#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q3UHD9	uniprotkb:Q3UTJ2	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-8345744|uniprotkb:Q80TS1|intact:MINT-1853612|uniprotkb:Q3USC6|uniprotkb:Q8BX47|uniprotkb:Q8CHU0|uniprotkb:Q8BLW9|intact:MINT-4116161|uniprotkb:Q8BJL6|uniprotkb:Q8BJU3	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:srbs2_mouse(display_long)|uniprotkb:Sorbs2(gene name)|psi-mi:Sorbs2(display_short)|uniprotkb:Arg/Abl-interacting protein 2(gene name synonym)|uniprotkb:Argbp2(gene name synonym)|uniprotkb:Kiaa0777(gene name synonym)|uniprotkb:Arg-binding protein 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001297636.1|interpro:IPR003127(Sorbin-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR028506|interpro:IPR036028|mint:Q3UTJ2|refseq:XP_006509449.1|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:1904393"(regulation of skeletal muscle acetylcholine-gated channel clustering)|interpro:IPR001452(Src homology-3)|hgnc:"MGI:1924574"(identity)	go:"GO:0014069"(postsynaptic density)	-	comment:"fragmentation type: fragment"	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:2sKDQux/2IV7mW8l6LK36D3qlqw10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q8CHG7	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-7027510|ensembl:ENSMUSP00000114119|intact:MINT-4133098|uniprotkb:E9QMD0	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:rpgf2_mouse(display_long)|uniprotkb:Rapgef2(gene name)|psi-mi:Rapgef2(display_short)|uniprotkb:Kiaa0313(gene name synonym)|uniprotkb:Pdzgef1(gene name synonym)|uniprotkb:Neural RAP guanine nucleotide exchange protein(gene name synonym)|uniprotkb:PDZ domain-containing guanine nucleotide exchange factor 1(gene name synonym)|uniprotkb:Cyclic nucleotide ras GEF(gene name synonym)|uniprotkb:RA-GEF-1(gene name synonym)|uniprotkb:Ras/Rap1-associating GEF-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:XP_006502317.1|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071321"(cellular response to cGMP)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:1901888"(regulation of cell junction assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000481"(positive regulation of cAMP-dependent protein kinase activity)|go:"GO:2000670"(positive regulation of dendritic cell apoptotic process)|go:"GO:2001214"(positive regulation of vasculogenesis)|go:"GO:0050699"(WW domain binding)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR000159(Ras-association)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR018490|interpro:IPR023578|interpro:IPR029071|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030739|interpro:IPR036034|mint:Q8CHG7|reactome:R-MMU-5673001|ensembl:ENSMUSG00000062232(gene)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0021591"(ventricular system development)|go:"GO:0021884"(forebrain neuron development)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031547"(brain-derived neurotrophic factor receptor signaling pathway)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032486"(Rap protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0038180"(nerve growth factor signaling pathway)|ensembl:ENSMUST00000118100(transcript)|go:"GO:0001568"(blood vessel development)|go:"GO:0001764"(neuron migration)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043950"(positive regulation of cAMP-mediated signaling)|go:"GO:0045202"(synapse)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0048022"(negative regulation of melanin biosynthetic process)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|hgnc:"MGI:2659071"(identity)	go:"GO:0014069"(postsynaptic density)	-	comment:"fragmentation type: fragment"|comment:mint|comment:homomint|function:"Guanine nucleotide exchange factor (GEF) for Rap1, Rap1B and Rap2 GTPases"	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:gH1WVMkcR44bJMCVvh7NctDb5KI10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q8R5H6	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-774719|uniprotkb:Q91W51|uniprotkb:Q9ERQ9|ensembl:ENSMUSP00000019975|ensembl:ENSMUSP00000101148	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:wasf1_mouse(display_long)|uniprotkb:Protein WAVE-1(gene name synonym)|uniprotkb:Wasf1(gene name)|psi-mi:Wasf1(display_short)|uniprotkb:Wave1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_114083.1|refseq:XP_006512995.1|ensembl:ENSMUSG00000019831(gene)|ensembl:ENSMUST00000019975(transcript)|ensembl:ENSMUST00000105509(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031209"(SCAR complex)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051388"(positive regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:0097484"(dendrite extension)|go:"GO:0098794"(postsynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098939"(dendritic transport of mitochondrion)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR028288|mint:Q8R5H6|reactome:R-MMU-2029482|reactome:R-MMU-4420097|reactome:R-MMU-5663213|reactome:R-MMU-9013149|reactome:R-MMU-9013423|hgnc:"MGI:1890563"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:t+4F2ap7lNjE/AGuIwMhel4YknU10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q0KL02-3	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16736247	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:q0kl02-3(display_long)|uniprotkb:Trio(gene name)|psi-mi:Trio(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	intact:EBI-16725543(isoform-parent)|hgnc:"MGI:1927230"(identity)	go:"GO:0014069"(postsynaptic density)	-	isoform-comment:No experimental confirmation available.	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:qbxBZT0BUNqZOG52EvFv7I4bxGw10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:E0CZD7	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16736231|ensembl:ENSMUSP00000125466	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:e0czd7_mouse(display_long)|uniprotkb:Tnik(gene name)|psi-mi:Tnik(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000027692(gene)|ensembl:ENSMUST00000159308(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001180(Citron-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|hgnc:"MGI:1916264"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:tlAIU+MDWEYx+qQkWrzrYV8W9yg10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:E9Q7S0	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16736202|ensembl:ENSMUSP00000128997	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:e9q7s0_mouse(display_long)|uniprotkb:Synj1(gene name)|psi-mi:Synj1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000022973(gene)|ensembl:ENSMUST00000170853(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0098793"(presynapse)|interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002013(Synaptojanin, N-terminal)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015047(Region of unknown function DUF1866)|interpro:IPR034971|interpro:IPR034972|interpro:IPR035979|interpro:IPR036691|refseq:NP_001038980.1|hgnc:"MGI:1354961"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:Rd53lggxVbgQZGOTsLY7XU3SfTc10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:F6SEU4	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-5797569|ensembl:ENSMUSP00000141686	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442|hgnc:"MGI:3039785"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q6ZWR6-5	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-10760805|ensembl:ENSMUSP00000039440	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:q6zwr6-5(display_long)|uniprotkb:Enaptin(gene name synonym)|uniprotkb:Myocyte nuclear envelope protein 1(gene name synonym)|uniprotkb:Nuclear envelope spectrin repeat protein 1(gene name synonym)|uniprotkb:Synaptic nuclear envelope protein 1(gene name synonym)|uniprotkb:Enaptin-165(isoform synonym)|uniprotkb:Syne1(gene name)|psi-mi:Syne1(display_short)|uniprotkb:KASH domain-containing protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	intact:EBI-10760754(isoform-parent)|ensembl:ENSMUSG00000096054(gene)|ensembl:ENSMUST00000041639(transcript)|hgnc:"MGI:1927152"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:yrXDsNQUAyf2nzhIIsEM5FaYheo10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P05480	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-298680|ensembl:ENSMUSP00000029175|ensembl:ENSMUSP00000105157|ensembl:ENSMUSP00000105159|uniprotkb:Q2M4I4|intact:EBI-7361449|intact:MINT-142018|uniprotkb:F8WI90	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:src_mouse(display_long)|uniprotkb:Src(gene name)|psi-mi:Src(display_short)|uniprotkb:pp60c-src(gene name synonym)|uniprotkb:Proto-oncogene c-Src(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009615"(response to virus)|go:"GO:0010447"(response to acidic pH)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0020037"(heme binding)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035306"(positive regulation of dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036035"(osteoclast development)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042476"(odontogenesis)|go:"GO:0042493"|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045056"(transcytosis)|go:"GO:0045087"(innate immune response)|go:"GO:0045453"(bone resorption)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048477"(oogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051222"(positive regulation of protein transport)|go:"GO:0051385"(response to mineralocorticoid)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051902"(negative regulation of mitochondrial depolarization)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060065"(uterus development)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060491"(regulation of cell projection assembly)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070700"(BMP receptor binding)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071253"(connexin binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071393"(cellular response to progesterone stimulus)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0086098"(angiotensin-activated signaling pathway involved in heart process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902533"(positive regulation of intracellular signal transduction)|go:"GO:2000386"(positive regulation of ovarian follicle development)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000588"(positive regulation of platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|go:"GO:2001286"(regulation of caveolin-mediated endocytosis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|mint:P05480|rcsb pdb:6F3F|reactome:R-MMU-1227986|reactome:R-MMU-1251985|reactome:R-MMU-1253288|reactome:R-MMU-1257604|reactome:R-MMU-1295596|reactome:R-MMU-1433557|reactome:R-MMU-1433559|reactome:R-MMU-177929|reactome:R-MMU-180292|reactome:R-MMU-186763|reactome:R-MMU-191650|reactome:R-MMU-2029481|reactome:R-MMU-210990|reactome:R-MMU-354192|reactome:R-MMU-354194|reactome:R-MMU-372708|reactome:R-MMU-389356|reactome:R-MMU-389513|reactome:R-MMU-3928662|reactome:R-MMU-3928663|reactome:R-MMU-3928664|reactome:R-MMU-3928665|reactome:R-MMU-418592|reactome:R-MMU-418594|reactome:R-MMU-418885|reactome:R-MMU-430116|reactome:R-MMU-437239|reactome:R-MMU-4420097|reactome:R-MMU-456926|reactome:R-MMU-5218921|reactome:R-MMU-5607764|reactome:R-MMU-5663220|reactome:R-MMU-5673000|reactome:R-MMU-5674135|reactome:R-MMU-6811558|reactome:R-MMU-69231|reactome:R-MMU-8853659|reactome:R-MMU-8874081|reactome:R-MMU-8934903|reactome:R-MMU-8941858|reactome:R-MMU-9009391|reactome:R-MMU-9603381|ensembl:ENSMUSG00000027646(gene)|ensembl:ENSMUST00000029175(transcript)|ensembl:ENSMUST00000109531(transcript)|ensembl:ENSMUST00000109533(transcript)|go:"GO:0001545"(primary ovarian follicle growth)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002102"(podosome)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|refseq:NP_001020566.1|refseq:NP_033297.2|dip:DIP-31071N|hgnc:"MGI:98397"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:SY8bQUpE/ni7hRMp4F02ygRsU7Q10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q62417	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-2365368|uniprotkb:Q80TF8|uniprotkb:Q8BZI3|uniprotkb:Q8K3Y2|uniprotkb:Q921F8|uniprotkb:Q9Z0Z8|uniprotkb:Q9Z0Z9	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:srbs1_mouse(display_long)|uniprotkb:Sorbs1(gene name)|psi-mi:Sorbs1(display_short)|uniprotkb:Kiaa1296(gene name synonym)|uniprotkb:Sh3d5(gene name synonym)|uniprotkb:Ponsin(gene name synonym)|uniprotkb:c-Cbl-associated protein(gene name synonym)|uniprotkb:SH3 domain protein 5(gene name synonym)|uniprotkb:SH3P12(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001030134.1|refseq:NP_001030135.1|refseq:NP_001030136.1|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR035606|interpro:IPR035610|interpro:IPR035611|interpro:IPR036028|mint:Q62417|go:"GO:0001725"(stress fiber)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005899"(insulin receptor complex)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016600"(flotillin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904393"(regulation of skeletal muscle acetylcholine-gated channel clustering)|reactome:R-MMU-445355|hgnc:"MGI:700014"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:3+0ZfSkNB+9ujOF3uyXmP2ovl8A10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q4ACU6	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-771450|uniprotkb:Q69ZD8|intact:EBI-8401154|intact:MINT-4130064|uniprotkb:F8S0X0|uniprotkb:F8S0X2|uniprotkb:F8S0X3|uniprotkb:F8S0X5|uniprotkb:F8S0X6|uniprotkb:Q9JJZ3|uniprotkb:S6BMD3|uniprotkb:S6CCV8|ensembl:ENSMUSP00000104932	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:shan3_mouse(display_long)|uniprotkb:Proline-rich synapse-associated protein 2(gene name synonym)|uniprotkb:SPANK-2(gene name synonym)|uniprotkb:Shank3(gene name)|psi-mi:Shank3(display_short)|uniprotkb:Kiaa1650(gene name synonym)|uniprotkb:Prosap2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_067398.2|dip:DIP-32262N|ensembl:ENSMUSG00000022623(gene)|ensembl:ENSMUST00000109309(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001838"(embryonic epithelial tube formation)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007416"(synapse assembly)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0021773"(striatal medium spiny neuron differentiation)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030534"(adult behavior)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0051835"(positive regulation of synapse structural plasticity)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097107"(postsynaptic density assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097114"(NMDA glutamate receptor clustering)|go:"GO:0097117"(guanylate kinase-associated protein clustering)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035640"(exploration behavior)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0040011"(locomotion)|go:"GO:0042297"(vocal learning)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043621"(protein self-association)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045794"(negative regulation of cell volume)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048170"(positive regulation of long-term neuronal synaptic plasticity)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1900451"(positive regulation of glutamate receptor signaling pathway)|go:"GO:1900452"(regulation of long-term synaptic depression)|go:"GO:1904717"(regulation of AMPA glutamate receptor clustering)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|go:"GO:2000822"(regulation of behavioral fear response)|go:"GO:2000969"(positive regulation of AMPA receptor activity)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|mint:Q4ACU6|rcsb pdb:3O5N|rcsb pdb:5IZU|rcsb pdb:6KYH|rcsb pdb:6KYK|reactome:R-MMU-6794361|reactome:R-MMU-8853659|hgnc:"MGI:1930016"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:40CZZZ4qetQSv6a6gsUMVeL0c+o10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q80Z38	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-770338|uniprotkb:E9QPH7|uniprotkb:Q3UTK4|uniprotkb:Q5DU07	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:shan2_mouse(display_long)|uniprotkb:Cortactin-binding protein 1(gene name synonym)|uniprotkb:Shank2(gene name)|psi-mi:Shank2(display_short)|uniprotkb:Cortbp1(gene name synonym)|uniprotkb:Kiaa1022(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001074839.2|refseq:NP_001106844.2|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR001452(Src homology-3)|refseq:XP_006508596.1|reactome:R-MMU-6794361|interpro:IPR036028|interpro:IPR036034|interpro:IPR041489|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007416"(synapse assembly)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030426"(growth cone)|go:"GO:0030534"(adult behavior)|go:"GO:0031526"(brush border membrane)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035640"(exploration behavior)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0071625"(vocalization behavior)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0043005"(neuron projection)|hgnc:"MGI:2671987"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:OTohbAMxKtx7/WWwWXDc+c24HvQ10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:D3YZU1	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-2314988|ensembl:ENSMUSP00000103571	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:shan1_mouse(display_long)|uniprotkb:Shank1(gene name)|psi-mi:Shank1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001029287.1|refseq:XP_006540927.1|ensembl:ENSMUSG00000038738(gene)|ensembl:ENSMUST00000107938(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007616"(long-term memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008306"(associative learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0031877"(somatostatin receptor binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046959"(habituation)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0050894"(determination of affect)|go:"GO:0060013"(righting reflex)|go:"GO:0060074"(synapse maturation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|reactome:R-MMU-6794361|hgnc:"MGI:3613677"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:TbxBmjjabypLqTlAx9zbkSAAzpk10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:O55131	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-772161	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:sept7_mouse(display_long)|uniprotkb:Septin7(gene name)|psi-mi:Septin7(display_short)|uniprotkb:CDC10 protein homolog(gene name synonym)|uniprotkb:Cdc10(gene name synonym)|uniprotkb:Sept7(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001192296.1|interpro:IPR016491(Septin)|interpro:IPR008115(Septin 7)|interpro:IPR030379|interpro:IPR027417|mint:O55131|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000776"(kinetochore)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005930"(axoneme)|go:"GO:0005938"(cell cortex)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0030496"(midbody)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031105"(septin complex)|go:"GO:0031270"(pseudopodium retraction)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032160"(septin filament array)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0043679"(axon terminus)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0048668"(collateral sprouting)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|reactome:R-MMU-5687128|hgnc:"MGI:1335094"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:VULb4UyoWVn5vRWIzERa9YQJIYo10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q9Z2Q6	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-772125|uniprotkb:Q3UYG4|uniprotkb:Q6PB74|uniprotkb:B2RUC5|ensembl:ENSMUSP00000094750	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:sept5_mouse(display_long)|uniprotkb:Septin5(gene name)|psi-mi:Septin5(display_short)|uniprotkb:Cell division control-related protein 1(gene name synonym)|uniprotkb:Peanut-like protein 1(gene name synonym)|uniprotkb:Pnutl1(gene name synonym)|uniprotkb:Sept5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_998779.2|ensembl:ENSMUSG00000072214(gene)|ensembl:ENSMUST00000096987(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0005940"(septin ring)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019003"(GDP binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030534"(adult behavior)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035176"(social behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043679"(axon terminus)|go:"GO:0044305"(calyx of Held)|go:"GO:0045202"(synapse)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0098793"(presynapse)|go:"GO:0099148"(regulation of synaptic vesicle docking)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030647|mint:Q9Z2Q6|hgnc:"MGI:1195461"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:9ZY1BrCZ/7+83bn/q3OQkZoi8pg10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q9Z268	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-2013210|uniprotkb:Q99K69|ensembl:ENSMUSP00000031606|ensembl:ENSMUSP00000123266	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:rasl1_mouse(display_long)|uniprotkb:Rasal1(gene name)|psi-mi:Rasal1(display_short)|uniprotkb:Rasal(gene name synonym)|uniprotkb:RAS protein activator like 1(gene name synonym)|uniprotkb:Ras GTPase-activating-like protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:XP_006530272.1|refseq:XP_006530273.1|refseq:NP_038860.2|ensembl:ENSMUSG00000029602(gene)|ensembl:ENSMUST00000031606(transcript)|ensembl:ENSMUST00000156722(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1903861"(positive regulation of dendrite extension)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001562(Tec/Btk)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023152|interpro:IPR028555|interpro:IPR035892|interpro:IPR037776|interpro:IPR039360|mint:Q9Z268|reactome:R-MMU-5658442|hgnc:"MGI:1330842"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:VbTtsNfJC0uXiZYAtnOIFBPfLkA10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q6GYP7-6	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16736192	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:q6gyp7-6(display_long)|uniprotkb:GAP-related-interacting partner to E12(gene name synonym)|uniprotkb:GTPase-activating RapGAP domain-like 1(gene name synonym)|uniprotkb:Tuberin-like protein 1(gene name synonym)|uniprotkb:p240(gene name synonym)|uniprotkb:Ralgapa1(gene name)|psi-mi:Ralgapa1(display_short)|uniprotkb:Garnl1(gene name synonym)|uniprotkb:Kiaa0884(gene name synonym)|uniprotkb:Tulip1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	intact:EBI-8329354(isoform-parent)|hgnc:"MGI:1931050"(identity)	go:"GO:0014069"(postsynaptic density)	-	isoform-comment:May be a partial isoform 1. No experimental confirmation available.	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:+319pDOGGFM9rxESoaH/7mme8/410090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:E9Q2A6	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16736131|ensembl:ENSMUSP00000086661	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:e9q2a6_mouse(display_long)|uniprotkb:Ptk2b(gene name)|psi-mi:Ptk2b(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000059456(gene)|ensembl:ENSMUST00000089250(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0002688"(regulation of leukocyte chemotaxis)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007172"(signal complex assembly)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030500"(regulation of bone mineralization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042995"(cell projection)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR005189(Focal adhesion targeting region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019748|interpro:IPR019749|interpro:IPR020635|interpro:IPR029071|interpro:IPR030610|interpro:IPR035963|interpro:IPR036137|interpro:IPR041784|interpro:IPR041390|refseq:NP_766086.2|hgnc:"MGI:104908"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:5LpFLxkeBrge1Jg2mPu2dqGAiBo10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P34152-9	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16736120	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:p34152-9(display_long)|uniprotkb:Focal adhesion kinase-related nonkinase(gene name synonym)|uniprotkb:Protein-tyrosine kinase 2(gene name synonym)|uniprotkb:p125FAK(gene name synonym)|uniprotkb:pp125FAK(gene name synonym)|uniprotkb:FRNK(isoform synonym)|uniprotkb:Ptk2(gene name)|psi-mi:Ptk2(display_short)|uniprotkb:Fadk(gene name synonym)|uniprotkb:Fak(gene name synonym)|uniprotkb:Fak1(gene name synonym)|uniprotkb:Kiaa4203(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	intact:EBI-77070(isoform-parent)|hgnc:"MGI:95481"(identity)	go:"GO:0014069"(postsynaptic density)	-	isoform-comment:Produced by alternative promoter usage.	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:5ushBRaT95lhty9dIrunrwHFves10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P63318	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-397096|uniprotkb:P05697|ensembl:ENSMUSP00000097874	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:kpcg_mouse(display_long)|uniprotkb:Pkcc(gene name synonym)|uniprotkb:Pkcg(gene name synonym)|uniprotkb:Prkcc(gene name synonym)|uniprotkb:Prkcg(gene name)|psi-mi:Prkcg(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_035232.1|ensembl:ENSMUSG00000078816(gene)|ensembl:ENSMUST00000100301(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0032095"(regulation of response to food)|go:"GO:0032425"(positive regulation of mismatch repair)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0043278"(response to morphine)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0044305"(calyx of Held)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048265"(response to pain)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060384"(innervation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0099171"(presynaptic modulation of chemical synaptic transmission)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:0005829"(cytosol)|go:"GO:1990911"(response to psychosocial stress)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014375(Protein kinase C, alpha/beta/gamma types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030425"(dendrite)|go:"GO:0031397"(negative regulation of protein ubiquitination)|interpro:IPR020454|interpro:IPR035892|mint:P63318|reactome:R-MMU-111933|reactome:R-MMU-114516|reactome:R-MMU-416993|reactome:R-MMU-5099900|reactome:R-MMU-76005|hgnc:"MGI:97597"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:t4ukCPPAnYUtHCH1hnQE+uiyfEM10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P16054	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N|hgnc:"MGI:97599"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P68404	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-397048|uniprotkb:F2Z441|uniprotkb:P04410|uniprotkb:P04411|uniprotkb:A0JNZ5|intact:EBI-4304045|ensembl:ENSMUSP00000064812	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:kpcb_mouse(display_long)|uniprotkb:Prkcb(gene name)|psi-mi:Prkcb(display_short)|uniprotkb:Pkcb(gene name synonym)|uniprotkb:Prkcb1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_032881.1|refseq:NP_001303601.1|ensembl:ENSMUSG00000052889(gene)|ensembl:ENSMUST00000064921(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006915"(apoptotic process)|go:"GO:0008091"(spectrin)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010827"(regulation of glucose transmembrane transport)|go:"GO:0010829"(negative regulation of glucose transmembrane transport)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030949"(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031526"(brush border membrane)|go:"GO:0035403"("histone kinase activity (H3-T6 specific)")|go:"GO:0035408"(histone H3-T6 phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040008"(regulation of growth)|go:"GO:0042113"(B cell activation)|go:"GO:0042393"(histone binding)|go:"GO:0042493"|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044305"(calyx of Held)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050861"(positive regulation of B cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0071322"(cellular response to carbohydrate stimulus)|go:"GO:0099171"(presynaptic modulation of chemical synaptic transmission)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014375(Protein kinase C, alpha/beta/gamma types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR034664|interpro:IPR035892|mint:P68404|reactome:R-MMU-114516|reactome:R-MMU-1169091|reactome:R-MMU-416993|reactome:R-MMU-4419969|reactome:R-MMU-5099900|reactome:R-MMU-5218921|reactome:R-MMU-5668599|reactome:R-MMU-76005|dip:DIP-31583N|hgnc:"MGI:97596"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:wPR+19jsOpjLky/X5fpkIK5o5SM10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q4VA93	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-911551|ensembl:ENSMUSP00000062392	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:q4va93_mouse(display_long)|uniprotkb:Prkca(gene name)|psi-mi:Prkca(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000050965(gene)|ensembl:ENSMUST00000059595(transcript)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002159"(desmosome assembly)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0031966"(mitochondrial membrane)|refseq:NP_035231.2|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0035403"("histone kinase activity (H3-T6 specific)")|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0090330"(regulation of platelet aggregation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014375(Protein kinase C, alpha/beta/gamma types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR034663|interpro:IPR035892|rcsb pdb:6UWA|hgnc:"MGI:97595"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:Y3paSSKWHeZcmEXDHpDFBuvsbYA10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:H3BK84	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16736098|ensembl:ENSMUSP00000135290	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:h3bk84_mouse(display_long)|uniprotkb:Prkar2b(gene name)|psi-mi:Prkar2b(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|ensembl:ENSMUSG00000002997(gene)|ensembl:ENSMUST00000146865(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0030552"(cAMP binding)|hgnc:"MGI:97760"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:HUWGXPU0v3Zu14HfmDHgip22OsM10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P68181-2	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16736090|ensembl:ENSMUSP00000101743	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:p68181-2(display_long)|uniprotkb:Prkacb(gene name)|psi-mi:Prkacb(display_short)|uniprotkb:Pkacb(gene name synonym)|uniprotkb:Beta2(isoform synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000005034(gene)|ensembl:ENSMUST00000106137(transcript)|intact:EBI-400685(isoform-parent)|hgnc:"MGI:97594"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:Fn64AayHgfDbHCe6bshm3cViLgY10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P05132	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-400564|uniprotkb:Q9JID0|ensembl:ENSMUSP00000005606	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:kapca_mouse(display_long)|uniprotkb:Prkaca(gene name)|psi-mi:Prkaca(display_short)|uniprotkb:Pkaca(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001264827.1|refseq:NP_032880.1|reactome:R-MMU-8963896|reactome:R-MMU-983231|ensembl:ENSMUSG00000005469(gene)|go:"GO:0097546"(ciliary base)|go:"GO:0098793"(presynapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR044109|mint:P05132|ensembl:ENSMUST00000005606(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001843"(neural tube closure)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0036126"(sperm flagellum)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048240"(sperm capacitation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048792"(spontaneous exocytosis of neurotransmitter)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051447"(negative regulation of meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0097225"(sperm midpiece)|rcsb pdb:1APM|rcsb pdb:1ATP|rcsb pdb:1BKX|rcsb pdb:1BX6|rcsb pdb:1FMO|rcsb pdb:1J3H|rcsb pdb:1JBP|rcsb pdb:1JLU|rcsb pdb:1L3R|rcsb pdb:1PVK|rcsb pdb:1RDQ|rcsb pdb:1RE8|rcsb pdb:1REJ|rcsb pdb:1REK|rcsb pdb:1SYK|rcsb pdb:2CPK|rcsb pdb:2ERZ|rcsb pdb:2QCS|rcsb pdb:2QUR|rcsb pdb:2QVS|rcsb pdb:3FHI|rcsb pdb:3FJQ|rcsb pdb:3IDB|rcsb pdb:3IDC|rcsb pdb:3J4Q|rcsb pdb:3J4R|rcsb pdb:3O7L|rcsb pdb:3OW3|rcsb pdb:3PVB|rcsb pdb:3QAL|rcsb pdb:3QAM|rcsb pdb:3TNP|rcsb pdb:3TNQ|rcsb pdb:3X2U|rcsb pdb:3X2V|rcsb pdb:3X2W|rcsb pdb:4DFX|rcsb pdb:4DFY|rcsb pdb:4DFZ|rcsb pdb:4DG0|rcsb pdb:4DG2|rcsb pdb:4DG3|rcsb pdb:4DH1|rcsb pdb:4DH3|rcsb pdb:4DH5|rcsb pdb:4DH7|rcsb pdb:4DH8|rcsb pdb:4DIN|rcsb pdb:4HPT|rcsb pdb:4HPU|rcsb pdb:4IAC|rcsb pdb:4IAD|rcsb pdb:4IAF|rcsb pdb:4IAI|rcsb pdb:4IAK|rcsb pdb:4IAY|rcsb pdb:4IAZ|rcsb pdb:4IB0|rcsb pdb:4IB1|rcsb pdb:4IB3|rcsb pdb:4NTS|rcsb pdb:4NTT|rcsb pdb:4O21|rcsb pdb:4O22|rcsb pdb:4WBB|rcsb pdb:4X6Q|rcsb pdb:4X6R|rcsb pdb:4XW4|rcsb pdb:4XW5|rcsb pdb:4XW6|rcsb pdb:5JR7|rcsb pdb:5X3F|rcsb pdb:6E21|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|rcsb pdb:6MM8|reactome:R-MMU-163615|reactome:R-MMU-164378|reactome:R-MMU-180024|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-381676|reactome:R-MMU-392517|reactome:R-MMU-422356|reactome:R-MMU-432040|reactome:R-MMU-4420097|reactome:R-MMU-442720|reactome:R-MMU-512988|reactome:R-MMU-5578775|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5620912|reactome:R-MMU-5621575|reactome:R-MMU-5687128|reactome:R-MMU-8853659|reactome:R-MMU-8854518|dip:DIP-6086N|hgnc:"MGI:97592"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:HdW51RuiujpUxo0Fu8TbWz3Yk8c10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:E0CZ78	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16736064|ensembl:ENSMUSP00000125630	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:e0cz78_mouse(display_long)|uniprotkb:Ppp3cb(gene name)|psi-mi:Ppp3cb(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000021816(gene)|ensembl:ENSMUST00000161445(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0033192"(calmodulin-dependent protein phosphatase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0097720"(calcineurin-mediated signaling)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR041751|interpro:IPR043360|refseq:NP_001297355.1|hgnc:"MGI:107163"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:JDpFzuv5AJ8hiDbbhkJjDme19gM10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P63328-2	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16736057|ensembl:ENSMUSP00000071040	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:p63328-2(display_long)|uniprotkb:CAM-PRP catalytic subunit(gene name synonym)|uniprotkb:Calmodulin-dependent calcineurin A subunit alpha isoform(gene name synonym)|uniprotkb:Ppp3ca(gene name)|psi-mi:Ppp3ca(display_short)|uniprotkb:Calna(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000028161(gene)|ensembl:ENSMUST00000070198(transcript)|intact:EBI-397208(isoform-parent)|hgnc:"MGI:107164"(identity)	go:"GO:0014069"(postsynaptic density)	-	isoform-comment:No experimental confirmation available.	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:S3MMBrBQ1lWnGBbtzMPBLMiqNTc10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q6R891	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-774681|uniprotkb:Q8K0X7|ensembl:ENSMUSP00000041732	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:neb2_mouse(display_long)|uniprotkb:Neurabin-II(gene name synonym)|uniprotkb:Spinophilin(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 9B(gene name synonym)|uniprotkb:Ppp1r9b(gene name)|psi-mi:Ppp1r9b(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_758465.2|ensembl:ENSMUSG00000038976(gene)|ensembl:ENSMUST00000038696(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003006"(developmental process involved in reproduction)|go:"GO:0003779"(actin binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007568"(aging)|go:"GO:0007612"(learning)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016358"(dendrite development)|go:"GO:0016477"(cell migration)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019900"(kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031175"(neuron projection development)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0034695"(response to prostaglandin E)|go:"GO:0035094"(response to nicotine)|go:"GO:0035690"|go:"GO:0035902"(response to immobilization stress)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051015"(actin filament binding)|go:"GO:0060179"(male mating behavior)|go:"GO:0061458"(reproductive system development)|go:"GO:0071315"(cellular response to morphine)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097338"(response to clozapine)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903119"(protein localization to actin cytoskeleton)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1904372"(positive regulation of protein localization to actin cortical patch)|go:"GO:1904373"(response to kainic acid)|go:"GO:1904386"(response to L-phenylalanine derivative)|go:"GO:1990778"(protein localization to cell periphery)|go:"GO:1990780"(cytoplasmic side of dendritic spine plasma membrane)|go:"GO:2000474"(regulation of opioid receptor signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR029921|interpro:IPR036034|interpro:IPR040645|interpro:IPR043446|mint:Q6R891|hgnc:"MGI:2387581"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:UKGG1FQWWvX56wsI2kQB1jU5uOc10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:H3BL28	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16736035|ensembl:ENSMUSP00000135629	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:h3bl28_mouse(display_long)|uniprotkb:Ppp1r9a(gene name)|psi-mi:Ppp1r9a(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000032827(gene)|ensembl:ENSMUST00000175889(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007015"(actin filament organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031175"(neuron projection development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051823"(regulation of synapse structural plasticity)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0097237"(cellular response to toxic substance)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900272"(negative regulation of long-term synaptic potentiation)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904049"(negative regulation of spontaneous neurotransmitter secretion)|go:"GO:0031594"(neuromuscular junction)|go:"GO:1990761"(growth cone lamellipodium)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029994|interpro:IPR036034|interpro:IPR040645|interpro:IPR043446|hgnc:"MGI:2442401"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:q95QCV/SZFmaf+jxQ83V8b2+zaU10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P62141	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-352338|uniprotkb:P37140|uniprotkb:Q3TBE5|uniprotkb:Q3TL90|uniprotkb:Q542E7|uniprotkb:Q8C285|uniprotkb:Q9DBY2|ensembl:ENSMUSP00000015100|ensembl:ENSMUSP00000144047	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:pp1b_mouse(display_long)|uniprotkb:Ppp1cb(gene name)|psi-mi:Ppp1cb(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_766295.2|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0016791"(phosphatase activity)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0046872"(metal ion binding)|go:"GO:0050115"(myosin-light-chain-phosphatase activity)|go:"GO:0051301"(cell division)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|mint:P62141|reactome:R-MMU-2565942|reactome:R-MMU-5625740|reactome:R-MMU-5627123|reactome:R-MMU-5673000|ensembl:ENSMUSG00000014956(gene)|ensembl:ENSMUST00000015100(transcript)|ensembl:ENSMUST00000201360(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|hgnc:"MGI:104871"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:VtNJVyimeiEuRDDWtGswTqoSOH810090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P62137	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-357187|ensembl:ENSMUSP00000039109|uniprotkb:P08129|uniprotkb:P20653|uniprotkb:P22802|uniprotkb:Q3U7G7|uniprotkb:Q9Z1G2	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:pp1a_mouse(display_long)|uniprotkb:Ppp1ca(gene name)|psi-mi:Ppp1ca(display_short)|uniprotkb:Ppp1a(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0006417"(regulation of translation)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0009987"(cellular process)|go:"GO:0010288"(response to lead ion)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0030324"(lung development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0051301"(cell division)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037979|mint:P62137|rcsb pdb:5ZQV|rcsb pdb:5ZT0|reactome:R-MMU-180024|ensembl:ENSMUSG00000040385(gene)|ensembl:ENSMUST00000046094(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|refseq:NP_114074.1|hgnc:"MGI:103016"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:kr38FkfqhN5ex5rxh4ZJbSdd8IM10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q810U4-2	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16736027|ensembl:ENSMUSP00000106376	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:q810u4-2(display_long)|uniprotkb:Neuronal surface protein Bravo(gene name synonym)|uniprotkb:NgCAM-related cell adhesion molecule(gene name synonym)|uniprotkb:Nrcam(gene name)|psi-mi:Nrcam(display_short)|uniprotkb:Kiaa0343(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	intact:EBI-8321816(isoform-parent)|ensembl:ENSMUSG00000020598(gene)|ensembl:ENSMUST00000110748(transcript)|hgnc:"MGI:104750"(identity)	go:"GO:0014069"(postsynaptic density)	-	isoform-comment:No experimental confirmation available.	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:y4HR1Ijne5YyNZu0A9jMEj/Pdb410090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:B0F2B4	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16735989|uniprotkb:A7LAI9|uniprotkb:B1P942	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:nlgn4_mouse(display_long)|uniprotkb:Neuroligin-4(gene name synonym)|uniprotkb:Nlgn4l(gene name)|psi-mi:Nlgn4l(display_short)|uniprotkb:Nl4*(gene name synonym)|uniprotkb:Nlgn4(gene name synonym)|uniprotkb:Nlgn4x(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0060076"(excitatory synapse)|go:"GO:0071625"(vocalization behavior)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:0097104"(postsynaptic membrane assembly)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098793"(presynapse)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0002124"(territorial aggressive behavior)|go:"GO:0003360"(brainstem development)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007158"(neuron cell-cell adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008049"(male courtship behavior)|go:"GO:0009986"(cell surface)|go:"GO:0021549"(cerebellum development)|go:"GO:0030425"(dendrite)|go:"GO:0035176"(social behavior)|go:"GO:0035265"(organ growth)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0045202"(synapse)|interpro:IPR029058|interpro:IPR002018(Carboxylesterase, type B)|interpro:IPR019819|hgnc:"MGI:3775191"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:mED4FvYQRHJrypfSkrTtKPgLb8g10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:A2AGI3	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16735954|ensembl:ENSMUSP00000113863	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:a2agi3_mouse(display_long)|uniprotkb:Nlgn3(gene name)|psi-mi:Nlgn3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000031302(gene)|ensembl:ENSMUST00000118111(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0045202"(synapse)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050808"(synapse organization)|interpro:IPR000460(Neuroligin)|interpro:IPR002018(Carboxylesterase, type B)|interpro:IPR019819|interpro:IPR029058|interpro:IPR030024|hgnc:"MGI:2444609"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:8SW1PnuMH8mvE9xD2e6msY8oS1c10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:E9QK34	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16735905|ensembl:ENSMUSP00000103944|ensembl:ENSMUSP00000142086	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:e9qk34_mouse(display_long)|uniprotkb:Nlgn1(gene name)|psi-mi:Nlgn1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	go:"GO:0050808"(synapse organization)|go:"GO:0060076"(excitatory synapse)|interpro:IPR000460(Neuroligin)|interpro:IPR002018(Carboxylesterase, type B)|interpro:IPR019819|interpro:IPR029058|interpro:IPR030022|go:"GO:0050804"(modulation of chemical synaptic transmission)|ensembl:ENSMUSG00000063887(gene)|ensembl:ENSMUST00000108308(transcript)|ensembl:ENSMUST00000191835(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0042043"(neurexin family protein binding)|refseq:NP_001156859.1|refseq:XP_006535488.1|hgnc:"MGI:2179435"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:4BoVwvDQpLCiUOsLDryAUKiRSSc10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q04690-2	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16735896|ensembl:ENSMUSP00000103886	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:q04690-2(display_long)|uniprotkb:Neurofibromatosis-related protein NF-1(gene name synonym)|uniprotkb:Nf1(gene name)|psi-mi:Nf1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000020716(gene)|ensembl:ENSMUST00000108251(transcript)|intact:EBI-397326(isoform-parent)|hgnc:"MGI:97306"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:fuDOIDn4zUo2i8/UjdAQZessAyc10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P46935	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-773516|uniprotkb:O08758|uniprotkb:Q3UZI2|uniprotkb:Q8BGB3|ensembl:ENSMUSP00000034740	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:nedd4_mouse(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:Nedd4(gene name)|psi-mi:Nedd4(display_short)|uniprotkb:Kiaa0093(gene name synonym)|uniprotkb:Nedd-4(gene name synonym)|uniprotkb:Nedd4a(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym)|uniprotkb:Nedd4-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_035020.2|dip:DIP-32323N|ensembl:ENSMUSG00000032216(gene)|ensembl:ENSMUST00000034740(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042110"(T cell activation)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0045121"(membrane raft)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46935|rcsb pdb:3M7F|reactome:R-MMU-1169408|reactome:R-MMU-1253288|reactome:R-MMU-8948747|reactome:R-MMU-8948751|reactome:R-MMU-983168|hgnc:"MGI:97297"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:JBCreVF4v92fnTXZN3OH9nlW10A10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P28660	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-771576|uniprotkb:Q3UPY6|uniprotkb:Q80TX0|uniprotkb:Q8CG49|uniprotkb:Q99KY0|ensembl:ENSMUSP00000028386	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:nckp1_mouse(display_long)|uniprotkb:p125Nap1(gene name synonym)|uniprotkb:Membrane-associated protein HEM-2(gene name synonym)|uniprotkb:Brain protein H19(gene name synonym)|uniprotkb:MH19(gene name synonym)|uniprotkb:Nckap1(gene name)|psi-mi:Nckap1(display_short)|uniprotkb:Hem2(gene name synonym)|uniprotkb:Kiaa0587(gene name synonym)|uniprotkb:Nap1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_058661.1|ensembl:ENSMUSG00000027002(gene)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001726"(ruffle)|go:"GO:0001756"(somitogenesis)|go:"GO:0001843"(neural tube closure)|go:"GO:0007354"(zygotic determination of anterior/posterior axis, embryo)|go:"GO:0007492"(endoderm development)|go:"GO:0008078"(mesodermal cell migration)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030903"(notochord development)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031209"(SCAR complex)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031941"(filamentous actin)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0045175"(basal protein localization)|go:"GO:0045176"(apical protein localization)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048340"(paraxial mesoderm morphogenesis)|go:"GO:0048570"(notochord morphogenesis)|go:"GO:0048617"(embryonic foregut morphogenesis)|ensembl:ENSMUST00000028386(transcript)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0098794"(postsynapse)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR019137|mint:P28660|reactome:R-MMU-2029482|reactome:R-MMU-4420097|reactome:R-MMU-5663213|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013423|hgnc:"MGI:1355333"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:NIygMTpuScC4fys7MrAWJD7Hd4M10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:O35136-2	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16735888|ensembl:ENSMUSP00000049390	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:o35136-2(display_long)|uniprotkb:Neural cell adhesion molecule RB-8(gene name synonym)|uniprotkb:R4B12(gene name synonym)|uniprotkb:Ncam2(gene name)|psi-mi:Ncam2(display_short)|uniprotkb:Ocam(gene name synonym)|uniprotkb:Rncam(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	intact:EBI-774970(isoform-parent)|ensembl:ENSMUSG00000022762(gene)|ensembl:ENSMUST00000037785(transcript)|hgnc:"MGI:97282"(identity)	go:"GO:0014069"(postsynaptic density)	-	isoform-comment:Contains a GPI-anchor amidated asparagine at position 703.	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:WROHGOBW+2fUxkn8m42IfSJwJ+k10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q9EPN1-3	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16735879	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:q9epn1-3(display_long)|uniprotkb:Lysosomal-trafficking regulator 2(gene name synonym)|uniprotkb:Nbea(gene name)|psi-mi:Nbea(display_short)|uniprotkb:Lyst2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	intact:EBI-527731(isoform-parent)|hgnc:"MGI:1347075"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:xZv+652lCEfAf6C3mCf6+Uo8tuA10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:F7AMS7	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16735863|ensembl:ENSMUSP00000117959	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:f7ams7_mouse(display_long)|uniprotkb:Mink1(gene name)|psi-mi:Mink1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000020827(gene)|ensembl:ENSMUST00000136663(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001180(Citron-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|hgnc:"MGI:1355329"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:EQc2N1RThOGV/8GKOs9CT+d4NjM10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q63844	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-397682|uniprotkb:Q61531|uniprotkb:Q8K0X5|uniprotkb:Q91YW5|ensembl:ENSMUSP00000051619	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:mk03_mouse(display_long)|uniprotkb:Mapk3(gene name)|psi-mi:Mapk3(display_short)|uniprotkb:Extracellular signal-regulated kinase 1(gene name synonym)|uniprotkb:Insulin-stimulated MAP2 kinase(gene name synonym)|uniprotkb:p44-ERK1(gene name synonym)|uniprotkb:ERT2(gene name synonym)|uniprotkb:MAP kinase isoform p44(gene name synonym)|uniprotkb:Microtubule-associated protein 2 kinase(gene name synonym)|uniprotkb:MNK1(gene name synonym)|uniprotkb:Erk1(gene name synonym)|uniprotkb:Prkm3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_036082.1|dip:DIP-31078N|go:"GO:0007568"(aging)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0014032"(neural crest cell development)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031281"(positive regulation of cyclase activity)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0048538"(thymus development)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051403"(stress-activated MAPK cascade)|ensembl:ENSMUSG00000063065(gene)|ensembl:ENSMUST00000057669(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|reactome:R-MMU-9627069|reactome:R-MMU-982772|go:"GO:0060440"(trachea formation)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000657"(negative regulation of apolipoprotein binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q63844|reactome:R-MMU-110056|reactome:R-MMU-112409|reactome:R-MMU-1169408|reactome:R-MMU-1295596|reactome:R-MMU-162658|reactome:R-MMU-170968|reactome:R-MMU-198753|reactome:R-MMU-202670|reactome:R-MMU-2029482|reactome:R-MMU-2559580|reactome:R-MMU-2559582|reactome:R-MMU-2559585|reactome:R-MMU-2871796|reactome:R-MMU-3371453|reactome:R-MMU-375165|reactome:R-MMU-445144|reactome:R-MMU-450341|reactome:R-MMU-456926|reactome:R-MMU-5654726|reactome:R-MMU-5654727|reactome:R-MMU-5654732|reactome:R-MMU-5654733|reactome:R-MMU-5663213|reactome:R-MMU-5668599|reactome:R-MMU-5673001|reactome:R-MMU-5674135|reactome:R-MMU-5674499|reactome:R-MMU-5675221|reactome:R-MMU-6811558|reactome:R-MMU-73728|reactome:R-MMU-74749|reactome:R-MMU-881907|reactome:R-MMU-8939211|hgnc:"MGI:1346859"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:I2hStA4IjS6t6Ky7fb9zFPOcZag10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q3TQZ7	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16735842|ensembl:ENSMUSP00000108467	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:q3tqz7_mouse(display_long)|uniprotkb:Mapk10(gene name)|psi-mi:Mapk10(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000046709(gene)|ensembl:ENSMUST00000112846(transcript)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008351(JNK MAP kinase)|interpro:IPR011009(Protein kinase-like)|refseq:NP_001305060.1|hgnc:"MGI:1346863"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:hx4vA0c0dlOyhJFnFgb851cDRzw10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P63085	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-397697|uniprotkb:P27703|uniprotkb:Q3V1U6|ensembl:ENSMUSP00000156154|ensembl:ENSMUSP00000065983|ensembl:ENSMUSP00000111396	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:mk01_mouse(display_long)|uniprotkb:Mapk1(gene name)|psi-mi:Mapk1(display_short)|uniprotkb:Erk2(gene name synonym)|uniprotkb:Mapk(gene name synonym)|uniprotkb:Prkm1(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 2(gene name synonym)|uniprotkb:MAP kinase isoform p42(gene name synonym)|uniprotkb:ERT1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001033752.1|refseq:NP_036079.1|refseq:XP_006522210.1|dip:DIP-661N|ensembl:ENSMUST00000069107(transcript)|ensembl:ENSMUST00000115731(transcript)|ensembl:ENSMUST00000232611(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015966"(diadenosine tetraphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019858"(cytosine metabolic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030424"(axon)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035094"(response to nicotine)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043627"(response to estrogen)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046697"(decidualization)|go:"GO:0048538"(thymus development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P63085|reactome:R-MMU-111995|reactome:R-MMU-112409|reactome:R-MMU-112411|reactome:R-MMU-1295596|reactome:R-MMU-162658|reactome:R-MMU-170968|reactome:R-MMU-198753|reactome:R-MMU-202670|reactome:R-MMU-2029482|reactome:R-MMU-2559580|reactome:R-MMU-2559582|reactome:R-MMU-2559585|reactome:R-MMU-2871796|reactome:R-MMU-3371453|reactome:R-MMU-375165|reactome:R-MMU-437239|reactome:R-MMU-445144|reactome:R-MMU-450341|reactome:R-MMU-456926|reactome:R-MMU-5654726|reactome:R-MMU-5654727|reactome:R-MMU-5654732|reactome:R-MMU-5654733|reactome:R-MMU-5663213|reactome:R-MMU-5668599|reactome:R-MMU-5673001|reactome:R-MMU-5674135|reactome:R-MMU-5674499|reactome:R-MMU-5675221|reactome:R-MMU-6798695|reactome:R-MMU-6811558|reactome:R-MMU-74749|reactome:R-MMU-881907|reactome:R-MMU-8939211|reactome:R-MMU-9627069|reactome:R-MMU-9634635|ensembl:ENSMUSG00000063358(gene)|reactome:R-MMU-9634638|reactome:R-MMU-982772|hgnc:"MGI:1346858"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:4STZhl2O+Ilh0lj8wQp8y2vVehA10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P31938	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-298860|ensembl:ENSMUSP00000005066	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:mp2k1_mouse(display_long)|uniprotkb:Map2k1(gene name)|psi-mi:Map2k1(display_short)|uniprotkb:Mek1(gene name synonym)|uniprotkb:Prkmk1(gene name synonym)|uniprotkb:ERK activator kinase 1(gene name synonym)|uniprotkb:MAPK/ERK kinase 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000004936(gene)|ensembl:ENSMUST00000005066(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003056"(regulation of vascular associated smooth muscle contraction)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021697"(cerebellar cortex formation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043204"(perikaryon)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032402"(melanosome transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034111"(negative regulation of homotypic cell-cell adhesion)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048313"(Golgi inheritance)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048538"(thymus development)|go:"GO:0048678"(response to axon injury)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0060502"(epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0060711"(labyrinthine layer development)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0090398"(cellular senescence)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-MMU-110056|reactome:R-MMU-170968|reactome:R-MMU-445144|reactome:R-MMU-5673000|reactome:R-MMU-5674135|reactome:R-MMU-5674499|refseq:NP_032953.1|dip:DIP-467N|hgnc:"MGI:1346866"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:OOj1juW9l4rnEH/W3CjXWZFKMvw10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q80TE7	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-774900	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:lrrc7_mouse(display_long)|uniprotkb:Protein LAP1(gene name synonym)|uniprotkb:Densin-180(gene name synonym)|uniprotkb:Lrrc7(gene name)|psi-mi:Lrrc7(display_short)|uniprotkb:Kiaa1365(gene name synonym)|uniprotkb:Lap1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001278381.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR032675|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR036034|reactome:R-MMU-438066|reactome:R-MMU-5673001|reactome:R-MMU-6798695|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0030175"(filopodium)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043194"(axon initial segment)|go:"GO:0043197"(dendritic spine)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|hgnc:"MGI:2676665"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:QWCdfe/eQM/ZaaAG2GwZi+Rf87Q10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:A2CG49	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865|hgnc:"MGI:2685385"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q3TES0	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16725408|ensembl:ENSMUSP00000038653|uniprotkb:Q3UHP8|uniprotkb:Q80TJ8	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:iqec3_mouse(display_long)|uniprotkb:Iqsec3(gene name)|psi-mi:Iqsec3(display_short)|uniprotkb:Kiaa1110(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000040797(gene)|ensembl:ENSMUST00000046373(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050808"(synapse organization)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099629"(postsynaptic specialization of symmetric synapse)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000904(SEC7-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR033742|interpro:IPR035999|go:"GO:0060077"(inhibitory synapse)|refseq:NP_001028526.1|hgnc:"MGI:2677208"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:ca8BfkMISVCn8R1jxdoGGFCJd3s10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q5DU25	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-773452|uniprotkb:E9QK46	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:iqec2_mouse(display_long)|uniprotkb:Iqsec2(gene name)|psi-mi:Iqsec2(display_short)|uniprotkb:Kiaa0522(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR000904(SEC7-like)|interpro:IPR023394|interpro:IPR033742|refseq:XP_006528908.1|interpro:IPR035999|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|hgnc:"MGI:3528396"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:D2kDV/pgwPkXPHcK5+7S9+HS6Wk10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q8R0S2	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-772277|uniprotkb:Q3TZC3|uniprotkb:Q5DU15|ensembl:ENSMUSP00000098712	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:iqec1_mouse(display_long)|uniprotkb:Iqsec1(gene name)|psi-mi:Iqsec1(display_short)|uniprotkb:Kiaa0763(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001127855.1|ensembl:ENSMUSG00000034312(gene)|ensembl:ENSMUST00000101153(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008289"(lipid binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0060996"(dendritic spine development)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000904(SEC7-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR030737|interpro:IPR033742|interpro:IPR035999|hgnc:"MGI:1196356"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:BZg7CaLndE4ak8KXs34YFf9iBRQ10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q3UQ44	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16724715|ensembl:ENSMUSP00000067685	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:iqga2_mouse(display_long)|uniprotkb:Iqgap2(gene name)|psi-mi:Iqgap2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000021676(gene)|ensembl:ENSMUST00000068603(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005902"(microvillus)|go:"GO:0009986"(cell surface)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0070493"(thrombin-activated receptor signaling pathway)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR036872|reactome:R-MMU-5626467|reactome:R-MMU-6798695|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013408|refseq:NP_081987.1|hgnc:"MGI:2449975"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:YD6GurtWVrIzYEBzXb7fdJ6qAWI10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q9JKF1	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-644633|ensembl:ENSMUSP00000128278|uniprotkb:G3UW45	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:iqga1_mouse(display_long)|uniprotkb:Iqgap1(gene name)|psi-mi:Iqgap1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900086"(positive regulation of peptidyl-tyrosine autophosphorylation)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990776"(response to angiotensin)|ensembl:ENSMUSG00000030536(gene)|ensembl:ENSMUST00000167377(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010761"(fibroblast migration)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035305"(negative regulation of dephosphorylation)|go:"GO:0036057"(slit diaphragm)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0031252"(cell leading edge)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR027417|interpro:IPR036872|mint:Q9JKF1|reactome:R-MMU-373753|reactome:R-MMU-5626467|reactome:R-MMU-5674135|reactome:R-MMU-6798695|reactome:R-MMU-8980692|reactome:R-MMU-9013106|reactome:R-MMU-9013148|go:"GO:1990904"(ribonucleoprotein complex)|reactome:R-MMU-9013149|refseq:NP_057930.2|reactome:R-MMU-9013404|reactome:R-MMU-9013406|reactome:R-MMU-9013420|reactome:R-MMU-9013424|hgnc:"MGI:1352757"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:qjWT+er4GkLOlebk3zzRHh2Iqoo10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:E9Q4F9	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16735820|ensembl:ENSMUSP00000095931	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:e9q4f9_mouse(display_long)|uniprotkb:Homer2(gene name)|psi-mi:Homer2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000025813(gene)|ensembl:ENSMUST00000098326(transcript)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_001157559.1|refseq:XP_006540972.1|hgnc:"MGI:1347354"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:HkWcbVZ7SSaQKKvheZiH5jW7EAQ10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q9Z2Y3	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-396980|uniprotkb:Q8K3E1|uniprotkb:Q8K4M8|uniprotkb:Q9Z0E9|uniprotkb:Q9Z216|ensembl:ENSMUSP00000079026	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:home1_mouse(display_long)|uniprotkb:Homer1(gene name)|psi-mi:Homer1(display_short)|uniprotkb:Vesl1(gene name synonym)|uniprotkb:VASP/Ena-related gene up-regulated during seizure and LTP 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_036112.1|refseq:NP_671705.2|refseq:NP_687036.1|refseq:NP_001271118.1|refseq:NP_001334527.1|ensembl:ENSMUSG00000007617(gene)|ensembl:ENSMUST00000080127(transcript)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044309"(neuron spine)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048875"(chemical homeostasis within a tissue)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098794"(postsynapse)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099186"(structural constituent of postsynapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:2001256"(regulation of store-operated calcium entry)|go:"GO:2001257"(regulation of cation channel activity)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9Z2Y3|reactome:R-MMU-6794361|hgnc:"MGI:1347345"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:aOI1ZRXwOjFH9a3s6Jf1FNfMdiA10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P13020-2	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-1018662|ensembl:ENSMUSP00000144561	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:p13020-2(display_long)|uniprotkb:Cytoplasmic(isoform synonym)|uniprotkb:Gsn(gene name)|psi-mi:Gsn(display_short)|uniprotkb:Gsb(gene name synonym)|uniprotkb:Actin-depolymerizing factor(gene name synonym)|uniprotkb:Brevin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	intact:EBI-445180(gels_mouse)|ensembl:ENSMUSG00000026879(gene)|ensembl:ENSMUST00000201185(transcript)|uniprotkb:P13020-2(isoform-parent)|hgnc:"MGI:95851"(identity)	go:"GO:0014069"(postsynaptic density)	-	isoform-comment:Initiator Met-1 is removed or contains a N-acetylmethionine at position 1.	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:b2sFogvdReqPivH+VZllUBkVGA010090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q9WV60	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-400793|ensembl:ENSMUSP00000023507	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:gsk3b_mouse(display_long)|uniprotkb:Gsk3b(gene name)|psi-mi:Gsk3b(display_short)|uniprotkb:Serine/threonine-protein kinase GSK3B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_062801.1|dip:DIP-32446N|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006983"(ER overload response)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0007520"(myoblast fusion)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010822"(positive regulation of mitochondrion organization)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014043"(negative regulation of neuron maturation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0034452"(dynactin binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|go:"GO:2000738"(positive regulation of stem cell differentiation)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033573|interpro:IPR039192|mint:Q9WV60|rcsb pdb:4NU1|rcsb pdb:5AIR|rcsb pdb:6AE3|reactome:R-MMU-195253|reactome:R-MMU-196299|reactome:R-MMU-3371453|reactome:R-MMU-399956|reactome:R-MMU-4641262|reactome:R-MMU-5250924|reactome:R-MMU-5610785|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035733"(hepatic stellate cell activation)|go:"GO:0036016"(cellular response to interleukin-3)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043227"(membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044027"(hypermethylation of CpG island)|go:"GO:0044297"(cell body)|go:"GO:0045121"(membrane raft)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046849"(bone remodeling)|go:"GO:0048156"(tau protein binding)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071109"(superior temporal gyrus development)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090290"(positive regulation of osteoclast proliferation)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099159"(regulation of modification of postsynaptic structure)|go:"GO:0106027"(neuron projection organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0150101"(regulation of microtubule anchoring at centrosome)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1901030"(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901984"(negative regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1904339"(negative regulation of dopaminergic neuron differentiation)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904780"(negative regulation of protein localization to centrosome)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000171"(negative regulation of dendrite development)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|ensembl:ENSMUSG00000022812(gene)|ensembl:ENSMUST00000023507(transcript)|go:"GO:0000320"(re-entry into mitotic cell cycle)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|hgnc:"MGI:1861437"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:FKe0WkOBBYU0vIJLmcFNMJ+KVHA10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:E9QMC2	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16735783|ensembl:ENSMUSP00000102884|ensembl:ENSMUSP00000118393|uniprotkb:F6WSV0	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:e9qmc2_mouse(display_long)|uniprotkb:Grm5(gene name)|psi-mi:Grm5(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000049583(gene)|ensembl:ENSMUST00000107263(transcript)|ensembl:ENSMUST00000125009(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000162(GPCR, family 3, metabotropic glutamate receptor)|interpro:IPR000202(GPCR, family 3, metabotropic glutamate receptor 5)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR011500(GPCR, family 3, nine cysteines region)|interpro:IPR017978|interpro:IPR017979|interpro:IPR019588|interpro:IPR028082|interpro:IPR038550|refseq:NP_001074883.1|hgnc:"MGI:1351342"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:j/j52EhyJy0J9a9bTS5JNjb3sbE10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q9QYS2	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-770623|uniprotkb:Q14DJ9|ensembl:ENSMUSP00000004076	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:grm3_mouse(display_long)|uniprotkb:Gprc1c(gene name synonym)|uniprotkb:Mglur3(gene name synonym)|uniprotkb:Grm3(gene name)|psi-mi:Grm3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_862898.1|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0010467"(gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030424"(axon)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0001641"(group II metabotropic glutamate receptor activity)|ensembl:ENSMUSG00000003974(gene)|ensembl:ENSMUST00000004076(transcript)|go:"GO:0001640"(adenylate cyclase inhibiting G protein-coupled glutamate receptor activity)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097449"(astrocyte projection)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR000162(GPCR, family 3, metabotropic glutamate receptor)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001234(GPCR, family 3, metabotropic glutamate receptor 3)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR011500(GPCR, family 3, nine cysteines region)|interpro:IPR017978|interpro:IPR017979|interpro:IPR028082|interpro:IPR038550|mint:Q9QYS2|reactome:R-MMU-418594|reactome:R-MMU-420499|hgnc:"MGI:1351340"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:6YCf0CVHHO8OR8GpAMxCucRLxJE10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q14BI2	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-5281533|ensembl:ENSMUSP00000023959	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:grm2_mouse(display_long)|uniprotkb:Grm2(gene name)|psi-mi:Grm2(display_short)|uniprotkb:Gprc1b(gene name synonym)|uniprotkb:Mglur2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001153825.1|ensembl:ENSMUSG00000023192(gene)|ensembl:ENSMUST00000023959(transcript)|go:"GO:0001640"(adenylate cyclase inhibiting G protein-coupled glutamate receptor activity)|go:"GO:0001641"(group II metabotropic glutamate receptor activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0010467"(gene expression)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014048"(regulation of glutamate secretion)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0042220"(response to cocaine)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0090461"(glutamate homeostasis)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:2001023"(regulation of response to drug)|interpro:IPR000162(GPCR, family 3, metabotropic glutamate receptor)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001458(GPCR, family 3, metabotropic glutamate receptor 2)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR011500(GPCR, family 3, nine cysteines region)|interpro:IPR017978|interpro:IPR017979|interpro:IPR028082|interpro:IPR038550|mint:Q14BI2|reactome:R-MMU-418594|reactome:R-MMU-420499|hgnc:"MGI:1351339"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:51Vq4ZsTylhat6thFK/8MBMIKUI10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P97772-2	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16735774|ensembl:ENSMUSP00000101189|ensembl:ENSMUSP00000101190	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:p97772-2(display_long)|uniprotkb:Grm1(gene name)|psi-mi:Grm1(display_short)|uniprotkb:Gprc1a(gene name synonym)|uniprotkb:Mglur1(gene name synonym)|uniprotkb:B(isoform synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000019828(gene)|ensembl:ENSMUST00000105560(transcript)|ensembl:ENSMUST00000105561(transcript)|intact:EBI-396863(isoform-parent)|hgnc:"MGI:1351338"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:1AnW/xX5Ls3SY/6SG4wRSD0ywuU10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q01097	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-400125|uniprotkb:Q9DCB2	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:nmde2_mouse(display_long)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-2(gene name synonym)|uniprotkb:Grin2b(gene name)|psi-mi:Grin2b(display_short)|uniprotkb:N-methyl D-aspartate receptor subtype 2B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_032197.3|go:"GO:0001508"(action potential)|go:"GO:0001662"(behavioral fear response)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001964"(startle response)|go:"GO:0001967"(suckling behavior)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005234"(extracellularly glutamate-gated ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007423"(sensory organ development)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008306"(associative learning)|go:"GO:0009986"(cell surface)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016594"(glycine binding)|go:"GO:0016595"(glutamate binding)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0030018"(Z disc)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0036094"(small molecule binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0042596"(fear response)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043113"(receptor clustering)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0044307"(dendritic branch)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0046960"(sensitization)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0048511"(rhythmic process)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099529"(neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential)|go:"GO:0099583"(neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|go:"GO:0099566"(regulation of postsynaptic cytosolic calcium ion concentration)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018884|interpro:IPR019594|interpro:IPR028082|reactome:R-MMU-3928662|reactome:R-MMU-438066|reactome:R-MMU-5673001|reactome:R-MMU-8849932|reactome:R-MMU-9609736|mint:Q01097|dip:DIP-31568N|hgnc:"MGI:95821"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:SvjoNuuHCFT+Yj1woYrEvU6n8B010090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P35436	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-400115|ensembl:ENSMUSP00000032331|ensembl:ENSMUSP00000111501|ensembl:ENSMUSP00000142900	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:nmde1_mouse(display_long)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-1(gene name synonym)|uniprotkb:Grin2a(gene name)|psi-mi:Grin2a(display_short)|uniprotkb:N-methyl D-aspartate receptor subtype 2A(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_032196.2|reactome:R-MMU-8849932|reactome:R-MMU-9609736|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099507"(ligand-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:1903539"(protein localization to postsynaptic membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018884|interpro:IPR019594|interpro:IPR028082|reactome:R-MMU-438066|go:"GO:0098839"(postsynaptic density membrane)|ensembl:ENSMUSG00000059003(gene)|ensembl:ENSMUST00000032331(transcript)|ensembl:ENSMUST00000115835(transcript)|ensembl:ENSMUST00000199708(transcript)|go:"GO:0001508"(action potential)|go:"GO:0001964"(startle response)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0030431"(sleep)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0033058"(directional locomotion)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040011"(locomotion)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042428"(serotonin metabolic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048511"(rhythmic process)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|refseq:XP_006521857.1|dip:DIP-31567N|hgnc:"MGI:95820"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:5DMFDOh6NuFArDtKp2gp2IpmhWQ10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P35438	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-400084|uniprotkb:Q8CFS4|uniprotkb:A2AI15|uniprotkb:A2AI18|ensembl:ENSMUSP00000028335	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:nmdz1_mouse(display_long)|uniprotkb:Glutamate [NMDA] receptor subunit zeta-1(gene name synonym)|uniprotkb:Grin1(gene name)|psi-mi:Grin1(display_short)|uniprotkb:Glurz1(gene name synonym)|uniprotkb:N-methyl-D-aspartate receptor subunit NR1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001171127.1|refseq:NP_001171128.1|refseq:NP_032195.1|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0032590"(dendrite membrane)|go:"GO:0035176"(social behavior)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043278"(response to morphine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043576"(regulation of respiratory gaseous exchange)|go:"GO:0044307"(dendritic branch)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0021586"(pons maturation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048511"(rhythmic process)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0060076"(excitatory synapse)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0060179"(male mating behavior)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099507"(ligand-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:1900149"(positive regulation of Schwann cell migration)|go:"GO:1902952"(positive regulation of dendritic spine maintenance)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903539"(protein localization to postsynaptic membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:0030425"(dendrite)|go:"GO:1905429"(response to glycine)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|go:"GO:0030426"(growth cone)|interpro:IPR018882|interpro:IPR019594|interpro:IPR028082|mint:P35438|reactome:R-MMU-3928662|reactome:R-MMU-438066|reactome:R-MMU-5673001|reactome:R-MMU-8849932|reactome:R-MMU-9609736|ensembl:ENSMUSG00000026959(gene)|ensembl:ENSMUST00000028335(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001661"(conditioned taste aversion)|go:"GO:0001964"(startle response)|go:"GO:0001967"(suckling behavior)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007616"(long-term memory)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008306"(associative learning)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008355"(olfactory learning)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0010646"(regulation of cell communication)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016594"(glycine binding)|go:"GO:0016595"(glutamate binding)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0018964"(propylene metabolic process)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019899"(enzyme binding)|go:"GO:0019902"(phosphatase binding)|dip:DIP-31577N|hgnc:"MGI:95819"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:JEUDmVL8TNipn1XuGBwsBsu9ofU10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P23819	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-77538|uniprotkb:Q61604|uniprotkb:Q61605|uniprotkb:Q8BG69|uniprotkb:Q8BXU3|uniprotkb:Q9D6D3	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:gria2_mouse(display_long)|uniprotkb:Gria2(gene name)|psi-mi:Gria2(display_short)|uniprotkb:Glur2(gene name synonym)|uniprotkb:GluR-B(gene name synonym)|uniprotkb:GluR-K2(gene name synonym)|uniprotkb:Glutamate receptor ionotropic, AMPA 2(gene name synonym)|uniprotkb:AMPA-selective glutamate receptor 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051117"(ATPase binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099544"(perisynaptic space)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|reactome:R-MMU-399710|reactome:R-MMU-416993|reactome:R-MMU-438066|go:"GO:0000149"(SNARE binding)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004971"(AMPA glutamate receptor activity)|go:"GO:0005234"(extracellularly glutamate-gated ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0015277"(kainate selective glutamate receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031623"(receptor internalization)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|interpro:IPR028082|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|mint:P23819|hgnc:"MGI:95809"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:v71xzThz9kadLOPBasVAc1y/FXs10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:F6YNQ1	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16735742|ensembl:ENSMUSP00000117746	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:f6ynq1_mouse(display_long)|uniprotkb:Gria1(gene name)|psi-mi:Gria1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	go:"GO:0045211"(postsynaptic membrane)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000020524(gene)|ensembl:ENSMUST00000151045(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0016021"(integral component of membrane)|refseq:NP_001239332.1|refseq:XP_006532297.1|hgnc:"MGI:95808"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:2JzvrrWO300DWSAu8fQ3un/XRRo10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P62880	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-356951|uniprotkb:P11016|uniprotkb:P54312|ensembl:ENSMUSP00000031726|ensembl:ENSMUSP00000129353	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:gbb2_mouse(display_long)|uniprotkb:Gnb2(gene name)|psi-mi:Gnb2(display_short)|uniprotkb:Transducin beta chain 2(gene name synonym)|uniprotkb:G protein subunit beta-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_034442.1|refseq:XP_006504616.1|ensembl:ENSMUSG00000029713(gene)|ensembl:ENSMUST00000031726(transcript)|ensembl:ENSMUST00000150063(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043209"(myelin sheath)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051020"(GTPase binding)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P62880|reactome:R-MMU-1296041|reactome:R-MMU-202040|reactome:R-MMU-381676|reactome:R-MMU-392170|reactome:R-MMU-392451|reactome:R-MMU-392851|reactome:R-MMU-400042|reactome:R-MMU-4086398|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-418217|reactome:R-MMU-418555|reactome:R-MMU-418592|reactome:R-MMU-418594|reactome:R-MMU-418597|reactome:R-MMU-420092|reactome:R-MMU-428930|reactome:R-MMU-432040|reactome:R-MMU-456926|reactome:R-MMU-500657|reactome:R-MMU-6814122|reactome:R-MMU-8964315|reactome:R-MMU-8964616|reactome:R-MMU-9009391|reactome:R-MMU-997272|hgnc:"MGI:95784"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:dingPUxdpAhe7UMLquv0eqXNtUM10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P62874	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-357152|ensembl:ENSMUSP00000030940|ensembl:ENSMUSP00000101241|ensembl:ENSMUSP00000130123|ensembl:ENSMUSP00000135091|uniprotkb:P04901|uniprotkb:P04697	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:gbb1_mouse(display_long)|uniprotkb:Gnb1(gene name)|psi-mi:Gnb1(display_short)|uniprotkb:Transducin beta chain 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000029064(gene)|ensembl:ENSMUST00000030940(transcript)|ensembl:ENSMUST00000105616(transcript)|ensembl:ENSMUST00000165335(transcript)|ensembl:ENSMUST00000176637(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007603"(phototransduction, visible light)|reactome:R-MMU-9009391|reactome:R-MMU-997272|reactome:R-MMU-8964616|go:"GO:0010659"(cardiac muscle cell apoptotic process)|go:"GO:0030425"(dendrite)|go:"GO:0008283"(cell population proliferation)|go:"GO:0030507"(spectrin binding)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0042622"(photoreceptor outer segment membrane)|go:"GO:0043209"(myelin sheath)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047391"(alkylglycerophosphoethanolamine phosphodiesterase activity)|go:"GO:0050909"(sensory perception of taste)|go:"GO:0051020"(GTPase binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P62874|rcsb pdb:6K41|rcsb pdb:6K42|rcsb pdb:6RMV|reactome:R-MMU-1296041|reactome:R-MMU-202040|reactome:R-MMU-2485179|reactome:R-MMU-381676|reactome:R-MMU-381753|reactome:R-MMU-392170|reactome:R-MMU-392451|reactome:R-MMU-392851|reactome:R-MMU-400042|reactome:R-MMU-4086398|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-418217|reactome:R-MMU-418555|reactome:R-MMU-418592|reactome:R-MMU-418594|reactome:R-MMU-418597|reactome:R-MMU-420092|reactome:R-MMU-428930|reactome:R-MMU-432040|reactome:R-MMU-456926|reactome:R-MMU-500657|reactome:R-MMU-6814122|reactome:R-MMU-8964315|refseq:NP_001153488.1|refseq:NP_001153489.1|refseq:NP_032168.1|refseq:XP_017175466.1|hgnc:"MGI:95781"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:zP/G70MXiSQpzbyyWFTWrJFQENk10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:O70443	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-771994|uniprotkb:O70442|uniprotkb:Q61637|uniprotkb:Q91WM4|ensembl:ENSMUSP00000036087|ensembl:ENSMUSP00000124639	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:gnaz_mouse(display_long)|uniprotkb:"G(x) alpha chain"(gene name synonym)|uniprotkb:Gz-alpha(gene name synonym)|uniprotkb:Gnaz(gene name)|psi-mi:Gnaz(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_034441.1|refseq:XP_006513299.1|refseq:XP_006513300.1|refseq:XP_006513298.1|ensembl:ENSMUSG00000040009(gene)|ensembl:ENSMUST00000037813(transcript)|ensembl:ENSMUST00000159991(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|go:"GO:0044297"(cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0098664"(G protein-coupled serotonin receptor signaling pathway)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:O70443|reactome:R-MMU-418597|hgnc:"MGI:95780"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:tIlKib9CoNSvCkb2TvLU/QwdCYk10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P63094-2	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16735734|ensembl:ENSMUSP00000104713	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:p63094-2(display_long)|uniprotkb:Adenylate cyclase-stimulating G alpha protein(gene name synonym)|uniprotkb:Gnas(gene name)|psi-mi:Gnas(display_short)|uniprotkb:Gnas1(gene name synonym)|uniprotkb:MNCb-5546(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000027523(gene)|ensembl:ENSMUST00000109085(transcript)|intact:EBI-444709(isoform-parent)|hgnc:"MGI:95777"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:ulzhJCkFKuk6kfFAB/JlrwYDSdM10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P21279	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-771975|uniprotkb:Q6PFF5|ensembl:ENSMUSP00000025541	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:gnaq_mouse(display_long)|uniprotkb:Guanine nucleotide-binding protein alpha-q(gene name synonym)|uniprotkb:Gnaq(gene name)|psi-mi:Gnaq(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_032165.3|dip:DIP-606N|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045634"(regulation of melanocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0047391"(alkylglycerophosphoethanolamine phosphodiesterase activity)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|interpro:IPR000654(G-protein alpha subunit, group Q)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P21279|rcsb pdb:2BCJ|rcsb pdb:2RGN|rcsb pdb:3AH8|rcsb pdb:3OHM|rcsb pdb:4EKC|rcsb pdb:4EKD|rcsb pdb:4GNK|rcsb pdb:4QJ3|rcsb pdb:4QJ4|rcsb pdb:4QJ5|rcsb pdb:5DO9|reactome:R-MMU-112043|reactome:R-MMU-202040|reactome:R-MMU-399997|reactome:R-MMU-416476|reactome:R-MMU-418592|reactome:R-MMU-428930|reactome:R-MMU-434316|reactome:R-MMU-456926|reactome:R-MMU-6814122|go:"GO:0044297"(cell body)|ensembl:ENSMUSG00000024639(gene)|ensembl:ENSMUST00000025541(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001508"(action potential)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016020"(membrane)|go:"GO:0016322"(neuron remodeling)|go:"GO:0021884"(forebrain neuron development)|go:"GO:0030425"(dendrite)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031826"(type 2A serotonin receptor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042711"(maternal behavior)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043267"(negative regulation of potassium ion transport)|hgnc:"MGI:95776"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:7HfYjIynxSexMzn1uUS6x4sfzbI10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P18872	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-771950|uniprotkb:P18873|intact:EBI-1018769|ensembl:ENSMUSP00000034198|ensembl:ENSMUSP00000114144	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:gnao_mouse(display_long)|uniprotkb:Gnao1(gene name)|psi-mi:Gnao1(display_short)|uniprotkb:Gna0(gene name synonym)|uniprotkb:Gnao(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001106855.1|refseq:NP_034438.1|dip:DIP-29921N|ensembl:ENSMUSG00000031748(gene)|ensembl:ENSMUST00000034198(transcript)|ensembl:ENSMUST00000125716(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0007568"(aging)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0009987"(cellular process)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030900"(forebrain development)|go:"GO:0031175"(neuron projection development)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034097"(response to cytokine)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043005"(neuron projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0043278"(response to morphine)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044297"(cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0051430"(corticotropin-releasing hormone receptor 1 binding)|go:"GO:0051926"(negative regulation of calcium ion transport)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P18872|rcsb pdb:3C7K|reactome:R-MMU-4086398|hgnc:"MGI:95775"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:CCww9l5owYxGicswRXjsSu6Y+5g10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:B2RSH2	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-2308910|ensembl:ENSMUSP00000074259	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:gnai1_mouse(display_long)|uniprotkb:Gnai1(gene name)|psi-mi:Gnai1(display_short)|uniprotkb:Gnai-1(gene name synonym)|uniprotkb:Adenylate cyclase-inhibiting G alpha protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_034435.1|ensembl:ENSMUSG00000057614(gene)|ensembl:ENSMUST00000074694(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045121"(membrane raft)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0099738"(cell cortex region)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-MMU-170670|reactome:R-MMU-392170|reactome:R-MMU-400042|reactome:R-MMU-418594|reactome:R-MMU-9009391|hgnc:"MGI:95771"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:3yQOCXJb8Undp/Xw42xrBiG5ePE10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P27601	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-2255627|uniprotkb:Q6PF99|ensembl:ENSMUSP00000020930	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:gna13_mouse(display_long)|uniprotkb:Gna-13(gene name synonym)|uniprotkb:Gna13(gene name)|psi-mi:Gna13(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_034433.3|dip:DIP-46241N|ensembl:ENSMUSG00000020611(gene)|ensembl:ENSMUST00000020930(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030154"(cell differentiation)|go:"GO:0030168"(platelet activation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031526"(brush border membrane)|go:"GO:0031584"(activation of phospholipase D activity)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031752"(D5 dopamine receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0046872"(metal ion binding)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|interpro:IPR000469(G-protein alpha subunit, group 12)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P27601|rcsb pdb:1SHZ|rcsb pdb:1ZCB|rcsb pdb:3AB3|rcsb pdb:3CX6|rcsb pdb:3CX7|rcsb pdb:3CX8|reactome:R-MMU-193648|reactome:R-MMU-416482|reactome:R-MMU-428930|reactome:R-MMU-456926|reactome:R-MMU-9013148|reactome:R-MMU-9013149|hgnc:"MGI:95768"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:lG592gVBa3xiDv+BVn5SF8Rj/pA10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q5F258	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16735713|ensembl:ENSMUSP00000098375	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:q5f258_mouse(display_long)|uniprotkb:Git1(gene name)|psi-mi:Git1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000011877(gene)|ensembl:ENSMUST00000100812(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR002110(Ankyrin)|interpro:IPR013724("Spa2 homology (SHD) of GIT")|interpro:IPR020683|interpro:IPR022018|interpro:IPR032352|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|refseq:XP_006533012.1|hgnc:"MGI:1927140"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:w9oRo1556FC2b4vWr5xT7wnG+wI10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q61598-2	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16735706|ensembl:ENSMUSP00000062996	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:q61598-2(display_long)|uniprotkb:GDI-3(gene name synonym)|uniprotkb:Guanosine diphosphate dissociation inhibitor 2(gene name synonym)|uniprotkb:Gdi2(gene name)|psi-mi:Gdi2(display_short)|uniprotkb:Gdi3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000021218(gene)|ensembl:ENSMUST00000059515(transcript)|intact:EBI-6665490(isoform-parent)|hgnc:"MGI:99845"(identity)	go:"GO:0014069"(postsynaptic density)	-	isoform-comment:No experimental confirmation available.	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:MVAXD9eA/N8upczxZjORnl6J9wU10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:O70318	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-643339|uniprotkb:G3X9B8|ensembl:ENSMUSP00000055122|ensembl:ENSMUSP00000090314	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:e41l2_mouse(display_long)|uniprotkb:Generally expressed protein 4.1(gene name synonym)|uniprotkb:Epb41l2(gene name)|psi-mi:Epb41l2(display_short)|uniprotkb:Epb4.1l2(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 4.1-like 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_038539.2|refseq:NP_001186194.1|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0005654"(nucleoplasm)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030507"(spectrin binding)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0042731"(PH domain binding)|go:"GO:0051301"(cell division)|go:"GO:0099738"(cell cortex region)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR007477(SAB)|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030546|interpro:IPR035963|mint:O70318|reactome:R-MMU-6794361|ensembl:ENSMUSG00000019978(gene)|ensembl:ENSMUST00000053748(transcript)|ensembl:ENSMUST00000092645(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|hgnc:"MGI:103009"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:4hNttT3WQk43puSMmOdjpNS8oUo10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q9Z2H5	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-774482|uniprotkb:Q3U3L1|uniprotkb:Q3UHP7|uniprotkb:Q80U34|uniprotkb:Q8K204	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:e41l1_mouse(display_long)|uniprotkb:Neuronal protein 4.1(gene name synonym)|uniprotkb:Epb41l1(gene name)|psi-mi:Epb41l1(display_short)|uniprotkb:Epb4(gene name synonym)|uniprotkb:Epb4.1l1(gene name synonym)|uniprotkb:Kiaa0338(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 4.1-like 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001278049.1|refseq:NP_001278051.1|refseq:NP_001278052.1|refseq:NP_001006665.1|refseq:NP_038538.1|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR019749|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019747|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR018979|interpro:IPR018980|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR007477(SAB)|interpro:IPR029071|interpro:IPR035963|mint:Q9Z2H5|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0097060"(synaptic membrane)|reactome:R-MMU-399719|reactome:R-MMU-6794361|hgnc:"MGI:103010�"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:Lu31NnWhI356njHUtKbBlaO6nWE10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:B7ZNS2	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16735693|ensembl:ENSMUSP00000105196	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:b7zns2_mouse(display_long)|uniprotkb:Dlgap4(gene name)|psi-mi:Dlgap4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000061689(gene)|ensembl:ENSMUST00000109568(transcript)|go:"GO:0023052"(signaling)|interpro:IPR005026(Guanylate-kinase-associated protein)|interpro:IPR030527|refseq:NP_001264116.1|hgnc:"MGI:2138865"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:+4kulkwvpW65phqOvGL6dBgZoW010090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:B1AS06	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16735681|ensembl:ENSMUSP00000101698	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:b1as06_mouse(display_long)|uniprotkb:Dlgap3(gene name)|psi-mi:Dlgap3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000042388(gene)|ensembl:ENSMUST00000106092(transcript)|go:"GO:0023052"(signaling)|interpro:IPR005026(Guanylate-kinase-associated protein)|interpro:IPR030526|refseq:XP_006503167.1|hgnc:"MGI:3039563"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:bIEDbBzjulDcrYVDgPsjiNsH7i010090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q8BJ42	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-2308675|uniprotkb:Q6XBF3|ensembl:ENSMUSP00000039647|ensembl:ENSMUSP00000119613	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:dlgp2_mouse(display_long)|uniprotkb:Dlgap2(gene name)|psi-mi:Dlgap2(display_short)|uniprotkb:Dap2(gene name synonym)|uniprotkb:SAP90/PSD-95-associated protein 2(gene name synonym)|uniprotkb:PSD-95/SAP90-binding protein 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001139437.1|refseq:NP_766498.2|refseq:XP_017168275.1|ensembl:ENSMUSG00000047495(gene)|ensembl:ENSMUST00000043279(transcript)|ensembl:ENSMUST00000133298(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099572"(postsynaptic specialization)|interpro:IPR005026(Guanylate-kinase-associated protein)|interpro:IPR030525|reactome:R-MMU-6794361|hgnc:"MGI:2443181"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:9V3GlRM3AupA70mmFtZ4biXuC9E10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q9D415-4	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16735672	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:q9d415-4(display_long)|uniprotkb:Guanylate kinase-associated protein(gene name synonym)|uniprotkb:PSD-95/SAP90-binding protein 1(gene name synonym)|uniprotkb:SAP90/PSD-95-associated protein 1(gene name synonym)|uniprotkb:GKAP1b(isoform synonym)|uniprotkb:Dlgap1(gene name)|psi-mi:Dlgap1(display_short)|uniprotkb:Gkap(gene name synonym)|uniprotkb:Kiaa4162(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	intact:EBI-400152(isoform-parent)|hgnc:"MGI:1346065"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:XXkdKfkj/SHgYk0L+MqRgTMz3Fs10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q62108	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-300895|ensembl:ENSMUSP00000104229|uniprotkb:Q5NCV5|uniprotkb:Q5NCV6|uniprotkb:Q5NCV7|uniprotkb:Q91WJ1	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:dlg4_mouse(display_long)|uniprotkb:Dlg4(gene name)|psi-mi:Dlg4(display_short)|uniprotkb:Dlgh4(gene name synonym)|uniprotkb:Psd95(gene name synonym)|uniprotkb:Postsynaptic density protein 95(gene name synonym)|uniprotkb:Synapse-associated protein 90(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000020886(gene)|ensembl:ENSMUST00000108588(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0019894"(kinesin binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031812"(P2Y1 nucleotide receptor binding)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0035176"(social behavior)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071625"(vocalization behavior)|go:"GO:0071944"(cell periphery)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097109"(neuroligin family protein binding)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|go:"GO:0060076"(excitatory synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|mint:Q62108|reactome:R-MMU-399719|reactome:R-MMU-438066|reactome:R-MMU-451308|reactome:R-MMU-5625900|reactome:R-MMU-5673001|reactome:R-MMU-5682910|reactome:R-MMU-6794361|reactome:R-MMU-8849932|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|refseq:NP_001103222.1|refseq:NP_031890.1|dip:DIP-29888N|hgnc:"MGI:1277959"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:9Ylvs2goE8Z/6ff4AqFCEKrPanY10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q52KF7	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-2308659|ensembl:ENSMUSP00000000901	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:q52kf7_mouse(display_long)|uniprotkb:Dlg3(gene name)|psi-mi:Dlg3(display_short)|uniprotkb:Dlgh3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001277331.1|ensembl:ENSMUSG00000000881(gene)|ensembl:ENSMUST00000000901(transcript)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR035763|interpro:IPR036028|interpro:IPR036034|hgnc:"MGI:1888986"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:hyfICTZYOd5AE1HBQw0oXDF9ru810090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:D3YUZ8	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16735652|ensembl:ENSMUSP00000102811	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:d3yuz8_mouse(display_long)|uniprotkb:Dlg2(gene name)|psi-mi:Dlg2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000052572(gene)|ensembl:ENSMUST00000107193(transcript)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR020590|interpro:IPR027417|interpro:IPR035759|interpro:IPR036028|interpro:IPR036034|refseq:XP_011240088.1|hgnc:"MGI:1344351"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:l75t0K9lZXF8GxdnUETWqjFGFQs10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:F6UDT8	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16735639|ensembl:ENSMUSP00000115954	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:f6udt8_mouse(display_long)|uniprotkb:Dlg1(gene name)|psi-mi:Dlg1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000022770(gene)|ensembl:ENSMUST00000131136(transcript)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR019583|interpro:IPR036028|interpro:IPR036034|hgnc:"MGI:107231"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:5rMiUdMDWj24HVPrnCcd9McY9QI10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q9QXS6	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-445208|uniprotkb:A2CG16|uniprotkb:Q3V234|uniprotkb:Q922X1|uniprotkb:Q9QXS5|ensembl:ENSMUSP00000021950	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:dreb_mouse(display_long)|uniprotkb:Developmentally-regulated brain protein(gene name synonym)|uniprotkb:Dbn1(gene name)|psi-mi:Dbn1(display_short)|uniprotkb:Drba(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001170842.1|refseq:NP_001170843.1|refseq:NP_062787.2|ensembl:ENSMUSG00000034675(gene)|ensembl:ENSMUST00000021950(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005921"(gap junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0010643"(cell communication by chemical coupling)|go:"GO:0010644"(cell communication by electrical coupling)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032507"(maintenance of protein location in cell)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044308"(axonal spine)|go:"GO:0044309"(neuron spine)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048699"(generation of neurons)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090327"(negative regulation of locomotion involved in locomotory behavior)|go:"GO:0098828"(modulation of inhibitory postsynaptic potential)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0120080"(obsolete negative regulation of microfilament motor activity)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902685"(positive regulation of receptor localization to synapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:1902897"(regulation of postsynaptic density protein 95 clustering)|go:"GO:1904113"(negative regulation of muscle filament sliding)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR028438|interpro:IPR029006|mint:Q9QXS6|reactome:R-MMU-9013405|reactome:R-MMU-9013407|reactome:R-MMU-9013418|reactome:R-MMU-9013422|hgnc:"MGI:1931838"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:ArZUGZNIUfSwoIketPcPCXlSM8410090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:F6QQP6	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16735620|ensembl:ENSMUSP00000121506	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:f6qqp6_mouse(display_long)|uniprotkb:Dab2ip(gene name)|psi-mi:Dab2ip(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000026883(gene)|ensembl:ENSMUST00000156669(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043087"(regulation of GTPase activity)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR021887|interpro:IPR023152|interpro:IPR030403|interpro:IPR039360|hgnc:"MGI:1916851"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:/7gN6McnRgZHmSFed1ql2s2XeeU10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q5SQX6	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-773783|uniprotkb:Q3UH21|uniprotkb:Q3UHS8|uniprotkb:Q8BSW0|uniprotkb:Q8CHA9|uniprotkb:Q924D3|uniprotkb:Q9R181|ensembl:ENSMUSP00000090853|ensembl:ENSMUSP00000090854|ensembl:ENSMUSP00000127586	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:cyfp2_mouse(display_long)|uniprotkb:p53-inducible protein 121(gene name synonym)|uniprotkb:Cyfip2(gene name)|psi-mi:Cyfip2(display_short)|uniprotkb:Kiaa1168(gene name synonym)|uniprotkb:Pir121(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_598530.2|refseq:NP_001239388.1|refseq:NP_001239389.1|dip:DIP-32111N|ensembl:ENSMUSG00000020340(gene)|ensembl:ENSMUST00000093165(transcript)|ensembl:ENSMUST00000093166(transcript)|ensembl:ENSMUST00000165599(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031209"(SCAR complex)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051388"(positive regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0097484"(dendrite extension)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR008081(Cytoplasmic FMR1-interacting)|interpro:IPR009828(Protein of unknown function DUF1394)|reactome:R-MMU-2029482|reactome:R-MMU-4420097|reactome:R-MMU-5663213|reactome:R-MMU-9013149|hgnc:"MGI:1924134"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:NP2S3AEcTj9DHTiDHEVM51b8jrE10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q7TMB8	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-772928|uniprotkb:Q3U7Q7|uniprotkb:Q5DU50|uniprotkb:Q7TSZ5|uniprotkb:Q80VN6|uniprotkb:Q8CE85|uniprotkb:Q99LY1|uniprotkb:O88558|ensembl:ENSMUSP00000032629|ensembl:ENSMUSP00000127717	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:cyfp1_mouse(display_long)|uniprotkb:Cyfip1(gene name)|psi-mi:Cyfip1(display_short)|uniprotkb:Shyc(gene name synonym)|uniprotkb:Kiaa0068(gene name synonym)|uniprotkb:Sra1(gene name synonym)|uniprotkb:Specifically Rac1-associated protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001158134.1|refseq:NP_035500.2|refseq:NP_001158133.1|refseq:XP_006540792.1|ensembl:ENSMUSG00000030447(gene)|ensembl:ENSMUST00000032629(transcript)|ensembl:ENSMUST00000163845(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0007411"(axon guidance)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031175"(neuron projection development)|go:"GO:0031209"(SCAR complex)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031529"(ruffle organization)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032433"(filopodium tip)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045202"(synapse)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050890"(cognition)|go:"GO:0051015"(actin filament binding)|go:"GO:0051388"(positive regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0060076"(excitatory synapse)|go:"GO:0090724"(central region of growth cone)|go:"GO:0090725"(peripheral region of growth cone)|go:"GO:0097484"(dendrite extension)|go:"GO:0098794"(postsynapse)|go:"GO:0099563"(modification of synaptic structure)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900029"(positive regulation of ruffle assembly)|go:"GO:1903422"(negative regulation of synaptic vesicle recycling)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR008081(Cytoplasmic FMR1-interacting)|interpro:IPR009828(Protein of unknown function DUF1394)|mint:Q7TMB8|reactome:R-MMU-2029482|reactome:R-MMU-4420097|reactome:R-MMU-5663213|reactome:R-MMU-6798695|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013408|reactome:R-MMU-9013423|hgnc:"MGI:1338801"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:u8cObqx85DIdhPYtV2YWyOao3KE10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q80YA9-2	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16735613	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:q80ya9-2(display_long)|uniprotkb:Cnksr2(gene name)|psi-mi:Cnksr2(display_short)|uniprotkb:Kiaa0902(gene name synonym)|uniprotkb:CNK homolog protein 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	intact:EBI-771429(isoform-parent)|hgnc:"MGI:2661175"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:npQ8kx+1+lc3qlZWDdj/vczGq6810090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q923T9	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-771638|uniprotkb:Q3U3H3|uniprotkb:Q8VED3|ensembl:ENSMUSP00000071720	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:kcc2g_mouse(display_long)|uniprotkb:Camk2g(gene name)|psi-mi:Camk2g(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001034227.1|refseq:NP_001034228.1|refseq:NP_848712.2|ensembl:ENSMUSG00000021820(gene)|ensembl:ENSMUST00000071816(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030154"(cell differentiation)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901897"(regulation of relaxation of cardiac muscle)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|mint:Q923T9|reactome:R-MMU-3371571|reactome:R-MMU-399719|reactome:R-MMU-438066|reactome:R-MMU-5576892|reactome:R-MMU-5578775|reactome:R-MMU-5673000|reactome:R-MMU-5673001|reactome:R-MMU-877300|reactome:R-MMU-936837|hgnc:"MGI:88259"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:pbJqcEUQJQRnAwcKozmS72n9s1w10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q6PHZ2	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-2308458|uniprotkb:Q3UF87|uniprotkb:Q3UQH9|uniprotkb:Q5DTK4|uniprotkb:Q8CAC5|uniprotkb:Q9CZE2|ensembl:ENSMUSP00000143504	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:kcc2d_mouse(display_long)|uniprotkb:Camk2d(gene name)|psi-mi:Camk2d(display_short)|uniprotkb:Kiaa4163(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001020609.1|refseq:NP_076302.1|refseq:NP_001020610.1|refseq:NP_001280592.1|refseq:NP_001280593.1|dip:DIP-47638N|ensembl:ENSMUSG00000053819(gene)|ensembl:ENSMUST00000199300(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0014704"(intercalated disc)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0031432"(titin binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043194"(axon initial segment)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0098901"(regulation of cardiac muscle cell action potential)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901897"(regulation of relaxation of cardiac muscle)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:1902514"(regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|mint:Q6PHZ2|rcsb pdb:6BAB|reactome:R-MMU-3371571|reactome:R-MMU-399719|reactome:R-MMU-438066|reactome:R-MMU-5576892|reactome:R-MMU-5578775|reactome:R-MMU-5673000|reactome:R-MMU-5673001|reactome:R-MMU-877300|reactome:R-MMU-936837|hgnc:"MGI:1341265"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:z2mz73Kq9gwpKgo2Todn0IxQpSI10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:B2RQ57	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16735518|ensembl:ENSMUSP00000126181	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:b2rq57_mouse(display_long)|uniprotkb:Abl2(gene name)|psi-mi:Abl2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000026596(gene)|ensembl:ENSMUST00000166172(transcript)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015015(F-actin binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035837|interpro:IPR036028|interpro:IPR036860|refseq:NP_001129576.1|refseq:NP_033725.2|hgnc:"MGI:87860"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:URPtAtFDeJDeTiOLVkQTCsDQ3FU10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P28652	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-397029|uniprotkb:Q5SVH9|ensembl:ENSMUSP00000105438|ensembl:ENSMUSP00000105440	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:kcc2b_mouse(display_long)|uniprotkb:Camk2b(gene name)|psi-mi:Camk2b(display_short)|uniprotkb:Camk2d(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_031621.3|ensembl:ENSMUSG00000057897(gene)|ensembl:ENSMUST00000109813(transcript)|ensembl:ENSMUST00000109815(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030425"(dendrite)|go:"GO:0032222"(regulation of synaptic transmission, cholinergic)|go:"GO:0032430"(positive regulation of phospholipase A2 activity)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0002030"(inhibitory G protein-coupled receptor phosphorylation)|go:"GO:0043274"(phospholipase binding)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051233"(spindle midzone)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060466"(activation of meiosis involved in egg activation)|reactome:R-MMU-438066|reactome:R-MMU-5576892|reactome:R-MMU-5578775|reactome:R-MMU-5673000|reactome:R-MMU-5673001|reactome:R-MMU-877300|reactome:R-MMU-936837|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:2001222"(regulation of neuron migration)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|mint:P28652|reactome:R-MMU-3371571|reactome:R-MMU-399719|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|dip:DIP-31582N|hgnc:"MGI:88257"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:di/l1bhtPhzeKpErP6iyQfFypBo10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P11798	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-400384|uniprotkb:Q61284|uniprotkb:Q6ZWN4|ensembl:ENSMUSP00000099952	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:kcc2a_mouse(display_long)|uniprotkb:Camk2a(gene name)|psi-mi:Camk2a(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_033922.1|refseq:NP_803126.1|refseq:NP_001273738.1|ensembl:ENSMUSG00000024617(gene)|ensembl:ENSMUST00000102888(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060996"(dendritic spine development)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099004"(calmodulin dependent kinase signaling pathway)|go:"GO:0099148"(regulation of synaptic vesicle docking)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099573"(glutamatergic postsynaptic density)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990443"(peptidyl-threonine autophosphorylation)|go:"GO:2000124"(regulation of endocannabinoid signaling pathway)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|mint:P11798|rcsb pdb:1HKX|rcsb pdb:4X3I|rcsb pdb:6TS3|reactome:R-MMU-3371571|reactome:R-MMU-399719|reactome:R-MMU-4086398|reactome:R-MMU-438066|reactome:R-MMU-5576892|reactome:R-MMU-5578775|reactome:R-MMU-5673000|reactome:R-MMU-5673001|reactome:R-MMU-877300|reactome:R-MMU-936837|dip:DIP-31593N|hgnc:"MGI:88256"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:mHdSlhGhe3sMOyO+YGwROtGOGfY10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:E9QK20	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16735593|ensembl:ENSMUSP00000004214	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:e9qk20_mouse(display_long)|uniprotkb:Cacna1e(gene name)|psi-mi:Cacna1e(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000004110(gene)|ensembl:ENSMUST00000004214(transcript)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0034765"(regulation of ion transmembrane transport)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005449(Voltage-dependent calcium channel, R-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|hgnc:"MGI:106217"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:1knFTF3Whiez6M1eYVXUL0vhr+U10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q6P9R4-2	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16735586	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:q6p9r4-2(display_long)|uniprotkb:Arhgef18(gene name)|psi-mi:Arhgef18(display_short)|uniprotkb:Kiaa0521(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	intact:EBI-6271853(isoform-parent)|hgnc:"MGI:2142567"(identity)	go:"GO:0014069"(postsynaptic density)	-	isoform-comment:No experimental confirmation available.	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:X1ZKVcLMWVRnpgvsbu6Q+OQMNn810090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P59281-2	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16735577|ensembl:ENSMUSP00000158984	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:p59281-2(display_long)|uniprotkb:Arhgap39(gene name)|psi-mi:Arhgap39(display_short)|uniprotkb:D15Wsu169e(gene name synonym)|uniprotkb:Kiaa1688(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	intact:EBI-772284(isoform-parent)|ensembl:ENSMUSG00000033697(gene)|ensembl:ENSMUST00000239134(transcript)|hgnc:"MGI:107858"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:xxFSkacr9YHzYICJc/WOPs3s7Zk10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q8K3H0	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-400377|uniprotkb:Q3UJP7|uniprotkb:Q69ZJ9|uniprotkb:Q8BWZ8|uniprotkb:Q8VCJ8|uniprotkb:Q9CUW4|ensembl:ENSMUSP00000042875	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:dp13a_mouse(display_long)|uniprotkb:Appl1(gene name)|psi-mi:Appl1(display_short)|uniprotkb:Dip13a(gene name synonym)|uniprotkb:Kiaa1428(gene name synonym)|uniprotkb:Adapter protein containing PH domain, PTB domain and leucine zipper motif 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_660256.1|ensembl:ENSMUSG00000040760(gene)|ensembl:ENSMUST00000036570(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0023052"(signaling)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905303"(positive regulation of macropinocytosis)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR037929|mint:Q8K3H0|reactome:R-MMU-418889|hgnc:"MGI:1920243"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:1ZML/W0Qi+jMAeZQ7PXfiHA6YBE10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P17426	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-775189|ensembl:ENSMUSP00000082519|ensembl:ENSMUSP00000127842	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:ap2a1_mouse(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-1(gene name synonym)|uniprotkb:Alpha1-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit(gene name synonym)|uniprotkb:Alpha-adaptin A(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-A large chain(gene name synonym)|uniprotkb:100 kDa coated vesicle protein A(gene name synonym)|uniprotkb:Ap2a1(gene name)|psi-mi:Ap2a1(display_short)|uniprotkb:Adtaa(gene name synonym)|uniprotkb:Clapa1(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001070732.1|refseq:NP_031484.1|ensembl:ENSMUSG00000060279(gene)|ensembl:ENSMUST00000085399(transcript)|ensembl:ENSMUST00000166972(transcript)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0032433"(filopodium tip)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|mint:P17426|reactome:R-MMU-177504|reactome:R-MMU-2132295|reactome:R-MMU-416993|reactome:R-MMU-437239|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8866427|reactome:R-MMU-8964038|hgnc:"MGI:101921"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:Dd6Q+Et/LTlmo5qpro2Zaeq0dMc10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q5SVG5	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16735551|ensembl:ENSMUSP00000105523	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:q5svg5_mouse(display_long)|uniprotkb:Ap1b1(gene name)|psi-mi:Ap1b1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000009090(gene)|ensembl:ENSMUST00000109897(transcript)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030276"(clathrin binding)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013037(Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|interpro:IPR032682|hgnc:"MGI:1096368"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:ax1zFnM+xtWV5UbOgb99OBzZSGI10090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:G5E8K5-3	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16735544|ensembl:ENSMUSP00000061698	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:g5e8k5-3(display_long)|uniprotkb:Ankyrin-G(gene name synonym)|uniprotkb:Ank3(gene name)|psi-mi:Ank3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16736255|imex:IM-26370-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000069601(gene)|ensembl:ENSMUST00000054167(transcript)|intact:EBI-457262(isoform-parent)|hgnc:"MGI:88026"(identity)	go:"GO:0014069"(postsynaptic density)	-	isoform-comment:Contains a phosphoserine at position 830.	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2021/02/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:RSWnU+EPep5P48UGQk3tVtqbPM410090	rigid:5ON/741Cs2Pk+HNH45DpH1CLU/o	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:Q8C008	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-8317102|uniprotkb:Q8C060|intact:MINT-4113786|uniprotkb:A2AN93|ensembl:ENSMUSP00000080643	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:dzan1_mouse(display_long)|uniprotkb:Dzank1(gene name)|psi-mi:Dzank1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	refseq:NP_766447.2|ensembl:ENSMUSG00000037259(gene)|ensembl:ENSMUST00000081982(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR025874|interpro:IPR026876|interpro:IPR036770|mint:Q8C008|hgnc:"MGI:2139080"(identity)	go:"GO:0014069"(postsynaptic density)	-	comment:mint	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:ozGQu95/TVKGDwRgLlTCq+bl3PM10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:Q0KL02-3	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-16736247	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:q0kl02-3(display_long)|uniprotkb:Trio(gene name)|psi-mi:Trio(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	intact:EBI-16725543(isoform-parent)|hgnc:"MGI:1927230"(identity)	go:"GO:0014069"(postsynaptic density)	-	isoform-comment:No experimental confirmation available.	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:qbxBZT0BUNqZOG52EvFv7I4bxGw10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:Q8CC35-3	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-16737024	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:q8cc35-3(display_long)|uniprotkb:Synpo(gene name)|psi-mi:Synpo(display_short)|uniprotkb:Kiaa1029(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	uniprotkb:Q8CC35-3(isoform-parent)|hgnc:"MGI:1099446"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:NdnMlue+wHS84FEuHFLBi0QkNgE10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:F6SEU4	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-5797569|ensembl:ENSMUSP00000141686	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442|hgnc:"MGI:3039785"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:Q62261	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-397843|ensembl:ENSMUSP00000006629|ensembl:ENSMUSP00000011877|uniprotkb:A2AFU1|uniprotkb:Q3TEM7|uniprotkb:Q5SQL8|uniprotkb:Q5SQL9|uniprotkb:Q9QWJ7	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:sptb2_mouse(display_long)|uniprotkb:Sptbn1(gene name)|psi-mi:Sptbn1(display_short)|uniprotkb:Spnb-2(gene name synonym)|uniprotkb:Spnb2(gene name synonym)|uniprotkb:Sptb2(gene name synonym)|uniprotkb:Beta-II spectrin(gene name synonym)|uniprotkb:Fodrin beta chain(gene name synonym)|uniprotkb:Embryonic liver fodrin(gene name synonym)|uniprotkb:Elf(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	ensembl:ENSMUSG00000020315(gene)|ensembl:ENSMUST00000006629(transcript)|ensembl:ENSMUST00000011877(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008091"(spectrin)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030673"(axolemma)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031430"(M band)|go:"GO:0032437"(cuticular plate)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0071709"(membrane assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|interpro:IPR041681|mint:Q62261|rcsb pdb:1BTN|rcsb pdb:1MPH|rcsb pdb:6M3P|reactome:R-MMU-375165|reactome:R-MMU-445095|reactome:R-MMU-5673001|reactome:R-MMU-6807878|reactome:R-MMU-9013420|reactome:R-MMU-9013424|refseq:NP_033286.2|refseq:NP_787030.2|refseq:XP_006514662.1|refseq:XP_006514663.1|dip:DIP-31558N|hgnc:"MGI:98388"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:N6xVFU+ocY6PXsIz5ZIsA05bGPs10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:P16546-2	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-9072039|ensembl:ENSMUSP00000047792	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:p16546-2(display_long)|uniprotkb:Sptan1(gene name)|psi-mi:Sptan1(display_short)|uniprotkb:Alpha-II spectrin(gene name synonym)|uniprotkb:Fodrin alpha chain(gene name synonym)|uniprotkb:Spna2(gene name synonym)|uniprotkb:Spta2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	intact:EBI-911063(isoform-parent)|uniprotkb:P16546-2(isoform-parent)|ensembl:ENSMUSG00000057738(gene)|ensembl:ENSMUST00000046257(transcript)|hgnc:"MGI:98386"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:YaoZBEGmzIXuZ40o+Pq5A2nSHm410090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:Q68FG2	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-2255511|ensembl:ENSMUSP00000008991	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:q68fg2_mouse(display_long)|uniprotkb:Sptbn2(gene name)|psi-mi:Sptbn2(display_short)|uniprotkb:Spnb3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	refseq:NP_067262.1|refseq:XP_006531767.1|refseq:XP_006531768.1|ensembl:ENSMUSG00000067889(gene)|ensembl:ENSMUST00000008991(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007416"(synapse assembly)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008091"(spectrin)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0021692"(cerebellar Purkinje cell layer morphogenesis)|go:"GO:0030534"(adult behavior)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051693"(actin filament capping)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098918"(structural constituent of synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|go:"GO:0099189"(postsynaptic spectrin-associated cytoskeleton)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|interpro:IPR041681|reactome:R-MMU-2132295|reactome:R-MMU-375165|reactome:R-MMU-445095|reactome:R-MMU-5673001|reactome:R-MMU-6807878|hgnc:"MGI:1313261"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:2F7U0dl21KxXpc9Z2sk7D/wzQvM10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:Q2KN98	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-11707802|uniprotkb:Q8CHF9|ensembl:ENSMUSP00000151322	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:cytsa_mouse(display_long)|uniprotkb:Specc1l(gene name)|psi-mi:Specc1l(display_short)|uniprotkb:Cytsa(gene name synonym)|uniprotkb:Kiaa0376(gene name synonym)|uniprotkb:SPECC1-like protein(gene name synonym)|uniprotkb:Sperm antigen with calponin homology and coiled-coil domains 1-like(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	refseq:NP_001139298.1|refseq:NP_700455.3|refseq:XP_006514315.1|refseq:XP_011241891.1|interpro:IPR040166|interpro:IPR036872|ensembl:ENSMUSG00000033444(gene)|ensembl:ENSMUST00000218766(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005921"(gap junction)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030835"(negative regulation of actin filament depolymerization)|go:"GO:0031941"(filamentous actin)|go:"GO:0034332"(adherens junction organization)|go:"GO:0036032"(neural crest cell delamination)|go:"GO:0051301"(cell division)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060325"(face morphogenesis)|go:"GO:0061713"(anterior neural tube closure)|interpro:IPR001715(Calponin-like actin-binding)|refseq:XP_017169616.1|hgnc:"MGI:1921642"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:RkKLF9bYPTd1OMWh1ozpZm4E13410090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:Q62417-5	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-16737016	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:q62417-5(display_long)|uniprotkb:Ponsin(gene name synonym)|uniprotkb:SH3 domain protein 5(gene name synonym)|uniprotkb:SH3P12(gene name synonym)|uniprotkb:c-Cbl-associated protein(gene name synonym)|uniprotkb:Sorbs1(gene name)|psi-mi:Sorbs1(display_short)|uniprotkb:Kiaa1296(gene name synonym)|uniprotkb:Sh3d5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	intact:EBI-2365368(isoform-parent)|hgnc:"MGI:700014"(identity)	go:"GO:0014069"(postsynaptic density)	-	isoform-comment:Contains a phosphoserine at position 164. Contains a phosphoserine at position 346.	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:WEuPoB6/NjOHcwImkaDWk+9e1Mw10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:A2AQ25-9	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-16737008	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:a2aq25-9(display_long)|uniprotkb:Enhancer trap locus 4(gene name synonym)|uniprotkb:Skt(gene name)|psi-mi:Skt(display_short)|uniprotkb:Etl4(gene name synonym)|uniprotkb:Kiaa1217(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	intact:EBI-8821027(isoform-parent)|hgnc:"MGI:98314"(identity)	go:"GO:0014069"(postsynaptic density)	-	isoform-comment:No experimental confirmation available.	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:NfxMKPdZjTHqNgkRZsvJSCuwaLM10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:Q8C0T5-2	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-16737000|ensembl:ENSMUSP00000152356	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:q8c0t5-2(display_long)|uniprotkb:Sipa1l1(gene name)|psi-mi:Sipa1l1(display_short)|uniprotkb:Kiaa0440(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	intact:EBI-8334367(isoform-parent)|ensembl:ENSMUSG00000042700(gene)|ensembl:ENSMUST00000222298(transcript)|hgnc:"MGI:2443679"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:rKZAc8eQTL+l1kbvtX79UARkGUY10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:F6T9T6	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-16736991|ensembl:ENSMUSP00000112405	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:f6t9t6_mouse(display_long)|uniprotkb:Shisa7(gene name)|psi-mi:Shisa7(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	ensembl:ENSMUSG00000053550(gene)|ensembl:ENSMUST00000117452(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR026910|hgnc:"MGI:3605641"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:YHcF9AXxFquoBLxmKAHDbUnEhRk10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:Q4ACU6	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-771450|uniprotkb:Q69ZD8|intact:EBI-8401154|intact:MINT-4130064|uniprotkb:F8S0X0|uniprotkb:F8S0X2|uniprotkb:F8S0X3|uniprotkb:F8S0X5|uniprotkb:F8S0X6|uniprotkb:Q9JJZ3|uniprotkb:S6BMD3|uniprotkb:S6CCV8|ensembl:ENSMUSP00000104932	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:shan3_mouse(display_long)|uniprotkb:Proline-rich synapse-associated protein 2(gene name synonym)|uniprotkb:SPANK-2(gene name synonym)|uniprotkb:Shank3(gene name)|psi-mi:Shank3(display_short)|uniprotkb:Kiaa1650(gene name synonym)|uniprotkb:Prosap2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	refseq:NP_067398.2|dip:DIP-32262N|ensembl:ENSMUSG00000022623(gene)|ensembl:ENSMUST00000109309(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001838"(embryonic epithelial tube formation)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007416"(synapse assembly)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0021773"(striatal medium spiny neuron differentiation)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030534"(adult behavior)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0051835"(positive regulation of synapse structural plasticity)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097107"(postsynaptic density assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097114"(NMDA glutamate receptor clustering)|go:"GO:0097117"(guanylate kinase-associated protein clustering)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035640"(exploration behavior)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0040011"(locomotion)|go:"GO:0042297"(vocal learning)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043621"(protein self-association)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045794"(negative regulation of cell volume)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048170"(positive regulation of long-term neuronal synaptic plasticity)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1900451"(positive regulation of glutamate receptor signaling pathway)|go:"GO:1900452"(regulation of long-term synaptic depression)|go:"GO:1904717"(regulation of AMPA glutamate receptor clustering)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|go:"GO:2000822"(regulation of behavioral fear response)|go:"GO:2000969"(positive regulation of AMPA receptor activity)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|mint:Q4ACU6|rcsb pdb:3O5N|rcsb pdb:5IZU|rcsb pdb:6KYH|rcsb pdb:6KYK|reactome:R-MMU-6794361|reactome:R-MMU-8853659|hgnc:"MGI:1930016"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:40CZZZ4qetQSv6a6gsUMVeL0c+o10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:Q80UK0	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-646282|uniprotkb:Q3TLJ1|uniprotkb:Q810W3|uniprotkb:Q8CI09|ensembl:ENSMUSP00000099720|ensembl:ENSMUSP00000099721	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:sesd1_mouse(display_long)|uniprotkb:Sestd1(gene name)|psi-mi:Sestd1(display_short)|uniprotkb:Huntingtin-interacting protein-like protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	refseq:NP_780674.1|refseq:XP_006499263.1|refseq:XP_006499264.1|refseq:XP_006499265.1|ensembl:ENSMUSG00000042272(gene)|ensembl:ENSMUST00000102659(transcript)|ensembl:ENSMUST00000102660(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1904878"(negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|hgnc:"MGI:1916262"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:6vT+co7M/u3no7+pSYJLpvahLEA10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:Q9EQZ6-3	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-15566495|ensembl:ENSMUSP00000099759	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:q9eqz6-3(display_long)|uniprotkb:Rapgef4(gene name)|psi-mi:Rapgef4(display_short)|uniprotkb:Cgef2(gene name synonym)|uniprotkb:Epac2(gene name synonym)|uniprotkb:Exchange factor directly activated by cAMP 2(gene name synonym)|uniprotkb:Exchange protein directly activated by cAMP 2(gene name synonym)|uniprotkb:cAMP-dependent Rap1 guanine-nucleotide exchange factor(gene name synonym)|uniprotkb:cAMP-regulated guanine nucleotide exchange factor II(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	intact:EBI-772212(isoform-parent)|uniprotkb:Q9EQZ6-3(isoform-parent)|ensembl:ENSMUSG00000049044(gene)|ensembl:ENSMUST00000102698(transcript)|hgnc:"MGI:1917723"(identity)	go:"GO:0014069"(postsynaptic density)	-	isoform-comment:Produced by alternative splicing of isoform 1. No experimental confirmation available.	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:Xrtmy52Pe6YX8C1AGp1Doutu5xc10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:H3BJA6	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-16736972|ensembl:ENSMUSP00000134909	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:h3bja6_mouse(display_long)|uniprotkb:Ppp1r9a(gene name)|psi-mi:Ppp1r9a(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|ensembl:ENSMUSG00000032827(gene)|ensembl:ENSMUST00000176729(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007015"(actin filament organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0030027"(lamellipodium)|go:"GO:0051823"(regulation of synapse structural plasticity)|go:"GO:0030175"(filopodium)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0030425"(dendrite)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0097237"(cellular response to toxic substance)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0030426"(growth cone)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031175"(neuron projection development)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:1900272"(negative regulation of long-term synaptic potentiation)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904049"(negative regulation of spontaneous neurotransmitter secretion)|go:"GO:1990761"(growth cone lamellipodium)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR029994|interpro:IPR036034|interpro:IPR040645|interpro:IPR043446|hgnc:"MGI:2442401"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:InPRdbX2daHHyxTR1mdE5XGDSBc10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:Q68FH0-3	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-16736965	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:q68fh0-3(display_long)|uniprotkb:Armadillo-related protein(gene name synonym)|uniprotkb:Pkp4(gene name)|psi-mi:Pkp4(display_short)|uniprotkb:Armrp(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	intact:EBI-16728261(isoform-parent)|hgnc:"MGI:109281"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:S0LZJRt1m2KlGp6FT9F7ZuFyXng10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:Q01063-2	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-16736958|ensembl:ENSMUSP00000073742	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:q01063-2(display_long)|uniprotkb:DPDE3(gene name synonym)|uniprotkb:PDE4D9(isoform synonym)|uniprotkb:Pde4d(gene name)|psi-mi:Pde4d(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	ensembl:ENSMUSG00000021699(gene)|ensembl:ENSMUST00000074103(transcript)|intact:EBI-7764239(isoform-parent)|hgnc:"MGI:99555"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:EyGq7Es9lcrwCNKH5ONmx9i6HxQ10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:P08553	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-445188|uniprotkb:A2VCT5|uniprotkb:Q0VDM8|uniprotkb:Q3HRJ6|uniprotkb:Q3TNS4|uniprotkb:Q3TPK2|uniprotkb:Q61961|uniprotkb:Q8BQ20	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:nfm_mouse(display_long)|uniprotkb:Neurofilament triplet M protein(gene name synonym)|uniprotkb:160 kDa neurofilament protein(gene name synonym)|uniprotkb:Neurofilament 3(gene name synonym)|uniprotkb:Nefm(gene name)|psi-mi:Nefm(display_short)|uniprotkb:Nef3(gene name synonym)|uniprotkb:Nfm(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	refseq:NP_032717.2|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR002957(Keratin, type I)|interpro:IPR039008|interpro:IPR027697|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005883"(neurofilament)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015643"(toxic substance binding)|go:"GO:0030424"(axon)|go:"GO:0031133"(regulation of axon diameter)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045105"(intermediate filament polymerization or depolymerization)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099182"(presynaptic intermediate filament cytoskeleton)|mint:P08553|hgnc:"MGI:97314"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:2HBUZIEhbbrfamAhbq7gyuRUaTk10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:P08551	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-445199|uniprotkb:Q8K0Z0|ensembl:ENSMUSP00000022639	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:nfl_mouse(display_long)|uniprotkb:Neurofilament triplet L protein(gene name synonym)|uniprotkb:68 kDa neurofilament protein(gene name synonym)|uniprotkb:Nefl(gene name)|psi-mi:Nefl(display_short)|uniprotkb:Nfl(gene name synonym)|uniprotkb:Nf68(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	refseq:NP_035040.1|ensembl:ENSMUSG00000022055(gene)|ensembl:ENSMUST00000022639(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0005883"(neurofilament)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099182"(presynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1903935"(response to sodium arsenite)|go:"GO:1903937"(response to acrylamide)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027692|interpro:IPR039008|mint:P08551|reactome:R-MMU-438066|reactome:R-MMU-5673001|go:"GO:0098981"(cholinergic synapse)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031133"(regulation of axon diameter)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045105"(intermediate filament polymerization or depolymerization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051258"(protein polymerization)|go:"GO:0051412"(response to corticosterone)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0060074"(synapse maturation)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|dip:DIP-31944N|hgnc:"MGI:97313"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:E8KK2ppZXyLXIlFZp/pjXv7GBEU10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:D3YZ62	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-16736940|ensembl:ENSMUSP00000120444	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:d3yz62_mouse(display_long)|uniprotkb:Myo5a(gene name)|psi-mi:Myo5a(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	ensembl:ENSMUSG00000034593(gene)|ensembl:ENSMUST00000136731(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0016459"(myosin complex)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002710(Dilute)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR027417|interpro:IPR036103|interpro:IPR037988|refseq:XP_006510895.1|hgnc:"MGI:105976"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:ctdjOxzcKiJ6CybKxHRxG+9KRi810090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:Q3U1V8	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-11795662|uniprotkb:Q8BIG8|uniprotkb:E9QLZ4|ensembl:ENSMUSP00000041819	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:m3k9_mouse(display_long)|uniprotkb:Map3k9(gene name)|psi-mi:Map3k9(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	refseq:NP_001167578.1|refseq:NP_796369.2|ensembl:ENSMUSG00000042724(gene)|ensembl:ENSMUST00000035987(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004706"(JUN kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008219"(cell death)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016231(Mitogen-activated protein kinase kinase kinase, 9/10/11)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035779|interpro:IPR036028|hgnc:"MGI:2449952"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:OdB+Xu/C4vCXaWN1Hd4QT2u87xY10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:F6Q750	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-16736917|ensembl:ENSMUSP00000119885	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:f6q750_mouse(display_long)|uniprotkb:Macf1(gene name)|psi-mi:Macf1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	ensembl:ENSMUSG00000028649(gene)|ensembl:ENSMUST00000134458(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008017"(microtubule binding)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR011992(EF-Hand type)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036534|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|hgnc:"MGI:108559"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:0MI+RETUooW9GKzvJ7ZtYmfkaXw10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:A2AHG0	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-16730688|ensembl:ENSMUSP00000037109|ensembl:ENSMUSP00000086990|uniprotkb:A2AHF9|uniprotkb:Q3TSY0|uniprotkb:Q6PE51	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:lzts3_mouse(display_long)|uniprotkb:ProSAP-interacting protein 1(gene name synonym)|uniprotkb:Lzts3(gene name)|psi-mi:Lzts3(display_short)|uniprotkb:Prosapip1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	ensembl:ENSMUSG00000037703(gene)|ensembl:ENSMUST00000045761(transcript)|ensembl:ENSMUST00000089561(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043621"(protein self-association)|go:"GO:0045202"(synapse)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|interpro:IPR033295|refseq:NP_001277956.1|refseq:NP_001277957.1|refseq:NP_922936.3|refseq:XP_017173693.1|hgnc:"MGI:2656976"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:5+8Res6l89KP2ziP7nHoTRP25p010090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:D3Z6V7	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-16736899|ensembl:ENSMUSP00000093995	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:d3z6v7_mouse(display_long)|uniprotkb:Iqsec2(gene name)|psi-mi:Iqsec2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	ensembl:ENSMUSG00000041115(gene)|ensembl:ENSMUST00000096275(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0032012"(regulation of ARF protein signal transduction)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000904(SEC7-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR033742|interpro:IPR035999|refseq:NP_001005475.1|hgnc:"MGI:3528396"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:ro/HyurDjGvwV4Ibtac4sMB9M2w10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:Q8R0S2	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-772277|uniprotkb:Q3TZC3|uniprotkb:Q5DU15|ensembl:ENSMUSP00000098712	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:iqec1_mouse(display_long)|uniprotkb:Iqsec1(gene name)|psi-mi:Iqsec1(display_short)|uniprotkb:Kiaa0763(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	refseq:NP_001127855.1|ensembl:ENSMUSG00000034312(gene)|ensembl:ENSMUST00000101153(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008289"(lipid binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0060996"(dendritic spine development)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000904(SEC7-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR030737|interpro:IPR033742|interpro:IPR035999|hgnc:"MGI:1196356"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:BZg7CaLndE4ak8KXs34YFf9iBRQ10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:P46660	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-400482|uniprotkb:Q61958|uniprotkb:Q8VCW5|ensembl:ENSMUSP00000041347	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:ainx_mouse(display_long)|uniprotkb:Ina(gene name)|psi-mi:Ina(display_short)|uniprotkb:66 kDa neurofilament protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	refseq:NP_666212.3|ensembl:ENSMUSG00000034336(gene)|ensembl:ENSMUST00000037636(transcript)|go:"GO:0005883"(neurofilament)|go:"GO:0007399"(nervous system development)|go:"GO:0030154"(cell differentiation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027703|interpro:IPR039008|mint:P46660|hgnc:"MGI:96568"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:amjP0AajB8s2oXmV96wzyfz6evE10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:Q9Z2Y3	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-396980|uniprotkb:Q8K3E1|uniprotkb:Q8K4M8|uniprotkb:Q9Z0E9|uniprotkb:Q9Z216|ensembl:ENSMUSP00000079026	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:home1_mouse(display_long)|uniprotkb:Homer1(gene name)|psi-mi:Homer1(display_short)|uniprotkb:Vesl1(gene name synonym)|uniprotkb:VASP/Ena-related gene up-regulated during seizure and LTP 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	refseq:NP_036112.1|refseq:NP_671705.2|refseq:NP_687036.1|refseq:NP_001271118.1|refseq:NP_001334527.1|ensembl:ENSMUSG00000007617(gene)|ensembl:ENSMUST00000080127(transcript)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044309"(neuron spine)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048875"(chemical homeostasis within a tissue)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098794"(postsynapse)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099186"(structural constituent of postsynapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:2001256"(regulation of store-operated calcium entry)|go:"GO:2001257"(regulation of cation channel activity)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9Z2Y3|reactome:R-MMU-6794361|hgnc:"MGI:1347345"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:aOI1ZRXwOjFH9a3s6Jf1FNfMdiA10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:G3X9V4	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-16736858|ensembl:ENSMUSP00000062284|ensembl:ENSMUSP00000107536	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:g3x9v4_mouse(display_long)|uniprotkb:Grin2b(gene name)|psi-mi:Grin2b(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	ensembl:ENSMUSG00000030209(gene)|ensembl:ENSMUST00000053880(transcript)|ensembl:ENSMUST00000111905(transcript)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0016594"(glycine binding)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018884|interpro:IPR019594|interpro:IPR028082|refseq:NP_032197.3|refseq:XP_006505636.1|refseq:XP_006505637.1|refseq:XP_006505638.1|refseq:XP_011239522.1|refseq:XP_011239523.1|refseq:XP_017176885.1|hgnc:"MGI:95821"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:TvJgPT3ReGz9NXm6u45Im5aW8Og10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:P35438-2	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-16736851|ensembl:ENSMUSP00000109951	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:p35438-2(display_long)|uniprotkb:Glutamate [NMDA] receptor subunit zeta-1(gene name synonym)|uniprotkb:N-methyl-D-aspartate receptor subunit NR1(gene name synonym)|uniprotkb:Grin1(gene name)|psi-mi:Grin1(display_short)|uniprotkb:Glurz1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	ensembl:ENSMUSG00000026959(gene)|ensembl:ENSMUST00000114312(transcript)|intact:EBI-400084(isoform-parent)|hgnc:"MGI:95819"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:pFypyvoeF0qJN5wqkdemmmjee+c10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:F2Z488	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-16736833|ensembl:ENSMUSP00000116381	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:f2z488_mouse(display_long)|uniprotkb:Gria3(gene name)|psi-mi:Gria3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	ensembl:ENSMUSG00000001986(gene)|ensembl:ENSMUST00000139965(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045211"(postsynaptic membrane)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|hgnc:"MGI:95810"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:WQxB6CfXCiab5hckWjlN/qn/PYc10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:P23819-2	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-16736826	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:p23819-2(display_long)|uniprotkb:AMPA-selective glutamate receptor 2(gene name synonym)|uniprotkb:GluR-B(gene name synonym)|uniprotkb:GluR-K2(gene name synonym)|uniprotkb:Glutamate receptor ionotropic, AMPA 2(gene name synonym)|uniprotkb:Gria2(gene name)|psi-mi:Gria2(display_short)|uniprotkb:Glur2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	intact:EBI-77538(isoform-parent)|hgnc:"MGI:95809"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:bgqtBiN8LNplRvpWV08Vrd7lIQU10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:P23242	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-298630|ensembl:ENSMUSP00000064536|ensembl:ENSMUSP00000151620|uniprotkb:Q544I7|uniprotkb:Q8CE05	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:cxa1_mouse(display_long)|uniprotkb:Gja1(gene name)|psi-mi:Gja1(display_short)|uniprotkb:Cxn-43(gene name synonym)|uniprotkb:Connexin-43(gene name synonym)|uniprotkb:Gap junction 43 kDa heart protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	go:"GO:0005771"(multivesicular body)|go:"GO:0030054"(cell junction)|ensembl:ENSMUSG00000050953(gene)|ensembl:ENSMUST00000068581(transcript)|ensembl:ENSMUST00000220069(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001764"(neuron migration)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0001947"(heart looping)|go:"GO:0002070"(epithelial cell maturation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002931"(response to ischemia)|go:"GO:0003104"(positive regulation of glomerular filtration)|go:"GO:0003158"(endothelium development)|go:"GO:0003294"(atrial ventricular junction remodeling)|go:"GO:0003347"(epicardial cell to mesenchymal cell transition)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005243"(gap junction channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0007507"(heart development)|go:"GO:0007512"(adult heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0009268"(response to pH)|go:"GO:0009749"(response to glucose)|go:"GO:0010232"(vascular transport)|go:"GO:0005882"(intermediate filament)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010643"(cell communication by chemical coupling)|go:"GO:0010644"(cell communication by electrical coupling)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0005886"(plasma membrane)|go:"GO:0010652"(positive regulation of cell communication by chemical coupling)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014704"(intercalated disc)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015631"(tubulin binding)|go:"GO:0015867"(ATP transport)|go:"GO:0005921"(gap junction)|go:"GO:0005922"(connexin complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007154"(cell communication)|go:"GO:0016020"(membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030500"(regulation of bone mineralization)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032277"(negative regulation of gonadotropin secretion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034634"(glutathione transmembrane transporter activity)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042311"(vasodilation)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043292"(contractile fiber)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045121"(membrane raft)|go:"GO:0071253"(connexin binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0071467"(cellular response to pH)|go:"GO:0086075"(gap junction channel activity involved in cardiac conduction electrical coupling)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099111"(microtubule-based transport)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140115"(export across plasma membrane)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|go:"GO:1903763"(gap junction channel activity involved in cell communication by electrical coupling)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905332"(positive regulation of morphogenesis of an epithelium)|go:"GO:1905772"(positive regulation of mesodermal cell differentiation)|go:"GO:0070160"(tight junction)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045844"(positive regulation of striated muscle tissue development)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0046697"(decidualization)|go:"GO:0046849"(bone remodeling)|go:"GO:0046850"(regulation of bone remodeling)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0055077"(gap junction hemi-channel activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060156"(milk ejection reflex)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060312"(regulation of blood vessel remodeling)|go:"GO:0060348"(bone development)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061337"(cardiac conduction)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|go:"GO:2000987"(positive regulation of behavioral fear response)|interpro:IPR000500(Connexins)|interpro:IPR002261("Gap junction alpha-1 protein (Cx43)")|interpro:IPR013092(Connexin, N-terminal)|interpro:IPR013124("Gap junction alpha-1 protein (Cx43), C-terminal")|interpro:IPR017990|interpro:IPR019570|interpro:IPR034634|interpro:IPR035091|interpro:IPR038359|mint:P23242|reactome:R-MMU-190840|reactome:R-MMU-190861|reactome:R-MMU-190873|reactome:R-MMU-191650|reactome:R-MMU-196025|reactome:R-MMU-9013406|go:"GO:1905867"(epididymis development)|refseq:NP_034418.1|dip:DIP-29207N|hgnc:"MGI:95713"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:y7Yg1+W6tlVZnaRALQBCWQppVf010090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:Q5F258	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-16735713|ensembl:ENSMUSP00000098375	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:q5f258_mouse(display_long)|uniprotkb:Git1(gene name)|psi-mi:Git1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	ensembl:ENSMUSG00000011877(gene)|ensembl:ENSMUST00000100812(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR002110(Ankyrin)|interpro:IPR013724("Spa2 homology (SHD) of GIT")|interpro:IPR020683|interpro:IPR022018|interpro:IPR032352|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|refseq:XP_006533012.1|hgnc:"MGI:1927140"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:w9oRo1556FC2b4vWr5xT7wnG+wI10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:Q9WV92-7	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-16736817	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:q9wv92-7(display_long)|uniprotkb:Erythrocyte membrane protein band 4.1-like 3(gene name synonym)|uniprotkb:4.1B(gene name synonym)|uniprotkb:Differentially expressed in adenocarcinoma of the lung protein 1(gene name synonym)|uniprotkb:Epb41l3(gene name)|psi-mi:Epb41l3(display_short)|uniprotkb:Dal1(gene name synonym)|uniprotkb:Epb4.1l3(gene name synonym)|uniprotkb:Kiaa0987(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	intact:EBI-911885(isoform-parent)|hgnc:"MGI:103008"(identity)	go:"GO:0014069"(postsynaptic density)	-	isoform-comment:Inferred from the cDNA sequence of Ref.2. Contains a phosphoserine at position 451. Contains a phosphoserine at position 525.	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:aYfLjXnpojAImWx4DnrDRzsqIws10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:Q3UVU8	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-16736804|ensembl:ENSMUSP00000094890	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:q3uvu8_mouse(display_long)|uniprotkb:Dlgap1(gene name)|psi-mi:Dlgap1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	ensembl:ENSMUSG00000003279(gene)|ensembl:ENSMUST00000097288(transcript)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0045202"(synapse)|interpro:IPR005026(Guanylate-kinase-associated protein)|interpro:IPR030524|refseq:NP_001121653.1|hgnc:"MGI:1346065"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:u4/fQ+K2NGlUOTQxRoYgNqaA3tA10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:Q62108-3	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-16736796|ensembl:ENSMUSP00000156345	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:q62108-3(display_long)|uniprotkb:Dlg4(gene name)|psi-mi:Dlg4(display_short)|uniprotkb:Dlgh4(gene name synonym)|uniprotkb:Psd95(gene name synonym)|uniprotkb:Postsynaptic density protein 95(gene name synonym)|uniprotkb:Synapse-associated protein 90(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	ensembl:ENSMUSG00000020886(gene)|ensembl:ENSMUST00000231415(transcript)|intact:EBI-300895(isoform-parent)|hgnc:"MGI:1277959"(identity)	go:"GO:0014069"(postsynaptic density)	-	isoform-comment:No experimental confirmation available.	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:1gPOZVgEhki6y8UZL1IzJFGbx7E10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:Q91XM9-3	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-16736788	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:q91xm9-3(display_long)|uniprotkb:Channel-associated protein of synapse-110(gene name synonym)|uniprotkb:Postsynaptic density protein PSD-93(gene name synonym)|uniprotkb:PSD93-gamma(isoform synonym)|uniprotkb:Dlg2(gene name)|psi-mi:Dlg2(display_short)|uniprotkb:Dlgh2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	intact:EBI-400138(isoform-parent)|hgnc:"MGI:1344351"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:db97cUUt1omPHpqf+VEvsIdyV9410090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:F6QQP6	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-16735620|ensembl:ENSMUSP00000121506	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:f6qqp6_mouse(display_long)|uniprotkb:Dab2ip(gene name)|psi-mi:Dab2ip(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	ensembl:ENSMUSG00000026883(gene)|ensembl:ENSMUST00000156669(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043087"(regulation of GTPase activity)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR021887|interpro:IPR023152|interpro:IPR030403|interpro:IPR039360|hgnc:"MGI:1916851"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:/7gN6McnRgZHmSFed1ql2s2XeeU10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:O35927	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-774108|uniprotkb:B2RR80	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:ctnd2_mouse(display_long)|uniprotkb:Neural plakophilin-related ARM-repeat protein(gene name synonym)|uniprotkb:Neurojungin(gene name synonym)|uniprotkb:Ctnnd2(gene name)|psi-mi:Ctnnd2(display_short)|uniprotkb:Catnd2(gene name synonym)|uniprotkb:Nprap(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	go:"GO:0001763"(morphogenesis of a branching structure)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007612"(learning)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0045296"(cadherin binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050808"(synapse organization)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR028435|refseq:NP_032755.2|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR000225(Armadillo)|mint:O35927|hgnc:"MGI:1195966"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:/YXEXiU6UKZhK6McB762K0GKcN010090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:Q8BS72	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-16736758|ensembl:ENSMUSP00000124689	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:q8bs72_mouse(display_long)|uniprotkb:Ctnna2(gene name)|psi-mi:Ctnna2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	ensembl:ENSMUSG00000063063(gene)|ensembl:ENSMUST00000162273(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030047|interpro:IPR036723|hgnc:"MGI:88275"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:upyKF1Ypdcy/NSgiUCN9XnFjfu010090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:Q80YA9-2	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-16735613	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:q80ya9-2(display_long)|uniprotkb:Cnksr2(gene name)|psi-mi:Cnksr2(display_short)|uniprotkb:Kiaa0902(gene name synonym)|uniprotkb:CNK homolog protein 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	intact:EBI-771429(isoform-parent)|hgnc:"MGI:2661175"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:npQ8kx+1+lc3qlZWDdj/vczGq6810090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:P49025-3	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-16736749	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:p49025-3(display_long)|uniprotkb:Rho-interacting, serine/threonine-protein kinase 21(gene name synonym)|uniprotkb:Citron(isoform synonym)|uniprotkb:Cit(gene name)|psi-mi:Cit(display_short)|uniprotkb:Crik(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	intact:EBI-397301(isoform-parent)|hgnc:"MGI:105313"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:LsDrbX4GwS3kSPuSp0J1NOwrQfU10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:E9Q4M4	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-16736738|ensembl:ENSMUSP00000109179	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:e9q4m4_mouse(display_long)|uniprotkb:Chchd6(gene name)|psi-mi:Chchd6(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	ensembl:ENSMUSG00000030086(gene)|ensembl:ENSMUST00000113550(transcript)|go:"GO:0061617"(MICOS complex)|interpro:IPR042860|mint:E9Q4M4|refseq:NP_001161208.1|hgnc:"MGI:1913348"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:RWrKkgph3kIeJIrpmDcUssqpFeg10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:H3BKV8	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-16736723|ensembl:ENSMUSP00000135546	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:h3bkv8_mouse(display_long)|uniprotkb:Cdh10(gene name)|psi-mi:Cdh10(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	ensembl:ENSMUSG00000022321(gene)|ensembl:ENSMUST00000176146(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|interpro:IPR002126(Cadherin)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR039808|hgnc:"MGI:107436"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:OcBv45c6bCRpUtgMuh7U754M15810090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:Q80VC9-2	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-16736715	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:q80vc9-2(display_long)|uniprotkb:Marshalin(gene name synonym)|uniprotkb:Protein Nezha(gene name synonym)|uniprotkb:Camsap3(gene name)|psi-mi:Camsap3(display_short)|uniprotkb:Kiaa1543(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	intact:EBI-2125556(isoform-parent)|hgnc:"MGI:1916947"(identity)	go:"GO:0014069"(postsynaptic density)	-	isoform-comment:No experimental confirmation available.	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:VYVB3GXbeUXEpio22OP7SbgnSNI10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:Q923T9-3	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-16736709|ensembl:ENSMUSP00000098398	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:q923t9-3(display_long)|uniprotkb:Camk2g(gene name)|psi-mi:Camk2g(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	intact:EBI-771638(isoform-parent)|ensembl:ENSMUSG00000021820(gene)|ensembl:ENSMUST00000100837(transcript)|hgnc:"MGI:88259"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:XK4XzLpRHb5Pxofk3qXJaodZkMQ10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:Q6PHZ2-2	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-16736701|ensembl:ENSMUSP00000102008	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:q6phz2-2(display_long)|uniprotkb:Camk2d(gene name)|psi-mi:Camk2d(display_short)|uniprotkb:Kiaa4163(gene name synonym)|uniprotkb:Delta 6(isoform synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	intact:EBI-2308458(isoform-parent)|ensembl:ENSMUSG00000053819(gene)|ensembl:ENSMUST00000106400(transcript)|hgnc:"MGI:1341265"(identity)	go:"GO:0014069"(postsynaptic density)	-	isoform-comment:"Ref.1 (BAE25062) sequence is in conflict in position: 478:N->K."	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:K4WFjBG9XZekthJR/1BHwRR4Vh410090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:Q5SVI3	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-2308435|ensembl:ENSMUSP00000099119	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:q5svi3_mouse(display_long)|uniprotkb:Camk2b(gene name)|psi-mi:Camk2b(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	ensembl:ENSMUSG00000057897(gene)|ensembl:ENSMUST00000101585(transcript)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|go:"GO:0106310"(protein serine kinase activity)|hgnc:"MGI:88257"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:fh5zjc/KkXE7JT6y5cenV5kGbyk10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:P11798	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-400384|uniprotkb:Q61284|uniprotkb:Q6ZWN4|ensembl:ENSMUSP00000099952	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:kcc2a_mouse(display_long)|uniprotkb:Camk2a(gene name)|psi-mi:Camk2a(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	refseq:NP_033922.1|refseq:NP_803126.1|refseq:NP_001273738.1|ensembl:ENSMUSG00000024617(gene)|ensembl:ENSMUST00000102888(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060996"(dendritic spine development)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099004"(calmodulin dependent kinase signaling pathway)|go:"GO:0099148"(regulation of synaptic vesicle docking)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099573"(glutamatergic postsynaptic density)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990443"(peptidyl-threonine autophosphorylation)|go:"GO:2000124"(regulation of endocannabinoid signaling pathway)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|mint:P11798|rcsb pdb:1HKX|rcsb pdb:4X3I|rcsb pdb:6TS3|reactome:R-MMU-3371571|reactome:R-MMU-399719|reactome:R-MMU-4086398|reactome:R-MMU-438066|reactome:R-MMU-5576892|reactome:R-MMU-5578775|reactome:R-MMU-5673000|reactome:R-MMU-5673001|reactome:R-MMU-877300|reactome:R-MMU-936837|dip:DIP-31593N|hgnc:"MGI:88256"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:mHdSlhGhe3sMOyO+YGwROtGOGfY10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:Q8C8R3-3	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-16736693|ensembl:ENSMUSP00000043765	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:q8c8r3-3(display_long)|uniprotkb:Ank2(gene name)|psi-mi:Ank2(display_short)|uniprotkb:AnkB(gene name synonym)|uniprotkb:Ankyrin-B(gene name synonym)|uniprotkb:Brain ankyrin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	intact:EBI-774322(isoform-parent)|ensembl:ENSMUST00000044443(transcript)|ensembl:ENSMUSG00000032826(gene)|hgnc:"MGI:88025"(identity)	go:"GO:0014069"(postsynaptic density)	-	isoform-comment:"Ref.1 (BAC27676) sequence is in conflict in position: 1014:V->A. Contains a phosphoserine at position 590."	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:kqQ5dHmD6eoVX6rCUU/5a9tQHH810090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2CG49	uniprotkb:E9Q777	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-16736674|ensembl:ENSMUSP00000116015	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:e9q777_mouse(display_long)|uniprotkb:Akap11(gene name)|psi-mi:Akap11(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737031|imex:IM-26370-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	ensembl:ENSMUSG00000022016(gene)|ensembl:ENSMUST00000123853(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0019207"(kinase regulator activity)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0036010"(protein localization to endosome)|go:"GO:1903142"(positive regulation of establishment of endothelial barrier)|interpro:IPR008382(A-kinase anchor 110 kDa)|refseq:NP_001157975.1|refseq:XP_006518962.2|hgnc:"MGI:2684060"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/03/08	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:smAJSZ7No4B2BfQIgjaZa330BRE10090	rigid:Kt8xGIZLItyEReG+Iw8QJoknK2I	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:A4GZ26	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-8526464|intact:MINT-7232686|ensembl:ENSMUSP00000127249	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:a4gz26_mouse(display_long)|uniprotkb:Iqsec2(gene name)|psi-mi:Iqsec2(display_short)|uniprotkb:IQArfGEF(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_001108136.1|ensembl:ENSMUSG00000041115(gene)|ensembl:ENSMUST00000168786(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0032012"(regulation of ARF protein signal transduction)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000904(SEC7-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR033742|interpro:IPR035999|mint:A4GZ26|hgnc:"MGI:3528396"(identity)	go:"GO:0014069"(postsynaptic density)	-	comment:mint	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:Q5seAZYl6EgyG0cl/AMiAXLZUc810090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q8CGM1	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-8014984|uniprotkb:B1ASB7|intact:MINT-1504097|uniprotkb:Q6PGN0|uniprotkb:B1ASB8|uniprotkb:Q3UNE2|uniprotkb:Q3TYC8|uniprotkb:Q3UN11|uniprotkb:B2FDE3|ensembl:ENSMUSP00000101636	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:agrb2_mouse(display_long)|uniprotkb:Adgrb2(gene name)|psi-mi:Adgrb2(display_short)|uniprotkb:Bai2(gene name synonym)|uniprotkb:Brain-specific angiogenesis inhibitor 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_001186625.1|refseq:NP_775094.2|refseq:NP_001277643.1|refseq:NP_001277644.1|ensembl:ENSMUSG00000028782(gene)|ensembl:ENSMUST00000106015(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0033173"(calcineurin-NFAT signaling cascade)|go:"GO:0051965"(positive regulation of synapse assembly)|interpro:IPR000203(GPS)|interpro:IPR000832(GPCR, family 2, secretin-like)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR001879(GPCR, family 2, extracellular region)|interpro:IPR008077(GPCR, family 2, brain-specific angiogenesis inhibitor)|interpro:IPR017981|interpro:IPR032471|interpro:IPR036383|interpro:IPR036445|interpro:IPR043838|hgnc:"MGI:2451244�"(identity)	go:"GO:0014069"(postsynaptic density)	-	function:Might be involved in angiogenesis inhibition|comment:mint|comment:homomint	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:8rlZowKB2ecMLVMojYSZDIwjx9410090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q811P8	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-6949116|ensembl:ENSMUSP00000133898|intact:MINT-268399|uniprotkb:B9EHJ8|uniprotkb:Q6A010	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:rhg32_mouse(display_long)|uniprotkb:RhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling(gene name synonym)|uniprotkb:Rics(gene name synonym)|uniprotkb:p200RhoGAP(gene name synonym)|uniprotkb:p250GAP(gene name synonym)|uniprotkb:Arhgap32(gene name)|psi-mi:Arhgap32(display_short)|uniprotkb:Brain-specific Rho GTPase-activating protein(gene name synonym)|uniprotkb:GAB-associated Cdc42/Rac GTPase-activating protein(gene name synonym)|uniprotkb:GC-GAP(gene name synonym)|uniprotkb:Grit(gene name synonym)|uniprotkb:Kiaa0712(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 32(gene name synonym)|uniprotkb:Rho/Cdc42/Rac GTPase-activating protein RICS(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000041444(gene)|ensembl:ENSMUST00000174641(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001650"(fibrillar center)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005938"(cell cortex)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0043197"(dendritic spine)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036028|interpro:IPR036871|interpro:IPR042139|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013406|reactome:R-MMU-9013408|reactome:R-MMU-9013409|reactome:R-MMU-9013423|reactome:R-MMU-9035034|refseq:NP_796353.3|refseq:NP_001182561.1|hgnc:"MGI:2450166"(identity)	go:"GO:0014069"(postsynaptic density)	-	comment:mint	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:4ZVZeciVms1xmC18riIhaDt9wMY10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:P84084	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-7569461|uniprotkb:P26437|intact:UNK-5383724|uniprotkb:A2RTC5|ensembl:ENSMUSP00000020717|ensembl:ENSMUSP00000127281	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:arf5_mouse(display_long)|uniprotkb:Arf5(gene name)|psi-mi:Arf5(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_031506.1|ensembl:ENSMUSG00000020440(gene)|ensembl:ENSMUST00000020717(transcript)|ensembl:ENSMUST00000169841(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|reactome:R-MMU-6807878|reactome:R-MMU-6811434|hgnc:"MGI:99434"(identity)	go:"GO:0014069"(postsynaptic density)	-	function:GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus|comment:mint|comment:homomint	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:da8exbGR3MGxZ6CPZqLvqJbyUYI10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:P63101	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-354751|uniprotkb:P35215|uniprotkb:P70197|uniprotkb:P97286|uniprotkb:Q3TSF1|uniprotkb:Q5EBQ1|ensembl:ENSMUSP00000022894|ensembl:ENSMUSP00000105990|ensembl:ENSMUSP00000105991	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:1433z_mouse(display_long)|uniprotkb:Ywhaz(gene name)|psi-mi:Ywhaz(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:SEZ-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_001240734.1|refseq:NP_001240735.1|refseq:NP_035870.1|refseq:XP_011243654.1|ensembl:ENSMUSG00000022285(gene)|ensembl:ENSMUST00000110361(transcript)|ensembl:ENSMUST00000110362(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0002553"(histamine secretion by mast cell)|go:"GO:0003016"(respiratory system process)|ensembl:ENSMUST00000022894(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031252"(cell leading edge)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035148"(tube formation)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P63101|reactome:R-MMU-111447|reactome:R-MMU-3769402|reactome:R-MMU-392517|reactome:R-MMU-430116|reactome:R-MMU-450604|reactome:R-MMU-512988|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-75035|reactome:R-MMU-9013700|reactome:R-MMU-9614399|dip:DIP-31894N|hgnc:"MGI:109484"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:v2N95HO8sYRWEg2gFtWiYajP1Sc10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:P68510	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-444641|uniprotkb:P11576|uniprotkb:P70198|uniprotkb:Q3TGZ9|ensembl:ENSMUSP00000019109	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:1433f_mouse(display_long)|uniprotkb:Ywhah(gene name)|psi-mi:Ywhah(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_035868.1|ensembl:ENSMUSG00000018965(gene)|ensembl:ENSMUST00000019109(transcript)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006713"(glucocorticoid catabolic process)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0014704"(intercalated disc)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P68510|rcsb pdb:5YQG|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-111447|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-75035|hgnc:"MGI:109194"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:Ew2uUYIXrZ8nnP52xMnGB6KOCqc10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:P61982	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-359843|uniprotkb:O70457|uniprotkb:P35214|uniprotkb:Q4FK44|uniprotkb:Q3UFD6|uniprotkb:Q9UDP2|uniprotkb:Q9UN99|ensembl:ENSMUSP00000051223|ensembl:ENSMUSP00000143631	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:1433g_mouse(display_long)|uniprotkb:Ywhag(gene name)|psi-mi:Ywhag(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_061359.2|ensembl:ENSMUSG00000051391(gene)|ensembl:ENSMUST00000055808(transcript)|ensembl:ENSMUST00000198270(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045202"(synapse)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0098793"(presynapse)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P61982|reactome:R-MMU-111447|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-75035|reactome:R-MMU-8854518|reactome:R-MMU-9614399|hgnc:"MGI:108109"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:u1cd71h0RPgTOEMrQVhOelsxWnM10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:P62259	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-356480|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q63631|ensembl:ENSMUSP00000070993	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:1433e_mouse(display_long)|uniprotkb:Ywhae(gene name)|psi-mi:Ywhae(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000020849(gene)|ensembl:ENSMUST00000067664(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001764"(neuron migration)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0006605"(protein targeting)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|refseq:NP_033562.3|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62259|reactome:R-MMU-111447|reactome:R-MMU-2028269|reactome:R-MMU-205025|reactome:R-MMU-2565942|reactome:R-MMU-3371453|reactome:R-MMU-3371511|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-75035|reactome:R-MMU-8854518|reactome:R-MMU-8876198|hgnc:"MGI:894689"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q920I9	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-776403|uniprotkb:Q059Q1|uniprotkb:Q3U440|uniprotkb:Q80TY3|uniprotkb:Q920J0|ensembl:ENSMUSP00000072509	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:wdr7_mouse(display_long)|uniprotkb:TGF-beta resistance-associated protein TRAG(gene name synonym)|uniprotkb:Wdr7(gene name)|psi-mi:Wdr7(display_short)|uniprotkb:Kiaa0541(gene name synonym)|uniprotkb:Trag(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_001014981.1|refseq:XP_006525540.1|ensembl:ENSMUSG00000040560(gene)|ensembl:ENSMUST00000072726(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0008021"(synaptic vesicle)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:Q920I9|hgnc:"MGI:1860197"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:FH0Q4cn/bo3L5bGOYYViTG2l7eE10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:E9Q2H1	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-11033557|ensembl:ENSMUSP00000105965	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:e9q2h1_mouse(display_long)|uniprotkb:Ubr5(gene name)|psi-mi:Ubr5(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000037487(gene)|ensembl:ENSMUST00000110336(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR000569(HECT)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR024725|interpro:IPR035983|interpro:IPR036053|refseq:NP_001106192.1|hgnc:"MGI:1918040"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:i3KGG0cIlq49L0Pwcv17raS4mAI10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q8CHC4	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-775693	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:synj1_mouse(display_long)|uniprotkb:Synj1(gene name)|psi-mi:Synj1(display_short)|uniprotkb:Kiaa0910(gene name synonym)|uniprotkb:Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	interpro:IPR015047(Region of unknown function DUF1866)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002013(Synaptojanin, N-terminal)|interpro:IPR034971|interpro:IPR034972|interpro:IPR035979|interpro:IPR036691|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:Q8CHC4|go:"GO:0003723"(RNA binding)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014015"(positive regulation of gliogenesis)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030118"(clathrin coat)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0034595"(phosphatidylinositol phosphate 5-phosphatase activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043195"(terminal bouton)|go:"GO:0043812"(phosphatidylinositol-4-phosphate phosphatase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0052658"(inositol-1,4,5-trisphosphate 5-phosphatase activity)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1903423"(positive regulation of synaptic vesicle recycling)|go:"GO:1904980"(positive regulation of endosome organization)|go:"GO:1990175"(EH domain binding)|reactome:R-MMU-1660499|reactome:R-MMU-1855183|reactome:R-MMU-1855204|reactome:R-MMU-8856828|hgnc:"MGI:1354961"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:jBMEFlptiz90uS1F1ajBc7zR3vo10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:O55106	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-2479958|uniprotkb:B2RWV9|uniprotkb:Q5BKR9|ensembl:ENSMUSP00000120830	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:strn_mouse(display_long)|uniprotkb:Strn(gene name)|psi-mi:Strn(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000024077(gene)|ensembl:ENSMUST00000145910(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|go:"GO:0014069"(postsynaptic density)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O55106|reactome:R-MMU-1257604|reactome:R-MMU-6811558|reactome:R-MMU-9009391|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_035630.2|hgnc:"MGI:1333757"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:tUJDyyIWZKuEBcyJKUIbk2dR4JE10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q60864	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-494437|uniprotkb:Q3TT16|uniprotkb:Q8BPH3|uniprotkb:Q99L66|ensembl:ENSMUSP00000025918	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:stip1_mouse(display_long)|uniprotkb:Hsc70/Hsp90-organizing protein(gene name synonym)|uniprotkb:Stip1(gene name)|psi-mi:Stip1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_058017.1|ensembl:ENSMUSG00000024966(gene)|ensembl:ENSMUST00000025918(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043209"(myelin sheath)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0101031"(chaperone complex)|go:"GO:0120293"(dynein axonemal particle)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR041243|mint:Q60864|reactome:R-MMU-3371497|reactome:R-MMU-9696273|hgnc:"MGI:109130"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:f6DTvAcA6tKSLqzw11r9X+rC8ao10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q91Z67	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-16730393|ensembl:ENSMUSP00000095195|uniprotkb:B2RY13|uniprotkb:Q3V1V8|uniprotkb:Q61054	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:srgp2_mouse(display_long)|uniprotkb:Formin-binding protein 2(gene name synonym)|uniprotkb:Formin-binding protein 27(gene name synonym)|uniprotkb:Srgap2(gene name)|psi-mi:Srgap2(display_short)|uniprotkb:Fbp27(gene name synonym)|uniprotkb:Fnbp2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000026425(gene)|ensembl:ENSMUST00000097588(transcript)|go:"GO:0003363"(lamellipodium assembly involved in ameboidal cell migration)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0021816"(extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051014"(actin filament severing)|go:"GO:0060996"(dendritic spine development)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000198(RhoGAP)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR030252|interpro:IPR031160|interpro:IPR035648|interpro:IPR036028|mint:Q91Z67|reactome:R-MMU-5663220|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013406|reactome:R-MMU-9013420|reactome:R-MMU-9013423|reactome:R-MMU-9035034|refseq:NP_001074480.2|refseq:XP_006529197.1|hgnc:"MGI:109605"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:MLCAa8wEQvKNPatehgSzcizs2YI10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q68FG2	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-2255511|ensembl:ENSMUSP00000008991	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:q68fg2_mouse(display_long)|uniprotkb:Sptbn2(gene name)|psi-mi:Sptbn2(display_short)|uniprotkb:Spnb3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_067262.1|refseq:XP_006531767.1|refseq:XP_006531768.1|ensembl:ENSMUSG00000067889(gene)|ensembl:ENSMUST00000008991(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007416"(synapse assembly)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008091"(spectrin)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0021692"(cerebellar Purkinje cell layer morphogenesis)|go:"GO:0030534"(adult behavior)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051693"(actin filament capping)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098918"(structural constituent of synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|go:"GO:0099189"(postsynaptic spectrin-associated cytoskeleton)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|interpro:IPR041681|reactome:R-MMU-2132295|reactome:R-MMU-375165|reactome:R-MMU-445095|reactome:R-MMU-5673001|reactome:R-MMU-6807878|hgnc:"MGI:1313261"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:2F7U0dl21KxXpc9Z2sk7D/wzQvM10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q62261	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-397843|ensembl:ENSMUSP00000006629|ensembl:ENSMUSP00000011877|uniprotkb:A2AFU1|uniprotkb:Q3TEM7|uniprotkb:Q5SQL8|uniprotkb:Q5SQL9|uniprotkb:Q9QWJ7	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:sptb2_mouse(display_long)|uniprotkb:Sptbn1(gene name)|psi-mi:Sptbn1(display_short)|uniprotkb:Spnb-2(gene name synonym)|uniprotkb:Spnb2(gene name synonym)|uniprotkb:Sptb2(gene name synonym)|uniprotkb:Beta-II spectrin(gene name synonym)|uniprotkb:Fodrin beta chain(gene name synonym)|uniprotkb:Embryonic liver fodrin(gene name synonym)|uniprotkb:Elf(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000020315(gene)|ensembl:ENSMUST00000006629(transcript)|ensembl:ENSMUST00000011877(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008091"(spectrin)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030673"(axolemma)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031430"(M band)|go:"GO:0032437"(cuticular plate)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0071709"(membrane assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|interpro:IPR041681|mint:Q62261|rcsb pdb:1BTN|rcsb pdb:1MPH|rcsb pdb:6M3P|reactome:R-MMU-375165|reactome:R-MMU-445095|reactome:R-MMU-5673001|reactome:R-MMU-6807878|reactome:R-MMU-9013420|reactome:R-MMU-9013424|refseq:NP_033286.2|refseq:NP_787030.2|refseq:XP_006514662.1|refseq:XP_006514663.1|dip:DIP-31558N|hgnc:"MGI:98388"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:N6xVFU+ocY6PXsIz5ZIsA05bGPs10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:F6V513	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-16737590|ensembl:ENSMUSP00000120487	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:f6v513_mouse(display_long)|uniprotkb:Sorbs2(gene name)|psi-mi:Sorbs2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000031626(gene)|ensembl:ENSMUST00000146627(transcript)|hgnc:"MGI:1924574"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:97HhT1LaHnYTz7GvuX5Atlng3n410090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q62417	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-2365368|uniprotkb:Q80TF8|uniprotkb:Q8BZI3|uniprotkb:Q8K3Y2|uniprotkb:Q921F8|uniprotkb:Q9Z0Z8|uniprotkb:Q9Z0Z9	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:srbs1_mouse(display_long)|uniprotkb:Sorbs1(gene name)|psi-mi:Sorbs1(display_short)|uniprotkb:Kiaa1296(gene name synonym)|uniprotkb:Sh3d5(gene name synonym)|uniprotkb:Ponsin(gene name synonym)|uniprotkb:c-Cbl-associated protein(gene name synonym)|uniprotkb:SH3 domain protein 5(gene name synonym)|uniprotkb:SH3P12(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_001030134.1|refseq:NP_001030135.1|refseq:NP_001030136.1|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR035606|interpro:IPR035610|interpro:IPR035611|interpro:IPR036028|mint:Q62417|go:"GO:0001725"(stress fiber)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005899"(insulin receptor complex)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016600"(flotillin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904393"(regulation of skeletal muscle acetylcholine-gated channel clustering)|reactome:R-MMU-445355|hgnc:"MGI:700014"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:3+0ZfSkNB+9ujOF3uyXmP2ovl8A10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:P56564	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-2310175|uniprotkb:Q99P53|ensembl:ENSMUSP00000005493	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:eaa1_mouse(display_long)|uniprotkb:Slc1a3(gene name)|psi-mi:Slc1a3(display_short)|uniprotkb:Eaat1(gene name synonym)|uniprotkb:Gmt1(gene name synonym)|uniprotkb:Sodium-dependent glutamate/aspartate transporter 1(gene name synonym)|uniprotkb:High-affinity neuronal glutamate transporter(gene name synonym)|uniprotkb:Glial high affinity glutamate transporter(gene name synonym)|uniprotkb:Solute carrier family 1 member 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_683740.1|go:"GO:1902476"(chloride transmembrane transport)|interpro:IPR001991("Sodium:dicarboxylate symporter")|interpro:IPR018107|interpro:IPR036458|mint:P56564|reactome:R-MMU-210455|reactome:R-MMU-210500|reactome:R-MMU-425393|ensembl:ENSMUSG00000005360(gene)|ensembl:ENSMUST00000005493(transcript)|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005314"(high-affinity glutamate transmembrane transporter activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009449"(gamma-aminobutyric acid biosynthetic process)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0015172"(acidic amino acid transmembrane transporter activity)|go:"GO:0015501"("glutamate:sodium symporter activity")|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0016597"(amino acid binding)|go:"GO:0021545"(cranial nerve development)|go:"GO:0031223"(auditory behavior)|go:"GO:0042493"|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043200"(response to amino acid)|go:"GO:0043490"(malate-aspartate shuttle)|go:"GO:0045202"(synapse)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051938"(L-glutamate import)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071944"(cell periphery)|go:"GO:0098712"(L-glutamate import across plasma membrane)|go:"GO:0098796"(membrane protein complex)|go:"GO:0140009"(L-aspartate import across plasma membrane)|hgnc:"MGI:99917"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:XRqZRejwe6BDoF8prYq/KDlMn2010090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:F6VQZ6	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-16737580|ensembl:ENSMUSP00000120862	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:f6vqz6_mouse(display_long)|uniprotkb:Shisa6(gene name)|psi-mi:Shisa6(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUST00000123454(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR026910|ensembl:ENSMUSG00000053930(gene)|hgnc:"MGI:2685725"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:oaAjEzkIxh9KG4Gd3lqd9PLM7dk10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q4ACU6	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-771450|uniprotkb:Q69ZD8|intact:EBI-8401154|intact:MINT-4130064|uniprotkb:F8S0X0|uniprotkb:F8S0X2|uniprotkb:F8S0X3|uniprotkb:F8S0X5|uniprotkb:F8S0X6|uniprotkb:Q9JJZ3|uniprotkb:S6BMD3|uniprotkb:S6CCV8|ensembl:ENSMUSP00000104932	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:shan3_mouse(display_long)|uniprotkb:Proline-rich synapse-associated protein 2(gene name synonym)|uniprotkb:SPANK-2(gene name synonym)|uniprotkb:Shank3(gene name)|psi-mi:Shank3(display_short)|uniprotkb:Kiaa1650(gene name synonym)|uniprotkb:Prosap2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_067398.2|dip:DIP-32262N|ensembl:ENSMUSG00000022623(gene)|ensembl:ENSMUST00000109309(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001838"(embryonic epithelial tube formation)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007416"(synapse assembly)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0021773"(striatal medium spiny neuron differentiation)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030534"(adult behavior)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0051835"(positive regulation of synapse structural plasticity)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097107"(postsynaptic density assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097114"(NMDA glutamate receptor clustering)|go:"GO:0097117"(guanylate kinase-associated protein clustering)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035640"(exploration behavior)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0040011"(locomotion)|go:"GO:0042297"(vocal learning)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043621"(protein self-association)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045794"(negative regulation of cell volume)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048170"(positive regulation of long-term neuronal synaptic plasticity)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1900451"(positive regulation of glutamate receptor signaling pathway)|go:"GO:1900452"(regulation of long-term synaptic depression)|go:"GO:1904717"(regulation of AMPA glutamate receptor clustering)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|go:"GO:2000822"(regulation of behavioral fear response)|go:"GO:2000969"(positive regulation of AMPA receptor activity)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|mint:Q4ACU6|rcsb pdb:3O5N|rcsb pdb:5IZU|rcsb pdb:6KYH|rcsb pdb:6KYK|reactome:R-MMU-6794361|reactome:R-MMU-8853659|hgnc:"MGI:1930016"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:40CZZZ4qetQSv6a6gsUMVeL0c+o10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q80Z38-3	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-16737571|ensembl:ENSMUSP00000146440	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:q80z38-3(display_long)|uniprotkb:Cortactin-binding protein 1(gene name synonym)|uniprotkb:Shank2(gene name)|psi-mi:Shank2(display_short)|uniprotkb:Cortbp1(gene name synonym)|uniprotkb:Kiaa1022(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	intact:EBI-770338(isoform-parent)|ensembl:ENSMUSG00000037541(gene)|ensembl:ENSMUST00000146006(transcript)|hgnc:"MGI:2671987"(identity)	go:"GO:0014069"(postsynaptic density)	-	isoform-comment:Contains a phosphoserine at position 162.	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:nSuK3V81EK4IT07tk6V8ZgrwB2U10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:D3YZU5	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-16737529|ensembl:ENSMUSP00000103567	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:d3yzu5_mouse(display_long)|uniprotkb:Shank1(gene name)|psi-mi:Shank1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000038738(gene)|ensembl:ENSMUST00000107934(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0014069"(postsynaptic density)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|refseq:XP_006540929.1|hgnc:"MGI:3613677"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:krLJHujObgducGteePyU78Ab/SI10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:D3YUS5	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-16737508|ensembl:ENSMUSP00000114964	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:d3yus5_mouse(display_long)|uniprotkb:Rasal2(gene name)|psi-mi:Rasal2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000070565(gene)|ensembl:ENSMUST00000132699(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|go:"GO:0043087"(regulation of GTPase activity)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR039360|hgnc:"MGI:2443881"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:SNcczm7d8jhVYbXxDu3ZpybR0fE10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q9Z268	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-2013210|uniprotkb:Q99K69|ensembl:ENSMUSP00000031606|ensembl:ENSMUSP00000123266	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:rasl1_mouse(display_long)|uniprotkb:Rasal1(gene name)|psi-mi:Rasal1(display_short)|uniprotkb:Rasal(gene name synonym)|uniprotkb:RAS protein activator like 1(gene name synonym)|uniprotkb:Ras GTPase-activating-like protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:XP_006530272.1|refseq:XP_006530273.1|refseq:NP_038860.2|ensembl:ENSMUSG00000029602(gene)|ensembl:ENSMUST00000031606(transcript)|ensembl:ENSMUST00000156722(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1903861"(positive regulation of dendrite extension)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001562(Tec/Btk)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023152|interpro:IPR028555|interpro:IPR035892|interpro:IPR037776|interpro:IPR039360|mint:Q9Z268|reactome:R-MMU-5658442|hgnc:"MGI:1330842"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:VbTtsNfJC0uXiZYAtnOIFBPfLkA10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:P62823	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-4286215|uniprotkb:Q62858|uniprotkb:Q62974|uniprotkb:Q63482|uniprotkb:Q9CXQ1|ensembl:ENSMUSP00000132945	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:rab3c_mouse(display_long)|uniprotkb:Rab3c(gene name)|psi-mi:Rab3c(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_076341.1|ensembl:ENSMUSG00000021700(gene)|ensembl:ENSMUST00000167824(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037872|reactome:R-MMU-8873719|hgnc:"MGI:1914545"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:F0BXS2E7Unlk+uNhGFX8SXRN9hA10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:P63011	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-398393|uniprotkb:P05713|uniprotkb:Q3TSL4|ensembl:ENSMUSP00000034301|ensembl:ENSMUSP00000105719|ensembl:ENSMUSP00000105720|ensembl:ENSMUSP00000105717	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:rab3a_mouse(display_long)|uniprotkb:Rab3a(gene name)|psi-mi:Rab3a(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_001159871.1|refseq:NP_033027.1|ensembl:ENSMUSG00000031840(gene)|refseq:XP_006509666.1|refseq:NP_001314976.1|dip:DIP-31051N|ensembl:ENSMUST00000034301(transcript)|ensembl:ENSMUST00000110090(transcript)|ensembl:ENSMUST00000110092(transcript)|ensembl:ENSMUST00000110093(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0003016"(respiratory system process)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009306"(protein secretion)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030141"(secretory granule)|go:"GO:0030324"(lung development)|go:"GO:0030424"(axon)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0031630"(regulation of synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036465"(synaptic vesicle recycling)|go:"GO:0043195"(terminal bouton)|go:"GO:0043229"(intracellular organelle)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0050975"(sensory perception of touch)|go:"GO:0051021"(GDP-dissociation inhibitor binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0060203"(clathrin-sculpted glutamate transport vesicle membrane)|go:"GO:0060478"(acrosomal vesicle exocytosis)|go:"GO:0061670"(evoked neurotransmitter secretion)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|go:"GO:1905684"(regulation of plasma membrane repair)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037872|mint:P63011|reactome:R-MMU-181429|reactome:R-MMU-181430|reactome:R-MMU-210500|reactome:R-MMU-212676|reactome:R-MMU-264642|reactome:R-MMU-6798695|reactome:R-MMU-8873719|reactome:R-MMU-8876198|reactome:R-MMU-888590|hgnc:"MGI:97843"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:Skrsn0x0LP/jAuOk1LQ4ataeiDA10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:P53994	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-444664|uniprotkb:Q3UK45|ensembl:ENSMUSP00000057664	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:rab2a_mouse(display_long)|uniprotkb:Rab2(gene name synonym)|uniprotkb:Rab2a(gene name)|psi-mi:Rab2a(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_067493.1|ensembl:ENSMUSG00000047187(gene)|ensembl:ENSMUST00000060232(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P53994|reactome:R-MMU-162658|reactome:R-MMU-8873719|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|hgnc:"MGI:1928750"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:gBkMWVEMfkyF8vxEHTY8IM6VYAI10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:P61027	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-911581|uniprotkb:O88386|uniprotkb:Q9D7X6|ensembl:ENSMUSP00000021001	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:rab10_mouse(display_long)|uniprotkb:Rab10(gene name)|psi-mi:Rab10(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_057885.1|dip:DIP-37720N|ensembl:ENSMUSG00000020671(gene)|ensembl:ENSMUST00000021001(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0031489"(myosin V binding)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045200"(establishment of neuroblast polarity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051021"(GDP-dissociation inhibitor binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0097051"(establishment of protein localization to endoplasmic reticulum membrane)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P61027|reactome:R-MMU-6798695|reactome:R-MMU-8873719|reactome:R-MMU-8876198|hgnc:"MGI:105066"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:ZbfLtWtXl3z6/MYyhiZp6P1Y5tE10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:P42669	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-773823|ensembl:ENSMUSP00000059404	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:pura_mouse(display_long)|uniprotkb:Purine-rich single-stranded DNA-binding protein alpha(gene name synonym)|uniprotkb:Pura(gene name)|psi-mi:Pura(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_033015.1|refseq:XP_006525787.1|refseq:XP_011245162.1|ensembl:ENSMUSG00000043991(gene)|ensembl:ENSMUST00000051301(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0032422"(purine-rich negative regulatory element binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0098794"(postsynapse)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|interpro:IPR030500|mint:P42669|hgnc:"MGI:103079"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:3LVZ5qdZYeJyeUVPhy3cozxROWs10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:F7CCX1	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-16737458|ensembl:ENSMUSP00000122683	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:f7ccx1_mouse(display_long)|uniprotkb:Ptk2b(gene name)|psi-mi:Ptk2b(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000059456(gene)|ensembl:ENSMUST00000154865(transcript)|go:"GO:0002688"(regulation of leukocyte chemotaxis)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007172"(signal complex assembly)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030500"(regulation of bone mineralization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR005189(Focal adhesion targeting region)|interpro:IPR011009(Protein kinase-like)|interpro:IPR020635|interpro:IPR030610|interpro:IPR036137|hgnc:"MGI:104908"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:ow+ylYfQcHKLDvjXLxYf0PndcZ010090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:P63318	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-397096|uniprotkb:P05697|ensembl:ENSMUSP00000097874	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:kpcg_mouse(display_long)|uniprotkb:Pkcc(gene name synonym)|uniprotkb:Pkcg(gene name synonym)|uniprotkb:Prkcc(gene name synonym)|uniprotkb:Prkcg(gene name)|psi-mi:Prkcg(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_035232.1|ensembl:ENSMUSG00000078816(gene)|ensembl:ENSMUST00000100301(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0032095"(regulation of response to food)|go:"GO:0032425"(positive regulation of mismatch repair)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0043278"(response to morphine)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0044305"(calyx of Held)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048265"(response to pain)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060384"(innervation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0099171"(presynaptic modulation of chemical synaptic transmission)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:0005829"(cytosol)|go:"GO:1990911"(response to psychosocial stress)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014375(Protein kinase C, alpha/beta/gamma types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030425"(dendrite)|go:"GO:0031397"(negative regulation of protein ubiquitination)|interpro:IPR020454|interpro:IPR035892|mint:P63318|reactome:R-MMU-111933|reactome:R-MMU-114516|reactome:R-MMU-416993|reactome:R-MMU-5099900|reactome:R-MMU-76005|hgnc:"MGI:97597"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:t4ukCPPAnYUtHCH1hnQE+uiyfEM10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:P16054	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N|hgnc:"MGI:97599"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q8K1M3	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-2931743|ensembl:ENSMUSP00000035220	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:q8k1m3_mouse(display_long)|uniprotkb:Prkar2a(gene name)|psi-mi:Prkar2a(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0016301"(kinase activity)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005813"(centrosome)|go:"GO:0005930"(axoneme)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0044853"(plasma membrane raft)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|mint:Q8K1M3|ensembl:ENSMUSG00000032601(gene)|ensembl:ENSMUST00000035220(transcript)|refseq:NP_032950.1|hgnc:"MGI:108025"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:x3JyL96ukOXZMw6spgA4CdElv6M10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q9JIG8	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-16733287|ensembl:ENSMUSP00000033489	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:praf2_mouse(display_long)|uniprotkb:Praf2(gene name)|psi-mi:Praf2(display_short)|uniprotkb:DXImx39e(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000031149(gene)|ensembl:ENSMUST00000033489(transcript)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004895(Prenylated rab acceptor PRA1)|refseq:NP_613068.1|hgnc:"MGI:1859607"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:QoVpcIsrF3nsZnIdbqA+kNvViQU10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q3USB7	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-16733252|ensembl:ENSMUSP00000037854|uniprotkb:D3Z0W5|uniprotkb:Q3TSM9	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:plcl1_mouse(display_long)|uniprotkb:Phospholipase C-related but catalytically inactive protein(gene name synonym)|uniprotkb:Plcl1(gene name)|psi-mi:Plcl1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000038349(gene)|ensembl:ENSMUST00000042986(transcript)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0032228"(regulation of synaptic transmission, GABAergic)|go:"GO:0033135"(regulation of peptidyl-serine phosphorylation)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1900122"(positive regulation of receptor binding)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000909(Phospholipase C, phosphatidylinositol-specific , X region)|interpro:IPR001192("Phospholipase C, phosphoinositol-specific, C-terminal (PLC)")|interpro:IPR001711(Phospholipase C, phosphatidylinositol-specific, Y domain)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015359(Phospholipase C, phosphoinositol-specific, EF-hand-like)|interpro:IPR017946|interpro:IPR035892|interpro:IPR042124|mint:Q3USB7|refseq:NP_001108135.1|hgnc:"MGI:3036262"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:UH43D5ZRmFajncAe1RTEkeZ68Pk10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q6ZPQ6-2	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-16737449|ensembl:ENSMUSP00000083292|ensembl:ENSMUSP00000124740	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:q6zpq6-2(display_long)|uniprotkb:Phosphatidylinositol transfer protein, membrane-associated 2(gene name synonym)|uniprotkb:Pyk2 N-terminal domain-interacting receptor 3(gene name synonym)|uniprotkb:Drosophila retinal degeneration B homolog 2(gene name synonym)|uniprotkb:Pitpnm2(gene name)|psi-mi:Pitpnm2(display_short)|uniprotkb:Kiaa1457(gene name synonym)|uniprotkb:Nir3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000029406(gene)|ensembl:ENSMUST00000086123(transcript)|ensembl:ENSMUST00000162812(transcript)|intact:EBI-16744915(isoform-parent)|hgnc:"MGI:1336192"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:/Rb6E3SlDclAVBHFb6FRT6Wd1bw10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:E9Q3L2	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-773641|uniprotkb:Q3UVT5|uniprotkb:Q6DIC7|uniprotkb:Q7TNG2|uniprotkb:Q80Y45	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:pi4ka_mouse(display_long)|uniprotkb:Pik4(gene name synonym)|uniprotkb:Pik4ca(gene name synonym)|uniprotkb:Pi4ka(gene name)|psi-mi:Pi4ka(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_001001983.2|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011009(Protein kinase-like)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR018936|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR042236|refseq:XP_006522097.1|interpro:IPR036940|go:"GO:0004430"(1-phosphatidylinositol 4-kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0044803"(multi-organism membrane organization)|go:"GO:0046786"(viral replication complex formation and maintenance)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0052742"(phosphatidylinositol kinase activity)|reactome:R-MMU-1483248|reactome:R-MMU-1660514|mint:E9Q3L2|hgnc:"MGI:2448506"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:IndUgD7njY39mo58MVLNKGSeD4c10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:P58281	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-776163|uniprotkb:Q3ULA5|uniprotkb:Q8BKU7|uniprotkb:Q8BLL3|uniprotkb:Q8BM08|uniprotkb:Q8R3J7|uniprotkb:A6H6Q3|ensembl:ENSMUSP00000124223	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:opa1_mouse(display_long)|uniprotkb:Optic atrophy protein 1 homolog(gene name synonym)|uniprotkb:Large GTP-binding protein(gene name synonym)|uniprotkb:Opa1(gene name)|psi-mi:Opa1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_598513.1|refseq:XP_006522720.1|ensembl:ENSMUSG00000038084(gene)|ensembl:ENSMUST00000160597(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001843"(neural tube closure)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0007601"(visual perception)|go:"GO:0008017"(microtubule binding)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0010636"(positive regulation of mitochondrial fusion)|go:"GO:0014042"(positive regulation of neuron maturation)|go:"GO:0014850"(response to muscle activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030425"(dendrite)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090102"(cochlea development)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0090398"(cellular senescence)|go:"GO:0097749"(membrane tubulation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904643"(response to curcumin)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR033047|mint:P58281|reactome:R-MMU-169911|hgnc:"MGI:1921393"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:cj1HZs8CYUuCBy4KhYmtO/lvmUk10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q6VNS1-3	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-16737441|ensembl:ENSMUSP00000038324	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:q6vns1-3(display_long)|uniprotkb:GP145-TrkC(gene name synonym)|uniprotkb:Neurotrophic tyrosine kinase receptor type 3(gene name synonym)|uniprotkb:TrkC tyrosine kinase(gene name synonym)|uniprotkb:TrkC NC2(isoform synonym)|uniprotkb:Ntrk3(gene name)|psi-mi:Ntrk3(display_short)|uniprotkb:TrkC(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000059146(gene)|ensembl:ENSMUST00000039438(transcript)|intact:EBI-16744951(isoform-parent)|hgnc:"MGI:97385"(identity)	go:"GO:0014069"(postsynaptic density)	-	isoform-comment:Non-catalytic.	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:ddLMQjFEhb2xvmD9dg8cAmzYgA810090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:P55066	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-774845|uniprotkb:Q6P1E3|uniprotkb:Q8C4F8	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:ncan_mouse(display_long)|uniprotkb:Chondroitin sulfate proteoglycan 3(gene name synonym)|uniprotkb:Ncan(gene name)|psi-mi:Ncan(display_short)|uniprotkb:Cspg3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_031815.2|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR018378|interpro:IPR016187(C-type lectin fold)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR018097|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR000538(Link)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR035976|interpro:IPR036179|mint:P55066|go:"GO:0001501"(skeletal system development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007417"(central nervous system development)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0045202"(synapse)|go:"GO:0051823"(regulation of synapse structural plasticity)|go:"GO:0072534"(perineuronal net)|reactome:R-MMU-1971475|reactome:R-MMU-2022870|reactome:R-MMU-2022923|reactome:R-MMU-2024101|reactome:R-MMU-3000178|hgnc:"MGI:104694"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:FbEuo7LHWAZLqfPi0o0JVHNX4Y410090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:P13595	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-774943|uniprotkb:Q61949|uniprotkb:Q61950|intact:EBI-1018667|uniprotkb:P13594|uniprotkb:Q6LBU8|uniprotkb:Q8BQ96|uniprotkb:Q8C4B2|uniprotkb:Q921P2|uniprotkb:Q9R2A7	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:ncam1_mouse(display_long)|uniprotkb:Ncam1(gene name)|psi-mi:Ncam1(display_short)|uniprotkb:Ncam(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_001074914.1|refseq:NP_001106675.1|refseq:NP_035005.2|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR009138(Neural cell adhesion)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013106(Immunoglobulin V-set)|refseq:NP_001297994.1|interpro:IPR033019|interpro:IPR036116|interpro:IPR036179|mint:P13595|go:"GO:0001928"(regulation of exocyst assembly)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010288"(response to lead ion)|go:"GO:0019902"(phosphatase binding)|go:"GO:0021794"(thalamus development)|go:"GO:0030275"(LRR domain binding)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0031175"(neuron projection development)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0034109"(homotypic cell-cell adhesion)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0048666"(neuron development)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:2001260"(regulation of semaphorin-plexin signaling pathway)|rcsb pdb:2NCM|rcsb pdb:3NCM|reactome:R-MMU-375165|reactome:R-MMU-419037|reactome:R-MMU-445144|reactome:R-MMU-5673001|hgnc:"MGI:97281"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:bEVNNXNFliR5XooeBmVJ5PgeNwc10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q9EPN1	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-527731|uniprotkb:Q8C931|uniprotkb:Q9EPM9|uniprotkb:Q9EPN0|uniprotkb:Q9WVM9|ensembl:ENSMUSP00000029374	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:nbea_mouse(display_long)|uniprotkb:Lysosomal-trafficking regulator 2(gene name synonym)|uniprotkb:Nbea(gene name)|psi-mi:Nbea(display_short)|uniprotkb:Lyst2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_085098.1|ensembl:ENSMUSG00000027799(gene)|ensembl:ENSMUST00000029374(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0008104"(protein localization)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|interpro:IPR000409(Beige/BEACH)|interpro:IPR001680(WD40 repeat)|interpro:IPR010508(Protein of unknown function DUF1088)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR023362|interpro:IPR031570|interpro:IPR036322|interpro:IPR036372|mint:Q9EPN1|refseq:XP_006501586.1|hgnc:"MGI:1347075"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:NWSzMiK/aQ6zHqkCxAoWJSqnrvA10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q9JLN9	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-1571628|uniprotkb:Q811J5|uniprotkb:Q9CST1|ensembl:ENSMUSP00000099510|uniprotkb:Q2KHT0	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:mtor_mouse(display_long)|uniprotkb:FK506-binding protein 12-rapamycin complex-associated protein 1(gene name synonym)|uniprotkb:Rapamycin target protein 1(gene name synonym)|uniprotkb:Mtor(gene name)|psi-mi:Mtor(display_short)|uniprotkb:Mammalian target of rapamycin(gene name synonym)|uniprotkb:Frap1(gene name synonym)|uniprotkb:Frap(gene name synonym)|uniprotkb:FKBP12-rapamycin complex-associated protein(gene name synonym)|uniprotkb:Mechanistic target of rapamycin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000028991(gene)|ensembl:ENSMUST00000103221(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001002"(RNA polymerase III type 1 promoter sequence-specific DNA binding)|go:"GO:0001003"(RNA polymerase III type 2 promoter sequence-specific DNA binding)|go:"GO:0001006"(RNA polymerase III type 3 promoter sequence-specific DNA binding)|go:"GO:0001156"(TFIIIC-class transcription factor complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002296"(T-helper 1 cell lineage commitment)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003179"(heart valve morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0006109"(regulation of carbohydrate metabolic process)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007040"(lysosome organization)|go:"GO:0007281"(germ cell development)|go:"GO:0007420"(brain development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012505"(endomembrane system)|go:"GO:0014042"(positive regulation of neuron maturation)|go:"GO:0014736"(negative regulation of muscle atrophy)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0007569"(cell aging)|go:"GO:0016301"(kinase activity)|go:"GO:0007584"(response to nutrient)|go:"GO:0016310"(phosphorylation)|go:"GO:0016605"(PML body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0007616"(long-term memory)|go:"GO:0030030"(cell projection organization)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0008361"(regulation of cell size)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031529"(ruffle organization)|go:"GO:0031641"(regulation of myelination)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0008542"(visual learning)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0031998"(regulation of fatty acid beta-oxidation)|go:"GO:0032095"(regulation of response to food)|go:"GO:0032868"(response to insulin)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035176"(social behavior)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0042060"(wound healing)|go:"GO:0042220"(response to cocaine)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043200"(response to amino acid)|go:"GO:0043278"(response to morphine)|go:"GO:0043610"(regulation of carbohydrate utilization)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048511"(rhythmic process)|go:"GO:0031929"(TOR signaling)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055006"(cardiac cell development)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071233"(cellular response to leucine)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090335"(regulation of brown fat cell differentiation)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099547"(regulation of translation at synapse, modulating synaptic transmission)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1903691"(positive regulation of wound healing, spreading of epidermal cells)|go:"GO:1904000"(positive regulation of eating behavior)|go:"GO:1904193"(negative regulation of cholangiocyte apoptotic process)|go:"GO:1904197"(positive regulation of granulosa cell proliferation)|go:"GO:1904206"(positive regulation of skeletal muscle hypertrophy)|go:"GO:1904213"(negative regulation of iodide transmembrane transport)|go:"GO:1904056"(positive regulation of cholangiocyte proliferation)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:1904058"(positive regulation of sensory perception of pain)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|go:"GO:1904059"(regulation of locomotor rhythm)|interpro:IPR036738|interpro:IPR036940|mint:Q9JLN9|reactome:R-MMU-1257604|reactome:R-MMU-1632852|reactome:R-MMU-165159|reactome:R-MMU-166208|reactome:R-MMU-3371571|reactome:R-MMU-380972|reactome:R-MMU-389357|reactome:R-MMU-5218920|reactome:R-MMU-5628897|reactome:R-MMU-6804757|reactome:R-MMU-8943724|reactome:R-MMU-9639288|refseq:NP_064393.2|dip:DIP-40570N|hgnc:"MGI:1928394"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:Vc4KAHPBcOKi9OKdCv0vbzLaj2Y10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:D3Z3G6	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-16737397|ensembl:ENSMUSP00000101969	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:d3z3g6_mouse(display_long)|uniprotkb:Mapk3(gene name)|psi-mi:Mapk3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000063065(gene)|ensembl:ENSMUST00000050201(transcript)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005901"(caveola)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|hgnc:"MGI:1346859"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:FmQSfRdAHIJeZIzzrRiDsLLIo1I10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:P63085	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-397697|uniprotkb:P27703|uniprotkb:Q3V1U6|ensembl:ENSMUSP00000156154|ensembl:ENSMUSP00000065983|ensembl:ENSMUSP00000111396	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:mk01_mouse(display_long)|uniprotkb:Mapk1(gene name)|psi-mi:Mapk1(display_short)|uniprotkb:Erk2(gene name synonym)|uniprotkb:Mapk(gene name synonym)|uniprotkb:Prkm1(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 2(gene name synonym)|uniprotkb:MAP kinase isoform p42(gene name synonym)|uniprotkb:ERT1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_001033752.1|refseq:NP_036079.1|refseq:XP_006522210.1|dip:DIP-661N|ensembl:ENSMUST00000069107(transcript)|ensembl:ENSMUST00000115731(transcript)|ensembl:ENSMUST00000232611(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015966"(diadenosine tetraphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019858"(cytosine metabolic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030424"(axon)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035094"(response to nicotine)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043627"(response to estrogen)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046697"(decidualization)|go:"GO:0048538"(thymus development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P63085|reactome:R-MMU-111995|reactome:R-MMU-112409|reactome:R-MMU-112411|reactome:R-MMU-1295596|reactome:R-MMU-162658|reactome:R-MMU-170968|reactome:R-MMU-198753|reactome:R-MMU-202670|reactome:R-MMU-2029482|reactome:R-MMU-2559580|reactome:R-MMU-2559582|reactome:R-MMU-2559585|reactome:R-MMU-2871796|reactome:R-MMU-3371453|reactome:R-MMU-375165|reactome:R-MMU-437239|reactome:R-MMU-445144|reactome:R-MMU-450341|reactome:R-MMU-456926|reactome:R-MMU-5654726|reactome:R-MMU-5654727|reactome:R-MMU-5654732|reactome:R-MMU-5654733|reactome:R-MMU-5663213|reactome:R-MMU-5668599|reactome:R-MMU-5673001|reactome:R-MMU-5674135|reactome:R-MMU-5674499|reactome:R-MMU-5675221|reactome:R-MMU-6798695|reactome:R-MMU-6811558|reactome:R-MMU-74749|reactome:R-MMU-881907|reactome:R-MMU-8939211|reactome:R-MMU-9627069|reactome:R-MMU-9634635|ensembl:ENSMUSG00000063358(gene)|reactome:R-MMU-9634638|reactome:R-MMU-982772|hgnc:"MGI:1346858"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:4STZhl2O+Ilh0lj8wQp8y2vVehA10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:P31938	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-298860|ensembl:ENSMUSP00000005066	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:mp2k1_mouse(display_long)|uniprotkb:Map2k1(gene name)|psi-mi:Map2k1(display_short)|uniprotkb:Mek1(gene name synonym)|uniprotkb:Prkmk1(gene name synonym)|uniprotkb:ERK activator kinase 1(gene name synonym)|uniprotkb:MAPK/ERK kinase 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000004936(gene)|ensembl:ENSMUST00000005066(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003056"(regulation of vascular associated smooth muscle contraction)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021697"(cerebellar cortex formation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043204"(perikaryon)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032402"(melanosome transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034111"(negative regulation of homotypic cell-cell adhesion)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048313"(Golgi inheritance)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048538"(thymus development)|go:"GO:0048678"(response to axon injury)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0060502"(epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0060711"(labyrinthine layer development)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0090398"(cellular senescence)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-MMU-110056|reactome:R-MMU-170968|reactome:R-MMU-445144|reactome:R-MMU-5673000|reactome:R-MMU-5674135|reactome:R-MMU-5674499|refseq:NP_032953.1|dip:DIP-467N|hgnc:"MGI:1346866"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:OOj1juW9l4rnEH/W3CjXWZFKMvw10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q80TE7	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-774900	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:lrrc7_mouse(display_long)|uniprotkb:Protein LAP1(gene name synonym)|uniprotkb:Densin-180(gene name synonym)|uniprotkb:Lrrc7(gene name)|psi-mi:Lrrc7(display_short)|uniprotkb:Kiaa1365(gene name synonym)|uniprotkb:Lap1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_001278381.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR032675|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR036034|reactome:R-MMU-438066|reactome:R-MMU-5673001|reactome:R-MMU-6798695|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0030175"(filopodium)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043194"(axon initial segment)|go:"GO:0043197"(dendritic spine)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|hgnc:"MGI:2676665"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:QWCdfe/eQM/ZaaAG2GwZi+Rf87Q10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q9JM63	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-2309655|ensembl:ENSMUSP00000054356	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:kcj10_mouse(display_long)|uniprotkb:Kcnj10(gene name)|psi-mi:Kcnj10(display_short)|uniprotkb:Potassium channel, inwardly rectifying subfamily J member 10(gene name synonym)|uniprotkb:"Inward rectifier K(+) channel Kir4.1"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_001034573.1|refseq:XP_006496740.2|ensembl:ENSMUSG00000044708(gene)|ensembl:ENSMUST00000056136(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006813"(potassium ion transport)|go:"GO:0007601"(visual perception)|go:"GO:0007628"(adult walking behavior)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0051935"(glutamate reuptake)|go:"GO:0051938"(L-glutamate import)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0060075"(regulation of resting membrane potential)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0097449"(astrocyte projection)|go:"GO:0097546"(ciliary base)|go:"GO:0098793"(presynapse)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003269(Potassium channel, inwardly rectifying, Kir1.2)|interpro:IPR013518(Potassium channel, inwardly rectifying, Kir, cytoplasmic)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR016449(Potassium channel, inwardly rectifying, Kir)|interpro:IPR040445|interpro:IPR041647|mint:Q9JM63|reactome:R-MMU-1296041|reactome:R-MMU-1296067|reactome:R-MMU-997272|hgnc:"MGI:1194504"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:xYsrr3gfPI6Dob9k78XGFz3Pp2410090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:A6H8H5	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-16737362|ensembl:ENSMUSP00000126656|ensembl:ENSMUSP00000135382|uniprotkb:E9Q5T7	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:kcnb2_mouse(display_long)|uniprotkb:Voltage-gated potassium channel subunit Kv2.2(gene name synonym)|uniprotkb:Kcnb2(gene name)|psi-mi:Kcnb2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000092083(gene)|ensembl:ENSMUST00000170146(transcript)|ensembl:ENSMUST00000175681(transcript)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR003968(Potassium channel, voltage dependent, Kv)|interpro:IPR003973(Potassium channel, voltage dependent, Kv2)|interpro:IPR005821(Ion transport)|interpro:IPR005826(Potassium channel, voltage dependent, Kv2.2)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|refseq:NP_001091998.1|refseq:XP_006495658.1|hgnc:"MGI:99632"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:TNVAivaGQKy5i3ZrUhkuzWLb7Ns10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:P62482	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-771096|uniprotkb:P97381|uniprotkb:Q60942|uniprotkb:Q64284|ensembl:ENSMUSP00000101273|ensembl:ENSMUSP00000125058	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:kcab2_mouse(display_long)|uniprotkb:"K(+) channel subunit beta-2"(gene name synonym)|uniprotkb:Kv-beta-2(gene name synonym)|uniprotkb:Neuroimmune protein F5(gene name synonym)|uniprotkb:Kcnab2(gene name)|psi-mi:Kcnab2(display_short)|uniprotkb:Ckbeta2(gene name synonym)|uniprotkb:I2rf5(gene name synonym)|uniprotkb:Kcnb3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_034728.2|refseq:XP_017175485.1|refseq:NP_001239585.1|ensembl:ENSMUSG00000028931(gene)|ensembl:ENSMUST00000105648(transcript)|ensembl:ENSMUST00000160884(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0004033"("aldo-keto reductase (NADP) activity")|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0030424"(axon)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0034705"(potassium channel complex)|go:"GO:0043005"(neuron projection)|go:"GO:0043679"(axon terminus)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047834"(D-threo-aldose 1-dehydrogenase activity)|go:"GO:0050905"(neuromuscular process)|go:"GO:0070995"(NADPH oxidation)|go:"GO:0098900"(regulation of action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1990031"(pinceau fiber)|go:"GO:2000008"(regulation of protein localization to cell surface)|interpro:IPR005399(Potassium channel, voltage-dependent, beta subunit, KCNAB-related)|interpro:IPR005401(Potassium channel, voltage-dependent, beta subunit, KCNAB2)|interpro:IPR005983(Potassium channel, voltage-dependent, beta subunit, KCNAB)|interpro:IPR023210|interpro:IPR036812|mint:P62482|reactome:R-MMU-1296072|reactome:R-MMU-6798695|hgnc:"MGI:109239"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:ZWu/Ez0ginUniSAUbIGXgod3iqg10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q61423	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-2309633|uniprotkb:Q8CBF8|ensembl:ENSMUSP00000037958	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:kcna4_mouse(display_long)|uniprotkb:Kcna4(gene name)|psi-mi:Kcna4(display_short)|uniprotkb:Voltage-gated potassium channel subunit Kv1.4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_067250.2|refseq:XP_006498875.1|ensembl:ENSMUSG00000042604(gene)|ensembl:ENSMUST00000037012(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030424"(axon)|go:"GO:0030955"(potassium ion binding)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR003968(Potassium channel, voltage dependent, Kv)|interpro:IPR003972(Potassium channel, voltage dependent, Kv1)|interpro:IPR005821(Ion transport)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR012897(Potassium channel, voltage dependent, Kv1.4, tandem inactivation)|interpro:IPR020467|interpro:IPR027359|interpro:IPR028325|interpro:IPR037065|reactome:R-MMU-1296072|hgnc:"MGI:96661"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:kLzL2QUiIqbJX3FwQ8RNPL9rxac10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q8BNW9	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-11571515|uniprotkb:A3KME3|ensembl:ENSMUSP00000068321|ensembl:ENSMUSP00000139292	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:kbtbb_mouse(display_long)|uniprotkb:Kiaa0711(gene name synonym)|uniprotkb:Kbtbd11(gene name)|psi-mi:Kbtbd11(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_083392.1|refseq:XP_006508978.1|refseq:XP_006508979.1|ensembl:ENSMUSG00000055675(gene)|ensembl:ENSMUST00000069399(transcript)|ensembl:ENSMUST00000183471(transcript)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR015915(Kelch-type beta propeller)|hgnc:"MGI:1922151"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:yLjX0Q7abh2OYDB/pJOie3k+9Ks10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:A2CG49	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865|hgnc:"MGI:2685385"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q8R071	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-400175|uniprotkb:A2AQ20|ensembl:ENSMUSP00000028758	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:ip3ka_mouse(display_long)|uniprotkb:Itpka(gene name)|psi-mi:Itpka(display_short)|uniprotkb:Inositol 1,4,5-trisphosphate 3-kinase A(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_666237.1|ensembl:ENSMUSG00000027296(gene)|ensembl:ENSMUST00000028758(transcript)|go:"GO:0000828"(inositol hexakisphosphate kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006020"(inositol metabolic process)|go:"GO:0008440"(inositol-1,4,5-trisphosphate 3-kinase activity)|go:"GO:0016301"(kinase activity)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032958"(inositol phosphate biosynthetic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0097062"(dendritic spine maintenance)|interpro:IPR005522(Inositol polyphosphate kinase)|interpro:IPR038286|mint:Q8R071|reactome:R-MMU-1855204|hgnc:"MGI:1333822"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:jbKxFPr5BAsFC6V2IFEW7U6PBcA10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q8R0S2	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-772277|uniprotkb:Q3TZC3|uniprotkb:Q5DU15|ensembl:ENSMUSP00000098712	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:iqec1_mouse(display_long)|uniprotkb:Iqsec1(gene name)|psi-mi:Iqsec1(display_short)|uniprotkb:Kiaa0763(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_001127855.1|ensembl:ENSMUSG00000034312(gene)|ensembl:ENSMUST00000101153(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008289"(lipid binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0060996"(dendritic spine development)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000904(SEC7-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023394|interpro:IPR030737|interpro:IPR033742|interpro:IPR035999|hgnc:"MGI:1196356"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:BZg7CaLndE4ak8KXs34YFf9iBRQ10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q3UQ44	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-16724715|ensembl:ENSMUSP00000067685	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:iqga2_mouse(display_long)|uniprotkb:Iqgap2(gene name)|psi-mi:Iqgap2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000021676(gene)|ensembl:ENSMUST00000068603(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005902"(microvillus)|go:"GO:0009986"(cell surface)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0070493"(thrombin-activated receptor signaling pathway)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR036872|reactome:R-MMU-5626467|reactome:R-MMU-6798695|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013408|refseq:NP_081987.1|hgnc:"MGI:2449975"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:YD6GurtWVrIzYEBzXb7fdJ6qAWI10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q9JKF1	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-644633|ensembl:ENSMUSP00000128278|uniprotkb:G3UW45	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:iqga1_mouse(display_long)|uniprotkb:Iqgap1(gene name)|psi-mi:Iqgap1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900086"(positive regulation of peptidyl-tyrosine autophosphorylation)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990776"(response to angiotensin)|ensembl:ENSMUSG00000030536(gene)|ensembl:ENSMUST00000167377(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010761"(fibroblast migration)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035305"(negative regulation of dephosphorylation)|go:"GO:0036057"(slit diaphragm)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0031252"(cell leading edge)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR027417|interpro:IPR036872|mint:Q9JKF1|reactome:R-MMU-373753|reactome:R-MMU-5626467|reactome:R-MMU-5674135|reactome:R-MMU-6798695|reactome:R-MMU-8980692|reactome:R-MMU-9013106|reactome:R-MMU-9013148|go:"GO:1990904"(ribonucleoprotein complex)|reactome:R-MMU-9013149|refseq:NP_057930.2|reactome:R-MMU-9013404|reactome:R-MMU-9013406|reactome:R-MMU-9013420|reactome:R-MMU-9013424|hgnc:"MGI:1352757"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:qjWT+er4GkLOlebk3zzRHh2Iqoo10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q9Z2Y3-3	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-16737354|ensembl:ENSMUSP00000050471	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:q9z2y3-3(display_long)|uniprotkb:VASP/Ena-related gene up-regulated during seizure and LTP 1(gene name synonym)|uniprotkb:Homer1(gene name)|psi-mi:Homer1(display_short)|uniprotkb:Vesl1(gene name synonym)|uniprotkb:1b(isoform synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000007617(gene)|ensembl:ENSMUST00000060490(transcript)|intact:EBI-396980(isoform-parent)|hgnc:"MGI:1347345"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:Mxz+XOhw/DikACZWOfsLR+D8arA10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q9WV60	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-400793|ensembl:ENSMUSP00000023507	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:gsk3b_mouse(display_long)|uniprotkb:Gsk3b(gene name)|psi-mi:Gsk3b(display_short)|uniprotkb:Serine/threonine-protein kinase GSK3B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_062801.1|dip:DIP-32446N|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006983"(ER overload response)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0007520"(myoblast fusion)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010822"(positive regulation of mitochondrion organization)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014043"(negative regulation of neuron maturation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0034452"(dynactin binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|go:"GO:2000738"(positive regulation of stem cell differentiation)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033573|interpro:IPR039192|mint:Q9WV60|rcsb pdb:4NU1|rcsb pdb:5AIR|rcsb pdb:6AE3|reactome:R-MMU-195253|reactome:R-MMU-196299|reactome:R-MMU-3371453|reactome:R-MMU-399956|reactome:R-MMU-4641262|reactome:R-MMU-5250924|reactome:R-MMU-5610785|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035733"(hepatic stellate cell activation)|go:"GO:0036016"(cellular response to interleukin-3)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043227"(membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044027"(hypermethylation of CpG island)|go:"GO:0044297"(cell body)|go:"GO:0045121"(membrane raft)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046849"(bone remodeling)|go:"GO:0048156"(tau protein binding)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071109"(superior temporal gyrus development)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090290"(positive regulation of osteoclast proliferation)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099159"(regulation of modification of postsynaptic structure)|go:"GO:0106027"(neuron projection organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0150101"(regulation of microtubule anchoring at centrosome)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1901030"(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901984"(negative regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1904339"(negative regulation of dopaminergic neuron differentiation)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904780"(negative regulation of protein localization to centrosome)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000171"(negative regulation of dendrite development)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|ensembl:ENSMUSG00000022812(gene)|ensembl:ENSMUST00000023507(transcript)|go:"GO:0000320"(re-entry into mitotic cell cycle)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|hgnc:"MGI:1861437"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:FKe0WkOBBYU0vIJLmcFNMJ+KVHA10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:E9QMC2	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-16735783|ensembl:ENSMUSP00000102884|ensembl:ENSMUSP00000118393|uniprotkb:F6WSV0	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:e9qmc2_mouse(display_long)|uniprotkb:Grm5(gene name)|psi-mi:Grm5(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000049583(gene)|ensembl:ENSMUST00000107263(transcript)|ensembl:ENSMUST00000125009(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000162(GPCR, family 3, metabotropic glutamate receptor)|interpro:IPR000202(GPCR, family 3, metabotropic glutamate receptor 5)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR011500(GPCR, family 3, nine cysteines region)|interpro:IPR017978|interpro:IPR017979|interpro:IPR019588|interpro:IPR028082|interpro:IPR038550|refseq:NP_001074883.1|hgnc:"MGI:1351342"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:j/j52EhyJy0J9a9bTS5JNjb3sbE10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q03391	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-2309422|uniprotkb:C9K0Z5|ensembl:ENSMUSP00000002848|ensembl:ENSMUSP00000147663	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:nmde4_mouse(display_long)|uniprotkb:Grin2d(gene name)|psi-mi:Grin2d(display_short)|uniprotkb:N-methyl D-aspartate receptor subtype 2D(gene name synonym)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-4(gene name synonym)|uniprotkb:GluN2D(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:XP_011249107.1|refseq:NP_032198.2|ensembl:ENSMUSG00000002771(gene)|ensembl:ENSMUST00000002848(transcript)|ensembl:ENSMUST00000211713(transcript)|go:"GO:0001964"(startle response)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016595"(glutamate binding)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0045202"(synapse)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|mint:Q03391|reactome:R-MMU-438066|reactome:R-MMU-5673001|reactome:R-MMU-8849932|reactome:R-MMU-9609736|hgnc:"MGI:95823"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:SJwi1VKUdtgh3l6xcUxHm/57loU10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q01097	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-400125|uniprotkb:Q9DCB2	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:nmde2_mouse(display_long)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-2(gene name synonym)|uniprotkb:Grin2b(gene name)|psi-mi:Grin2b(display_short)|uniprotkb:N-methyl D-aspartate receptor subtype 2B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_032197.3|go:"GO:0001508"(action potential)|go:"GO:0001662"(behavioral fear response)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001964"(startle response)|go:"GO:0001967"(suckling behavior)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005234"(extracellularly glutamate-gated ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007423"(sensory organ development)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008306"(associative learning)|go:"GO:0009986"(cell surface)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016594"(glycine binding)|go:"GO:0016595"(glutamate binding)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0030018"(Z disc)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0036094"(small molecule binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0042596"(fear response)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043113"(receptor clustering)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0044307"(dendritic branch)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0046960"(sensitization)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0048511"(rhythmic process)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099529"(neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential)|go:"GO:0099583"(neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|go:"GO:0099566"(regulation of postsynaptic cytosolic calcium ion concentration)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018884|interpro:IPR019594|interpro:IPR028082|reactome:R-MMU-3928662|reactome:R-MMU-438066|reactome:R-MMU-5673001|reactome:R-MMU-8849932|reactome:R-MMU-9609736|mint:Q01097|dip:DIP-31568N|hgnc:"MGI:95821"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:SvjoNuuHCFT+Yj1woYrEvU6n8B010090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:P35436	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-400115|ensembl:ENSMUSP00000032331|ensembl:ENSMUSP00000111501|ensembl:ENSMUSP00000142900	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:nmde1_mouse(display_long)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-1(gene name synonym)|uniprotkb:Grin2a(gene name)|psi-mi:Grin2a(display_short)|uniprotkb:N-methyl D-aspartate receptor subtype 2A(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_032196.2|reactome:R-MMU-8849932|reactome:R-MMU-9609736|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099507"(ligand-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:1903539"(protein localization to postsynaptic membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018884|interpro:IPR019594|interpro:IPR028082|reactome:R-MMU-438066|go:"GO:0098839"(postsynaptic density membrane)|ensembl:ENSMUSG00000059003(gene)|ensembl:ENSMUST00000032331(transcript)|ensembl:ENSMUST00000115835(transcript)|ensembl:ENSMUST00000199708(transcript)|go:"GO:0001508"(action potential)|go:"GO:0001964"(startle response)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0030431"(sleep)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0033058"(directional locomotion)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040011"(locomotion)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042428"(serotonin metabolic process)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048511"(rhythmic process)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|refseq:XP_006521857.1|dip:DIP-31567N|hgnc:"MGI:95820"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:5DMFDOh6NuFArDtKp2gp2IpmhWQ10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:A2AI21	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-2309370|ensembl:ENSMUSP00000109949	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:a2ai21_mouse(display_long)|uniprotkb:Grin1(gene name)|psi-mi:Grin1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:XP_006497785.1|ensembl:ENSMUSG00000026959(gene)|ensembl:ENSMUST00000114310(transcript)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0016594"(glycine binding)|go:"GO:0016595"(glutamate binding)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0030425"(dendrite)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:1905429"(response to glycine)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018882|interpro:IPR019594|interpro:IPR028082|hgnc:"MGI:95819"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:VE/Fb1yWDHyjJEm0UZWwXa9pKj810090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q9Z2W9	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-445507|uniprotkb:A2VDF4|uniprotkb:Q5DTJ0|ensembl:ENSMUSP00000075687	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:gria3_mouse(display_long)|uniprotkb:GluR-K3(gene name synonym)|uniprotkb:Glutamate receptor ionotropic, AMPA 3(gene name synonym)|uniprotkb:AMPA-selective glutamate receptor 3(gene name synonym)|uniprotkb:Gria3(gene name)|psi-mi:Gria3(display_short)|uniprotkb:Kiaa4184(gene name synonym)|uniprotkb:Glur3(gene name synonym)|uniprotkb:GluR-C(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_058582.3|refseq:XP_006541583.1|refseq:NP_001268858.1|refseq:XP_017174034.1|ensembl:ENSMUSG00000001986(gene)|ensembl:ENSMUST00000076349(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004971"(AMPA glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032991"(protein-containing complex)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|go:"GO:0038023"(signaling receptor activity)|interpro:IPR028082|go:"GO:0043025"(neuronal cell body)|mint:Q9Z2W9|rcsb pdb:3LSW|rcsb pdb:3LSX|go:"GO:0043083"(synaptic cleft)|reactome:R-MMU-399710|reactome:R-MMU-399719|reactome:R-MMU-416993|go:"GO:0043195"(terminal bouton)|reactome:R-MMU-438066|go:"GO:0043197"(dendritic spine)|reactome:R-MMU-8849932|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001320(Ionotropic glutamate receptor)|hgnc:"MGI:95810"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:n9Lnq/kl4co4Th5d/N5JX+cN4yU10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:P23819	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-77538|uniprotkb:Q61604|uniprotkb:Q61605|uniprotkb:Q8BG69|uniprotkb:Q8BXU3|uniprotkb:Q9D6D3	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:gria2_mouse(display_long)|uniprotkb:Gria2(gene name)|psi-mi:Gria2(display_short)|uniprotkb:Glur2(gene name synonym)|uniprotkb:GluR-B(gene name synonym)|uniprotkb:GluR-K2(gene name synonym)|uniprotkb:Glutamate receptor ionotropic, AMPA 2(gene name synonym)|uniprotkb:AMPA-selective glutamate receptor 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051117"(ATPase binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099544"(perisynaptic space)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|reactome:R-MMU-399710|reactome:R-MMU-416993|reactome:R-MMU-438066|go:"GO:0000149"(SNARE binding)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004971"(AMPA glutamate receptor activity)|go:"GO:0005234"(extracellularly glutamate-gated ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0015277"(kainate selective glutamate receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031623"(receptor internalization)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|interpro:IPR028082|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|mint:P23819|hgnc:"MGI:95809"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:v71xzThz9kadLOPBasVAc1y/FXs10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:P23818	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-445486|ensembl:ENSMUSP00000044494	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:gria1_mouse(display_long)|uniprotkb:GluR-A(gene name synonym)|uniprotkb:GluR-K1(gene name synonym)|uniprotkb:Glutamate receptor ionotropic, AMPA 1(gene name synonym)|uniprotkb:AMPA-selective glutamate receptor 1(gene name synonym)|uniprotkb:Gria1(gene name)|psi-mi:Gria1(display_short)|uniprotkb:Glur1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_001106796.1|dip:DIP-31970N|go:"GO:0005911"(cell-cell junction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044297"(cell body)|go:"GO:0007616"(long-term memory)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009986"(cell surface)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0044308"(axonal spine)|go:"GO:0044309"(neuron spine)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045838"(positive regulation of membrane potential)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060076"(excitatory synapse)|go:"GO:0045202"(synapse)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0071242"(cellular response to ammonium ion)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099544"(perisynaptic space)|go:"GO:0099583"(neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|rcsb pdb:7LDD|rcsb pdb:7LDE|reactome:R-MMU-204005|reactome:R-MMU-399710|reactome:R-MMU-399719|reactome:R-MMU-416993|ensembl:ENSMUSG00000020524(gene)|ensembl:ENSMUST00000036315(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004971"(AMPA glutamate receptor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|reactome:R-MMU-438066|reactome:R-MMU-5694530|reactome:R-MMU-8849932|hgnc:"MGI:95808"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:5hAcAV1UEfdgn7CNrrAHPIwUs/410090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:D3Z1M1	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-16737338|ensembl:ENSMUSP00000119725	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:d3z1m1_mouse(display_long)|uniprotkb:Gnb2(gene name)|psi-mi:Gnb2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000029713(gene)|ensembl:ENSMUST00000132525(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|hgnc:"MGI:95784"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:cCSiiHdjnuu7FrkyTKZUf+1OSk410090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:H3BKR2	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-16737316|ensembl:ENSMUSP00000135492	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:h3bkr2_mouse(display_long)|uniprotkb:Gnb1(gene name)|psi-mi:Gnb1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000029064(gene)|ensembl:ENSMUST00000177094(transcript)|go:"GO:0007165"(signal transduction)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|hgnc:"MGI:95781"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:zljiVvSkw2TfsEdz9deDCbBPyw410090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:O70443	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-771994|uniprotkb:O70442|uniprotkb:Q61637|uniprotkb:Q91WM4|ensembl:ENSMUSP00000036087|ensembl:ENSMUSP00000124639	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:gnaz_mouse(display_long)|uniprotkb:"G(x) alpha chain"(gene name synonym)|uniprotkb:Gz-alpha(gene name synonym)|uniprotkb:Gnaz(gene name)|psi-mi:Gnaz(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_034441.1|refseq:XP_006513299.1|refseq:XP_006513300.1|refseq:XP_006513298.1|ensembl:ENSMUSG00000040009(gene)|ensembl:ENSMUST00000037813(transcript)|ensembl:ENSMUST00000159991(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|go:"GO:0044297"(cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0098664"(G protein-coupled serotonin receptor signaling pathway)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:O70443|reactome:R-MMU-418597|hgnc:"MGI:95780"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:tIlKib9CoNSvCkb2TvLU/QwdCYk10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:P63094-2	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-16735734|ensembl:ENSMUSP00000104713	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:p63094-2(display_long)|uniprotkb:Adenylate cyclase-stimulating G alpha protein(gene name synonym)|uniprotkb:Gnas(gene name)|psi-mi:Gnas(display_short)|uniprotkb:Gnas1(gene name synonym)|uniprotkb:MNCb-5546(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000027523(gene)|ensembl:ENSMUST00000109085(transcript)|intact:EBI-444709(isoform-parent)|hgnc:"MGI:95777"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:ulzhJCkFKuk6kfFAB/JlrwYDSdM10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:P18872	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-771950|uniprotkb:P18873|intact:EBI-1018769|ensembl:ENSMUSP00000034198|ensembl:ENSMUSP00000114144	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:gnao_mouse(display_long)|uniprotkb:Gnao1(gene name)|psi-mi:Gnao1(display_short)|uniprotkb:Gna0(gene name synonym)|uniprotkb:Gnao(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_001106855.1|refseq:NP_034438.1|dip:DIP-29921N|ensembl:ENSMUSG00000031748(gene)|ensembl:ENSMUST00000034198(transcript)|ensembl:ENSMUST00000125716(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0007568"(aging)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0009987"(cellular process)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030900"(forebrain development)|go:"GO:0031175"(neuron projection development)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034097"(response to cytokine)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043005"(neuron projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0043278"(response to morphine)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044297"(cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0051430"(corticotropin-releasing hormone receptor 1 binding)|go:"GO:0051926"(negative regulation of calcium ion transport)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P18872|rcsb pdb:3C7K|reactome:R-MMU-4086398|hgnc:"MGI:95775"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:CCww9l5owYxGicswRXjsSu6Y+5g10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:P15105	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-444858|uniprotkb:Q3TRK7|uniprotkb:Q64432|uniprotkb:Q91VC6|ensembl:ENSMUSP00000083375|ensembl:ENSMUSP00000123157	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:glna_mouse(display_long)|uniprotkb:Glutamate--ammonia ligase(gene name synonym)|uniprotkb:Glul(gene name)|psi-mi:Glul(display_short)|uniprotkb:Glns(gene name synonym)|uniprotkb:Palmitoyltransferase GLUL(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_032157.2|go:"GO:0030145"(manganese ion binding)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043679"(axon terminus)|go:"GO:0044297"(cell body)|go:"GO:0045503"(dynein light chain binding)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0097386"(glial cell projection)|go:"GO:1903670"(regulation of sprouting angiogenesis)|go:"GO:1904749"(regulation of protein localization to nucleolus)|interpro:IPR008146(Glutamine synthetase, catalytic region)|interpro:IPR008147(Glutamine synthetase, beta-Grasp)|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR027302|interpro:IPR027303|interpro:IPR036651|mint:P15105|reactome:R-MMU-210455|reactome:R-MMU-8964539|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|ensembl:ENSMUSG00000026473(gene)|ensembl:ENSMUST00000086199(transcript)|ensembl:ENSMUST00000140685(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0004356"(glutamate-ammonia ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0006542"(glutamine biosynthetic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009749"(response to glucose)|go:"GO:0010594"(regulation of endothelial cell migration)|go:"GO:0016595"(glutamate binding)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019676"(ammonia assimilation cycle)|hgnc:"MGI:95739"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:j6R9fxGLKpiREWpecpdnBY9ftoo10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q68FF6	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-645933|ensembl:ENSMUSP00000037210	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:git1_mouse(display_long)|uniprotkb:G protein-coupled receptor kinase-interactor 1(gene name synonym)|uniprotkb:GRK-interacting protein 1(gene name synonym)|uniprotkb:Git1(gene name)|psi-mi:Git1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_001004144.1|ensembl:ENSMUSG00000011877(gene)|ensembl:ENSMUST00000037285(transcript)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001957"(intramembranous ossification)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007420"(brain development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030027"(lamellipodium)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032013"(negative regulation of ARF protein signal transduction)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0044305"(calyx of Held)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048666"(neuron development)|go:"GO:0060996"(dendritic spine development)|go:"GO:0061743"(motor learning)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0098794"(postsynapse)|go:"GO:0098879"(structural constituent of postsynaptic specialization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099171"(presynaptic modulation of chemical synaptic transmission)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106015"(negative regulation of inflammatory response to wounding)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000646"(positive regulation of receptor catabolic process)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR002110(Ankyrin)|interpro:IPR013724("Spa2 homology (SHD) of GIT")|interpro:IPR020683|interpro:IPR022018|interpro:IPR032352|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|mint:Q68FF6|rcsb pdb:6JMU|reactome:R-MMU-3928664|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013406|reactome:R-MMU-9013420|reactome:R-MMU-9013423|reactome:R-MMU-9013424|hgnc:"MGI:1927140"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:3br9Xz6GZQV409u3u7CZDfqKMIM10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q61598	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-6665490|ensembl:ENSMUSP00000152454|uniprotkb:Q541Z9|uniprotkb:Q8C530|uniprotkb:Q9D8M9	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:gdib_mouse(display_long)|uniprotkb:Gdi2(gene name)|psi-mi:Gdi2(display_short)|uniprotkb:Gdi3(gene name synonym)|uniprotkb:GDI-3(gene name synonym)|uniprotkb:Guanosine diphosphate dissociation inhibitor 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045202"(synapse)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|mint:Q61598|reactome:R-MMU-6798695|reactome:R-MMU-8876198|ensembl:ENSMUSG00000021218(gene)|ensembl:ENSMUST00000223396(transcript)|refseq:NP_032138.3|dip:DIP-348N|hgnc:"MGI:99845"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:+ngZz9q02lDEdFO543w/yl6chgc10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q9R111	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-2308876|ensembl:ENSMUSP00000084882	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:guad_mouse(display_long)|uniprotkb:Gda(gene name)|psi-mi:Gda(display_short)|uniprotkb:Guanine aminohydrolase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_034396.1|ensembl:ENSMUSG00000058624(gene)|ensembl:ENSMUST00000087600(transcript)|go:"GO:0000255"(allantoin metabolic process)|go:"GO:0005829"(cytosol)|go:"GO:0006147"(guanine catabolic process)|go:"GO:0006161"(deoxyguanosine catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008892"(guanine deaminase activity)|go:"GO:0019239"(deaminase activity)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0046055"(dGMP catabolic process)|go:"GO:0046098"(guanine metabolic process)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR014311(Guanine deaminase)|interpro:IPR032466|mint:Q9R111|reactome:R-MMU-74259|go:"GO:0046038"(GMP catabolic process)|hgnc:"MGI:95678"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:4GljtxkNduzgstV1OX/vkPJ/Qvg10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q80UW2	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-2314714|uniprotkb:Q8R0D2|ensembl:ENSMUSP00000037377	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:fbx2_mouse(display_long)|uniprotkb:Fbs1(gene name synonym)|uniprotkb:Fbxo2(gene name)|psi-mi:Fbxo2(display_short)|uniprotkb:Fbx2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_789818.1|refseq:XP_006538877.1|dip:DIP-54758N|ensembl:ENSMUSG00000041556(gene)|ensembl:ENSMUST00000047951(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006516"(glycoprotein catabolic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0043197"(dendritic spine)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007397(F-box associated region)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036047|interpro:IPR039752|rcsb pdb:1UMH|rcsb pdb:1UMI|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2E33|rcsb pdb:2RJ2|rcsb pdb:5B4N|reactome:R-MMU-8951664|reactome:R-MMU-983168|hgnc:"MGI:2446216"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:MFGKJfNmB58nx1Ij634RZe95br010090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q3UXZ6	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-2308826|uniprotkb:Q8BQV1|uniprotkb:Q8C548|uniprotkb:Q8R3B5|uniprotkb:Q9D369|ensembl:ENSMUSP00000034749	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:fa81a_mouse(display_long)|uniprotkb:Fam81a(gene name)|psi-mi:Fam81a(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_084060.1|refseq:XP_006511613.1|refseq:XP_006511614.1|ensembl:ENSMUSG00000032224(gene)|ensembl:ENSMUST00000034749(transcript)|interpro:IPR029619|interpro:IPR029622|hgnc:"MGI:1924136"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:B2gqwbO+APP0oh2e0om4bCpv7UM10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:O70318	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-643339|uniprotkb:G3X9B8|ensembl:ENSMUSP00000055122|ensembl:ENSMUSP00000090314	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:e41l2_mouse(display_long)|uniprotkb:Generally expressed protein 4.1(gene name synonym)|uniprotkb:Epb41l2(gene name)|psi-mi:Epb41l2(display_short)|uniprotkb:Epb4.1l2(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 4.1-like 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_038539.2|refseq:NP_001186194.1|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0005654"(nucleoplasm)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030507"(spectrin binding)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0042731"(PH domain binding)|go:"GO:0051301"(cell division)|go:"GO:0099738"(cell cortex region)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR007477(SAB)|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030546|interpro:IPR035963|mint:O70318|reactome:R-MMU-6794361|ensembl:ENSMUSG00000019978(gene)|ensembl:ENSMUST00000053748(transcript)|ensembl:ENSMUST00000092645(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|hgnc:"MGI:103009"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:4hNttT3WQk43puSMmOdjpNS8oUo10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q9JHU4	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-645061|uniprotkb:E9QM71|ensembl:ENSMUSP00000018851	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:dyhc1_mouse(display_long)|uniprotkb:Dhc1(gene name synonym)|uniprotkb:Dyhc(gene name synonym)|uniprotkb:Cytoplasmic dynein heavy chain 1(gene name synonym)|uniprotkb:Dynein heavy chain, cytosolic(gene name synonym)|uniprotkb:Dync1h1(gene name)|psi-mi:Dync1h1(display_short)|uniprotkb:Dnch1(gene name synonym)|uniprotkb:Dnchc1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_084514.2|ensembl:ENSMUSG00000018707(gene)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002177"(manchette)|go:"GO:0003341"(cilium movement)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007097"(nuclear migration)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008569"(minus-end-directed microtubule motor activity)|go:"GO:0030175"(filopodium)|go:"GO:0030286"(dynein complex)|go:"GO:0030424"(axon)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051301"(cell division)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072382"(minus-end-directed vesicle transport along microtubule)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004273(Dynein heavy chain)|interpro:IPR013594(Dynein heavy chain, N-terminal region 1)|interpro:IPR013602(Dynein heavy chain, N-terminal region 2)|interpro:IPR024317|interpro:IPR024743|interpro:IPR027417|interpro:IPR035699|interpro:IPR035706|interpro:IPR041228|interpro:IPR041466|interpro:IPR041658|ensembl:ENSMUST00000018851(transcript)|interpro:IPR042222|interpro:IPR042228|interpro:IPR043157|interpro:IPR043160|interpro:IPR042219|mint:Q9JHU4|rcsb pdb:3ERR|rcsb pdb:3J1T|rcsb pdb:3J1U|rcsb pdb:3WUQ|rcsb pdb:5AYH|rcsb pdb:6RZA|rcsb pdb:6RZB|reactome:R-MMU-141444|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-6798695|reactome:R-MMU-6807878|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9646399|reactome:R-MMU-9648025|hgnc:"MGI:103147"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:sbED0xqQpe32T7I8ijeS3Xqlx7010090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:O08553	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-446064|uniprotkb:Q6P5D0|ensembl:ENSMUSP00000022629	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:dpyl2_mouse(display_long)|uniprotkb:Unc-33-like phosphoprotein 2(gene name synonym)|uniprotkb:Dpysl2(gene name)|psi-mi:Dpysl2(display_short)|uniprotkb:Crmp2(gene name synonym)|uniprotkb:Ulip2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_034085.2|ensembl:ENSMUSG00000022048(gene)|ensembl:ENSMUST00000022629(transcript)|go:"GO:0001975"(response to amphetamine)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0019901"(protein kinase binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043209"(myelin sheath)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0098793"(presynapse)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011778(D-hydantoinase)|interpro:IPR030615|interpro:IPR032466|mint:O08553|rcsb pdb:5UQC|reactome:R-MMU-399956|reactome:R-MMU-437239|hgnc:"MGI:1349763"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:97yc8TNEPMcGtGNRLvl+KV+DYr010090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q8K1M6	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-2365792|uniprotkb:Q8BNQ5|uniprotkb:Q8BQ64|uniprotkb:Q8CGD0|uniprotkb:Q8K1A1	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:dnm1l_mouse(display_long)|uniprotkb:Dnm1l(gene name)|psi-mi:Dnm1l(display_short)|uniprotkb:Drp1(gene name synonym)|uniprotkb:Dynamin-related protein 1(gene name synonym)|uniprotkb:Dynamin family member proline-rich carboxyl-terminal domain less(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_001021118.1|refseq:XP_006522694.1|refseq:NP_001263269.1|refseq:NP_001263270.1|refseq:NP_690029.2|dip:DIP-54818N|mint:Q8K1M6|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0030276"(clathrin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036466"(synaptic vesicle recycling via endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048511"(rhythmic process)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051433"(BH2 domain binding)|go:"GO:0060047"(heart contraction)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070266"(necroptotic process)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090149"(mitochondrial membrane fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099503"(secretory vesicle)|go:"GO:1900063"(regulation of peroxisome organization)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903578"(regulation of ATP metabolic process)|go:"GO:1904579"(cellular response to thapsigargin)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1905395"(response to flavonoid)|go:"GO:1990910"(response to hypobaric hypoxia)|go:"GO:2000302"(positive regulation of synaptic vesicle exocytosis)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR030556|reactome:R-MMU-75153|go:"GO:0005903"(brush border)|hgnc:"MGI:1921256"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:5yGX3+QNfz3+dKRHA2ffkIVq3yU10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:P39053-4	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-397818|ensembl:ENSMUSP00000108992	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:p39053-4(display_long)|uniprotkb:BraDnm2(isoform synonym)|uniprotkb:Dnm1(gene name)|psi-mi:Dnm1(display_short)|uniprotkb:Dnm(gene name synonym)|uniprotkb:Kiaa4093(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000026825(gene)|ensembl:ENSMUST00000113365(transcript)|intact:EBI-397785(dyn1_mouse)|uniprotkb:P39053-4(isoform-parent)|hgnc:"MGI:107384"(identity)	go:"GO:0014069"(postsynaptic density)	-	isoform-comment:Contains a phosphoserine at position 857. Contains a phosphoserine at position 851.	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:0CuiBEwyXQkP152WfUuPUjJDAzE10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q8BPN8	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-6272744|ensembl:ENSMUSP00000113693|uniprotkb:B0V2P4|uniprotkb:Q3TNY5|uniprotkb:Q69ZX5|uniprotkb:Q8CCU3	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:dmxl2_mouse(display_long)|uniprotkb:Dmxl2(gene name)|psi-mi:Dmxl2(display_short)|uniprotkb:Kiaa0856(gene name synonym)|uniprotkb:Rabconnectin-3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000041268(gene)|ensembl:ENSMUST00000118600(transcript)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043291"(RAVE complex)|go:"GO:0098992"(neuronal dense core vesicle)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR022033|interpro:IPR036322|mint:Q8BPN8|go:"GO:0007283"(spermatogenesis)|refseq:XP_006511148.2|hgnc:"MGI:2444630"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:6uQuMnUYqGc8AF3fTtUWEHX2Z1w10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:B1AZP2-2	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-1876723|ensembl:ENSMUSP00000068745|ensembl:ENSMUSP00000105195	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:b1azp2-2(display_long)|uniprotkb:Dlgap4(gene name)|psi-mi:Dlgap4(display_short)|uniprotkb:Kiaa0964(gene name synonym)|uniprotkb:Sapap4(gene name synonym)|uniprotkb:PSD-95/SAP90-binding protein 4(gene name synonym)|uniprotkb:SAP90/PSD-95-associated protein 4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	intact:EBI-645637(isoform-parent)|ensembl:ENSMUSG00000061689(gene)|ensembl:ENSMUST00000070782(transcript)|ensembl:ENSMUST00000109567(transcript)|uniprotkb:B1AZP2-2(isoform-parent)|hgnc:"MGI:2138865"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:sZ1V4zl/sR4a3PxzMg8iE8w6rSE10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:B1AS06	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-16735681|ensembl:ENSMUSP00000101698	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:b1as06_mouse(display_long)|uniprotkb:Dlgap3(gene name)|psi-mi:Dlgap3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000042388(gene)|ensembl:ENSMUST00000106092(transcript)|go:"GO:0023052"(signaling)|interpro:IPR005026(Guanylate-kinase-associated protein)|interpro:IPR030526|refseq:XP_006503167.1|hgnc:"MGI:3039563"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:bIEDbBzjulDcrYVDgPsjiNsH7i010090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q8BJ42	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-2308675|uniprotkb:Q6XBF3|ensembl:ENSMUSP00000039647|ensembl:ENSMUSP00000119613	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:dlgp2_mouse(display_long)|uniprotkb:Dlgap2(gene name)|psi-mi:Dlgap2(display_short)|uniprotkb:Dap2(gene name synonym)|uniprotkb:SAP90/PSD-95-associated protein 2(gene name synonym)|uniprotkb:PSD-95/SAP90-binding protein 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_001139437.1|refseq:NP_766498.2|refseq:XP_017168275.1|ensembl:ENSMUSG00000047495(gene)|ensembl:ENSMUST00000043279(transcript)|ensembl:ENSMUST00000133298(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099572"(postsynaptic specialization)|interpro:IPR005026(Guanylate-kinase-associated protein)|interpro:IPR030525|reactome:R-MMU-6794361|hgnc:"MGI:2443181"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:9V3GlRM3AupA70mmFtZ4biXuC9E10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q3UVU8	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-16736804|ensembl:ENSMUSP00000094890	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:q3uvu8_mouse(display_long)|uniprotkb:Dlgap1(gene name)|psi-mi:Dlgap1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000003279(gene)|ensembl:ENSMUST00000097288(transcript)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0045202"(synapse)|interpro:IPR005026(Guanylate-kinase-associated protein)|interpro:IPR030524|refseq:NP_001121653.1|hgnc:"MGI:1346065"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:u4/fQ+K2NGlUOTQxRoYgNqaA3tA10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q62108	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-300895|ensembl:ENSMUSP00000104229|uniprotkb:Q5NCV5|uniprotkb:Q5NCV6|uniprotkb:Q5NCV7|uniprotkb:Q91WJ1	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:dlg4_mouse(display_long)|uniprotkb:Dlg4(gene name)|psi-mi:Dlg4(display_short)|uniprotkb:Dlgh4(gene name synonym)|uniprotkb:Psd95(gene name synonym)|uniprotkb:Postsynaptic density protein 95(gene name synonym)|uniprotkb:Synapse-associated protein 90(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000020886(gene)|ensembl:ENSMUST00000108588(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0019894"(kinesin binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031812"(P2Y1 nucleotide receptor binding)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0035176"(social behavior)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071625"(vocalization behavior)|go:"GO:0071944"(cell periphery)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097109"(neuroligin family protein binding)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|go:"GO:0060076"(excitatory synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|mint:Q62108|reactome:R-MMU-399719|reactome:R-MMU-438066|reactome:R-MMU-451308|reactome:R-MMU-5625900|reactome:R-MMU-5673001|reactome:R-MMU-5682910|reactome:R-MMU-6794361|reactome:R-MMU-8849932|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|refseq:NP_001103222.1|refseq:NP_031890.1|dip:DIP-29888N|hgnc:"MGI:1277959"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:9Ylvs2goE8Z/6ff4AqFCEKrPanY10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:P70175	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-396969|ensembl:ENSMUSP00000085299	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:dlg3_mouse(display_long)|uniprotkb:Dlg3(gene name)|psi-mi:Dlg3(display_short)|uniprotkb:Dlgh3(gene name synonym)|uniprotkb:Synapse-associated protein 102(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_058027.1|refseq:NP_001171249.1|ensembl:ENSMUSG00000000881(gene)|ensembl:ENSMUST00000087984(transcript)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030426"(growth cone)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR035763|interpro:IPR036028|interpro:IPR036034|mint:P70175|reactome:R-MMU-438066|reactome:R-MMU-451308|reactome:R-MMU-5673001|reactome:R-MMU-6794361|reactome:R-MMU-8849932|dip:DIP-31585N|hgnc:"MGI:1888986"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:9dR9P876v8QcvPinxtaWzDgpHwE10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q91XM9	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-400138|uniprotkb:Q8BXK7|uniprotkb:Q8BYG5|ensembl:ENSMUSP00000102814|uniprotkb:F8VQM7	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:dlg2_mouse(display_long)|uniprotkb:Dlg2(gene name)|psi-mi:Dlg2(display_short)|uniprotkb:Postsynaptic density protein PSD-93(gene name synonym)|uniprotkb:Channel-associated protein of synapse-110(gene name synonym)|uniprotkb:Dlgh2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000052572(gene)|ensembl:ENSMUST00000107196(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043204"(perikaryon)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:0099642"(retrograde axonal protein transport)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR035759|interpro:IPR036028|interpro:IPR036034|mint:Q91XM9|rcsb pdb:2WL7|reactome:R-MMU-438066|reactome:R-MMU-5673001|reactome:R-MMU-6794361|refseq:NP_001229976.1|refseq:NP_035937.2|dip:DIP-31569N|hgnc:"MGI:1344351"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:37/IFbjDNxh87dnN2gglIgDGyIU10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q811D0	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-514290|uniprotkb:Q62402|uniprotkb:Q6PGB5|uniprotkb:Q8CGN7|ensembl:ENSMUSP00000097581|ensembl:ENSMUSP00000110859	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:dlg1_mouse(display_long)|uniprotkb:Synapse-associated protein 97(gene name synonym)|uniprotkb:Embryo-dlg/synapse-associated protein 97(gene name synonym)|uniprotkb:Dlg1(gene name)|psi-mi:Dlg1(display_short)|uniprotkb:Dlgh1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_031888.2|refseq:NP_001239362.1|refseq:NP_001239364.1|refseq:XP_006521831.1|refseq:NP_001239363.1|dip:DIP-31591N|ensembl:ENSMUSG00000022770(gene)|ensembl:ENSMUST00000100001(transcript)|ensembl:ENSMUST00000115205(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0030432"(peristalsis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033270"(paranode region of axon)|go:"GO:0034629"|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043219"(lateral loop)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048729"(tissue morphogenesis)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060022"(hard palate development)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1902473"(regulation of protein localization to synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903286"(regulation of potassium ion import)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903760"(regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903764"(regulation of potassium ion export across plasma membrane)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:Q811D0|rcsb pdb:4OAJ|reactome:R-MMU-399719|reactome:R-MMU-438066|reactome:R-MMU-451308|reactome:R-MMU-5673001|reactome:R-MMU-8849932|hgnc:"MGI:107231"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:b8LjYbiuR2K6/jxhwU1hxBJKX6410090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q80UP3	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-971774|uniprotkb:A2AHJ6|ensembl:ENSMUSP00000028667	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:dgkz_mouse(display_long)|uniprotkb:Dgkz(gene name)|psi-mi:Dgkz(display_short)|uniprotkb:Diglyceride kinase zeta(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000040479(gene)|ensembl:ENSMUST00000028667(transcript)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046339"(diacylglycerol metabolic process)|go:"GO:0046486"(glycerolipid metabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046834"(lipid phosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0090216"(positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|interpro:IPR000756(Diacylglycerol kinase accessory region)|interpro:IPR001206(Diacylglycerol kinase, catalytic region)|interpro:IPR002110(Ankyrin)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|interpro:IPR020683|interpro:IPR036770|reactome:R-MMU-114508|interpro:IPR037607|go:"GO:0001727"(lipid kinase activity)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0004143"(diacylglycerol kinase activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006654"(phosphatidic acid biosynthetic process)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016301"(kinase activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0030027"(lamellipodium)|refseq:NP_612179.2|hgnc:"MGI:1278339"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:Q+JMToiGaqYHQn4Hk9FpJihw7XM10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q80TS7	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-16725318|ensembl:ENSMUSP00000074895|uniprotkb:Q3TPT2|uniprotkb:Q3TY46	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:dend_mouse(display_long)|uniprotkb:Ddn(gene name)|psi-mi:Ddn(display_short)|uniprotkb:Gm748(gene name synonym)|uniprotkb:Kiaa0749(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000059213(gene)|ensembl:ENSMUST00000075444(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0042995"(cell projection)|go:"GO:0043204"(perikaryon)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR026500|rcsb pdb:6J69|rcsb pdb:6JJZ|rcsb pdb:6JK0|rcsb pdb:6JK1|rcsb pdb:6KKG|rcsb pdb:7BQG|refseq:NP_001013763.1|hgnc:"MGI:108101"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:XTb8iMdZY6ldSiQVXuwx2ofQeVs10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q9QXS6	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-445208|uniprotkb:A2CG16|uniprotkb:Q3V234|uniprotkb:Q922X1|uniprotkb:Q9QXS5|ensembl:ENSMUSP00000021950	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:dreb_mouse(display_long)|uniprotkb:Developmentally-regulated brain protein(gene name synonym)|uniprotkb:Dbn1(gene name)|psi-mi:Dbn1(display_short)|uniprotkb:Drba(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_001170842.1|refseq:NP_001170843.1|refseq:NP_062787.2|ensembl:ENSMUSG00000034675(gene)|ensembl:ENSMUST00000021950(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005921"(gap junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0010643"(cell communication by chemical coupling)|go:"GO:0010644"(cell communication by electrical coupling)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032507"(maintenance of protein location in cell)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044308"(axonal spine)|go:"GO:0044309"(neuron spine)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048699"(generation of neurons)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090327"(negative regulation of locomotion involved in locomotory behavior)|go:"GO:0098828"(modulation of inhibitory postsynaptic potential)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0120080"(obsolete negative regulation of microfilament motor activity)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902685"(positive regulation of receptor localization to synapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:1902897"(regulation of postsynaptic density protein 95 clustering)|go:"GO:1904113"(negative regulation of muscle filament sliding)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR028438|interpro:IPR029006|mint:Q9QXS6|reactome:R-MMU-9013405|reactome:R-MMU-9013407|reactome:R-MMU-9013418|reactome:R-MMU-9013422|hgnc:"MGI:1931838"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:ArZUGZNIUfSwoIketPcPCXlSM8410090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q5SQX6	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-773783|uniprotkb:Q3UH21|uniprotkb:Q3UHS8|uniprotkb:Q8BSW0|uniprotkb:Q8CHA9|uniprotkb:Q924D3|uniprotkb:Q9R181|ensembl:ENSMUSP00000090853|ensembl:ENSMUSP00000090854|ensembl:ENSMUSP00000127586	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:cyfp2_mouse(display_long)|uniprotkb:p53-inducible protein 121(gene name synonym)|uniprotkb:Cyfip2(gene name)|psi-mi:Cyfip2(display_short)|uniprotkb:Kiaa1168(gene name synonym)|uniprotkb:Pir121(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_598530.2|refseq:NP_001239388.1|refseq:NP_001239389.1|dip:DIP-32111N|ensembl:ENSMUSG00000020340(gene)|ensembl:ENSMUST00000093165(transcript)|ensembl:ENSMUST00000093166(transcript)|ensembl:ENSMUST00000165599(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031209"(SCAR complex)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051388"(positive regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0097484"(dendrite extension)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR008081(Cytoplasmic FMR1-interacting)|interpro:IPR009828(Protein of unknown function DUF1394)|reactome:R-MMU-2029482|reactome:R-MMU-4420097|reactome:R-MMU-5663213|reactome:R-MMU-9013149|hgnc:"MGI:1924134"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:NP2S3AEcTj9DHTiDHEVM51b8jrE10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q7TMB8	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-772928|uniprotkb:Q3U7Q7|uniprotkb:Q5DU50|uniprotkb:Q7TSZ5|uniprotkb:Q80VN6|uniprotkb:Q8CE85|uniprotkb:Q99LY1|uniprotkb:O88558|ensembl:ENSMUSP00000032629|ensembl:ENSMUSP00000127717	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:cyfp1_mouse(display_long)|uniprotkb:Cyfip1(gene name)|psi-mi:Cyfip1(display_short)|uniprotkb:Shyc(gene name synonym)|uniprotkb:Kiaa0068(gene name synonym)|uniprotkb:Sra1(gene name synonym)|uniprotkb:Specifically Rac1-associated protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_001158134.1|refseq:NP_035500.2|refseq:NP_001158133.1|refseq:XP_006540792.1|ensembl:ENSMUSG00000030447(gene)|ensembl:ENSMUST00000032629(transcript)|ensembl:ENSMUST00000163845(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0007411"(axon guidance)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031175"(neuron projection development)|go:"GO:0031209"(SCAR complex)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031529"(ruffle organization)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032433"(filopodium tip)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045202"(synapse)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050890"(cognition)|go:"GO:0051015"(actin filament binding)|go:"GO:0051388"(positive regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0060076"(excitatory synapse)|go:"GO:0090724"(central region of growth cone)|go:"GO:0090725"(peripheral region of growth cone)|go:"GO:0097484"(dendrite extension)|go:"GO:0098794"(postsynapse)|go:"GO:0099563"(modification of synaptic structure)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900029"(positive regulation of ruffle assembly)|go:"GO:1903422"(negative regulation of synaptic vesicle recycling)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR008081(Cytoplasmic FMR1-interacting)|interpro:IPR009828(Protein of unknown function DUF1394)|mint:Q7TMB8|reactome:R-MMU-2029482|reactome:R-MMU-4420097|reactome:R-MMU-5663213|reactome:R-MMU-6798695|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013408|reactome:R-MMU-9013423|hgnc:"MGI:1338801"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:u8cObqx85DIdhPYtV2YWyOao3KE10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q9JLV5	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-2551335|ensembl:ENSMUSP00000130738	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:cul3_mouse(display_long)|uniprotkb:Cul3(gene name)|psi-mi:Cul3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000004364(gene)|ensembl:ENSMUST00000163119(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000922"(spindle pole)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001831"(trophectodermal cellular morphogenesis)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005112"(Notch binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005827"(polar microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007369"(gastrulation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017145"(stem cell division)|go:"GO:0030332"(cyclin binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031208"(POZ domain binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042802"(identical protein binding)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044346"(fibroblast apoptotic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071630"(nuclear protein quality control by the ubiquitin-proteasome system)|go:"GO:0072576"(liver morphogenesis)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901992"(positive regulation of mitotic cell cycle phase transition)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q9JLV5|rcsb pdb:1IUY|reactome:R-MMU-4641258|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-8932339|reactome:R-MMU-8951664|go:"GO:0030030"(cell projection organization)|reactome:R-MMU-9013418|reactome:R-MMU-9013422|reactome:R-MMU-9706019|reactome:R-MMU-983168|refseq:NP_057925.1|refseq:NP_001300657.1|hgnc:"MGI:1347360"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:tSFsLPpnn80evlnxKTXO5olW5Xg10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:O54991	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-774794|uniprotkb:A2A4K6|ensembl:ENSMUSP00000099398	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:cntp1_mouse(display_long)|uniprotkb:Neurexin-4(gene name synonym)|uniprotkb:Neurexin IV(gene name synonym)|uniprotkb:Paranodin(gene name synonym)|uniprotkb:NCP1(gene name synonym)|uniprotkb:MHDNIV(gene name synonym)|uniprotkb:Cntnap1(gene name)|psi-mi:Cntnap1(display_short)|uniprotkb:Nrxn4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_058062.2|ensembl:ENSMUSG00000017167(gene)|ensembl:ENSMUST00000103109(transcript)|go:"GO:0002175"(protein localization to paranode region of axon)|go:"GO:0005886"(plasma membrane)|go:"GO:0005918"(septate junction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019227"(neuronal action potential propagation)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030424"(axon)|go:"GO:0030913"(paranodal junction assembly)|go:"GO:0031175"(neuron projection development)|go:"GO:0033010"(paranodal junction)|go:"GO:0033270"(paranode region of axon)|go:"GO:0043209"(myelin sheath)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050884"(neuromuscular process controlling posture)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071205"(protein localization to juxtaparanode region of axon)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR028872|interpro:IPR036056|mint:O54991|hgnc:"MGI:1858201"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:BTW+FjgSUq00WpWGDC6PpQcIowE10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q5M8N0	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-16733235|ensembl:ENSMUSP00000050036|uniprotkb:Q3TAC7|uniprotkb:Q3UFR2	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:cnrp1_mouse(display_long)|uniprotkb:Cnrip1(gene name)|psi-mi:Cnrip1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000044629(gene)|ensembl:ENSMUST00000058159(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0031718"(type 1 cannabinoid receptor binding)|go:"GO:0043209"(myelin sheath)|go:"GO:2000272"(negative regulation of signaling receptor activity)|interpro:IPR029204|mint:Q5M8N0|refseq:NP_084137.1|hgnc:"MGI:1917505"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:d4VBaXMMjEQ11X2/zohvbiwN3k010090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q6ZQ38	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-597255|uniprotkb:Q6PFR0|uniprotkb:Q9CV45|ensembl:ENSMUSP00000020315	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:cand1_mouse(display_long)|uniprotkb:Cullin-associated and neddylation-dissociated protein 1(gene name synonym)|uniprotkb:p120 CAND1(gene name synonym)|uniprotkb:Cand1(gene name)|psi-mi:Cand1(display_short)|uniprotkb:D10Ertd516e(gene name synonym)|uniprotkb:Kiaa0829(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_082270.1|ensembl:ENSMUSG00000020114(gene)|ensembl:ENSMUST00000020315(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010265"(SCF complex assembly)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR013932("TATA-binding protein interacting (TIP20)")|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039852|mint:Q6ZQ38|reactome:R-MMU-6798695|reactome:R-MMU-8951664|reactome:R-MMU-917937|hgnc:"MGI:1261820"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:E6bJujLfT/V3C8Iyk0hUD1m4gT010090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:P28652	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-397029|uniprotkb:Q5SVH9|ensembl:ENSMUSP00000105438|ensembl:ENSMUSP00000105440	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:kcc2b_mouse(display_long)|uniprotkb:Camk2b(gene name)|psi-mi:Camk2b(display_short)|uniprotkb:Camk2d(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_031621.3|ensembl:ENSMUSG00000057897(gene)|ensembl:ENSMUST00000109813(transcript)|ensembl:ENSMUST00000109815(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030425"(dendrite)|go:"GO:0032222"(regulation of synaptic transmission, cholinergic)|go:"GO:0032430"(positive regulation of phospholipase A2 activity)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0002030"(inhibitory G protein-coupled receptor phosphorylation)|go:"GO:0043274"(phospholipase binding)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051233"(spindle midzone)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060466"(activation of meiosis involved in egg activation)|reactome:R-MMU-438066|reactome:R-MMU-5576892|reactome:R-MMU-5578775|reactome:R-MMU-5673000|reactome:R-MMU-5673001|reactome:R-MMU-877300|reactome:R-MMU-936837|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:2001222"(regulation of neuron migration)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|mint:P28652|reactome:R-MMU-3371571|reactome:R-MMU-399719|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|dip:DIP-31582N|hgnc:"MGI:88257"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:di/l1bhtPhzeKpErP6iyQfFypBo10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:P11798	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-400384|uniprotkb:Q61284|uniprotkb:Q6ZWN4|ensembl:ENSMUSP00000099952	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:kcc2a_mouse(display_long)|uniprotkb:Camk2a(gene name)|psi-mi:Camk2a(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_033922.1|refseq:NP_803126.1|refseq:NP_001273738.1|ensembl:ENSMUSG00000024617(gene)|ensembl:ENSMUST00000102888(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060996"(dendritic spine development)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099004"(calmodulin dependent kinase signaling pathway)|go:"GO:0099148"(regulation of synaptic vesicle docking)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099573"(glutamatergic postsynaptic density)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990443"(peptidyl-threonine autophosphorylation)|go:"GO:2000124"(regulation of endocannabinoid signaling pathway)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|mint:P11798|rcsb pdb:1HKX|rcsb pdb:4X3I|rcsb pdb:6TS3|reactome:R-MMU-3371571|reactome:R-MMU-399719|reactome:R-MMU-4086398|reactome:R-MMU-438066|reactome:R-MMU-5576892|reactome:R-MMU-5578775|reactome:R-MMU-5673000|reactome:R-MMU-5673001|reactome:R-MMU-877300|reactome:R-MMU-936837|dip:DIP-31593N|hgnc:"MGI:88256"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:mHdSlhGhe3sMOyO+YGwROtGOGfY10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:O88602	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-770326|ensembl:ENSMUSP00000019290	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:ccg2_mouse(display_long)|uniprotkb:Neuronal voltage-gated calcium channel gamma-2 subunit(gene name synonym)|uniprotkb:Stargazin(gene name synonym)|uniprotkb:Cacng2(gene name)|psi-mi:Cacng2(display_short)|uniprotkb:Stg(gene name synonym)|uniprotkb:Transmembrane AMPAR regulatory protein gamma-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_031609.1|dip:DIP-32457N|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0009986"(cell surface)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016247"(channel regulator activity)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0050877"(nervous system process)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051899"(membrane depolarization)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0060082"(eye blink reflex)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098943"(neurotransmitter receptor transport, postsynaptic endosome to lysosome)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099590"(neurotransmitter receptor internalization)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1904510"(positive regulation of protein localization to basolateral plasma membrane)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000969"(positive regulation of AMPA receptor activity)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR005422(Voltage-dependent calcium channel, gamma-2 subunit)|interpro:IPR008368(Voltage-dependent calcium channel, gamma subunit)|rcsb pdb:3JXT|rcsb pdb:4X3H|rcsb pdb:5KBS|rcsb pdb:5KBT|rcsb pdb:5KBU|rcsb pdb:5WEO|reactome:R-MMU-112308|reactome:R-MMU-399719|reactome:R-MMU-5682910|ensembl:ENSMUSG00000019146(gene)|ensembl:ENSMUST00000019290(transcript)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006612"(protein targeting to membrane)|hgnc:"MGI:1316660"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:horuxO013U9eKJYCTV7fS8OC0BY10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q8CC27	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-9690121|uniprotkb:A2ASJ8|uniprotkb:Q8C5J5|uniprotkb:Q9CTQ6|ensembl:ENSMUSP00000110371	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:cacb2_mouse(display_long)|uniprotkb:Cacnb2(gene name)|psi-mi:Cacnb2(display_short)|uniprotkb:Cacnlb2(gene name synonym)|uniprotkb:Calcium channel voltage-dependent subunit beta 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_001296448.1|refseq:NP_075605.1|refseq:XP_006497383.1|ensembl:ENSMUSG00000057914(gene)|ensembl:ENSMUST00000114723(transcript)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007601"(visual perception)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0070509"(calcium ion import)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0099635"(voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1901843"(positive regulation of high voltage-gated calcium channel activity)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|interpro:IPR001452(Src homology-3)|interpro:IPR005444(Voltage-dependent calcium channel, L-type, beta-2 subunit)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR035605|interpro:IPR036028|reactome:R-MMU-112308|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|hgnc:"MGI:894644"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:v56B+tEzuDuYnl4Fri/+kK+ccSo10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q8C726	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-16733202|ensembl:ENSMUSP00000078845|ensembl:ENSMUSP00000127300|ensembl:ENSMUSP00000157449	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:btbd9_mouse(display_long)|uniprotkb:Btbd9(gene name)|psi-mi:Btbd9(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000062202(gene)|ensembl:ENSMUST00000079924(transcript)|ensembl:ENSMUST00000168787(transcript)|ensembl:ENSMUST00000237048(transcript)|go:"GO:0007616"(long-term memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0042428"(serotonin metabolic process)|go:"GO:0042748"(circadian sleep/wake cycle, non-REM sleep)|go:"GO:0048512"(circadian behavior)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050951"(sensory perception of temperature stimulus)|go:"GO:0060586"(multicellular organismal iron ion homeostasis)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR008979(Galactose-binding like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR034091|refseq:NP_081336.1|refseq:NP_766206.1|hgnc:"MGI:1916625"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:7vki1FWZ5tJ1pPI3u/Mq54VkFis10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q68EF6	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-2310845|ensembl:ENSMUSP00000158999	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:begin_mouse(display_long)|uniprotkb:Begain(gene name)|psi-mi:Begain(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:XP_011242432.1|refseq:NP_001156647.1|refseq:XP_006516107.1|ensembl:ENSMUSG00000040867(gene)|ensembl:ENSMUST00000238841(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098817"(evoked excitatory postsynaptic potential)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR033584|interpro:IPR043441|hgnc:"MGI:3044626"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:F3zprvxGqUithFEHDTFZJDTWiOA10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q91XV3	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-772877|ensembl:ENSMUSP00000053943	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:basp1_mouse(display_long)|uniprotkb:Neuronal axonal membrane protein NAP-22(gene name synonym)|uniprotkb:22 kDa neuronal tissue-enriched acidic protein(gene name synonym)|uniprotkb:Basp1(gene name)|psi-mi:Basp1(display_short)|uniprotkb:Nap22(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_081671.1|ensembl:ENSMUSG00000045763(gene)|ensembl:ENSMUST00000058845(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0030426"(growth cone)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0072112"(glomerular visceral epithelial cell differentiation)|interpro:IPR008408(Brain acid soluble protein 1)|mint:Q91XV3|reactome:R-MMU-9035034|hgnc:"MGI:1917600"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:dwUwWfxMdUr+bki6HEHeaEibNOQ10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q8BKX1-3	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-16737310	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:q8bkx1-3(display_long)|uniprotkb:Baiap2(gene name)|psi-mi:Baiap2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	uniprotkb:Q8BKX1-3(isoform-parent)|hgnc:"MGI:2137336"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:ZjyE5WvbJoPRk33hovilo7Uqc4w10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:D3YX85	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-16737288|ensembl:ENSMUSP00000054631	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:d3yx85_mouse(display_long)|uniprotkb:Asap2(gene name)|psi-mi:Asap2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000052632(gene)|ensembl:ENSMUST00000050990(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0043547"(positive regulation of GTPase activity)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027267|interpro:IPR035677|interpro:IPR036028|interpro:IPR036770|interpro:IPR037278|interpro:IPR037844|interpro:IPR038508|interpro:IPR043593|go:"GO:0046872"(metal ion binding)|refseq:NP_001004364.2|hgnc:"MGI:2685438"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:GZyiDrokbrDoUTXeEEVLXpwlcjo10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:P59281-2	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-16735577|ensembl:ENSMUSP00000158984	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:p59281-2(display_long)|uniprotkb:Arhgap39(gene name)|psi-mi:Arhgap39(display_short)|uniprotkb:D15Wsu169e(gene name synonym)|uniprotkb:Kiaa1688(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	intact:EBI-772284(isoform-parent)|ensembl:ENSMUSG00000033697(gene)|ensembl:ENSMUST00000239134(transcript)|hgnc:"MGI:107858"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:xxFSkacr9YHzYICJc/WOPs3s7Zk10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:P61205	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-444797|uniprotkb:P16587|ensembl:ENSMUSP00000050689	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:arf3_mouse(display_long)|uniprotkb:Arf3(gene name)|psi-mi:Arf3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_031504.1|refseq:XP_011243747.1|ensembl:ENSMUSG00000051853(gene)|ensembl:ENSMUST00000053183(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P61205|reactome:R-MMU-1660514|reactome:R-MMU-6807878|reactome:R-MMU-6811434|hgnc:"MGI:99432"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:np09WjdbXRu9vgMbiXn9EA3ExqA10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q9WV31	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-397779|ensembl:ENSMUSP00000023268|ensembl:ENSMUSP00000105636|uniprotkb:Q9ES15	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:arc_mouse(display_long)|uniprotkb:Arc(gene name)|psi-mi:Arc(display_short)|uniprotkb:Activity-regulated gene 3.1 protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_001263613.1|ensembl:ENSMUSG00000022602(gene)|ensembl:ENSMUST00000023268(transcript)|ensembl:ENSMUST00000110009(transcript)|refseq:NP_061260.1|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0003729"(mRNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007492"(endoderm development)|go:"GO:0007612"(learning)|go:"GO:0007616"(long-term memory)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030425"(dendrite)|go:"GO:0031901"(early endosome membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0045121"(membrane raft)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051028"(mRNA transport)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098845"(postsynaptic endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:0110077"(vesicle-mediated intercellular transport)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900452"(regulation of long-term synaptic depression)|go:"GO:1903561"(extracellular vesicle)|go:"GO:2000969"(positive regulation of AMPA receptor activity)|interpro:IPR023263|interpro:IPR040814|dip:DIP-31565N|hgnc:"MGI:88067"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:vZutgYl26hWTDm9UgMeY8dtgbg810090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q8BIZ1	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-16724439|uniprotkb:E9Q644|uniprotkb:Q4KMR9|uniprotkb:Q8BJ47|uniprotkb:Q8BJ49	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:ans1b_mouse(display_long)|uniprotkb:Amyloid-beta protein intracellular domain-associated protein 1(gene name synonym)|uniprotkb:E2A-PBX1-associated protein(gene name synonym)|uniprotkb:Anks1b(gene name)|psi-mi:Anks1b(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	interpro:IPR041880|interpro:IPR041882|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1900383"(regulation of synaptic plasticity by receptor localization to synapse)|mint:Q8BIZ1|refseq:NP_001170868.1|refseq:NP_001170869.1|refseq:NP_001333982.1|refseq:NP_001333983.1|refseq:NP_852063.1|interpro:IPR033636|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|hgnc:"MGI:1924781"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:xm2OG9kb/tmIo7e7c/qXBE4JeAY10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q8C8R3-2	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-16737278	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:q8c8r3-2(display_long)|uniprotkb:Ank2(gene name)|psi-mi:Ank2(display_short)|uniprotkb:AnkB(gene name synonym)|uniprotkb:Ankyrin-B(gene name synonym)|uniprotkb:Brain ankyrin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	intact:EBI-774322(isoform-parent)|hgnc:"MGI:88025"(identity)	go:"GO:0014069"(postsynaptic density)	-	isoform-comment:Incomplete sequence. Contains a phosphoserine at position 30.	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:3toVISZ60jqOBOF74OugVTzYOtc10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q7TQF7	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-775139|uniprotkb:Q8R1C4|ensembl:ENSMUSP00000003345	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:amph_mouse(display_long)|uniprotkb:Amph(gene name)|psi-mi:Amph(display_short)|uniprotkb:Amph1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_001276475.1|refseq:NP_778172.1|go:"GO:0005886"(plasma membrane)|go:"GO:0007612"(learning)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031256"(leading edge membrane)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098833"(presynaptic endocytic zone)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003017(Amphiphysin, isoform 1)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035470|interpro:IPR036028|mint:Q7TQF7|reactome:R-MMU-8856828|go:"GO:0005856"(cytoskeleton)|ensembl:ENSMUSG00000021314(gene)|ensembl:ENSMUST00000003345(transcript)|go:"GO:0005543"(phospholipid binding)|hgnc:"MGI:103574"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:EK7yC2pu1BmtW4xYQSU9lUAmCJk10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q3UHD9	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)|hgnc:"MGI:3580016"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:E9Q3K3	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-16737254|ensembl:ENSMUSP00000074478	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:e9q3k3_mouse(display_long)|uniprotkb:Agap1(gene name)|psi-mi:Agap1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000055013(gene)|ensembl:ENSMUST00000074945(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|hgnc:"MGI:2653690"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:Xij8bDL/krWFV/jPi70PzBIaHBs10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q3UYH7	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-6903286|ensembl:ENSMUSP00000070445|uniprotkb:F8VPM8	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:arbk2_mouse(display_long)|uniprotkb:Adrbk2(gene name)|psi-mi:Adrbk2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_001272735.1|ensembl:ENSMUSG00000042249(gene)|ensembl:ENSMUST00000065167(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002029"(desensitization of G protein-coupled receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004703"(G protein-coupled receptor kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0031623"(receptor internalization)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0044292"(dendrite terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0046154"(rhodopsin metabolic process)|go:"GO:0047696"(beta-adrenergic receptor kinase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0097225"(sperm midpiece)|interpro:IPR000239(GPCR kinase)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036305|reactome:R-MMU-418555|reactome:R-MMU-8856825|interpro:IPR011009(Protein kinase-like)|refseq:NP_796052.2|hgnc:"MGI:87941"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:m47GkeIFhWFm0T6NfQfcZcIvqUM10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q61072	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-77983|uniprotkb:E9QPP2|ensembl:ENSMUSP00000081048|uniprotkb:Q60618|uniprotkb:Q61853|uniprotkb:Q80U94	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:adam9_mouse(display_long)|uniprotkb:Adam9(gene name)|psi-mi:Adam9(display_short)|uniprotkb:Kiaa0021(gene name synonym)|uniprotkb:Mdc9(gene name synonym)|uniprotkb:Mltng(gene name synonym)|uniprotkb:Metalloprotease/disintegrin/cysteine-rich protein 9(gene name synonym)|uniprotkb:Myeloma cell metalloproteinase(gene name synonym)|uniprotkb:Meltrin-gamma(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	ensembl:ENSMUSG00000031555(gene)|ensembl:ENSMUST00000084035(transcript)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0009986"(cell surface)|go:"GO:0010042"(response to manganese ion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016485"(protein processing)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031233"(intrinsic component of external side of plasma membrane)|go:"GO:0031293"(membrane protein intracellular domain proteolysis)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033630"(positive regulation of cell adhesion mediated by integrin)|go:"GO:0033631"(cell-cell adhesion mediated by integrin)|go:"GO:0034241"(positive regulation of macrophage fusion)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0042117"(monocyte activation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042987"(amyloid precursor protein catabolic process)|go:"GO:0043236"(laminin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902945"(metalloendopeptidase activity involved in amyloid precursor protein catabolic process)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR018358|interpro:IPR024079|interpro:IPR034027|interpro:IPR036436|refseq:NP_031430.2|hgnc:"MGI:105376"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:GSTKev8sg5lfwupVNEpPkPhFxHA10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q9R1V6	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-770007|uniprotkb:Q5TLI8|uniprotkb:Q5TLI9|uniprotkb:Q5TLJ0|uniprotkb:Q5TLJ1|uniprotkb:Q5TLJ2|uniprotkb:Q5TLJ3|uniprotkb:Q5TLJ4|uniprotkb:Q5TLJ5|uniprotkb:Q5TLJ6|uniprotkb:Q5TLJ7|uniprotkb:Q5TLJ8|uniprotkb:Q5TLJ9|uniprotkb:Q5TLK0|uniprotkb:Q5TLK1|uniprotkb:Q5TLK2|uniprotkb:Q5TLK3|uniprotkb:Q5TLK4|uniprotkb:Q5TLK5|uniprotkb:Q5TLK6|uniprotkb:Q5TLK7|uniprotkb:Q5TLK8|uniprotkb:Q8BSF2|uniprotkb:Q9R1V5|ensembl:ENSMUSP00000086139	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:ada22_mouse(display_long)|uniprotkb:Adam22(gene name)|psi-mi:Adam22(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_001007221.1|refseq:NP_001007222.1|refseq:NP_001091695.1|refseq:NP_001297368.1|refseq:NP_001297369.1|refseq:XP_006503592.1|refseq:XP_006503593.1|refseq:XP_006503594.1|refseq:XP_006503596.1|refseq:XP_006503598.1|refseq:XP_006503600.1|refseq:XP_006503605.1|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR006586(ADAM, cysteine-rich)|interpro:IPR013111(EGF, extracellular)|interpro:IPR018358|interpro:IPR024079|interpro:IPR034027|interpro:IPR036436|mint:Q9R1V6|reactome:R-MMU-5682910|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|ensembl:ENSMUSG00000040537(gene)|ensembl:ENSMUST00000088761(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014037"(Schwann cell differentiation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030424"(axon)|go:"GO:0042063"(gliogenesis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|hgnc:"MGI:1340046"(identity)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:jOd0AHmc5bv3EK95Q84gaYLiKx010090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q8K4G5-4	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-16737246|ensembl:ENSMUSP00000096897	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:q8k4g5-4(display_long)|uniprotkb:Actin-binding LIM protein family member 1(gene name synonym)|uniprotkb:Ablim1(gene name)|psi-mi:Ablim1(display_short)|uniprotkb:Ablim(gene name synonym)|uniprotkb:Kiaa0059(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16737600|imex:IM-26370-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	intact:EBI-2307994(isoform-parent)|ensembl:ENSMUSG00000025085(gene)|ensembl:ENSMUST00000099294(transcript)|hgnc:"MGI:1194500"(identity)	go:"GO:0014069"(postsynaptic density)	-	isoform-comment:No experimental confirmation available.	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/01/08	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:keGLqhZ2HAGsZw242CnpRmkTc9E10090	rigid:R5raVh7syIW+IuXOGBxnuBFTBu8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:F6SEU4	uniprotkb:Q01097	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-400125|uniprotkb:Q9DCB2	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:nmde2_mouse(display_long)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-2(gene name synonym)|uniprotkb:Grin2b(gene name)|psi-mi:Grin2b(display_short)|uniprotkb:N-methyl D-aspartate receptor subtype 2B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16738138|imex:IM-26370-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_032197.3|go:"GO:0001508"(action potential)|go:"GO:0001662"(behavioral fear response)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001964"(startle response)|go:"GO:0001967"(suckling behavior)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005234"(extracellularly glutamate-gated ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007423"(sensory organ development)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008306"(associative learning)|go:"GO:0009986"(cell surface)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016594"(glycine binding)|go:"GO:0016595"(glutamate binding)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0030018"(Z disc)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0036094"(small molecule binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0042596"(fear response)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043113"(receptor clustering)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0044307"(dendritic branch)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0046960"(sensitization)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0048511"(rhythmic process)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099529"(neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential)|go:"GO:0099583"(neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|go:"GO:0099566"(regulation of postsynaptic cytosolic calcium ion concentration)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018884|interpro:IPR019594|interpro:IPR028082|reactome:R-MMU-3928662|reactome:R-MMU-438066|reactome:R-MMU-5673001|reactome:R-MMU-8849932|reactome:R-MMU-9609736|mint:Q01097|dip:DIP-31568N	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Fig. 2|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/01/16	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:SvjoNuuHCFT+Yj1woYrEvU6n8B010090	rigid:HEvGgDSkwj3xnoMOu80Ae9yUabw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:F6SEU4	uniprotkb:Q3UHD9	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16738138|imex:IM-26370-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Fig. 2|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/01/16	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rigid:HEvGgDSkwj3xnoMOu80Ae9yUabw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:F6SEU4	uniprotkb:Q9WV60	intact:EBI-5797569|ensembl:ENSMUSP00000141686	intact:EBI-400793|ensembl:ENSMUSP00000023507	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:gsk3b_mouse(display_long)|uniprotkb:Gsk3b(gene name)|psi-mi:Gsk3b(display_short)|uniprotkb:Serine/threonine-protein kinase GSK3B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16738138|imex:IM-26370-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	refseq:NP_062801.1|dip:DIP-32446N|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006983"(ER overload response)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0007520"(myoblast fusion)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010822"(positive regulation of mitochondrion organization)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014043"(negative regulation of neuron maturation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0034452"(dynactin binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|go:"GO:2000738"(positive regulation of stem cell differentiation)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033573|interpro:IPR039192|mint:Q9WV60|rcsb pdb:4NU1|rcsb pdb:5AIR|rcsb pdb:6AE3|reactome:R-MMU-195253|reactome:R-MMU-196299|reactome:R-MMU-3371453|reactome:R-MMU-399956|reactome:R-MMU-4641262|reactome:R-MMU-5250924|reactome:R-MMU-5610785|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035733"(hepatic stellate cell activation)|go:"GO:0036016"(cellular response to interleukin-3)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043227"(membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044027"(hypermethylation of CpG island)|go:"GO:0044297"(cell body)|go:"GO:0045121"(membrane raft)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046849"(bone remodeling)|go:"GO:0048156"(tau protein binding)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071109"(superior temporal gyrus development)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090290"(positive regulation of osteoclast proliferation)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099159"(regulation of modification of postsynaptic structure)|go:"GO:0106027"(neuron projection organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0150101"(regulation of microtubule anchoring at centrosome)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1901030"(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901984"(negative regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1904339"(negative regulation of dopaminergic neuron differentiation)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904780"(negative regulation of protein localization to centrosome)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000171"(negative regulation of dendrite development)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|ensembl:ENSMUSG00000022812(gene)|ensembl:ENSMUST00000023507(transcript)|go:"GO:0000320"(re-entry into mitotic cell cycle)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Fig. 2|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/01/16	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rogid:FKe0WkOBBYU0vIJLmcFNMJ+KVHA10090	rigid:HEvGgDSkwj3xnoMOu80Ae9yUabw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q3UHD9	uniprotkb:Q5F258	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16735713|ensembl:ENSMUSP00000098375	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:q5f258_mouse(display_long)|uniprotkb:Git1(gene name)|psi-mi:Git1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16738106|imex:IM-26370-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000011877(gene)|ensembl:ENSMUST00000100812(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR002110(Ankyrin)|interpro:IPR013724("Spa2 homology (SHD) of GIT")|interpro:IPR020683|interpro:IPR022018|interpro:IPR032352|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|refseq:XP_006533012.1	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Fig. 2|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/01/16	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:w9oRo1556FC2b4vWr5xT7wnG+wI10090	rigid:mdhZ69WjhfcFdU21WYxpUOtVxpM	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q3UHD9	uniprotkb:A2CG49	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16738106|imex:IM-26370-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Fig. 2|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/01/16	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rigid:mdhZ69WjhfcFdU21WYxpUOtVxpM	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q3UHD9	uniprotkb:Q62108	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-300895|ensembl:ENSMUSP00000104229|uniprotkb:Q5NCV5|uniprotkb:Q5NCV6|uniprotkb:Q5NCV7|uniprotkb:Q91WJ1	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:dlg4_mouse(display_long)|uniprotkb:Dlg4(gene name)|psi-mi:Dlg4(display_short)|uniprotkb:Dlgh4(gene name synonym)|uniprotkb:Psd95(gene name synonym)|uniprotkb:Postsynaptic density protein 95(gene name synonym)|uniprotkb:Synapse-associated protein 90(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16738106|imex:IM-26370-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000020886(gene)|ensembl:ENSMUST00000108588(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0019894"(kinesin binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031812"(P2Y1 nucleotide receptor binding)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0035176"(social behavior)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071625"(vocalization behavior)|go:"GO:0071944"(cell periphery)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097109"(neuroligin family protein binding)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|go:"GO:0060076"(excitatory synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|mint:Q62108|reactome:R-MMU-399719|reactome:R-MMU-438066|reactome:R-MMU-451308|reactome:R-MMU-5625900|reactome:R-MMU-5673001|reactome:R-MMU-5682910|reactome:R-MMU-6794361|reactome:R-MMU-8849932|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|refseq:NP_001103222.1|refseq:NP_031890.1|dip:DIP-29888N	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Fig. 2|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/01/16	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:9Ylvs2goE8Z/6ff4AqFCEKrPanY10090	rigid:mdhZ69WjhfcFdU21WYxpUOtVxpM	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:A2CG49	uniprotkb:P49025	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-397301|intact:EBI-487846|uniprotkb:O88528|uniprotkb:O88937|uniprotkb:O88938|uniprotkb:Q3UM99|uniprotkb:Q8CIJ1	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:ctro_mouse(display_long)|uniprotkb:Cit(gene name)|psi-mi:Cit(display_short)|uniprotkb:Rho-interacting, serine/threonine-protein kinase 21(gene name synonym)|uniprotkb:Crik(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16738122|imex:IM-26370-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001180(Citron-like)|interpro:IPR017405(Citron Rho-interacting kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|refseq:XP_006530214.1|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001726"(ruffle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|interpro:IPR037708|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030496"(midbody)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0005856"(cytoskeleton)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048699"(generation of neurons)|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013149|reactome:R-MMU-5625900	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Fig. 2|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/01/16	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:8kykadVIiyk12GjGCZNn0bQ13C010090	rigid:+njULYnwzaRGNMZrEjD1pmOFi4k	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:A2CG49	uniprotkb:P11798	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-400384|uniprotkb:Q61284|uniprotkb:Q6ZWN4|ensembl:ENSMUSP00000099952	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:kcc2a_mouse(display_long)|uniprotkb:Camk2a(gene name)|psi-mi:Camk2a(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16738122|imex:IM-26370-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	refseq:NP_033922.1|refseq:NP_803126.1|refseq:NP_001273738.1|ensembl:ENSMUSG00000024617(gene)|ensembl:ENSMUST00000102888(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060996"(dendritic spine development)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099004"(calmodulin dependent kinase signaling pathway)|go:"GO:0099148"(regulation of synaptic vesicle docking)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099573"(glutamatergic postsynaptic density)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990443"(peptidyl-threonine autophosphorylation)|go:"GO:2000124"(regulation of endocannabinoid signaling pathway)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|mint:P11798|rcsb pdb:1HKX|rcsb pdb:4X3I|rcsb pdb:6TS3|reactome:R-MMU-3371571|reactome:R-MMU-399719|reactome:R-MMU-4086398|reactome:R-MMU-438066|reactome:R-MMU-5576892|reactome:R-MMU-5578775|reactome:R-MMU-5673000|reactome:R-MMU-5673001|reactome:R-MMU-877300|reactome:R-MMU-936837|dip:DIP-31593N	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Fig. 2|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/01/16	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:mHdSlhGhe3sMOyO+YGwROtGOGfY10090	rigid:+njULYnwzaRGNMZrEjD1pmOFi4k	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:A2CG49	uniprotkb:F6SEU4	intact:EBI-770321|uniprotkb:A2CG50|uniprotkb:A2CG51|uniprotkb:A2CG52|uniprotkb:A2CG53|uniprotkb:Q3TYL1|uniprotkb:Q3UTA5|uniprotkb:Q8BTT9|uniprotkb:Q8C4Q2|uniprotkb:Q9CVA9|uniprotkb:Q3TXY8|uniprotkb:B2RXR5|uniprotkb:D3Z559|ensembl:ENSMUSP00000076088	intact:EBI-5797569|ensembl:ENSMUSP00000141686	psi-mi:kalrn_mouse(display_long)|uniprotkb:Protein Duo(gene name synonym)|uniprotkb:Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain(gene name synonym)|uniprotkb:Kalrn(gene name)|psi-mi:Kalrn(display_short)	psi-mi:sygp1_mouse(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16738122|imex:IM-26370-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001157740.1|refseq:XP_006522445.1|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR018159|interpro:IPR028570|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSMUSG00000061751(gene)|ensembl:ENSMUST00000076810(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007417"(central nervous system development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0035176"(social behavior)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042711"(maternal behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046959"(habituation)|mint:A2CG49|rcsb pdb:1WFW|reactome:R-MMU-193648|reactome:R-MMU-3928662|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-5687128|reactome:R-MMU-8980692|reactome:R-MMU-9013149|reactome:R-MMU-9013408|interpro:IPR036865	refseq:NP_001268420.1|ensembl:ENSMUSG00000067629(gene)|ensembl:ENSMUST00000194598(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:F6SEU4|rcsb pdb:5JXC|reactome:R-MMU-5658442	go:"GO:0014069"(postsynaptic density)	-	-	figure legend:Fig. 2|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/01/16	rogid:pDqdA2QNbqgLE3eYQXVVW2cxIyo10090	rogid:X1QOpwn0EU5av7G5/QRYmQopTdM10090	rigid:+njULYnwzaRGNMZrEjD1pmOFi4k	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q3UHD9	uniprotkb:O88485	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-492834|uniprotkb:O88486|uniprotkb:Q80W09|ensembl:ENSMUSP00000111221	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:dc1i1_mouse(display_long)|uniprotkb:Cytoplasmic dynein intermediate chain 1(gene name synonym)|uniprotkb:Dynein intermediate chain 1, cytosolic(gene name synonym)|uniprotkb:Dync1i1(gene name)|psi-mi:Dync1i1(display_short)|uniprotkb:Dncic1(gene name synonym)|uniprotkb:Dnci1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001177952.1|refseq:NP_001177954.1|refseq:NP_034193.2|ensembl:ENSMUSG00000029757(gene)|ensembl:ENSMUST00000115559(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0010970"(transport along microtubule)|go:"GO:0030507"(spectrin binding)|go:"GO:0031982"(vesicle)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045503"(dynein light chain binding)|go:"GO:0045504"(dynein heavy chain binding)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR025956|interpro:IPR036322|mint:O88485|reactome:R-MMU-141444|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-9646399|reactome:R-MMU-9648025|dip:DIP-32048N|hgnc:"MGI:107743"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:dX76CwZf2s90Mf2WmBgQqNGcgi410090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q80TL0	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-8312547|ensembl:ENSMUSP00000061278|uniprotkb:Q8CB81|uniprotkb:Q5SX30|intact:MINT-4114921|uniprotkb:Q8BGM6	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:ppm1e_mouse(display_long)|uniprotkb:Ppm1e(gene name)|psi-mi:Ppm1e(display_short)|uniprotkb:"Ca(2+)/calmodulin-dependent protein kinase phosphatase N"(gene name synonym)|uniprotkb:CaMKP-nucleus(gene name synonym)|uniprotkb:Partner of PIX 1(gene name synonym)|uniprotkb:Partner of PIX-alpha(gene name synonym)|uniprotkb:Camkn(gene name synonym)|uniprotkb:Kiaa1072(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	go:"GO:0035690"|ensembl:ENSMUSG00000046442(gene)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0106306"|go:"GO:0106307"|ensembl:ENSMUST00000055438(transcript)|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:Q80TL0|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0032991"(protein-containing complex)|refseq:NP_796141.2|hgnc:"MGI:2444096"(identity)	-	-	comment:mint|function:Protein phosphatase that inactivates multifunctional CaM kinases such as CAMK4 and CAMK2. Dephosphorylates and inactivates PAK. May play a role in the inhibition of actin fiber stress breakdown and in morphological changes driven by TNK2/CDC42	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:8/FKsvuq3Sv4ibrqnNC0UR3ypiI10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q8R1Q8	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-8314868|ensembl:ENSMUSP00000035366|intact:MINT-4118631	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:dc1l1_mouse(display_long)|uniprotkb:Dync1li1(gene name)|psi-mi:Dync1li1(display_short)|uniprotkb:Dncli1(gene name synonym)|uniprotkb:Dnclic1(gene name synonym)|uniprotkb:Dynein light intermediate chain 1, cytosolic(gene name synonym)|uniprotkb:Dynein light chain A(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000032435(gene)|ensembl:ENSMUST00000047404(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007049"(cell cycle)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045504"(dynein heavy chain binding)|go:"GO:0046605"(regulation of centrosome cycle)|go:"GO:0051301"(cell division)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR008467(Dynein light intermediate chain)|interpro:IPR022780|interpro:IPR027417|mint:Q8R1Q8|reactome:R-MMU-141444|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-5663220|reactome:R-MMU-6798695|reactome:R-MMU-6807878|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-9646399|reactome:R-MMU-9648025|refseq:NP_666341.1|hgnc:"MGI:2135610"(identity)	-	-	function:May play a role in binding dynein to membranous organelles or chromosomes. May associate with the heavy chains in the dynein head where they might regulate enzyme activity|comment:mint	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:aAQ4kBil3eYqmqS/J6QhMDA6a4410090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P83510	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-7280013|intact:MINT-4138101|ensembl:ENSMUSP00000124681	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:tnik_mouse(display_long)|uniprotkb:Tnik(gene name)|psi-mi:Tnik(display_short)|uniprotkb:Kiaa0551(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001156480.1|ensembl:ENSMUSG00000027692(gene)|ensembl:ENSMUST00000159236(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007256"(obsolete activation of JNKK activity)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001180(Citron-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P83510|reactome:R-MMU-2559580|go:"GO:0055037"(recycling endosome)|dip:DIP-57467N|hgnc:"MGI:1916264"(identity)	-	-	comment:mint|function:Stress-activated serine/threonine kinase that may play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. May play a role in cytoskeletal regulation	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:+Hdc1nFS32RS9/n1kdeF66gw2zs10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:O35954	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-8327777|intact:MINT-4104925|ensembl:ENSMUSP00000054309|ensembl:ENSMUSP00000097599	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:pitm1_mouse(display_long)|uniprotkb:Pitpnm1(gene name)|psi-mi:Pitpnm1(display_short)|uniprotkb:Dres9(gene name synonym)|uniprotkb:Mpt1(gene name synonym)|uniprotkb:Nir2(gene name synonym)|uniprotkb:Pitpnm(gene name synonym)|uniprotkb:Phosphatidylinositol transfer protein, membrane-associated 1(gene name synonym)|uniprotkb:Mpt-1(gene name synonym)|uniprotkb:Pyk2 N-terminal domain-interacting receptor 2(gene name synonym)|uniprotkb:Drosophila retinal degeneration B homolog 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_032877.1|ensembl:ENSMUSG00000024851(gene)|ensembl:ENSMUST00000049658(transcript)|ensembl:ENSMUST00000100022(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0008525"(phosphatidylcholine transporter activity)|go:"GO:0008526"(phosphatidylinositol transfer activity)|go:"GO:0015031"(protein transport)|go:"GO:0015914"(phospholipid transport)|go:"GO:0030496"(midbody)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044297"(cell body)|go:"GO:0070300"(phosphatidic acid binding)|interpro:IPR001666(Phosphatidylinositol transfer protein)|interpro:IPR004177(DDHD)|interpro:IPR023214|interpro:IPR023393|interpro:IPR031315|interpro:IPR036412|mint:O35954|reactome:R-MMU-1483226|hgnc:"MGI:1197524"(identity)	-	-	comment:mint|function:"Regulates RHOA activity, and plays a role in cytoskeleton remodeling. Necessary for normal completion of cytokinesis. Plays a role in maintaining normal diacylglycerol levels in the Golgi apparatus. Binds phosphatidyl inositol phosphates (in vitro). May catalyze the transfer of phosphatidylinositol and phosphatidylcholine between membranes (By similarity). Necessary for maintaining the normal structure of the endoplasmic reticulum and the Golgi apparatus. Required for protein export from the endoplasmic reticulum and the Golgi. Binds calcium ions"	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:FOv7BJbaEF2IBuGzhURvp2lPVRs10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q8R4U7	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-7991189|uniprotkb:Q8BQW1|uniprotkb:Q7TS71|uniprotkb:Q9CSL6|uniprotkb:Q99NG3|intact:MINT-4119192|uniprotkb:A3KG96|uniprotkb:Q3UV18|ensembl:ENSMUSP00000001116|ensembl:ENSMUSP00000060619|ensembl:ENSMUSP00000101475|ensembl:ENSMUSP00000130758	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:luzp1_mouse(display_long)|uniprotkb:Luzp1(gene name)|psi-mi:Luzp1(display_short)|uniprotkb:Luzp(gene name synonym)|uniprotkb:Leucine zipper motif-containing protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_077772.2|refseq:XP_006538984.1|ensembl:ENSMUSG00000001089(gene)|ensembl:ENSMUST00000001116(transcript)|ensembl:ENSMUST00000063021(transcript)|ensembl:ENSMUST00000105849(transcript)|ensembl:ENSMUST00000170102(transcript)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0021503"(neural fold bending)|go:"GO:0060840"(artery development)|interpro:IPR026734|mint:Q8R4U7|hgnc:"MGI:107629"(identity)	-	-	comment:mint	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:iDQj2aaSiq5/yW5J1vZ3YnF8ru410090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:B2RQG2	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16750807|ensembl:ENSMUSP00000085650|ensembl:ENSMUSP00000139610	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:b2rqg2_mouse(display_long)|uniprotkb:Phf3(gene name)|psi-mi:Phf3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000048874(gene)|ensembl:ENSMUST00000088310(transcript)|ensembl:ENSMUST00000186733(transcript)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003618(Transcription elongation factor S-II, central region)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012921(Spen paralogue and orthologue C-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036575|refseq:NP_001074549.1|refseq:XP_006495899.1|refseq:XP_006495900.1|hgnc:"MGI:2446126"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:gNGM+2LQ8Abj/yeaztgAO/Jp1Dk10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:E9PW37	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16725503|ensembl:ENSMUSP00000077423	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:e9pw37_mouse(display_long)|uniprotkb:Rasal2(gene name)|psi-mi:Rasal2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000070565(gene)|ensembl:ENSMUST00000078308(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007165"(signal transduction)|go:"GO:0043087"(regulation of GTPase activity)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR039360|reactome:R-MMU-5658442|reactome:R-MMU-9696264|reactome:R-MMU-9696273|refseq:NP_808312.3|hgnc:"MGI:2443881"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:ZIal1IuCekt9MxN5+SgsQJnrcsM10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:H3BKQ3	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16750787|ensembl:ENSMUSP00000135479	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:h3bkq3_mouse(display_long)|uniprotkb:Evi5l(gene name)|psi-mi:Evi5l(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000011832(gene)|ensembl:ENSMUST00000176149(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1902018"(negative regulation of cilium assembly)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR031214|interpro:IPR035969|refseq:NP_001333659.1|hgnc:"MGI:2442167"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:k19Yl8SzBPtgZKAIgm25vx5tAmM10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:B8QI33	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16750773	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:b8qi33_mouse(display_long)|uniprotkb:Ppfia1(gene name)|psi-mi:Ppfia1(display_short)|uniprotkb:ppfia1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0032991"(protein-containing complex)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR037620|interpro:IPR037621|interpro:IPR037622|interpro:IPR029515|interpro:IPR030438|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|hgnc:"MGI:1924750"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:tOGOF5fFFo77IFifmUNrEChsm3o10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:A0A0A6YY83	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16750754|ensembl:ENSMUSP00000142319	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:a0a0a6yy83_mouse(display_long)|uniprotkb:Pcdh7(gene name)|psi-mi:Pcdh7(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000029108(gene)|ensembl:ENSMUST00000191837(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|interpro:IPR002126(Cadherin)|interpro:IPR013164(Cadherin, N-terminal)|interpro:IPR013585(Protocadherin)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|reactome:R-MMU-114608|reactome:R-MMU-8980692|reactome:R-MMU-9013026|refseq:NP_001116230.1|hgnc:"MGI:1860487"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:3aGRoHk1wOOVj0VjnnLinAMOwPw10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q9Z2Q6	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-772125|uniprotkb:Q3UYG4|uniprotkb:Q6PB74|uniprotkb:B2RUC5|ensembl:ENSMUSP00000094750	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:sept5_mouse(display_long)|uniprotkb:Septin5(gene name)|psi-mi:Septin5(display_short)|uniprotkb:Cell division control-related protein 1(gene name synonym)|uniprotkb:Peanut-like protein 1(gene name synonym)|uniprotkb:Pnutl1(gene name synonym)|uniprotkb:Sept5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_998779.2|ensembl:ENSMUSG00000072214(gene)|ensembl:ENSMUST00000096987(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0005940"(septin ring)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019003"(GDP binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030534"(adult behavior)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035176"(social behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043679"(axon terminus)|go:"GO:0044305"(calyx of Held)|go:"GO:0045202"(synapse)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0098793"(presynapse)|go:"GO:0099148"(regulation of synaptic vesicle docking)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030647|mint:Q9Z2Q6|hgnc:"MGI:1195461"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:9ZY1BrCZ/7+83bn/q3OQkZoi8pg10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:E9Q616	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-12601627|ensembl:ENSMUSP00000090633	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:e9q616_mouse(display_long)|uniprotkb:Ahnak(gene name)|psi-mi:Ahnak(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000069833(gene)|ensembl:ENSMUST00000092956(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0031982"(vesicle)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|refseq:NP_033773.1|refseq:XP_006527316.1|hgnc:"MGI:1316648"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:W4kwtfEjyBD8hEog1jI9SKpeYO010090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q68FG2	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-2255511|ensembl:ENSMUSP00000008991	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:q68fg2_mouse(display_long)|uniprotkb:Sptbn2(gene name)|psi-mi:Sptbn2(display_short)|uniprotkb:Spnb3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_067262.1|refseq:XP_006531767.1|refseq:XP_006531768.1|ensembl:ENSMUSG00000067889(gene)|ensembl:ENSMUST00000008991(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007416"(synapse assembly)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008091"(spectrin)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0021692"(cerebellar Purkinje cell layer morphogenesis)|go:"GO:0030534"(adult behavior)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051693"(actin filament capping)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098918"(structural constituent of synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|go:"GO:0099189"(postsynaptic spectrin-associated cytoskeleton)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|interpro:IPR041681|reactome:R-MMU-2132295|reactome:R-MMU-375165|reactome:R-MMU-445095|reactome:R-MMU-5673001|reactome:R-MMU-6807878|hgnc:"MGI:1313261"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:2F7U0dl21KxXpc9Z2sk7D/wzQvM10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:E0CXD4	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-11123891|ensembl:ENSMUSP00000124732	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:e0cxd4_mouse(display_long)|uniprotkb:Pcdh1(gene name)|psi-mi:Pcdh1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000051375(gene)|ensembl:ENSMUST00000160721(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0030054"(cell junction)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002126(Cadherin)|interpro:IPR013164(Cadherin, N-terminal)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|hgnc:"MGI:104692"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:jbq08U76h//x6Kw9EEyR69I5TX810090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q8BYI9	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-774167|uniprotkb:A2RT70|uniprotkb:O88717|ensembl:ENSMUSP00000107298|ensembl:ENSMUSP00000141553	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:tenr_mouse(display_long)|uniprotkb:Restrictin(gene name synonym)|uniprotkb:Janusin(gene name synonym)|uniprotkb:Neural recognition molecule J1-160/180(gene name synonym)|uniprotkb:Tnr(gene name)|psi-mi:Tnr(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_071707.2|refseq:XP_006496805.1|refseq:XP_006496806.1|refseq:XP_006496807.1|ensembl:ENSMUSG00000015829(gene)|ensembl:ENSMUST00000111669(transcript)|ensembl:ENSMUST00000192069(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007155"(cell adhesion)|go:"GO:0007158"(neuron cell-cell adhesion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0008306"(associative learning)|go:"GO:0009986"(cell surface)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0045121"(membrane raft)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0048692"(negative regulation of axon extension involved in regeneration)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0050808"(synapse organization)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072534"(perineuronal net)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098966"(perisynaptic extracellular matrix)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR033079|interpro:IPR036056|interpro:IPR036116|interpro:IPR041161|mint:Q8BYI9|reactome:R-MMU-3000178|hgnc:"MGI:99516"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:K7s7yPGS4RvIe+thCkAZIFGjNRA10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q62261	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-397843|ensembl:ENSMUSP00000006629|ensembl:ENSMUSP00000011877|uniprotkb:A2AFU1|uniprotkb:Q3TEM7|uniprotkb:Q5SQL8|uniprotkb:Q5SQL9|uniprotkb:Q9QWJ7	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:sptb2_mouse(display_long)|uniprotkb:Sptbn1(gene name)|psi-mi:Sptbn1(display_short)|uniprotkb:Spnb-2(gene name synonym)|uniprotkb:Spnb2(gene name synonym)|uniprotkb:Sptb2(gene name synonym)|uniprotkb:Beta-II spectrin(gene name synonym)|uniprotkb:Fodrin beta chain(gene name synonym)|uniprotkb:Embryonic liver fodrin(gene name synonym)|uniprotkb:Elf(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000020315(gene)|ensembl:ENSMUST00000006629(transcript)|ensembl:ENSMUST00000011877(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008091"(spectrin)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030673"(axolemma)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031430"(M band)|go:"GO:0032437"(cuticular plate)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0071709"(membrane assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|interpro:IPR041681|mint:Q62261|rcsb pdb:1BTN|rcsb pdb:1MPH|rcsb pdb:6M3P|reactome:R-MMU-375165|reactome:R-MMU-445095|reactome:R-MMU-5673001|reactome:R-MMU-6807878|reactome:R-MMU-9013420|reactome:R-MMU-9013424|refseq:NP_033286.2|refseq:NP_787030.2|refseq:XP_006514662.1|refseq:XP_006514663.1|dip:DIP-31558N|hgnc:"MGI:98388"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:N6xVFU+ocY6PXsIz5ZIsA05bGPs10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P16546	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-911063|uniprotkb:A3KGU6|uniprotkb:Q8K380|uniprotkb:Q9CT05|uniprotkb:A3KGU8|ensembl:ENSMUSP00000092697	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:sptn1_mouse(display_long)|uniprotkb:Alpha-II spectrin(gene name synonym)|uniprotkb:Fodrin alpha chain(gene name synonym)|uniprotkb:Sptan1(gene name)|psi-mi:Sptan1(display_short)|uniprotkb:Spna2(gene name synonym)|uniprotkb:Spta2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	dip:DIP-37712N|ensembl:ENSMUSG00000057738(gene)|ensembl:ENSMUST00000095083(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005916"(fascia adherens)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030018"(Z disc)|go:"GO:0030507"(spectrin binding)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032437"(cuticular plate)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033270"(paranode region of axon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051693"(actin filament capping)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035825|interpro:IPR036028|mint:P16546|reactome:R-MMU-264870|reactome:R-MMU-375165|reactome:R-MMU-445095|reactome:R-MMU-5673001|reactome:R-MMU-6798695|reactome:R-MMU-6807878|reactome:R-MMU-9013420|reactome:R-MMU-9013424|hgnc:"MGI:98386"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:UVB6Kv+PBlqDH3OLoGjxm5oYVPQ10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P63318	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-397096|uniprotkb:P05697|ensembl:ENSMUSP00000097874	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:kpcg_mouse(display_long)|uniprotkb:Pkcc(gene name synonym)|uniprotkb:Pkcg(gene name synonym)|uniprotkb:Prkcc(gene name synonym)|uniprotkb:Prkcg(gene name)|psi-mi:Prkcg(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_035232.1|ensembl:ENSMUSG00000078816(gene)|ensembl:ENSMUST00000100301(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0032095"(regulation of response to food)|go:"GO:0032425"(positive regulation of mismatch repair)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0043278"(response to morphine)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0044305"(calyx of Held)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048265"(response to pain)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060384"(innervation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0099171"(presynaptic modulation of chemical synaptic transmission)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:0005829"(cytosol)|go:"GO:1990911"(response to psychosocial stress)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014375(Protein kinase C, alpha/beta/gamma types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030425"(dendrite)|go:"GO:0031397"(negative regulation of protein ubiquitination)|interpro:IPR020454|interpro:IPR035892|mint:P63318|reactome:R-MMU-111933|reactome:R-MMU-114516|reactome:R-MMU-416993|reactome:R-MMU-5099900|reactome:R-MMU-76005|hgnc:"MGI:97597"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:t4ukCPPAnYUtHCH1hnQE+uiyfEM10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P17918	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-1173716|ensembl:ENSMUSP00000028817	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:pcna_mouse(display_long)|uniprotkb:Pcna(gene name)|psi-mi:Pcna(display_short)|uniprotkb:Cyclin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005813"(centrosome)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006298"(mismatch repair)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0000701"(purine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0032077"(positive regulation of deoxyribonuclease activity)|go:"GO:0032139"(dinucleotide insertion or deletion binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0033993"(response to lipid)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0043626"(PCNA complex)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0097421"(liver regeneration)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902990"(mitotic telomere maintenance via semi-conservative replication)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|mint:P17918|reactome:R-MMU-110312|go:"GO:0035035"(histone acetyltransferase binding)|reactome:R-MMU-110314|reactome:R-MMU-110320|reactome:R-MMU-174411|reactome:R-MMU-174414|reactome:R-MMU-174417|reactome:R-MMU-174437|reactome:R-MMU-4615885|reactome:R-MMU-5358565|reactome:R-MMU-5651801|reactome:R-MMU-5655862|reactome:R-MMU-5656121|reactome:R-MMU-5656169|reactome:R-MMU-5685942|reactome:R-MMU-5696397|reactome:R-MMU-5696400|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-6804114|reactome:R-MMU-69091|ensembl:ENSMUSG00000027342(gene)|ensembl:ENSMUST00000028817(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|refseq:NP_035175.1|reactome:R-MMU-69166|reactome:R-MMU-69183|reactome:R-MMU-8866654|dip:DIP-39409N|hgnc:"MGI:97503"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:AREQR8Nveu4uamAlZuOEwlnDDec10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P08553	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-445188|uniprotkb:A2VCT5|uniprotkb:Q0VDM8|uniprotkb:Q3HRJ6|uniprotkb:Q3TNS4|uniprotkb:Q3TPK2|uniprotkb:Q61961|uniprotkb:Q8BQ20	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:nfm_mouse(display_long)|uniprotkb:Neurofilament triplet M protein(gene name synonym)|uniprotkb:160 kDa neurofilament protein(gene name synonym)|uniprotkb:Neurofilament 3(gene name synonym)|uniprotkb:Nefm(gene name)|psi-mi:Nefm(display_short)|uniprotkb:Nef3(gene name synonym)|uniprotkb:Nfm(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_032717.2|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR002957(Keratin, type I)|interpro:IPR039008|interpro:IPR027697|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005883"(neurofilament)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015643"(toxic substance binding)|go:"GO:0030424"(axon)|go:"GO:0031133"(regulation of axon diameter)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045105"(intermediate filament polymerization or depolymerization)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099182"(presynaptic intermediate filament cytoskeleton)|mint:P08553|hgnc:"MGI:97314"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:2HBUZIEhbbrfamAhbq7gyuRUaTk10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P08551	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-445199|uniprotkb:Q8K0Z0|ensembl:ENSMUSP00000022639	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:nfl_mouse(display_long)|uniprotkb:Neurofilament triplet L protein(gene name synonym)|uniprotkb:68 kDa neurofilament protein(gene name synonym)|uniprotkb:Nefl(gene name)|psi-mi:Nefl(display_short)|uniprotkb:Nfl(gene name synonym)|uniprotkb:Nf68(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_035040.1|ensembl:ENSMUSG00000022055(gene)|ensembl:ENSMUST00000022639(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0005883"(neurofilament)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099182"(presynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1903935"(response to sodium arsenite)|go:"GO:1903937"(response to acrylamide)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027692|interpro:IPR039008|mint:P08551|reactome:R-MMU-438066|reactome:R-MMU-5673001|go:"GO:0098981"(cholinergic synapse)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031133"(regulation of axon diameter)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045105"(intermediate filament polymerization or depolymerization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051258"(protein polymerization)|go:"GO:0051412"(response to corticosterone)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0060074"(synapse maturation)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|dip:DIP-31944N|hgnc:"MGI:97313"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:E8KK2ppZXyLXIlFZp/pjXv7GBEU10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P46660	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-400482|uniprotkb:Q61958|uniprotkb:Q8VCW5|ensembl:ENSMUSP00000041347	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:ainx_mouse(display_long)|uniprotkb:Ina(gene name)|psi-mi:Ina(display_short)|uniprotkb:66 kDa neurofilament protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_666212.3|ensembl:ENSMUSG00000034336(gene)|ensembl:ENSMUST00000037636(transcript)|go:"GO:0005883"(neurofilament)|go:"GO:0007399"(nervous system development)|go:"GO:0030154"(cell differentiation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027703|interpro:IPR039008|mint:P46660|hgnc:"MGI:96568"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:amjP0AajB8s2oXmV96wzyfz6evE10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P62874	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-357152|ensembl:ENSMUSP00000030940|ensembl:ENSMUSP00000101241|ensembl:ENSMUSP00000130123|ensembl:ENSMUSP00000135091|uniprotkb:P04901|uniprotkb:P04697	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:gbb1_mouse(display_long)|uniprotkb:Gnb1(gene name)|psi-mi:Gnb1(display_short)|uniprotkb:Transducin beta chain 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000029064(gene)|ensembl:ENSMUST00000030940(transcript)|ensembl:ENSMUST00000105616(transcript)|ensembl:ENSMUST00000165335(transcript)|ensembl:ENSMUST00000176637(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007603"(phototransduction, visible light)|reactome:R-MMU-9009391|reactome:R-MMU-997272|reactome:R-MMU-8964616|go:"GO:0010659"(cardiac muscle cell apoptotic process)|go:"GO:0030425"(dendrite)|go:"GO:0008283"(cell population proliferation)|go:"GO:0030507"(spectrin binding)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0042622"(photoreceptor outer segment membrane)|go:"GO:0043209"(myelin sheath)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047391"(alkylglycerophosphoethanolamine phosphodiesterase activity)|go:"GO:0050909"(sensory perception of taste)|go:"GO:0051020"(GTPase binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P62874|rcsb pdb:6K41|rcsb pdb:6K42|rcsb pdb:6RMV|reactome:R-MMU-1296041|reactome:R-MMU-202040|reactome:R-MMU-2485179|reactome:R-MMU-381676|reactome:R-MMU-381753|reactome:R-MMU-392170|reactome:R-MMU-392451|reactome:R-MMU-392851|reactome:R-MMU-400042|reactome:R-MMU-4086398|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-418217|reactome:R-MMU-418555|reactome:R-MMU-418592|reactome:R-MMU-418594|reactome:R-MMU-418597|reactome:R-MMU-420092|reactome:R-MMU-428930|reactome:R-MMU-432040|reactome:R-MMU-456926|reactome:R-MMU-500657|reactome:R-MMU-6814122|reactome:R-MMU-8964315|refseq:NP_001153488.1|refseq:NP_001153489.1|refseq:NP_032168.1|refseq:XP_017175466.1|hgnc:"MGI:95781"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:zP/G70MXiSQpzbyyWFTWrJFQENk10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P21279	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-771975|uniprotkb:Q6PFF5|ensembl:ENSMUSP00000025541	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:gnaq_mouse(display_long)|uniprotkb:Guanine nucleotide-binding protein alpha-q(gene name synonym)|uniprotkb:Gnaq(gene name)|psi-mi:Gnaq(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_032165.3|dip:DIP-606N|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045634"(regulation of melanocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0047391"(alkylglycerophosphoethanolamine phosphodiesterase activity)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|interpro:IPR000654(G-protein alpha subunit, group Q)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P21279|rcsb pdb:2BCJ|rcsb pdb:2RGN|rcsb pdb:3AH8|rcsb pdb:3OHM|rcsb pdb:4EKC|rcsb pdb:4EKD|rcsb pdb:4GNK|rcsb pdb:4QJ3|rcsb pdb:4QJ4|rcsb pdb:4QJ5|rcsb pdb:5DO9|reactome:R-MMU-112043|reactome:R-MMU-202040|reactome:R-MMU-399997|reactome:R-MMU-416476|reactome:R-MMU-418592|reactome:R-MMU-428930|reactome:R-MMU-434316|reactome:R-MMU-456926|reactome:R-MMU-6814122|go:"GO:0044297"(cell body)|ensembl:ENSMUSG00000024639(gene)|ensembl:ENSMUST00000025541(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001508"(action potential)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016020"(membrane)|go:"GO:0016322"(neuron remodeling)|go:"GO:0021884"(forebrain neuron development)|go:"GO:0030425"(dendrite)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031826"(type 2A serotonin receptor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042711"(maternal behavior)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043267"(negative regulation of potassium ion transport)|hgnc:"MGI:95776"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:7HfYjIynxSexMzn1uUS6x4sfzbI10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P18872	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-771950|uniprotkb:P18873|intact:EBI-1018769|ensembl:ENSMUSP00000034198|ensembl:ENSMUSP00000114144	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:gnao_mouse(display_long)|uniprotkb:Gnao1(gene name)|psi-mi:Gnao1(display_short)|uniprotkb:Gna0(gene name synonym)|uniprotkb:Gnao(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001106855.1|refseq:NP_034438.1|dip:DIP-29921N|ensembl:ENSMUSG00000031748(gene)|ensembl:ENSMUST00000034198(transcript)|ensembl:ENSMUST00000125716(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0007568"(aging)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0009987"(cellular process)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030900"(forebrain development)|go:"GO:0031175"(neuron projection development)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034097"(response to cytokine)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043005"(neuron projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0043278"(response to morphine)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044297"(cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0051430"(corticotropin-releasing hormone receptor 1 binding)|go:"GO:0051926"(negative regulation of calcium ion transport)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P18872|rcsb pdb:3C7K|reactome:R-MMU-4086398|hgnc:"MGI:95775"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:CCww9l5owYxGicswRXjsSu6Y+5g10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:B2RSH2	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-2308910|ensembl:ENSMUSP00000074259	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:gnai1_mouse(display_long)|uniprotkb:Gnai1(gene name)|psi-mi:Gnai1(display_short)|uniprotkb:Gnai-1(gene name synonym)|uniprotkb:Adenylate cyclase-inhibiting G alpha protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_034435.1|ensembl:ENSMUSG00000057614(gene)|ensembl:ENSMUST00000074694(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045121"(membrane raft)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0099738"(cell cortex region)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-MMU-170670|reactome:R-MMU-392170|reactome:R-MMU-400042|reactome:R-MMU-418594|reactome:R-MMU-9009391|hgnc:"MGI:95771"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:3yQOCXJb8Undp/Xw42xrBiG5ePE10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P21278	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-15571625|ensembl:ENSMUSP00000043190|uniprotkb:Q61939	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:gna11_mouse(display_long)|uniprotkb:Gna11(gene name)|psi-mi:Gna11(display_short)|uniprotkb:Gna-11(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000034781(gene)|ensembl:ENSMUST00000043604(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001508"(action potential)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031826"(type 2A serotonin receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045634"(regulation of melanocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0047391"(alkylglycerophosphoethanolamine phosphodiesterase activity)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|go:"GO:0071467"(cellular response to pH)|interpro:IPR000654(G-protein alpha subunit, group Q)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-MMU-112043|reactome:R-MMU-202040|reactome:R-MMU-399997|reactome:R-MMU-416476|reactome:R-MMU-418592|reactome:R-MMU-428930|reactome:R-MMU-434316|reactome:R-MMU-456926|reactome:R-MMU-6814122|refseq:NP_034431.1|dip:DIP-603N|hgnc:"MGI:95766"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:HzMrR557jIl9sHKzMotEP37fuFI10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P15105	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-444858|uniprotkb:Q3TRK7|uniprotkb:Q64432|uniprotkb:Q91VC6|ensembl:ENSMUSP00000083375|ensembl:ENSMUSP00000123157	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:glna_mouse(display_long)|uniprotkb:Glutamate--ammonia ligase(gene name synonym)|uniprotkb:Glul(gene name)|psi-mi:Glul(display_short)|uniprotkb:Glns(gene name synonym)|uniprotkb:Palmitoyltransferase GLUL(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_032157.2|go:"GO:0030145"(manganese ion binding)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043679"(axon terminus)|go:"GO:0044297"(cell body)|go:"GO:0045503"(dynein light chain binding)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0097386"(glial cell projection)|go:"GO:1903670"(regulation of sprouting angiogenesis)|go:"GO:1904749"(regulation of protein localization to nucleolus)|interpro:IPR008146(Glutamine synthetase, catalytic region)|interpro:IPR008147(Glutamine synthetase, beta-Grasp)|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR027302|interpro:IPR027303|interpro:IPR036651|mint:P15105|reactome:R-MMU-210455|reactome:R-MMU-8964539|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|ensembl:ENSMUSG00000026473(gene)|ensembl:ENSMUST00000086199(transcript)|ensembl:ENSMUST00000140685(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0004356"(glutamate-ammonia ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0006542"(glutamine biosynthetic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009749"(response to glucose)|go:"GO:0010594"(regulation of endothelial cell migration)|go:"GO:0016595"(glutamate binding)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019676"(ammonia assimilation cycle)|hgnc:"MGI:95739"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:j6R9fxGLKpiREWpecpdnBY9ftoo10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P35922	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-645094	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:fmr1_mouse(display_long)|uniprotkb:Fmr1(gene name)|psi-mi:Fmr1(display_short)|uniprotkb:Fmr-1(gene name synonym)|uniprotkb:Fragile X mental retardation protein 1 homolog(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032196|interpro:IPR040472|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015030"(Cajal body)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030371"(translation repressor activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034046"("poly(G) binding")|go:"GO:0034644"(cellular response to UV)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043679"(axon terminus)|go:"GO:0003723"(RNA binding)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000301"(negative regulation of synaptic vesicle exocytosis)|go:"GO:2000766"(negative regulation of cytoplasmic translation)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048170"(positive regulation of long-term neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051028"(mRNA transport)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0060996"(dendritic spine development)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070840"(dynein complex binding)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0097386"(glial cell projection)|go:"GO:0097444"(spine apparatus)|go:"GO:0098586"(cellular response to virus)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099577"(regulation of translation at presynapse, modulating synaptic transmission)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1900453"(negative regulation of long-term synaptic depression)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1901254"(positive regulation of intracellular transport of viral material)|go:"GO:1901386"(negative regulation of voltage-gated calcium channel activity)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1902373"(negative regulation of mRNA catabolic process)|go:"GO:1902416"(positive regulation of mRNA binding)|go:"GO:1902737"(dendritic filopodium)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905244"(regulation of modification of synaptic structure)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990635"(proximal dendrite)|go:"GO:1990812"(growth cone filopodium)|go:"GO:0044297"(cell body)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0007417"(central nervous system development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0010369"(chromocenter)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010955"(negative regulation of protein processing)|mint:P35922|interpro:IPR036612|interpro:IPR040148|interpro:IPR041560|hgnc:"MGI:95564"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:/NR92KtQt5zwsa+U6lel3sXQyu810090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:O08919	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-773000|uniprotkb:Q4QQQ2|uniprotkb:Q6NVG8|ensembl:ENSMUSP00000078245	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:numbl_mouse(display_long)|uniprotkb:Numbl(gene name)|psi-mi:Numbl(display_short)|uniprotkb:Nbl(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_035080.2|ensembl:ENSMUSG00000063160(gene)|ensembl:ENSMUST00000079258(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007409"(axonogenesis)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019538"(protein metabolic process)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021849"(neuroblast division in subventricular zone)|go:"GO:0030900"(forebrain development)|go:"GO:0034332"(adherens junction organization)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR010449(NUMB phenylalanine-rich)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016698(Numb/numb-like)|hgnc:"MGI:894702"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:2qFX1x26D9ZwQAsK/wDEwyevlD410090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P70398	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-2214043|uniprotkb:E9QLY0|uniprotkb:Q62497	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:usp9x_mouse(display_long)|uniprotkb:Ubiquitin thioesterase FAF-X(gene name synonym)|uniprotkb:Usp9x(gene name)|psi-mi:Usp9x(display_short)|uniprotkb:Fafl(gene name synonym)|uniprotkb:Fam(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease FAF-X(gene name synonym)|uniprotkb:Deubiquitinating enzyme FAF-X(gene name synonym)|uniprotkb:Fat facets protein-related, X-linked(gene name synonym)|uniprotkb:Ubiquitin-specific protease 9, X chromosome(gene name synonym)|uniprotkb:Ubiquitin carboxyl-terminal hydrolase FAM(gene name synonym)|uniprotkb:Fat facets homolog(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	interpro:IPR016024(Armadillo-type fold)|interpro:IPR028889|refseq:NP_033507.2|interpro:IPR018200|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|mint:P70398|interpro:IPR038765|interpro:IPR021905|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001764"(neuron migration)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016477"(cell migration)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021698"(cerebellar cortex structural organization)|go:"GO:0021766"(hippocampus development)|go:"GO:0030426"(growth cone)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045177"(apical part of cell)|go:"GO:0048511"(rhythmic process)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0051301"(cell division)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071947"(protein deubiquitination involved in ubiquitin-dependent protein catabolic process)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|reactome:R-MMU-2173795|reactome:R-MMU-5689880|reactome:R-MMU-8866652|reactome:R-MMU-9013420|reactome:R-MMU-9013424|reactome:R-MMU-9033241|hgnc:"MGI:894681"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:QXx5gkd+PxoNgIj2b2dLjpCuNr410090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:O54833	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-1216452|ensembl:ENSMUSP00000055919|ensembl:ENSMUSP00000148404	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:csk22_mouse(display_long)|uniprotkb:Csnk2a2(gene name)|psi-mi:Csnk2a2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_034104.1|ensembl:ENSMUSG00000046707(gene)|ensembl:ENSMUST00000056919(transcript)|ensembl:ENSMUST00000212214(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0031519"(PcG protein complex)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:O54833|reactome:R-MMU-1483191|reactome:R-MMU-201688|reactome:R-MMU-2514853|reactome:R-MMU-445144|reactome:R-MMU-6804756|reactome:R-MMU-6814122|reactome:R-MMU-8934903|reactome:R-MMU-8939243|reactome:R-MMU-8948751|hgnc:"MGI:88547"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:6aE12BakwtzXfYRZ4EwCGSG5wBE10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q923T9	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-771638|uniprotkb:Q3U3H3|uniprotkb:Q8VED3|ensembl:ENSMUSP00000071720	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:kcc2g_mouse(display_long)|uniprotkb:Camk2g(gene name)|psi-mi:Camk2g(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001034227.1|refseq:NP_001034228.1|refseq:NP_848712.2|ensembl:ENSMUSG00000021820(gene)|ensembl:ENSMUST00000071816(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030154"(cell differentiation)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901897"(regulation of relaxation of cardiac muscle)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|mint:Q923T9|reactome:R-MMU-3371571|reactome:R-MMU-399719|reactome:R-MMU-438066|reactome:R-MMU-5576892|reactome:R-MMU-5578775|reactome:R-MMU-5673000|reactome:R-MMU-5673001|reactome:R-MMU-877300|reactome:R-MMU-936837|hgnc:"MGI:88259"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:pbJqcEUQJQRnAwcKozmS72n9s1w10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P28652	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-397029|uniprotkb:Q5SVH9|ensembl:ENSMUSP00000105438|ensembl:ENSMUSP00000105440	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:kcc2b_mouse(display_long)|uniprotkb:Camk2b(gene name)|psi-mi:Camk2b(display_short)|uniprotkb:Camk2d(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_031621.3|ensembl:ENSMUSG00000057897(gene)|ensembl:ENSMUST00000109813(transcript)|ensembl:ENSMUST00000109815(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030425"(dendrite)|go:"GO:0032222"(regulation of synaptic transmission, cholinergic)|go:"GO:0032430"(positive regulation of phospholipase A2 activity)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0002030"(inhibitory G protein-coupled receptor phosphorylation)|go:"GO:0043274"(phospholipase binding)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051233"(spindle midzone)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060466"(activation of meiosis involved in egg activation)|reactome:R-MMU-438066|reactome:R-MMU-5576892|reactome:R-MMU-5578775|reactome:R-MMU-5673000|reactome:R-MMU-5673001|reactome:R-MMU-877300|reactome:R-MMU-936837|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:2001222"(regulation of neuron migration)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|mint:P28652|reactome:R-MMU-3371571|reactome:R-MMU-399719|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|dip:DIP-31582N|hgnc:"MGI:88257"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:di/l1bhtPhzeKpErP6iyQfFypBo10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P11798	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-400384|uniprotkb:Q61284|uniprotkb:Q6ZWN4|ensembl:ENSMUSP00000099952	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:kcc2a_mouse(display_long)|uniprotkb:Camk2a(gene name)|psi-mi:Camk2a(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_033922.1|refseq:NP_803126.1|refseq:NP_001273738.1|ensembl:ENSMUSG00000024617(gene)|ensembl:ENSMUST00000102888(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060996"(dendritic spine development)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099004"(calmodulin dependent kinase signaling pathway)|go:"GO:0099148"(regulation of synaptic vesicle docking)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099573"(glutamatergic postsynaptic density)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990443"(peptidyl-threonine autophosphorylation)|go:"GO:2000124"(regulation of endocannabinoid signaling pathway)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|mint:P11798|rcsb pdb:1HKX|rcsb pdb:4X3I|rcsb pdb:6TS3|reactome:R-MMU-3371571|reactome:R-MMU-399719|reactome:R-MMU-4086398|reactome:R-MMU-438066|reactome:R-MMU-5576892|reactome:R-MMU-5578775|reactome:R-MMU-5673000|reactome:R-MMU-5673001|reactome:R-MMU-877300|reactome:R-MMU-936837|dip:DIP-31593N|hgnc:"MGI:88256"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:mHdSlhGhe3sMOyO+YGwROtGOGfY10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P07356	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-738510|ensembl:ENSMUSP00000034756	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:anxa2_mouse(display_long)|uniprotkb:Anxa2(gene name)|psi-mi:Anxa2(display_short)|uniprotkb:Anx2(gene name synonym)|uniprotkb:Cal1h(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_031611.1|refseq:XP_006510859.1|ensembl:ENSMUSG00000032231(gene)|ensembl:ENSMUST00000034756(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044147"(negative regulation of formation of structure involved in a symbiotic process)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0052362"(obsolete catabolism by host of symbiont protein)|go:"GO:0052405"|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07356|rcsb pdb:4HRE|reactome:R-MMU-6798695|reactome:R-MMU-75205|hgnc:"MGI:88246"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:R7GyK+r4KmwX28VH2qQZF+Y729A10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P14094	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-770851|ensembl:ENSMUSP00000027863	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837|hgnc:"MGI:88108"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q8C8R3	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-774322|intact:EBI-2133064|uniprotkb:Q6PCN2|uniprotkb:Q3TM62|uniprotkb:Q3V2X0|uniprotkb:Q80ZZ7|uniprotkb:Q8BNC1|uniprotkb:Q8C445|uniprotkb:Q8CCV0|intact:EBI-2255612|intact:EBI-8314005|intact:MINT-4115219	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:ank2_mouse(display_long)|uniprotkb:Brain ankyrin(gene name synonym)|uniprotkb:AnkB(gene name synonym)|uniprotkb:Ank2(gene name)|psi-mi:Ank2(display_short)|uniprotkb:Ankyrin-B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001029340.1|refseq:NP_848770.2|dip:DIP-58645N|mint:Q8C8R3|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006897"(endocytosis)|go:"GO:0008104"(protein localization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0015031"(protein transport)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031430"(M band)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031672"(A band)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034613"(cellular protein localization)|go:"GO:0036309"(protein localization to M-band)|go:"GO:0036371"(protein localization to T-tubule)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086015"(SA node cell action potential)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086066"(atrial cardiac muscle cell to AV node cell communication)|go:"GO:0086070"(SA node cell to atrial cardiac muscle cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901021"(positive regulation of calcium ion transmembrane transporter activity)|go:"GO:2001257"(regulation of cation channel activity)|go:"GO:2001259"(positive regulation of cation channel activity)|interpro:IPR000488(Death)|interpro:IPR000906(ZU5)|interpro:IPR002110(Ankyrin)|interpro:IPR011029(DEATH-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR040745|hgnc:"MGI:88025"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:SkB13oxZVcKuMnI8r5ItFIq2pXQ10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q6PAK3	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16750729|ensembl:ENSMUSP00000032500|uniprotkb:Q7M6Z2	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:anm8_mouse(display_long)|uniprotkb:Prmt8(gene name)|psi-mi:Prmt8(display_short)|uniprotkb:Hrmt1l4(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000030350(gene)|ensembl:ENSMUST00000032500(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006479"(protein methylation)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019919"(peptidyl-arginine methylation, to asymmetrical-dimethyl arginine)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0098753"(anchored component of the cytoplasmic side of the plasma membrane)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR025799|interpro:IPR029063|refseq:NP_958759.2|hgnc:"MGI:3043083"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:3qppTxc3fi+yO9cm2r8BtxMsW0010090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q920P5	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-6271652|ensembl:ENSMUSP00000042785	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:kad5_mouse(display_long)|uniprotkb:Ak5(gene name)|psi-mi:Ak5(display_short)|uniprotkb:ATP-AMP transphosphorylase 5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000039058(gene)|ensembl:ENSMUST00000045262(transcript)|go:"GO:0004017"(adenylate kinase activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006165"(nucleoside diphosphate phosphorylation)|go:"GO:0009142"(nucleoside triphosphate biosynthetic process)|go:"GO:0034451"(centriolar satellite)|go:"GO:0046034"(ATP metabolic process)|interpro:IPR000850(Adenylate kinase)|interpro:IPR006267(Adenylate kinase, isozyme 1)|interpro:IPR027417|interpro:IPR033690|reactome:R-MMU-499943|refseq:NP_001074746.1|hgnc:"MGI:2677491"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:Iv5BXlvLvqFnjHarEpnC9RJzKSw10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q80YA9	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-771429|uniprotkb:Q80TP2|ensembl:ENSMUSP00000026750	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:cnkr2_mouse(display_long)|uniprotkb:Cnksr2(gene name)|psi-mi:Cnksr2(display_short)|uniprotkb:Kiaa0902(gene name synonym)|uniprotkb:CNK homolog protein 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_808419.1|refseq:NP_001297648.1|ensembl:ENSMUSG00000025658(gene)|ensembl:ENSMUST00000026750(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099173"(postsynapse organization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010599(Connector enhancer of kinase suppressor of ras 2)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017874|interpro:IPR036034|reactome:R-MMU-5674135|hgnc:"MGI:2661175"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:bG3fvfM0wtqno1U+KQTLvhm6btA10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q2M3X8	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-2931675|ensembl:ENSMUSP00000115207|ensembl:ENSMUSP00000122232|uniprotkb:G5E8P7|uniprotkb:B1B1B5|uniprotkb:B1B1B6|uniprotkb:B1B1B7|uniprotkb:Q80VL9|uniprotkb:Q8C873	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:phar1_mouse(display_long)|uniprotkb:Phactr1(gene name)|psi-mi:Phactr1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000054728(gene)|ensembl:ENSMUST00000128646(transcript)|ensembl:ENSMUST00000149235(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0045202"(synapse)|go:"GO:0048870"(cell motility)|go:"GO:0140059"(dendrite arborization)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR004018(RPEL repeat)|interpro:IPR029987|rcsb pdb:4B1U|rcsb pdb:4B1V|rcsb pdb:4B1W|rcsb pdb:4B1X|rcsb pdb:4B1Y|rcsb pdb:4B1Z|refseq:XP_011242697.1|refseq:NP_001005740.1|refseq:XP_017170971.1|refseq:XP_017170972.1|refseq:NP_001289564.1|refseq:NP_001289565.1|refseq:XP_006516968.1|refseq:XP_006516969.1|hgnc:"MGI:2659021"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:S82qOO2lYBH7U4x+tq9ZTibCim410090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q6U7H8	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16750703|ensembl:ENSMUSP00000051282|uniprotkb:A2ASY7|uniprotkb:A2ASY9|uniprotkb:Q3TNU0|uniprotkb:Q3V0C8|uniprotkb:Q52KH3|uniprotkb:Q8K345	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:pi5l1_mouse(display_long)|uniprotkb:Pip5kl1(gene name)|psi-mi:Pip5kl1(display_short)|uniprotkb:Pipkh(gene name synonym)|uniprotkb:Phosphatidylinositol phosphate kinase homolog(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000046854(gene)|ensembl:ENSMUST00000055304(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0016308"(1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042995"(cell projection)|go:"GO:0043065"(positive regulation of apoptotic process)|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027484|refseq:NP_937834.1|hgnc:"MGI:2448520"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:A1lg4/zQvO4mhMmlcD898JiD6Bc10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q6P4S6	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-2931619|uniprotkb:Q641L5|uniprotkb:Q66JZ5|uniprotkb:Q6ZQ09|uniprotkb:Q8K075|uniprotkb:Q9CYD5	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:sik3_mouse(display_long)|uniprotkb:Sik3(gene name)|psi-mi:Sik3(display_short)|uniprotkb:Kiaa0999(gene name synonym)|uniprotkb:Qsk(gene name synonym)|uniprotkb:Salt-inducible kinase 3(gene name synonym)|uniprotkb:Serine/threonine-protein kinase QSK(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001958"(endochondral ossification)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0060351"(cartilage development involved in endochondral bone morphogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1904515"(positive regulation of TORC2 signaling)|refseq:NP_081774.3|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR034672|hgnc:"MGI:2446296"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:eIUTh+NVsTk8OSsys+A7gFfS9AM10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q8C078	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-937199|uniprotkb:Q80TS0|uniprotkb:Q8BXM8|uniprotkb:Q8C0G3|uniprotkb:Q8CH42|uniprotkb:Q8QZT7|ensembl:ENSMUSP00000107297	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:kkcc2_mouse(display_long)|uniprotkb:Camkk2(gene name)|psi-mi:Camkk2(display_short)|uniprotkb:Kiaa0787(gene name synonym)|uniprotkb:Calcium/calmodulin-dependent protein kinase kinase beta(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001186605.1|refseq:NP_663333.1|refseq:XP_006530293.1|refseq:XP_006530294.1|refseq:XP_017176252.1|ensembl:ENSMUSG00000029471(gene)|ensembl:ENSMUST00000111668(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0043005"(neuron projection)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0061762"(CAMKK-AMPK signaling cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q8C078|reactome:R-MMU-111932|reactome:R-MMU-442729|reactome:R-MMU-9619229|hgnc:"MGI:2444812"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:sfp+8Ypk+JBYWVwzYsGqAXqZVTY10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:E1U8D0	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16728709	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:soga1_mouse(display_long)|uniprotkb:SOGA family member 1(gene name synonym)|uniprotkb:Suppressor of glucose by autophagy(gene name synonym)|uniprotkb:Suppressor of glucose, autophagy-associated protein 1(gene name synonym)|uniprotkb:Soga1(gene name)|psi-mi:Soga1(display_short)|uniprotkb:Soga(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	go:"GO:0005615"(extracellular space)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0045721"(negative regulation of gluconeogenesis)|interpro:IPR027882|interpro:IPR027881|hgnc:"MGI:2444575"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:Kk7DCpjGgjPDQ/NrzlscsMuBDGg10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q8BSS9	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-3647690|uniprotkb:Q6P1D2|uniprotkb:Q8BN73	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:lipa2_mouse(display_long)|uniprotkb:Ppfia2(gene name)|psi-mi:Ppfia2(display_short)|uniprotkb:Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	interpro:IPR037620|interpro:IPR037621|interpro:IPR037622|refseq:NP_796347.2|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR030441|interpro:IPR029515|go:"GO:0009986"(cell surface)|go:"GO:0030424"(axon)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099181"(structural constituent of presynapse)|go:"GO:0099519"(dense core granule cytoskeletal transport)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|reactome:R-MMU-181429|reactome:R-MMU-181430|reactome:R-MMU-210500|reactome:R-MMU-212676|reactome:R-MMU-264642|reactome:R-MMU-388844|hgnc:"MGI:2443834"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:BFzvFf0HS/TtzaUkV23/oW32KAo10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q68FD5	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-769168|ensembl:ENSMUSP00000099475	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:clh1_mouse(display_long)|uniprotkb:Cltc(gene name)|psi-mi:Cltc(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001003908.1|dip:DIP-31947N|ensembl:ENSMUSG00000047126(gene)|ensembl:ENSMUST00000103186(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030118"(clathrin coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031523"(Myb complex)|go:"GO:0031623"(receptor internalization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042277"(peptide binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|mint:Q68FD5|rcsb pdb:5ODS|reactome:R-MMU-177504|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2132295|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-437239|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8866427|reactome:R-MMU-8964038|reactome:R-MMU-9013420|reactome:R-MMU-9013424|go:"GO:0032051"(clathrin light chain binding)|hgnc:"MGI:2388633"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:iHg/TOG2rWePqtsEmuc/szn/chI10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q9EQZ7	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16750656|ensembl:ENSMUSP00000080711|uniprotkb:Q8C433|uniprotkb:Q8CCK2	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:rims2_mouse(display_long)|uniprotkb:Rims2(gene name)|psi-mi:Rims2(display_short)|uniprotkb:Rab3ip2(gene name synonym)|uniprotkb:Rim2(gene name synonym)|uniprotkb:Rab-3-interacting molecule 2(gene name synonym)|uniprotkb:Rab-3-interacting protein 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000037386(gene)|ensembl:ENSMUST00000082054(transcript)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030073"(insulin secretion)|go:"GO:0030154"(cell differentiation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0061669"(spontaneous neurotransmitter secretion)|go:"GO:0097151"(positive regulation of inhibitory postsynaptic potential)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010911(Rab-binding)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR030631|interpro:IPR035892|interpro:IPR036034|interpro:IPR039032|interpro:IPR041282|interpro:IPR041489|refseq:NP_001243313.1|refseq:NP_444501.1|hgnc:"MGI:2152972"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:f4+bYOeorIL8Jdv6FQ5kxcqo+M410090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q99NE5	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-775541|uniprotkb:Q5DU35|uniprotkb:Q5J8K0|uniprotkb:Q5J8K1|uniprotkb:Q5J8K2|uniprotkb:Q5J8K3|uniprotkb:Q5J8K4	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:rims1_mouse(display_long)|uniprotkb:Rab-3-interacting molecule 1(gene name synonym)|uniprotkb:Rab-3-interacting protein 1(gene name synonym)|uniprotkb:Rims1(gene name)|psi-mi:Rims1(display_short)|uniprotkb:Rab3ip1(gene name synonym)|uniprotkb:Rim1(gene name synonym)|uniprotkb:Kiaa0340(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001012641.1|refseq:NP_001012642.1|refseq:NP_001012643.1|refseq:NP_444500.1|refseq:NP_898839.2|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010911(Rab-binding)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR039032|interpro:IPR035892|interpro:IPR036034|interpro:IPR041282|reactome:R-MMU-181429|reactome:R-MMU-181430|reactome:R-MMU-210500|reactome:R-MMU-212676|reactome:R-MMU-264642|reactome:R-MMU-888590|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010808"(positive regulation of synaptic vesicle priming)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031982"(vesicle)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060478"(acrosomal vesicle exocytosis)|go:"GO:0061669"(spontaneous neurotransmitter secretion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0097151"(positive regulation of inhibitory postsynaptic potential)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|hgnc:"MGI:2152971"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:EimJngs4cAg6YQgqO36VmSuTlRM10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q812A2	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-2013018|uniprotkb:Q80U09|uniprotkb:Q8BKP4|uniprotkb:Q8BLD0|uniprotkb:Q925I2	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:srgp3_mouse(display_long)|uniprotkb:Srgap3(gene name)|psi-mi:Srgap3(display_short)|uniprotkb:Arhgap14(gene name synonym)|uniprotkb:Kiaa0411(gene name synonym)|uniprotkb:Srgap2(gene name synonym)|uniprotkb:WAVE-associated Rac GTPase-activating protein(gene name synonym)|uniprotkb:Rho GTPase-activating protein 14(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	interpro:IPR031160|refseq:NP_536696.4|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|mint:Q812A2|interpro:IPR035648|interpro:IPR036028|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0030336"(negative regulation of cell migration)|reactome:R-MMU-9013148|reactome:R-MMU-9013149|hgnc:"MGI:2152938"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:rfo/ZKi//Gub/088qDvqLIvgdng10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q80U49	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16728053|ensembl:ENSMUSP00000098580|ensembl:ENSMUSP00000137331|ensembl:ENSMUSP00000152451|uniprotkb:Q3UH33|uniprotkb:Q3UHG1|uniprotkb:Q80UM2	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:c170b_mouse(display_long)|uniprotkb:Centrosomal protein 170B(gene name synonym)|uniprotkb:Cep170b(gene name)|psi-mi:Cep170b(display_short)|uniprotkb:Kiaa0284(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000072825(gene)|ensembl:ENSMUST00000101018(transcript)|ensembl:ENSMUST00000179041(transcript)|ensembl:ENSMUST00000222711(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR029300|refseq:NP_001019773.2|refseq:XP_006515829.1|hgnc:"MGI:2145043"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:vmI/x564L8rTcob6vkmQLu2+JCQ10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q8CG79	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-645416|uniprotkb:Q3UYM7|uniprotkb:Q8K2L5	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:aspp2_mouse(display_long)|uniprotkb:Tumor suppressor p53-binding protein 2(gene name synonym)|uniprotkb:Tp53bp2(gene name)|psi-mi:Tp53bp2(display_short)|uniprotkb:Aspp2(gene name synonym)|uniprotkb:Trp53bp2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_775554.2|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR001452(Src homology-3)|interpro:IPR029071|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007417"(central nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030054"(cell junction)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901216"(positive regulation of neuron death)|interpro:IPR036028|interpro:IPR036770|reactome:R-MMU-6804759|hgnc:"MGI:2138319"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:Ygl3S/FVLP/3gD2F0o5t016B2Bk10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q7TPR4	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-774010|ensembl:ENSMUSP00000021554	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:actn1_mouse(display_long)|uniprotkb:Alpha-actinin cytoskeletal isoform(gene name synonym)|uniprotkb:Non-muscle alpha-actinin-1(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)|uniprotkb:Actn1(gene name)|psi-mi:Actn1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_598917.1|ensembl:ENSMUSG00000015143(gene)|ensembl:ENSMUST00000021554(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005519"(cytoskeletal regulatory protein binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0017166"(vinculin binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030054"(cell junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030220"(platelet formation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0032127"(dense core granule membrane)|go:"GO:0036344"(platelet morphogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0051639"(actin filament network formation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099186"(structural constituent of postsynapse)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:Q7TPR4|rcsb pdb:6C0A|reactome:R-MMU-114608|reactome:R-MMU-446388|reactome:R-MMU-9013405|reactome:R-MMU-9013418|reactome:R-MMU-9035034|hgnc:"MGI:2137706"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:02QPrtqpFY8sgQvjRRI5wmCbNjU10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q9QWI6	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-775592|uniprotkb:O70298	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:srcn1_mouse(display_long)|uniprotkb:p140Cap(gene name synonym)|uniprotkb:SNAP-25-interacting protein(gene name synonym)|uniprotkb:Srcin1(gene name)|psi-mi:Srcin1(display_short)|uniprotkb:Kiaa1684(gene name synonym)|uniprotkb:P140(gene name synonym)|uniprotkb:p130Cas-associated protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_061361.2|interpro:IPR022782|interpro:IPR026727|mint:Q9QWI6|go:"GO:0005737"(cytoplasm)|go:"GO:0006887"(exocytosis)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0098793"(presynapse)|hgnc:"MGI:1933179"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:M3+KJqcvaW0sMG63nFO9CXyjp9Q10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q9R0Q6	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-774003|uniprotkb:Q3UL75|ensembl:ENSMUSP00000031625	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:arc1a_mouse(display_long)|uniprotkb:SOP2-like protein(gene name synonym)|uniprotkb:Sid 329(gene name synonym)|uniprotkb:Arpc1a(gene name)|psi-mi:Arpc1a(display_short)|uniprotkb:Sid329(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_062741.1|ensembl:ENSMUSG00000029621(gene)|ensembl:ENSMUST00000031625(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036195"(muscle cell projection membrane)|go:"GO:0051015"(actin filament binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR030140|interpro:IPR036322|mint:Q9R0Q6|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-5663213|reactome:R-MMU-8856828|hgnc:"MGI:1928896"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:FZAq1/Vf3u+xzNZtYqvrpAKloZs10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q9QY76	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-775792	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:vapb_mouse(display_long)|uniprotkb:VAMP-associated protein 33b(gene name synonym)|uniprotkb:Vapb(gene name)|psi-mi:Vapb(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR016763(Vesicle-associated membrane protein)|reactome:R-MMU-1660661|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044790"(suppression of viral release by host)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|reactome:R-MMU-8980692|reactome:R-MMU-9013106|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013408|hgnc:"MGI:1928744"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:p7R50HS1tQtdk2SEu411MSGLcO410090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q9ES00	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-80579|uniprotkb:Q6DID4|ensembl:ENSMUSP00000099501|uniprotkb:Q9EQE0	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:ube4b_mouse(display_long)|uniprotkb:Ube4b(gene name)|psi-mi:Ube4b(display_short)|uniprotkb:Ufd2(gene name synonym)|uniprotkb:Ubiquitin fusion degradation protein 2(gene name synonym)|uniprotkb:Ufd2a(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase E4 B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000028960(gene)|ensembl:ENSMUST00000103212(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0008626"(granzyme-mediated apoptotic signaling pathway)|go:"GO:0009411"(response to UV)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR003613(U box)|go:"GO:0006457"(protein folding)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|rcsb pdb:2KR4|interpro:IPR019474|refseq:NP_071305.2|hgnc:"MGI:1927086"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:Sl3sl6R637Aw6VcTbxD7IH9sLwM10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q76MZ3	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-400413|ensembl:ENSMUSP00000007708	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:2aaa_mouse(display_long)|uniprotkb:Ppp2r1a(gene name)|psi-mi:Ppp2r1a(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_058587.1|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903538"(regulation of meiotic cell cycle process involved in oocyte maturation)|go:"GO:1990405"(protein antigen binding)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:Q76MZ3|rcsb pdb:2IAE|rcsb pdb:2PF4|rcsb pdb:3FGA|rcsb pdb:6EF4|reactome:R-MMU-113501|reactome:R-MMU-1295596|reactome:R-MMU-141444|reactome:R-MMU-180024|reactome:R-MMU-195253|reactome:R-MMU-196299|reactome:R-MMU-198753|reactome:R-MMU-202670|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-2995383|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-389513|reactome:R-MMU-432142|reactome:R-MMU-4641262|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-5673000|reactome:R-MMU-5675221|reactome:R-MMU-6804757|reactome:R-MMU-6811558|reactome:R-MMU-68877|reactome:R-MMU-69231|reactome:R-MMU-69273|reactome:R-MMU-8854518|reactome:R-MMU-9648025|reactome:R-MMU-975957|ensembl:ENSMUSG00000007564(gene)|ensembl:ENSMUST00000007708(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030425"(dendrite)|go:"GO:0045202"(synapse)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051232"(meiotic spindle elongation)|dip:DIP-29429N|hgnc:"MGI:1926334"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:0tnO11U1SNOOT46j23f7dim8O8k10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q8BIZ1	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16724439|uniprotkb:E9Q644|uniprotkb:Q4KMR9|uniprotkb:Q8BJ47|uniprotkb:Q8BJ49	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:ans1b_mouse(display_long)|uniprotkb:Amyloid-beta protein intracellular domain-associated protein 1(gene name synonym)|uniprotkb:E2A-PBX1-associated protein(gene name synonym)|uniprotkb:Anks1b(gene name)|psi-mi:Anks1b(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	interpro:IPR041880|interpro:IPR041882|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1900383"(regulation of synaptic plasticity by receptor localization to synapse)|mint:Q8BIZ1|refseq:NP_001170868.1|refseq:NP_001170869.1|refseq:NP_001333982.1|refseq:NP_001333983.1|refseq:NP_852063.1|interpro:IPR033636|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|hgnc:"MGI:1924781"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:xm2OG9kb/tmIo7e7c/qXBE4JeAY10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q5SQX6	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-773783|uniprotkb:Q3UH21|uniprotkb:Q3UHS8|uniprotkb:Q8BSW0|uniprotkb:Q8CHA9|uniprotkb:Q924D3|uniprotkb:Q9R181|ensembl:ENSMUSP00000090853|ensembl:ENSMUSP00000090854|ensembl:ENSMUSP00000127586	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:cyfp2_mouse(display_long)|uniprotkb:p53-inducible protein 121(gene name synonym)|uniprotkb:Cyfip2(gene name)|psi-mi:Cyfip2(display_short)|uniprotkb:Kiaa1168(gene name synonym)|uniprotkb:Pir121(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_598530.2|refseq:NP_001239388.1|refseq:NP_001239389.1|dip:DIP-32111N|ensembl:ENSMUSG00000020340(gene)|ensembl:ENSMUST00000093165(transcript)|ensembl:ENSMUST00000093166(transcript)|ensembl:ENSMUST00000165599(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031209"(SCAR complex)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051388"(positive regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0097484"(dendrite extension)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR008081(Cytoplasmic FMR1-interacting)|interpro:IPR009828(Protein of unknown function DUF1394)|reactome:R-MMU-2029482|reactome:R-MMU-4420097|reactome:R-MMU-5663213|reactome:R-MMU-9013149|hgnc:"MGI:1924134"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:NP2S3AEcTj9DHTiDHEVM51b8jrE10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q925I1	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-772703|uniprotkb:Q3UE74|uniprotkb:Q69ZM7|uniprotkb:Q8C6C6|uniprotkb:A2AD89|uniprotkb:Q3TA78|ensembl:ENSMUSP00000030903	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:atad3_mouse(display_long)|uniprotkb:AAA-ATPase TOB3(gene name synonym)|uniprotkb:Atad3(gene name)|psi-mi:Atad3(display_short)|uniprotkb:Atad3a(gene name synonym)|uniprotkb:Kiaa1273(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_849534.2|dip:DIP-32373N|ensembl:ENSMUSG00000029036(gene)|ensembl:ENSMUST00000030903(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR021911|interpro:IPR027417|interpro:IPR039188|mint:Q925I1|reactome:R-MMU-6798695|hgnc:"MGI:1919214"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:ftt3s2Khsm5F0iodev1GLQFMHqg10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q9DBG3	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-775229|uniprotkb:Q80XJ4|ensembl:ENSMUSP00000070714	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:ap2b1_mouse(display_long)|uniprotkb:Beta-2-adaptin(gene name synonym)|uniprotkb:Beta-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin beta subunit(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 beta large chain(gene name synonym)|uniprotkb:AP105B(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit beta(gene name synonym)|uniprotkb:Ap2b1(gene name)|psi-mi:Ap2b1(display_short)|uniprotkb:Clapb1(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit beta(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001030931.1|refseq:NP_082191.1|refseq:XP_006534321.1|refseq:XP_017170261.1|dip:DIP-32161N|ensembl:ENSMUSG00000035152(gene)|ensembl:ENSMUST00000065692(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0003279"(cardiac septum development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007507"(heart development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030276"(clathrin binding)|go:"GO:0035904"(aorta development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099590"(neurotransmitter receptor internalization)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1905477"(positive regulation of protein localization to membrane)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013037(Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|mint:Q9DBG3|rcsb pdb:6OWO|rcsb pdb:6OXL|reactome:R-MMU-177504|reactome:R-MMU-2132295|reactome:R-MMU-416993|reactome:R-MMU-437239|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8866427|reactome:R-MMU-8964038|hgnc:"MGI:1919020"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:YWwOqRpXCJDwzrLv27muBx1+DHI10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q71LX4	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-2255655|uniprotkb:E9QM49|uniprotkb:Q8BWK0	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:tln2_mouse(display_long)|uniprotkb:Tln2(gene name)|psi-mi:Tln2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	mint:Q71LX4|refseq:NP_001074711.2|dip:DIP-53098N|go:"GO:0001726"(ruffle)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0045202"(synapse)|go:"GO:0051015"(actin filament binding)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR002558(I/LWEQ)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR015009(Vinculin Binding Site)|interpro:IPR015224(Talin, central)|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR032425|interpro:IPR035963|interpro:IPR035964|interpro:IPR036723|interpro:IPR037438|rcsb pdb:3G9W|interpro:IPR036476|hgnc:"MGI:1917799"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:fPA7JK3ca5p+y6dQlF+Srehsd2A10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q9EQZ6	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-772212|uniprotkb:Q8VIP9|uniprotkb:Q9CW52|uniprotkb:Q9Z1P0|ensembl:ENSMUSP00000088336	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:rpgf4_mouse(display_long)|uniprotkb:cAMP-regulated guanine nucleotide exchange factor II(gene name synonym)|uniprotkb:Exchange factor directly activated by cAMP 2(gene name synonym)|uniprotkb:Exchange protein directly activated by cAMP 2(gene name synonym)|uniprotkb:cAMP-dependent Rap1 guanine-nucleotide exchange factor(gene name synonym)|uniprotkb:Rapgef4(gene name)|psi-mi:Rapgef4(display_short)|uniprotkb:Cgef2(gene name synonym)|uniprotkb:Epac2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_062662.1|refseq:NP_001191094.1|refseq:NP_001191095.1|dip:DIP-32333N|ensembl:ENSMUSG00000049044(gene)|ensembl:ENSMUST00000090826(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005929"(cilium)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030073"(insulin secretion)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030552"(cAMP binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044316"(cone cell pedicle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0060076"(excitatory synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:1904457"(positive regulation of neuronal action potential)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018490|interpro:IPR019804|interpro:IPR023578|interpro:IPR029071|interpro:IPR036388|interpro:IPR036390|interpro:IPR036964|rcsb pdb:1O7F|rcsb pdb:2BYV|rcsb pdb:3CF6|rcsb pdb:4F7Z|rcsb pdb:4MGI|rcsb pdb:4MGK|rcsb pdb:4MGY|rcsb pdb:4MGZ|rcsb pdb:4MH0|reactome:R-MMU-354192|reactome:R-MMU-381676|reactome:R-MMU-392517|reactome:R-MMU-422356|hgnc:"MGI:1917723"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:E6oFNR3wXazvvq3wWWxfn4CW5F410090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q3UHC7	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-6306507|ensembl:ENSMUSP00000088532|uniprotkb:A2AUW9|uniprotkb:A2AUX2|uniprotkb:B7ZD28|uniprotkb:Q3TPD5|uniprotkb:Q3UH44|uniprotkb:Q6JTV1|uniprotkb:Q80T97|uniprotkb:A5X2X2|uniprotkb:Q6Y636	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:dab2p_mouse(display_long)|uniprotkb:ASK-interacting protein 1(gene name synonym)|uniprotkb:DOC-2/DAB-2 interactive protein(gene name synonym)|uniprotkb:Dab2ip(gene name)|psi-mi:Dab2ip(display_short)|uniprotkb:Kiaa1743(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000026883(gene)|ensembl:ENSMUST00000091010(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0001525"(angiogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005123"(death receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007049"(cell cycle)|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021814"(cell motility involved in cerebral cortex radial glia guided migration)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035148"(tube formation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0036324"(vascular endothelial growth factor receptor-2 signaling pathway)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043184"(vascular endothelial growth factor receptor 2 binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0043553"(negative regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044301"(climbing fiber)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070317"(negative regulation of G0 to G1 transition)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1903363"(negative regulation of cellular protein catabolic process)|go:"GO:1990032"(parallel fiber)|go:"GO:1990597"(AIP1-IRE1 complex)|go:"GO:2001224"(positive regulation of neuron migration)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR030403|interpro:IPR035892|interpro:IPR039360|reactome:R-MMU-5658442|interpro:IPR001849(Pleckstrin-like)|refseq:NP_001277568.1|refseq:NP_001277569.1|refseq:NP_001277570.1|refseq:NP_001001602.2|refseq:NP_001107596.1|refseq:NP_001107597.1|refseq:XP_006498370.2|hgnc:"MGI:1916851"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:2TdjnHyR0jQG+iT5S5+JaK8hhfY10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q8K2T1	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-9989325|uniprotkb:Q8BVF0|uniprotkb:Q9CZP2|ensembl:ENSMUSP00000078132	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:nmrl1_mouse(display_long)|uniprotkb:Nmral1(gene name)|psi-mi:Nmral1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001277690.1|refseq:NP_001277691.1|refseq:NP_001277692.1|refseq:NP_080669.1|ensembl:ENSMUSG00000063445(gene)|ensembl:ENSMUST00000079130(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR036291|reactome:R-MMU-70635|interpro:IPR008030(NmrA-like)|hgnc:"MGI:1915074"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:Nu/flWLp6q6bma0LicTfQmE1tMQ10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q5DTY9	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-6271974|ensembl:ENSMUSP00000089547|ensembl:ENSMUSP00000158201|uniprotkb:Q78Y50	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:kcd16_mouse(display_long)|uniprotkb:Kctd16(gene name)|psi-mi:Kctd16(display_short)|uniprotkb:Gm1267(gene name synonym)|uniprotkb:Kiaa1317(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000051401(gene)|ensembl:ENSMUST00000091927(transcript)|ensembl:ENSMUST00000236889(transcript)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042995"(cell projection)|go:"GO:0043235"(receptor complex)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR011333(BTB/POZ fold)|refseq:NP_080411.1|refseq:XP_017173425.1|refseq:XP_017173426.1|refseq:XP_017173427.1|refseq:XP_017173428.1|hgnc:"MGI:1914659"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:zwueT9a7iunyYziWGHoKiD8luq810090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P57780	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-445071|ensembl:ENSMUSP00000066068	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:actn4_mouse(display_long)|uniprotkb:Non-muscle alpha-actinin 4(gene name synonym)|uniprotkb:Actn4(gene name)|psi-mi:Actn4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_068695.1|go:"GO:1903506"(regulation of nucleic acid-templated transcription)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:P57780|reactome:R-MMU-114608|ensembl:ENSMUSG00000054808(gene)|ensembl:ENSMUST00000068045(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001725"(stress fiber)|go:"GO:0001882"(nucleoside binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030018"(Z disc)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031143"(pseudopodium)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048549"(positive regulation of pinocytosis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902396"(protein localization to bicellular tight junction)|hgnc:"MGI:1890773"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:IeHeXy0Cx5E6ivN3b8IxESBlhJI10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q8R5H6	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-774719|uniprotkb:Q91W51|uniprotkb:Q9ERQ9|ensembl:ENSMUSP00000019975|ensembl:ENSMUSP00000101148	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:wasf1_mouse(display_long)|uniprotkb:Protein WAVE-1(gene name synonym)|uniprotkb:Wasf1(gene name)|psi-mi:Wasf1(display_short)|uniprotkb:Wave1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_114083.1|refseq:XP_006512995.1|ensembl:ENSMUSG00000019831(gene)|ensembl:ENSMUST00000019975(transcript)|ensembl:ENSMUST00000105509(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031209"(SCAR complex)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051388"(positive regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:0097484"(dendrite extension)|go:"GO:0098794"(postsynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098939"(dendritic transport of mitochondrion)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR028288|mint:Q8R5H6|reactome:R-MMU-2029482|reactome:R-MMU-4420097|reactome:R-MMU-5663213|reactome:R-MMU-9013149|reactome:R-MMU-9013423|hgnc:"MGI:1890563"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:t+4F2ap7lNjE/AGuIwMhel4YknU10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q9WV60	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-400793|ensembl:ENSMUSP00000023507	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:gsk3b_mouse(display_long)|uniprotkb:Gsk3b(gene name)|psi-mi:Gsk3b(display_short)|uniprotkb:Serine/threonine-protein kinase GSK3B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_062801.1|dip:DIP-32446N|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006983"(ER overload response)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007165"(signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0007520"(myoblast fusion)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010822"(positive regulation of mitochondrion organization)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014043"(negative regulation of neuron maturation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0034452"(dynactin binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|go:"GO:2000738"(positive regulation of stem cell differentiation)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033573|interpro:IPR039192|mint:Q9WV60|rcsb pdb:4NU1|rcsb pdb:5AIR|rcsb pdb:6AE3|reactome:R-MMU-195253|reactome:R-MMU-196299|reactome:R-MMU-3371453|reactome:R-MMU-399956|reactome:R-MMU-4641262|reactome:R-MMU-5250924|reactome:R-MMU-5610785|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035733"(hepatic stellate cell activation)|go:"GO:0036016"(cellular response to interleukin-3)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043227"(membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044027"(hypermethylation of CpG island)|go:"GO:0044297"(cell body)|go:"GO:0045121"(membrane raft)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045887"(positive regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046849"(bone remodeling)|go:"GO:0048156"(tau protein binding)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071109"(superior temporal gyrus development)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090290"(positive regulation of osteoclast proliferation)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099159"(regulation of modification of postsynaptic structure)|go:"GO:0106027"(neuron projection organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0150101"(regulation of microtubule anchoring at centrosome)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1901030"(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901984"(negative regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1904339"(negative regulation of dopaminergic neuron differentiation)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904780"(negative regulation of protein localization to centrosome)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000171"(negative regulation of dendrite development)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|ensembl:ENSMUSG00000022812(gene)|ensembl:ENSMUST00000023507(transcript)|go:"GO:0000320"(re-entry into mitotic cell cycle)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|hgnc:"MGI:1861437"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:FKe0WkOBBYU0vIJLmcFNMJ+KVHA10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q91VJ5	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-11034994|uniprotkb:Q9QYY2|uniprotkb:Q9ER43|uniprotkb:Q80WW2|ensembl:ENSMUSP00000033497|ensembl:ENSMUSP00000111318|ensembl:ENSMUSP00000111319	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:pqbp1_mouse(display_long)|uniprotkb:Pqbp1(gene name)|psi-mi:Pqbp1(display_short)|uniprotkb:38 kDa nuclear protein containing a WW domain(gene name synonym)|uniprotkb:Npw38(gene name synonym)|uniprotkb:Polyglutamine tract-binding protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001239457.1|refseq:NP_001239458.1|refseq:NP_062351.2|refseq:XP_006527717.1|ensembl:ENSMUSG00000031157(gene)|ensembl:ENSMUST00000033497(transcript)|ensembl:ENSMUST00000115654(transcript)|ensembl:ENSMUST00000115655(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0031175"(neuron projection development)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0045087"(innate immune response)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0051607"(defense response to virus)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:0097546"(ciliary base)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|reactome:R-MMU-72163|hgnc:"MGI:1859638"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:2r711AL0dhSk3EonjfJMWoMdN1M10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P28660	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-771576|uniprotkb:Q3UPY6|uniprotkb:Q80TX0|uniprotkb:Q8CG49|uniprotkb:Q99KY0|ensembl:ENSMUSP00000028386	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:nckp1_mouse(display_long)|uniprotkb:p125Nap1(gene name synonym)|uniprotkb:Membrane-associated protein HEM-2(gene name synonym)|uniprotkb:Brain protein H19(gene name synonym)|uniprotkb:MH19(gene name synonym)|uniprotkb:Nckap1(gene name)|psi-mi:Nckap1(display_short)|uniprotkb:Hem2(gene name synonym)|uniprotkb:Kiaa0587(gene name synonym)|uniprotkb:Nap1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_058661.1|ensembl:ENSMUSG00000027002(gene)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001726"(ruffle)|go:"GO:0001756"(somitogenesis)|go:"GO:0001843"(neural tube closure)|go:"GO:0007354"(zygotic determination of anterior/posterior axis, embryo)|go:"GO:0007492"(endoderm development)|go:"GO:0008078"(mesodermal cell migration)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030903"(notochord development)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031209"(SCAR complex)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031941"(filamentous actin)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0045175"(basal protein localization)|go:"GO:0045176"(apical protein localization)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048340"(paraxial mesoderm morphogenesis)|go:"GO:0048570"(notochord morphogenesis)|go:"GO:0048617"(embryonic foregut morphogenesis)|ensembl:ENSMUST00000028386(transcript)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0098794"(postsynapse)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR019137|mint:P28660|reactome:R-MMU-2029482|reactome:R-MMU-4420097|reactome:R-MMU-5663213|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013423|hgnc:"MGI:1355333"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:NIygMTpuScC4fys7MrAWJD7Hd4M10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q9JLC8	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16750634|uniprotkb:Q3TUF2|uniprotkb:Q6A007|uniprotkb:Q8BQT3|uniprotkb:Q8C764|uniprotkb:Q8CAJ4	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:sacs_mouse(display_long)|uniprotkb:Sacs(gene name)|psi-mi:Sacs(display_short)|uniprotkb:Kiaa0730(gene name synonym)|uniprotkb:DnaJ homolog subfamily C member 29(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	go:"GO:0005737"(cytoplasm)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051087"(chaperone binding)|refseq:NP_766397.2|interpro:IPR036869|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR036890|interpro:IPR007842(HEPN)|interpro:IPR029071|hgnc:"MGI:1354724"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:OU1dmkv4MvhodB4zNYWjiih9nSg10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q3UVX5	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-8795045|ensembl:ENSMUSP00000114927	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:grm5_mouse(display_long)|uniprotkb:Grm5(gene name)|psi-mi:Grm5(display_short)|uniprotkb:Gprc1e(gene name synonym)|uniprotkb:Mglur5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	go:"GO:0001640"(adenylate cyclase inhibiting G protein-coupled glutamate receptor activity)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002029"(desensitization of G protein-coupled receptor signaling pathway)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006448"(regulation of translational elongation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0001639"(PLC activating G protein-coupled glutamate receptor activity)|go:"GO:0007612"(learning)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0031687"(A2A adenosine receptor binding)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0040013"(negative regulation of locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048170"(positive regulation of long-term neuronal synaptic plasticity)|go:"GO:0050808"(synapse organization)|go:"GO:0050890"(cognition)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:0097449"(astrocyte projection)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:0099530"(G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential)|go:"GO:0099553"(trans-synaptic signaling by endocannabinoid, modulating synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:1902938"(regulation of intracellular calcium activated chloride channel activity)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000162(GPCR, family 3, metabotropic glutamate receptor)|interpro:IPR000202(GPCR, family 3, metabotropic glutamate receptor 5)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR011500(GPCR, family 3, nine cysteines region)|interpro:IPR017978|interpro:IPR017979|interpro:IPR019588|interpro:IPR028082|interpro:IPR038550|reactome:R-MMU-416476|reactome:R-MMU-420499|reactome:R-MMU-6794361|go:"GO:0099583"(neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|ensembl:ENSMUSG00000049583(gene)|ensembl:ENSMUST00000155358(transcript)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|refseq:XP_011239945.1|refseq:NP_001137306.1|hgnc:"MGI:1351342"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:pA3IUBq9r3mGn7M8R2qnAaYqaT810090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q14BI2	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-5281533|ensembl:ENSMUSP00000023959	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:grm2_mouse(display_long)|uniprotkb:Grm2(gene name)|psi-mi:Grm2(display_short)|uniprotkb:Gprc1b(gene name synonym)|uniprotkb:Mglur2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001153825.1|ensembl:ENSMUSG00000023192(gene)|ensembl:ENSMUST00000023959(transcript)|go:"GO:0001640"(adenylate cyclase inhibiting G protein-coupled glutamate receptor activity)|go:"GO:0001641"(group II metabotropic glutamate receptor activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0010467"(gene expression)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014048"(regulation of glutamate secretion)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0042220"(response to cocaine)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0090461"(glutamate homeostasis)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:2001023"(regulation of response to drug)|interpro:IPR000162(GPCR, family 3, metabotropic glutamate receptor)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001458(GPCR, family 3, metabotropic glutamate receptor 2)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR011500(GPCR, family 3, nine cysteines region)|interpro:IPR017978|interpro:IPR017979|interpro:IPR028082|interpro:IPR038550|mint:Q14BI2|reactome:R-MMU-418594|reactome:R-MMU-420499|hgnc:"MGI:1351339"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:51Vq4ZsTylhat6thFK/8MBMIKUI10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:O08553	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-446064|uniprotkb:Q6P5D0|ensembl:ENSMUSP00000022629	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:dpyl2_mouse(display_long)|uniprotkb:Unc-33-like phosphoprotein 2(gene name synonym)|uniprotkb:Dpysl2(gene name)|psi-mi:Dpysl2(display_short)|uniprotkb:Crmp2(gene name synonym)|uniprotkb:Ulip2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_034085.2|ensembl:ENSMUSG00000022048(gene)|ensembl:ENSMUST00000022629(transcript)|go:"GO:0001975"(response to amphetamine)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0019901"(protein kinase binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043209"(myelin sheath)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0098793"(presynapse)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011778(D-hydantoinase)|interpro:IPR030615|interpro:IPR032466|mint:O08553|rcsb pdb:5UQC|reactome:R-MMU-399956|reactome:R-MMU-437239|hgnc:"MGI:1349763"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:97yc8TNEPMcGtGNRLvl+KV+DYr010090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q9QYX7	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-771361|uniprotkb:Q8CF91|uniprotkb:Q8CF92|uniprotkb:Q9QYX6|uniprotkb:Q9QZJ0|uniprotkb:E9QK94|ensembl:ENSMUSP00000030691	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:pclo_mouse(display_long)|uniprotkb:Aczonin(gene name synonym)|uniprotkb:Multidomain presynaptic cytomatrix protein(gene name synonym)|uniprotkb:Brain-derived HLMN protein(gene name synonym)|uniprotkb:Pclo(gene name)|psi-mi:Pclo(display_short)|uniprotkb:Acz(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001104266.1|refseq:NP_036125.4|ensembl:ENSMUSG00000061601(gene)|ensembl:ENSMUST00000030691(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030073"(insulin secretion)|go:"GO:0030133"(transport vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0044316"(cone cell pedicle)|go:"GO:0044317"(rod spherule)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0050808"(synapse organization)|go:"GO:0051036"(regulation of endosome size)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099526"(presynapse to nucleus signaling pathway)|go:"GO:1903423"(positive regulation of synaptic vesicle recycling)|go:"GO:1904071"(presynaptic active zone assembly)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008899(Zinc finger, piccolo-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR030629|interpro:IPR035892|interpro:IPR036034|interpro:IPR042720|mint:Q9QYX7|hgnc:"MGI:1349390"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:jxSIEqJ4Fq8vMZntI3qZRQLQoUQ10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q9Z0E0	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-775082|uniprotkb:Q3TCW4|uniprotkb:Q80TW1|uniprotkb:Q91YH7|uniprotkb:Q9CW81|uniprotkb:Q9QUQ0|ensembl:ENSMUSP00000030637|ensembl:ENSMUSP00000101722	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:ncdn_mouse(display_long)|uniprotkb:Sfap75(gene name synonym)|uniprotkb:Norbin(gene name synonym)|uniprotkb:M-Sema F-associating protein of 75 kDa(gene name synonym)|uniprotkb:Ncdn(gene name)|psi-mi:Ncdn(display_short)|uniprotkb:Kiaa0607(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_036116.3|refseq:XP_006503181.1|refseq:XP_006503182.1|ensembl:ENSMUSG00000028833(gene)|ensembl:ENSMUST00000030637(transcript)|ensembl:ENSMUST00000106116(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0045453"(bone resorption)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0098794"(postsynapse)|interpro:IPR008709(Neurochondrin)|interpro:IPR016024(Armadillo-type fold)|mint:Q9Z0E0|hgnc:"MGI:1347351"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:afzLC/h+kiexMllkeyxpn1btb1U10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P63085	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-397697|uniprotkb:P27703|uniprotkb:Q3V1U6|ensembl:ENSMUSP00000156154|ensembl:ENSMUSP00000065983|ensembl:ENSMUSP00000111396	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:mk01_mouse(display_long)|uniprotkb:Mapk1(gene name)|psi-mi:Mapk1(display_short)|uniprotkb:Erk2(gene name synonym)|uniprotkb:Mapk(gene name synonym)|uniprotkb:Prkm1(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 2(gene name synonym)|uniprotkb:MAP kinase isoform p42(gene name synonym)|uniprotkb:ERT1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001033752.1|refseq:NP_036079.1|refseq:XP_006522210.1|dip:DIP-661N|ensembl:ENSMUST00000069107(transcript)|ensembl:ENSMUST00000115731(transcript)|ensembl:ENSMUST00000232611(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015966"(diadenosine tetraphosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019858"(cytosine metabolic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030424"(axon)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035094"(response to nicotine)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043627"(response to estrogen)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046697"(decidualization)|go:"GO:0048538"(thymus development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P63085|reactome:R-MMU-111995|reactome:R-MMU-112409|reactome:R-MMU-112411|reactome:R-MMU-1295596|reactome:R-MMU-162658|reactome:R-MMU-170968|reactome:R-MMU-198753|reactome:R-MMU-202670|reactome:R-MMU-2029482|reactome:R-MMU-2559580|reactome:R-MMU-2559582|reactome:R-MMU-2559585|reactome:R-MMU-2871796|reactome:R-MMU-3371453|reactome:R-MMU-375165|reactome:R-MMU-437239|reactome:R-MMU-445144|reactome:R-MMU-450341|reactome:R-MMU-456926|reactome:R-MMU-5654726|reactome:R-MMU-5654727|reactome:R-MMU-5654732|reactome:R-MMU-5654733|reactome:R-MMU-5663213|reactome:R-MMU-5668599|reactome:R-MMU-5673001|reactome:R-MMU-5674135|reactome:R-MMU-5674499|reactome:R-MMU-5675221|reactome:R-MMU-6798695|reactome:R-MMU-6811558|reactome:R-MMU-74749|reactome:R-MMU-881907|reactome:R-MMU-8939211|reactome:R-MMU-9627069|reactome:R-MMU-9634635|ensembl:ENSMUSG00000063358(gene)|reactome:R-MMU-9634638|reactome:R-MMU-982772|hgnc:"MGI:1346858"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:4STZhl2O+Ilh0lj8wQp8y2vVehA10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q9QWY8	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-698498|uniprotkb:Q99LV8|uniprotkb:Q9Z2B6|uniprotkb:O08612|uniprotkb:Q80TG8|uniprotkb:Q80UV6|uniprotkb:Q505F0|ensembl:ENSMUSP00000134825	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:asap1_mouse(display_long)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:Asap1(gene name)|psi-mi:Asap1(display_short)|uniprotkb:Ddef1(gene name synonym)|uniprotkb:Kiaa1249(gene name synonym)|uniprotkb:Shag1(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001263396.1|refseq:NP_034156.2|refseq:NP_001263390.1|refseq:NP_001263391.1|ensembl:ENSMUSG00000022377(gene)|ensembl:ENSMUST00000177374(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002102"(podosome)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0031253"(cell projection membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:1903527"(positive regulation of membrane tubulation)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027267|interpro:IPR036028|interpro:IPR036770|interpro:IPR037278|interpro:IPR037844|interpro:IPR037928|interpro:IPR038016|interpro:IPR038508|interpro:IPR043593|mint:Q9QWY8|rcsb pdb:5C6R|rcsb pdb:5C79|reactome:R-MMU-5620916|hgnc:"MGI:1342335"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:/jhMt+/t+DTqI3ZQmzU0IMFCHdA10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q6PHZ2	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-2308458|uniprotkb:Q3UF87|uniprotkb:Q3UQH9|uniprotkb:Q5DTK4|uniprotkb:Q8CAC5|uniprotkb:Q9CZE2|ensembl:ENSMUSP00000143504	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:kcc2d_mouse(display_long)|uniprotkb:Camk2d(gene name)|psi-mi:Camk2d(display_short)|uniprotkb:Kiaa4163(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001020609.1|refseq:NP_076302.1|refseq:NP_001020610.1|refseq:NP_001280592.1|refseq:NP_001280593.1|dip:DIP-47638N|ensembl:ENSMUSG00000053819(gene)|ensembl:ENSMUST00000199300(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0014704"(intercalated disc)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0031432"(titin binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043194"(axon initial segment)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0098901"(regulation of cardiac muscle cell action potential)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901897"(regulation of relaxation of cardiac muscle)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:1902514"(regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|mint:Q6PHZ2|rcsb pdb:6BAB|reactome:R-MMU-3371571|reactome:R-MMU-399719|reactome:R-MMU-438066|reactome:R-MMU-5576892|reactome:R-MMU-5578775|reactome:R-MMU-5673000|reactome:R-MMU-5673001|reactome:R-MMU-877300|reactome:R-MMU-936837|hgnc:"MGI:1341265"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:z2mz73Kq9gwpKgo2Todn0IxQpSI10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:O55106	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-2479958|uniprotkb:B2RWV9|uniprotkb:Q5BKR9|ensembl:ENSMUSP00000120830	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:strn_mouse(display_long)|uniprotkb:Strn(gene name)|psi-mi:Strn(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000024077(gene)|ensembl:ENSMUST00000145910(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016358"(dendrite development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030425"(dendrite)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR013258(Striatin, N-terminal)|go:"GO:0014069"(postsynaptic density)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O55106|reactome:R-MMU-1257604|reactome:R-MMU-6811558|reactome:R-MMU-9009391|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_035630.2|hgnc:"MGI:1333757"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:tUJDyyIWZKuEBcyJKUIbk2dR4JE10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q9JLM8	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-771719|uniprotkb:Q6P207|ensembl:ENSMUSP00000050034	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:dclk1_mouse(display_long)|uniprotkb:Doublecortin-like and CAM kinase-like 1(gene name synonym)|uniprotkb:Dclk1(gene name)|psi-mi:Dclk1(display_short)|uniprotkb:Dclk(gene name synonym)|uniprotkb:Dcamkl1(gene name synonym)|uniprotkb:Doublecortin-like kinase 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_064362.1|ensembl:ENSMUSG00000027797(gene)|ensembl:ENSMUST00000054237(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0009615"(response to virus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0030900"(forebrain development)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048675"(axon extension)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003533(Doublecortin)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036572|mint:Q9JLM8|hgnc:"MGI:1330861"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:P3ZZ2GyKcdMimAcekZ8OlLbuciM10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P97350	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-4280963|uniprotkb:B2RSX3|ensembl:ENSMUSP00000027667|ensembl:ENSMUSP00000128418	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:pkp1_mouse(display_long)|uniprotkb:Pkp1(gene name)|psi-mi:Pkp1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001300630.1|ensembl:ENSMUSG00000026413(gene)|ensembl:ENSMUST00000027667(transcript)|ensembl:ENSMUST00000163260(transcript)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030057"(desmosome)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0045296"(cadherin binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1902373"(negative regulation of mRNA catabolic process)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028432|interpro:IPR028435|mint:P97350|reactome:R-MMU-351906|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|refseq:NP_062619.1|hgnc:"MGI:1328359"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:0u1sErZ6PA3jKsFg7DQ9NlLMevI10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q9QYR6	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-774021|uniprotkb:A2ARN9|uniprotkb:Q3TQM8|uniprotkb:Q3TUV8|uniprotkb:Q3UHB7|uniprotkb:Q9QZH9|uniprotkb:Q9QZI0|uniprotkb:Q9QZI1|ensembl:ENSMUSP00000106269	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:map1a_mouse(display_long)|uniprotkb:Map1a(gene name)|psi-mi:Map1a(display_short)|uniprotkb:Mtap1(gene name synonym)|uniprotkb:Mtap1a(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001166977.1|refseq:NP_115769.1|ensembl:ENSMUSG00000027254(gene)|ensembl:ENSMUST00000110639(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003779"(actin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007613"(memory)|go:"GO:0008017"(microtubule binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008306"(associative learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016358"(dendrite development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031114"(regulation of microtubule depolymerization)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043194"(axon initial segment)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044307"(dendritic branch)|go:"GO:0045202"(synapse)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:0099642"(retrograde axonal protein transport)|go:"GO:0150001"(primary dendrite)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1902817"(negative regulation of protein localization to microtubule)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990535"(neuron projection maintenance)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR015656(MAP1A)|interpro:IPR026074|interpro:IPR036866|mint:Q9QYR6|rcsb pdb:5GNV|hgnc:"MGI:1306776"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:YFVfrv4h8ioQ9vL1A9LYsA5xriQ10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q7TSJ2	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-774081|uniprotkb:O55129|uniprotkb:O70586|uniprotkb:O70587|uniprotkb:Q78DV4|uniprotkb:Q78DV5|intact:EBI-911047|ensembl:ENSMUSP00000064787|ensembl:ENSMUSP00000146585	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:map6_mouse(display_long)|uniprotkb:Map6(gene name)|psi-mi:Map6(display_short)|uniprotkb:Mtap6(gene name synonym)|uniprotkb:Stable tubule-only polypeptide(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001036820.2|refseq:NP_001041632.1|refseq:NP_034967.2|ensembl:ENSMUSG00000055407(gene)|ensembl:ENSMUST00000068973(transcript)|ensembl:ENSMUST00000207883(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032418"(lysosome localization)|go:"GO:0043005"(neuron projection)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0099503"(secretory vesicle)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR007882(STOP)|mint:Q7TSJ2|hgnc:"MGI:1201690"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:NfrleOOHFaMul1xiYAgILTgLzWg10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q571I4	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-2642562|uniprotkb:Q8CB68|ensembl:ENSMUSP00000106118|uniprotkb:E9QLH9	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:prag1_mouse(display_long)|uniprotkb:D8Ertd82e(gene name synonym)|uniprotkb:Nack(gene name synonym)|uniprotkb:Notch activation complex kinase(gene name synonym)|uniprotkb:Prag1(gene name)|psi-mi:Prag1(display_short)|uniprotkb:Sgk223(gene name synonym)|uniprotkb:Sugen kinase 223(gene name synonym)|uniprotkb:Tyrosine-protein kinase SgK223(gene name synonym)|uniprotkb:PEAK1-related kinase-activating pseudokinase 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_766499.2|refseq:XP_011240439.1|ensembl:ENSMUSG00000050271(gene)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008266(Tyrosine protein kinase, active site)|ensembl:ENSMUST00000110492(transcript)|interpro:IPR011009(Protein kinase-like)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016477"(cell migration)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:2000145"(regulation of cell motility)|hgnc:"MGI:1196223"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:YHeN6FfRpyIpxIHxiLzjjINANbw10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q8BUV3	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-771218|uniprotkb:E9QKJ1|ensembl:ENSMUSP00000054064	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:geph_mouse(display_long)|uniprotkb:Gphn(gene name)|psi-mi:Gphn(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_766540.2|ensembl:ENSMUSG00000047454(gene)|ensembl:ENSMUST00000052472(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006777"(Mo-molybdopterin cofactor biosynthetic process)|go:"GO:0007529"(establishment of synaptic specificity at neuromuscular junction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008940"(nitrate reductase activity)|go:"GO:0010038"(response to metal ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018315"(molybdenum incorporation into molybdenum-molybdopterin complex)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032324"(molybdopterin cofactor biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043546"(molybdopterin cofactor binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061598"(molybdopterin adenylyltransferase activity)|go:"GO:0061599"(molybdopterin molybdotransferase activity)|go:"GO:0072579"(glycine receptor clustering)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097112"(gamma-aminobutyric acid receptor clustering)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098879"(structural constituent of postsynaptic specialization)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|go:"GO:0099144"(anchored component of synaptic membrane)|go:"GO:0099572"(postsynaptic specialization)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|interpro:IPR001453(Molybdopterin binding)|interpro:IPR005110(MoeA, N-terminal, domain I and II)|interpro:IPR005111(MoeA, C-terminal, domain IV)|interpro:IPR008284(Molybdenum cofactor biosynthesis, conserved site)|interpro:IPR036135|interpro:IPR036425|interpro:IPR036688|interpro:IPR038987|mint:Q8BUV3|reactome:R-MMU-947581|hgnc:"MGI:109602"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:lOuhzjy/8/eDNnV08I0WbLvRiiA10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q8BWW9	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-16750575|uniprotkb:Q3TBR3|uniprotkb:Q80WS2|uniprotkb:Q8BJL7|uniprotkb:Q8BL62|ensembl:ENSMUSP00000039566	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:pkn2_mouse(display_long)|uniprotkb:Pkn2(gene name)|psi-mi:Pkn2(display_short)|uniprotkb:Prk2(gene name synonym)|uniprotkb:Prkcl2(gene name synonym)|uniprotkb:PKN gamma(gene name synonym)|uniprotkb:Protein kinase C-like 2(gene name synonym)|uniprotkb:Protein-kinase C-related kinase 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_848769.2|ensembl:ENSMUSG00000004591(gene)|ensembl:ENSMUST00000043812(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0010631"(epithelial cell migration)|go:"GO:0016301"(kinase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0043297"(apical junction assembly)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR035892|interpro:IPR036274|interpro:IPR037313|interpro:IPR037784|reactome:R-MMU-5625740|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013149|hgnc:"MGI:109211"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:410k87bdX5FT5IoFc8oKbq2Z0LQ10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q9QXZ0	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-643248|intact:EBI-2658096|uniprotkb:B1ARU3|uniprotkb:Q4PLL5|uniprotkb:P97394|uniprotkb:P97395|uniprotkb:P97396	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:macf1_mouse(display_long)|uniprotkb:Actin cross-linking family 7(gene name synonym)|uniprotkb:Macf1(gene name)|psi-mi:Macf1(display_short)|uniprotkb:Acf7(gene name synonym)|uniprotkb:Aclp7(gene name synonym)|uniprotkb:Macf(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR002017(Spectrin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR001101(Plectin repeat)|interpro:IPR018159|interpro:IPR001452(Src homology-3)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0032587"(ruffle membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008017"(microtubule binding)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0042060"(wound healing)|go:"GO:0008104"(protein localization)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0150011"(regulation of neuron projection arborization)|mint:Q9QXZ0|interpro:IPR035915|interpro:IPR036534|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|hgnc:"MGI:108559"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:niJxpkI45VTa5x73A1tuX/aLXgo10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q03173	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-6083294|uniprotkb:P70430|uniprotkb:P70431|uniprotkb:P70432|uniprotkb:P70433|uniprotkb:Q5D053	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:enah_mouse(display_long)|uniprotkb:Enah(gene name)|psi-mi:Enah(display_short)|uniprotkb:Mena(gene name synonym)|uniprotkb:Ndpp1(gene name synonym)|uniprotkb:NPC-derived proline-rich protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	mint:Q03173|refseq:NP_001076590.1|dip:DIP-29359N|go:"GO:0001725"(stress fiber)|go:"GO:0001843"(neural tube closure)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007411"(axon guidance)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030175"(filopodium)|go:"GO:0045202"(synapse)|go:"GO:0050699"(WW domain binding)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR038023|rcsb pdb:1EVH|rcsb pdb:4CC3|reactome:R-MMU-376176|hgnc:"MGI:108360"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:MLNC5NL3QIW9Y/aUkc9dTNNAedM10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P97300	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-774154|uniprotkb:Q3U519|uniprotkb:Q8C637|uniprotkb:Q8C6H8|ensembl:ENSMUSP00000135199	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:nptn_mouse(display_long)|uniprotkb:Stromal cell-derived receptor 1(gene name synonym)|uniprotkb:Nptn(gene name)|psi-mi:Nptn(display_short)|uniprotkb:Sdfr1(gene name synonym)|uniprotkb:Sdr1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001280602.1|refseq:NP_033171.2|refseq:XP_006510945.1|refseq:XP_006510946.1|ensembl:ENSMUSG00000032336(gene)|ensembl:ENSMUST00000177292(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005105"(type 1 fibroblast growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007411"(axon guidance)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0045743"(positive regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0048170"(positive regulation of long-term neuronal synaptic plasticity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050808"(synapse organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099557"(trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1902683"(regulation of receptor localization to synapse)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1904861"(excitatory synapse assembly)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR027112|interpro:IPR036179|interpro:IPR043204|mint:P97300|go:"GO:0044325"(transmembrane transporter binding)|hgnc:"MGI:108077"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:t0jdeaic1GtKiVLSbZatothsVQg10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P97427	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-773110|uniprotkb:O08554|uniprotkb:O35097|ensembl:ENSMUSP00000031004	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:dpyl1_mouse(display_long)|uniprotkb:Collapsin response mediator protein 1(gene name synonym)|uniprotkb:Unc-33-like phosphoprotein 3(gene name synonym)|uniprotkb:Crmp1(gene name)|psi-mi:Crmp1(display_short)|uniprotkb:Dpysl1(gene name synonym)|uniprotkb:Ulip3(gene name synonym)|uniprotkb:Inactive dihydropyrimidinase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_031791.3|ensembl:ENSMUSG00000029121(gene)|ensembl:ENSMUST00000031004(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007411"(axon guidance)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031005"(filamin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:1904530"(negative regulation of actin filament binding)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011778(D-hydantoinase)|interpro:IPR030624|interpro:IPR032466|mint:P97427|rcsb pdb:1KCX|reactome:R-MMU-399956|hgnc:"MGI:107793"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:/fpPxm3SNtnLKjXWrWOuG0QO3Nk10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P39053	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-397785|ensembl:ENSMUSP00000122679|uniprotkb:A2AN50|uniprotkb:A2AN51|uniprotkb:A2AN54|uniprotkb:A2AN55|uniprotkb:Q3UNM1|uniprotkb:Q5DTN7|uniprotkb:Q61358|uniprotkb:Q61359|uniprotkb:Q61360|uniprotkb:Q6PDM5|uniprotkb:Q8JZZ4|uniprotkb:Q9CSY7|uniprotkb:Q9QXX1	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:dyn1_mouse(display_long)|uniprotkb:Dnm1(gene name)|psi-mi:Dnm1(display_short)|uniprotkb:Dnm(gene name synonym)|uniprotkb:Kiaa4093(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_034195.2|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR027741|interpro:IPR030381|mint:P39053|reactome:R-MMU-166016|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2132295|reactome:R-MMU-437239|reactome:R-MMU-8856828|ensembl:ENSMUSG00000026825(gene)|ensembl:ENSMUST00000139624(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007032"(endosome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030424"(axon)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043196"(varicosity)|go:"GO:0043209"(myelin sheath)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0061025"(membrane fusion)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1901998"(toxin transport)|go:"GO:1903423"(positive regulation of synaptic vesicle recycling)|go:"GO:1904645"(response to amyloid-beta)|refseq:NP_001288666.1|refseq:XP_006497721.2|refseq:XP_006497722.2|refseq:XP_006497723.2|refseq:XP_006497724.2|refseq:XP_006497718.2|refseq:XP_017170817.1|hgnc:"MGI:107384"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:wtPz3gwyxU6tAgh5091LQpt099I10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:O08599	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-445322|uniprotkb:A2ARS2|uniprotkb:A2ARS3|uniprotkb:A2ARS4|uniprotkb:Q5WAC6|uniprotkb:Q8VD51|ensembl:ENSMUSP00000052440	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:stxb1_mouse(display_long)|uniprotkb:Protein unc-18 homolog 1(gene name synonym)|uniprotkb:Protein unc-18 homolog A(gene name synonym)|uniprotkb:Stxbp1(gene name)|psi-mi:Stxbp1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001107041.1|refseq:NP_033321.2|interpro:IPR043127|interpro:IPR043154|mint:O08599|go:"GO:0098794"(postsynapse)|go:"GO:0098891"(extrinsic component of presynaptic active zone membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099525"(presynaptic dense core vesicle exocytosis)|reactome:R-MMU-181429|reactome:R-MMU-181430|go:"GO:0106022"(positive regulation of vesicle docking)|go:"GO:1903296"(positive regulation of glutamate secretion, neurotransmission)|go:"GO:2000367"(regulation of acrosomal vesicle exocytosis)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|reactome:R-MMU-210500|reactome:R-MMU-212676|reactome:R-MMU-264642|reactome:R-MMU-888590|ensembl:ENSMUSG00000026797(gene)|ensembl:ENSMUST00000050000(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0002576"(platelet degranulation)|go:"GO:0003006"(developmental process involved in reproduction)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007412"(axon target recognition)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030424"(axon)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031338"(regulation of vesicle fusion)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032229"(negative regulation of synaptic transmission, GABAergic)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043306"(positive regulation of mast cell degranulation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050821"(protein stabilization)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098793"(presynapse)|dip:DIP-31951N|hgnc:"MGI:107363"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:yUYi89hDkfMdQ1BdH52swZQFCLk10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P63328	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-397208|uniprotkb:P12816|uniprotkb:P20652|uniprotkb:Q3UCU1|uniprotkb:Q64135|ensembl:ENSMUSP00000053101	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:pp2ba_mouse(display_long)|uniprotkb:Ppp3ca(gene name)|psi-mi:Ppp3ca(display_short)|uniprotkb:Calna(gene name synonym)|uniprotkb:Calmodulin-dependent calcineurin A subunit alpha isoform(gene name synonym)|uniprotkb:CAM-PRP catalytic subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_032939.1|refseq:NP_001280551.1|ensembl:ENSMUSG00000028161(gene)|ensembl:ENSMUST00000056758(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004723"(calcium-dependent protein serine/threonine phosphatase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016311"(dephosphorylation)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0097720"(calcineurin-mediated signaling)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0030018"(Z disc)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0033173"(calcineurin-NFAT signaling cascade)|go:"GO:0033192"(calmodulin-dependent protein phosphatase activity)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0036057"(slit diaphragm)|go:"GO:0042383"(sarcolemma)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1903244"(positive regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1905205"(positive regulation of connective tissue replacement)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR041751|interpro:IPR043360|mint:P63328|rcsb pdb:4ORB|reactome:R-MMU-2025928|reactome:R-MMU-2871809|reactome:R-MMU-4086398|reactome:R-MMU-5607763|dip:DIP-31543N|hgnc:"MGI:107164"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:98yAyDGZZxKYOv22ejceyfJbvao10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P48453	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-642618|uniprotkb:Q6NZR4|ensembl:ENSMUSP00000125722	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:pp2bb_mouse(display_long)|uniprotkb:Calmodulin-dependent calcineurin A subunit beta isoform(gene name synonym)|uniprotkb:CAM-PRP catalytic subunit(gene name synonym)|uniprotkb:Ppp3cb(gene name)|psi-mi:Ppp3cb(display_short)|uniprotkb:Calnb(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_032940.1|refseq:NP_001297355.1|refseq:NP_001297356.1|ensembl:ENSMUSG00000021816(gene)|ensembl:ENSMUST00000159027(transcript)|go:"GO:0001915"(negative regulation of T cell mediated cytotoxicity)|go:"GO:0001946"(lymphangiogenesis)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004723"(calcium-dependent protein serine/threonine phosphatase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007507"(heart development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0031987"(locomotion involved in locomotory behavior)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033173"(calcineurin-NFAT signaling cascade)|go:"GO:0033192"(calmodulin-dependent protein phosphatase activity)|go:"GO:0034097"(response to cytokine)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0097720"(calcineurin-mediated signaling)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR041751|interpro:IPR043360|mint:P48453|reactome:R-MMU-2025928|reactome:R-MMU-2871809|reactome:R-MMU-4086398|reactome:R-MMU-5607763|go:"GO:0005516"(calmodulin binding)|hgnc:"MGI:107163"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:YD7q3dcL87htgwHRd5m5ReMlqd010090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q61290	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-770918	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:cac1e_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.3(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 6(gene name synonym)|uniprotkb:Brain calcium channel II(gene name synonym)|uniprotkb:Cacna1e(gene name)|psi-mi:Cacna1e(display_short)|uniprotkb:Cach6(gene name synonym)|uniprotkb:Cacnl1a6(gene name synonym)|uniprotkb:Cchra1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR005449(Voltage-dependent calcium channel, R-type, alpha-1 subunit)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR027359|interpro:IPR031649|go:"GO:0001662"(behavioral fear response)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0042596"(fear response)|go:"GO:0043204"(perikaryon)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048265"(response to pain)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0050877"(nervous system process)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0090273"(regulation of somatostatin secretion)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099626"(voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels)|reactome:R-MMU-112308|reactome:R-MMU-422356|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042593"(glucose homeostasis)|mint:Q61290|hgnc:"MGI:106217"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:EaL/xQzdjloSLb88yMW1gqddCjM10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P60766	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-81763|ensembl:ENSMUSP00000054634|uniprotkb:A2A9U6|uniprotkb:P21181|uniprotkb:P25763|uniprotkb:Q3THZ7|uniprotkb:Q3TJK6|uniprotkb:Q545V0|uniprotkb:Q6P201|uniprotkb:Q8BQ51	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:cdc42_mouse(display_long)|uniprotkb:Cdc42(gene name)|psi-mi:Cdc42(display_short)|uniprotkb:G25K GTP-binding protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000006699(gene)|ensembl:ENSMUST00000051477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000322"(storage vacuole)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007015"(actin filament organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|refseq:NP_033991.1|go:"GO:0007097"(nuclear migration)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0016477"(cell migration)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030141"(secretory granule)|go:"GO:0030175"(filopodium)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030496"(midbody)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032427"(GBD domain binding)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0034191"(apolipoprotein A-I receptor binding)|go:"GO:0034329"(cell junction assembly)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0036336"(dendritic cell migration)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0038189"(neuropilin signaling pathway)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0043209"(myelin sheath)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045177"(apical part of cell)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048549"(positive regulation of pinocytosis)|go:"GO:0051233"(spindle midzone)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051647"(nucleus localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051835"(positive regulation of synapse structural plasticity)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0060047"(heart contraction)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060661"(submandibular salivary gland formation)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071944"(cell periphery)|go:"GO:0072384"(organelle transport along microtubule)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090135"(actin filament branching)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099159"(regulation of modification of postsynaptic structure)|go:"GO:0099563"(modification of synaptic structure)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|mint:P60766|rcsb pdb:3EG5|rcsb pdb:5C2J|reactome:R-MMU-114604|reactome:R-MMU-182971|reactome:R-MMU-2029482|reactome:R-MMU-389359|reactome:R-MMU-3928662|reactome:R-MMU-418885|reactome:R-MMU-4420097|reactome:R-MMU-525793|reactome:R-MMU-5625970|reactome:R-MMU-5626467|reactome:R-MMU-5627123|reactome:R-MMU-5663213|reactome:R-MMU-5663220|reactome:R-MMU-5687128|reactome:R-MMU-8964616|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013406|reactome:R-MMU-9013408|reactome:R-MMU-9013420|reactome:R-MMU-9013423|reactome:R-MMU-9013424|reactome:R-MMU-983231|go:"GO:0048664"(neuron fate determination)|refseq:NP_001230698.1|dip:DIP-32554N|hgnc:"MGI:106211"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:jiYEHWm+9LQyVj0eUGZOBGaajyU10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q99104	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-400199|uniprotkb:E9PUE5|ensembl:ENSMUSP00000116028	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:myo5a_mouse(display_long)|uniprotkb:Myo5a(gene name)|psi-mi:Myo5a(display_short)|uniprotkb:Dilute(gene name synonym)|uniprotkb:Dilute myosin heavy chain, non-muscle(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_034994.2|ensembl:ENSMUSG00000034593(gene)|ensembl:ENSMUST00000123128(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000149"(SNARE binding)|go:"GO:0001726"(ruffle)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006582"(melanin metabolic process)|go:"GO:0006887"(exocytosis)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0007015"(actin filament organization)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007601"(visual perception)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014046"(dopamine secretion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016459"(myosin complex)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030073"(insulin secretion)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031585"(regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0031982"(vesicle)|go:"GO:0031987"(locomotion involved in locomotory behavior)|go:"GO:0032252"(secretory granule localization)|go:"GO:0032400"(melanosome localization)|go:"GO:0032402"(melanosome transport)|go:"GO:0032433"(filopodium tip)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042438"(melanin biosynthetic process)|go:"GO:0042470"(melanosome)|go:"GO:0042476"(odontogenesis)|go:"GO:0042552"(myelination)|go:"GO:0042641"(actomyosin)|go:"GO:0042642"(actomyosin, myosin complex part)|go:"GO:0042759"(long-chain fatty acid biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043473"(pigmentation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0050808"(synapse organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099089"(establishment of endoplasmic reticulum localization to postsynapse)|go:"GO:0099566"(regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:0099640"(axo-dendritic protein transport)|go:"GO:0150103"(reactive gliosis)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1904960"(positive regulation of cytochrome-c oxidase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|go:"GO:0030318"(melanocyte differentiation)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR027417|interpro:IPR036103|interpro:IPR037988|mint:Q99104|rcsb pdb:2IX7|rcsb pdb:3WB8|rcsb pdb:4KP3|rcsb pdb:4ZLK|rcsb pdb:6KU0|reactome:R-MMU-2029482|interpro:IPR002710(Dilute)|go:"GO:0030141"(secretory granule)|dip:DIP-29542N|hgnc:"MGI:105976"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:8QtBlLL4DqB3An4CoCFVmvBEXBg10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P54285	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-770995|uniprotkb:G5E821|ensembl:ENSMUSP00000155514	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:cacb3_mouse(display_long)|uniprotkb:Calcium channel voltage-dependent subunit beta 3(gene name synonym)|uniprotkb:Cacnb3(gene name)|psi-mi:Cacnb3(display_short)|uniprotkb:Cacnlb3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_031607.2|ensembl:ENSMUSG00000003352(gene)|ensembl:ENSMUST00000230490(transcript)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0045202"(synapse)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:0098903"(regulation of membrane repolarization during action potential)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1901386"(negative regulation of voltage-gated calcium channel activity)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1901843"(positive regulation of high voltage-gated calcium channel activity)|go:"GO:1902630"(regulation of membrane hyperpolarization)|go:"GO:1905788"(negative regulation of detection of mechanical stimulus involved in sensory perception of touch)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|interpro:IPR001452(Src homology-3)|interpro:IPR008079(Voltage-dependent calcium channel, L-type, beta-3 subunit)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR035760|interpro:IPR036028|reactome:R-MMU-112308|reactome:R-MMU-422356|hgnc:"MGI:103307"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:LMu4stgWoR/M2O+zARtbshs2Ptc10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q9JHU4	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-645061|uniprotkb:E9QM71|ensembl:ENSMUSP00000018851	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:dyhc1_mouse(display_long)|uniprotkb:Dhc1(gene name synonym)|uniprotkb:Dyhc(gene name synonym)|uniprotkb:Cytoplasmic dynein heavy chain 1(gene name synonym)|uniprotkb:Dynein heavy chain, cytosolic(gene name synonym)|uniprotkb:Dync1h1(gene name)|psi-mi:Dync1h1(display_short)|uniprotkb:Dnch1(gene name synonym)|uniprotkb:Dnchc1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_084514.2|ensembl:ENSMUSG00000018707(gene)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002177"(manchette)|go:"GO:0003341"(cilium movement)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007097"(nuclear migration)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008569"(minus-end-directed microtubule motor activity)|go:"GO:0030175"(filopodium)|go:"GO:0030286"(dynein complex)|go:"GO:0030424"(axon)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051301"(cell division)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072382"(minus-end-directed vesicle transport along microtubule)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004273(Dynein heavy chain)|interpro:IPR013594(Dynein heavy chain, N-terminal region 1)|interpro:IPR013602(Dynein heavy chain, N-terminal region 2)|interpro:IPR024317|interpro:IPR024743|interpro:IPR027417|interpro:IPR035699|interpro:IPR035706|interpro:IPR041228|interpro:IPR041466|interpro:IPR041658|ensembl:ENSMUST00000018851(transcript)|interpro:IPR042222|interpro:IPR042228|interpro:IPR043157|interpro:IPR043160|interpro:IPR042219|mint:Q9JHU4|rcsb pdb:3ERR|rcsb pdb:3J1T|rcsb pdb:3J1U|rcsb pdb:3WUQ|rcsb pdb:5AYH|rcsb pdb:6RZA|rcsb pdb:6RZB|reactome:R-MMU-141444|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-6798695|reactome:R-MMU-6807878|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9646399|reactome:R-MMU-9648025|hgnc:"MGI:103147"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:sbED0xqQpe32T7I8ijeS3Xqlx7010090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q9Z2H5	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-774482|uniprotkb:Q3U3L1|uniprotkb:Q3UHP7|uniprotkb:Q80U34|uniprotkb:Q8K204	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:e41l1_mouse(display_long)|uniprotkb:Neuronal protein 4.1(gene name synonym)|uniprotkb:Epb41l1(gene name)|psi-mi:Epb41l1(display_short)|uniprotkb:Epb4(gene name synonym)|uniprotkb:Epb4.1l1(gene name synonym)|uniprotkb:Kiaa0338(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 4.1-like 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001278049.1|refseq:NP_001278051.1|refseq:NP_001278052.1|refseq:NP_001006665.1|refseq:NP_038538.1|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR019749|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019747|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR018979|interpro:IPR018980|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR007477(SAB)|interpro:IPR029071|interpro:IPR035963|mint:Q9Z2H5|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0097060"(synaptic membrane)|reactome:R-MMU-399719|reactome:R-MMU-6794361|hgnc:"MGI:103010"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:Lu31NnWhI356njHUtKbBlaO6nWE10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:Q9WV92	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-911885|uniprotkb:Q69ZT8|ensembl:ENSMUSP00000079098|uniprotkb:Q9R102	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:e41l3_mouse(display_long)|uniprotkb:4.1B(gene name synonym)|uniprotkb:Differentially expressed in adenocarcinoma of the lung protein 1(gene name synonym)|uniprotkb:Epb41l3(gene name)|psi-mi:Epb41l3(display_short)|uniprotkb:Dal1(gene name synonym)|uniprotkb:Epb4.1l3(gene name synonym)|uniprotkb:Kiaa0987(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 4.1-like 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000024044(gene)|ensembl:ENSMUST00000080208(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0002175"(protein localization to paranode region of axon)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030054"(cell junction)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030913"(paranodal junction assembly)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0033270"(paranode region of axon)|go:"GO:0043217"(myelin maintenance)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0071205"(protein localization to juxtaparanode region of axon)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0106006"(cytoskeletal protein-membrane anchor activity)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR007477(SAB)|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030691|interpro:IPR035963|mint:Q9WV92|reactome:R-MMU-6794361|refseq:NP_038841.1|refseq:XP_011244586.1|refseq:XP_011244591.1|refseq:XP_017172724.1|refseq:XP_017172725.1|hgnc:"MGI:103008"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:51gkxiswTUqQbAUqjGoPthWD7jM10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P17426	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-775189|ensembl:ENSMUSP00000082519|ensembl:ENSMUSP00000127842	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:ap2a1_mouse(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-1(gene name synonym)|uniprotkb:Alpha1-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit(gene name synonym)|uniprotkb:Alpha-adaptin A(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-A large chain(gene name synonym)|uniprotkb:100 kDa coated vesicle protein A(gene name synonym)|uniprotkb:Ap2a1(gene name)|psi-mi:Ap2a1(display_short)|uniprotkb:Adtaa(gene name synonym)|uniprotkb:Clapa1(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001070732.1|refseq:NP_031484.1|ensembl:ENSMUSG00000060279(gene)|ensembl:ENSMUST00000085399(transcript)|ensembl:ENSMUST00000166972(transcript)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0032433"(filopodium tip)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|mint:P17426|reactome:R-MMU-177504|reactome:R-MMU-2132295|reactome:R-MMU-416993|reactome:R-MMU-437239|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8866427|reactome:R-MMU-8964038|hgnc:"MGI:101921"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:Dd6Q+Et/LTlmo5qpro2Zaeq0dMc10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P17427	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-775215|uniprotkb:Q8C2J5|uniprotkb:Q921V0|ensembl:ENSMUSP00000003038	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:ap2a2_mouse(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-2(gene name synonym)|uniprotkb:Alpha2-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit(gene name synonym)|uniprotkb:Alpha-adaptin C(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-C large chain(gene name synonym)|uniprotkb:100 kDa coated vesicle protein C(gene name synonym)|uniprotkb:Ap2a2(gene name)|psi-mi:Ap2a2(display_short)|uniprotkb:Adtab(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_031485.3|dip:DIP-32160N|ensembl:ENSMUSG00000002957(gene)|ensembl:ENSMUST00000003038(transcript)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030141"(secretory granule)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|mint:P17427|rcsb pdb:1B9K|rcsb pdb:1KY6|rcsb pdb:1KY7|rcsb pdb:1KYD|rcsb pdb:1KYF|rcsb pdb:1KYU|rcsb pdb:1QTP|rcsb pdb:1QTS|rcsb pdb:1W80|rcsb pdb:2JKR|rcsb pdb:2JKT|rcsb pdb:2VJ0|rcsb pdb:3HS8|rcsb pdb:6OWO|rcsb pdb:6OXL|reactome:R-MMU-177504|reactome:R-MMU-2132295|reactome:R-MMU-416993|reactome:R-MMU-437239|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-6798695|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8866427|reactome:R-MMU-8964038|hgnc:"MGI:101920"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:KlOjm5d8qxxQkcuD2Hukoj8DLss10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P49615	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-6510052|ensembl:ENSMUSP00000030814	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:cdk5_mouse(display_long)|uniprotkb:Cdk5(gene name)|psi-mi:Cdk5(display_short)|uniprotkb:Cdkn5(gene name synonym)|uniprotkb:Crk6(gene name synonym)|uniprotkb:CR6 protein kinase(gene name synonym)|uniprotkb:Cell division protein kinase 5(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PSSALRE(gene name synonym)|uniprotkb:Tau protein kinase II catalytic subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16750831|imex:IM-26370-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	ensembl:ENSMUSG00000028969(gene)|ensembl:ENSMUST00000030814(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001963"(synaptic transmission, dopaminergic)|go:"GO:0002039"(p53 binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005176"(ErbB-2 class receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007409"(axonogenesis)|go:"GO:0007416"(synapse assembly)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008306"(associative learning)|go:"GO:0008542"(visual learning)|go:"GO:0009611"(response to wounding)|go:"GO:0014044"(Schwann cell development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0016533"(protein kinase 5 complex)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021697"(cerebellar cortex formation)|go:"GO:0021766"(hippocampus development)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030175"(filopodium)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0030549"(acetylcholine receptor activator activity)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030900"(forebrain development)|go:"GO:0031175"(neuron projection development)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031914"(negative regulation of synaptic plasticity)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0034352"(positive regulation of glial cell apoptotic process)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042220"(response to cocaine)|go:"GO:0042501"(serine phosphorylation of STAT protein)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043125"(ErbB-3 class receptor binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048511"(rhythmic process)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0051301"(cell division)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070509"(calcium ion import)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098883"(synapse pruning)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099533"(positive regulation of presynaptic cytosolic calcium concentration)|go:"GO:0099635"(voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P49615|reactome:R-MMU-180024|reactome:R-MMU-399956|reactome:R-MMU-6804756|refseq:NP_031694.1|dip:DIP-29353N|hgnc:"MGI:101765"(identity)	-	-	-	figure legend:Table S3|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2020/12/11	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:mFzCd7zhLyXpxPDQwc1xXCraDQI10090	rigid:moe7roxv0ktxefJeu4YHTeGliH4	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q3UHD9	uniprotkb:P83510	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-7280013|intact:MINT-4138101|ensembl:ENSMUSP00000124681	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:tnik_mouse(display_long)|uniprotkb:Tnik(gene name)|psi-mi:Tnik(display_short)|uniprotkb:Kiaa0551(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16751168|imex:IM-26370-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001156480.1|ensembl:ENSMUSG00000027692(gene)|ensembl:ENSMUST00000159236(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007256"(obsolete activation of JNKK activity)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030033"(microvillus assembly)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001180(Citron-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P83510|reactome:R-MMU-2559580|go:"GO:0055037"(recycling endosome)|dip:DIP-57467N	-	-	comment:mint|function:Stress-activated serine/threonine kinase that may play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. May play a role in cytoskeletal regulation	figure legend:Fig. 4, Fig. S6|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/02/20	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:+Hdc1nFS32RS9/n1kdeF66gw2zs10090	rigid:l/GhMlBLzx+iFL3hPo4MCtl8Mks	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q3UHD9	uniprotkb:Q3UVX5	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-8795045|ensembl:ENSMUSP00000114927	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:grm5_mouse(display_long)|uniprotkb:Grm5(gene name)|psi-mi:Grm5(display_short)|uniprotkb:Gprc1e(gene name synonym)|uniprotkb:Mglur5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16751168|imex:IM-26370-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	go:"GO:0001640"(adenylate cyclase inhibiting G protein-coupled glutamate receptor activity)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002029"(desensitization of G protein-coupled receptor signaling pathway)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006448"(regulation of translational elongation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0001639"(PLC activating G protein-coupled glutamate receptor activity)|go:"GO:0007612"(learning)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0031687"(A2A adenosine receptor binding)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0040013"(negative regulation of locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048170"(positive regulation of long-term neuronal synaptic plasticity)|go:"GO:0050808"(synapse organization)|go:"GO:0050890"(cognition)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:0097449"(astrocyte projection)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:0099530"(G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential)|go:"GO:0099553"(trans-synaptic signaling by endocannabinoid, modulating synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:1902938"(regulation of intracellular calcium activated chloride channel activity)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000162(GPCR, family 3, metabotropic glutamate receptor)|interpro:IPR000202(GPCR, family 3, metabotropic glutamate receptor 5)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR011500(GPCR, family 3, nine cysteines region)|interpro:IPR017978|interpro:IPR017979|interpro:IPR019588|interpro:IPR028082|interpro:IPR038550|reactome:R-MMU-416476|reactome:R-MMU-420499|reactome:R-MMU-6794361|go:"GO:0099583"(neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|ensembl:ENSMUSG00000049583(gene)|ensembl:ENSMUST00000155358(transcript)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|refseq:XP_011239945.1|refseq:NP_001137306.1	-	-	-	figure legend:Fig. 4, Fig. S6|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/02/20	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:pA3IUBq9r3mGn7M8R2qnAaYqaT810090	rigid:l/GhMlBLzx+iFL3hPo4MCtl8Mks	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q3UHD9	uniprotkb:Q14BI2	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-5281533|ensembl:ENSMUSP00000023959	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:grm2_mouse(display_long)|uniprotkb:Grm2(gene name)|psi-mi:Grm2(display_short)|uniprotkb:Gprc1b(gene name synonym)|uniprotkb:Mglur2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16751168|imex:IM-26370-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_001153825.1|ensembl:ENSMUSG00000023192(gene)|ensembl:ENSMUST00000023959(transcript)|go:"GO:0001640"(adenylate cyclase inhibiting G protein-coupled glutamate receptor activity)|go:"GO:0001641"(group II metabotropic glutamate receptor activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0010467"(gene expression)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014048"(regulation of glutamate secretion)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0035095"(behavioral response to nicotine)|go:"GO:0042220"(response to cocaine)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0090461"(glutamate homeostasis)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:2001023"(regulation of response to drug)|interpro:IPR000162(GPCR, family 3, metabotropic glutamate receptor)|interpro:IPR000337(GPCR, family 3)|interpro:IPR001458(GPCR, family 3, metabotropic glutamate receptor 2)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR011500(GPCR, family 3, nine cysteines region)|interpro:IPR017978|interpro:IPR017979|interpro:IPR028082|interpro:IPR038550|mint:Q14BI2|reactome:R-MMU-418594|reactome:R-MMU-420499	-	-	-	figure legend:Fig. 4, Fig. S6|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/02/20	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:51Vq4ZsTylhat6thFK/8MBMIKUI10090	rigid:l/GhMlBLzx+iFL3hPo4MCtl8Mks	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q3UHD9	uniprotkb:P28660	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-771576|uniprotkb:Q3UPY6|uniprotkb:Q80TX0|uniprotkb:Q8CG49|uniprotkb:Q99KY0|ensembl:ENSMUSP00000028386	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:nckp1_mouse(display_long)|uniprotkb:p125Nap1(gene name synonym)|uniprotkb:Membrane-associated protein HEM-2(gene name synonym)|uniprotkb:Brain protein H19(gene name synonym)|uniprotkb:MH19(gene name synonym)|uniprotkb:Nckap1(gene name)|psi-mi:Nckap1(display_short)|uniprotkb:Hem2(gene name synonym)|uniprotkb:Kiaa0587(gene name synonym)|uniprotkb:Nap1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16751168|imex:IM-26370-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	refseq:NP_058661.1|ensembl:ENSMUSG00000027002(gene)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001726"(ruffle)|go:"GO:0001756"(somitogenesis)|go:"GO:0001843"(neural tube closure)|go:"GO:0007354"(zygotic determination of anterior/posterior axis, embryo)|go:"GO:0007492"(endoderm development)|go:"GO:0008078"(mesodermal cell migration)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030903"(notochord development)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031209"(SCAR complex)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031941"(filamentous actin)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0045175"(basal protein localization)|go:"GO:0045176"(apical protein localization)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048340"(paraxial mesoderm morphogenesis)|go:"GO:0048570"(notochord morphogenesis)|go:"GO:0048617"(embryonic foregut morphogenesis)|ensembl:ENSMUST00000028386(transcript)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0098794"(postsynapse)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR019137|mint:P28660|reactome:R-MMU-2029482|reactome:R-MMU-4420097|reactome:R-MMU-5663213|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013423	-	-	-	figure legend:Fig. 4, Fig. S6|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/02/20	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:NIygMTpuScC4fys7MrAWJD7Hd4M10090	rigid:l/GhMlBLzx+iFL3hPo4MCtl8Mks	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q3UHD9	uniprotkb:P35922	intact:EBI-771911|uniprotkb:Q5DU45|ensembl:ENSMUSP00000043466	intact:EBI-645094	psi-mi:agap2_mouse(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Kiaa0167(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:fmr1_mouse(display_long)|uniprotkb:Fmr1(gene name)|psi-mi:Fmr1(display_short)|uniprotkb:Fmr-1(gene name synonym)|uniprotkb:Fragile X mental retardation protein 1 homolog(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wilkinson et al. (2017)	pubmed:28706196|doi:10.1038/s41598-017-05588-3|imex:IM-26370	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16751168|imex:IM-26370-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001028435.1|refseq:NP_001287943.1|ensembl:ENSMUSG00000025422(gene)|ensembl:ENSMUST00000039259(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|go:"GO:0005768"(endosome)	interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032196|interpro:IPR040472|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015030"(Cajal body)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030371"(translation repressor activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034046"("poly(G) binding")|go:"GO:0034644"(cellular response to UV)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043679"(axon terminus)|go:"GO:0003723"(RNA binding)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000301"(negative regulation of synaptic vesicle exocytosis)|go:"GO:2000766"(negative regulation of cytoplasmic translation)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048170"(positive regulation of long-term neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051028"(mRNA transport)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0060996"(dendritic spine development)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070840"(dynein complex binding)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0097386"(glial cell projection)|go:"GO:0097444"(spine apparatus)|go:"GO:0098586"(cellular response to virus)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099577"(regulation of translation at presynapse, modulating synaptic transmission)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1900453"(negative regulation of long-term synaptic depression)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1901254"(positive regulation of intracellular transport of viral material)|go:"GO:1901386"(negative regulation of voltage-gated calcium channel activity)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1902373"(negative regulation of mRNA catabolic process)|go:"GO:1902416"(positive regulation of mRNA binding)|go:"GO:1902737"(dendritic filopodium)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905244"(regulation of modification of synaptic structure)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990635"(proximal dendrite)|go:"GO:1990812"(growth cone filopodium)|go:"GO:0044297"(cell body)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0007417"(central nervous system development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0010369"(chromocenter)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010955"(negative regulation of protein processing)|mint:P35922|interpro:IPR036612|interpro:IPR040148|interpro:IPR041560	-	-	-	figure legend:Fig. 4, Fig. S6|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-brain-cortex)|taxid:10090(Mus musculus brain cortex)	-	2018/01/15	2018/02/20	rogid:yq2lQtfk+FPqgT++CxAx2CS69nE10090	rogid:/NR92KtQt5zwsa+U6lel3sXQyu810090	rigid:l/GhMlBLzx+iFL3hPo4MCtl8Mks	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)