|reactome:R-SCE-170822|reactome:R-SCE-6798695|reactome:R-SCE-70171|refseq:NP_116711.3|sgd:S000001949|mint:P04806|dip:DIP-5377N|ensemblgenomes:YFR053C(identity) ensemblfungi:YFR053C(gene)|ensemblfungi:YFR053C_mRNA(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0004340"(glucokinase activity)|go:"GO:0004396"(hexokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005536"(glucose binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006013"(mannose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008865"(fructokinase activity)|go:"GO:0019158"(mannokinase activity)|go:"GO:0032445"(fructose import)|go:"GO:0046323"(glucose import)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|interpro:IPR001312(Hexokinase)|interpro:IPR019807|interpro:IPR022672|interpro:IPR022673|interpro:IPR043129|rcsb pdb:1HKG|rcsb pdb:3B8A|reactome:R-SCE-170822|reactome:R-SCE-6798695|reactome:R-SCE-70171|refseq:NP_116711.3|sgd:S000001949|mint:P04806|dip:DIP-5377N|ensemblgenomes:YFR053C(identity) - crc64:AF5C9DA8F17BC3D0 crc64:AF5C9DA8F17BC3D0 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:zsmpb9CuEStI8OqnH/VF1X/c40A559292 rogid:zsmpb9CuEStI8OqnH/VF1X/c40A559292 rigid:XUX18i4++ZGTopxAshKGIb0xAig false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53203 uniprotkb:P53203 intact:EBI-23069|uniprotkb:D6VUE1|ensemblfungi:YGR004W intact:EBI-23069|uniprotkb:D6VUE1|ensemblfungi:YGR004W psi-mi:pex31_yeast(display_long)|uniprotkb:Peroxin-31(gene name synonym)|uniprotkb:PEX31(gene name)|psi-mi:PEX31(display_short)|uniprotkb:YGR004W(locus name) psi-mi:pex31_yeast(display_long)|uniprotkb:Peroxin-31(gene name synonym)|uniprotkb:PEX31(gene name)|psi-mi:PEX31(display_short)|uniprotkb:YGR004W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320720|imex:IM-26944-235 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011518.1|sgd:S000003236|dip:DIP-5455N|ensemblfungi:YGR004W(gene)|ensemblfungi:YGR004W_mRNA(transcript)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007031"(peroxisome organization)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071944"(cell periphery)|go:"GO:0097749"(membrane tubulation)|go:"GO:1900063"(regulation of peroxisome organization)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR010482(Integral peroxisomal membrane peroxin)|ensemblgenomes:YGR004W(identity) refseq:NP_011518.1|sgd:S000003236|dip:DIP-5455N|ensemblfungi:YGR004W(gene)|ensemblfungi:YGR004W_mRNA(transcript)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007031"(peroxisome organization)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071944"(cell periphery)|go:"GO:0097749"(membrane tubulation)|go:"GO:1900063"(regulation of peroxisome organization)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR010482(Integral peroxisomal membrane peroxin)|ensemblgenomes:YGR004W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:A8m6e08wcV/TdPj9ks1r34U8G80559292 rogid:A8m6e08wcV/TdPj9ks1r34U8G80559292 rigid:c2Pg9WZ+mjIoRpcZZqwycEB2AJo false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40260 uniprotkb:P40260 intact:EBI-10714|ensemblfungi:YGR121C|uniprotkb:D6VUQ2 intact:EBI-10714|ensemblfungi:YGR121C|uniprotkb:D6VUQ2 psi-mi:mep1_yeast(display_long)|uniprotkb:MEP1(gene name)|psi-mi:MEP1(display_short)|uniprotkb:YGR121C(locus name)|uniprotkb:G6331(orf name)|uniprotkb:AMT1(gene name synonym) psi-mi:mep1_yeast(display_long)|uniprotkb:MEP1(gene name)|psi-mi:MEP1(display_short)|uniprotkb:YGR121C(locus name)|uniprotkb:G6331(orf name)|uniprotkb:AMT1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320756|imex:IM-26944-673 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR121C(gene)|ensemblfungi:YGR121C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|sgd:S000003353|refseq:NP_011636.3|mint:P40260|dip:DIP-5530N|ensemblgenomes:YGR121C(identity) ensemblfungi:YGR121C(gene)|ensemblfungi:YGR121C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|sgd:S000003353|refseq:NP_011636.3|mint:P40260|dip:DIP-5530N|ensemblgenomes:YGR121C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:VnoBl5jhQD24N0SbCLv68HCwl1U559292 rogid:VnoBl5jhQD24N0SbCLv68HCwl1U559292 rigid:zGJ3NHQkvmYeYIDPX6Oxhs5ln1Q false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53224 uniprotkb:P53224 intact:EBI-12592|uniprotkb:D6VUH5|ensemblfungi:YGR038W intact:EBI-12592|uniprotkb:D6VUH5|ensemblfungi:YGR038W psi-mi:orm1_yeast(display_long)|uniprotkb:YGR038W(locus name)|uniprotkb:ORM1(gene name)|psi-mi:ORM1(display_short) psi-mi:orm1_yeast(display_long)|uniprotkb:YGR038W(locus name)|uniprotkb:ORM1(gene name)|psi-mi:ORM1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320744|imex:IM-26944-391 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR038W(gene)|ensemblfungi:YGR038W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|refseq:NP_011552.1|sgd:S000003270|reactome:R-SCE-6798695|dip:DIP-8124N|ensemblgenomes:YGR038W(identity) ensemblfungi:YGR038W(gene)|ensemblfungi:YGR038W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|refseq:NP_011552.1|sgd:S000003270|reactome:R-SCE-6798695|dip:DIP-8124N|ensemblgenomes:YGR038W(identity) - crc64:4387D00ACE4F3A1D crc64:4387D00ACE4F3A1D figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:HsbGN/V/sSXpez8xOIDmVo6oiSk559292 rogid:HsbGN/V/sSXpez8xOIDmVo6oiSk559292 rigid:woEBw3Hlm4Dj+EHFfOFwS/sGLiA false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53204 uniprotkb:P53204 intact:EBI-23073|uniprotkb:D6VUE7|ensemblfungi:YGR010W intact:EBI-23073|uniprotkb:D6VUE7|ensemblfungi:YGR010W psi-mi:nma2_yeast(display_long)|uniprotkb:NMA2(gene name)|psi-mi:NMA2(display_short)|uniprotkb:"NAD(+) pyrophosphorylase 2"(gene name synonym)|uniprotkb:"NAD(+) diphosphorylase 2"(gene name synonym)|uniprotkb:Nicotinamide-nucleotide adenylyltransferase 2(gene name synonym)|uniprotkb:Nicotinate-nucleotide adenylyltransferase 2(gene name synonym)|uniprotkb:YGR010W(locus name) psi-mi:nma2_yeast(display_long)|uniprotkb:NMA2(gene name)|psi-mi:NMA2(display_short)|uniprotkb:"NAD(+) pyrophosphorylase 2"(gene name synonym)|uniprotkb:"NAD(+) diphosphorylase 2"(gene name synonym)|uniprotkb:Nicotinamide-nucleotide adenylyltransferase 2(gene name synonym)|uniprotkb:Nicotinate-nucleotide adenylyltransferase 2(gene name synonym)|uniprotkb:YGR010W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21320732|imex:IM-26944-671 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011524.1|sgd:S000003242|dip:DIP-1227N|mint:P53204|ensemblfungi:YGR010W(gene)|ensemblfungi:YGR010W_mRNA(transcript)|go:"GO:0000309"(nicotinamide-nucleotide adenylyltransferase activity)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0009435"(NAD biosynthetic process)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|reactome:R-SCE-196807|ensemblgenomes:YGR010W(identity) refseq:NP_011524.1|sgd:S000003242|dip:DIP-1227N|mint:P53204|ensemblfungi:YGR010W(gene)|ensemblfungi:YGR010W_mRNA(transcript)|go:"GO:0000309"(nicotinamide-nucleotide adenylyltransferase activity)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0009435"(NAD biosynthetic process)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|reactome:R-SCE-196807|ensemblgenomes:YGR010W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:AdSZgVYoChR4aYSPC7gsAQ5Pws0559292 rogid:AdSZgVYoChR4aYSPC7gsAQ5Pws0559292 rigid:o7N4J7UIQeLHyfpb31v4uxlaebE false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q00582 uniprotkb:Q00582 intact:EBI-7954|uniprotkb:D6W0G3|ensemblfungi:YML121W intact:EBI-7954|uniprotkb:D6W0G3|ensemblfungi:YML121W psi-mi:gtr1_yeast(display_long)|uniprotkb:YM7056.05(orf name)|uniprotkb:YML121W(locus name)|uniprotkb:GTR1(gene name)|psi-mi:GTR1(display_short) psi-mi:gtr1_yeast(display_long)|uniprotkb:YM7056.05(orf name)|uniprotkb:YML121W(locus name)|uniprotkb:GTR1(gene name)|psi-mi:GTR1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321399|imex:IM-26944-497 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013585.1|sgd:S000004590|mint:Q00582|dip:DIP-1358N|ensemblfungi:YML121W(gene)|ensemblfungi:YML121W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006348"|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990131"(Gtr1-Gtr2 GTPase complex)|interpro:IPR006762(Gtr1/RagA G protein)|interpro:IPR027417|interpro:IPR039397|rcsb pdb:3R7W|rcsb pdb:4ARZ|rcsb pdb:6JWP|reactome:R-SCE-165159|reactome:R-SCE-9639288|ensemblgenomes:YML121W(identity) refseq:NP_013585.1|sgd:S000004590|mint:Q00582|dip:DIP-1358N|ensemblfungi:YML121W(gene)|ensemblfungi:YML121W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006348"|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006817"(phosphate ion transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990131"(Gtr1-Gtr2 GTPase complex)|interpro:IPR006762(Gtr1/RagA G protein)|interpro:IPR027417|interpro:IPR039397|rcsb pdb:3R7W|rcsb pdb:4ARZ|rcsb pdb:6JWP|reactome:R-SCE-165159|reactome:R-SCE-9639288|ensemblgenomes:YML121W(identity) - crc64:B79CE7FE7AD2FDBE crc64:B79CE7FE7AD2FDBE figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:5LJU5zMF4NDDY9Bmndu0Q+JIm54559292 rogid:5LJU5zMF4NDDY9Bmndu0Q+JIm54559292 rigid:KjSw0W1AN3DYfR8cXCDDj2wlcYY false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41948 uniprotkb:P41948 intact:EBI-10721|ensemblfungi:YNL142W|uniprotkb:D6W140 intact:EBI-10721|ensemblfungi:YNL142W|uniprotkb:D6W140 psi-mi:mep2_yeast(display_long)|uniprotkb:MEP2(gene name)|psi-mi:MEP2(display_short)|uniprotkb:YNL142W(locus name)|uniprotkb:N1207(orf name)|uniprotkb:N1820(orf name)|uniprotkb:AMT2(gene name synonym) psi-mi:mep2_yeast(display_long)|uniprotkb:MEP2(gene name)|psi-mi:MEP2(display_short)|uniprotkb:YNL142W(locus name)|uniprotkb:N1207(orf name)|uniprotkb:N1820(orf name)|uniprotkb:AMT2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321387|imex:IM-26944-685 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL142W(gene)|ensemblfungi:YNL142W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|go:"GO:1900430"(positive regulation of filamentous growth of a population of unicellular organisms)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|rcsb pdb:5AEX|refseq:NP_014257.1|sgd:S000005086|dip:DIP-4340N|ensemblgenomes:YNL142W(identity) ensemblfungi:YNL142W(gene)|ensemblfungi:YNL142W_mRNA(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|go:"GO:1900430"(positive regulation of filamentous growth of a population of unicellular organisms)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|rcsb pdb:5AEX|refseq:NP_014257.1|sgd:S000005086|dip:DIP-4340N|ensemblgenomes:YNL142W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:3UqhhEzAfYLfblLgaIyu9opa9RI559292 rogid:3UqhhEzAfYLfblLgaIyu9opa9RI559292 rigid:sOrpnwmeqqE/qi0MWi3cbS+5DF4 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06103 uniprotkb:P06103 intact:EBI-8973|ensemblfungi:YOR361C|uniprotkb:D6W356 intact:EBI-8973|ensemblfungi:YOR361C|uniprotkb:D6W356 psi-mi:eif3b_yeast(display_long)|uniprotkb:YOR361C(locus name)|uniprotkb:PRT1(gene name)|psi-mi:PRT1(display_short)|uniprotkb:CDC63(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 90 kDa subunit(gene name synonym)|uniprotkb:Translation initiation factor eIF3 p90 subunit(gene name synonym)|uniprotkb:Cell cycle regulation and translation initiation protein(gene name synonym) psi-mi:eif3b_yeast(display_long)|uniprotkb:YOR361C(locus name)|uniprotkb:PRT1(gene name)|psi-mi:PRT1(display_short)|uniprotkb:CDC63(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 90 kDa subunit(gene name synonym)|uniprotkb:Translation initiation factor eIF3 p90 subunit(gene name synonym)|uniprotkb:Cell cycle regulation and translation initiation protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321375|imex:IM-26944-255 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR361C(gene)|ensemblfungi:YOR361C_mRNA(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043614"(multi-eIF complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR011400(Translation initiation factor eIF-3b)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR034363|interpro:IPR035979|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:3NS5|rcsb pdb:3NS6|rcsb pdb:3ZWL|rcsb pdb:4U1E|rcsb pdb:4U1F|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6ZCE|rcsb pdb:6ZU9|reactome:R-SCE-156827|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|refseq:NP_015006.3|sgd:S000005888|mint:P06103|dip:DIP-2519N|ensemblgenomes:YOR361C(identity) ensemblfungi:YOR361C(gene)|ensemblfungi:YOR361C_mRNA(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043614"(multi-eIF complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR011400(Translation initiation factor eIF-3b)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR034363|interpro:IPR035979|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:3NS5|rcsb pdb:3NS6|rcsb pdb:3ZWL|rcsb pdb:4U1E|rcsb pdb:4U1F|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6ZCE|rcsb pdb:6ZU9|reactome:R-SCE-156827|reactome:R-SCE-72649|reactome:R-SCE-72695|reactome:R-SCE-72702|refseq:NP_015006.3|sgd:S000005888|mint:P06103|dip:DIP-2519N|ensemblgenomes:YOR361C(identity) - crc64:F5E4E783408EE948 crc64:F5E4E783408EE948 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:KeOY80g2TW3axiQNc1iJhsqEUPM559292 rogid:KeOY80g2TW3axiQNc1iJhsqEUPM559292 rigid:TW5wG9L6s6Ju+I4KW4/vTkGqAM0 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12236 uniprotkb:Q12236 intact:EBI-9844|intact:EBI-2935811|uniprotkb:D6W1W8|ensemblfungi:YOL100W intact:EBI-9844|intact:EBI-2935811|uniprotkb:D6W1W8|ensemblfungi:YOL100W psi-mi:pkh2_yeast(display_long)|uniprotkb:YOL100W(locus name)|uniprotkb:HRC1081(orf name)|uniprotkb:PKH2(gene name)|psi-mi:PKH2(display_short)|uniprotkb:PKB-activating kinase homolog 2(gene name synonym) psi-mi:pkh2_yeast(display_long)|uniprotkb:YOL100W(locus name)|uniprotkb:HRC1081(orf name)|uniprotkb:PKH2(gene name)|psi-mi:PKH2(display_short)|uniprotkb:PKB-activating kinase homolog 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321363|imex:IM-26944-253 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014541.1|sgd:S000005460|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0060211"("regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|ensemblfungi:YOL100W(gene)|ensemblfungi:YOL100W_mRNA(transcript)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039046|reactome:R-SCE-114604|reactome:R-SCE-1257604|reactome:R-SCE-165158|reactome:R-SCE-202424|reactome:R-SCE-2730905|reactome:R-SCE-389357|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0004672"(protein kinase activity)|reactome:R-SCE-392451|reactome:R-SCE-5218920|reactome:R-SCE-5218921|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-6804757|reactome:R-SCE-9634635|reactome:R-SCE-5625740|dip:DIP-6295N|mint:Q12236|ensemblgenomes:YOL100W(identity) refseq:NP_014541.1|sgd:S000005460|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0060211"("regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|ensemblfungi:YOL100W(gene)|ensemblfungi:YOL100W_mRNA(transcript)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039046|reactome:R-SCE-114604|reactome:R-SCE-1257604|reactome:R-SCE-165158|reactome:R-SCE-202424|reactome:R-SCE-2730905|reactome:R-SCE-389357|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0004672"(protein kinase activity)|reactome:R-SCE-392451|reactome:R-SCE-5218920|reactome:R-SCE-5218921|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-6804757|reactome:R-SCE-9634635|reactome:R-SCE-5625740|dip:DIP-6295N|mint:Q12236|ensemblgenomes:YOL100W(identity) - crc64:BE0DD9D49AC2EBC3 crc64:BE0DD9D49AC2EBC3 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:KzJ+WGY+PylRDsK1olfak8IyuXM559292 rogid:KzJ+WGY+PylRDsK1olfak8IyuXM559292 rigid:ed169Tf6LtB2nLKWzbLxDRQdPiY false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40462 uniprotkb:P40462 intact:EBI-25239|uniprotkb:D6VVE9|ensemblfungi:YIL137C intact:EBI-25239|uniprotkb:D6VVE9|ensemblfungi:YIL137C psi-mi:tm108_yeast(display_long)|uniprotkb:YIL137C(locus name)|uniprotkb:TMA108(gene name)|psi-mi:TMA108(display_short)|uniprotkb:108 kDa translation machinery-associated protein(gene name synonym) psi-mi:tm108_yeast(display_long)|uniprotkb:YIL137C(locus name)|uniprotkb:TMA108(gene name)|psi-mi:TMA108(display_short)|uniprotkb:108 kDa translation machinery-associated protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321435|imex:IM-26944-159 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012129.1|sgd:S000001399|mint:P40462|dip:DIP-5097N|ensemblfungi:YIL137C(gene)|ensemblfungi:YIL137C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0006508"(proteolysis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042277"(peptide binding)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:1990593"(nascent polypeptide-associated complex binding)|go:"GO:2000765"(regulation of cytoplasmic translation)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR024571|interpro:IPR027268|interpro:IPR033514|interpro:IPR034016|interpro:IPR042097|reactome:R-SCE-6798695|reactome:R-SCE-983168|reactome:R-SCE-983170|ensemblgenomes:YIL137C(identity) refseq:NP_012129.1|sgd:S000001399|mint:P40462|dip:DIP-5097N|ensemblfungi:YIL137C(gene)|ensemblfungi:YIL137C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0006508"(proteolysis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042277"(peptide binding)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:1990593"(nascent polypeptide-associated complex binding)|go:"GO:2000765"(regulation of cytoplasmic translation)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR024571|interpro:IPR027268|interpro:IPR033514|interpro:IPR034016|interpro:IPR042097|reactome:R-SCE-6798695|reactome:R-SCE-983168|reactome:R-SCE-983170|ensemblgenomes:YIL137C(identity) - crc64:E14B79A6F6D89F4F crc64:E14B79A6F6D89F4F figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:vu+ys28+XWhpqz6OXE7I6WOiydo559292 rogid:vu+ys28+XWhpqz6OXE7I6WOiydo559292 rigid:CRyuEgBlJupCKBBKgexiuRgpfrM false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P16862 uniprotkb:P16862 intact:EBI-9435|ensemblfungi:YMR205C|uniprotkb:D6W030 intact:EBI-9435|ensemblfungi:YMR205C|uniprotkb:D6W030 psi-mi:pfka2_yeast(display_long)|uniprotkb:PFK2(gene name)|psi-mi:PFK2(display_short)|uniprotkb:YMR205C(locus name)|uniprotkb:YM8325.06C(orf name)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:ATP-dependent 6-phosphofructokinase(gene name synonym) psi-mi:pfka2_yeast(display_long)|uniprotkb:PFK2(gene name)|psi-mi:PFK2(display_short)|uniprotkb:YMR205C(locus name)|uniprotkb:YM8325.06C(orf name)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:ATP-dependent 6-phosphofructokinase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321423|imex:IM-26944-335 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YMR205C(gene)|ensemblfungi:YMR205C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005945"(6-phosphofructokinase complex)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016208"(AMP binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070072"(vacuolar proton-transporting V-type ATPase complex assembly)|go:"GO:0070095"(fructose-6-phosphate binding)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000023(Phosphofructokinase)|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR022953|interpro:IPR029068|interpro:IPR035966|rcsb pdb:3O8O|reactome:R-SCE-6798695|reactome:R-SCE-70171|refseq:NP_013932.1|sgd:S000004818|mint:P16862|dip:DIP-2619N|ensemblgenomes:YMR205C(identity) ensemblfungi:YMR205C(gene)|ensemblfungi:YMR205C_mRNA(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005945"(6-phosphofructokinase complex)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016208"(AMP binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070072"(vacuolar proton-transporting V-type ATPase complex assembly)|go:"GO:0070095"(fructose-6-phosphate binding)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000023(Phosphofructokinase)|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR022953|interpro:IPR029068|interpro:IPR035966|rcsb pdb:3O8O|reactome:R-SCE-6798695|reactome:R-SCE-70171|refseq:NP_013932.1|sgd:S000004818|mint:P16862|dip:DIP-2619N|ensemblgenomes:YMR205C(identity) - crc64:82CE6402CEDBBCB2 crc64:82CE6402CEDBBCB2 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:PurR+sy8cBMAoGxl0dMMcxuz8wI559292 rogid:PurR+sy8cBMAoGxl0dMMcxuz8wI559292 rigid:FjYtAyptZVO1MfOMyGVJAKzoRaE false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47129 uniprotkb:P47129 intact:EBI-25556|uniprotkb:D6VWQ2|ensemblfungi:YJR083C intact:EBI-25556|uniprotkb:D6VWQ2|ensemblfungi:YJR083C psi-mi:acf4_yeast(display_long)|uniprotkb:ACF4(gene name)|psi-mi:ACF4(display_short)|uniprotkb:J1857(orf name)|uniprotkb:YJR083C(locus name) psi-mi:acf4_yeast(display_long)|uniprotkb:ACF4(gene name)|psi-mi:ACF4(display_short)|uniprotkb:J1857(orf name)|uniprotkb:YJR083C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321411|imex:IM-26944-157 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003843|refseq:NP_012616.1|dip:DIP-2890N|ensemblfungi:YJR083C(gene)|ensemblfungi:YJR083C_mRNA(transcript)|ensemblgenomes:YJR083C(identity) sgd:S000003843|refseq:NP_012616.1|dip:DIP-2890N|ensemblfungi:YJR083C(gene)|ensemblfungi:YJR083C_mRNA(transcript)|ensemblgenomes:YJR083C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:67kz2WXharaG1wxiEduByuaYYLU559292 rogid:67kz2WXharaG1wxiEduByuaYYLU559292 rigid:gdViNf7OLalzlWnbWXrj00Piz3A false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23900 uniprotkb:P23900 intact:EBI-7074|uniprotkb:D6VXW3|ensemblfungi:YLL043W intact:EBI-7074|uniprotkb:D6VXW3|ensemblfungi:YLL043W psi-mi:fps1_yeast(display_long)|uniprotkb:YLL043W(locus name)|uniprotkb:FPS1(gene name)|psi-mi:FPS1(display_short) psi-mi:fps1_yeast(display_long)|uniprotkb:YLL043W(locus name)|uniprotkb:FPS1(gene name)|psi-mi:FPS1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321351|imex:IM-26944-251 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013057.1|sgd:S000003966|dip:DIP-3979N|mint:P23900|ensemblfungi:YLL043W(gene)|ensemblfungi:YLL043W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006071"(glycerol metabolic process)|go:"GO:0006846"(acetate transport)|go:"GO:0015168"(glycerol transmembrane transporter activity)|go:"GO:0015254"(glycerol channel activity)|go:"GO:0015700"(arsenite transport)|go:"GO:0015791"(polyol transport)|go:"GO:0015793"(glycerol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR000425(Major intrinsic protein)|interpro:IPR022357|interpro:IPR023271|reactome:R-SCE-432030|reactome:R-SCE-432040|reactome:R-SCE-432047|ensemblgenomes:YLL043W(identity) refseq:NP_013057.1|sgd:S000003966|dip:DIP-3979N|mint:P23900|ensemblfungi:YLL043W(gene)|ensemblfungi:YLL043W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006071"(glycerol metabolic process)|go:"GO:0006846"(acetate transport)|go:"GO:0015168"(glycerol transmembrane transporter activity)|go:"GO:0015254"(glycerol channel activity)|go:"GO:0015700"(arsenite transport)|go:"GO:0015791"(polyol transport)|go:"GO:0015793"(glycerol transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|interpro:IPR000425(Major intrinsic protein)|interpro:IPR022357|interpro:IPR023271|reactome:R-SCE-432030|reactome:R-SCE-432040|reactome:R-SCE-432047|ensemblgenomes:YLL043W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:cpETK9YeU5MA32QUqe9ZeCqJfqE559292 rogid:cpETK9YeU5MA32QUqe9ZeCqJfqE559292 rigid:8SMWudEE0SQ/HM6PIXAhnkofVyQ false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P41921-1 uniprotkb:P41921-1 intact:EBI-21321332 intact:EBI-21321332 psi-mi:p419211(display_long)|uniprotkb:GLR1(gene name)|psi-mi:GLR1(display_short)|uniprotkb:LPG17W(orf name)|uniprotkb:YPL091W(locus name) psi-mi:p419211(display_long)|uniprotkb:GLR1(gene name)|psi-mi:GLR1(display_short)|uniprotkb:LPG17W(orf name)|uniprotkb:YPL091W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321339|imex:IM-26944-495 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:P41921-1(isoform-parent)|ensemblgenomes:YPL091W(identity) uniprotkb:P41921-1(isoform-parent)|ensemblgenomes:YPL091W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:1+gFQ2Tbb89fNCsx7f6JlP5VLBA559292 rogid:1+gFQ2Tbb89fNCsx7f6JlP5VLBA559292 rigid:aKvJZPknWUSypJJYIqW0rd1Q+EE false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23585 uniprotkb:P23585 intact:EBI-2054100|uniprotkb:D6VZI5|ensemblfungi:YMR011W intact:EBI-2054100|uniprotkb:D6VZI5|ensemblfungi:YMR011W psi-mi:hxt2_yeast(display_long)|uniprotkb:YM8270.15(orf name)|uniprotkb:YMR011W(locus name)|uniprotkb:HXT2(gene name)|psi-mi:HXT2(display_short) psi-mi:hxt2_yeast(display_long)|uniprotkb:YM8270.15(orf name)|uniprotkb:YMR011W(locus name)|uniprotkb:HXT2(gene name)|psi-mi:HXT2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321320|imex:IM-26944-403 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013724.1|sgd:S000004613|dip:DIP-7912N|mint:P23585|ensemblfungi:YMR011W(gene)|ensemblfungi:YMR011W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|ensemblgenomes:YMR011W(identity) refseq:NP_013724.1|sgd:S000004613|dip:DIP-7912N|mint:P23585|ensemblfungi:YMR011W(gene)|ensemblfungi:YMR011W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0015146"(pentose transmembrane transporter activity)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|ensemblgenomes:YMR011W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:d4PFyh6BHnB/WnnF3A4GF3EphgY559292 rogid:d4PFyh6BHnB/WnnF3A4GF3EphgY559292 rigid:FRgWjE4Ag9ELdiZ7ZOG7Yp1GtWg false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46951 uniprotkb:P46951 intact:EBI-23455|uniprotkb:D6VUY0|ensemblfungi:YGR198W intact:EBI-23455|uniprotkb:D6VUY0|ensemblfungi:YGR198W psi-mi:ypp1_yeast(display_long)|uniprotkb:YGR198W(locus name)|uniprotkb:G7594(orf name)|uniprotkb:YPP1(gene name)|psi-mi:YPP1(display_short)|uniprotkb:Alpha-synuclein protective protein 1(gene name synonym) psi-mi:ypp1_yeast(display_long)|uniprotkb:YGR198W(locus name)|uniprotkb:G7594(orf name)|uniprotkb:YPP1(gene name)|psi-mi:YPP1(display_short)|uniprotkb:Alpha-synuclein protective protein 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321308|imex:IM-26944-249 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003430|refseq:NP_011714.3|dip:DIP-6350N|mint:P46951|ensemblfungi:YGR198W(gene)|ensemblfungi:YGR198W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0019236"(response to pheromone)|go:"GO:0030479"(actin cortical patch)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:4N5C|go:"GO:0005829"(cytosol)|ensemblgenomes:YGR198W(identity) sgd:S000003430|refseq:NP_011714.3|dip:DIP-6350N|mint:P46951|ensemblfungi:YGR198W(gene)|ensemblfungi:YGR198W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0019236"(response to pheromone)|go:"GO:0030479"(actin cortical patch)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:4N5C|go:"GO:0005829"(cytosol)|ensemblgenomes:YGR198W(identity) - crc64:AC42730C8B9C3E4B crc64:AC42730C8B9C3E4B figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:DN/jdwQiPEurX88Vs2Lj5oXMLzQ559292 rogid:DN/jdwQiPEurX88Vs2Lj5oXMLzQ559292 rigid:NM41qHg86lvzhGtHefOk6kJn1D0 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P14359 uniprotkb:P14359 intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C intact:EBI-26122|uniprotkb:D6VW35|uniprotkb:Q6B236|ensemblfungi:YJL151C psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:sna3_yeast(display_long)|uniprotkb:J0630(orf name)|uniprotkb:YJL151C(locus name)|uniprotkb:SNA3(gene name)|psi-mi:SNA3(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321296|imex:IM-26944-247 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD|ensemblgenomes:YJL151C(identity) refseq:NP_012384.1|sgd:S000003687|mint:P14359|dip:DIP-1730N|ensemblfungi:YJL151C(gene)|ensemblfungi:YJL151C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000328"(fungal-type vacuole lumen)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0044257"(cellular protein catabolic process)|interpro:IPR000612(Protein of unknown function UPF0057)|rcsb pdb:4LCD|ensemblgenomes:YJL151C(identity) - crc64:DBA26AF5B769C02A crc64:DBA26AF5B769C02A figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 rogid:0sViFfDsVtQHk/Stc+aK423Mhmo559292 rigid:skQeSHhz/VkqoysqL6CDrZf8ReQ false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47165 uniprotkb:P47165 intact:EBI-25682|uniprotkb:D6VWV1|ensemblfungi:YJR133W intact:EBI-25682|uniprotkb:D6VWV1|ensemblfungi:YJR133W psi-mi:xpt1_yeast(display_long)|uniprotkb:XPT1(gene name)|psi-mi:XPT1(display_short)|uniprotkb:J2118(orf name)|uniprotkb:YJR133W(locus name) psi-mi:xpt1_yeast(display_long)|uniprotkb:XPT1(gene name)|psi-mi:XPT1(display_short)|uniprotkb:J2118(orf name)|uniprotkb:YJR133W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321284|imex:IM-26944-493 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012667.1|sgd:S000003894|mint:P47165|dip:DIP-1576N|ensemblfungi:YJR133W(gene)|ensemblfungi:YJR133W_mRNA(transcript)|go:"GO:0000310"(xanthine phosphoribosyltransferase activity)|go:"GO:0004422"(hypoxanthine phosphoribosyltransferase activity)|go:"GO:0004615"(phosphomannomutase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0032263"(GMP salvage)|go:"GO:0032264"(IMP salvage)|go:"GO:0032265"(XMP salvage)|go:"GO:0046100"(hypoxanthine metabolic process)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR029057|ensemblgenomes:YJR133W(identity) refseq:NP_012667.1|sgd:S000003894|mint:P47165|dip:DIP-1576N|ensemblfungi:YJR133W(gene)|ensemblfungi:YJR133W_mRNA(transcript)|go:"GO:0000310"(xanthine phosphoribosyltransferase activity)|go:"GO:0004422"(hypoxanthine phosphoribosyltransferase activity)|go:"GO:0004615"(phosphomannomutase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0032263"(GMP salvage)|go:"GO:0032264"(IMP salvage)|go:"GO:0032265"(XMP salvage)|go:"GO:0046100"(hypoxanthine metabolic process)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR029057|ensemblgenomes:YJR133W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:hjdGDsZ62F5m8o7QAcZMoVVXWVc559292 rogid:hjdGDsZ62F5m8o7QAcZMoVVXWVc559292 rigid:jsNT9XS6X3zFbHww84UbKTAHsLA false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P05319 uniprotkb:P05319 intact:EBI-15456|uniprotkb:D6W227|ensemblfungi:YOL039W intact:EBI-15456|uniprotkb:D6W227|ensemblfungi:YOL039W psi-mi:rla2_yeast(display_long)|uniprotkb:RPP2A(gene name)|psi-mi:RPP2A(display_short)|uniprotkb:L12EIB(gene name synonym)|uniprotkb:RPA2(gene name synonym)|uniprotkb:RPL44(gene name synonym)|uniprotkb:RPLA2(gene name synonym)|uniprotkb:L12eIB(gene name synonym)|uniprotkb:YP2alpha(gene name synonym)|uniprotkb:L44(gene name synonym)|uniprotkb:YOL039W(locus name)|uniprotkb:Large ribosomal subunit protein P2-A(gene name synonym) psi-mi:rla2_yeast(display_long)|uniprotkb:RPP2A(gene name)|psi-mi:RPP2A(display_short)|uniprotkb:L12EIB(gene name synonym)|uniprotkb:RPA2(gene name synonym)|uniprotkb:RPL44(gene name synonym)|uniprotkb:RPLA2(gene name synonym)|uniprotkb:L12eIB(gene name synonym)|uniprotkb:YP2alpha(gene name synonym)|uniprotkb:L44(gene name synonym)|uniprotkb:YOL039W(locus name)|uniprotkb:Large ribosomal subunit protein P2-A(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321272|imex:IM-26944-491 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014603.1|sgd:S000005399|ensemblfungi:YOL039W(gene)|ensemblfungi:YOL039W_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002182"(cytoplasmic translational elongation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030295"(protein kinase activator activity)|interpro:IPR027534|interpro:IPR038716|interpro:IPR044076|rcsb pdb:4V6I|dip:DIP-2506N|ensemblgenomes:YOL039W(identity) refseq:NP_014603.1|sgd:S000005399|ensemblfungi:YOL039W(gene)|ensemblfungi:YOL039W_mRNA(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002182"(cytoplasmic translational elongation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030295"(protein kinase activator activity)|interpro:IPR027534|interpro:IPR038716|interpro:IPR044076|rcsb pdb:4V6I|dip:DIP-2506N|ensemblgenomes:YOL039W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:bvmZbhGsNuMJEdAv9ac1wD6Y+Rs559292 rogid:bvmZbhGsNuMJEdAv9ac1wD6Y+Rs559292 rigid:1FbcKVjG1bkiyTwlXfKM1OHlVNc false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04396 uniprotkb:Q04396 intact:EBI-35436|uniprotkb:D6VTC5|ensemblfungi:YDR503C intact:EBI-35436|uniprotkb:D6VTC5|ensemblfungi:YDR503C psi-mi:lpp1_yeast(display_long)|uniprotkb:LPP1(gene name)|psi-mi:LPP1(display_short)|uniprotkb:YDR503C(locus name)|uniprotkb:D9719.9(orf name)|uniprotkb:Phosphatidate phosphatase(gene name synonym)|uniprotkb:Lysophosphatidate phosphatase(gene name synonym) psi-mi:lpp1_yeast(display_long)|uniprotkb:LPP1(gene name)|psi-mi:LPP1(display_short)|uniprotkb:YDR503C(locus name)|uniprotkb:D9719.9(orf name)|uniprotkb:Phosphatidate phosphatase(gene name synonym)|uniprotkb:Lysophosphatidate phosphatase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321260|imex:IM-26944-581 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010791.3|sgd:S000002911|mint:Q04396|dip:DIP-1415N|ensemblfungi:YDR503C(gene)|ensemblfungi:YDR503C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000810"(diacylglycerol diphosphate phosphatase activity)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042577"(lipid phosphatase activity)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR036938|interpro:IPR043216|reactome:R-SCE-1660661|reactome:R-SCE-2029485|reactome:R-SCE-419408|ensemblgenomes:YDR503C(identity) refseq:NP_010791.3|sgd:S000002911|mint:Q04396|dip:DIP-1415N|ensemblfungi:YDR503C(gene)|ensemblfungi:YDR503C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000810"(diacylglycerol diphosphate phosphatase activity)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0008195"(phosphatidate phosphatase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042577"(lipid phosphatase activity)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR036938|interpro:IPR043216|reactome:R-SCE-1660661|reactome:R-SCE-2029485|reactome:R-SCE-419408|ensemblgenomes:YDR503C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:WSLmGL9DQuSCqyVf3vQjK753VsI559292 rogid:WSLmGL9DQuSCqyVf3vQjK753VsI559292 rigid:E2aP0hjOJpEZPGuicS+YcRDMKOo false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38787 uniprotkb:P38787 intact:EBI-12913|uniprotkb:D3DL12|ensemblfungi:YHR063C intact:EBI-12913|uniprotkb:D3DL12|ensemblfungi:YHR063C psi-mi:pane_yeast(display_long)|uniprotkb:YHR063C(locus name)|uniprotkb:PAN5(gene name)|psi-mi:PAN5(display_short)|uniprotkb:Ketopantoate reductase(gene name synonym) psi-mi:pane_yeast(display_long)|uniprotkb:YHR063C(locus name)|uniprotkb:PAN5(gene name)|psi-mi:PAN5(display_short)|uniprotkb:Ketopantoate reductase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321248|imex:IM-26944-579 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011930.1|sgd:S000001105|ensemblfungi:YHR063C(gene)|ensemblfungi:YHR063C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008677"(2-dehydropantoate 2-reductase activity)|go:"GO:0015940"(pantothenate biosynthetic process)|go:"GO:0050661"(NADP binding)|interpro:IPR003710(Ketopantoate reductase ApbA/PanE)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR013332(Ketopantoate reductase ApbA/PanE, N-terminal)|interpro:IPR013752(Ketopantoate reductase ApbA/PanE, C-terminal)|interpro:IPR036291|mint:P38787|dip:DIP-5591N|ensemblgenomes:YHR063C(identity) refseq:NP_011930.1|sgd:S000001105|ensemblfungi:YHR063C(gene)|ensemblfungi:YHR063C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008677"(2-dehydropantoate 2-reductase activity)|go:"GO:0015940"(pantothenate biosynthetic process)|go:"GO:0050661"(NADP binding)|interpro:IPR003710(Ketopantoate reductase ApbA/PanE)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR013332(Ketopantoate reductase ApbA/PanE, N-terminal)|interpro:IPR013752(Ketopantoate reductase ApbA/PanE, C-terminal)|interpro:IPR036291|mint:P38787|dip:DIP-5591N|ensemblgenomes:YHR063C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:Ppp+rFeMgh+E/8WIRLrqgxYKn2Y559292 rogid:Ppp+rFeMgh+E/8WIRLrqgxYKn2Y559292 rigid:SqqfUO8H+lYyFHdkHyPz2JBBWt8 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38426 uniprotkb:P38426 intact:EBI-19448|uniprotkb:D6W087|uniprotkb:Q6B1W2|ensemblfungi:YMR261C intact:EBI-19448|uniprotkb:D6W087|uniprotkb:Q6B1W2|ensemblfungi:YMR261C psi-mi:tps3_yeast(display_long)|uniprotkb:TPS3(gene name)|psi-mi:TPS3(display_short)|uniprotkb:YMR261C(locus name)|uniprotkb:YM8156.03C(orf name)|uniprotkb:Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 115 kDa subunit(gene name synonym) psi-mi:tps3_yeast(display_long)|uniprotkb:TPS3(gene name)|psi-mi:TPS3(display_short)|uniprotkb:YMR261C(locus name)|uniprotkb:YM8156.03C(orf name)|uniprotkb:Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 115 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321236|imex:IM-26944-55 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013988.1|sgd:S000004874|ensemblfungi:YMR261C(gene)|ensemblfungi:YMR261C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005946"("alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)")|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0016311"(dephosphorylation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR001830(Glycosyl transferase, family 20)|interpro:IPR003337(Trehalose-phosphatase)|interpro:IPR036412|dip:DIP-891N|mint:P38426|ensemblgenomes:YMR261C(identity) refseq:NP_013988.1|sgd:S000004874|ensemblfungi:YMR261C(gene)|ensemblfungi:YMR261C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005946"("alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)")|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0016311"(dephosphorylation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR001830(Glycosyl transferase, family 20)|interpro:IPR003337(Trehalose-phosphatase)|interpro:IPR036412|dip:DIP-891N|mint:P38426|ensemblgenomes:YMR261C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:aY+Gu2+xxYxfe40pjJ1KTaYbDxM559292 rogid:aY+Gu2+xxYxfe40pjJ1KTaYbDxM559292 rigid:mR7E0oiSYRyAGF2jNVHG6xTn8y8 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P49775 uniprotkb:P49775 intact:EBI-8423|uniprotkb:Q6TQU2|uniprotkb:Q6TQU3|uniprotkb:D6VST4 intact:EBI-8423|uniprotkb:Q6TQU2|uniprotkb:Q6TQU3|uniprotkb:D6VST4 psi-mi:hnt2_yeast(display_long)|uniprotkb:HNT2(gene name)|psi-mi:HNT2(display_short)|uniprotkb:YDR305C(locus name)|uniprotkb:D9740.15(orf name)|uniprotkb:APH1(gene name synonym)|uniprotkb:Diadenosine 5',5'''-P1,P3-triphosphate hydrolase(gene name synonym)|uniprotkb:Dinucleosidetriphosphatase(gene name synonym)|uniprotkb:AP3A hydrolase(gene name synonym)|uniprotkb:Hit family protein 2(gene name synonym) psi-mi:hnt2_yeast(display_long)|uniprotkb:HNT2(gene name)|psi-mi:HNT2(display_short)|uniprotkb:YDR305C(locus name)|uniprotkb:D9740.15(orf name)|uniprotkb:APH1(gene name synonym)|uniprotkb:Diadenosine 5',5'''-P1,P3-triphosphate hydrolase(gene name synonym)|uniprotkb:Dinucleosidetriphosphatase(gene name synonym)|uniprotkb:AP3A hydrolase(gene name synonym)|uniprotkb:Hit family protein 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321224|imex:IM-26944-683 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002713|refseq:NP_010591.1|dip:DIP-4620N|mint:P49775|go:"GO:0000166"(nucleotide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0009164"(nucleoside catabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0047710"("bis(5'-adenosyl)-triphosphatase activity")|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR001310("Histidine triad (HIT) protein")|interpro:IPR011146(Histidine triad-like motif)|interpro:IPR019808|interpro:IPR036265|interpro:IPR039383|ensemblgenomes:YDR305C(identity) sgd:S000002713|refseq:NP_010591.1|dip:DIP-4620N|mint:P49775|go:"GO:0000166"(nucleotide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0009164"(nucleoside catabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0047710"("bis(5'-adenosyl)-triphosphatase activity")|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR001310("Histidine triad (HIT) protein")|interpro:IPR011146(Histidine triad-like motif)|interpro:IPR019808|interpro:IPR036265|interpro:IPR039383|ensemblgenomes:YDR305C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:KK/aqRgXTNNl7bNLOQU4H+ZYPOo559292 rogid:KK/aqRgXTNNl7bNLOQU4H+ZYPOo559292 rigid:TR7ChOecaT7CdIG6Z8+MV4YEvyc false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04053 uniprotkb:Q04053 intact:EBI-30464|uniprotkb:D6VT55|ensemblfungi:YDR425W intact:EBI-30464|uniprotkb:D6VT55|ensemblfungi:YDR425W psi-mi:snx41_yeast(display_long)|uniprotkb:SNX41(gene name)|psi-mi:SNX41(display_short)|uniprotkb:YDR425W(locus name) psi-mi:snx41_yeast(display_long)|uniprotkb:SNX41(gene name)|psi-mi:SNX41(display_short)|uniprotkb:YDR425W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321212|imex:IM-26944-681 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010713.1|sgd:S000002833|dip:DIP-3920N|mint:Q04053|ensemblfungi:YDR425W(gene)|ensemblfungi:YDR425W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR001683(Phox-like)|interpro:IPR036871|interpro:IPR044106|ensemblgenomes:YDR425W(identity) refseq:NP_010713.1|sgd:S000002833|dip:DIP-3920N|mint:Q04053|ensemblfungi:YDR425W(gene)|ensemblfungi:YDR425W_mRNA(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR001683(Phox-like)|interpro:IPR036871|interpro:IPR044106|ensemblgenomes:YDR425W(identity) - crc64:B9A064EDE0C52085 crc64:B9A064EDE0C52085 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:a11BZwDQ+mpXWGPJFpenA1NItFQ559292 rogid:a11BZwDQ+mpXWGPJFpenA1NItFQ559292 rigid:ZC+ulZiLxz+4gq2tXAnLTAt0ovw false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04894 uniprotkb:Q04894 intact:EBI-27680|uniprotkb:D6W0E6|ensemblfungi:YMR318C intact:EBI-27680|uniprotkb:D6W0E6|ensemblfungi:YMR318C psi-mi:adh6_yeast(display_long)|uniprotkb:ADH6(gene name)|psi-mi:ADH6(display_short)|uniprotkb:YMR318C(locus name)|uniprotkb:YM9924.10C(orf name)|uniprotkb:NADP-dependent alcohol dehydrogenase VI(gene name synonym)|uniprotkb:ScADHVI(gene name synonym) psi-mi:adh6_yeast(display_long)|uniprotkb:ADH6(gene name)|psi-mi:ADH6(display_short)|uniprotkb:YMR318C(locus name)|uniprotkb:YM9924.10C(orf name)|uniprotkb:NADP-dependent alcohol dehydrogenase VI(gene name synonym)|uniprotkb:ScADHVI(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321200|imex:IM-26944-245 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004937|refseq:NP_014051.3|dip:DIP-6308N|ensemblfungi:YMR318C(gene)|ensemblfungi:YMR318C_mRNA(transcript)|go:"GO:0006066"(alcohol metabolic process)|go:"GO:0006081"(cellular aldehyde metabolic process)|go:"GO:0008106"("alcohol dehydrogenase (NADP+) activity")|go:"GO:0008270"(zinc ion binding)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0033833"("hydroxymethylfurfural reductase (NADH) activity")|go:"GO:0033845"("hydroxymethylfurfural reductase (NADPH) activity")|go:"GO:0033859"(furaldehyde metabolic process)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR036291|rcsb pdb:1PIW|rcsb pdb:1PS0|rcsb pdb:1Q1N|ensemblgenomes:YMR318C(identity) sgd:S000004937|refseq:NP_014051.3|dip:DIP-6308N|ensemblfungi:YMR318C(gene)|ensemblfungi:YMR318C_mRNA(transcript)|go:"GO:0006066"(alcohol metabolic process)|go:"GO:0006081"(cellular aldehyde metabolic process)|go:"GO:0008106"("alcohol dehydrogenase (NADP+) activity")|go:"GO:0008270"(zinc ion binding)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0033833"("hydroxymethylfurfural reductase (NADH) activity")|go:"GO:0033845"("hydroxymethylfurfural reductase (NADPH) activity")|go:"GO:0033859"(furaldehyde metabolic process)|interpro:IPR002328(Alcohol dehydrogenase, zinc-containing, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR036291|rcsb pdb:1PIW|rcsb pdb:1PS0|rcsb pdb:1Q1N|ensemblgenomes:YMR318C(identity) - crc64:3F785BE0C5ED8CF1 crc64:3F785BE0C5ED8CF1 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:kzlFYzXPLaaojbVGYkA5qWN/ZPA559292 rogid:kzlFYzXPLaaojbVGYkA5qWN/ZPA559292 rigid:gIvrsiUCJv0+W0nXDtJll+n5uw8 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12335 uniprotkb:Q12335 intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 intact:EBI-14064|ensemblfungi:YDR032C|uniprotkb:D6VS16 psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:pst2_yeast(display_long)|uniprotkb:PST2(gene name)|psi-mi:PST2(display_short)|uniprotkb:D3422(orf name)|uniprotkb:YD9673.02C(orf name)|uniprotkb:YDR032C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321188|imex:IM-26944-577 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N|ensemblgenomes:YDR032C(identity) refseq:NP_010315.1|sgd:S000002439|ensemblfungi:YDR032C(gene)|ensemblfungi:YDR032C_mRNA(transcript)|go:"GO:0003955"("NAD(P)H dehydrogenase (quinone) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0010181"(FMN binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR005025(NADPH-dependent FMN reductase)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR010089(Flavoprotein WrbA)|interpro:IPR029039|rcsb pdb:5MP4|mint:Q12335|dip:DIP-1762N|ensemblgenomes:YDR032C(identity) - crc64:1056E7A1F3E82288 crc64:1056E7A1F3E82288 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 rogid:t6Gwn82sZzxGdkpuLGWVXsu2aXU559292 rigid:FBdVCWSad9XI4lsMaXGnQ2NnSAg false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01560 uniprotkb:Q01560 intact:EBI-12114|uniprotkb:D6VT60|ensemblfungi:YDR432W intact:EBI-12114|uniprotkb:D6VT60|ensemblfungi:YDR432W psi-mi:nop3_yeast(display_long)|uniprotkb:MTR13(gene name synonym)|uniprotkb:MTS1(gene name synonym)|uniprotkb:Mitochondrial targeting suppressor 1 protein(gene name synonym)|uniprotkb:Nuclear polyadenylated RNA-binding protein 1(gene name synonym)|uniprotkb:NPL3(gene name)|psi-mi:NPL3(display_short)|uniprotkb:NAB1(gene name synonym)|uniprotkb:YDR432W(locus name)|uniprotkb:D9461.19(orf name)|uniprotkb:NOP3(gene name synonym) psi-mi:nop3_yeast(display_long)|uniprotkb:MTR13(gene name synonym)|uniprotkb:MTS1(gene name synonym)|uniprotkb:Mitochondrial targeting suppressor 1 protein(gene name synonym)|uniprotkb:Nuclear polyadenylated RNA-binding protein 1(gene name synonym)|uniprotkb:NPL3(gene name)|psi-mi:NPL3(display_short)|uniprotkb:NAB1(gene name synonym)|uniprotkb:YDR432W(locus name)|uniprotkb:D9461.19(orf name)|uniprotkb:NOP3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321176|imex:IM-26944-575 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDR432W(gene)|ensemblfungi:YDR432W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006415"(translational termination)|go:"GO:0008143"("poly(A) binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:2000805"("negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034166|interpro:IPR035979|rcsb pdb:2JD5|rcsb pdb:2JVO|rcsb pdb:2JVR|rcsb pdb:2OSQ|rcsb pdb:2OSR|refseq:NP_010720.3|sgd:S000002840|dip:DIP-6464N|ensemblgenomes:YDR432W(identity) ensemblfungi:YDR432W(gene)|ensemblfungi:YDR432W_mRNA(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006415"(translational termination)|go:"GO:0008143"("poly(A) binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:2000805"("negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034166|interpro:IPR035979|rcsb pdb:2JD5|rcsb pdb:2JVO|rcsb pdb:2JVR|rcsb pdb:2OSQ|rcsb pdb:2OSR|refseq:NP_010720.3|sgd:S000002840|dip:DIP-6464N|ensemblgenomes:YDR432W(identity) - crc64:024439E4B6578787 crc64:024439E4B6578787 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:R/g8r9x82rdG8AThC5VQcbgY6u4559292 rogid:R/g8r9x82rdG8AThC5VQcbgY6u4559292 rigid:aUrxd38RmaOVGpfLZs3OWyAms9s false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43616 uniprotkb:P43616 intact:EBI-5137|uniprotkb:D6VTS7|ensemblfungi:YFR044C intact:EBI-5137|uniprotkb:D6VTS7|ensemblfungi:YFR044C psi-mi:dug1_yeast(display_long)|uniprotkb:DUG1(gene name)|psi-mi:DUG1(display_short)|uniprotkb:GSH degradosomal complex subunit DUG1(gene name synonym)|uniprotkb:Deficient in utilization of glutathione protein 1(gene name synonym)|uniprotkb:YFR044C(locus name) psi-mi:dug1_yeast(display_long)|uniprotkb:DUG1(gene name)|psi-mi:DUG1(display_short)|uniprotkb:GSH degradosomal complex subunit DUG1(gene name synonym)|uniprotkb:Deficient in utilization of glutathione protein 1(gene name synonym)|uniprotkb:YFR044C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321164|imex:IM-26944-155 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116702.1|sgd:S000001940|dip:DIP-6492N|mint:P43616|ensemblfungi:YFR044C(gene)|ensemblfungi:YFR044C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006508"(proteolysis)|go:"GO:0006751"(glutathione catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0008242"(omega peptidase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070573"(metallodipeptidase activity)|interpro:IPR002933(Peptidase M20)|interpro:IPR011650(Peptidase M20, dimerisation)|interpro:IPR017153(Glutathione degradosome, DUG1)|rcsb pdb:4G1P|reactome:R-SCE-174403|ensemblgenomes:YFR044C(identity) refseq:NP_116702.1|sgd:S000001940|dip:DIP-6492N|mint:P43616|ensemblfungi:YFR044C(gene)|ensemblfungi:YFR044C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006508"(proteolysis)|go:"GO:0006751"(glutathione catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0008242"(omega peptidase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070573"(metallodipeptidase activity)|interpro:IPR002933(Peptidase M20)|interpro:IPR011650(Peptidase M20, dimerisation)|interpro:IPR017153(Glutathione degradosome, DUG1)|rcsb pdb:4G1P|reactome:R-SCE-174403|ensemblgenomes:YFR044C(identity) - crc64:3E53773A945F5EBC crc64:3E53773A945F5EBC figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:PWGPSfN2a8aF5FVaFe5CUuMDCnM559292 rogid:PWGPSfN2a8aF5FVaFe5CUuMDCnM559292 rigid:JotxMTRoxBauW+SQy423R8ozsyM false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25087 uniprotkb:P25087 intact:EBI-6567|uniprotkb:D6VZG6|ensemblfungi:YML008C intact:EBI-6567|uniprotkb:D6VZG6|ensemblfungi:YML008C psi-mi:erg6_yeast(display_long)|uniprotkb:ERG6(gene name)|psi-mi:ERG6(display_short)|uniprotkb:ISE1(gene name synonym)|uniprotkb:LIS1(gene name synonym)|uniprotkb:SED6(gene name synonym)|uniprotkb:YML008C(locus name)|uniprotkb:YM9571.10C(orf name)|uniprotkb:"Delta(24)-sterol C-methyltransferase"(gene name synonym) psi-mi:erg6_yeast(display_long)|uniprotkb:ERG6(gene name)|psi-mi:ERG6(display_short)|uniprotkb:ISE1(gene name synonym)|uniprotkb:LIS1(gene name synonym)|uniprotkb:SED6(gene name synonym)|uniprotkb:YML008C(locus name)|uniprotkb:YM9571.10C(orf name)|uniprotkb:"Delta(24)-sterol C-methyltransferase"(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321152|imex:IM-26944-489 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013706.1|sgd:S000004467|mint:P25087|dip:DIP-3816N|ensemblfungi:YML008C(gene)|ensemblfungi:YML008C_mRNA(transcript)|go:"GO:0003838"(sterol 24-C-methyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0032259"(methylation)|go:"GO:0042802"(identical protein binding)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR013705(Sterol methyltransferase C-terminal)|interpro:IPR029063|interpro:IPR030384|ensemblgenomes:YML008C(identity) refseq:NP_013706.1|sgd:S000004467|mint:P25087|dip:DIP-3816N|ensemblfungi:YML008C(gene)|ensemblfungi:YML008C_mRNA(transcript)|go:"GO:0003838"(sterol 24-C-methyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0032259"(methylation)|go:"GO:0042802"(identical protein binding)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR013705(Sterol methyltransferase C-terminal)|interpro:IPR029063|interpro:IPR030384|ensemblgenomes:YML008C(identity) - crc64:C3A2B6DF2C14ED63 crc64:C3A2B6DF2C14ED63 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid://B8LWgQFmbcX+wA6okkQ1DDrxY559292 rogid://B8LWgQFmbcX+wA6okkQ1DDrxY559292 rigid:YhUpUJdkaEfRvVIXLeqEGVW2sLM false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40088 uniprotkb:P40088 intact:EBI-7138|uniprotkb:D3DM52|ensemblfungi:YER145C intact:EBI-7138|uniprotkb:D3DM52|ensemblfungi:YER145C psi-mi:ftr1_yeast(display_long)|uniprotkb:FTR1(gene name)|psi-mi:FTR1(display_short)|uniprotkb:YER145C(locus name) psi-mi:ftr1_yeast(display_long)|uniprotkb:FTR1(gene name)|psi-mi:FTR1(display_short)|uniprotkb:YER145C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321140|imex:IM-26944-53 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-5376N|refseq:NP_011072.1|sgd:S000000947|mint:P40088|ensemblfungi:YER145C(gene)|ensemblfungi:YER145C_mRNA(transcript)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:1901684"(arsenate ion transmembrane transport)|interpro:IPR004923(Iron permease FTR1)|interpro:IPR005217(Conserved hypothetical protein CHP00145)|ensemblgenomes:YER145C(identity) dip:DIP-5376N|refseq:NP_011072.1|sgd:S000000947|mint:P40088|ensemblfungi:YER145C(gene)|ensemblfungi:YER145C_mRNA(transcript)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0015093"(ferrous iron transmembrane transporter activity)|go:"GO:0033573"(high-affinity iron permease complex)|go:"GO:0034755"(iron ion transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:1901684"(arsenate ion transmembrane transport)|interpro:IPR004923(Iron permease FTR1)|interpro:IPR005217(Conserved hypothetical protein CHP00145)|ensemblgenomes:YER145C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:fhDKp2YYbK7C+ACjHx1AuPCyts4559292 rogid:fhDKp2YYbK7C+ACjHx1AuPCyts4559292 rigid:FUypwuknJETGaHcxlX44UAZN16Y false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06169 uniprotkb:Q06169 intact:EBI-31008|intact:EBI-937900|uniprotkb:Q66R43|uniprotkb:D6VYW6|ensemblfungi:YLR324W intact:EBI-31008|intact:EBI-937900|uniprotkb:Q66R43|uniprotkb:D6VYW6|ensemblfungi:YLR324W psi-mi:pex30_yeast(display_long)|uniprotkb:PEX30(gene name)|psi-mi:PEX30(display_short)|uniprotkb:Peroxin-30(gene name synonym)|uniprotkb:YLR324W(locus name) psi-mi:pex30_yeast(display_long)|uniprotkb:PEX30(gene name)|psi-mi:PEX30(display_short)|uniprotkb:Peroxin-30(gene name synonym)|uniprotkb:YLR324W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321128|imex:IM-26944-333 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013428.1|sgd:S000004316|dip:DIP-1800N|mint:Q06169|ensemblfungi:YLR324W(gene)|ensemblfungi:YLR324W_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005933"(cellular bud)|go:"GO:0007031"(peroxisome organization)|go:"GO:0032581"(ER-dependent peroxisome organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071944"(cell periphery)|go:"GO:0097749"(membrane tubulation)|go:"GO:1900063"(regulation of peroxisome organization)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR010482(Integral peroxisomal membrane peroxin)|ensemblgenomes:YLR324W(identity) refseq:NP_013428.1|sgd:S000004316|dip:DIP-1800N|mint:Q06169|ensemblfungi:YLR324W(gene)|ensemblfungi:YLR324W_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005933"(cellular bud)|go:"GO:0007031"(peroxisome organization)|go:"GO:0032581"(ER-dependent peroxisome organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071944"(cell periphery)|go:"GO:0097749"(membrane tubulation)|go:"GO:1900063"(regulation of peroxisome organization)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR010482(Integral peroxisomal membrane peroxin)|ensemblgenomes:YLR324W(identity) - crc64:417DBE56B1C8B1D5 crc64:417DBE56B1C8B1D5 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:vkvJ4GqSW60wMG0m3ChlSzwcC3c559292 rogid:vkvJ4GqSW60wMG0m3ChlSzwcC3c559292 rigid:tYceXTS4/Br+Xaa+Ktmtn4Wt2+8 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25376 uniprotkb:P25376 intact:EBI-2357|uniprotkb:D6VQZ1|ensemblfungi:YCL025C intact:EBI-2357|uniprotkb:D6VQZ1|ensemblfungi:YCL025C psi-mi:agp1_yeast(display_long)|uniprotkb:AGP1(gene name)|psi-mi:AGP1(display_short)|uniprotkb:YCL025C(locus name)|uniprotkb:YCL25C(orf name)|uniprotkb:Asparagine/glutamine permease(gene name synonym) psi-mi:agp1_yeast(display_long)|uniprotkb:AGP1(gene name)|psi-mi:AGP1(display_short)|uniprotkb:YCL025C(locus name)|uniprotkb:YCL25C(orf name)|uniprotkb:Asparagine/glutamine permease(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321116|imex:IM-26944-51 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009905.3|sgd:S000000530|dip:DIP-4973N|mint:P25376|ensemblfungi:YCL025C(gene)|ensemblfungi:YCL025C_mRNA(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015192"(L-phenylalanine transmembrane transporter activity)|go:"GO:0015193"(L-proline transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0098718"(serine import across plasma membrane)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region)|ensemblgenomes:YCL025C(identity) refseq:NP_009905.3|sgd:S000000530|dip:DIP-4973N|mint:P25376|ensemblfungi:YCL025C(gene)|ensemblfungi:YCL025C_mRNA(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015192"(L-phenylalanine transmembrane transporter activity)|go:"GO:0015193"(L-proline transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0098718"(serine import across plasma membrane)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region)|ensemblgenomes:YCL025C(identity) - crc64:8E19A836C2F6C50F crc64:8E19A836C2F6C50F figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:bB5pBnaoMUTwxlz8v5MAjCWc4Mg559292 rogid:bB5pBnaoMUTwxlz8v5MAjCWc4Mg559292 rigid:zXJbzaNdl/jIxnldAJEZRVDfqVY false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40494 uniprotkb:P40494 intact:EBI-9703|uniprotkb:Q02553|ensemblfungi:YIL095W|uniprotkb:D6VVJ2 intact:EBI-9703|uniprotkb:Q02553|ensemblfungi:YIL095W|uniprotkb:D6VVJ2 psi-mi:prk1_yeast(display_long)|uniprotkb:PAK1(gene name synonym)|uniprotkb:YIL095W(locus name)|uniprotkb:PRK1(gene name)|psi-mi:PRK1(display_short)|uniprotkb:p53-regulating kinase 1(gene name synonym) psi-mi:prk1_yeast(display_long)|uniprotkb:PAK1(gene name synonym)|uniprotkb:YIL095W(locus name)|uniprotkb:PRK1(gene name)|psi-mi:PRK1(display_short)|uniprotkb:p53-regulating kinase 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321104|imex:IM-26944-401 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|reactome:R-SCE-8856828|go:"GO:0106311"|go:"GO:0120133"(negative regulation of actin cortical patch assembly)|go:"GO:1900186"(negative regulation of clathrin-dependent endocytosis)|ensemblfungi:YIL095W(gene)|ensemblfungi:YIL095W_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|refseq:NP_012171.1|sgd:S000001357|mint:P40494|dip:DIP-6271N|ensemblgenomes:YIL095W(identity) interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|reactome:R-SCE-8856828|go:"GO:0106311"|go:"GO:0120133"(negative regulation of actin cortical patch assembly)|go:"GO:1900186"(negative regulation of clathrin-dependent endocytosis)|ensemblfungi:YIL095W(gene)|ensemblfungi:YIL095W_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007015"(actin filament organization)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030479"(actin cortical patch)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0043332"(mating projection tip)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|refseq:NP_012171.1|sgd:S000001357|mint:P40494|dip:DIP-6271N|ensemblgenomes:YIL095W(identity) - crc64:AF710F930B39BC7E crc64:AF710F930B39BC7E figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:Etg7IBo3vx49huiVMgmNjDDSoVo559292 rogid:Etg7IBo3vx49huiVMgmNjDDSoVo559292 rigid:q7XXUDD/jQ394jwVZsP5QPxrfMI false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P22202 uniprotkb:P22202 intact:EBI-8621|uniprotkb:D3DM10|ensemblfungi:YER103W intact:EBI-8621|uniprotkb:D3DM10|ensemblfungi:YER103W psi-mi:hsp74_yeast(display_long)|uniprotkb:YER103W(locus name)|uniprotkb:SSA4(gene name)|psi-mi:SSA4(display_short) psi-mi:hsp74_yeast(display_long)|uniprotkb:YER103W(locus name)|uniprotkb:SSA4(gene name)|psi-mi:SSA4(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321567|imex:IM-26944-687 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000905|refseq:NP_011029.3|mint:P22202|dip:DIP-3916N|ensemblfungi:YER103W(gene)|ensemblfungi:YER103W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:3UPV|ensemblgenomes:YER103W(identity) sgd:S000000905|refseq:NP_011029.3|mint:P22202|dip:DIP-3916N|ensemblfungi:YER103W(gene)|ensemblfungi:YER103W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:3UPV|ensemblgenomes:YER103W(identity) - crc64:7A976357AC35C352 crc64:7A976357AC35C352 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:QiL3U6hhfGX8ulZBYuNAL68zI2s559292 rogid:QiL3U6hhfGX8ulZBYuNAL68zI2s559292 rigid:O5xdhwk1RdvM3wn42EYerQyLsiQ false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23254 uniprotkb:P23254 intact:EBI-19291|uniprotkb:D6W478|ensemblfungi:YPR074C intact:EBI-19291|uniprotkb:D6W478|ensemblfungi:YPR074C psi-mi:tkt1_yeast(display_long)|uniprotkb:YP9499.29C(orf name)|uniprotkb:YPR074C(locus name)|uniprotkb:TKL1(gene name)|psi-mi:TKL1(display_short) psi-mi:tkt1_yeast(display_long)|uniprotkb:YP9499.29C(orf name)|uniprotkb:YPR074C(locus name)|uniprotkb:TKL1(gene name)|psi-mi:TKL1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321579|imex:IM-26944-165 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015399.1|sgd:S000006278|interpro:IPR029061|interpro:IPR033247|interpro:IPR033248|rcsb pdb:1AY0|rcsb pdb:1GPU|rcsb pdb:1NGS|rcsb pdb:1TKA|rcsb pdb:1TKB|rcsb pdb:1TKC|rcsb pdb:1TRK|interpro:IPR020826|ensemblfungi:YPR074C(gene)|ensemblfungi:YPR074C_mRNA(transcript)|go:"GO:0004802"(transketolase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0046872"(metal ion binding)|interpro:IPR005474(Transketolase, N-terminal)|interpro:IPR005475(Transketolase, central region)|interpro:IPR005478(Bacterial transketolase)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|dip:DIP-6765N|mint:P23254|ensemblgenomes:YPR074C(identity) refseq:NP_015399.1|sgd:S000006278|interpro:IPR029061|interpro:IPR033247|interpro:IPR033248|rcsb pdb:1AY0|rcsb pdb:1GPU|rcsb pdb:1NGS|rcsb pdb:1TKA|rcsb pdb:1TKB|rcsb pdb:1TKC|rcsb pdb:1TRK|interpro:IPR020826|ensemblfungi:YPR074C(gene)|ensemblfungi:YPR074C_mRNA(transcript)|go:"GO:0004802"(transketolase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0046872"(metal ion binding)|interpro:IPR005474(Transketolase, N-terminal)|interpro:IPR005475(Transketolase, central region)|interpro:IPR005478(Bacterial transketolase)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|dip:DIP-6765N|mint:P23254|ensemblgenomes:YPR074C(identity) - crc64:40225EAA23A63835 crc64:40225EAA23A63835 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:rRfdYF2q76Mp6FJzwkOGeefxbOQ559292 rogid:rRfdYF2q76Mp6FJzwkOGeefxbOQ559292 rigid:o61TFPyzIYd/afI27/YDh4Nw72I false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12450 uniprotkb:Q12450 intact:EBI-6598|uniprotkb:D6W282|ensemblfungi:YOR016C intact:EBI-6598|uniprotkb:D6W282|ensemblfungi:YOR016C psi-mi:erp4_yeast(display_long)|uniprotkb:ERP4(gene name)|psi-mi:ERP4(display_short)|uniprotkb:YOR016C(locus name) psi-mi:erp4_yeast(display_long)|uniprotkb:ERP4(gene name)|psi-mi:ERP4(display_short)|uniprotkb:YOR016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321543|imex:IM-26944-407 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014659.1|sgd:S000005542|mint:Q12450|dip:DIP-7868N|ensemblfungi:YOR016C(gene)|ensemblfungi:YOR016C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|reactome:R-SCE-6811434|ensemblgenomes:YOR016C(identity) refseq:NP_014659.1|sgd:S000005542|mint:Q12450|dip:DIP-7868N|ensemblfungi:YOR016C(gene)|ensemblfungi:YOR016C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006621"(protein retention in ER lumen)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|interpro:IPR036598|reactome:R-SCE-6811434|ensemblgenomes:YOR016C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:An7as6LjEDUYrLvEbua3xSL6bEk559292 rogid:An7as6LjEDUYrLvEbua3xSL6bEk559292 rigid:ivGmq69CYVzCdcO/6P8yNLT0ivM false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08645 uniprotkb:Q08645 intact:EBI-7058|uniprotkb:D6W2U3|ensemblfungi:YOR241W intact:EBI-7058|uniprotkb:D6W2U3|ensemblfungi:YOR241W psi-mi:fole_yeast(display_long)|uniprotkb:MET7(gene name)|psi-mi:MET7(display_short)|uniprotkb:MET23(gene name synonym)|uniprotkb:YOR241W(locus name)|uniprotkb:O5248(orf name)|uniprotkb:Folylpoly-gamma-glutamate synthetase(gene name synonym)|uniprotkb:Tetrahydrofolylpolyglutamate synthase(gene name synonym) psi-mi:fole_yeast(display_long)|uniprotkb:MET7(gene name)|psi-mi:MET7(display_short)|uniprotkb:MET23(gene name synonym)|uniprotkb:YOR241W(locus name)|uniprotkb:O5248(orf name)|uniprotkb:Folylpoly-gamma-glutamate synthetase(gene name synonym)|uniprotkb:Tetrahydrofolylpolyglutamate synthase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321531|imex:IM-26944-267 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-4986N|refseq:NP_014884.1|sgd:S000005767|reactome:R-SCE-196757|ensemblfungi:YOR241W(gene)|ensemblfungi:YOR241W_mRNA(transcript)|go:"GO:0004326"(tetrahydrofolylpolyglutamate synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0009396"(folic acid-containing compound biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0046901"(tetrahydrofolylpolyglutamate biosynthetic process)|interpro:IPR001645(Folylpolyglutamate synthetase)|interpro:IPR018109|interpro:IPR023600|interpro:IPR036565|interpro:IPR036615|ensemblgenomes:YOR241W(identity) dip:DIP-4986N|refseq:NP_014884.1|sgd:S000005767|reactome:R-SCE-196757|ensemblfungi:YOR241W(gene)|ensemblfungi:YOR241W_mRNA(transcript)|go:"GO:0004326"(tetrahydrofolylpolyglutamate synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0009396"(folic acid-containing compound biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0046901"(tetrahydrofolylpolyglutamate biosynthetic process)|interpro:IPR001645(Folylpolyglutamate synthetase)|interpro:IPR018109|interpro:IPR023600|interpro:IPR036565|interpro:IPR036615|ensemblgenomes:YOR241W(identity) - crc64:F36811FB4B7E9305 crc64:F36811FB4B7E9305 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:zKgus0A1sVcpz+sp0L0NNqGfY1E559292 rogid:zKgus0A1sVcpz+sp0L0NNqGfY1E559292 rigid:PmGe/UTpTw2B/owR3riiz5r7plg false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11746 uniprotkb:P11746 intact:EBI-10528|ensemblfungi:YMR043W|uniprotkb:D6VZL8 intact:EBI-10528|ensemblfungi:YMR043W|uniprotkb:D6VZL8 psi-mi:mcm1_yeast(display_long)|uniprotkb:MCM1(gene name)|psi-mi:MCM1(display_short)|uniprotkb:FUN80(gene name synonym)|uniprotkb:YMR043W(locus name)|uniprotkb:YM9532.08(orf name)|uniprotkb:GRM/PRTF protein(gene name synonym) psi-mi:mcm1_yeast(display_long)|uniprotkb:MCM1(gene name)|psi-mi:MCM1(display_short)|uniprotkb:FUN80(gene name synonym)|uniprotkb:YMR043W(locus name)|uniprotkb:YM9532.08(orf name)|uniprotkb:GRM/PRTF protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321519|imex:IM-26944-265 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0044377"(RNA polymerase II cis-regulatory region sequence-specific DNA binding, bending)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR002100(Transcription factor, MADS-box)|interpro:IPR033897|interpro:IPR036879|go:"GO:0043565"(sequence-specific DNA binding)|rcsb pdb:1MNM|reactome:R-SCE-9031628|ensemblfungi:YMR043W(gene)|ensemblfungi:YMR043W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001197"(positive regulation of mating-type specific transcription from RNA polymerase II promoter)|go:"GO:0001198"(negative regulation of mating-type specific transcription from RNA polymerase II promoter)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006525"(arginine metabolic process)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0031494"(regulation of mating type switching)|refseq:NP_013757.1|sgd:S000004646|mint:P11746|dip:DIP-72N|ensemblgenomes:YMR043W(identity) go:"GO:0044377"(RNA polymerase II cis-regulatory region sequence-specific DNA binding, bending)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR002100(Transcription factor, MADS-box)|interpro:IPR033897|interpro:IPR036879|go:"GO:0043565"(sequence-specific DNA binding)|rcsb pdb:1MNM|reactome:R-SCE-9031628|ensemblfungi:YMR043W(gene)|ensemblfungi:YMR043W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001197"(positive regulation of mating-type specific transcription from RNA polymerase II promoter)|go:"GO:0001198"(negative regulation of mating-type specific transcription from RNA polymerase II promoter)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006525"(arginine metabolic process)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0031494"(regulation of mating type switching)|refseq:NP_013757.1|sgd:S000004646|mint:P11746|dip:DIP-72N|ensemblgenomes:YMR043W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:pwq9qbbdOsicNDlNm5d4z89Jpbk559292 rogid:pwq9qbbdOsicNDlNm5d4z89Jpbk559292 rigid:VUImuOfoxhsEd4vNL3a1/aP6cko false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33760 uniprotkb:P33760 intact:EBI-13178|uniprotkb:D6W0L8|ensemblfungi:YNL329C intact:EBI-13178|uniprotkb:D6W0L8|ensemblfungi:YNL329C psi-mi:pex6_yeast(display_long)|uniprotkb:PEX6(gene name)|psi-mi:PEX6(display_short)|uniprotkb:PAS8(gene name synonym)|uniprotkb:YNL329C(locus name)|uniprotkb:N0310(orf name)|uniprotkb:Peroxin-6(gene name synonym)|uniprotkb:Peroxisome biosynthesis protein PAS8(gene name synonym)|uniprotkb:Peroxisomal assembly protein 8(gene name synonym) psi-mi:pex6_yeast(display_long)|uniprotkb:PEX6(gene name)|psi-mi:PEX6(display_short)|uniprotkb:PAS8(gene name synonym)|uniprotkb:YNL329C(locus name)|uniprotkb:N0310(orf name)|uniprotkb:Peroxin-6(gene name synonym)|uniprotkb:Peroxisome biosynthesis protein PAS8(gene name synonym)|uniprotkb:Peroxisomal assembly protein 8(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321507|imex:IM-26944-503 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014070.1|sgd:S000005273|mint:P33760|dip:DIP-2621N|ensemblfungi:YNL329C(gene)|ensemblfungi:YNL329C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0016562"(protein import into peroxisome matrix, receptor recycling)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0043335"(protein unfolding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|ensemblgenomes:YNL329C(identity) refseq:NP_014070.1|sgd:S000005273|mint:P33760|dip:DIP-2621N|ensemblfungi:YNL329C(gene)|ensemblfungi:YNL329C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0016562"(protein import into peroxisome matrix, receptor recycling)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0043335"(protein unfolding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR027417|ensemblgenomes:YNL329C(identity) - crc64:736FECB57BBFF8F8 crc64:736FECB57BBFF8F8 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:vonluDQS+We5JMYERfce8BzCIVk559292 rogid:vonluDQS+We5JMYERfce8BzCIVk559292 rigid:MZdMVs0sQqofI8cMUfC3q18BjD4 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06245 uniprotkb:P06245 intact:EBI-9465|ensemblfungi:YPL203W|uniprotkb:D6W3G6 intact:EBI-9465|ensemblfungi:YPL203W|uniprotkb:D6W3G6 psi-mi:kapb_yeast(display_long)|uniprotkb:YPL203W(locus name)|uniprotkb:TPK2(gene name)|psi-mi:TPK2(display_short)|uniprotkb:PKA2(gene name synonym)|uniprotkb:YKR1(gene name synonym) psi-mi:kapb_yeast(display_long)|uniprotkb:YPL203W(locus name)|uniprotkb:TPK2(gene name)|psi-mi:TPK2(display_short)|uniprotkb:PKA2(gene name synonym)|uniprotkb:YKR1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321495|imex:IM-26944-405 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL203W(gene)|ensemblfungi:YPL203W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000766"(negative regulation of cytoplasmic translation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:NP_015121.1|sgd:S000006124|mint:P06245|dip:DIP-549N|ensemblgenomes:YPL203W(identity) ensemblfungi:YPL203W(gene)|ensemblfungi:YPL203W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000766"(negative regulation of cytoplasmic translation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:NP_015121.1|sgd:S000006124|mint:P06245|dip:DIP-549N|ensemblgenomes:YPL203W(identity) - crc64:1BC255C6D0F33137 crc64:1BC255C6D0F33137 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:9Lh+GL9j37UYnEst/qBIiSKPMd4559292 rogid:9Lh+GL9j37UYnEst/qBIiSKPMd4559292 rigid:Tt7rU7m7GOxZgmuTr6dhnkwwx2U false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q05031 uniprotkb:Q05031 intact:EBI-27512|uniprotkb:D6W064|ensemblfungi:YMR238W intact:EBI-27512|uniprotkb:D6W064|ensemblfungi:YMR238W psi-mi:dfg5_yeast(display_long)|uniprotkb:DFG5(gene name)|psi-mi:DFG5(display_short)|uniprotkb:YMR238W(locus name)|uniprotkb:YM9959.20(orf name)|uniprotkb:Endo-alpha-1->6-D-mannanase DFG5(gene name synonym) psi-mi:dfg5_yeast(display_long)|uniprotkb:DFG5(gene name)|psi-mi:DFG5(display_short)|uniprotkb:YMR238W(locus name)|uniprotkb:YM9959.20(orf name)|uniprotkb:Endo-alpha-1->6-D-mannanase DFG5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321483|imex:IM-26944-259 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q05031|refseq:NP_013965.1|sgd:S000004851|dip:DIP-2739N|ensemblfungi:YMR238W(gene)|ensemblfungi:YMR238W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007117"(budding cell bud growth)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008496"(mannan endo-1,6-alpha-mannosidase activity)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0016052"(carbohydrate catabolic process)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0071555"(cell wall organization)|interpro:IPR005198(Glycoside hydrolase, family 76)|interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR014480(Mannan endo-1,6-alpha-mannosidase)|ensemblgenomes:YMR238W(identity) mint:Q05031|refseq:NP_013965.1|sgd:S000004851|dip:DIP-2739N|ensemblfungi:YMR238W(gene)|ensemblfungi:YMR238W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007117"(budding cell bud growth)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008496"(mannan endo-1,6-alpha-mannosidase activity)|go:"GO:0009272"(fungal-type cell wall biogenesis)|go:"GO:0016052"(carbohydrate catabolic process)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0071555"(cell wall organization)|interpro:IPR005198(Glycoside hydrolase, family 76)|interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR014480(Mannan endo-1,6-alpha-mannosidase)|ensemblgenomes:YMR238W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:nnHGptBCE3g8JbHRaiJvIbe4Nw8559292 rogid:nnHGptBCE3g8JbHRaiJvIbe4Nw8559292 rigid:Az3BZXVhjJvEfE0SAlzlE92QHKY false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P22517 uniprotkb:P22517 intact:EBI-9600|ensemblfungi:YOL016C|uniprotkb:D6W250 intact:EBI-9600|ensemblfungi:YOL016C|uniprotkb:D6W250 psi-mi:kcc2_yeast(display_long)|uniprotkb:CMK2(gene name)|psi-mi:CMK2(display_short)|uniprotkb:YOL016C(locus name) psi-mi:kcc2_yeast(display_long)|uniprotkb:CMK2(gene name)|psi-mi:CMK2(display_short)|uniprotkb:YOL016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321471|imex:IM-26944-583 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOL016C(gene)|ensemblfungi:YOL016C_mRNA(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:NP_014626.1|sgd:S000005376|mint:P22517|dip:DIP-2306N|ensemblgenomes:YOL016C(identity) ensemblfungi:YOL016C(gene)|ensemblfungi:YOL016C_mRNA(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:NP_014626.1|sgd:S000005376|mint:P22517|dip:DIP-2306N|ensemblgenomes:YOL016C(identity) - crc64:5990740B980B8312 crc64:5990740B980B8312 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:9rqj712UWeuB8giYeIUudtnPTM0559292 rogid:9rqj712UWeuB8giYeIUudtnPTM0559292 rigid:NUllddVd3+LoNWNR2REnDLWcgCA false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19454 uniprotkb:P19454 intact:EBI-9548|ensemblfungi:YOR061W|uniprotkb:D6W2C4 intact:EBI-9548|ensemblfungi:YOR061W|uniprotkb:D6W2C4 psi-mi:csk22_yeast(display_long)|uniprotkb:CKA2(gene name)|psi-mi:CKA2(display_short)|uniprotkb:YOR29-12(orf name)|uniprotkb:YOR061W(locus name) psi-mi:csk22_yeast(display_long)|uniprotkb:CKA2(gene name)|psi-mi:CKA2(display_short)|uniprotkb:YOR29-12(orf name)|uniprotkb:YOR061W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321459|imex:IM-26944-499 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR061W(gene)|ensemblfungi:YOR061W_mRNA(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|go:"GO:0006359"(regulation of transcription by RNA polymerase III)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007535"(donor selection)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0034456"(UTP-C complex)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-2514853|reactome:R-SCE-6804756|reactome:R-SCE-8934903|reactome:R-SCE-8948751|refseq:NP_014704.1|sgd:S000005587|mint:P19454|dip:DIP-1038N|ensemblgenomes:YOR061W(identity) ensemblfungi:YOR061W(gene)|ensemblfungi:YOR061W_mRNA(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|go:"GO:0006359"(regulation of transcription by RNA polymerase III)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007535"(donor selection)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0034456"(UTP-C complex)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-SCE-2514853|reactome:R-SCE-6804756|reactome:R-SCE-8934903|reactome:R-SCE-8948751|refseq:NP_014704.1|sgd:S000005587|mint:P19454|dip:DIP-1038N|ensemblgenomes:YOR061W(identity) - crc64:30E214BD852824D0 crc64:30E214BD852824D0 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:E39eioYivVEqVSUhL99a2iGvisg559292 rogid:E39eioYivVEqVSUhL99a2iGvisg559292 rigid:OWBXpRt62sMp4zU3SNQnCgKiaTc false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17883 uniprotkb:P17883 intact:EBI-1861|uniprotkb:Q06585|ensemblfungi:YPR189W intact:EBI-1861|uniprotkb:Q06585|ensemblfungi:YPR189W psi-mi:ski3_yeast(display_long)|uniprotkb:SKI3(gene name)|psi-mi:SKI3(display_short)|uniprotkb:P9677.7(orf name)|uniprotkb:YPR189W(locus name) psi-mi:ski3_yeast(display_long)|uniprotkb:SKI3(gene name)|psi-mi:SKI3(display_short)|uniprotkb:P9677.7(orf name)|uniprotkb:YPR189W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321447|imex:IM-26944-257 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000006393|refseq:NP_015515.1|dip:DIP-6379N|mint:P17883|ensemblfungi:YPR189W(gene)|ensemblfungi:YPR189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0051607"(defense response to virus)|go:"GO:0055087"(Ski complex)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039226|interpro:IPR040962|rcsb pdb:4BUJ|rcsb pdb:5MC6|reactome:R-SCE-429958|ensemblgenomes:YPR189W(identity) sgd:S000006393|refseq:NP_015515.1|dip:DIP-6379N|mint:P17883|ensemblfungi:YPR189W(gene)|ensemblfungi:YPR189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0051607"(defense response to virus)|go:"GO:0055087"(Ski complex)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039226|interpro:IPR040962|rcsb pdb:4BUJ|rcsb pdb:5MC6|reactome:R-SCE-429958|ensemblgenomes:YPR189W(identity) - crc64:18FFF78D7CA5A6E4 crc64:18FFF78D7CA5A6E4 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:wjMKcbtN38crXFX7hQgZ0Bz475Y559292 rogid:wjMKcbtN38crXFX7hQgZ0Bz475Y559292 rigid:46khcBrY1yP0nLGxzy0cd4aWxEo false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11076 uniprotkb:P11076 intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W intact:EBI-2816|uniprotkb:D6VRG1|ensemblfungi:YDL192W psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:arf1_yeast(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short)|uniprotkb:D1244(orf name)|uniprotkb:YDL192W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321699|imex:IM-26944-507 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438|ensemblgenomes:YDL192W(identity) refseq:NP_010089.1|sgd:S000002351|dip:DIP-2213N|mint:P11076|ensemblfungi:YDL192W(gene)|ensemblfungi:YDL192W_mRNA(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|rcsb pdb:2K5U|rcsb pdb:2KSQ|rcsb pdb:3TJZ|rcsb pdb:4Q66|rcsb pdb:5A1U|rcsb pdb:5A1V|rcsb pdb:5A1W|rcsb pdb:5A1X|rcsb pdb:5A1Y|rcsb pdb:5NZR|rcsb pdb:5NZS|rcsb pdb:5NZT|rcsb pdb:5NZU|rcsb pdb:5NZV|reactome:R-SCE-1660514|reactome:R-SCE-199992|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-6811438|ensemblgenomes:YDL192W(identity) - crc64:796859026AC63CC0 crc64:796859026AC63CC0 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 rogid:IX/zwfWagjieSKB1ShJ9P0kq1ZE559292 rigid:VBCfeD7q83udd5Bm8HWYgk9x2Ig false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P01097 uniprotkb:P01097 intact:EBI-8874|ensemblfungi:YDL181W|uniprotkb:D6VRH1 intact:EBI-8874|ensemblfungi:YDL181W|uniprotkb:D6VRH1 psi-mi:atif_yeast(display_long)|uniprotkb:INH1(gene name)|psi-mi:INH1(display_short)|uniprotkb:ATP synthase F1 subunit epsilon(gene name synonym)|uniprotkb:D1305(orf name)|uniprotkb:YDL181W(locus name) psi-mi:atif_yeast(display_long)|uniprotkb:INH1(gene name)|psi-mi:INH1(display_short)|uniprotkb:ATP synthase F1 subunit epsilon(gene name synonym)|uniprotkb:D1305(orf name)|uniprotkb:YDL181W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321687|imex:IM-26944-591 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDL181W(gene)|ensemblfungi:YDL181W_mRNA(transcript)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0042030"(ATPase inhibitor activity)|interpro:IPR007648(Mitochondrial ATPase inhibitor, IATP)|rcsb pdb:3ZIA|refseq:NP_010100.1|sgd:S000002340|mint:P01097|dip:DIP-2985N|ensemblgenomes:YDL181W(identity) ensemblfungi:YDL181W(gene)|ensemblfungi:YDL181W_mRNA(transcript)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0042030"(ATPase inhibitor activity)|interpro:IPR007648(Mitochondrial ATPase inhibitor, IATP)|rcsb pdb:3ZIA|refseq:NP_010100.1|sgd:S000002340|mint:P01097|dip:DIP-2985N|ensemblgenomes:YDL181W(identity) - crc64:E1AF73A47F63CE58 crc64:E1AF73A47F63CE58 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:3wsu4TOLAZdm97Kfhla8l4UKFEk559292 rogid:3wsu4TOLAZdm97Kfhla8l4UKFEk559292 rigid:PaQTuu5pmvWPcm5thB+Zx5CqA+4 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03790 uniprotkb:Q03790 intact:EBI-27321|uniprotkb:D6VZX4|ensemblfungi:YMR153W intact:EBI-27321|uniprotkb:D6VZX4|ensemblfungi:YMR153W psi-mi:nup53_yeast(display_long)|uniprotkb:Nuclear pore protein NUP53(gene name synonym)|uniprotkb:NUP53(gene name)|psi-mi:NUP53(display_short)|uniprotkb:YMR153W(locus name)|uniprotkb:YM8520.02(orf name) psi-mi:nup53_yeast(display_long)|uniprotkb:Nuclear pore protein NUP53(gene name synonym)|uniprotkb:NUP53(gene name)|psi-mi:NUP53(display_short)|uniprotkb:YMR153W(locus name)|uniprotkb:YM8520.02(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321675|imex:IM-26944-689 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013873.1|sgd:S000004762|dip:DIP-1467N|ensemblfungi:YMR153W(gene)|ensemblfungi:YMR153W_mRNA(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|go:"GO:0060188"(regulation of protein desumoylation)|go:"GO:0072417"(response to spindle checkpoint signaling)|interpro:IPR007846(MPPN)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017389(Nucleoporin, NUP53)|interpro:IPR035979|rcsb pdb:3W3Y|rcsb pdb:5UAZ|ensemblgenomes:YMR153W(identity) refseq:NP_013873.1|sgd:S000004762|dip:DIP-1467N|ensemblfungi:YMR153W(gene)|ensemblfungi:YMR153W_mRNA(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|go:"GO:0060188"(regulation of protein desumoylation)|go:"GO:0072417"(response to spindle checkpoint signaling)|interpro:IPR007846(MPPN)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017389(Nucleoporin, NUP53)|interpro:IPR035979|rcsb pdb:3W3Y|rcsb pdb:5UAZ|ensemblgenomes:YMR153W(identity) - crc64:2ECE0C561D27E523 crc64:2ECE0C561D27E523 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:csq2oRFswkgY2JkT+dmz/L7Zpfk559292 rogid:csq2oRFswkgY2JkT+dmz/L7Zpfk559292 rigid:nlLjVD79aNOqvp6SDjMD0NilAJc false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39540 uniprotkb:P39540 intact:EBI-7745012|ensemblfungi:YJL196C|uniprotkb:D6VVZ6|intact:MINT-1357650 intact:EBI-7745012|ensemblfungi:YJL196C|uniprotkb:D6VVZ6|intact:MINT-1357650 psi-mi:elo1_yeast(display_long)|uniprotkb:ELO1(gene name)|psi-mi:ELO1(display_short)|uniprotkb:3-keto acyl-CoA synthase ELO1(gene name synonym)|uniprotkb:Very-long-chain 3-oxoacyl-CoA synthase 1(gene name synonym)|uniprotkb:J0343(orf name)|uniprotkb:YJL196C(locus name) psi-mi:elo1_yeast(display_long)|uniprotkb:ELO1(gene name)|psi-mi:ELO1(display_short)|uniprotkb:3-keto acyl-CoA synthase ELO1(gene name synonym)|uniprotkb:Very-long-chain 3-oxoacyl-CoA synthase 1(gene name synonym)|uniprotkb:J0343(orf name)|uniprotkb:YJL196C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321663|imex:IM-26944-61 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YJL196C(gene)|ensemblfungi:YJL196C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0009922"(fatty acid elongase activity)|go:"GO:0019367"(fatty acid elongation, saturated fatty acid)|go:"GO:0019368"(fatty acid elongation, unsaturated fatty acid)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034625"(fatty acid elongation, monounsaturated fatty acid)|go:"GO:0034626"(fatty acid elongation, polyunsaturated fatty acid)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0102336"(3-oxo-arachidoyl-CoA synthase activity)|go:"GO:0102337"(3-oxo-cerotoyl-CoA synthase activity)|go:"GO:0102338"(3-oxo-lignoceronyl-CoA synthase activity)|go:"GO:0102756"(very-long-chain 3-ketoacyl-CoA synthase activity)|interpro:IPR002076(GNS1/SUR4 membrane protein)|interpro:IPR030457|sgd:S000003732|refseq:NP_012339.1|dip:DIP-8755N|ensemblgenomes:YJL196C(identity) ensemblfungi:YJL196C(gene)|ensemblfungi:YJL196C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0009922"(fatty acid elongase activity)|go:"GO:0019367"(fatty acid elongation, saturated fatty acid)|go:"GO:0019368"(fatty acid elongation, unsaturated fatty acid)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0034625"(fatty acid elongation, monounsaturated fatty acid)|go:"GO:0034626"(fatty acid elongation, polyunsaturated fatty acid)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0102336"(3-oxo-arachidoyl-CoA synthase activity)|go:"GO:0102337"(3-oxo-cerotoyl-CoA synthase activity)|go:"GO:0102338"(3-oxo-lignoceronyl-CoA synthase activity)|go:"GO:0102756"(very-long-chain 3-ketoacyl-CoA synthase activity)|interpro:IPR002076(GNS1/SUR4 membrane protein)|interpro:IPR030457|sgd:S000003732|refseq:NP_012339.1|dip:DIP-8755N|ensemblgenomes:YJL196C(identity) - comment:mint|function:"May be a membrane bound enzyme involved in the highly specific elongation of saturated 14-carbon fatty acids (14:0) to 16-carbon species (16:0)" comment:mint|function:"May be a membrane bound enzyme involved in the highly specific elongation of saturated 14-carbon fatty acids (14:0) to 16-carbon species (16:0)" figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:ZTgAn3eBkLQSYokr0UxYXfg1rqs559292 rogid:ZTgAn3eBkLQSYokr0UxYXfg1rqs559292 rigid:Nm+K989qwH5Ux0EyZpEG75HAm94 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P00890 uniprotkb:P00890 intact:EBI-4708|uniprotkb:D6W1H7|ensemblfungi:YNR001C intact:EBI-4708|uniprotkb:D6W1H7|ensemblfungi:YNR001C psi-mi:cisy1_yeast(display_long)|uniprotkb:CIT1(gene name)|psi-mi:CIT1(display_short)|uniprotkb:GLU3(gene name synonym)|uniprotkb:LYS6(gene name synonym)|uniprotkb:YNR001C(locus name)|uniprotkb:N2019(orf name) psi-mi:cisy1_yeast(display_long)|uniprotkb:CIT1(gene name)|psi-mi:CIT1(display_short)|uniprotkb:GLU3(gene name synonym)|uniprotkb:LYS6(gene name synonym)|uniprotkb:YNR001C(locus name)|uniprotkb:N2019(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321651|imex:IM-26944-337 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014398.1|sgd:S000005284|dip:DIP-4597N|reactome:R-SCE-71403|ensemblfungi:YNR001C(gene)|ensemblfungi:YNR001C_mRNA(transcript)|go:"GO:0004108"("citrate (Si)-synthase activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0036440"(citrate synthase activity)|go:"GO:0046356"(acetyl-CoA catabolic process)|interpro:IPR002020(Citrate synthase-like)|interpro:IPR010109(Citrate synthase, eukaryotic)|interpro:IPR016142(Citrate synthase-like, large alpha subdomain)|interpro:IPR016143(Citrate synthase-like, small alpha subdomain)|interpro:IPR019810|interpro:IPR036969|ensemblgenomes:YNR001C(identity) refseq:NP_014398.1|sgd:S000005284|dip:DIP-4597N|reactome:R-SCE-71403|ensemblfungi:YNR001C(gene)|ensemblfungi:YNR001C_mRNA(transcript)|go:"GO:0004108"("citrate (Si)-synthase activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0036440"(citrate synthase activity)|go:"GO:0046356"(acetyl-CoA catabolic process)|interpro:IPR002020(Citrate synthase-like)|interpro:IPR010109(Citrate synthase, eukaryotic)|interpro:IPR016142(Citrate synthase-like, large alpha subdomain)|interpro:IPR016143(Citrate synthase-like, small alpha subdomain)|interpro:IPR019810|interpro:IPR036969|ensemblgenomes:YNR001C(identity) - crc64:280661B1CB248F14 crc64:280661B1CB248F14 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:qu+gkZqDt/uACIXboVEnpdGvN+A559292 rogid:qu+gkZqDt/uACIXboVEnpdGvN+A559292 rigid:AF1Fsj/bim9ZPXK6cdWRF1IADGs false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12034 uniprotkb:Q12034 intact:EBI-17335|uniprotkb:D6VTD6|uniprotkb:E9P8Z6|ensemblfungi:YDR515W intact:EBI-17335|uniprotkb:D6VTD6|uniprotkb:E9P8Z6|ensemblfungi:YDR515W psi-mi:slf1_yeast(display_long)|uniprotkb:D9719.20(orf name)|uniprotkb:YDR515W(locus name)|uniprotkb:SLF1(gene name)|psi-mi:SLF1(display_short) psi-mi:slf1_yeast(display_long)|uniprotkb:D9719.20(orf name)|uniprotkb:YDR515W(locus name)|uniprotkb:SLF1(gene name)|psi-mi:SLF1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321639|imex:IM-26944-589 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010803.3|sgd:S000002923|ensemblfungi:YDR515W(gene)|ensemblfungi:YDR515W_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006417"(regulation of translation)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0010494"(cytoplasmic stress granule)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390|dip:DIP-2938N|mint:Q12034|ensemblgenomes:YDR515W(identity) refseq:NP_010803.3|sgd:S000002923|ensemblfungi:YDR515W(gene)|ensemblfungi:YDR515W_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006417"(regulation of translation)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0010494"(cytoplasmic stress granule)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390|dip:DIP-2938N|mint:Q12034|ensemblgenomes:YDR515W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:XBjQud6beJKzvJeWksARACuczoY559292 rogid:XBjQud6beJKzvJeWksARACuczoY559292 rigid:hIIe8vYsIjfrh1thYPjYS67evBs false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48813 uniprotkb:P48813 intact:EBI-7758|uniprotkb:D6VTD0|ensemblfungi:YDR508C intact:EBI-7758|uniprotkb:D6VTD0|ensemblfungi:YDR508C psi-mi:gnp1_yeast(display_long)|uniprotkb:GNP1(gene name)|psi-mi:GNP1(display_short)|uniprotkb:D9719.14(orf name)|uniprotkb:YDR508C(locus name) psi-mi:gnp1_yeast(display_long)|uniprotkb:GNP1(gene name)|psi-mi:GNP1(display_short)|uniprotkb:D9719.14(orf name)|uniprotkb:YDR508C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321627|imex:IM-26944-59 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010796.1|sgd:S000002916|dip:DIP-1616N|ensemblfungi:YDR508C(gene)|ensemblfungi:YDR508C_mRNA(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015193"(L-proline transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:0098718"(serine import across plasma membrane)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region)|ensemblgenomes:YDR508C(identity) refseq:NP_010796.1|sgd:S000002916|dip:DIP-1616N|ensemblfungi:YDR508C(gene)|ensemblfungi:YDR508C_mRNA(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015193"(L-proline transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0055085"(transmembrane transport)|go:"GO:0071944"(cell periphery)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:0098718"(serine import across plasma membrane)|interpro:IPR004762(Amino acid permease, fungi)|interpro:IPR004840(Amino acid permease, conserved site)|interpro:IPR004841(Amino acid permease-associated region)|ensemblgenomes:YDR508C(identity) - crc64:9A5ED9CF7C1DD977 crc64:9A5ED9CF7C1DD977 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:ViyFFdYNUSkZx7fowfIivmwwM/k559292 rogid:ViyFFdYNUSkZx7fowfIivmwwM/k559292 rigid:mhhGrgy7tMQUXfpDct+1mznQQDk false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53144 uniprotkb:P53144 intact:EBI-23891|uniprotkb:D6VU44|ensemblfungi:YGL101W intact:EBI-23891|uniprotkb:D6VU44|ensemblfungi:YGL101W psi-mi:ygk1_yeast(display_long)|uniprotkb:YGK1(gene name)|psi-mi:YGK1(display_short)|uniprotkb:YGL101W(locus name) psi-mi:ygk1_yeast(display_long)|uniprotkb:YGK1(gene name)|psi-mi:YGK1(display_short)|uniprotkb:YGL101W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321615|imex:IM-26944-57 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011414.1|sgd:S000003069|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR039356|rcsb pdb:5YOX|ensemblfungi:YGL101W(gene)|ensemblfungi:YGL101W_mRNA(transcript)|go:"GO:0002953"(5'-deoxynucleotidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009159"(deoxyribonucleoside monophosphate catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050484"(GMP 5'-nucleotidase activity)|ensemblgenomes:YGL101W(identity) refseq:NP_011414.1|sgd:S000003069|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR039356|rcsb pdb:5YOX|ensemblfungi:YGL101W(gene)|ensemblfungi:YGL101W_mRNA(transcript)|go:"GO:0002953"(5'-deoxynucleotidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009159"(deoxyribonucleoside monophosphate catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050484"(GMP 5'-nucleotidase activity)|ensemblgenomes:YGL101W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:cVMRgc1Y550pp6sGxs0r8s2eq70559292 rogid:cVMRgc1Y550pp6sGxs0r8s2eq70559292 rigid:kikFXDCi/OQyxRKOGqLWCQxH1No false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P11154 uniprotkb:P11154 intact:EBI-14358|uniprotkb:D6VU79|ensemblfungi:YGL062W intact:EBI-14358|uniprotkb:D6VU79|ensemblfungi:YGL062W psi-mi:pyc1_yeast(display_long)|uniprotkb:PYV(gene name synonym)|uniprotkb:YGL062W(locus name)|uniprotkb:PYC1(gene name)|psi-mi:PYC1(display_short)|uniprotkb:Pyruvic carboxylase 1(gene name synonym) psi-mi:pyc1_yeast(display_long)|uniprotkb:PYV(gene name synonym)|uniprotkb:YGL062W(locus name)|uniprotkb:PYC1(gene name)|psi-mi:PYC1(display_short)|uniprotkb:Pyruvic carboxylase 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321603|imex:IM-26944-587 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL062W(gene)|go:"GO:0004736"(pyruvate carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0009374"(biotin binding)|go:"GO:0046872"(metal ion binding)|ensemblfungi:YGL062W_mRNA(transcript)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR001882(Biotin-binding site)|interpro:IPR003379(Conserved carboxylase region)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR005930(Pyruvate carboxylase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016185(PreATP-grasp-like fold)|reactome:R-SCE-196780|reactome:R-SCE-70263|refseq:NP_011453.1|sgd:S000003030|mint:P11154|dip:DIP-6425N|ensemblgenomes:YGL062W(identity) ensemblfungi:YGL062W(gene)|go:"GO:0004736"(pyruvate carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0009374"(biotin binding)|go:"GO:0046872"(metal ion binding)|ensemblfungi:YGL062W_mRNA(transcript)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR001882(Biotin-binding site)|interpro:IPR003379(Conserved carboxylase region)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR005930(Pyruvate carboxylase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016185(PreATP-grasp-like fold)|reactome:R-SCE-196780|reactome:R-SCE-70263|refseq:NP_011453.1|sgd:S000003030|mint:P11154|dip:DIP-6425N|ensemblgenomes:YGL062W(identity) - crc64:BC7110A8AFB23E04 crc64:BC7110A8AFB23E04 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:YleVCYfwUsqRJy5ua02EuklzpkQ559292 rogid:YleVCYfwUsqRJy5ua02EuklzpkQ559292 rigid:ZIjXOr626Pnl0f5fNDNPLf2rnNs false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O13516 uniprotkb:O13516 intact:EBI-16176|ensemblfungi:YPL081W|uniprotkb:D6W3T6 intact:EBI-16176|ensemblfungi:YPL081W|uniprotkb:D6W3T6 psi-mi:rs9a_yeast(display_long)|uniprotkb:RPS9A(gene name)|psi-mi:RPS9A(display_short)|uniprotkb:RPS13A(gene name synonym)|uniprotkb:YS11A(gene name synonym)|uniprotkb:YPL081W(locus name)|uniprotkb:S13(gene name synonym)|uniprotkb:YS11(gene name synonym)|uniprotkb:RP21(gene name synonym)|uniprotkb:YP28(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS4-A(gene name synonym) psi-mi:rs9a_yeast(display_long)|uniprotkb:RPS9A(gene name)|psi-mi:RPS9A(display_short)|uniprotkb:RPS13A(gene name synonym)|uniprotkb:YS11A(gene name synonym)|uniprotkb:YPL081W(locus name)|uniprotkb:S13(gene name synonym)|uniprotkb:YS11(gene name synonym)|uniprotkb:RP21(gene name synonym)|uniprotkb:YP28(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS4-A(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321591|imex:IM-26944-585 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL081W(gene)|ensemblfungi:YPL081W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0019843"(rRNA binding)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0045903"(positive regulation of translational fidelity)|rcsb pdb:1K5X|rcsb pdb:3J6X|rcsb pdb:3J6Y|rcsb pdb:3J78|rcsb pdb:4U3M|rcsb pdb:4U3N|rcsb pdb:4U3U|rcsb pdb:4U4N|rcsb pdb:4U4O|rcsb pdb:4U4Q|rcsb pdb:4U4R|rcsb pdb:4U4U|rcsb pdb:4U4Y|rcsb pdb:4U4Z|rcsb pdb:4U50|rcsb pdb:4U51|rcsb pdb:4U52|rcsb pdb:4U53|rcsb pdb:3J77|rcsb pdb:4U55|rcsb pdb:4U56|rcsb pdb:4U6F|rcsb pdb:6Z6K|rcsb pdb:6ZCE|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:6ZQG|rcsb pdb:6ZU9|rcsb pdb:6ZVI|rcsb pdb:7A1G|rcsb pdb:7AJT|rcsb pdb:7AJU|rcsb pdb:7B7D|rcsb pdb:7NRC|rcsb pdb:7NRD|rcsb pdb:4V6I|rcsb pdb:4V7R|rcsb pdb:4V88|rcsb pdb:4V8Y|rcsb pdb:4V8Z|rcsb pdb:4V92|rcsb pdb:5DAT|rcsb pdb:5DC3|rcsb pdb:5DGE|rcsb pdb:5DGF|rcsb pdb:5DGV|rcsb pdb:5FCI|rcsb pdb:5FCJ|rcsb pdb:5I4L|rcsb pdb:5JPQ|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:5LL6|rcsb pdb:4V4B|rcsb pdb:5LYB|rcsb pdb:5M1J|rcsb pdb:5MC6|rcsb pdb:5MEI|rcsb pdb:5NDG|rcsb pdb:5NDV|rcsb pdb:5NDW|rcsb pdb:5OBM|rcsb pdb:5ON6|rcsb pdb:5TBW|rcsb pdb:5TGA|rcsb pdb:5TGM|rcsb pdb:5TZS|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6EML|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6Q8Y|rcsb pdb:6RBD|rcsb pdb:6RBE|rcsb pdb:6S47|rcsb pdb:6SNT|rcsb pdb:6SV4|rcsb pdb:6FAI|rcsb pdb:6T4Q|rcsb pdb:6T7I|rcsb pdb:6GQ1|rcsb pdb:6T7T|rcsb pdb:6T83|rcsb pdb:6GQB|rcsb pdb:6GQV|rcsb pdb:6HHQ|rcsb pdb:6I7O|rcsb pdb:6KE6|rcsb pdb:6TB3|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6TNU|rcsb pdb:6WDR|rcsb pdb:6XIQ|rcsb pdb:6XIR|rcsb pdb:6Y7C|rcsb pdb:6Z6J|refseq:NP_015244.1|sgd:S000006002|interpro:IPR022801|interpro:IPR005710(Ribosomal protein S4/S9, eukaryotic/archaeal)|interpro:IPR001912(Ribosomal protein S4)|interpro:IPR018079|interpro:IPR002942(RNA-binding S4)|mint:O13516|interpro:IPR036986|ensemblgenomes:YPL081W(identity) ensemblfungi:YPL081W(gene)|ensemblfungi:YPL081W_mRNA(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0019843"(rRNA binding)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|go:"GO:0045903"(positive regulation of translational fidelity)|rcsb pdb:1K5X|rcsb pdb:3J6X|rcsb pdb:3J6Y|rcsb pdb:3J78|rcsb pdb:4U3M|rcsb pdb:4U3N|rcsb pdb:4U3U|rcsb pdb:4U4N|rcsb pdb:4U4O|rcsb pdb:4U4Q|rcsb pdb:4U4R|rcsb pdb:4U4U|rcsb pdb:4U4Y|rcsb pdb:4U4Z|rcsb pdb:4U50|rcsb pdb:4U51|rcsb pdb:4U52|rcsb pdb:4U53|rcsb pdb:3J77|rcsb pdb:4U55|rcsb pdb:4U56|rcsb pdb:4U6F|rcsb pdb:6Z6K|rcsb pdb:6ZCE|rcsb pdb:6ZQA|rcsb pdb:6ZQB|rcsb pdb:6ZQC|rcsb pdb:6ZQD|rcsb pdb:6ZQE|rcsb pdb:6ZQF|rcsb pdb:6ZQG|rcsb pdb:6ZU9|rcsb pdb:6ZVI|rcsb pdb:7A1G|rcsb pdb:7AJT|rcsb pdb:7AJU|rcsb pdb:7B7D|rcsb pdb:7NRC|rcsb pdb:7NRD|rcsb pdb:4V6I|rcsb pdb:4V7R|rcsb pdb:4V88|rcsb pdb:4V8Y|rcsb pdb:4V8Z|rcsb pdb:4V92|rcsb pdb:5DAT|rcsb pdb:5DC3|rcsb pdb:5DGE|rcsb pdb:5DGF|rcsb pdb:5DGV|rcsb pdb:5FCI|rcsb pdb:5FCJ|rcsb pdb:5I4L|rcsb pdb:5JPQ|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:5LL6|rcsb pdb:4V4B|rcsb pdb:5LYB|rcsb pdb:5M1J|rcsb pdb:5MC6|rcsb pdb:5MEI|rcsb pdb:5NDG|rcsb pdb:5NDV|rcsb pdb:5NDW|rcsb pdb:5OBM|rcsb pdb:5ON6|rcsb pdb:5TBW|rcsb pdb:5TGA|rcsb pdb:5TGM|rcsb pdb:5TZS|rcsb pdb:5WLC|rcsb pdb:5WYJ|rcsb pdb:5WYK|rcsb pdb:6EML|rcsb pdb:6LQR|rcsb pdb:6LQS|rcsb pdb:6LQT|rcsb pdb:6LQU|rcsb pdb:6LQV|rcsb pdb:6Q8Y|rcsb pdb:6RBD|rcsb pdb:6RBE|rcsb pdb:6S47|rcsb pdb:6SNT|rcsb pdb:6SV4|rcsb pdb:6FAI|rcsb pdb:6T4Q|rcsb pdb:6T7I|rcsb pdb:6GQ1|rcsb pdb:6T7T|rcsb pdb:6T83|rcsb pdb:6GQB|rcsb pdb:6GQV|rcsb pdb:6HHQ|rcsb pdb:6I7O|rcsb pdb:6KE6|rcsb pdb:6TB3|rcsb pdb:6LQP|rcsb pdb:6LQQ|rcsb pdb:6TNU|rcsb pdb:6WDR|rcsb pdb:6XIQ|rcsb pdb:6XIR|rcsb pdb:6Y7C|rcsb pdb:6Z6J|refseq:NP_015244.1|sgd:S000006002|interpro:IPR022801|interpro:IPR005710(Ribosomal protein S4/S9, eukaryotic/archaeal)|interpro:IPR001912(Ribosomal protein S4)|interpro:IPR018079|interpro:IPR002942(RNA-binding S4)|mint:O13516|interpro:IPR036986|ensemblgenomes:YPL081W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:vAdW2QQWeep7eysGfwdrph+099Q559292 rogid:vAdW2QQWeep7eysGfwdrph+099Q559292 rigid:8yide0MjJT8C9zDBrN81lTmfiQo false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12451 uniprotkb:Q12451 intact:EBI-12621|uniprotkb:P89891|uniprotkb:D6VRX1|ensemblfungi:YDL019C intact:EBI-12621|uniprotkb:P89891|uniprotkb:D6VRX1|ensemblfungi:YDL019C psi-mi:osh2_yeast(display_long)|uniprotkb:D2845(orf name)|uniprotkb:YDL019C(locus name)|uniprotkb:OSH2(gene name)|psi-mi:OSH2(display_short) psi-mi:osh2_yeast(display_long)|uniprotkb:D2845(orf name)|uniprotkb:YDL019C(locus name)|uniprotkb:OSH2(gene name)|psi-mi:OSH2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321555|imex:IM-26944-505 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YDL019C(gene)|ensemblfungi:YDL019C_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0035621"(ER to Golgi ceramide transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071944"(cell periphery)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR036770|interpro:IPR037239|reactome:R-SCE-192105|go:"GO:0120015"(sterol transfer activity)|refseq:NP_010265.1|sgd:S000002177|mint:Q12451|dip:DIP-6712N|ensemblgenomes:YDL019C(identity) ensemblfungi:YDL019C(gene)|ensemblfungi:YDL019C_mRNA(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0035621"(ER to Golgi ceramide transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071944"(cell periphery)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR036770|interpro:IPR037239|reactome:R-SCE-192105|go:"GO:0120015"(sterol transfer activity)|refseq:NP_010265.1|sgd:S000002177|mint:Q12451|dip:DIP-6712N|ensemblgenomes:YDL019C(identity) - crc64:D521957460E7F7C3 crc64:D521957460E7F7C3 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:75/WAoxCRsenLJMmbyowdFQ8srs559292 rogid:75/WAoxCRsenLJMmbyowdFQ8srs559292 rigid:bC9opMb6B9S6usR45fvidxFGZZk false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q04947 uniprotkb:Q04947 intact:EBI-38020|uniprotkb:D6VSL4|ensemblfungi:YDR233C intact:EBI-38020|uniprotkb:D6VSL4|ensemblfungi:YDR233C psi-mi:rtn1_yeast(display_long)|uniprotkb:RTN1(gene name)|psi-mi:RTN1(display_short)|uniprotkb:YDR233C(locus name) psi-mi:rtn1_yeast(display_long)|uniprotkb:RTN1(gene name)|psi-mi:RTN1(display_short)|uniprotkb:YDR233C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321711|imex:IM-26944-593 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002641|refseq:NP_010519.3|dip:DIP-4090N|mint:Q04947|ensemblfungi:YDR233C(gene)|ensemblfungi:YDR233C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032581"(ER-dependent peroxisome organization)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0071458"(integral component of cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0071788"(endoplasmic reticulum tubular network maintenance)|go:"GO:0071944"(cell periphery)|interpro:IPR003388(Reticulon)|ensemblgenomes:YDR233C(identity) sgd:S000002641|refseq:NP_010519.3|dip:DIP-4090N|mint:Q04947|ensemblfungi:YDR233C(gene)|ensemblfungi:YDR233C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032581"(ER-dependent peroxisome organization)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0048309"(endoplasmic reticulum inheritance)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0071458"(integral component of cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0071788"(endoplasmic reticulum tubular network maintenance)|go:"GO:0071944"(cell periphery)|interpro:IPR003388(Reticulon)|ensemblgenomes:YDR233C(identity) - crc64:245575E65D3C2193 crc64:245575E65D3C2193 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:EEXsl6gyB0GVuwAEwN1AAOF8h1E559292 rogid:EEXsl6gyB0GVuwAEwN1AAOF8h1E559292 rigid:VCEbDXf9mw4em77grnKrc9lZpDQ false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12416 uniprotkb:Q12416 intact:EBI-29963|uniprotkb:D6W2E5|ensemblfungi:YOR083W intact:EBI-29963|uniprotkb:D6W2E5|ensemblfungi:YOR083W psi-mi:whi5_yeast(display_long)|uniprotkb:WHI5(gene name)|psi-mi:WHI5(display_short)|uniprotkb:YOR3116W(orf name)|uniprotkb:YOR083W(locus name) psi-mi:whi5_yeast(display_long)|uniprotkb:WHI5(gene name)|psi-mi:WHI5(display_short)|uniprotkb:YOR3116W(orf name)|uniprotkb:YOR083W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21322179|imex:IM-26944-79 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014726.1|sgd:S000005609|dip:DIP-8958N|mint:Q12416|ensemblfungi:YOR083W(gene)|ensemblfungi:YOR083W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0033309"(SBF transcription complex)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071930"(negative regulation of transcription involved in G1/S transition of mitotic cell cycle)|interpro:IPR013734(Nrm1)|interpro:IPR039198|ensemblgenomes:YOR083W(identity) refseq:NP_014726.1|sgd:S000005609|dip:DIP-8958N|mint:Q12416|ensemblfungi:YOR083W(gene)|ensemblfungi:YOR083W_mRNA(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0033309"(SBF transcription complex)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071930"(negative regulation of transcription involved in G1/S transition of mitotic cell cycle)|interpro:IPR013734(Nrm1)|interpro:IPR039198|ensemblgenomes:YOR083W(identity) - crc64:013A41AC5DC1975F crc64:013A41AC5DC1975F figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:Sz51DYEnxRj6Vuba1PxIAaTenV0559292 rogid:Sz51DYEnxRj6Vuba1PxIAaTenV0559292 rigid:c6Y8ELL+ivJfoW9eirbwPbbuscA false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34761 uniprotkb:P34761 intact:EBI-20537|uniprotkb:D6W0Z0|ensemblfungi:YNL197C intact:EBI-20537|uniprotkb:D6W0Z0|ensemblfungi:YNL197C psi-mi:whi3_yeast(display_long)|uniprotkb:WHI3(gene name)|psi-mi:WHI3(display_short)|uniprotkb:N1382(orf name)|uniprotkb:YNL197C(locus name) psi-mi:whi3_yeast(display_long)|uniprotkb:WHI3(gene name)|psi-mi:WHI3(display_short)|uniprotkb:N1382(orf name)|uniprotkb:YNL197C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321723|imex:IM-26944-167 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014202.1|sgd:S000005141|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|ensemblfungi:YNL197C(gene)|ensemblfungi:YNL197C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0032106"(positive regulation of response to extracellular stimulus)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0061013"(regulation of mRNA catabolic process)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071554"(cell wall organization or biogenesis)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:P34761|ensemblgenomes:YNL197C(identity) refseq:NP_014202.1|sgd:S000005141|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|ensemblfungi:YNL197C(gene)|ensemblfungi:YNL197C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0032106"(positive regulation of response to extracellular stimulus)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0061013"(regulation of mRNA catabolic process)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071554"(cell wall organization or biogenesis)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:P34761|ensemblgenomes:YNL197C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:Xpn0uJiaylcupy9qYDLa0V++z6A559292 rogid:Xpn0uJiaylcupy9qYDLa0V++z6A559292 rigid:F8XpfH7zOkrMD3MOKXIQ22bQnWw false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08438 uniprotkb:Q08438 intact:EBI-30482|uniprotkb:O00019|uniprotkb:D6W2B8|ensemblfungi:YOR054C intact:EBI-30482|uniprotkb:O00019|uniprotkb:D6W2B8|ensemblfungi:YOR054C psi-mi:vhs3_yeast(display_long)|uniprotkb:Viable in a HAL3 SIT4 background protein 3(gene name synonym)|uniprotkb:VHS3(gene name)|psi-mi:VHS3(display_short)|uniprotkb:YOR054C(locus name)|uniprotkb:YOR29-05(orf name) psi-mi:vhs3_yeast(display_long)|uniprotkb:Viable in a HAL3 SIT4 background protein 3(gene name synonym)|uniprotkb:VHS3(gene name)|psi-mi:VHS3(display_short)|uniprotkb:YOR054C(locus name)|uniprotkb:YOR29-05(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21322155|imex:IM-26944-279 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014697.1|sgd:S000005580|dip:DIP-4172N|mint:Q08438|ensemblfungi:YOR054C(gene)|ensemblfungi:YOR054C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0007049"(cell cycle)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0030004"(cellular monovalent inorganic cation homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|ensemblgenomes:YOR054C(identity) refseq:NP_014697.1|sgd:S000005580|dip:DIP-4172N|mint:Q08438|ensemblfungi:YOR054C(gene)|ensemblfungi:YOR054C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0007049"(cell cycle)|go:"GO:0010181"(FMN binding)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0030004"(cellular monovalent inorganic cation homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0071513"(phosphopantothenoylcysteine decarboxylase complex)|go:"GO:1990143"(CoA-synthesizing protein complex)|interpro:IPR003382(Flavoprotein)|interpro:IPR036551|ensemblgenomes:YOR054C(identity) - crc64:A97623473CB6F605 crc64:A97623473CB6F605 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:xBrkL/88mlDFkk10q3ASQnr0rv0559292 rogid:xBrkL/88mlDFkk10q3ASQnr0rv0559292 rigid:ApFfwAFJaoUlk7QCHk+WLk1lgRg false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06689 uniprotkb:Q06689 intact:EBI-38659|uniprotkb:D6VZ50|ensemblfungi:YLR413W intact:EBI-38659|uniprotkb:D6VZ50|ensemblfungi:YLR413W psi-mi:yl413_yeast(display_long)|uniprotkb:YLR413W(locus name) psi-mi:yl413_yeast(display_long)|uniprotkb:YLR413W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21322143|imex:IM-26944-513 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013517.1|sgd:S000004405|mint:Q06689|dip:DIP-5075N|ensemblfungi:YLR413W(gene)|ensemblfungi:YLR413W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0071944"(cell periphery)|interpro:IPR009571(SUR7)|ensemblgenomes:YLR413W(identity) refseq:NP_013517.1|sgd:S000004405|mint:Q06689|dip:DIP-5075N|ensemblfungi:YLR413W(gene)|ensemblfungi:YLR413W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0071944"(cell periphery)|interpro:IPR009571(SUR7)|ensemblgenomes:YLR413W(identity) - crc64:92E23436DC857E95 crc64:92E23436DC857E95 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:AoTGKjLhw0NECrtuftZqLANonds559292 rogid:AoTGKjLhw0NECrtuftZqLANonds559292 rigid:rHKPeKDsjzKmJ/qPr7R5ia97XfU false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P26343 uniprotkb:P26343 intact:EBI-5489|uniprotkb:D6VX97|ensemblfungi:YKR034W intact:EBI-5489|uniprotkb:D6VX97|ensemblfungi:YKR034W psi-mi:dal80_yeast(display_long)|uniprotkb:YKR034W(locus name)|uniprotkb:DAL80(gene name)|psi-mi:DAL80(display_short)|uniprotkb:UGA43(gene name synonym)|uniprotkb:Regulatory protein UGA43(gene name synonym) psi-mi:dal80_yeast(display_long)|uniprotkb:YKR034W(locus name)|uniprotkb:DAL80(gene name)|psi-mi:DAL80(display_short)|uniprotkb:UGA43(gene name synonym)|uniprotkb:Regulatory protein UGA43(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21322131|imex:IM-26944-277 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012959.1|sgd:S000001742|dip:DIP-2094N|ensemblfungi:YKR034W(gene)|ensemblfungi:YKR034W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042128"(nitrate assimilation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0090295"(nitrogen catabolite repression of transcription)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR039355|ensemblgenomes:YKR034W(identity) refseq:NP_012959.1|sgd:S000001742|dip:DIP-2094N|ensemblfungi:YKR034W(gene)|ensemblfungi:YKR034W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042128"(nitrate assimilation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0090295"(nitrogen catabolite repression of transcription)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR039355|ensemblgenomes:YKR034W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:Qfoc7DZ+/Nwthc4Hf93+iwuYgVg559292 rogid:Qfoc7DZ+/Nwthc4Hf93+iwuYgVg559292 rigid:IY2tV9PNTr+IYF/S0X+I3qdTTYw false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36122 uniprotkb:P36122 intact:EBI-26374|uniprotkb:D6VX92|ensemblfungi:YKR027W intact:EBI-26374|uniprotkb:D6VX92|ensemblfungi:YKR027W psi-mi:bch2_yeast(display_long)|uniprotkb:YKR027W(locus name)|uniprotkb:BUD7 and CHS6 homolog 2(gene name synonym)|uniprotkb:BCH2(gene name)|psi-mi:BCH2(display_short)|uniprotkb:FMP50(gene name synonym) psi-mi:bch2_yeast(display_long)|uniprotkb:YKR027W(locus name)|uniprotkb:BUD7 and CHS6 homolog 2(gene name synonym)|uniprotkb:BCH2(gene name)|psi-mi:BCH2(display_short)|uniprotkb:FMP50(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21322119|imex:IM-26944-275 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001735|interpro:IPR015374(Chs5p-Arf1p binding)|interpro:IPR011990(Tetratricopeptide-like helical)|refseq:NP_012952.3|mint:P36122|ensemblfungi:YKR027W(gene)|ensemblfungi:YKR027W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0034044"(exomer complex)|go:"GO:0034221"(fungal-type cell wall chitin biosynthetic process)|ensemblgenomes:YKR027W(identity) sgd:S000001735|interpro:IPR015374(Chs5p-Arf1p binding)|interpro:IPR011990(Tetratricopeptide-like helical)|refseq:NP_012952.3|mint:P36122|ensemblfungi:YKR027W(gene)|ensemblfungi:YKR027W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0034044"(exomer complex)|go:"GO:0034221"(fungal-type cell wall chitin biosynthetic process)|ensemblgenomes:YKR027W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:qslkZkP7uV5VCA3xouTfbs5IW9Q559292 rogid:qslkZkP7uV5VCA3xouTfbs5IW9Q559292 rigid:hJ+VrGEoU3lDk1uFm+nxi8FZUHA false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02208 uniprotkb:Q02208 intact:EBI-27048|uniprotkb:D6VX76|ensemblfungi:YKR010C intact:EBI-27048|uniprotkb:D6VX76|ensemblfungi:YKR010C psi-mi:tof2_yeast(display_long)|uniprotkb:TOF2(gene name)|psi-mi:TOF2(display_short)|uniprotkb:YK109(orf name)|uniprotkb:YKR010C(locus name) psi-mi:tof2_yeast(display_long)|uniprotkb:TOF2(gene name)|psi-mi:TOF2(display_short)|uniprotkb:YK109(orf name)|uniprotkb:YKR010C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21322107|imex:IM-26944-77 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001718|refseq:NP_012935.3|mint:Q02208|dip:DIP-3803N|ensemblfungi:YKR010C(gene)|ensemblfungi:YKR010C_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007000"(nucleolus organization)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0070550"(rDNA condensation)|interpro:IPR018844|interpro:IPR043185|rcsb pdb:5HOI|rcsb pdb:5V3N|ensemblgenomes:YKR010C(identity) sgd:S000001718|refseq:NP_012935.3|mint:Q02208|dip:DIP-3803N|ensemblfungi:YKR010C(gene)|ensemblfungi:YKR010C_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007000"(nucleolus organization)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0070550"(rDNA condensation)|interpro:IPR018844|interpro:IPR043185|rcsb pdb:5HOI|rcsb pdb:5V3N|ensemblgenomes:YKR010C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:JSZUcVEWUE0GXXKxkdC/l5MWeLc559292 rogid:JSZUcVEWUE0GXXKxkdC/l5MWeLc559292 rigid:2bXUUz7tsqdc+1AKcPu21OL3qnM false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36169 uniprotkb:P36169 intact:EBI-26550|uniprotkb:D6VXG1|uniprotkb:Q86ZT0|ensemblfungi:YKR100C intact:EBI-26550|uniprotkb:D6VXG1|uniprotkb:Q86ZT0|ensemblfungi:YKR100C psi-mi:skg1_yeast(display_long)|uniprotkb:YKR099C-A(orf name)|uniprotkb:YKR100C(locus name)|uniprotkb:SKG1(gene name)|psi-mi:SKG1(display_short) psi-mi:skg1_yeast(display_long)|uniprotkb:YKR099C-A(orf name)|uniprotkb:YKR100C(locus name)|uniprotkb:SKG1(gene name)|psi-mi:SKG1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21322095|imex:IM-26944-75 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013026.2|sgd:S000001808|mint:P36169|dip:DIP-4605N|ensemblfungi:YKR100C(gene)|ensemblfungi:YKR100C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0033101"(cellular bud membrane)|ensemblgenomes:YKR100C(identity) refseq:NP_013026.2|sgd:S000001808|mint:P36169|dip:DIP-4605N|ensemblfungi:YKR100C(gene)|ensemblfungi:YKR100C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0005933"(cellular bud)|go:"GO:0005934"(cellular bud tip)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031505"(fungal-type cell wall organization)|go:"GO:0033101"(cellular bud membrane)|ensemblgenomes:YKR100C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:5M0958TOQRgRN0sv3MGTqI/ee2k559292 rogid:5M0958TOQRgRN0sv3MGTqI/ee2k559292 rigid:+uNeHcHlBpv0JC4J9aJKxjDXZvA false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47176 uniprotkb:P47176 intact:EBI-3462|uniprotkb:Q07124|uniprotkb:D6VWW6|ensemblfungi:YJR148W intact:EBI-3462|uniprotkb:Q07124|uniprotkb:D6VWW6|ensemblfungi:YJR148W psi-mi:bca2_yeast(display_long)|uniprotkb:Protein TWT2(gene name synonym)|uniprotkb:BAT2(gene name)|psi-mi:BAT2(display_short)|uniprotkb:TWT2(gene name synonym)|uniprotkb:YJR148W(locus name)|uniprotkb:J2209(orf name) psi-mi:bca2_yeast(display_long)|uniprotkb:Protein TWT2(gene name synonym)|uniprotkb:BAT2(gene name)|psi-mi:BAT2(display_short)|uniprotkb:TWT2(gene name synonym)|uniprotkb:YJR148W(locus name)|uniprotkb:J2209(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21322083|imex:IM-26944-417 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012682.1|sgd:S000003909|dip:DIP-2151N|mint:P47176|ensemblfungi:YJR148W(gene)|ensemblfungi:YJR148W_mRNA(transcript)|go:"GO:0004084"(branched-chain-amino-acid transaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0009082"(branched-chain amino acid biosynthetic process)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0009097"(isoleucine biosynthetic process)|go:"GO:0009098"(leucine biosynthetic process)|go:"GO:0009099"(valine biosynthetic process)|go:"GO:0019509"(L-methionine salvage from methylthioadenosine)|go:"GO:0050048"("L-leucine:2-oxoglutarate aminotransferase activity")|go:"GO:0052654"(L-leucine transaminase activity)|go:"GO:0052655"(L-valine transaminase activity)|go:"GO:0052656"(L-isoleucine transaminase activity)|interpro:IPR001544(Aminotransferase, class IV)|interpro:IPR005786(Branched-chain amino acid aminotransferase II)|interpro:IPR018300|interpro:IPR033939|interpro:IPR036038|interpro:IPR043131|interpro:IPR043132|reactome:R-SCE-70895|ensemblgenomes:YJR148W(identity) refseq:NP_012682.1|sgd:S000003909|dip:DIP-2151N|mint:P47176|ensemblfungi:YJR148W(gene)|ensemblfungi:YJR148W_mRNA(transcript)|go:"GO:0004084"(branched-chain-amino-acid transaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0009082"(branched-chain amino acid biosynthetic process)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0009097"(isoleucine biosynthetic process)|go:"GO:0009098"(leucine biosynthetic process)|go:"GO:0009099"(valine biosynthetic process)|go:"GO:0019509"(L-methionine salvage from methylthioadenosine)|go:"GO:0050048"("L-leucine:2-oxoglutarate aminotransferase activity")|go:"GO:0052654"(L-leucine transaminase activity)|go:"GO:0052655"(L-valine transaminase activity)|go:"GO:0052656"(L-isoleucine transaminase activity)|interpro:IPR001544(Aminotransferase, class IV)|interpro:IPR005786(Branched-chain amino acid aminotransferase II)|interpro:IPR018300|interpro:IPR033939|interpro:IPR036038|interpro:IPR043131|interpro:IPR043132|reactome:R-SCE-70895|ensemblgenomes:YJR148W(identity) - crc64:12B1BF6D58DFDE6B crc64:12B1BF6D58DFDE6B figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:zKtL0F1BqjBw/U21xBGyoWC1Az4559292 rogid:zKtL0F1BqjBw/U21xBGyoWC1Az4559292 rigid:h+lUKjFXsEzody6bmMN+ts9wzPU false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23292 uniprotkb:P23292 intact:EBI-4729|uniprotkb:D6W129|ensemblfungi:YNL154C intact:EBI-4729|uniprotkb:D6W129|ensemblfungi:YNL154C psi-mi:kc12_yeast(display_long)|uniprotkb:YCK2(gene name)|psi-mi:YCK2(display_short)|uniprotkb:CKI1(gene name synonym)|uniprotkb:YNL154C(locus name)|uniprotkb:N1755(orf name) psi-mi:kc12_yeast(display_long)|uniprotkb:YCK2(gene name)|psi-mi:YCK2(display_short)|uniprotkb:CKI1(gene name synonym)|uniprotkb:YNL154C(locus name)|uniprotkb:N1755(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21322071|imex:IM-26944-511 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014245.1|sgd:S000005098|ensemblfungi:YNL154C(gene)|ensemblfungi:YNL154C_mRNA(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|dip:DIP-720N|mint:P23292|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005937"(mating projection)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0009749"(response to glucose)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|ensemblgenomes:YNL154C(identity) refseq:NP_014245.1|sgd:S000005098|ensemblfungi:YNL154C(gene)|ensemblfungi:YNL154C_mRNA(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|dip:DIP-720N|mint:P23292|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005937"(mating projection)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0009749"(response to glucose)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0071944"(cell periphery)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|ensemblgenomes:YNL154C(identity) - crc64:A88D99BC265BF4FA crc64:A88D99BC265BF4FA figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:1nUIikls1l+co991K+hA3Njzmuc559292 rogid:1nUIikls1l+co991K+hA3Njzmuc559292 rigid:rMTEwIgPmeuVjnfPnl1uKa+GBQs false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17898 uniprotkb:P17898 intact:EBI-2050738|uniprotkb:D6W152|ensemblfungi:YNL130C intact:EBI-2050738|uniprotkb:D6W152|ensemblfungi:YNL130C psi-mi:cpt1_yeast(display_long)|uniprotkb:Diacylglycerol cholinephosphotransferase 1(gene name synonym)|uniprotkb:Sn-1,2-diacylglycerol cholinephosphotransferase(gene name synonym)|uniprotkb:N1218(orf name)|uniprotkb:N1867(orf name)|uniprotkb:YNL130C(locus name)|uniprotkb:CPT1(gene name)|psi-mi:CPT1(display_short)|uniprotkb:Aminoalcohol phosphotransferase CPT1(gene name synonym) psi-mi:cpt1_yeast(display_long)|uniprotkb:Diacylglycerol cholinephosphotransferase 1(gene name synonym)|uniprotkb:Sn-1,2-diacylglycerol cholinephosphotransferase(gene name synonym)|uniprotkb:N1218(orf name)|uniprotkb:N1867(orf name)|uniprotkb:YNL130C(locus name)|uniprotkb:CPT1(gene name)|psi-mi:CPT1(display_short)|uniprotkb:Aminoalcohol phosphotransferase CPT1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21322059|imex:IM-26944-73 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005074|refseq:NP_014269.4|dip:DIP-7848N|mint:P17898|ensemblfungi:YNL130C(gene)|ensemblfungi:YNL130C_mRNA(transcript)|go:"GO:0004142"(diacylglycerol cholinephosphotransferase activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006657"(CDP-choline pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014472(Choline/ethanolaminephosphotransferase)|interpro:IPR043130|reactome:R-SCE-1483191|reactome:R-SCE-1483213|ensemblgenomes:YNL130C(identity) sgd:S000005074|refseq:NP_014269.4|dip:DIP-7848N|mint:P17898|ensemblfungi:YNL130C(gene)|ensemblfungi:YNL130C_mRNA(transcript)|go:"GO:0004142"(diacylglycerol cholinephosphotransferase activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006657"(CDP-choline pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000462(CDP-alcohol phosphatidyltransferase)|interpro:IPR014472(Choline/ethanolaminephosphotransferase)|interpro:IPR043130|reactome:R-SCE-1483191|reactome:R-SCE-1483213|ensemblgenomes:YNL130C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:PsU8UELFPsbtbzOS6oBnXJAuk/A559292 rogid:PsU8UELFPsbtbzOS6oBnXJAuk/A559292 rigid:PVITRZUtPzOoP/YVCeldwvBWxoc false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02201 uniprotkb:Q02201 intact:EBI-12636|uniprotkb:D6VXT9|ensemblfungi:YKR003W intact:EBI-12636|uniprotkb:D6VXT9|ensemblfungi:YKR003W psi-mi:osh6_yeast(display_long)|uniprotkb:YK102(orf name)|uniprotkb:YKR003W(locus name)|uniprotkb:OSH6(gene name)|psi-mi:OSH6(display_short) psi-mi:osh6_yeast(display_long)|uniprotkb:YK102(orf name)|uniprotkb:YKR003W(locus name)|uniprotkb:OSH6(gene name)|psi-mi:OSH6(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21322047|imex:IM-26944-71 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0015914"(phospholipid transport)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0120015"(sterol transfer activity)|rcsb pdb:4B2Z|rcsb pdb:4PH7|reactome:R-SCE-1482801|reactome:R-SCE-192105|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|ensemblfungi:YKR003W(gene)|ensemblfungi:YKR003W_mRNA(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|refseq:NP_012928.1|sgd:S000001711|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|mint:Q02201|ensemblgenomes:YKR003W(identity) go:"GO:0006897"(endocytosis)|go:"GO:0008289"(lipid binding)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0015914"(phospholipid transport)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0016125"(sterol metabolic process)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0120015"(sterol transfer activity)|rcsb pdb:4B2Z|rcsb pdb:4PH7|reactome:R-SCE-1482801|reactome:R-SCE-192105|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|ensemblfungi:YKR003W(gene)|ensemblfungi:YKR003W_mRNA(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|refseq:NP_012928.1|sgd:S000001711|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|mint:Q02201|ensemblgenomes:YKR003W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:aOZdSdLn96ns0C9w9E3r62iNyYo559292 rogid:aOZdSdLn96ns0C9w9E3r62iNyYo559292 rigid:xXYG730zV1SimuP37Bimi+7Exmo false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38853 uniprotkb:P38853 intact:EBI-9619|ensemblfungi:YHR158C|uniprotkb:D3DLA7|uniprotkb:E9P8X4 intact:EBI-9619|ensemblfungi:YHR158C|uniprotkb:D3DLA7|uniprotkb:E9P8X4 psi-mi:kel1_yeast(display_long)|uniprotkb:KEL1(gene name)|psi-mi:KEL1(display_short)|uniprotkb:YHR158C(locus name) psi-mi:kel1_yeast(display_long)|uniprotkb:KEL1(gene name)|psi-mi:KEL1(display_short)|uniprotkb:YHR158C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21322035|imex:IM-26944-509 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR158C(gene)|ensemblfungi:YHR158C_mRNA(transcript)|go:"GO:0000755"(cytogamy)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0090337"(regulation of formin-nucleated actin cable assembly)|go:"GO:1990615"(Kelch-containing formin regulatory complex)|interpro:IPR015915(Kelch-type beta propeller)|refseq:NP_012028.1|sgd:S000001201|dip:DIP-1403N|mint:P38853|ensemblgenomes:YHR158C(identity) ensemblfungi:YHR158C(gene)|ensemblfungi:YHR158C_mRNA(transcript)|go:"GO:0000755"(cytogamy)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0005628"(prospore membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0090337"(regulation of formin-nucleated actin cable assembly)|go:"GO:1990615"(Kelch-containing formin regulatory complex)|interpro:IPR015915(Kelch-type beta propeller)|refseq:NP_012028.1|sgd:S000001201|dip:DIP-1403N|mint:P38853|ensemblgenomes:YHR158C(identity) - crc64:43D0FC570F1D5E4D crc64:43D0FC570F1D5E4D figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:pdHtsxpdf1r7G2K9e9EPHajJS3w559292 rogid:pdHtsxpdf1r7G2K9e9EPHajJS3w559292 rigid:cno0WsQ+5PExykGofARd8EfHanw false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06451 uniprotkb:Q06451 intact:EBI-34275|uniprotkb:D6W4F2|ensemblfungi:YPR156C intact:EBI-34275|uniprotkb:D6W4F2|ensemblfungi:YPR156C psi-mi:tpo3_yeast(display_long)|uniprotkb:TPO3(gene name)|psi-mi:TPO3(display_short)|uniprotkb:P9584.7(orf name)|uniprotkb:YPR156C(locus name) psi-mi:tpo3_yeast(display_long)|uniprotkb:TPO3(gene name)|psi-mi:TPO3(display_short)|uniprotkb:P9584.7(orf name)|uniprotkb:YPR156C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21322023|imex:IM-26944-701 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015482.1|sgd:S000006360|mint:Q06451|dip:DIP-3907N|ensemblfungi:YPR156C(gene)|ensemblfungi:YPR156C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259|ensemblgenomes:YPR156C(identity) refseq:NP_015482.1|sgd:S000006360|mint:Q06451|dip:DIP-3907N|ensemblfungi:YPR156C(gene)|ensemblfungi:YPR156C_mRNA(transcript)|go:"GO:0000296"(spermine transport)|go:"GO:0000297"(spermine transmembrane transporter activity)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259|ensemblgenomes:YPR156C(identity) - crc64:D260ED161F800502 crc64:D260ED161F800502 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:oVpx7Bjk/mK2Q7+/j05tX3gHw7k559292 rogid:oVpx7Bjk/mK2Q7+/j05tX3gHw7k559292 rigid:DjyycKELxY+GJJfCwIqEkgemnaw false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06449 uniprotkb:Q06449 intact:EBI-35523|uniprotkb:D6W4F0|ensemblfungi:YPR154W intact:EBI-35523|uniprotkb:D6W4F0|ensemblfungi:YPR154W psi-mi:pin3_yeast(display_long)|uniprotkb:PIN3(gene name)|psi-mi:PIN3(display_short)|uniprotkb:LAS seventeen-binding protein 2(gene name synonym)|uniprotkb:LSB2(gene name synonym)|uniprotkb:YPR154W(locus name) psi-mi:pin3_yeast(display_long)|uniprotkb:PIN3(gene name)|psi-mi:PIN3(display_short)|uniprotkb:LAS seventeen-binding protein 2(gene name synonym)|uniprotkb:LSB2(gene name synonym)|uniprotkb:YPR154W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21322011|imex:IM-26944-69 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015480.1|sgd:S000006358|dip:DIP-6257N|ensemblfungi:YPR154W(gene)|ensemblfungi:YPR154W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|rcsb pdb:1YNZ|rcsb pdb:1ZX6|go:"GO:0030479"(actin cortical patch)|ensemblgenomes:YPR154W(identity) refseq:NP_015480.1|sgd:S000006358|dip:DIP-6257N|ensemblfungi:YPR154W(gene)|ensemblfungi:YPR154W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|rcsb pdb:1YNZ|rcsb pdb:1ZX6|go:"GO:0030479"(actin cortical patch)|ensemblgenomes:YPR154W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:JeNsn3H/VROp194KQLL/o9IhY6Q559292 rogid:JeNsn3H/VROp194KQLL/o9IhY6Q559292 rigid:0g5D++F7Tqq5fhBvPvSJCZroMpE false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53390 uniprotkb:P53390 intact:EBI-10729|uniprotkb:Q6B2F5|ensemblfungi:YPR138C|uniprotkb:D6W4D6 intact:EBI-10729|uniprotkb:Q6B2F5|ensemblfungi:YPR138C|uniprotkb:D6W4D6 psi-mi:mep3_yeast(display_long)|uniprotkb:MEP3(gene name)|psi-mi:MEP3(display_short)|uniprotkb:YPR138C(locus name)|uniprotkb:P9659.14(orf name)|uniprotkb:AMT3(gene name synonym) psi-mi:mep3_yeast(display_long)|uniprotkb:MEP3(gene name)|psi-mi:MEP3(display_short)|uniprotkb:YPR138C(locus name)|uniprotkb:P9659.14(orf name)|uniprotkb:AMT3(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321999|imex:IM-26944-595 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015464.1|sgd:S000006342|ensemblfungi:YPR138C(gene)|ensemblfungi:YPR138C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|mint:P53390|dip:DIP-4909N|ensemblgenomes:YPR138C(identity) refseq:NP_015464.1|sgd:S000006342|ensemblfungi:YPR138C(gene)|ensemblfungi:YPR138C_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015696"|go:"GO:0019740"(nitrogen utilization)|interpro:IPR001905(Ammonium transporter)|interpro:IPR018047|interpro:IPR024041|interpro:IPR029020|mint:P53390|dip:DIP-4909N|ensemblgenomes:YPR138C(identity) - crc64:2309338F36D96258 crc64:2309338F36D96258 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:UajvXf1E8FU957+oquLoPeSfTjk559292 rogid:UajvXf1E8FU957+oquLoPeSfTjk559292 rigid:yvk6abdFLiwkwBay9mVaCn8yo6I false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06144 uniprotkb:Q06144 intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W intact:EBI-34916|uniprotkb:D6VYY8|ensemblfungi:YLR350W psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:orm2_yeast(display_long)|uniprotkb:ORM2(gene name)|psi-mi:ORM2(display_short)|uniprotkb:YLR350W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321987|imex:IM-26944-415 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695|ensemblgenomes:YLR350W(identity) refseq:NP_013454.1|sgd:S000004342|mint:Q06144|dip:DIP-5579N|ensemblfungi:YLR350W(gene)|ensemblfungi:YLR350W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035339"(SPOTS complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0090155"(negative regulation of sphingolipid biosynthetic process)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:1900060"(negative regulation of ceramide biosynthetic process)|interpro:IPR007203(ORMDL)|reactome:R-SCE-6798695|ensemblgenomes:YLR350W(identity) - crc64:2F474503CAB7C195 crc64:2F474503CAB7C195 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 rogid:sY9Jt1Ogpw+lL+9cnBqUeXBiBdE559292 rigid:TrsCOBBW3CWFbdwa/CyW1usBCCU false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06178 uniprotkb:Q06178 intact:EBI-11803|ensemblfungi:YLR328W|uniprotkb:D6VYX0 intact:EBI-11803|ensemblfungi:YLR328W|uniprotkb:D6VYX0 psi-mi:nma1_yeast(display_long)|uniprotkb:NMA1(gene name)|psi-mi:NMA1(display_short)|uniprotkb:"NAD(+) pyrophosphorylase 1"(gene name synonym)|uniprotkb:"NAD(+) diphosphorylase 1"(gene name synonym)|uniprotkb:Nicotinamide-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:Nicotinate-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:L8543.16(orf name)|uniprotkb:YLR328W(locus name) psi-mi:nma1_yeast(display_long)|uniprotkb:NMA1(gene name)|psi-mi:NMA1(display_short)|uniprotkb:"NAD(+) pyrophosphorylase 1"(gene name synonym)|uniprotkb:"NAD(+) diphosphorylase 1"(gene name synonym)|uniprotkb:Nicotinamide-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:Nicotinate-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:L8543.16(orf name)|uniprotkb:YLR328W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321975|imex:IM-26944-699 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR328W(gene)|ensemblfungi:YLR328W_mRNA(transcript)|go:"GO:0000309"(nicotinamide-nucleotide adenylyltransferase activity)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|reactome:R-SCE-196807|refseq:NP_013432.1|sgd:S000004320|dip:DIP-1228N|mint:Q06178|ensemblgenomes:YLR328W(identity) ensemblfungi:YLR328W(gene)|ensemblfungi:YLR328W_mRNA(transcript)|go:"GO:0000309"(nicotinamide-nucleotide adenylyltransferase activity)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|reactome:R-SCE-196807|refseq:NP_013432.1|sgd:S000004320|dip:DIP-1228N|mint:Q06178|ensemblgenomes:YLR328W(identity) - crc64:A176964E56A30DD8 crc64:A176964E56A30DD8 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:VzrKsykGbQsR8Eh7CHCwn/bCID8559292 rogid:VzrKsykGbQsR8Eh7CHCwn/bCID8559292 rigid:RdDYFZS2eAVeBL386r2JiFyAHAg false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q06169 uniprotkb:Q06169 intact:EBI-31008|intact:EBI-937900|uniprotkb:Q66R43|uniprotkb:D6VYW6|ensemblfungi:YLR324W intact:EBI-31008|intact:EBI-937900|uniprotkb:Q66R43|uniprotkb:D6VYW6|ensemblfungi:YLR324W psi-mi:pex30_yeast(display_long)|uniprotkb:PEX30(gene name)|psi-mi:PEX30(display_short)|uniprotkb:Peroxin-30(gene name synonym)|uniprotkb:YLR324W(locus name) psi-mi:pex30_yeast(display_long)|uniprotkb:PEX30(gene name)|psi-mi:PEX30(display_short)|uniprotkb:Peroxin-30(gene name synonym)|uniprotkb:YLR324W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321963|imex:IM-26944-697 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013428.1|sgd:S000004316|dip:DIP-1800N|mint:Q06169|ensemblfungi:YLR324W(gene)|ensemblfungi:YLR324W_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005933"(cellular bud)|go:"GO:0007031"(peroxisome organization)|go:"GO:0032581"(ER-dependent peroxisome organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071944"(cell periphery)|go:"GO:0097749"(membrane tubulation)|go:"GO:1900063"(regulation of peroxisome organization)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR010482(Integral peroxisomal membrane peroxin)|ensemblgenomes:YLR324W(identity) refseq:NP_013428.1|sgd:S000004316|dip:DIP-1800N|mint:Q06169|ensemblfungi:YLR324W(gene)|ensemblfungi:YLR324W_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005933"(cellular bud)|go:"GO:0007031"(peroxisome organization)|go:"GO:0032581"(ER-dependent peroxisome organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071944"(cell periphery)|go:"GO:0097749"(membrane tubulation)|go:"GO:1900063"(regulation of peroxisome organization)|interpro:IPR006614(Dysferlin, C-terminal)|interpro:IPR010482(Integral peroxisomal membrane peroxin)|ensemblgenomes:YLR324W(identity) - crc64:417DBE56B1C8B1D5 crc64:417DBE56B1C8B1D5 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:vkvJ4GqSW60wMG0m3ChlSzwcC3c559292 rogid:vkvJ4GqSW60wMG0m3ChlSzwcC3c559292 rigid:tYceXTS4/Br+Xaa+Ktmtn4Wt2+8 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39935 uniprotkb:P39935 intact:EBI-9002|ensemblfungi:YGR162W|uniprotkb:D6VUU6 intact:EBI-9002|ensemblfungi:YGR162W|uniprotkb:D6VUU6 psi-mi:if4f1_yeast(display_long)|uniprotkb:YGR162W(locus name)|uniprotkb:TIF4631(gene name)|psi-mi:TIF4631(display_short)|uniprotkb:eIF4G1(gene name synonym)|uniprotkb:mRNA cap-binding protein complex subunit p150(gene name synonym) psi-mi:if4f1_yeast(display_long)|uniprotkb:YGR162W(locus name)|uniprotkb:TIF4631(gene name)|psi-mi:TIF4631(display_short)|uniprotkb:eIF4G1(gene name synonym)|uniprotkb:mRNA cap-binding protein complex subunit p150(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321951|imex:IM-26944-273 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGR162W(gene)|ensemblfungi:YGR162W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0034063"(stress granule assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|go:"GO:1902280"(regulation of RNA helicase activity)|rcsb pdb:2VSO|rcsb pdb:2VSX|rcsb pdb:6Z29|reactome:R-SCE-156827|reactome:R-SCE-166208|reactome:R-SCE-429947|reactome:R-SCE-72649|reactome:R-SCE-72662|reactome:R-SCE-72702|reactome:R-SCE-975956|reactome:R-SCE-975957|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022745|interpro:IPR036211|rcsb pdb:1RF8|refseq:NP_011678.3|sgd:S000003394|mint:P39935|dip:DIP-985N|ensemblgenomes:YGR162W(identity) ensemblfungi:YGR162W(gene)|ensemblfungi:YGR162W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0034063"(stress granule assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|go:"GO:1902280"(regulation of RNA helicase activity)|rcsb pdb:2VSO|rcsb pdb:2VSX|rcsb pdb:6Z29|reactome:R-SCE-156827|reactome:R-SCE-166208|reactome:R-SCE-429947|reactome:R-SCE-72649|reactome:R-SCE-72662|reactome:R-SCE-72702|reactome:R-SCE-975956|reactome:R-SCE-975957|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022745|interpro:IPR036211|rcsb pdb:1RF8|refseq:NP_011678.3|sgd:S000003394|mint:P39935|dip:DIP-985N|ensemblgenomes:YGR162W(identity) - crc64:391256802F86118E crc64:391256802F86118E figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:l5wtszbSL7dltfdiDAVe5zYnxVc559292 rogid:l5wtszbSL7dltfdiDAVe5zYnxVc559292 rigid:/h8kN8vba1ZitWY6meJ+U8SmHOM false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P04807 uniprotkb:P04807 intact:EBI-8738|ensemblfungi:YGL253W|uniprotkb:Q05838|uniprotkb:D6VV82 intact:EBI-8738|ensemblfungi:YGL253W|uniprotkb:Q05838|uniprotkb:D6VV82 psi-mi:hxkb_yeast(display_long)|uniprotkb:HKB(gene name synonym)|uniprotkb:NRB486(orf name)|uniprotkb:YGL253W(locus name)|uniprotkb:HXK2(gene name)|psi-mi:HXK2(display_short)|uniprotkb:HEX1(gene name synonym)|uniprotkb:Hexokinase-B(gene name synonym)|uniprotkb:Hexokinase PII(gene name synonym) psi-mi:hxkb_yeast(display_long)|uniprotkb:HKB(gene name synonym)|uniprotkb:NRB486(orf name)|uniprotkb:YGL253W(locus name)|uniprotkb:HXK2(gene name)|psi-mi:HXK2(display_short)|uniprotkb:HEX1(gene name synonym)|uniprotkb:Hexokinase-B(gene name synonym)|uniprotkb:Hexokinase PII(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321939|imex:IM-26944-695 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YGL253W(gene)|ensemblfungi:YGL253W_mRNA(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0004340"(glucokinase activity)|go:"GO:0004396"(hexokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005536"(glucose binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006013"(mannose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008361"(regulation of cell size)|go:"GO:0008865"(fructokinase activity)|go:"GO:0019158"(mannokinase activity)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032445"(fructose import)|go:"GO:0046015"(regulation of transcription by glucose)|go:"GO:0046323"(glucose import)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001312(Hexokinase)|interpro:IPR019807|interpro:IPR022672|interpro:IPR022673|interpro:IPR043129|rcsb pdb:1IG8|rcsb pdb:2YHX|rcsb pdb:5UWT|reactome:R-SCE-170822|reactome:R-SCE-6798695|reactome:R-SCE-70171|refseq:NP_011261.1|sgd:S000003222|mint:P04807|dip:DIP-2380N|ensemblgenomes:YGL253W(identity) ensemblfungi:YGL253W(gene)|ensemblfungi:YGL253W_mRNA(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0004340"(glucokinase activity)|go:"GO:0004396"(hexokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005536"(glucose binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006013"(mannose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008361"(regulation of cell size)|go:"GO:0008865"(fructokinase activity)|go:"GO:0019158"(mannokinase activity)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032445"(fructose import)|go:"GO:0046015"(regulation of transcription by glucose)|go:"GO:0046323"(glucose import)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001312(Hexokinase)|interpro:IPR019807|interpro:IPR022672|interpro:IPR022673|interpro:IPR043129|rcsb pdb:1IG8|rcsb pdb:2YHX|rcsb pdb:5UWT|reactome:R-SCE-170822|reactome:R-SCE-6798695|reactome:R-SCE-70171|refseq:NP_011261.1|sgd:S000003222|mint:P04807|dip:DIP-2380N|ensemblgenomes:YGL253W(identity) - crc64:D55FF3F8992B2FEF crc64:D55FF3F8992B2FEF figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:DGycg0nxbxnH7W3sJoM9k4t3qYc559292 rogid:DGycg0nxbxnH7W3sJoM9k4t3qYc559292 rigid:xBTHjFkxlWa5PZaztPL5KROtRkM false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32793 uniprotkb:P32793 intact:EBI-24460|uniprotkb:D3DKW1|ensemblfungi:YHR016C intact:EBI-24460|uniprotkb:D3DKW1|ensemblfungi:YHR016C psi-mi:ysc84_yeast(display_long)|uniprotkb:YSC84(gene name)|psi-mi:YSC84(display_short)|uniprotkb:LSB4(gene name synonym)|uniprotkb:LAS seventeen-binding protein 4(gene name synonym)|uniprotkb:YHR016C(locus name) psi-mi:ysc84_yeast(display_long)|uniprotkb:YSC84(gene name)|psi-mi:YSC84(display_short)|uniprotkb:LSB4(gene name synonym)|uniprotkb:LAS seventeen-binding protein 4(gene name synonym)|uniprotkb:YHR016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321927|imex:IM-26944-175 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011880.1|sgd:S000001058|dip:DIP-2026N|mint:P32793|ensemblfungi:YHR016C(gene)|ensemblfungi:YHR016C_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization)|interpro:IPR001452(Src homology-3)|interpro:IPR007461(Protein of unknown function DUF500)|interpro:IPR033643|interpro:IPR036028|rcsb pdb:2A08|ensemblgenomes:YHR016C(identity) refseq:NP_011880.1|sgd:S000001058|dip:DIP-2026N|mint:P32793|ensemblfungi:YHR016C(gene)|ensemblfungi:YHR016C_mRNA(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030479"(actin cortical patch)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051666"(actin cortical patch localization)|interpro:IPR001452(Src homology-3)|interpro:IPR007461(Protein of unknown function DUF500)|interpro:IPR033643|interpro:IPR036028|rcsb pdb:2A08|ensemblgenomes:YHR016C(identity) - crc64:DE42E8ECF5B83C92 crc64:DE42E8ECF5B83C92 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:hirm/OlqdPxvJNPbha68BSFIvmQ559292 rogid:hirm/OlqdPxvJNPbha68BSFIvmQ559292 rigid:Fao2OKPhyMDjJPaNoqHHFYUdYkE false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P27472 uniprotkb:P27472 intact:EBI-8036|uniprotkb:D6VYQ5|ensemblfungi:YLR258W intact:EBI-8036|uniprotkb:D6VYQ5|ensemblfungi:YLR258W psi-mi:gys2_yeast(display_long)|uniprotkb:L8479.8(orf name)|uniprotkb:YLR258W(locus name)|uniprotkb:GSY2(gene name)|psi-mi:GSY2(display_short) psi-mi:gys2_yeast(display_long)|uniprotkb:L8479.8(orf name)|uniprotkb:YLR258W(locus name)|uniprotkb:GSY2(gene name)|psi-mi:GSY2(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321915|imex:IM-26944-693 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013359.1|sgd:S000004248|mint:P27472|dip:DIP-1255N|ensemblfungi:YLR258W(gene)|ensemblfungi:YLR258W_mRNA(transcript)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR008631(Glycogen synthase)|rcsb pdb:3NAZ|rcsb pdb:3NB0|rcsb pdb:3NCH|rcsb pdb:3O3C|rcsb pdb:3RSZ|rcsb pdb:3RT1|rcsb pdb:4KQ2|rcsb pdb:4KQM|rcsb pdb:5SUK|rcsb pdb:5SUL|rcsb pdb:5UW0|rcsb pdb:5UW1|rcsb pdb:5UW4|rcsb pdb:5UX7|rcsb pdb:5VNC|rcsb pdb:6U77|reactome:R-SCE-3322077|ensemblgenomes:YLR258W(identity) refseq:NP_013359.1|sgd:S000004248|mint:P27472|dip:DIP-1255N|ensemblfungi:YLR258W(gene)|ensemblfungi:YLR258W_mRNA(transcript)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR008631(Glycogen synthase)|rcsb pdb:3NAZ|rcsb pdb:3NB0|rcsb pdb:3NCH|rcsb pdb:3O3C|rcsb pdb:3RSZ|rcsb pdb:3RT1|rcsb pdb:4KQ2|rcsb pdb:4KQM|rcsb pdb:5SUK|rcsb pdb:5SUL|rcsb pdb:5UW0|rcsb pdb:5UW1|rcsb pdb:5UW4|rcsb pdb:5UX7|rcsb pdb:5VNC|rcsb pdb:6U77|reactome:R-SCE-3322077|ensemblgenomes:YLR258W(identity) - crc64:4670D8328CEDB0D2 crc64:4670D8328CEDB0D2 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:K8l8dzJOtoIWZHpDN8Bq31o6ahA559292 rogid:K8l8dzJOtoIWZHpDN8Bq31o6ahA559292 rigid:a8PFjDEfRyaKhW66BasafN4WDec false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12396 uniprotkb:Q12396 intact:EBI-38641|uniprotkb:D6VY80|ensemblfungi:YLR080W intact:EBI-38641|uniprotkb:D6VY80|ensemblfungi:YLR080W psi-mi:emp46_yeast(display_long)|uniprotkb:46 kDa endomembrane protein(gene name synonym)|uniprotkb:EMP46(gene name)|psi-mi:EMP46(display_short)|uniprotkb:YLR080W(locus name) psi-mi:emp46_yeast(display_long)|uniprotkb:46 kDa endomembrane protein(gene name synonym)|uniprotkb:EMP46(gene name)|psi-mi:EMP46(display_short)|uniprotkb:YLR080W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321903|imex:IM-26944-173 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013181.1|sgd:S000004070|dip:DIP-4209N|ensemblfungi:YLR080W(gene)|ensemblfungi:YLR080W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR016710(L-type lectin, fungi)|interpro:IPR035661|rcsb pdb:2A6V|rcsb pdb:2A6W|rcsb pdb:2A6X|ensemblgenomes:YLR080W(identity) refseq:NP_013181.1|sgd:S000004070|dip:DIP-4209N|ensemblfungi:YLR080W(gene)|ensemblfungi:YLR080W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR016710(L-type lectin, fungi)|interpro:IPR035661|rcsb pdb:2A6V|rcsb pdb:2A6W|rcsb pdb:2A6X|ensemblgenomes:YLR080W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:hCrYOuwXR3XzkMA6UecPqkakMn8559292 rogid:hCrYOuwXR3XzkMA6UecPqkakMn8559292 rigid:uhA4qRWWzOGumLMgb8nqE8ZGrZo false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40510 uniprotkb:P40510 intact:EBI-16821|ensemblfungi:YIL074C|uniprotkb:D6VVL0 intact:EBI-16821|ensemblfungi:YIL074C|uniprotkb:D6VVL0 psi-mi:ser33_yeast(display_long)|uniprotkb:SER33(gene name)|psi-mi:SER33(display_short)|uniprotkb:2-oxoglutarate reductase(gene name synonym)|uniprotkb:YIL074C(locus name) psi-mi:ser33_yeast(display_long)|uniprotkb:SER33(gene name)|psi-mi:SER33(display_short)|uniprotkb:2-oxoglutarate reductase(gene name synonym)|uniprotkb:YIL074C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321891|imex:IM-26944-67 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|refseq:NP_012191.1|sgd:S000001336|ensemblfungi:YIL074C(gene)|ensemblfungi:YIL074C_mRNA(transcript)|go:"GO:0004617"(phosphoglycerate dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0009070"(serine family amino acid biosynthetic process)|go:"GO:0016618"(hydroxypyruvate reductase activity)|go:"GO:0030267"("glyoxylate reductase (NADP+) activity")|go:"GO:0042802"(identical protein binding)|go:"GO:0051287"(NAD binding)|go:"GO:0061759"(alpha-ketoglutarate reductase activity)|interpro:IPR002912(Amino acid-binding ACT)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|dip:DIP-4483N|mint:P40510|ensemblgenomes:YIL074C(identity) interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|refseq:NP_012191.1|sgd:S000001336|ensemblfungi:YIL074C(gene)|ensemblfungi:YIL074C_mRNA(transcript)|go:"GO:0004617"(phosphoglycerate dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0009070"(serine family amino acid biosynthetic process)|go:"GO:0016618"(hydroxypyruvate reductase activity)|go:"GO:0030267"("glyoxylate reductase (NADP+) activity")|go:"GO:0042802"(identical protein binding)|go:"GO:0051287"(NAD binding)|go:"GO:0061759"(alpha-ketoglutarate reductase activity)|interpro:IPR002912(Amino acid-binding ACT)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|dip:DIP-4483N|mint:P40510|ensemblgenomes:YIL074C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:EL+xZKwWXRcTkChe3CLKM+/WIzI559292 rogid:EL+xZKwWXRcTkChe3CLKM+/WIzI559292 rigid:72M+ecLJxpmZXNzDDyC9Vnl61kc false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P40185 uniprotkb:P40185 intact:EBI-11022|ensemblfungi:YIL051C|uniprotkb:D6VVN0 intact:EBI-11022|ensemblfungi:YIL051C|uniprotkb:D6VVN0 psi-mi:mmf1_yeast(display_long)|uniprotkb:MMF1(gene name)|psi-mi:MMF1(display_short)|uniprotkb:IBM1(gene name synonym)|uniprotkb:Maintenance of mitochondrial function 1(gene name synonym)|uniprotkb:Isoleucine biosynthesis and maintenance of intact mitochondria 1(gene name synonym)|uniprotkb:YIL051C(locus name) psi-mi:mmf1_yeast(display_long)|uniprotkb:MMF1(gene name)|psi-mi:MMF1(display_short)|uniprotkb:IBM1(gene name synonym)|uniprotkb:Maintenance of mitochondrial function 1(gene name synonym)|uniprotkb:Isoleucine biosynthesis and maintenance of intact mitochondria 1(gene name synonym)|uniprotkb:YIL051C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321879|imex:IM-26944-691 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YIL051C(gene)|ensemblfungi:YIL051C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0009097"(isoleucine biosynthetic process)|go:"GO:0019239"(deaminase activity)|go:"GO:0032543"(mitochondrial translation)|go:"GO:1901565"(organonitrogen compound catabolic process)|interpro:IPR006056(YjgF-like protein)|interpro:IPR006175(Endoribonuclease L-PSP)|interpro:IPR019897|interpro:IPR035959|rcsb pdb:3QUW|refseq:NP_012213.3|sgd:S000001313|mint:P40185|dip:DIP-4714N|ensemblgenomes:YIL051C(identity) ensemblfungi:YIL051C(gene)|ensemblfungi:YIL051C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0009097"(isoleucine biosynthetic process)|go:"GO:0019239"(deaminase activity)|go:"GO:0032543"(mitochondrial translation)|go:"GO:1901565"(organonitrogen compound catabolic process)|interpro:IPR006056(YjgF-like protein)|interpro:IPR006175(Endoribonuclease L-PSP)|interpro:IPR019897|interpro:IPR035959|rcsb pdb:3QUW|refseq:NP_012213.3|sgd:S000001313|mint:P40185|dip:DIP-4714N|ensemblgenomes:YIL051C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:N825kjK9jblhOOg4MZP7RmQXN1M559292 rogid:N825kjK9jblhOOg4MZP7RmQXN1M559292 rigid:ie4e509NWwQCuifdFfbaHy8M5wY false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P21373 uniprotkb:P21373 intact:EBI-20174|uniprotkb:Q54AD8|uniprotkb:D6VWM0|uniprotkb:E9P8Y8|ensemblfungi:YJR049C intact:EBI-20174|uniprotkb:Q54AD8|uniprotkb:D6VWM0|uniprotkb:E9P8Y8|ensemblfungi:YJR049C psi-mi:utr1_yeast(display_long)|uniprotkb:UTR1(gene name)|psi-mi:UTR1(display_short)|uniprotkb:YJR049C(locus name)|uniprotkb:J1655(orf name)|uniprotkb:Unknown transcript 1 protein(gene name synonym) psi-mi:utr1_yeast(display_long)|uniprotkb:UTR1(gene name)|psi-mi:UTR1(display_short)|uniprotkb:YJR049C(locus name)|uniprotkb:J1655(orf name)|uniprotkb:Unknown transcript 1 protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321867|imex:IM-26944-65 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012583.1|sgd:S000003810|ensemblfungi:YJR049C(gene)|ensemblfungi:YJR049C_mRNA(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0042736"(NADH kinase activity)|interpro:IPR002504(ATP-NAD/AcoX kinase)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017437(ATP-NAD kinase, PpnK-type, all-beta)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|reactome:R-SCE-196807|mint:P21373|dip:DIP-4479N|ensemblgenomes:YJR049C(identity) refseq:NP_012583.1|sgd:S000003810|ensemblfungi:YJR049C(gene)|ensemblfungi:YJR049C_mRNA(transcript)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0042736"(NADH kinase activity)|interpro:IPR002504(ATP-NAD/AcoX kinase)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017437(ATP-NAD kinase, PpnK-type, all-beta)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|reactome:R-SCE-196807|mint:P21373|dip:DIP-4479N|ensemblgenomes:YJR049C(identity) - crc64:1BF4F01D7213B94B crc64:1BF4F01D7213B94B figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:l/mDQcBTaLoGMxT50H2W7npbw2g559292 rogid:l/mDQcBTaLoGMxT50H2W7npbw2g559292 rigid:4aUzAkgv5c5PxpRaVpcCSEd5DXc false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10659 uniprotkb:P10659 intact:EBI-10789|ensemblfungi:YLR180W|uniprotkb:D6VYI4 intact:EBI-10789|ensemblfungi:YLR180W|uniprotkb:D6VYI4 psi-mi:metk1_yeast(display_long)|uniprotkb:SAM1(gene name)|psi-mi:SAM1(display_short)|uniprotkb:ETH10(gene name synonym)|uniprotkb:YLR180W(locus name)|uniprotkb:L9470.9(orf name)|uniprotkb:Methionine adenosyltransferase 1(gene name synonym) psi-mi:metk1_yeast(display_long)|uniprotkb:SAM1(gene name)|psi-mi:SAM1(display_short)|uniprotkb:ETH10(gene name synonym)|uniprotkb:YLR180W(locus name)|uniprotkb:L9470.9(orf name)|uniprotkb:Methionine adenosyltransferase 1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321855|imex:IM-26944-413 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YLR180W(gene)|ensemblfungi:YLR180W_mRNA(transcript)|go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006555"(methionine metabolic process)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0046872"(metal ion binding)|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022628|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636|reactome:R-SCE-156581|reactome:R-SCE-1614635|reactome:R-SCE-2408508|refseq:NP_013281.1|sgd:S000004170|mint:P10659|dip:DIP-6667N|ensemblgenomes:YLR180W(identity) ensemblfungi:YLR180W(gene)|ensemblfungi:YLR180W_mRNA(transcript)|go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006555"(methionine metabolic process)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0046872"(metal ion binding)|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022628|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636|reactome:R-SCE-156581|reactome:R-SCE-1614635|reactome:R-SCE-2408508|refseq:NP_013281.1|sgd:S000004170|mint:P10659|dip:DIP-6667N|ensemblgenomes:YLR180W(identity) - crc64:18F82FC809EE4706 crc64:18F82FC809EE4706 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:PmIeDsMIksGSxihwmK1DqLFOItc559292 rogid:PmIeDsMIksGSxihwmK1DqLFOItc559292 rigid:oZO3+/xQq7efOmrkfBUmHetfoaI false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12236 uniprotkb:Q12236 intact:EBI-9844|intact:EBI-2935811|uniprotkb:D6W1W8|ensemblfungi:YOL100W intact:EBI-9844|intact:EBI-2935811|uniprotkb:D6W1W8|ensemblfungi:YOL100W psi-mi:pkh2_yeast(display_long)|uniprotkb:YOL100W(locus name)|uniprotkb:HRC1081(orf name)|uniprotkb:PKH2(gene name)|psi-mi:PKH2(display_short)|uniprotkb:PKB-activating kinase homolog 2(gene name synonym) psi-mi:pkh2_yeast(display_long)|uniprotkb:YOL100W(locus name)|uniprotkb:HRC1081(orf name)|uniprotkb:PKH2(gene name)|psi-mi:PKH2(display_short)|uniprotkb:PKB-activating kinase homolog 2(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321843|imex:IM-26944-355 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014541.1|sgd:S000005460|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0060211"("regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|ensemblfungi:YOL100W(gene)|ensemblfungi:YOL100W_mRNA(transcript)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039046|reactome:R-SCE-114604|reactome:R-SCE-1257604|reactome:R-SCE-165158|reactome:R-SCE-202424|reactome:R-SCE-2730905|reactome:R-SCE-389357|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0004672"(protein kinase activity)|reactome:R-SCE-392451|reactome:R-SCE-5218920|reactome:R-SCE-5218921|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-6804757|reactome:R-SCE-9634635|reactome:R-SCE-5625740|dip:DIP-6295N|mint:Q12236|ensemblgenomes:YOL100W(identity) refseq:NP_014541.1|sgd:S000005460|go:"GO:0005634"(nucleus)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0060211"("regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|ensemblfungi:YOL100W(gene)|ensemblfungi:YOL100W_mRNA(transcript)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039046|reactome:R-SCE-114604|reactome:R-SCE-1257604|reactome:R-SCE-165158|reactome:R-SCE-202424|reactome:R-SCE-2730905|reactome:R-SCE-389357|go:"GO:0000196"(cell wall integrity MAPK cascade)|go:"GO:0004672"(protein kinase activity)|reactome:R-SCE-392451|reactome:R-SCE-5218920|reactome:R-SCE-5218921|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-6804757|reactome:R-SCE-9634635|reactome:R-SCE-5625740|dip:DIP-6295N|mint:Q12236|ensemblgenomes:YOL100W(identity) - crc64:BE0DD9D49AC2EBC3 crc64:BE0DD9D49AC2EBC3 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:KzJ+WGY+PylRDsK1olfak8IyuXM559292 rogid:KzJ+WGY+PylRDsK1olfak8IyuXM559292 rigid:ed169Tf6LtB2nLKWzbLxDRQdPiY false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P26570 uniprotkb:P26570 intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 intact:EBI-13807|uniprotkb:Q00979|ensemblfungi:YML016C|uniprotkb:D6VZF8 psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:ppz1_yeast(display_long)|uniprotkb:PPZ1(gene name)|psi-mi:PPZ1(display_short)|uniprotkb:YM9571.02C(orf name)|uniprotkb:YML016C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321831|imex:IM-26944-411 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N|ensemblgenomes:YML016C(identity) ensemblfungi:YML016C(gene)|ensemblfungi:YML016C_mRNA(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011159(Phosphoprotein phosphatase PPZ)|interpro:IPR029052|interpro:IPR031675|refseq:NP_013696.1|sgd:S000004478|mint:P26570|dip:DIP-557N|ensemblgenomes:YML016C(identity) - crc64:8B7F009521F72C15 crc64:8B7F009521F72C15 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 rogid:aybUrPA5WH/mgdDx6VD8N4F/4x0559292 rigid:XPqOhD1g2KNXgCNytyn/tgUSAAo false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33302 uniprotkb:P33302 intact:EBI-13038|uniprotkb:D6W2L0|ensemblfungi:YOR153W intact:EBI-13038|uniprotkb:D6W2L0|ensemblfungi:YOR153W psi-mi:pdr5_yeast(display_long)|uniprotkb:PDR5(gene name)|psi-mi:PDR5(display_short)|uniprotkb:LEM1(gene name synonym)|uniprotkb:STS1(gene name synonym)|uniprotkb:YDR1(gene name synonym)|uniprotkb:Pleiotropic drug resistance protein 5(gene name synonym)|uniprotkb:Suppressor of toxicity of sporidesmin(gene name synonym)|uniprotkb:YOR153W(locus name) psi-mi:pdr5_yeast(display_long)|uniprotkb:PDR5(gene name)|psi-mi:PDR5(display_short)|uniprotkb:LEM1(gene name synonym)|uniprotkb:STS1(gene name synonym)|uniprotkb:YDR1(gene name synonym)|uniprotkb:Pleiotropic drug resistance protein 5(gene name synonym)|uniprotkb:Suppressor of toxicity of sporidesmin(gene name synonym)|uniprotkb:YOR153W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321819|imex:IM-26944-353 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005679|refseq:NP_014796.3|mint:P33302|dip:DIP-6776N|ensemblfungi:YOR153W(gene)|ensemblfungi:YOR153W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR027417|interpro:IPR029481|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblgenomes:YOR153W(identity) sgd:S000005679|refseq:NP_014796.3|mint:P33302|dip:DIP-6776N|ensemblfungi:YOR153W(gene)|ensemblfungi:YOR153W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030003"(cellular cation homeostasis)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0071944"(cell periphery)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR005285(Pleiotropic drug resistance protein PDR)|interpro:IPR010929(CDR ABC transporter)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR017871|interpro:IPR027417|interpro:IPR029481|interpro:IPR034001|interpro:IPR034003|interpro:IPR043926|ensemblgenomes:YOR153W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:Sd6SJWf6B0rDZnLVaPHyvr4lhew559292 rogid:Sd6SJWf6B0rDZnLVaPHyvr4lhew559292 rigid:/DKZcT9cYe8Q0eQgKjY6fU9ZGb4 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32324 uniprotkb:P32324 intact:EBI-6333|uniprotkb:Q6JEF7|uniprotkb:D6VT19|ensemblfungi:YDR385W|ensemblfungi:YOR133W intact:EBI-6333|uniprotkb:Q6JEF7|uniprotkb:D6VT19|ensemblfungi:YDR385W|ensemblfungi:YOR133W psi-mi:ef2_yeast(display_long)|uniprotkb:EFT1(gene name)|psi-mi:EFT1(display_short)|uniprotkb:YOR133W(locus name)|uniprotkb:O3317(orf name)|uniprotkb:YOR3317W(orf name)|uniprotkb:EFT2(gene name)|psi-mi:EFT2(display_short)|uniprotkb:YDR385W(locus name)|uniprotkb:Translation elongation factor 2(gene name synonym)|uniprotkb:Eukaryotic elongation factor 2(gene name synonym)|uniprotkb:Ribosomal translocase(gene name synonym) psi-mi:ef2_yeast(display_long)|uniprotkb:EFT1(gene name)|psi-mi:EFT1(display_short)|uniprotkb:YOR133W(locus name)|uniprotkb:O3317(orf name)|uniprotkb:YOR3317W(orf name)|uniprotkb:EFT2(gene name)|psi-mi:EFT2(display_short)|uniprotkb:YDR385W(locus name)|uniprotkb:Translation elongation factor 2(gene name synonym)|uniprotkb:Eukaryotic elongation factor 2(gene name synonym)|uniprotkb:Ribosomal translocase(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321807|imex:IM-26944-171 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010673.1|refseq:NP_014776.1|sgd:S000005659|sgd:S000002793|ensemblfungi:YDR385W(gene)|ensemblfungi:YDR385W_mRNA(transcript)|ensemblfungi:YOR133W(gene)|ensemblfungi:YOR133W_mRNA(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0019843"(rRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0051087"(chaperone binding)|go:"GO:1990145"(maintenance of translational fidelity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|mint:P32324|dip:DIP-4911N|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|rcsb pdb:1N0U|rcsb pdb:1N0V|rcsb pdb:1U2R|rcsb pdb:1ZM2|rcsb pdb:1ZM3|rcsb pdb:1ZM4|rcsb pdb:1ZM9|rcsb pdb:2E1R|rcsb pdb:2NPF|rcsb pdb:2P8W|rcsb pdb:2P8X|rcsb pdb:2P8Y|rcsb pdb:2P8Z|rcsb pdb:2ZIT|rcsb pdb:3B78|rcsb pdb:3B82|rcsb pdb:3B8H|rcsb pdb:3DNY|rcsb pdb:4V4B|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|reactome:R-SCE-156902|reactome:R-SCE-5358493|reactome:R-SCE-6798695|ensemblgenomes:YOR133W(identity) refseq:NP_010673.1|refseq:NP_014776.1|sgd:S000005659|sgd:S000002793|ensemblfungi:YDR385W(gene)|ensemblfungi:YDR385W_mRNA(transcript)|ensemblfungi:YOR133W(gene)|ensemblfungi:YOR133W_mRNA(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0019843"(rRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0051087"(chaperone binding)|go:"GO:1990145"(maintenance of translational fidelity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|mint:P32324|dip:DIP-4911N|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|rcsb pdb:1N0U|rcsb pdb:1N0V|rcsb pdb:1U2R|rcsb pdb:1ZM2|rcsb pdb:1ZM3|rcsb pdb:1ZM4|rcsb pdb:1ZM9|rcsb pdb:2E1R|rcsb pdb:2NPF|rcsb pdb:2P8W|rcsb pdb:2P8X|rcsb pdb:2P8Y|rcsb pdb:2P8Z|rcsb pdb:2ZIT|rcsb pdb:3B78|rcsb pdb:3B82|rcsb pdb:3B8H|rcsb pdb:3DNY|rcsb pdb:4V4B|rcsb pdb:5JUO|rcsb pdb:5JUP|rcsb pdb:5JUS|rcsb pdb:5JUT|rcsb pdb:5JUU|rcsb pdb:6GQ1|rcsb pdb:6GQB|rcsb pdb:6GQV|reactome:R-SCE-156902|reactome:R-SCE-5358493|reactome:R-SCE-6798695|ensemblgenomes:YOR133W(identity) - crc64:FD2F8073CB9B66AA crc64:FD2F8073CB9B66AA figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:mlyt9YKZrGhGbsSlvxNJ0p1C67I559292 rogid:mlyt9YKZrGhGbsSlvxNJ0p1C67I559292 rigid:jWPbFhrzSUX8llcuPU1CyVbbIq4 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39083 uniprotkb:P39083 intact:EBI-15044|uniprotkb:P39934|uniprotkb:D6W2I5|ensemblfungi:YOR127W intact:EBI-15044|uniprotkb:P39934|uniprotkb:D6W2I5|ensemblfungi:YOR127W psi-mi:rga1_yeast(display_long)|uniprotkb:RGA1(gene name)|psi-mi:RGA1(display_short)|uniprotkb:DBM1(gene name synonym)|uniprotkb:THE1(gene name synonym)|uniprotkb:YOR127W(locus name)|uniprotkb:O3290(orf name)|uniprotkb:YOR3290W(orf name) psi-mi:rga1_yeast(display_long)|uniprotkb:RGA1(gene name)|psi-mi:RGA1(display_short)|uniprotkb:DBM1(gene name synonym)|uniprotkb:THE1(gene name synonym)|uniprotkb:YOR127W(locus name)|uniprotkb:O3290(orf name)|uniprotkb:YOR3290W(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321795|imex:IM-26944-339 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014770.1|sgd:S000005653|ensemblfungi:YOR127W(gene)|ensemblfungi:YOR127W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005621"(cellular bud scar)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007015"(actin filament organization)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0007119"(budding cell isotropic bud growth)|go:"GO:0007120"(axial cellular bud site selection)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031106"(septin ring organization)|go:"GO:0032177"(cellular bud neck split septin rings)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0071597"(cellular birth scar)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000198(RhoGAP)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-SCE-6798695|reactome:R-SCE-8980692|reactome:R-SCE-9013148|reactome:R-SCE-9013405|reactome:R-SCE-9013423|reactome:R-SCE-9035034|dip:DIP-1559N|mint:P39083|ensemblgenomes:YOR127W(identity) refseq:NP_014770.1|sgd:S000005653|ensemblfungi:YOR127W(gene)|ensemblfungi:YOR127W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005621"(cellular bud scar)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007015"(actin filament organization)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0007119"(budding cell isotropic bud growth)|go:"GO:0007120"(axial cellular bud site selection)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031106"(septin ring organization)|go:"GO:0032177"(cellular bud neck split septin rings)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0071597"(cellular birth scar)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000198(RhoGAP)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-SCE-6798695|reactome:R-SCE-8980692|reactome:R-SCE-9013148|reactome:R-SCE-9013405|reactome:R-SCE-9013423|reactome:R-SCE-9035034|dip:DIP-1559N|mint:P39083|ensemblgenomes:YOR127W(identity) - crc64:C805411B57553791 crc64:C805411B57553791 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:xdYXgZQ0mCidt7tTuMXDCcBQIxc559292 rogid:xdYXgZQ0mCidt7tTuMXDCcBQIxc559292 rigid:pH8yBSog8nv13sLUAsRwn65PHqM false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38695 uniprotkb:P38695 intact:EBI-8778|ensemblfungi:YHR096C|uniprotkb:D3DL46 intact:EBI-8778|ensemblfungi:YHR096C|uniprotkb:D3DL46 psi-mi:hxt5_yeast(display_long)|uniprotkb:YHR096C(locus name)|uniprotkb:HXT5(gene name)|psi-mi:HXT5(display_short) psi-mi:hxt5_yeast(display_long)|uniprotkb:YHR096C(locus name)|uniprotkb:HXT5(gene name)|psi-mi:HXT5(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321783|imex:IM-26944-271 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YHR096C(gene)|ensemblfungi:YHR096C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011964.1|sgd:S000001138|mint:P38695|dip:DIP-5594N|ensemblgenomes:YHR096C(identity) ensemblfungi:YHR096C(gene)|ensemblfungi:YHR096C_mRNA(transcript)|go:"GO:0005351"("carbohydrate:proton symporter activity")|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005353"(fructose transmembrane transporter activity)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0008645"(hexose transmembrane transport)|go:"GO:0015578"(mannose transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0071944"(cell periphery)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|refseq:NP_011964.1|sgd:S000001138|mint:P38695|dip:DIP-5594N|ensemblgenomes:YHR096C(identity) - crc64:6906721BAC1A5F87 crc64:6906721BAC1A5F87 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:aZGrWmUu+AZ4G6qmTG+Z+p6i7hs559292 rogid:aZGrWmUu+AZ4G6qmTG+Z+p6i7hs559292 rigid:1CkdsQ+dbgqhq7BwyzIeKNP8dJk false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08412 uniprotkb:Q08412 intact:EBI-37580|uniprotkb:D6W2A8|ensemblfungi:YOR042W intact:EBI-37580|uniprotkb:D6W2A8|ensemblfungi:YOR042W psi-mi:cue5_yeast(display_long)|uniprotkb:YOR042W(locus name)|uniprotkb:CUE5(gene name)|psi-mi:CUE5(display_short)|uniprotkb:Coupling of ubiquitin conjugation to ER degradation protein 5(gene name synonym) psi-mi:cue5_yeast(display_long)|uniprotkb:YOR042W(locus name)|uniprotkb:CUE5(gene name)|psi-mi:CUE5(display_short)|uniprotkb:Coupling of ubiquitin conjugation to ER degradation protein 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321771|imex:IM-26944-409 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014685.1|sgd:S000005568|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|mint:Q08412|interpro:IPR041807|ensemblfungi:YOR042W(gene)|ensemblfungi:YOR042W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0043130"(ubiquitin binding)|reactome:R-SCE-6798695|ensemblgenomes:YOR042W(identity) refseq:NP_014685.1|sgd:S000005568|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR009060(UBA-like)|mint:Q08412|interpro:IPR041807|ensemblfungi:YOR042W(gene)|ensemblfungi:YOR042W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0043130"(ubiquitin binding)|reactome:R-SCE-6798695|ensemblgenomes:YOR042W(identity) - crc64:0D455F9AD637AC8D crc64:0D455F9AD637AC8D figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:bUu2kNMFibdM8RUj460pMdBr2UA559292 rogid:bUu2kNMFibdM8RUj460pMdBr2UA559292 rigid:9n+exKNkVakhFqcXHdM54Jh9dPc false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P29311 uniprotkb:P29311 intact:EBI-3661|uniprotkb:Q06854|uniprotkb:D3DM86|ensemblfungi:YER177W intact:EBI-3661|uniprotkb:Q06854|uniprotkb:D3DM86|ensemblfungi:YER177W psi-mi:bmh1_yeast(display_long)|uniprotkb:YER177W(locus name)|uniprotkb:BMH1(gene name)|psi-mi:BMH1(display_short) psi-mi:bmh1_yeast(display_long)|uniprotkb:YER177W(locus name)|uniprotkb:BMH1(gene name)|psi-mi:BMH1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321759|imex:IM-26944-169 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000979|refseq:NP_011104.3|dip:DIP-4313N|mint:P29311|ensemblfungi:YER177W(gene)|ensemblfungi:YER177W_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030437"(ascospore formation)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0034221"(fungal-type cell wall chitin biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070842"(aggresome assembly)|go:"GO:0070873"(regulation of glycogen metabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:5N6N|rcsb pdb:6QK8|ensemblgenomes:YER177W(identity) sgd:S000000979|refseq:NP_011104.3|dip:DIP-4313N|mint:P29311|ensemblfungi:YER177W(gene)|ensemblfungi:YER177W_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001402"(signal transduction involved in filamentous growth)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030437"(ascospore formation)|go:"GO:0031578"(mitotic spindle orientation checkpoint signaling)|go:"GO:0034221"(fungal-type cell wall chitin biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070842"(aggresome assembly)|go:"GO:0070873"(regulation of glycogen metabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:5N6N|rcsb pdb:6QK8|ensemblgenomes:YER177W(identity) - crc64:0A234167E313688B crc64:0A234167E313688B figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:RnX8tqsjlxM+7Mi+Thlhc1XrTy4559292 rogid:RnX8tqsjlxM+7Mi+Thlhc1XrTy4559292 rigid:KbpNa0PMfV2iTUD55uDtG2ra5qo false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32660 uniprotkb:P32660 intact:EBI-3121|uniprotkb:D3DM74|ensemblfungi:YER166W intact:EBI-3121|uniprotkb:D3DM74|ensemblfungi:YER166W psi-mi:atc5_yeast(display_long)|uniprotkb:DNF1(gene name)|psi-mi:DNF1(display_short)|uniprotkb:YER166W(locus name)|uniprotkb:SYGP-ORF7(orf name)|uniprotkb:Flippase DNF1(gene name synonym) psi-mi:atc5_yeast(display_long)|uniprotkb:DNF1(gene name)|psi-mi:DNF1(display_short)|uniprotkb:YER166W(locus name)|uniprotkb:SYGP-ORF7(orf name)|uniprotkb:Flippase DNF1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321747|imex:IM-26944-63 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000968|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR026871|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:7KY6|rcsb pdb:7KYB|rcsb pdb:7KYC|refseq:NP_011093.3|dip:DIP-7949N|mint:P32660|ensemblfungi:YER166W(gene)|ensemblfungi:YER166W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|ensemblgenomes:YER166W(identity) sgd:S000000968|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR026871|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:7KY6|rcsb pdb:7KYB|rcsb pdb:7KYC|refseq:NP_011093.3|dip:DIP-7949N|mint:P32660|ensemblfungi:YER166W(gene)|ensemblfungi:YER166W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|ensemblgenomes:YER166W(identity) - crc64:3CC3FBA8ADDE8960 crc64:3CC3FBA8ADDE8960 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:4ciEaV0aGjDqtpexkFJ0l737SpA559292 rogid:4ciEaV0aGjDqtpexkFJ0l737SpA559292 rigid:fZ/KnLPKO/KfwbZaF2tBUbEUOV0 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53865 uniprotkb:P53865 intact:EBI-29172|uniprotkb:D6W0W5|ensemblfungi:YNL225C intact:EBI-29172|uniprotkb:D6W0W5|ensemblfungi:YNL225C psi-mi:cnm67_yeast(display_long)|uniprotkb:CNM67(gene name)|psi-mi:CNM67(display_short)|uniprotkb:N1264(orf name)|uniprotkb:YNL225C(locus name) psi-mi:cnm67_yeast(display_long)|uniprotkb:CNM67(gene name)|psi-mi:CNM67(display_short)|uniprotkb:N1264(orf name)|uniprotkb:YNL225C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21321735|imex:IM-26944-269 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014174.1|sgd:S000005169|dip:DIP-2447N|ensemblfungi:YNL225C(gene)|ensemblfungi:YNL225C_mRNA(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005824"(outer plaque of spindle pole body)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0051300"(spindle pole body organization)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0061499"(outer plaque of mitotic spindle pole body)|interpro:IPR021750|rcsb pdb:3OA7|ensemblgenomes:YNL225C(identity) refseq:NP_014174.1|sgd:S000005169|dip:DIP-2447N|ensemblfungi:YNL225C(gene)|ensemblfungi:YNL225C_mRNA(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005824"(outer plaque of spindle pole body)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0051300"(spindle pole body organization)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0061499"(outer plaque of mitotic spindle pole body)|interpro:IPR021750|rcsb pdb:3OA7|ensemblgenomes:YNL225C(identity) - crc64:C4DE7631A70E695A crc64:C4DE7631A70E695A figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:CZcSz7xsDbbKLkvMf5Cw3zA+6og559292 rogid:CZcSz7xsDbbKLkvMf5Cw3zA+6og559292 rigid:YGvx25gnx1UQBcBPbAdP07AYyKA false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12043 uniprotkb:Q12043 intact:EBI-34845|uniprotkb:Q7LH13|uniprotkb:D6W2E4|ensemblfungi:YOR081C intact:EBI-34845|uniprotkb:Q7LH13|uniprotkb:D6W2E4|ensemblfungi:YOR081C psi-mi:tgl5_yeast(display_long)|uniprotkb:TGL5(gene name)|psi-mi:TGL5(display_short)|uniprotkb:STC2(gene name synonym)|uniprotkb:YOR29-32(orf name)|uniprotkb:YOR2964C(orf name)|uniprotkb:YOR081C(locus name)|uniprotkb:Lipase 5(gene name synonym) psi-mi:tgl5_yeast(display_long)|uniprotkb:TGL5(gene name)|psi-mi:TGL5(display_short)|uniprotkb:STC2(gene name synonym)|uniprotkb:YOR29-32(orf name)|uniprotkb:YOR2964C(orf name)|uniprotkb:YOR081C(locus name)|uniprotkb:Lipase 5(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21322167|imex:IM-26944-515 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014724.1|sgd:S000005607|mint:Q12043|dip:DIP-6280N|ensemblfungi:YOR081C(gene)|ensemblfungi:YOR081C_mRNA(transcript)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042171"(lysophosphatidic acid acyltransferase activity)|interpro:IPR002641(Patatin)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR021771|ensemblgenomes:YOR081C(identity) refseq:NP_014724.1|sgd:S000005607|mint:Q12043|dip:DIP-6280N|ensemblfungi:YOR081C(gene)|ensemblfungi:YOR081C_mRNA(transcript)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042171"(lysophosphatidic acid acyltransferase activity)|interpro:IPR002641(Patatin)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR021771|ensemblgenomes:YOR081C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:ccHxygbWfyyQXKaSbOL4iYhikms559292 rogid:ccHxygbWfyyQXKaSbOL4iYhikms559292 rigid:ZsEFG3ruDf26aKARIiV2gHBhu/A false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36017 uniprotkb:P36017 intact:EBI-29399|uniprotkb:D6W2F0|ensemblfungi:YOR089C intact:EBI-29399|uniprotkb:D6W2F0|ensemblfungi:YOR089C psi-mi:vps21_yeast(display_long)|uniprotkb:GTP-binding protein YPT51(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 12(gene name synonym)|uniprotkb:VPS21(gene name)|psi-mi:VPS21(display_short)|uniprotkb:YOR089C(locus name)|uniprotkb:YOR3154C(orf name)|uniprotkb:VPS12(gene name synonym)|uniprotkb:VPT12(gene name synonym)|uniprotkb:YPT21(gene name synonym)|uniprotkb:YPT51(gene name synonym) psi-mi:vps21_yeast(display_long)|uniprotkb:GTP-binding protein YPT51(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 12(gene name synonym)|uniprotkb:VPS21(gene name)|psi-mi:VPS21(display_short)|uniprotkb:YOR089C(locus name)|uniprotkb:YOR3154C(orf name)|uniprotkb:VPS12(gene name synonym)|uniprotkb:VPT12(gene name synonym)|uniprotkb:YPT21(gene name synonym)|uniprotkb:YPT51(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21322299|imex:IM-26944-179 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014732.1|sgd:S000005615|dip:DIP-3801N|mint:P36017|ensemblfungi:YOR089C(gene)|ensemblfungi:YOR089C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0061709"(reticulophagy)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:1EK0|ensemblgenomes:YOR089C(identity) refseq:NP_014732.1|sgd:S000005615|dip:DIP-3801N|mint:P36017|ensemblfungi:YOR089C(gene)|ensemblfungi:YOR089C_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0061709"(reticulophagy)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:1EK0|ensemblgenomes:YOR089C(identity) - crc64:34D7DA0090C33F09 crc64:34D7DA0090C33F09 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:fo/U32XQLnHSVpuK48jddD4Kve4559292 rogid:fo/U32XQLnHSVpuK48jddD4Kve4559292 rigid:u2IfuO0zPd0M7UQh+nzYHjtrdTI false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32798 uniprotkb:P32798 intact:EBI-5006|uniprotkb:D6W314|ensemblfungi:YOR316C intact:EBI-5006|uniprotkb:D6W314|ensemblfungi:YOR316C psi-mi:cot1_yeast(display_long)|uniprotkb:COT1(gene name)|psi-mi:COT1(display_short)|uniprotkb:O6131(orf name)|uniprotkb:YOR316C(locus name) psi-mi:cot1_yeast(display_long)|uniprotkb:COT1(gene name)|psi-mi:COT1(display_short)|uniprotkb:O6131(orf name)|uniprotkb:YOR316C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21322287|imex:IM-26944-705 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005843|refseq:NP_014961.3|dip:DIP-7554N|mint:P32798|ensemblfungi:YOR316C(gene)|ensemblfungi:YOR316C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006824"(cobalt ion transport)|go:"GO:0006829"(zinc ion transport)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0015087"(cobalt ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|reactome:R-SCE-425410|ensemblgenomes:YOR316C(identity) sgd:S000005843|refseq:NP_014961.3|dip:DIP-7554N|mint:P32798|ensemblfungi:YOR316C(gene)|ensemblfungi:YOR316C_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006824"(cobalt ion transport)|go:"GO:0006829"(zinc ion transport)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0015087"(cobalt ion transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0071577"(zinc ion transmembrane transport)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|reactome:R-SCE-425410|ensemblgenomes:YOR316C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:HEIg6lhS698E9H3BJeESYAipNwA559292 rogid:HEIg6lhS698E9H3BJeESYAipNwA559292 rigid:gRJt4bqQScQo7E1kZZckce5fNTY false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q00955 uniprotkb:Q00955 intact:EBI-4814|uniprotkb:D6W1J1|ensemblfungi:YNR016C intact:EBI-4814|uniprotkb:D6W1J1|ensemblfungi:YNR016C psi-mi:acac_yeast(display_long)|uniprotkb:ACC1(gene name)|psi-mi:ACC1(display_short)|uniprotkb:ABP2(gene name synonym)|uniprotkb:MTR7(gene name synonym)|uniprotkb:N3175(orf name)|uniprotkb:YNR016C(locus name)|uniprotkb:FAS3(gene name synonym)|uniprotkb:Fatty acid synthetase 3(gene name synonym)|uniprotkb:mRNA transport-defective protein 7(gene name synonym) psi-mi:acac_yeast(display_long)|uniprotkb:ACC1(gene name)|psi-mi:ACC1(display_short)|uniprotkb:ABP2(gene name synonym)|uniprotkb:MTR7(gene name synonym)|uniprotkb:N3175(orf name)|uniprotkb:YNR016C(locus name)|uniprotkb:FAS3(gene name synonym)|uniprotkb:Fatty acid synthetase 3(gene name synonym)|uniprotkb:mRNA transport-defective protein 7(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21322275|imex:IM-26944-703 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014413.1|sgd:S000005299|dip:DIP-975N|mint:Q00955|ensemblfungi:YNR016C(gene)|ensemblfungi:YNR016C_mRNA(transcript)|go:"GO:0003989"(acetyl-CoA carboxylase activity)|go:"GO:0004075"(biotin carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0009317"(acetyl-CoA carboxylase complex)|go:"GO:0016743"(carboxyl- or carbamoyltransferase activity)|go:"GO:0042759"(long-chain fatty acid biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046872"(metal ion binding)|go:"GO:1905502"(acetyl-CoA binding)|go:"GO:2001295"(malonyl-CoA biosynthetic process)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001882(Biotin-binding site)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011762(Acetyl-coenzyme A carboxyltransferase, N-terminal)|interpro:IPR011763(Acetyl-coenzyme A carboxyltransferase, C-terminal)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013537(Acetyl-CoA carboxylase, central region)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR029045|interpro:IPR034733|rcsb pdb:1OD2|rcsb pdb:1OD4|rcsb pdb:1UYR|rcsb pdb:1UYS|rcsb pdb:1UYT|rcsb pdb:1UYV|rcsb pdb:1W2X|rcsb pdb:1W96|rcsb pdb:3H0J|rcsb pdb:3H0Q|rcsb pdb:3H0S|rcsb pdb:3K8X|rcsb pdb:3PGQ|rcsb pdb:3TV5|rcsb pdb:3TVU|rcsb pdb:3TVW|rcsb pdb:3TZ3|rcsb pdb:4WYO|rcsb pdb:4WZ8|rcsb pdb:5CS0|rcsb pdb:5CS4|rcsb pdb:5CSA|rcsb pdb:5CSK|rcsb pdb:5CSL|rcsb pdb:5CTB|rcsb pdb:5CTC|rcsb pdb:5CTE|rcsb pdb:5I6E|rcsb pdb:5TRC|reactome:R-SCE-163765|reactome:R-SCE-196780|reactome:R-SCE-200425|reactome:R-SCE-75105|rcsb pdb:1W93|ensemblgenomes:YNR016C(identity) refseq:NP_014413.1|sgd:S000005299|dip:DIP-975N|mint:Q00955|ensemblfungi:YNR016C(gene)|ensemblfungi:YNR016C_mRNA(transcript)|go:"GO:0003989"(acetyl-CoA carboxylase activity)|go:"GO:0004075"(biotin carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0009317"(acetyl-CoA carboxylase complex)|go:"GO:0016743"(carboxyl- or carbamoyltransferase activity)|go:"GO:0042759"(long-chain fatty acid biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046872"(metal ion binding)|go:"GO:1905502"(acetyl-CoA binding)|go:"GO:2001295"(malonyl-CoA biosynthetic process)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001882(Biotin-binding site)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011762(Acetyl-coenzyme A carboxyltransferase, N-terminal)|interpro:IPR011763(Acetyl-coenzyme A carboxyltransferase, C-terminal)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013537(Acetyl-CoA carboxylase, central region)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR029045|interpro:IPR034733|rcsb pdb:1OD2|rcsb pdb:1OD4|rcsb pdb:1UYR|rcsb pdb:1UYS|rcsb pdb:1UYT|rcsb pdb:1UYV|rcsb pdb:1W2X|rcsb pdb:1W96|rcsb pdb:3H0J|rcsb pdb:3H0Q|rcsb pdb:3H0S|rcsb pdb:3K8X|rcsb pdb:3PGQ|rcsb pdb:3TV5|rcsb pdb:3TVU|rcsb pdb:3TVW|rcsb pdb:3TZ3|rcsb pdb:4WYO|rcsb pdb:4WZ8|rcsb pdb:5CS0|rcsb pdb:5CS4|rcsb pdb:5CSA|rcsb pdb:5CSK|rcsb pdb:5CSL|rcsb pdb:5CTB|rcsb pdb:5CTC|rcsb pdb:5CTE|rcsb pdb:5I6E|rcsb pdb:5TRC|reactome:R-SCE-163765|reactome:R-SCE-196780|reactome:R-SCE-200425|reactome:R-SCE-75105|rcsb pdb:1W93|ensemblgenomes:YNR016C(identity) - crc64:0A335AAD9B1F8308 crc64:0A335AAD9B1F8308 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:zf1zvUJYyelChSf7blBKAnjVeoU559292 rogid:zf1zvUJYyelChSf7blBKAnjVeoU559292 rigid:NZiGgKss7zKOFpMDtlNNh48WRwI false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02829 uniprotkb:P02829 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 intact:EBI-8659|ensemblfungi:YPL240C|uniprotkb:D6W3D1 psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:hsp82_yeast(display_long)|uniprotkb:HSP90(gene name synonym)|uniprotkb:YPL240C(locus name)|uniprotkb:HSP82(gene name)|psi-mi:HSP82(display_short)|uniprotkb:Heat shock protein Hsp90 heat-inducible isoform(gene name synonym)|uniprotkb:82 kDa heat shock protein(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21322263|imex:IM-26944-619 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N|ensemblgenomes:YPL240C(identity) ensemblfungi:YPL240C(gene)|ensemblfungi:YPL240C_mRNA(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:1A4H|rcsb pdb:1AH6|rcsb pdb:1AH8|rcsb pdb:1AM1|rcsb pdb:1AMW|rcsb pdb:1BGQ|rcsb pdb:2WER|rcsb pdb:2XD6|rcsb pdb:2XX2|rcsb pdb:2XX4|rcsb pdb:2XX5|rcsb pdb:2YGA|rcsb pdb:2YGE|rcsb pdb:2YGF|rcsb pdb:3C0E|rcsb pdb:3C11|rcsb pdb:3FP2|rcsb pdb:4AS9|rcsb pdb:4ASA|rcsb pdb:4ASB|rcsb pdb:4ASF|rcsb pdb:2IWU|rcsb pdb:2IWX|rcsb pdb:2LSV|rcsb pdb:2VW5|rcsb pdb:2VWC|rcsb pdb:2WEP|rcsb pdb:4ASG|rcsb pdb:4CE1|rcsb pdb:4CE2|rcsb pdb:4CE3|rcsb pdb:5MGX|reactome:R-SCE-1474151|rcsb pdb:2WEQ|reactome:R-SCE-203615|reactome:R-SCE-3371497|reactome:R-SCE-3371511|reactome:R-SCE-3371571|reactome:R-SCE-5218920|reactome:R-SCE-6798695|reactome:R-SCE-844456|reactome:R-SCE-9009391|rcsb pdb:1HK7|rcsb pdb:1US7|rcsb pdb:1USU|rcsb pdb:1USV|rcsb pdb:1ZW9|rcsb pdb:1ZWH|rcsb pdb:2AKP|rcsb pdb:2BRC|rcsb pdb:2BRE|rcsb pdb:2CG9|rcsb pdb:2CGE|rcsb pdb:2CGF|rcsb pdb:2FXS|rcsb pdb:2IWS|refseq:NP_015084.1|sgd:S000006161|mint:P02829|dip:DIP-2262N|ensemblgenomes:YPL240C(identity) - crc64:D7C35676D668FB63 crc64:D7C35676D668FB63 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 rogid:K7/2Z6pLnYGlRxPVLyePuy/ECrk559292 rigid:+9zgCPuC6qL451ULG4/4+aoG5IU false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38009 uniprotkb:P38009 intact:EBI-14223|ensemblfungi:YMR120C|uniprotkb:D6VZU3 intact:EBI-14223|ensemblfungi:YMR120C|uniprotkb:D6VZU3 psi-mi:pur92_yeast(display_long)|uniprotkb:ADE17(gene name)|psi-mi:ADE17(display_short)|uniprotkb:YM8564.02C(orf name)|uniprotkb:YMR120C(locus name) psi-mi:pur92_yeast(display_long)|uniprotkb:ADE17(gene name)|psi-mi:ADE17(display_short)|uniprotkb:YM8564.02C(orf name)|uniprotkb:YMR120C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21322191|imex:IM-26944-419 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013839.1|sgd:S000004727|ensemblfungi:YMR120C(gene)|ensemblfungi:YMR120C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|reactome:R-SCE-73817|interpro:IPR036914|mint:P38009|dip:DIP-6288N|ensemblgenomes:YMR120C(identity) refseq:NP_013839.1|sgd:S000004727|ensemblfungi:YMR120C(gene)|ensemblfungi:YMR120C_mRNA(transcript)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|reactome:R-SCE-73817|interpro:IPR036914|mint:P38009|dip:DIP-6288N|ensemblgenomes:YMR120C(identity) - crc64:8ABA71761B512242 crc64:8ABA71761B512242 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:Bwp78WXy91CpBBXEqmM7MQV7XJk559292 rogid:Bwp78WXy91CpBBXEqmM7MQV7XJk559292 rigid:S5Uqloc7FTaA5w61fyDbN4VsnFQ false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P12683 uniprotkb:P12683 intact:EBI-8377|uniprotkb:D6W0K8|ensemblfungi:YML075C intact:EBI-8377|uniprotkb:D6W0K8|ensemblfungi:YML075C psi-mi:hmdh1_yeast(display_long)|uniprotkb:YML075C(locus name)|uniprotkb:HMG1(gene name)|psi-mi:HMG1(display_short) psi-mi:hmdh1_yeast(display_long)|uniprotkb:YML075C(locus name)|uniprotkb:HMG1(gene name)|psi-mi:HMG1(display_short) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21322239|imex:IM-26944-359 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013636.1|sgd:S000004540|mint:P12683|dip:DIP-4529N|ensemblfungi:YML075C(gene)|ensemblfungi:YML075C_mRNA(transcript)|go:"GO:0004420"("hydroxymethylglutaryl-CoA reductase (NADPH) activity")|go:"GO:0005635"(nuclear envelope)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008299"(isoprenoid biosynthetic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0019287"(isopentenyl diphosphate biosynthetic process, mevalonate pathway)|go:"GO:0034399"(nuclear periphery)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR002202(Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic)|interpro:IPR004554(Hydroxymethylglutaryl-CoA reductase, class I, catalytic)|interpro:IPR009023(Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding)|interpro:IPR009029(Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding)|interpro:IPR023074|interpro:IPR023076|interpro:IPR023282|interpro:IPR025583|reactome:R-SCE-191273|ensemblgenomes:YML075C(identity) refseq:NP_013636.1|sgd:S000004540|mint:P12683|dip:DIP-4529N|ensemblfungi:YML075C(gene)|ensemblfungi:YML075C_mRNA(transcript)|go:"GO:0004420"("hydroxymethylglutaryl-CoA reductase (NADPH) activity")|go:"GO:0005635"(nuclear envelope)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0008299"(isoprenoid biosynthetic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0019287"(isopentenyl diphosphate biosynthetic process, mevalonate pathway)|go:"GO:0034399"(nuclear periphery)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR002202(Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic)|interpro:IPR004554(Hydroxymethylglutaryl-CoA reductase, class I, catalytic)|interpro:IPR009023(Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding)|interpro:IPR009029(Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding)|interpro:IPR023074|interpro:IPR023076|interpro:IPR023282|interpro:IPR025583|reactome:R-SCE-191273|ensemblgenomes:YML075C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:S+uIZsMovFNW2+PxvV7m76Jbh+o559292 rogid:S+uIZsMovFNW2+PxvV7m76Jbh+o559292 rigid:nkXgZnQK/bZGKHSSNcdiWXeq51k false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38911 uniprotkb:P38911 intact:EBI-6951|uniprotkb:D6W0K9|ensemblfungi:YML074C intact:EBI-6951|uniprotkb:D6W0K9|ensemblfungi:YML074C psi-mi:fkbp3_yeast(display_long)|uniprotkb:YML074C(locus name)|uniprotkb:FPR3(gene name)|psi-mi:FPR3(display_short)|uniprotkb:NPI46(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Proline rotamase(gene name synonym)|uniprotkb:Nucleolar proline isomerase(gene name synonym)|uniprotkb:FKBP-70(gene name synonym) psi-mi:fkbp3_yeast(display_long)|uniprotkb:YML074C(locus name)|uniprotkb:FPR3(gene name)|psi-mi:FPR3(display_short)|uniprotkb:NPI46(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Proline rotamase(gene name synonym)|uniprotkb:Nucleolar proline isomerase(gene name synonym)|uniprotkb:FKBP-70(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21322227|imex:IM-26944-597 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013637.1|sgd:S000004539|dip:DIP-6578N|ensemblfungi:YML074C(gene)|ensemblfungi:YML074C_mRNA(transcript)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR023566|interpro:IPR041232|ensemblgenomes:YML074C(identity) refseq:NP_013637.1|sgd:S000004539|dip:DIP-6578N|ensemblfungi:YML074C(gene)|ensemblfungi:YML074C_mRNA(transcript)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR023566|interpro:IPR041232|ensemblgenomes:YML074C(identity) - crc64:A01D24DE0078FE11 crc64:A01D24DE0078FE11 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:4xZebf94akWQyMgPLbH6ExNGjoY559292 rogid:4xZebf94akWQyMgPLbH6ExNGjoY559292 rigid:K5aQMOxm3kDzGIq6jcEm0oER+Sg false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50094 uniprotkb:P50094 intact:EBI-9195|ensemblfungi:YML056C|uniprotkb:Q2VQW8|uniprotkb:D6VZB8 intact:EBI-9195|ensemblfungi:YML056C|uniprotkb:Q2VQW8|uniprotkb:D6VZB8 psi-mi:imdh4_yeast(display_long)|uniprotkb:IMD4(gene name)|psi-mi:IMD4(display_short)|uniprotkb:YM9958.06C(orf name)|uniprotkb:YML056C(locus name) psi-mi:imdh4_yeast(display_long)|uniprotkb:IMD4(gene name)|psi-mi:IMD4(display_short)|uniprotkb:YM9958.06C(orf name)|uniprotkb:YML056C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21322215|imex:IM-26944-357 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YML056C(gene)|ensemblfungi:YML056C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|reactome:R-SCE-6798695|reactome:R-SCE-73817|refseq:NP_013656.1|sgd:S000004520|dip:DIP-6458N|mint:P50094|ensemblgenomes:YML056C(identity) ensemblfungi:YML056C(gene)|ensemblfungi:YML056C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|reactome:R-SCE-6798695|reactome:R-SCE-73817|refseq:NP_013656.1|sgd:S000004520|dip:DIP-6458N|mint:P50094|ensemblgenomes:YML056C(identity) - crc64:A73D1E4EFE8AEAD9 crc64:A73D1E4EFE8AEAD9 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:S70ravpil5p+waXS1zst4Ii27dY559292 rogid:S70ravpil5p+waXS1zst4Ii27dY559292 rigid:kg1rrGnNmC0E8fR9PhfBx/7Lqcw false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12123 uniprotkb:Q12123 intact:EBI-38701|uniprotkb:D6W2M9|ensemblfungi:YOR173W intact:EBI-38701|uniprotkb:D6W2M9|ensemblfungi:YOR173W psi-mi:dcs2_yeast(display_long)|uniprotkb:Histidine triad protein(gene name synonym)|uniprotkb:DCS2(gene name)|psi-mi:DCS2(display_short)|uniprotkb:Protein Dcs2p(gene name synonym)|uniprotkb:O3625(orf name)|uniprotkb:YOR173W(locus name) psi-mi:dcs2_yeast(display_long)|uniprotkb:Histidine triad protein(gene name synonym)|uniprotkb:DCS2(gene name)|psi-mi:DCS2(display_short)|uniprotkb:Protein Dcs2p(gene name synonym)|uniprotkb:O3625(orf name)|uniprotkb:YOR173W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21322203|imex:IM-26944-177 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014816.2|sgd:S000005699|mint:Q12123|dip:DIP-4135N|ensemblfungi:YOR173W(gene)|ensemblfungi:YOR173W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007584"(response to nutrient)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009408"(response to heat)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0090342"(regulation of cell aging)|interpro:IPR008594(Scavenger mRNA decapping enzyme)|interpro:IPR011145(Scavenger mRNA decapping enzyme, N-terminal)|interpro:IPR019808|interpro:IPR036265|ensemblgenomes:YOR173W(identity) refseq:NP_014816.2|sgd:S000005699|mint:Q12123|dip:DIP-4135N|ensemblfungi:YOR173W(gene)|ensemblfungi:YOR173W_mRNA(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007584"(response to nutrient)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009408"(response to heat)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050072"("m7G(5')pppN diphosphatase activity")|go:"GO:0090342"(regulation of cell aging)|interpro:IPR008594(Scavenger mRNA decapping enzyme)|interpro:IPR011145(Scavenger mRNA decapping enzyme, N-terminal)|interpro:IPR019808|interpro:IPR036265|ensemblgenomes:YOR173W(identity) - crc64:B76D89C0816019A4 crc64:B76D89C0816019A4 figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:aQPcvWgnqKehPYywuexsUkmjU9Q559292 rogid:aQPcvWgnqKehPYywuexsUkmjU9Q559292 rigid:IOMFIOxbBT6eyi1sCI5Ni/morVE false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38426 uniprotkb:P38426 intact:EBI-19448|uniprotkb:D6W087|uniprotkb:Q6B1W2|ensemblfungi:YMR261C intact:EBI-19448|uniprotkb:D6W087|uniprotkb:Q6B1W2|ensemblfungi:YMR261C psi-mi:tps3_yeast(display_long)|uniprotkb:TPS3(gene name)|psi-mi:TPS3(display_short)|uniprotkb:YMR261C(locus name)|uniprotkb:YM8156.03C(orf name)|uniprotkb:Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 115 kDa subunit(gene name synonym) psi-mi:tps3_yeast(display_long)|uniprotkb:TPS3(gene name)|psi-mi:TPS3(display_short)|uniprotkb:YMR261C(locus name)|uniprotkb:YM8156.03C(orf name)|uniprotkb:Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 115 kDa subunit(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21322251|imex:IM-26944-599 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013988.1|sgd:S000004874|ensemblfungi:YMR261C(gene)|ensemblfungi:YMR261C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005946"("alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)")|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0016311"(dephosphorylation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR001830(Glycosyl transferase, family 20)|interpro:IPR003337(Trehalose-phosphatase)|interpro:IPR036412|dip:DIP-891N|mint:P38426|ensemblgenomes:YMR261C(identity) refseq:NP_013988.1|sgd:S000004874|ensemblfungi:YMR261C(gene)|ensemblfungi:YMR261C_mRNA(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005946"("alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)")|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0016311"(dephosphorylation)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR001830(Glycosyl transferase, family 20)|interpro:IPR003337(Trehalose-phosphatase)|interpro:IPR036412|dip:DIP-891N|mint:P38426|ensemblgenomes:YMR261C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:aY+Gu2+xxYxfe40pjJ1KTaYbDxM559292 rogid:aY+Gu2+xxYxfe40pjJ1KTaYbDxM559292 rigid:mR7E0oiSYRyAGF2jNVHG6xTn8y8 false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P24784 uniprotkb:P24784 intact:EBI-5596|uniprotkb:P20446|uniprotkb:D6W3P9|ensemblfungi:YPL119C intact:EBI-5596|uniprotkb:P20446|uniprotkb:D6W3P9|ensemblfungi:YPL119C psi-mi:dbp1_yeast(display_long)|uniprotkb:DBP1(gene name)|psi-mi:DBP1(display_short)|uniprotkb:YPL119C(locus name)|uniprotkb:LPH8C(orf name)|uniprotkb:DEAD box protein 1(gene name synonym)|uniprotkb:Helicase CA1(gene name synonym) psi-mi:dbp1_yeast(display_long)|uniprotkb:DBP1(gene name)|psi-mi:DBP1(display_short)|uniprotkb:YPL119C(locus name)|uniprotkb:LPH8C(orf name)|uniprotkb:DEAD box protein 1(gene name synonym)|uniprotkb:Helicase CA1(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21322335|imex:IM-26944-519 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015206.1|sgd:S000006040|dip:DIP-2576N|mint:P24784|ensemblfungi:YPL119C(gene)|ensemblfungi:YPL119C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044763|ensemblgenomes:YPL119C(identity) refseq:NP_015206.1|sgd:S000006040|dip:DIP-2576N|mint:P24784|ensemblfungi:YPL119C(gene)|ensemblfungi:YPL119C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901195"(positive regulation of formation of translation preinitiation complex)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044763|ensemblgenomes:YPL119C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:8TFwSQq3dopTasOH0G/KZ12DDGE559292 rogid:8TFwSQq3dopTasOH0G/KZ12DDGE559292 rigid:Non/5x2067LAxviC5ycJapfw+9s false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12166 uniprotkb:Q12166 intact:EBI-37359|uniprotkb:D6W2G7|ensemblfungi:YOR108W intact:EBI-37359|uniprotkb:D6W2G7|ensemblfungi:YOR108W psi-mi:leu9_yeast(display_long)|uniprotkb:LEU9(gene name)|psi-mi:LEU9(display_short)|uniprotkb:YOR3227w(orf name)|uniprotkb:Alpha-isopropylmalate synthase 2(gene name synonym)|uniprotkb:Alpha-IPM synthase 2(gene name synonym)|uniprotkb:Alpha-isopropylmalate synthase II(gene name synonym)|uniprotkb:YOR108W(locus name) psi-mi:leu9_yeast(display_long)|uniprotkb:LEU9(gene name)|psi-mi:LEU9(display_short)|uniprotkb:YOR3227w(orf name)|uniprotkb:Alpha-isopropylmalate synthase 2(gene name synonym)|uniprotkb:Alpha-IPM synthase 2(gene name synonym)|uniprotkb:Alpha-isopropylmalate synthase II(gene name synonym)|uniprotkb:YOR108W(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21322311|imex:IM-26944-439 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014751.1|sgd:S000005634|mint:Q12166|dip:DIP-4153N|ensemblfungi:YOR108W(gene)|ensemblfungi:YOR108W_mRNA(transcript)|go:"GO:0003852"(2-isopropylmalate synthase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0009082"(branched-chain amino acid biosynthetic process)|go:"GO:0009098"(leucine biosynthetic process)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR002034(Alpha-isopropylmalate/homocitrate synthase, conserved site)|interpro:IPR005668(Yeast 2-isopropylmalate synthase)|interpro:IPR013709("2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain")|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR036230|interpro:IPR039371|ensemblgenomes:YOR108W(identity) refseq:NP_014751.1|sgd:S000005634|mint:Q12166|dip:DIP-4153N|ensemblfungi:YOR108W(gene)|ensemblfungi:YOR108W_mRNA(transcript)|go:"GO:0003852"(2-isopropylmalate synthase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0009082"(branched-chain amino acid biosynthetic process)|go:"GO:0009098"(leucine biosynthetic process)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR002034(Alpha-isopropylmalate/homocitrate synthase, conserved site)|interpro:IPR005668(Yeast 2-isopropylmalate synthase)|interpro:IPR013709("2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain")|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR036230|interpro:IPR039371|ensemblgenomes:YOR108W(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:xem/K524HzAGsD4IT+y2KU/l7gI559292 rogid:xem/K524HzAGsD4IT+y2KU/l7gI559292 rigid:nuNpfwGXeZLkh9WFHc9xTEeWIHQ false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02969 uniprotkb:Q02969 intact:EBI-37452|uniprotkb:Q6B2A9|uniprotkb:D6W3Q5|ensemblfungi:YPL112C intact:EBI-37452|uniprotkb:Q6B2A9|uniprotkb:D6W3Q5|ensemblfungi:YPL112C psi-mi:pex25_yeast(display_long)|uniprotkb:YPL112C(locus name)|uniprotkb:PEX25(gene name)|psi-mi:PEX25(display_short)|uniprotkb:Peroxin-25(gene name synonym) psi-mi:pex25_yeast(display_long)|uniprotkb:YPL112C(locus name)|uniprotkb:PEX25(gene name)|psi-mi:PEX25(display_short)|uniprotkb:Peroxin-25(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Marchant et al. (2019) pubmed:31454312|imex:IM-26944 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-21322323|imex:IM-26944-517 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000006033|refseq:NP_015213.1|dip:DIP-5292N|mint:Q02969|ensemblfungi:YPL112C(gene)|ensemblfungi:YPL112C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0016559"(peroxisome fission)|go:"GO:0044375"(regulation of peroxisome size)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|ensemblgenomes:YPL112C(identity) sgd:S000006033|refseq:NP_015213.1|dip:DIP-5292N|mint:Q02969|ensemblfungi:YPL112C(gene)|ensemblfungi:YPL112C_mRNA(transcript)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005779"(integral component of peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0016559"(peroxisome fission)|go:"GO:0044375"(regulation of peroxisome size)|interpro:IPR008733(Peroxisomal biogenesis factor 11)|ensemblgenomes:YPL112C(identity) - - - figure legend:Fig. 2,Table S1, Table S2, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2019/04/04 2019/04/16 rogid:42Jce4KR0S5WehK1GVfqhG+Cqbo559292 rogid:42Jce4KR0S5WehK1GVfqhG+Cqbo559292 rigid:2HdDA4ZBVVdvSaMaHHRG6HEMBvs false fusion protein:?-? fusion protein:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)