#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P49765	uniprotkb:P49765	intact:EBI-2799898|uniprotkb:Q16528|ensembl:ENSP00000311127	intact:EBI-2799898|uniprotkb:Q16528|ensembl:ENSP00000311127	psi-mi:vegfb_human(display_long)|uniprotkb:VRF(gene name synonym)|uniprotkb:VEGF-related factor(gene name synonym)|uniprotkb:VEGFB(gene name)|psi-mi:VEGFB(display_short)	psi-mi:vegfb_human(display_long)|uniprotkb:VRF(gene name synonym)|uniprotkb:VEGF-related factor(gene name synonym)|uniprotkb:VEGFB(gene name)|psi-mi:VEGFB(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	Iyer et al. (2006)	pubmed:16616187|imex:IM-28495	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-25777206|wwpdb:2C7W|imex:IM-28495-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003368.1|refseq:NP_001230662.1|dip:DIP-6045N|interpro:IPR000072("Platelet-derived growth factor (PDGF)")|interpro:IPR023581|interpro:IPR029034|rcsb pdb:2C7W|rcsb pdb:2VWE|rcsb pdb:2XAC|rcsb pdb:6TKK|reactome:R-HSA-114608|reactome:R-HSA-194313|reactome:R-HSA-195399|ensembl:ENSG00000173511(gene)|ensembl:ENST00000309422(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0005172"(vascular endothelial growth factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0008083"(growth factor activity)|go:"GO:0008201"(heparin binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030949"(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0035470"(positive regulation of vascular wound healing)|go:"GO:0038084"(vascular endothelial growth factor signaling pathway)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043183"(vascular endothelial growth factor receptor 1 binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050930"(induction of positive chemotaxis)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060754"(positive regulation of mast cell chemotaxis)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_003368.1|refseq:NP_001230662.1|dip:DIP-6045N|interpro:IPR000072("Platelet-derived growth factor (PDGF)")|interpro:IPR023581|interpro:IPR029034|rcsb pdb:2C7W|rcsb pdb:2VWE|rcsb pdb:2XAC|rcsb pdb:6TKK|reactome:R-HSA-114608|reactome:R-HSA-194313|reactome:R-HSA-195399|ensembl:ENSG00000173511(gene)|ensembl:ENST00000309422(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0005172"(vascular endothelial growth factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006493"(protein O-linked glycosylation)|go:"GO:0008083"(growth factor activity)|go:"GO:0008201"(heparin binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030949"(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0035470"(positive regulation of vascular wound healing)|go:"GO:0038084"(vascular endothelial growth factor signaling pathway)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043183"(vascular endothelial growth factor receptor 1 binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050930"(induction of positive chemotaxis)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060754"(positive regulation of mast cell chemotaxis)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	-	-	-	figure legend:Fig 1, Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2019/08/05	2020/08/13	rogid:kyRPokGAlmZTWgRwTCTXmsCeAAg9606	rogid:kyRPokGAlmZTWgRwTCTXmsCeAAg9606	rigid:KpxMJScB0GVYntHeIe1vRuH4cSg	false	binding-associated region:10-108	binding-associated region:10-108	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)